Hub : Genes

PTPN14

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2480 0.0410 2.2e-16 0.116 0.177 0.170 0.187 0.159 6.0e-14 4.6e-21 3.7e-20 3e-22 6.5e-19
2 GTEx Adipose Subcutaneous 0.1440 0.0500 3.5e-03 0.003 NA 0.064 NA 0.035 1.8e-01 NA 5.8e-06 NA 6.6e-04
3 GTEx Artery Tibial 0.1647 0.0545 1.1e-03 0.060 NA 0.099 NA 0.111 1.8e-05 NA 3.3e-08 NA 5.3e-09
4 GTEx Brain Frontal Cortex BA9 0.2869 0.0887 2.5e-03 -0.005 NA 0.006 NA -0.008 4.6e-01 NA 2.2e-01 NA 6.0e-01
5 GTEx Cells Transformed fibroblasts 0.2360 0.0560 1.0e-05 0.104 NA 0.104 NA 0.107 3.6e-08 NA 3.3e-08 NA 2.2e-08
6 GTEx Heart Left Ventricle 0.2258 0.0722 1.8e-03 0.062 NA 0.132 NA 0.058 3.2e-04 NA 1.6e-07 NA 5.0e-04
7 METSIM Adipose 0.0548 0.0216 3.2e-03 0.000 0.011 -0.001 0.008 -0.001 3.7e-01 7.5e-03 6.0e-01 2e-02 6.6e-01
8 TCGA Thyroid Carcinoma 0.0870 0.0360 8.8e-04 0.000 0.026 -0.002 NA -0.002 3.5e-01 1.4e-03 5.1e-01 NA 5.0e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.1 0.1 0.4 0.0 0.6 -0.3 0.2 -0.0 -0.6 -0.2 -0.5
Bipolar Disorder or Schizophrenia 0.8 2.0 4.3 -1.0 -1.3 -2.0 1.2 1.3 -2.1 -1.2 -0.7
Depressed Affect (Nagel 2018) 0.6 1.3 5.4 0.2 0.7 -0.7 0.3 1.3 -1.0 1.3 -2.3
Depression (Nagel 2018) 1.2 1.8 6.8 -1.4 0.8 -0.9 -0.6 0.3 -2.6 0.1 -2.0
Intelligence (Savage-Jansen 2018) 0.7 2.1 6.6 1.8 0.9 0.6 0.4 2.6 1.8 0.1 1.4
Neuroticism (Nagel 2018) 0.4 1.0 3.5 0.8 1.0 -0.8 0.7 0.7 -0.9 0.8 -1.9
Schizophrenia (2018) 1.4 2.8 5.2 -1.3 -2.2 -2.3 1.3 1.6 -2.1 -1.3 -0.4
Schizophrenia vs Biploar Disorder 0.3 0.4 0.8 -0.9 -0.9 0.0 0.3 0.8 -0.6 0.2 -0.7
Worry (Nagel 2018) 0.6 1.3 5.3 1.6 -0.0 -2.3 0.1 -1.0 0.1 -0.9 -0.4
Alzheimer’s Disease (in mother) 0.9 1.0 3.9 0.6 0.4 -1.5 0.2 -1.0 -0.6 2.0 -0.5
Alzheimer’s Disease (in father) 0.8 0.8 4.3 0.7 -0.1 -0.7 -0.4 -0.6 -0.9 -2.1 0.1
Alzheimer’s Disease (including proxy) 0.4 0.6 1.1 0.7 0.8 -0.9 0.3 -1.1 -0.9 0.9 -0.1
Crohns Disease (2017) 1.4 3.1 10.6 0.2 0.9 -1.9 3.3 1.7 -2.3 1.3 0.3
Irritable Bowel Disease (IBD) 0.7 1.6 5.1 0.1 0.9 -1.1 2.0 2.3 -0.9 -0.8 0.1
Ulcerative Colitis (UC) 0.7 1.2 4.8 0.1 0.6 0.2 0.8 2.2 0.7 -1.9 -0.0
Major Depression (MDD) 1.7 2.1 10.9 -0.7 0.7 0.2 0.6 0.9 -3.3 1.2 -1.5
Reaction Time 0.7 1.4 6.2 1.2 0.7 0.9 0.3 -0.1 1.3 -0.7 2.5
Verbal and Numeric Reasoning (VNR) 0.3 0.7 3.3 1.1 1.0 -0.1 0.1 1.8 0.1 -0.3 0.6
Breast Cancer 0.9 2.3 6.5 -2.5 -0.5 2.2 1.0 0.9 -1.2 1.1 -1.4
Ovarian Cancer 0.9 1.2 3.7 0.3 0.1 1.1 0.8 0.7 1.9 -1.4 1.2
Prostate Cancer 0.8 1.1 2.2 1.5 -0.8 -1.2 0.8 1.1 1.4 -0.2 1.0
Age at First Birth 1.5 2.2 7.5 1.1 -0.9 -1.8 -0.2 -1.3 1.1 -2.7 1.4
Bipolar Disorder (2011) 2.5 2.4 6.5 -0.1 -0.0 -0.8 2.5 2.2 -2.3 -0.8 1.2
Body Mass Index (BMI) (2010) 0.5 0.7 3.6 0.1 1.9 1.1 -0.4 0.7 0.2 -0.0 0.5
Coronary Artery Disease (CAD) 0.9 1.1 2.2 -0.7 -0.7 -1.0 -0.9 1.2 -1.4 0.3 -1.5
Crohns Disease (2012) 0.8 1.2 4.9 -1.2 -0.1 -1.0 0.8 0.8 -2.2 1.1 -0.2
Mean Putamen Volume 0.2 0.3 0.8 -0.2 -0.1 -0.3 0.0 -0.9 -0.7 0.8 -0.5
Fasting Glucose 0.7 0.8 3.2 -0.7 -1.8 0.1 1.2 0.6 -0.4 0.4 -0.8
HbA1C 0.3 0.4 1.4 0.4 -0.4 1.2 0.1 -0.8 0.3 0.8 -0.1
HDL Cholesterol 0.4 0.6 1.4 1.2 0.7 -1.1 -0.9 -0.6 -0.1 0.8 0.6
LDL Cholesterol 0.8 1.3 4.5 0.2 0.6 0.8 1.4 2.1 -1.2 0.8 0.7
Lupus 0.5 0.7 4.1 -0.1 0.3 -0.5 -2.0 -0.7 0.3 -0.3 0.9
Neuroticism (2016) 0.3 0.5 1.7 0.8 0.3 -0.4 0.2 -0.5 -0.7 -0.5 -1.3
Primary Biliary Cirrhosis 0.2 0.3 1.5 -0.7 0.4 0.3 -1.2 -0.1 0.0 0.2 0.3
Rheumatoid Arthritis 0.4 0.5 1.9 -0.8 -0.2 0.0 -0.9 -1.4 0.1 0.3 0.6
