Hub : Genes

PTPRN2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2330	0.0440	3.4e-09	0.102	0.098	0.175	0.176	0.182	2.2e-12	6.7e-12	9.3e-21	5.9e-21	1.2e-21
2	GTEx	Whole Blood	0.1860	0.0490	2.8e-04	0.184	NA	0.160	NA	0.174	1.1e-16	NA	1.3e-14	NA	7.3e-16
3	METSIM	Adipose	0.0923	0.0297	3.8e-04	0.054	0.033	0.044	0.057	0.043	1.5e-08	8.8e-06	2.8e-07	6.7e-09	4.3e-07
4	NTR	Blood	0.1276	0.0216	2.2e-16	0.079	0.056	0.097	0.104	0.099	2.9e-24	1.7e-17	1.5e-29	9.9e-32	2.5e-30
5	ROSMAP	Brain Pre-frontal Cortex	0.2849	0.0422	1.3e-15	0.077	0.145	0.215	0.212	0.212	3.6e-10	3.2e-18	3.6e-27	9.1e-27	8.7e-27
6	TCGA	Colon Adenocarcinoma	0.1220	0.0470	7.2e-03	0.016	0.038	0.025	NA	0.004	4.0e-02	2.7e-03	1.3e-02	NA	1.8e-01
7	TCGA	Prostate Adenocarcinoma	0.0674	0.0236	2.3e-03	0.084	0.025	0.067	NA	0.075	4.4e-09	1.1e-03	1.5e-07	NA	2.7e-08
8	TCGA	Soft Tissue Sarcoma	0.1730	0.0590	5.5e-03	-0.004	0.020	0.016	NA	-0.003	7.7e-01	2.3e-02	3.6e-02	NA	5.8e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	1.8	2.9	5.9	0.3	-2.4	-2.0	-1.8	-1.6	-2.1	-1.6	-0.2
Bipolar Disorder or Schizophrenia	1.0	2.4	5.3	0.8	-2.3	-2.0	-1.7	-0.0	-1.7	-1.8	-0.6
Depressed Affect (Nagel 2018)	0.8	1.7	5.2	0.1	-1.9	-1.7	-2.3	-0.0	-0.5	1.1	0.4
Depression (Nagel 2018)	0.4	0.6	1.6	-0.6	-0.7	-0.4	-1.2	-0.4	0.2	1.2	-0.5
Intelligence (Savage-Jansen 2018)	0.2	0.5	2.5	-0.1	-0.9	-0.4	0.1	0.3	1.6	0.7	0.1
Neuroticism (Nagel 2018)	0.7	1.7	5.1	-0.2	-1.8	-1.7	-2.3	-0.7	0.1	1.2	0.4
Schizophrenia (2018)	0.4	0.8	1.4	0.7	-1.0	-0.9	-0.8	1.2	-0.5	-0.9	-0.6
Schizophrenia vs Biploar Disorder	0.4	0.6	1.3	-0.6	-0.9	-0.9	-0.8	1.1	0.4	0.3	0.9
Worry (Nagel 2018)	0.1	0.2	0.6	0.1	-0.6	-0.4	-0.3	-0.8	0.5	0.5	0.1
Alzheimer’s Disease (in mother)	2.1	2.5	5.0	-2.2	-2.1	-1.9	-1.9	-1.1	0.2	0.7	1.2
Alzheimer’s Disease (in father)	2.9	3.1	8.6	2.1	1.9	2.0	2.9	1.6	0.2	-0.8	-1.2
Alzheimer’s Disease (including proxy)	0.1	0.1	0.4	-0.4	-0.7	-0.4	0.2	-0.1	-0.4	-0.2	0.2
Crohns Disease (2017)	0.2	0.4	1.7	-0.1	0.2	0.3	0.2	-1.3	-0.7	-0.3	-0.7
Irritable Bowel Disease (IBD)	0.4	0.9	2.5	0.8	0.6	0.8	0.6	0.2	-1.4	-0.7	-1.6
Ulcerative Colitis (UC)	0.8	1.5	2.7	1.3	0.7	0.8	0.6	1.4	-1.6	-1.2	-1.5
Major Depression (MDD)	0.6	0.7	2.8	-0.0	1.0	0.9	1.7	-0.7	-0.5	-0.4	0.4
Reaction Time	3.6	6.8	15.4	3.9	0.7	1.4	1.1	3.9	-3.2	-3.1	-0.1
Verbal and Numeric Reasoning (VNR)	0.3	0.8	3.4	-0.8	-0.8	-0.7	0.0	0.6	1.8	0.6	-0.8
Breast Cancer	1.3	3.1	9.3	-0.6	-3.0	-3.0	-2.1	-1.2	0.4	0.0	0.6
Ovarian Cancer	0.6	0.8	2.6	0.3	0.8	0.8	0.8	0.8	-0.7	-1.6	-0.6
Prostate Cancer	0.4	0.6	1.2	-1.1	0.7	0.7	1.1	-0.7	0.6	-0.9	-0.4
Age at First Birth	0.2	0.2	1.2	1.1	-0.0	-0.0	0.3	0.4	-0.5	-0.1	-0.4
Bipolar Disorder (2011)	0.6	0.6	3.3	1.8	-0.7	-0.7	-0.7	-0.1	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.2	0.3	1.5	-0.1	0.3	0.2	0.1	-0.5	-0.5	-1.2	-0.6
Coronary Artery Disease (CAD)	0.2	0.2	0.7	0.5	-0.8	-0.7	-0.4	0.2	-0.5	0.0	0.0
Crohns Disease (2012)	1.1	1.7	4.5	-1.6	-0.6	-0.6	-0.8	-1.8	1.1	2.1	1.0
Mean Putamen Volume	0.4	0.5	1.6	1.1	-0.4	-0.1	-0.1	1.2	0.0	0.8	0.1
Fasting Glucose	0.2	0.3	0.7	0.1	-0.6	-0.4	-0.7	-0.3	-0.6	-0.3	-0.9
HbA1C	0.3	0.4	1.0	-0.5	-0.9	-0.4	-0.1	-0.8	1.0	0.1	-0.0
HDL Cholesterol	0.5	0.8	2.3	1.5	-0.6	-0.3	-0.7	1.3	0.8	-0.9	0.6