Schizophrenia (2014) 1.8 4.0 9.1 -1.5 -3.0 -2.5 1.1 1.4 -2.8 -1.6 -1.0
Triglycerides 0.7 1.1 4.2 -0.9 -0.5 1.1 -0.2 2.0 0.5 1.3 -0.4
Type 2 Diabetes (T2D) (2012) 1.0 1.2 2.4 -1.0 -0.8 0.0 -1.5 -1.0 0.7 1.3 -1.5
Ulcerative Colitis 0.5 0.7 3.8 -0.5 -0.3 -0.1 0.4 0.9 0.4 -1.9 0.4
Blood Eosinophil Count 0.1 0.9 4.3 0.1 -1.0 0.5 -0.2 0.8 -0.7 0.1 2.1
Blood Platelet Count 0.1 1.6 8.1 -0.5 -2.0 -0.1 -0.4 -0.1 2.9 0.2 -0.3
Blood Red Count 0.7 6.6 36.2 -0.7 -6.0 -2.0 1.6 -1.3 0.2 -2.6 0.8
Blood White Count 0.4 3.3 9.1 0.0 -3.0 -0.4 1.0 1.8 -1.4 2.0 -2.7
Heel T-Score 0.1 1.1 3.9 -0.4 -2.0 1.3 0.2 1.0 1.1 -1.0 0.3
BMI 0.2 1.1 3.7 0.3 0.8 -0.4 -1.2 1.2 -1.9 1.0 -0.7
Height 0.8 14.8 49.6 2.3 4.2 0.8 4.5 0.5 -7.0 4.5 1.9
Waist Hip Ratio (WHR) 2.4 10.8 34.7 -2.9 1.2 1.3 -1.4 -0.8 -3.1 5.2 -5.9
Systolic Blood Pressure 0.3 1.6 4.3 -0.1 0.5 2.1 1.6 0.5 0.5 2.0 -1.1
Smoking Status 2.9 6.9 18.3 -3.8 -1.0 -1.1 -1.3 1.6 -4.3 0.9 -3.9
Allergy or Eczema 0.4 1.0 6.6 0.1 0.5 0.4 -0.1 -0.1 0.1 1.1 -2.6
Cardiovascular Disease 0.8 2.5 8.5 0.4 -0.0 -0.2 1.1 0.4 -2.4 2.9 -2.0
Hypothyroidism (self reported) 0.3 0.7 2.0 0.1 -1.1 0.1 -0.8 -1.1 -0.3 0.4 -1.4
Respiratory disease 0.9 1.9 3.5 -0.8 1.9 1.4 -1.6 -1.2 0.1 1.6 -1.6
Type 2 Diabetes (T2D) (2018) 0.8 1.5 5.8 -0.2 -2.4 -1.3 0.0 -1.7 -0.3 0.7 -1.0
Lung FEV1/FVC ratio 0.3 1.5 3.6 1.9 -1.2 -1.3 -1.1 1.6 0.7 -0.5 -0.5
Lung FVC 0.7 3.5 11.4 1.9 -1.0 -0.4 2.2 0.6 0.8 -3.4 2.4
Neuroticism 0.6 1.5 5.5 2.3 0.3 -2.3 0.5 -0.5 -0.0 -0.1 -0.8
Chronotype (morning person) 3.2 7.3 20.8 3.0 -2.1 -1.6 3.4 -0.1 0.2 -3.2 4.6
Hair Pigment 0.2 5.7 16.9 -1.9 3.2 1.3 -1.0 -0.8 -2.9 4.1 -1.8
Tanning 0.2 2.0 3.6 0.9 -1.9 -1.9 0.2 -1.4 -0.9 -1.6 1.8
Hand grip strength (left) 1.2 3.2 9.0 1.6 0.1 -1.9 3.0 0.7 -0.5 1.3 2.9
Number of treatments/medications taken 0.9 1.6 4.5 -0.9 0.2 0.8 -0.5 0.9 -2.0 1.2 -2.1
Average weekly spirits intake 0.7 0.9 3.6 -0.2 -0.1 0.7 0.9 -0.4 -1.9 0.5 1.3
Sensitivity / hurt feelings 0.5 0.8 2.5 1.5 0.6 0.1 1.6 -0.7 -0.2 -0.1 -0.8
Frequency of depressed mood in last 2 weeks 2.8 4.0 10.2 -1.9 2.2 -0.1 -0.0 1.4 -3.2 1.2 -3.1
Hearing difficulty/problems: Yes 0.2 0.4 2.4 0.4 -0.4 -0.0 -0.0 1.5 -0.2 0.4 -0.2
Relative age of first facial hair 0.4 0.7 2.0 0.4 -0.7 -1.4 0.1 -0.5 0.5 0.9 1.4
Other serious medical condition/disability diagnosed by doctor 0.9 1.2 6.1 0.5 -0.4 -1.3 0.7 0.1 0.1 -2.5 1.0
Ever used hormone-replacement therapy (HRT) 0.3 0.3 1.3 -0.0 -0.3 -0.4 0.1 -0.0 -0.9 1.1 -0.3
Ever had hysterectomy (womb removed) 1.9 2.1 8.4 -1.2 -1.1 1.6 -0.7 -0.5 -1.5 0.8 -2.9
Systolic blood pressure, automated reading 0.1 0.3 0.8 -0.4 -0.8 0.5 0.6 0.9 0.3 0.6 -0.4
Eye problems/disorders: Diabetes related eye disease 0.5 0.5 1.3 -1.1 -0.7 -1.1 0.1 0.4 -0.8 0.6 -0.3
Angina 0.8 1.0 5.5 -0.8 -0.2 -0.0 0.2 0.2 -1.4 0.1 -2.3
Medication for hormone replacement therapy 0.8 0.9 2.3 -0.7 -0.9 -1.5 -0.8 -1.5 -0.4 -0.2 -1.0
Vitamin and mineral supplements 0.3 0.4 1.1 -1.0 -1.1 0.3 -0.3 -0.5 -0.0 -0.2 -0.7
Supplements: Zinc 0.3 0.3 0.9 0.7 0.5 -0.6 -0.4 -1.0 0.5 0.1 0.0
Medication: Co-codamol 1.2 1.4 8.4 0.2 -0.7 0.4 -1.0 -0.3 -0.3 2.9 -0.8
Medication: Metformin 0.7 0.9 2.6 -0.8 -1.0 0.4 -0.8 1.5 -0.1 0.5 -1.6
Diabetes (father) 1.6 2.0 8.8 -1.4 -3.0 -0.7 -0.5 -1.6 -1.2 0.2 -0.5
Diabetes (mother) 0.3 0.4 1.1 -0.3 -0.3 0.5 0.2 -0.3 0.6 0.9 1.0
Severe depression (siblings) 0.6 0.7 2.8 0.5 1.0 -1.7 -1.0 0.3 -0.3 0.3 -0.1
Pack years adult smoking proportion 1.6 2.4 9.0 -0.4 -0.1 1.6 0.2 1.3 -1.9 1.6 -3.0
Impedance of leg (right) 0.9 4.2 10.8 -1.9 -2.4 -0.1 -2.2 -2.8 3.3 -1.0 0.2
Leg fat-free mass (left) 1.1 5.8 15.6 2.6 2.4 -1.4 3.2 1.8 -4.0 1.6 1.1
Trunk fat percentage 0.1 0.5 1.5 0.0 -1.2 -1.1 -0.3 0.2 0.6 -0.4 -0.5
Hand grip strength (right) 1.2 3.2 12.3 2.1 0.4 -1.1 2.5 1.0 0.6 0.3 3.5
Townsend deprivation index at recruitment 1.2 1.6 5.4 -2.3 -0.4 1.1 -0.5 0.1 -2.1 -0.2 -1.2
Current tobacco smoking 4.0 6.6 15.0 -3.4 0.9 -0.5 -1.9 1.7 -3.9 2.6 -3.5
Average weekly fortified wine intake 0.8 0.9 2.0 0.5 0.8 0.7 1.4 1.2 -1.1 0.6 0.9
Maternal smoking around birth 2.3 3.4 8.1 -1.9 -2.9 -1.6 -0.5 0.7 -2.6 -1.2 -2.0
Fed-up feelings 0.9 1.6 3.4 -0.8 1.0 -1.0 0.4 1.9 -1.2 1.4 -1.9
Frequency of unenthusiasm / disinterest in last 2 weeks 1.1 1.4 4.4 -1.1 0.2 -0.5 -0.4 0.9 -2.1 0.3 -2.1
Relative age voice broke 0.5 0.7 1.7 0.5 -0.3 -0.9 1.2 -1.3 -0.5 0.9 0.6
Taking other prescription medications 0.3 0.5 1.2 -0.2 -1.0 1.1 -0.0 -1.0 -0.5 -0.2 -0.6
Age when periods started (menarche) 0.2 0.5 1.3 0.4 -0.8 -0.4 1.2 -1.0 -0.1 -0.0 0.6
Bilateral oophorectomy (both ovaries removed) 0.7 0.8 1.8 1.3 0.3 1.3 1.3 -0.8 0.1 0.5 0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 1.8 0.7 -0.3 -0.7 0.5 -1.3 -0.9 -1.2 0.4
Tinnitus: Yes, but not now, but have in the past 2.4 2.6 10.9 -1.5 -1.1 1.3 0.0 1.4 -0.7 1.4 -3.3
Qualifications: CSEs or equivalent 0.3 0.4 1.2 0.3 0.6 0.6 0.3 1.1 -1.1 0.4 0.0
Serious illness, injury or assault to yourself 0.9 1.1 3.9 -0.4 -2.0 -1.4 0.4 -0.7 -1.1 0.7 -0.8
High blood pressure 0.6 1.8 4.8 1.3 -0.7 -0.8 1.4 1.5 -2.2 1.3 -0.8
Hayfever, allergic rhinitis or eczema 0.5 1.0 6.4 0.1 1.0 -0.4 -0.3 -0.0 0.4 0.8 -2.5
Multivitamins +/- minerals 0.3 0.4 1.0 0.3 0.6 -1.0 0.4 -0.7 -0.7 -0.5 0.2
Stomach or abdominal pain in last month 1.2 1.4 5.1 -1.6 -0.9 -0.8 -2.3 -0.1 -0.9 1.0 0.7
Supplements: Glucosamine 2.2 2.9 15.2 0.4 3.9 1.1 -1.2 2.0 0.7 -0.1 0.9
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 0.3 0.1 -0.5 0.5 -0.5 0.1 0.4 0.1 0.4
Medication: Atenolol 1.0 1.2 3.5 -0.5 -1.7 -0.9 -0.3 0.1 -1.2 -1.0 -1.9
Medication: Levothyroxine sodium 0.4 0.7 2.5 0.8 -1.2 -0.1 -1.6 -0.7 0.4 -0.8 0.0
Sitting height 1.0 6.9 14.1 1.5 2.6 -0.6 3.7 1.1 -3.8 3.7 1.7
Chronic bronchitis/emphysema (father) 1.9 2.3 4.9 -1.4 -1.5 -0.7 -0.7 -1.1 -2.0 1.7 -2.2
High blood pressure (mother) 0.7 0.9 2.4 1.3 0.8 0.0 1.3 0.5 -0.5 1.6 0.4
Body mass index (BMI) 0.1 0.5 1.7 0.5 0.3 -0.1 -0.4 1.3 -1.2 0.1 -0.4
Impedance of leg (left) 0.9 4.6 10.8 -1.9 -3.1 -0.3 -2.2 -2.5 3.3 -1.4 0.1
Leg predicted mass (left) 1.1 6.0 15.8 2.6 2.4 -1.4 3.1 1.9 -4.0 1.6 1.0
Trunk fat mass 0.1 0.4 1.0 0.7 -0.3 -1.0 0.6 0.6 -0.8 0.4 -0.0
Waist circumference 0.2 0.8 3.2 0.2 0.0 -0.6 -0.2 1.0 -1.8 1.0 -0.6
Number of incorrect matches in round 1.6 2.7 11.1 -0.8 -1.3 -2.0 -1.3 -0.1 -1.5 0.5 -3.3
Past tobacco smoking 0.3 0.5 1.5 0.5 1.1 0.6 0.4 -0.8 0.5 1.2 0.2
Alcohol usually taken with meals 1.8 2.9 11.2 0.7 -0.7 -3.3 0.7 -0.1 0.9 -2.9 1.4
Nervous feelings 0.2 0.4 1.7 1.3 0.1 -0.2 0.7 -0.4 0.5 0.4 0.3
Frequency of tenseness / restlessness in last 2 weeks 1.5 2.3 6.3 -0.6 0.9 -0.5 0.1 1.5 -2.5 2.2 -1.9
Hearing difficulty/problems with background noise 0.6 1.0 3.5 -0.1 1.2 0.4 -1.1 0.2 -0.4 1.3 -1.9
Hair/balding pattern: Pattern 2 1.2 1.6 4.5 1.2 1.6 0.4 0.7 0.9 2.1 -0.3 1.5
Had menopause 1.0 1.3 4.0 -1.9 -0.9 0.9 -0.1 0.8 -0.4 0.2 -2.0
Had other major operations 0.6 0.7 1.7 0.1 -1.0 -0.6 -0.7 1.0 0.4 0.9 -1.3