LDL Cholesterol	0.7	1.0	2.2	1.5	-1.4	-1.2	-1.0	0.1	-0.5	-0.9	0.9
Lupus	0.4	0.5	3.1	0.0	-0.5	-0.3	0.8	1.8	-0.5	-0.1	-0.2
Neuroticism (2016)	1.0	1.5	2.5	-1.3	-0.8	-1.4	-1.4	-1.0	1.4	1.6	0.2
Primary Biliary Cirrhosis	0.2	0.2	0.9	-1.0	-0.1	-0.1	-0.3	-0.6	0.1	0.6	-0.4
Rheumatoid Arthritis	0.5	0.7	1.4	-1.2	0.3	0.5	1.0	-0.8	0.5	-1.0	-0.8
Schizophrenia (2014)	0.6	1.4	2.9	0.2	-1.6	-1.7	-1.5	0.3	-1.0	-1.2	-0.7
Triglycerides	0.8	1.2	3.0	1.7	1.0	1.2	1.2	0.7	-1.2	0.0	-1.0
Type 2 Diabetes (T2D) (2012)	1.1	1.3	3.3	-0.5	1.5	0.5	1.8	-0.9	0.9	-0.0	1.6
Ulcerative Colitis	0.2	0.3	2.1	0.0	-0.1	0.2	-0.0	0.2	-0.8	0.2	-1.4
Blood Eosinophil Count	0.1	0.5	1.8	0.4	-1.0	-0.9	-0.5	0.2	1.4	0.5	0.0
Blood Platelet Count	0.5	5.4	26.9	-2.1	-1.1	-1.5	-0.3	-5.2	1.8	2.2	0.0
Blood Red Count	0.3	2.8	9.7	-2.1	-0.9	-1.4	-2.1	-3.1	-0.3	0.5	0.8
Blood White Count	0.1	0.5	1.9	0.6	0.2	-0.0	0.4	0.3	1.4	1.4	-0.1
Heel T-Score	0.2	1.5	4.1	-0.5	0.6	1.0	1.8	0.9	-2.0	-1.1	1.0
BMI	0.9	5.5	14.8	0.9	3.9	3.0	3.3	0.4	-2.3	-1.6	-0.3
Height	0.1	1.2	4.0	1.1	-1.3	-0.8	-0.6	-0.4	2.0	-0.3	1.1
Waist Hip Ratio (WHR)	0.2	0.7	1.8	-1.3	-0.3	-1.1	0.5	-0.8	0.5	0.9	-0.6
Systolic Blood Pressure	0.3	1.5	6.7	-2.6	-1.0	-0.4	-0.3	-0.6	-0.9	-0.9	1.4
Smoking Status	0.6	1.5	3.1	-1.1	-1.5	-1.5	-0.8	-0.2	0.7	1.5	1.8
Allergy or Eczema	0.2	0.4	1.2	0.3	-0.2	-0.3	0.3	0.8	-1.0	0.6	-1.1
Cardiovascular Disease	0.4	1.2	3.2	-1.8	0.4	0.7	1.1	-1.2	-1.1	-1.5	-0.4
Hypothyroidism (self reported)	0.6	1.3	3.0	0.6	-1.5	-1.2	-1.2	0.4	-1.3	0.2	1.7
Respiratory disease	0.4	0.8	3.2	-1.2	0.5	0.2	1.1	-0.6	-1.8	0.4	0.2
Type 2 Diabetes (T2D) (2018)	0.6	1.1	3.2	1.2	0.8	1.1	1.8	1.3	-0.9	-0.3	0.1
Lung FEV1/FVC ratio	0.1	0.7	2.8	0.3	-0.5	0.0	-0.4	0.5	-0.4	-1.7	1.4
Lung FVC	0.3	1.3	3.6	0.5	-0.6	-0.6	-0.5	1.6	-1.8	-1.9	0.3
Neuroticism	0.8	1.8	5.8	1.2	-2.0	-1.8	-2.4	0.2	-0.3	0.2	0.1
Chronotype (morning person)	2.1	4.8	13.5	3.7	1.8	1.8	0.9	1.3	-2.4	-2.2	-2.3
Hair Pigment	0.0	1.2	3.4	-0.6	1.8	1.7	1.6	-0.4	0.0	0.6	-0.2
Tanning	0.0	0.3	0.9	0.2	-0.8	-0.9	-0.6	-0.6	0.3	0.2	-0.4
Hand grip strength (left)	0.2	0.5	1.5	0.0	-0.8	-0.6	-0.1	1.0	0.3	-0.6	1.2
Number of treatments/medications taken	0.5	1.0	3.9	0.6	-0.7	-0.4	-0.3	-0.2	-2.0	-0.9	1.4
Average weekly spirits intake	3.2	4.0	12.0	2.5	0.8	0.7	0.4	3.5	-2.6	-2.2	-0.8
Sensitivity / hurt feelings	2.7	4.7	15.1	-0.7	-2.9	-2.8	-3.9	-1.6	1.2	0.4	1.1
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.7	-0.4	0.3	0.4	-0.6	-0.9	-0.4	-0.0	-0.8
Hearing difficulty/problems: Yes	1.0	1.6	3.3	-1.7	1.8	1.5	1.2	-1.1	1.0	-0.3	0.4
Relative age of first facial hair	1.3	2.8	12.7	-0.9	-0.9	-1.4	-0.8	-0.3	3.6	2.3	0.5
Other serious medical condition/disability diagnosed by doctor	1.1	1.4	3.4	0.6	-1.5	-1.8	-1.0	-0.1	-1.7	-0.2	-0.9
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.2	1.5	-0.9	-0.9	-1.0	0.5	-0.4	0.1	0.3
Ever had hysterectomy (womb removed)	2.1	2.4	4.9	1.9	-2.2	-2.2	-1.7	0.1	-1.0	-1.1	-0.8
Systolic blood pressure, automated reading	0.7	2.0	8.4	-2.9	0.5	0.8	0.9	-1.0	-0.7	-0.4	2.0
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.4	1.5	0.2	0.1	1.0	0.7	-1.5	0.0	-0.4
Angina	1.1	1.5	4.6	1.3	0.4	0.4	0.3	1.4	-1.6	-2.2	-0.9
Medication for hormone replacement therapy	0.5	0.5	1.3	-0.3	-0.8	-1.1	0.1	-1.0	-0.1	1.1	0.1