Forced vital capacity (FVC) 1.0 3.8 12.2 2.7 0.8 -1.8 3.5 -1.0 -1.5 -0.6 1.9
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 1.1 0.8 -0.8 -0.7 1.1 -0.6 -1.0 -0.4 0.3
Ever unenthusiastic/disinterested for a whole week 1.3 1.6 6.1 1.3 0.9 0.2 2.5 1.1 -0.6 0.4 1.5
Qualifications: None of the above 0.4 1.0 3.6 0.5 -1.0 0.9 0.7 -1.0 -0.7 -1.9 0.2
Financial difficulties in last 2 years 0.4 0.6 2.6 0.7 0.1 -0.3 0.1 0.4 -1.1 -1.6 -0.2
Mouth/teeth dental problems 0.3 0.4 1.9 -0.1 1.4 0.2 0.6 0.2 -0.5 0.5 0.8
Heart attack 0.5 0.7 2.0 0.9 0.8 1.1 -0.2 -0.5 1.4 -0.6 0.2
Allergy 0.5 1.1 4.0 0.1 -1.1 -0.4 0.2 -0.1 -0.5 -1.8 2.0
Pain all over the body in last month 0.7 0.8 2.4 0.3 0.6 0.6 0.3 1.1 -1.6 -0.7 1.0
Diabetes (self-reported) 0.8 1.2 3.6 -0.8 -1.9 -1.5 -0.1 -0.9 -0.7 1.1 -0.8
Hayfever/allergic rhinitis (self-reported) 1.1 1.5 3.6 1.3 0.1 -1.6 1.3 -1.9 -0.2 1.0 1.2
Medication: Ramipril 0.9 1.2 2.2 1.2 -1.5 -0.7 1.4 1.1 -0.6 1.1 0.8
Medication: Simvastatin 0.3 0.5 2.1 -0.3 -1.4 -0.2 0.1 -0.4 -0.8 -0.6 -0.7
Fluid intelligence score 0.4 0.8 1.6 1.3 0.1 -0.6 -0.6 0.7 1.1 1.2 0.8
Illnesses of siblings 1.7 2.3 6.2 0.9 2.0 -0.1 -0.3 -2.5 1.8 -1.4 1.4
Neuroticism score 0.9 1.9 6.1 2.5 0.3 -2.4 1.5 0.5 -0.2 0.7 -0.3
Weight 0.5 2.5 7.8 1.8 1.1 -1.1 1.6 1.0 -2.8 1.3 1.0
Impedance of arm (right) 0.5 2.1 7.2 -0.4 -1.2 -1.2 -0.3 -2.3 2.7 -1.1 -0.0
Arm fat percentage (right) 0.0 0.2 0.5 0.4 -0.2 -0.7 -0.1 0.6 -0.1 -0.4 -0.2
Trunk fat-free mass 1.4 8.2 28.5 2.3 2.7 -0.6 3.6 1.6 -5.3 2.3 1.8
Hip circumference 0.5 2.1 7.6 1.8 -0.0 -1.3 1.2 1.1 0.2 -1.2 2.8
Time employed in main current job 0.6 0.7 2.4 -0.2 0.2 -1.5 -1.2 -0.7 -0.4 -0.9 0.4
Alcohol intake versus 10 years previously 0.5 0.7 2.0 -0.1 0.5 0.9 1.0 -1.4 -1.0 -0.5 -0.7
Father’s age at death 0.6 0.8 1.7 -1.2 0.5 1.0 -0.4 -0.4 0.2 -1.3 1.2
Worrier / anxious feelings 1.0 1.8 8.1 0.8 -0.9 -2.8 0.1 -1.0 -1.2 0.1 -1.6
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.2 2.7 0.3 -0.6 -1.6 -1.1 0.2 -1.3 1.0 -1.6
Falls in the last year 1.3 1.7 4.6 -1.5 -1.6 -1.3 -0.8 0.4 -1.1 -2.2 -0.4
Hair/balding pattern: Pattern 3 0.9 1.4 4.4 -1.1 -2.1 -0.6 0.8 -1.1 -1.8 -0.0 -0.2
Number of live births 0.8 1.1 2.7 -0.5 -0.2 0.6 0.7 1.7 0.4 1.6 -1.6
Forced expiratory volume in 1-second (FEV1) 1.0 3.5 11.3 3.4 0.3 -2.0 2.7 -1.1 -0.4 -1.3 1.7
Pulse rate 0.8 1.4 6.4 0.8 -0.8 -1.0 0.0 1.6 -2.5 -0.5 0.1
Happiness 0.9 1.1 1.8 1.3 1.4 -1.0 0.0 1.1 0.8 1.3 0.6
Noisy workplace 0.4 0.5 1.8 0.9 -0.7 -0.2 -0.1 0.4 -0.4 -1.3 -0.6
Qualifications: A levels/AS levels or equivalent 0.6 1.3 4.9 -0.7 2.2 0.5 0.1 0.1 1.2 1.5 -1.1
Serious illness, injury or assault of a close relative in last 2 years 0.7 0.8 4.5 -0.2 -0.9 -0.0 -2.1 0.3 0.2 -0.3 -1.1
Mouth/teeth dental problems: Dentures 0.6 1.1 5.2 -0.8 -2.3 0.1 0.5 0.3 -0.4 -1.4 -0.6
Asthma 0.9 1.7 5.5 -0.5 1.0 0.6 -2.4 -1.4 -0.5 1.9 -1.0
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.8 -0.4 0.2 -0.2 -0.3 0.2 -1.1 0.4 -1.3
Medication: Cholesterol lowering 0.4 0.6 1.3 -0.8 -1.1 -0.8 -0.8 -0.1 -0.5 -0.6 -1.1
Depression (self-reported) 0.5 0.6 2.6 -0.1 0.8 0.4 0.4 0.9 -1.6 -0.2 -0.2
Medication: Lansoprazole 1.1 1.3 4.5 0.1 -0.7 -0.3 -1.4 -0.5 -1.6 0.8 -2.1
Prospective memory result 0.7 0.8 1.8 -0.3 -1.3 -1.2 1.1 -0.1 -0.8 -1.0 -0.6
Lung cancer (father) 0.5 0.6 2.1 -1.1 0.1 -0.4 1.4 0.4 -1.1 0.5 -0.1
Illnesses of mother 0.3 0.4 2.0 0.1 -0.6 -0.8 -0.3 -0.1 0.0 -1.4 0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 1.9 4.1 1.9 0.7 -2.0 2.0 -0.6 -0.7 -1.2 1.0
Pulse wave Arterial Stiffness index 1.1 1.2 3.9 0.2 -2.0 -1.4 0.1 0.0 -1.1 0.5 -1.6
Impedance of arm (left) 0.6 2.6 7.2 -0.9 -1.8 -1.1 -0.4 -2.4 2.7 -1.3 -0.8
Arm fat mass (right) 0.2 0.8 2.9 0.9 0.6 -0.5 0.4 1.2 -1.7 0.4 -0.0
Trunk predicted mass 1.4 8.2 28.9 2.3 2.6 -0.6 3.5 1.7 -5.4 2.3 1.8
Standing height 0.9 8.5 20.2 2.8 1.8 -2.1 4.5 -0.6 -4.2 2.8 2.6
Length of working week for main job 0.7 0.7 3.5 1.0 0.1 -0.6 -0.9 -1.9 0.0 -0.1 -0.4
Exposure to tobacco smoke at home 1.6 1.8 6.0 -1.5 -0.7 0.2 -0.6 -0.9 -1.2 1.7 -2.5
Breastfed as a baby 1.1 1.4 2.9 1.7 0.7 -1.1 -0.5 0.7 1.1 1.6 1.4
Tense / ‘highly strung’ 1.1 1.9 5.1 2.3 1.3 -0.9 1.1 1.8 0.9 1.3 0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 1.5 0.1 0.3 -1.2 -0.5 0.6 -1.2 -0.5 -0.2
Hair/balding pattern: Pattern 4 0.6 1.5 6.1 -0.8 -2.5 0.1 -1.6 -0.4 -0.3 1.5 -0.3
Birth weight of first child 0.9 1.7 9.0 -0.7 0.8 -0.7 -0.5 -1.3 -1.0 3.0 -0.3
Peak expiratory flow (PEF) 1.5 3.4 7.8 2.8 -1.4 -0.8 1.8 -0.3 1.4 -2.6 2.3
Pulse wave reflection index 1.0 1.2 3.4 0.0 -1.8 -1.8 -0.1 -0.0 0.2 1.4 -1.1
Ever highly irritable/argumentative for 2 days 1.6 1.9 5.7 1.1 -2.0 -2.4 1.7 0.8 0.4 -0.9 -0.1
Loud music exposure frequency 1.5 1.6 7.8 -0.4 -0.8 -0.4 -0.1 -2.8 -0.5 -1.9 -0.5
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 2.7 -1.1 1.6 0.9 -0.2 1.2 0.7 -0.3 -0.6
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 1.4 1.2 0.3 0.3 0.6 0.1 0.9 0.2 0.7
Blood clot in the leg (DVT) 0.7 1.0 3.2 0.4 -0.1 -1.1 1.8 0.4 -0.7 1.5 0.4
Medication: Paracetamol 2.6 4.4 17.4 -2.1 -1.4 -0.7 -0.6 -0.3 -4.2 1.3 -2.9
Headache pain in last month 1.7 2.9 10.2 -1.9 0.6 0.4 -1.5 -0.2 -2.1 1.6 -3.2
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 2.0 0.4 1.4 1.3 -0.1 -0.4 0.7 0.1 1.2
Glaucoma (self-reported) 0.6 0.7 3.1 0.0 0.1 0.8 -0.1 0.4 1.4 -1.8 -0.2
Gout (self-reported) 1.0 1.4 4.3 1.6 -0.5 0.1 0.3 1.4 1.1 -2.1 0.9
Hypothyroidism/myxoedema (self-reported) 0.3 0.6 1.4 1.2 -1.1 0.7 -0.0 -0.7 0.6 -0.8 -0.2
Medication: Amlodipine 0.7 0.9 2.7 0.5 -1.6 -0.1 0.7 0.4 1.6 -0.8 -0.7
Medication: Ventolin 100micrograms inhaler 1.0 1.3 2.5 -1.3 0.0 1.5 -0.9 -0.4 -1.4 0.9 -1.6
Birth weight 3.4 7.3 16.8 2.4 4.1 -1.6 2.1 3.7 -2.1 3.1 1.2
Chronic bronchitis/emphysema (mother) 0.5 0.6 1.6 -0.0 -0.8 1.0 0.1 1.3 -1.2 0.4 0.3
High blood pressure (siblings) 3.0 4.3 10.6 0.4 -1.1 0.2 2.8 3.3 -2.4 2.3 -1.9
Forced vital capacity (FVC), Best measure 0.6 2.2 7.2 1.6 1.0 -1.5 2.7 -0.3 -1.7 -0.6 1.1
Body fat percentage 0.1 0.4 1.3 -0.1 -1.1 -0.7 -0.7 0.1 0.7 -0.6 -0.4
Leg fat percentage (right) 0.2 0.6 2.2 -0.5 -1.0 0.2 -1.5 0.3 1.0 -0.7 -0.1
Arm fat-free mass (right) 1.1 5.4 21.3 1.6 1.7 -0.7 2.5 1.8 -4.6 2.3 1.0
Exposure to tobacco smoke outside home 1.8 2.3 8.4 -1.7 -0.3 1.6 -0.7 -2.9 -0.7 0.3 -1.8
Comparative body size at age 10 0.9 2.5 13.0 1.0 3.6 1.7 0.2 1.0 -0.8 0.5 0.8
Number of full brothers 0.6 0.7 2.7 -0.3 -0.4 -1.1 -1.6 -1.1 0.6 -0.3 0.3
Worry too long after embarrassment 0.2 0.3 0.8 0.3 0.9 0.4 0.0 0.5 0.2 0.9 -0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 2.3 3.0 11.9 -2.4 0.7 0.3 0.1 1.1 -3.5 0.2 -2.2
Wheeze or whistling in the chest in last year 2.0 3.6 7.4 -2.1 -0.9 -1.2 -2.7 -0.3 -2.7 0.4 -2.7
Number of children fathered 0.9 1.0 3.7 1.6 0.2 -0.2 -0.4 0.0 1.9 -0.2 1.1
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.2 3.4 0.9 -1.0 -1.2 0.8 -1.2 -1.9 0.5 -0.2