Vitamin and mineral supplements	1.4	1.9	6.0	1.0	-1.1	-0.4	-1.4	2.4	-1.0	-0.5	1.8
Supplements: Zinc	0.3	0.4	0.8	-0.5	-0.4	-0.5	-0.6	0.3	0.9	0.7	0.7
Medication: Co-codamol	0.3	0.4	1.8	0.2	0.2	-0.3	-0.5	-0.3	-1.4	-0.3	0.7
Medication: Metformin	0.4	0.5	1.6	1.0	0.4	0.3	0.2	1.3	0.3	0.1	1.0
Diabetes (father)	0.4	0.5	1.3	-1.2	-0.4	-0.8	-0.6	-0.7	-0.5	-0.2	-0.7
Diabetes (mother)	0.8	1.0	1.8	0.7	1.2	0.7	0.3	1.3	-1.2	-0.8	-1.1
Severe depression (siblings)	1.3	1.5	8.4	0.5	0.6	0.7	0.7	0.0	-1.2	-0.7	-2.9
Pack years adult smoking proportion	0.3	0.4	1.7	-0.2	-0.3	-0.4	-0.9	0.3	-0.2	-1.3	-0.4
Impedance of leg (right)	2.3	11.2	15.6	-3.7	-4.0	-3.8	-3.0	-3.9	3.1	3.3	1.5
Leg fat-free mass (left)	1.0	5.4	9.7	3.1	2.9	2.7	2.5	2.3	-1.3	-2.0	-0.4
Trunk fat percentage	0.7	2.9	8.7	0.9	2.7	2.3	3.0	-0.8	-0.8	-0.4	-0.2
Hand grip strength (right)	0.5	1.2	5.2	1.1	-0.0	0.3	1.0	2.3	1.4	-0.0	0.7
Townsend deprivation index at recruitment	1.2	1.7	6.2	-0.0	1.9	1.5	2.5	-1.0	-0.3	-0.7	-0.4
Current tobacco smoking	0.4	0.6	2.0	-0.6	0.5	0.9	0.4	0.7	0.9	0.5	1.4
Average weekly fortified wine intake	0.6	0.7	2.2	-0.7	1.3	1.5	0.4	-0.9	-0.2	0.8	0.2
Maternal smoking around birth	0.2	0.3	0.9	0.0	0.5	0.3	-0.2	-0.0	-0.8	-1.0	-0.8
Fed-up feelings	0.4	0.7	2.0	0.4	-0.2	0.0	-0.9	1.1	0.2	1.4	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.4	-0.7	0.1	0.5	0.0	-0.4	-0.3	0.0	0.1
Relative age voice broke	2.1	3.2	7.0	-2.2	-0.8	-1.2	-0.3	-1.8	2.6	1.7	2.3
Taking other prescription medications	0.8	1.3	5.4	1.1	-0.6	-0.3	0.2	0.2	-2.3	-1.6	0.7
Age when periods started (menarche)	1.5	3.7	13.4	-1.4	-2.0	-2.0	-0.7	-1.1	3.7	0.3	2.1
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	1.2	0.5	-0.6	-0.2	-0.4	0.1	-0.7	-0.7	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.2	0.6	-0.2	0.0	0.3	1.0	-1.1	-0.9	1.5
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	3.0	-1.1	0.9	1.0	0.8	-0.1	1.6	1.7	0.8
Qualifications: CSEs or equivalent	1.1	1.4	4.1	-1.3	2.0	1.8	1.2	-0.7	-0.8	-0.2	-0.0
Serious illness, injury or assault to yourself	0.8	1.0	2.3	0.3	1.5	1.1	1.0	0.0	-1.1	-1.1	-1.1
High blood pressure	0.9	2.6	10.2	-3.2	0.6	0.9	0.4	-2.7	0.4	-1.0	0.9
Hayfever, allergic rhinitis or eczema	0.2	0.5	1.2	0.1	0.9	0.8	1.0	1.1	-0.6	0.4	-0.4
Multivitamins +/- minerals	0.7	0.8	4.7	0.0	0.5	0.0	0.3	-1.3	0.2	0.3	-2.2
Stomach or abdominal pain in last month	0.9	1.1	4.5	0.6	1.5	0.8	-0.1	-0.3	-0.7	-0.6	-2.1
Supplements: Glucosamine	0.6	0.8	1.7	0.7	-1.3	-1.1	-1.2	0.0	-0.9	-0.2	-0.5
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.4	1.6	-0.5	-0.7	0.4	-0.2	-0.5	-0.5	-1.1
Medication: Atenolol	1.5	1.9	3.8	-1.8	-1.6	-2.0	-1.6	-1.5	0.0	-0.8	-0.4
Medication: Levothyroxine sodium	0.5	0.9	4.5	-0.4	-0.7	-0.6	0.0	-0.7	-0.7	0.9	2.1
Sitting height	0.1	0.4	2.1	1.0	-0.2	-0.0	-0.2	0.1	-0.2	-1.4	-0.3
Chronic bronchitis/emphysema (father)	1.5	1.7	3.8	1.9	0.0	0.4	-1.5	1.9	-1.0	-0.3	1.7
High blood pressure (mother)	1.6	2.2	4.2	-2.0	1.4	1.7	1.7	-1.4	-1.0	-1.6	0.2
Body mass index (BMI)	1.8	7.8	19.1	1.9	4.4	3.7	3.9	1.4	-2.2	-1.7	-0.6
Impedance of leg (left)	1.9	9.1	14.7	-3.4	-3.3	-3.2	-2.6	-3.8	2.8	2.8	1.8
Leg predicted mass (left)	1.0	5.5	9.2	3.0	2.9	2.8	2.5	2.3	-1.4	-2.1	-0.4
Trunk fat mass	0.8	3.6	9.6	1.4	2.9	2.6	3.1	-0.0	-0.9	-0.9	0.1