Age at first live birth 2.6 4.7 19.9 2.2 2.5 0.5 0.8 0.3 4.5 -0.2 2.3
Pulse wave peak to peak time 1.1 1.3 5.3 -0.1 2.3 1.3 0.2 -0.3 0.8 -0.1 1.7
Health satisfaction 1.0 1.3 2.9 1.6 1.7 -1.6 0.0 1.3 -0.4 -0.6 -0.1
Shortness of breath walking on level ground 0.9 1.1 5.2 2.3 -0.3 -1.5 -0.1 0.2 -0.1 -1.0 0.6
Qualifications: College or University degree 0.4 1.3 3.8 1.1 -0.3 -1.9 0.2 -0.4 1.3 -0.1 1.9
Eye problems/disorders: None of the above 1.0 1.2 5.9 0.6 2.4 0.9 0.1 -0.0 -0.0 1.1 1.1
Mouth/teeth dental problems: Loose teeth 0.3 0.3 0.7 0.8 0.4 0.7 0.8 0.7 -0.1 0.5 0.0
Emphysema/chronic bronchitis 0.8 0.9 2.4 -0.1 0.1 1.4 0.8 0.7 1.0 -0.5 1.6
Medication for pain relief, constipation, heartburn 2.6 4.5 16.3 1.9 0.6 -0.2 0.2 -0.7 4.0 -2.3 3.2
Neck or shoulder pain in last month 0.5 0.7 1.6 -0.3 -1.2 0.1 -0.8 1.3 -0.9 -1.1 -0.2
Medication: Blood pressure 0.2 0.3 0.8 0.2 -0.7 -0.8 0.7 0.9 0.5 -0.3 0.1
Angina (self-reported) 0.9 1.1 6.7 -0.9 -0.2 0.1 -0.2 -0.1 -1.3 0.1 -2.6
Migraine (self-reported) 0.3 0.4 1.3 1.1 0.5 0.1 0.2 -1.0 0.0 0.4 0.4
Medication: Ibuprofen 0.7 0.9 2.1 -0.9 0.5 0.4 -0.4 1.4 -1.0 0.7 -1.4
Medication: Allopurinol 0.2 0.3 0.7 0.4 0.3 0.8 0.2 0.9 -0.2 -0.5 0.2
Medication: Omeprazole 0.3 0.3 0.6 0.2 -0.8 0.7 0.6 0.5 0.5 0.8 0.1
Medication: Seretide 50 evohaler 0.5 0.6 2.4 0.6 0.2 1.6 -0.4 -0.9 -0.4 -0.6 0.1
Mean time to correctly identify matches 0.4 0.8 2.1 0.9 -0.6 0.7 0.4 -0.2 1.1 -1.0 1.5
Heart disease (mother) 0.3 0.3 1.6 -0.7 0.0 0.4 -1.3 0.5 -0.0 0.2 0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.0 1.2 5.9 -1.1 0.7 0.4 -0.3 0.9 0.1 1.0 -2.4
Whole body fat mass 0.1 0.4 1.1 0.9 -0.1 -0.8 0.6 0.7 -1.0 0.4 -0.0
Leg fat mass (right) 0.1 0.3 0.9 0.5 0.3 -0.2 -0.1 0.7 -1.0 0.5 -0.0
Arm predicted mass (right) 1.0 5.1 20.8 1.4 1.7 -0.7 2.2 1.9 -4.6 2.2 1.0
Pulse rate, automated reading 1.0 3.2 11.0 1.7 1.8 0.5 0.7 3.3 -2.4 1.0 -0.7
Alcohol intake frequency. 0.6 1.4 5.1 -0.3 1.0 2.3 -0.6 0.8 0.4 1.3 -1.5
Comparative height size at age 10 1.1 6.2 17.9 2.1 1.0 -0.3 4.0 -1.1 -4.2 2.3 1.9
Number of full sisters 0.7 0.9 4.1 -0.3 -2.0 -0.4 -1.2 -0.5 -0.5 0.5 -0.8
Suffer from ‘nerves’ 0.5 0.9 1.9 0.9 -0.7 -1.4 0.9 -1.1 -1.2 -0.3 0.4
Overall health rating 1.9 4.1 13.2 -1.0 -1.0 -0.8 -1.8 0.1 -3.2 1.9 -3.6
Chest pain or discomfort 1.2 1.7 6.5 -1.3 0.9 -0.4 -1.4 0.2 -1.4 0.6 -2.5
Had major operations 1.4 1.6 7.1 1.2 -0.4 -1.0 0.6 -0.0 1.2 -2.7 1.3
Age at last live birth 2.1 3.0 10.5 1.0 3.0 0.9 -0.4 -0.3 3.2 0.7 1.4
Family relationship satisfaction 1.5 1.9 8.5 1.7 2.9 0.3 0.7 0.8 1.3 0.8 -0.7
Leg pain on walking 1.2 1.5 8.4 -0.0 -0.6 -1.1 -0.9 0.4 0.6 -2.9 0.7
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 1.3 1.0 -1.0 -1.1 0.9 0.0 -0.7 0.8 -0.8
Commuting to job workplace: Car/motor vehicle 0.7 0.8 2.5 -1.3 -0.4 0.4 0.1 0.9 -0.9 -0.7 -1.6
Illness, injury, bereavement, stress in last 2 years 1.4 1.7 6.6 -0.2 1.1 1.2 1.2 2.6 1.4 0.6 0.9
Medication: Aspirin 1.6 2.1 6.7 -0.9 0.0 0.6 0.8 -0.3 -2.6 2.0 -2.1
Supplements: Vitamin C 0.4 0.5 2.0 0.1 0.0 0.8 0.6 0.7 0.5 -0.3 1.4
Knee pain experienced in last month 1.1 1.7 7.8 -1.4 -0.6 -0.3 -2.8 -1.3 -0.8 0.5 -1.0
Hypertension (Self-reported) 0.6 1.7 6.1 0.6 -0.7 -0.5 1.0 1.2 -2.5 1.5 -1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 3.0 -0.6 1.0 0.7 -1.4 -0.0 -0.8 -0.0 -1.7
Illnesses of father: Heart disease 0.4 0.5 1.3 0.4 -0.7 0.2 -1.1 -1.0 0.7 0.5 -0.6
Illnesses of siblings: Diabetes 1.6 2.0 7.8 -1.4 -2.8 -1.3 -1.2 -0.7 -1.4 0.4 0.0