Waist circumference	1.1	4.2	12.9	1.1	3.2	2.7	3.6	0.4	-1.0	-0.8	0.0
Number of incorrect matches in round	0.7	1.2	3.0	-0.3	1.7	1.6	1.3	-0.2	-0.8	1.0	-0.7
Past tobacco smoking	0.7	1.2	3.9	0.4	1.8	2.0	0.6	-0.2	0.2	0.8	-1.2
Alcohol usually taken with meals	1.1	1.8	3.8	-1.2	1.0	0.7	1.7	-1.9	1.2	-0.8	-1.7
Nervous feelings	0.5	0.8	3.4	-0.6	-0.2	-0.2	0.3	-1.9	1.4	1.0	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	3.3	0.1	-0.2	-0.3	-0.8	-0.0	-1.7	-1.8	-0.7
Hearing difficulty/problems with background noise	1.4	2.2	4.9	-2.2	1.3	1.2	1.1	-2.1	1.7	1.0	0.5
Hair/balding pattern: Pattern 2	0.8	1.1	2.7	1.0	-0.8	-1.2	-0.6	0.4	-1.2	-0.9	-1.6
Had menopause	1.7	2.1	5.6	-0.1	-1.9	-2.4	-2.2	-1.2	0.7	0.7	0.1
Had other major operations	1.6	2.0	6.9	2.6	0.4	0.3	1.0	2.1	-1.5	-1.0	-0.5
Forced vital capacity (FVC)	0.2	0.8	2.9	0.9	-0.9	-0.7	-0.4	1.0	-0.4	-1.7	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	3.0	0.7	-1.1	-0.6	-0.1	0.2	-0.9	-0.5	1.7
Ever unenthusiastic/disinterested for a whole week	1.3	1.5	3.2	-1.8	-1.2	-1.4	-1.4	-1.5	-0.9	-0.4	-0.8
Qualifications: None of the above	0.4	0.8	2.0	-0.8	-0.7	-0.4	-1.0	-1.4	-1.4	0.0	-0.2
Financial difficulties in last 2 years	0.3	0.5	1.8	-0.3	0.1	-0.1	-0.4	-1.2	0.3	0.1	-1.3
Mouth/teeth dental problems	1.1	1.7	3.1	1.2	1.6	1.3	1.5	1.1	-1.8	-0.6	-0.7
Heart attack	1.5	1.9	4.6	1.3	-1.3	-0.8	-1.8	1.3	-2.1	-1.3	0.7
Allergy	0.7	1.6	4.5	0.6	-1.3	-1.1	-1.8	-0.0	2.1	0.8	1.1
Pain all over the body in last month	0.4	0.4	1.2	0.1	-0.4	-0.4	-0.5	-0.6	1.1	1.1	-0.0
Diabetes (self-reported)	0.4	0.7	2.2	-0.0	1.2	1.1	1.5	0.1	-0.3	-0.2	0.7
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.3	-0.0	0.5	0.2	0.9	-0.3	-0.3	0.9	-1.5
Medication: Ramipril	0.3	0.4	1.8	-0.2	0.9	1.3	0.2	-0.2	0.1	-0.7	0.5
Medication: Simvastatin	0.1	0.2	0.5	0.3	-0.7	-0.3	0.1	-0.3	-0.1	-0.0	0.6
Fluid intelligence score	0.6	1.3	4.3	1.2	-1.0	-1.0	0.2	2.1	0.7	-0.3	-1.4
Illnesses of siblings	0.3	0.4	2.4	0.4	-0.5	-0.4	0.1	-0.2	1.5	-0.2	-0.6
Neuroticism score	0.5	1.0	3.1	1.0	-1.4	-1.2	-1.8	0.1	-0.1	0.2	-0.0
Weight	1.1	5.2	11.4	2.2	3.4	3.0	3.3	1.0	-1.3	-1.7	-0.0
Impedance of arm (right)	1.1	5.2	11.3	-1.8	-2.9	-2.6	-2.0	-3.4	2.4	1.6	-0.0
Arm fat percentage (right)	1.6	6.4	15.8	1.8	3.9	3.4	4.0	0.5	-1.7	-1.4	-0.6
Trunk fat-free mass	0.4	2.5	5.0	2.2	1.5	1.5	1.4	1.9	-1.2	-1.8	0.1
Hip circumference	0.7	3.2	8.5	0.8	2.9	2.6	2.8	-0.4	-1.0	-0.8	-0.3
Time employed in main current job	1.5	1.8	7.3	-0.3	0.7	0.5	-0.0	-1.4	0.7	1.9	2.7
Alcohol intake versus 10 years previously	1.5	2.3	4.9	-2.2	-1.3	-1.8	-1.8	-2.1	0.6	-0.2	-0.6
Father’s age at death	1.5	2.1	5.4	0.7	-2.2	-2.3	-1.5	0.8	1.5	0.5	-0.0
Worrier / anxious feelings	0.6	1.0	2.8	0.5	-0.7	-0.3	-0.3	-1.1	1.7	0.9	-1.7
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.9	2.4	0.4	1.2	1.1	0.8	-0.2	-1.0	-0.1	-1.6
Falls in the last year	0.6	0.9	3.3	-1.4	0.5	0.1	-0.7	-1.8	0.2	0.6	-0.8
Hair/balding pattern: Pattern 3	0.4	0.6	2.6	-0.8	0.6	0.5	1.6	-0.7	0.4	-0.4	-0.0
Number of live births	0.7	1.0	3.9	0.5	-0.0	0.5	-0.1	2.0	-0.6	0.6	1.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	3.5	0.4	-0.5	-0.3	-0.1	0.7	-0.7	-1.9	-0.4
Pulse rate	0.1	0.2	1.0	1.0	-0.2	-0.2	-0.4	0.1	0.8	0.3	-0.1
Happiness	0.7	0.9	3.4	-1.8	0.5	0.5	0.5	-1.2	0.0	0.3	-1.2
Noisy workplace	0.2	0.3	0.9	-0.1	-0.4	-0.7	-0.5	-0.9	-0.4	-0.3	-0.5
Qualifications: A levels/AS levels or equivalent	0.4	1.0	2.5	-0.1	0.9	0.4	1.6	1.1	1.5	0.7	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.7	-1.0	0.4	0.4	0.1	-0.6	0.1	0.2	-1.6
Mouth/teeth dental problems: Dentures	0.8	1.4	2.7	-1.0	-1.6	-1.6	-1.6	-0.8	0.3	0.5	-1.2
Asthma	0.5	1.0	3.0	-0.9	1.0	0.8	1.7	-0.8	-1.3	-0.2	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	2.4	0.2	0.6	0.5	0.0	1.0	-1.1	0.6	1.5
Medication: Cholesterol lowering	1.3	2.0	5.6	1.8	-1.3	-0.5	-1.2	1.1	-2.4	-1.3	0.8
Depression (self-reported)	0.5	0.5	1.7	0.0	-0.5	-0.8	-0.8	0.4	-1.0	-1.3	-0.3
Medication: Lansoprazole	0.8	0.9	2.7	1.7	0.1	0.1	-0.4	1.5	0.0	-0.2	1.5
Prospective memory result	0.4	0.5	1.3	0.4	1.1	0.9	0.2	-0.8	-0.0	0.8	0.5
Lung cancer (father)	0.8	0.9	3.5	0.3	-1.3	-1.2	-1.9	0.1	0.4	0.4	0.4
Illnesses of mother	0.4	0.5	2.4	1.6	0.3	0.3	-0.3	0.1	0.7	0.9	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	5.8	0.6	0.7	0.8	1.0	1.1	-1.4	-2.4	-0.5
Pulse wave Arterial Stiffness index	1.5	1.7	5.3	-2.3	0.2	0.3	-0.6	-1.8	1.2	1.8	0.1
Impedance of arm (left)	1.2	5.3	10.2	-2.3	-2.7	-2.5	-1.6	-3.2	2.7	2.2	0.2
Arm fat mass (right)	1.5	6.3	14.1	2.0	3.8	3.3	3.7	0.9	-1.8	-1.9	-0.4
Trunk predicted mass	0.5	2.6	5.4	2.3	1.5	1.6	1.4	2.0	-1.3	-1.9	0.1
Standing height	0.2	1.5	4.0	0.3	-2.0	-1.5	-1.0	-0.9	1.6	-0.2	1.2
Length of working week for main job	1.0	1.1	6.4	0.1	-0.1	-0.2	-0.2	-0.6	0.9	-2.5	0.9
Exposure to tobacco smoke at home	0.3	0.3	0.7	-0.0	-0.8	-0.7	-0.8	-0.4	-0.7	-0.2	0.1
Breastfed as a baby	0.6	0.8	2.9	-0.3	-0.7	-0.4	-0.8	-0.9	-0.4	0.9	-1.7
Tense / ‘highly strung’	0.3	0.6	2.3	0.9	-0.4	-0.5	0.3	0.7	-0.7	0.0	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	5.0	2.2	0.0	0.5	0.4	1.7	-1.1	-1.0	1.1
Hair/balding pattern: Pattern 4	0.5	1.1	4.0	1.0	0.9	1.1	0.1	2.0	-1.1	-0.1	0.9
Birth weight of first child	0.7	1.3	2.8	0.6	1.0	1.2	1.7	1.2	-1.0	-1.6	0.4
Peak expiratory flow (PEF)	0.6	1.5	6.2	-1.1	0.0	0.1	0.9	-0.6	-1.6	-2.5	-0.9
Pulse wave reflection index	1.4	1.7	7.9	-2.8	0.4	0.3	-0.4	-1.6	1.0	1.4	0.1
Ever highly irritable/argumentative for 2 days	1.4	1.7	5.7	0.7	0.4	0.1	0.7	2.4	-2.0	-1.6	-0.3
Loud music exposure frequency	2.4	2.6	7.5	-2.7	0.0	-0.2	0.4	-2.1	1.7	1.2	2.1
Qualifications: O levels/GCSEs or equivalent	1.3	2.0	5.9	1.4	0.6	0.5	1.4	2.4	1.0	0.0	2.1
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.0	0.9	-0.3	-0.2	0.2	-0.1	0.0	0.2	1.0
Blood clot in the leg (DVT)	0.6	0.7	3.5	-0.0	0.3	0.1	0.7	-0.5	-1.1	-0.7	-1.9
Medication: Paracetamol	1.1	1.8	6.0	-0.5	-1.2	-1.2	-2.5	0.3	-1.5	0.4	1.7
Headache pain in last month	1.1	1.8	4.5	1.3	-0.8	-0.4	-2.1	1.0	-1.4	-2.1	0.4
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	1.7	0.3	1.2	0.5	1.0	0.6	1.3	0.7	-1.3
Glaucoma (self-reported)	1.2	1.5	4.9	-1.7	0.1	0.2	0.9	-2.2	1.0	1.0	1.1
Gout (self-reported)	0.6	0.8	1.8	1.4	-0.9	-0.7	-1.3	0.1	-0.5	1.0	0.9
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	2.4	0.3	-0.9	-0.7	-0.4	-0.1	-0.8	0.6	1.6
Medication: Amlodipine	0.5	0.7	1.8	-0.7	-1.1	-0.9	-0.7	-1.3	0.6	0.2	-0.6
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.8	-0.6	0.6	0.3	0.9	-0.4	-1.3	-0.7	-0.3