Smoking status: Previous 0.5 0.8 3.5 0.4 -1.3 -0.9 -0.2 0.1 0.4 -1.9 0.5
Forced expiratory volume in 1-second (FEV1), predicted 1.2 2.5 9.1 1.3 -0.5 -3.0 0.8 -1.5 -1.8 0.2 1.6
Whole body fat-free mass 1.3 7.5 23.9 2.5 2.6 -0.9 3.4 2.0 -4.9 2.0 1.6
Leg fat-free mass (right) 1.1 6.0 15.6 2.7 2.2 -1.5 3.2 2.1 -4.0 1.6 0.9
Arm fat percentage (left) 0.1 0.2 0.5 0.4 -0.4 -0.7 -0.3 0.6 0.1 -0.4 -0.4
Average weekly red wine intake 0.8 1.1 4.8 0.1 1.0 -1.2 -0.7 -0.4 0.1 -0.9 2.2
Handedness (chirality/laterality): Left-handed 0.6 0.8 2.1 -0.3 1.1 0.7 1.4 -0.1 -1.1 0.9 -0.7
Mood swings 0.4 0.7 3.2 0.5 0.7 -0.5 0.3 1.0 -0.6 1.8 -0.4
Loneliness, isolation 1.3 1.9 5.6 0.4 1.5 0.6 1.0 2.4 -1.6 1.5 -0.8
Long-standing illness, disability or infirmity 0.3 0.4 1.7 -0.1 -0.5 -0.5 -0.1 0.5 -1.3 0.6 -0.6
Ever had bowel cancer screening 1.5 1.8 4.0 -1.1 -1.9 -1.6 -0.6 0.8 -1.3 0.1 -2.0
Diabetes diagnosed by doctor 0.9 1.4 4.8 -0.3 -2.2 -1.4 -0.1 -1.3 -0.7 0.8 -1.3
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.1 2.8 0.4 1.0 1.5 -1.4 0.7 0.6 -0.1 -1.7
Friendships satisfaction 1.6 2.0 5.6 2.4 2.0 -0.7 1.6 1.4 0.5 1.1 0.0
Qualifications: nursing, teaching 0.6 0.9 2.5 1.0 0.6 -0.8 1.6 0.0 0.5 1.4 0.5
Commuting to job workplace: Walk 1.6 1.7 5.6 0.5 -2.0 -2.4 -0.3 -1.1 0.0 -0.9 1.3
Eye problems/disorders: Cataract 1.6 1.9 6.9 1.1 -2.6 -1.6 -1.3 0.3 -1.4 -0.8 0.3
Mouth/teeth dental problems: Mouth ulcers 0.5 0.9 2.6 -0.6 1.1 0.9 -1.6 -0.5 1.0 0.2 -0.8
Medication for cholesterol 1.1 1.6 4.9 -0.1 0.6 -0.3 -0.0 0.4 2.2 -1.7 2.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 1.0 5.0 -0.7 -0.7 -0.1 -0.5 -0.8 -2.2 0.7 -0.6
Back pain experienced in last month 1.0 1.4 5.1 -0.8 0.4 1.0 -1.0 -0.1 -1.3 1.3 -2.3
Mineral and other dietary supplements 0.7 1.0 6.7 0.4 -2.6 -0.3 -0.1 -0.5 0.1 0.6 -0.3
Breast cancer (self-reported) 2.1 2.5 8.0 0.6 -2.8 -1.5 1.0 -2.6 -1.4 -0.5 0.2
Asthma (self-reported) 1.3 2.6 7.0 -1.0 1.3 1.0 -2.6 -1.4 -0.6 2.3 -1.5
Osteoporosis (self-reported) 0.2 0.3 0.7 -0.4 -0.3 0.3 0.1 -0.9 -0.5 -0.7 -0.6
Osteoarthritis (self-reported) 0.4 0.5 1.6 1.0 -0.2 -1.3 -0.3 0.2 -0.8 0.2 0.4
Medication: Aspirin 2.3 3.0 11.9 -1.1 -0.1 0.7 1.2 -0.0 -3.5 2.2 -2.0
Medication: Gliclazide 0.4 0.5 1.2 0.8 -0.8 -1.1 0.1 -0.2 -0.0 0.6 -0.9
Illnesses of father: None of the above (group 1) 1.0 1.2 3.8 0.1 0.9 -1.1 1.3 0.9 0.1 -2.0 1.1
Smoking status: Current 3.6 5.7 14.3 -3.1 1.1 -0.0 -1.4 1.8 -3.8 2.5 -3.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.2 6.2 2.4 0.3 -0.9 1.0 -1.6 0.8 -2.5 0.9
Whole body water mass 1.3 7.3 24.5 2.4 2.5 -0.9 3.3 1.9 -5.0 2.1 1.4
Leg predicted mass (right) 1.2 6.2 15.6 2.7 2.3 -1.4 3.2 2.3 -4.0 1.6 0.9
Arm fat mass (left) 0.2 0.9 2.9 1.3 0.5 -0.7 0.7 1.1 -1.7 0.8 -0.1
Number of self-reported non-cancer illnesses 0.2 0.4 1.1 0.3 0.0 -0.1 -0.1 1.1 -1.0 0.7 -0.8
Average weekly champagne plus white wine intake 1.2 1.7 3.5 1.8 0.6 -0.4 1.7 1.9 0.9 1.0 1.3
Miserableness 0.7 1.2 2.9 0.1 0.3 -1.3 0.3 1.0 -1.1 1.7 -1.6
Guilty feelings 0.5 0.7 2.4 0.6 0.6 -1.6 1.0 -0.5 -0.1 1.0 0.8
Wears glasses or contact lenses 0.3 0.4 1.3 0.8 0.0 -0.2 0.7 -0.6 -1.1 -0.0 0.6
Ever taken oral contraceptive pill 0.9 0.9 3.7 -0.7 0.4 -0.0 1.4 0.7 -0.3 1.9 -0.7
Hearing aid user 1.0 1.1 3.3 0.5 -0.8 -1.5 -0.9 1.3 1.8 0.0 0.4
Mother’s age at death 0.4 0.4 1.1 -0.6 0.9 0.5 -0.6 -0.1 1.1 0.2 0.8
Financial situation satisfaction 1.0 1.2 3.5 1.9 0.7 -1.6 -0.2 -0.8 0.9 -1.3 0.3