Birth weight	0.8	1.7	3.5	-1.3	1.8	1.9	1.5	-1.1	-0.7	-0.4	-1.0
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.7	-0.2	0.1	-0.0	0.4	1.3	0.2	0.3	1.2
High blood pressure (siblings)	0.7	1.0	3.5	-1.9	0.1	0.1	-0.5	-1.1	-1.4	-0.2	1.0
Forced vital capacity (FVC), Best measure	0.3	1.0	5.1	0.5	0.4	0.4	0.8	0.8	-1.0	-2.3	-0.3
Body fat percentage	0.9	3.4	10.3	1.0	3.0	2.4	3.2	-0.5	-0.9	-0.4	0.1
Leg fat percentage (right)	0.7	2.5	7.6	0.3	2.7	2.0	2.8	-0.4	-0.7	0.1	0.3
Arm fat-free mass (right)	0.7	3.4	5.1	2.2	2.3	2.1	2.0	1.9	-1.4	-1.7	0.3
Exposure to tobacco smoke outside home	1.2	1.7	3.2	-1.8	-0.5	-0.5	-1.2	-1.7	1.3	1.1	1.5
Comparative body size at age 10	0.8	2.3	4.5	-1.5	2.1	1.7	2.1	-1.6	0.5	0.7	1.1
Number of full brothers	0.4	0.5	1.3	-0.5	0.3	0.4	-0.4	1.1	-0.9	0.5	1.2
Worry too long after embarrassment	0.4	0.6	1.4	-1.2	-0.8	-0.9	-0.8	-0.2	0.4	0.8	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	0.7	-0.8	0.2	0.1	0.1	-0.8	0.0	-0.3	0.8
Wheeze or whistling in the chest in last year	0.9	1.7	3.6	1.4	1.5	1.3	1.5	1.0	-1.9	-0.7	-0.0
Number of children fathered	0.5	0.6	1.7	0.1	-0.5	-0.6	-1.0	-0.2	1.3	0.4	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	2.5	-1.1	0.5	0.8	-0.0	0.1	0.8	0.2	1.6
Age at first live birth	0.7	1.3	4.1	-2.0	0.3	0.3	0.5	-2.0	1.1	-0.6	-0.6
Pulse wave peak to peak time	1.4	1.6	5.6	2.4	-0.4	-0.5	0.5	1.6	-0.9	-1.8	-0.1
Health satisfaction	0.3	0.4	1.2	-0.4	-0.2	-0.5	-0.4	-0.7	-0.7	0.7	-1.1
Shortness of breath walking on level ground	0.3	0.4	1.3	-0.1	1.1	1.0	0.1	0.9	-0.2	0.2	-0.0
Qualifications: College or University degree	0.4	1.1	3.3	0.2	0.8	0.9	0.7	-0.6	1.4	1.8	-1.2
Eye problems/disorders: None of the above	0.5	0.6	1.4	-0.1	1.0	1.2	0.2	0.9	0.5	-0.6	-0.7
Mouth/teeth dental problems: Loose teeth	2.4	2.9	10.2	-2.7	-1.0	-0.8	-1.5	-3.2	1.0	-0.9	-0.0
Emphysema/chronic bronchitis	0.8	0.9	2.3	-1.4	0.2	-0.1	0.3	-1.3	-1.5	-1.0	0.3
Medication for pain relief, constipation, heartburn	0.7	1.1	2.8	-1.3	0.1	-0.0	1.7	-1.3	1.3	0.2	-1.0
Neck or shoulder pain in last month	0.3	0.4	1.2	-0.8	-0.2	-0.1	-1.1	-0.6	-0.8	0.3	-0.7
Medication: Blood pressure	0.3	0.5	2.1	-0.5	-0.3	0.2	-0.6	-0.8	-0.6	-0.5	1.4
Angina (self-reported)	1.0	1.4	3.8	1.2	0.0	0.1	0.1	1.4	-1.7	-1.9	-0.7
Migraine (self-reported)	1.0	1.2	3.2	-0.8	-1.3	-1.1	-1.8	1.0	-0.8	-0.2	1.1
Medication: Ibuprofen	1.2	1.4	3.6	1.3	0.6	0.6	0.4	1.7	-1.6	0.1	1.9
Medication: Allopurinol	1.0	1.4	5.0	0.3	-1.7	-1.4	-2.2	-0.3	-0.9	0.5	0.2
Medication: Omeprazole	0.5	0.6	3.1	0.7	0.5	0.5	0.2	0.2	-0.5	-1.8	-0.7
Medication: Seretide 50 evohaler	1.2	1.4	8.0	-0.2	-0.4	-0.4	-0.1	-1.3	-2.8	-1.1	0.2
Mean time to correctly identify matches	2.6	5.0	9.5	3.0	1.7	2.2	2.0	3.1	-2.2	-2.1	-0.1
Heart disease (mother)	0.3	0.4	1.6	0.2	-0.8	-1.3	-0.7	0.1	0.3	-0.1	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.1	0.3	1.4	1.3	0.6	1.2	0.5	0.7	0.2
Whole body fat mass	1.1	4.8	12.7	1.7	3.4	2.9	3.6	0.5	-1.2	-1.2	0.2
Leg fat mass (right)	1.1	4.4	11.8	1.6	3.4	2.8	3.3	0.5	-1.2	-0.9	-0.1
Arm predicted mass (right)	0.6	3.3	5.5	2.1	2.3	2.2	2.0	1.8	-1.2	-1.6	0.4
Pulse rate, automated reading	0.1	0.4	0.9	0.6	0.8	1.0	0.7	0.4	0.1	0.1	0.6
Alcohol intake frequency.	0.9	2.2	6.5	-2.5	0.7	0.1	-0.1	-2.3	0.2	0.2	-2.3
Comparative height size at age 10	0.3	1.7	6.0	2.0	-0.1	0.3	0.1	0.5	-2.5	-1.8	0.1
Number of full sisters	1.6	2.0	8.0	1.5	-0.4	-0.8	-1.1	1.8	-2.8	-0.5	0.3
Suffer from ‘nerves’	0.2	0.3	1.5	-0.6	-0.0	0.1	0.5	-1.2	-0.4	0.6	0.3
Overall health rating	0.4	0.9	2.3	0.8	0.9	0.8	1.0	-0.2	-1.5	0.1	-1.2
Chest pain or discomfort	1.5	2.1	4.6	1.8	1.2	1.1	1.3	1.6	-1.3	-2.1	-0.9
Had major operations	0.8	1.0	2.1	-0.3	1.5	0.9	0.9	-0.5	-1.3	-0.3	-1.3
Age at last live birth	0.3	0.5	2.6	-1.6	-0.4	-0.0	-0.5	-0.9	0.2	0.2	0.0
Family relationship satisfaction	1.4	1.7	5.7	0.2	-1.0	-0.9	-0.8	0.0	-2.4	-1.7	-1.4
Leg pain on walking	0.4	0.5	1.2	1.1	0.7	0.7	-0.8	0.5	-0.6	0.8	0.4
Qualifications: NVQ or HND or HNC or equivalent	2.3	2.8	6.7	-0.8	2.6	1.9	1.8	-0.4	-2.1	-1.6	-1.1
Commuting to job workplace: Car/motor vehicle	1.0	1.2	6.2	-1.1	-0.0	0.2	0.6	-1.2	0.3	-0.4	2.5
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.6	1.2	-0.6	-0.3	0.1	1.3	-0.3	0.1	0.8
Medication: Aspirin	0.9	1.2	3.6	1.5	1.0	0.9	-0.1	0.8	-0.8	-0.3	-1.9
Supplements: Vitamin C	1.5	1.8	6.1	-0.9	-0.3	-0.2	-0.0	-1.3	2.3	2.5	-0.5
Knee pain experienced in last month	0.4	0.6	1.0	1.0	0.4	0.3	-0.9	0.6	-1.0	0.4	-1.0
Hypertension (Self-reported)	0.9	2.4	9.4	-2.8	0.2	0.5	-0.3	-3.1	0.3	-0.9	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	4.1	1.1	0.3	0.1	-0.1	1.1	-0.5	-2.0	-1.4
Illnesses of father: Heart disease	1.5	2.0	5.5	0.5	-1.7	-2.1	-2.3	-0.1	-0.9	-1.2	-1.0
Illnesses of siblings: Diabetes	1.0	1.2	3.5	-0.1	1.8	1.9	1.2	0.4	-0.6	0.9	0.0
Smoking status: Previous	0.8	1.2	4.4	-0.2	-1.8	-2.1	-0.6	-0.4	-0.1	-0.3	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.4	-1.2	0.3	0.4	0.7	-0.4	0.2	-0.8	0.2
Whole body fat-free mass	0.7	4.0	8.2	2.9	2.1	2.1	1.9	2.3	-1.5	-2.0	0.0
Leg fat-free mass (right)	1.2	6.5	11.6	3.4	3.1	2.9	2.6	2.4	-1.7	-2.5	-0.5
Arm fat percentage (left)	1.6	6.2	16.5	1.6	3.9	3.4	4.1	0.5	-1.5	-1.0	-0.4
Average weekly red wine intake	1.3	1.9	7.2	2.7	-1.2	-1.2	-0.9	1.5	-1.0	-1.0	0.2
Handedness (chirality/laterality): Left-handed	2.0	2.4	6.0	-0.4	-2.3	-2.2	-2.4	-1.4	-0.7	-0.2	0.2
Mood swings	0.7	1.2	3.9	-0.2	-1.3	-1.5	-2.0	-0.8	-0.1	0.4	-1.0
Loneliness, isolation	0.1	0.2	0.7	0.1	-0.2	-0.2	-0.2	-0.9	-0.5	-0.2	-0.2
Long-standing illness, disability or infirmity	0.8	1.2	3.2	0.9	0.0	-0.5	1.2	-0.7	-1.6	-1.8	-0.8
Ever had bowel cancer screening	0.6	0.7	1.1	0.8	0.9	0.6	1.0	1.1	-0.5	-1.0	-0.3
Diabetes diagnosed by doctor	0.3	0.5	1.4	0.8	0.7	0.8	1.2	0.7	-0.1	-0.2	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	2.6	0.4	-1.6	-1.2	-0.7	-0.4	1.5	0.7	0.2
Friendships satisfaction	1.6	2.0	3.9	-0.8	-1.9	-1.8	-2.0	0.1	-1.3	-0.1	-1.6
Qualifications: nursing, teaching	0.5	0.7	3.7	1.2	0.1	0.1	-0.6	1.9	-0.1	-0.3	0.7
Commuting to job workplace: Walk	1.5	1.6	4.3	-0.5	2.0	1.4	1.1	-0.4	-1.1	-0.2	-2.1
Eye problems/disorders: Cataract	0.1	0.1	0.6	0.6	-0.1	-0.1	-0.7	0.4	-0.3	0.1	0.0
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	3.2	0.8	-0.4	0.0	-0.1	0.9	1.5	1.3	1.8
Medication for cholesterol	0.4	0.6	2.1	1.0	0.6	0.7	-0.4	1.4	0.5	0.0	0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.3	1.3	0.7	0.9	-0.1	1.5	0.1	-0.0	1.0
Back pain experienced in last month	0.6	0.9	1.9	-0.1	-0.8	-1.2	-0.7	-0.5	-1.4	-0.8	-1.3