Tinnitus: Yes, now most or all of the time 0.6 0.7 2.0 0.6 1.4 0.2 -0.4 1.3 0.6 -0.8 -0.1
Commuting to job workplace: Public transport 0.9 1.1 6.1 0.2 1.2 0.7 -0.6 0.0 -0.5 2.5 -0.3
Eye problems/disorders: Glaucoma 1.0 1.2 5.2 -0.3 0.1 0.4 0.2 1.1 2.3 -1.8 0.1
Medication: Blood pressure 1.2 2.3 5.5 1.1 0.6 1.0 1.4 1.0 -2.3 2.3 -1.4
Pain type(s) experienced in last month: Hip pain 2.0 2.5 7.2 -2.6 -0.1 0.0 -1.6 0.5 -1.7 0.3 -2.7
Supplements: Fish oil (including cod liver oil) 0.4 0.5 2.5 -0.3 1.6 -0.2 0.7 -0.4 0.4 -0.4 0.5
High cholesterol (Self-reported) 0.3 0.5 1.2 -0.2 -0.0 1.1 -1.0 -0.8 -0.2 0.2 -1.0
Medication: Bendroflumethiazide 1.2 1.8 5.6 -1.0 0.6 1.9 0.3 1.4 -1.4 0.1 -2.4
Medication: Paracetamol 1.8 2.8 10.0 -1.8 -0.5 -0.5 -0.5 0.3 -3.2 1.2 -2.6
Medication: Lisinopril 0.2 0.3 0.6 0.7 0.8 0.5 0.2 0.6 0.0 0.4 -0.3
Medication: Atorvastatin 0.5 0.6 2.9 0.0 0.1 -0.6 -0.1 0.3 -0.6 1.7 -1.2
Illnesses of father: High blood pressure 2.1 2.6 7.8 0.7 1.6 2.8 0.3 2.4 0.7 1.8 0.3
Alcohol drinker status: Never 0.4 0.5 0.9 -0.7 0.5 0.9 -0.8 0.9 0.5 0.7 -0.5
Ever smoked 0.5 0.8 4.0 -0.8 -0.5 -0.7 -0.3 2.0 0.0 -0.9 -0.1
Basal metabolic rate 1.1 6.2 19.9 2.5 2.1 -1.1 3.1 1.7 -4.5 1.8 1.5
Leg fat percentage (left) 0.2 0.7 2.0 -0.4 -1.4 0.1 -1.3 0.6 0.6 -1.0 -0.2
Arm fat-free mass (left) 1.2 6.0 21.8 2.1 1.7 -0.6 2.6 1.9 -4.7 2.3 1.5
Number of operations (self-reported) 0.9 1.3 3.1 -0.7 -0.6 -0.4 -1.3 1.4 1.8 -1.5 -0.8
Average weekly beer plus cider intake 1.1 1.6 4.5 -0.2 1.6 1.8 -0.4 0.9 -2.1 1.2 0.0
Irritability 1.6 2.7 6.7 2.6 0.2 -2.0 1.6 2.5 0.9 0.7 -0.4
Risk taking 0.9 1.3 4.5 -1.2 -1.6 -2.1 -0.4 0.9 -0.6 0.7 -0.6
Ever had prostate specific antigen (PSA) test 0.5 0.5 2.6 -0.0 -0.7 -0.9 -0.0 0.1 1.6 -0.6 0.0
Fractured/broken bones in last 5 years 1.5 1.9 6.7 -1.3 -0.4 -0.1 0.9 0.9 -2.6 1.6 -1.5
Age started oral contraceptive pill 0.8 1.0 4.1 0.7 0.3 0.4 -1.6 0.3 2.0 -0.4 -0.8
Diastolic blood pressure, automated reading 0.9 2.9 8.0 1.4 1.4 0.7 1.5 2.7 -1.1 2.8 0.0
Ever depressed for a whole week 0.6 0.8 2.0 0.8 0.1 -0.3 1.4 1.4 0.6 -1.1 -0.2
Unable to work because of sickness or disability 0.5 0.6 2.2 -0.9 -0.0 -0.7 -1.5 -0.2 -0.6 0.0 -1.1
Commuting to job workplace: Cycle 2.2 2.6 10.2 1.9 1.4 0.2 0.5 -0.3 2.0 -0.9 3.2
Myopia 1.6 2.4 7.4 -1.0 -0.8 -1.0 -2.7 -1.6 0.5 -2.4 -0.6
Vascular/heart problems diagnosed by doctor 0.6 1.6 5.3 -1.1 0.9 0.4 -1.4 -1.0 2.3 -1.2 0.9
Cholesterol lowering medication 0.7 1.1 2.7 0.8 -1.0 1.5 0.7 -0.2 -0.9 1.6 -1.0
Medication: Omeprazole (e.g. Zanprol) 0.6 0.7 1.4 -0.8 -0.7 1.0 -0.3 0.5 -0.8 1.2 -1.1
Pain experienced in last month 1.3 2.2 5.4 1.8 -0.8 -0.8 2.3 -0.3 1.7 -1.0 1.9
Supplements: Calcium 1.1 1.2 4.1 0.8 1.4 0.4 1.7 -0.1 0.3 2.0 0.3
Basal cell carcinoma (self-reported) 1.8 2.1 8.0 -1.2 -0.3 0.9 -2.8 -0.6 -0.5 2.4 -0.6
Heart attack/myocardial infarction (self-reported) 0.5 0.7 2.0 0.9 1.0 1.0 -0.1 -0.5 1.4 -0.6 0.2
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 2.8 0.6 0.6 -1.0 1.7 0.4 -0.7 1.3 0.4
Heart disease (siblings) 1.0 1.2 2.4 -0.9 0.6 0.6 0.1 1.2 -1.5 1.6 -1.5
Alcohol drinker status: Previous 0.9 1.1 3.3 -1.1 0.2 0.4 -1.2 1.4 -0.0 1.8 -0.7
Pack years of smoking 1.1 1.6 4.6 -0.2 -0.1 1.8 0.1 1.6 -1.3 1.0 -2.1
Impedance of whole body 0.8 4.0 11.3 -1.3 -2.7 -1.0 -1.3 -2.5 3.4 -1.5 -0.1
Leg fat mass (left) 0.1 0.3 1.4 0.4 -0.2 -0.4 -0.0 1.0 -1.2 0.2 -0.1
Arm predicted mass (left) 1.0 5.3 21.3 1.8 1.6 -0.7 2.3 1.9 -4.6 2.1 1.3