Mineral and other dietary supplements	0.2	0.3	0.8	-0.4	-0.0	0.3	-0.9	-0.2	-0.6	-0.4	0.9
Breast cancer (self-reported)	0.2	0.2	0.6	-0.0	0.5	0.6	0.4	0.1	-0.4	0.4	-0.8
Asthma (self-reported)	0.5	1.1	3.2	-0.6	1.0	0.8	1.6	-0.5	-1.8	-0.6	-0.4
Osteoporosis (self-reported)	0.9	1.1	2.8	-0.9	-1.0	-1.1	-1.2	-1.7	-0.9	-0.7	0.2
Osteoarthritis (self-reported)	1.7	2.3	8.9	1.7	0.9	1.2	1.4	0.3	-3.0	-0.6	-1.2
Medication: Aspirin	0.8	1.1	2.4	1.5	1.0	1.2	-0.2	1.1	-0.6	-0.0	-1.5
Medication: Gliclazide	0.4	0.5	2.8	0.0	-0.1	0.2	0.7	0.2	1.7	0.5	0.1
Illnesses of father: None of the above (group 1)	0.4	0.5	2.4	-0.7	-0.3	-0.2	0.8	-1.5	0.4	0.4	-0.1
Smoking status: Current	0.3	0.5	1.8	-0.5	0.1	0.6	0.2	0.8	0.7	0.1	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	2.9	0.3	1.5	1.2	1.7	0.5	-0.6	-0.7	-0.8
Whole body water mass	0.7	4.2	8.7	3.0	2.2	2.2	1.9	2.3	-1.5	-2.1	0.0
Leg predicted mass (right)	1.3	6.8	11.9	3.5	3.1	3.0	2.7	2.5	-1.8	-2.6	-0.4
Arm fat mass (left)	1.5	6.3	14.7	2.0	3.7	3.3	3.8	0.9	-1.7	-1.7	-0.3
Number of self-reported non-cancer illnesses	0.9	1.5	8.3	-0.6	0.3	0.2	1.0	-1.1	-2.9	-0.9	-0.5
Average weekly champagne plus white wine intake	0.1	0.2	0.5	-0.4	-0.4	-0.3	-0.1	-0.7	0.4	0.2	-0.7
Miserableness	0.4	0.6	3.1	0.2	-0.2	0.6	-0.4	1.0	-1.8	-0.6	0.2
Guilty feelings	0.3	0.5	1.9	0.4	-0.1	0.1	-1.4	0.3	-0.2	1.2	0.5
Wears glasses or contact lenses	2.9	3.3	6.5	-2.5	1.1	0.9	1.7	-2.1	2.2	2.5	-0.3
Ever taken oral contraceptive pill	0.7	0.8	2.4	-1.5	-0.3	-0.7	0.3	-1.5	0.3	1.0	-0.4
Hearing aid user	0.7	0.8	1.7	0.9	1.1	1.2	1.3	1.0	0.1	0.8	-0.4
Mother’s age at death	0.8	0.9	2.2	0.3	0.6	0.8	1.0	0.5	1.2	1.2	-1.5
Financial situation satisfaction	0.5	0.6	1.9	-0.6	-1.0	-0.5	-1.4	-0.2	-0.7	-0.3	0.9
Tinnitus: Yes, now most or all of the time	0.9	1.0	2.6	-1.2	-0.4	-0.4	-1.4	-1.6	-0.5	-1.2	-0.3
Commuting to job workplace: Public transport	1.0	1.2	2.8	1.6	0.3	0.3	0.4	1.7	0.3	-1.4	-1.3
Eye problems/disorders: Glaucoma	1.0	1.1	2.1	-1.5	-0.8	-0.9	0.4	-1.1	1.2	1.0	1.4
Medication: Blood pressure	0.4	0.7	1.7	-1.2	0.5	0.5	0.7	-1.3	-0.0	-1.2	-0.2
Pain type(s) experienced in last month: Hip pain	1.6	2.0	5.1	0.5	-1.2	-1.2	-1.0	1.3	-2.2	-2.3	0.8
Supplements: Fish oil (including cod liver oil)	0.6	0.7	3.1	0.4	0.6	0.2	1.5	0.0	0.3	-0.3	-1.8
High cholesterol (Self-reported)	0.3	0.6	1.6	0.4	-0.7	-0.1	0.1	0.0	-1.2	-1.3	-1.0
Medication: Bendroflumethiazide	0.5	0.7	2.4	0.4	-0.6	-0.1	-0.3	-0.0	-1.0	-1.2	1.6
Medication: Paracetamol	0.9	1.4	5.5	-0.4	-1.3	-1.2	-2.3	0.2	-1.3	-0.4	0.7
Medication: Lisinopril	2.2	2.9	9.9	-0.4	-3.1	-2.9	-1.5	-0.8	0.4	0.2	1.3
Medication: Atorvastatin	1.1	1.4	4.7	0.8	0.2	0.3	0.2	1.4	-2.2	-1.5	-1.2
Illnesses of father: High blood pressure	0.6	0.7	2.8	-1.7	0.1	0.2	-0.3	-0.2	0.8	0.2	1.4
Alcohol drinker status: Never	0.7	0.9	3.6	-0.6	0.5	0.4	0.1	-1.9	0.4	0.8	-1.4
Ever smoked	0.4	0.8	1.5	-0.8	-1.1	-1.2	-0.3	1.0	-0.2	-0.6	1.2
Basal metabolic rate	0.8	4.6	8.2	2.9	2.5	2.4	2.4	2.1	-1.5	-2.1	0.0
Leg fat percentage (left)	1.0	3.5	10.2	0.5	3.2	2.5	3.2	-0.3	-0.7	-0.1	0.6
Arm fat-free mass (left)	0.8	3.8	8.0	2.8	2.1	2.1	2.0	1.8	-1.5	-2.0	0.3
Number of operations (self-reported)	0.4	0.6	2.5	0.9	0.1	-0.5	0.3	0.4	-1.6	-0.7	-0.6
Average weekly beer plus cider intake	0.6	0.9	1.5	1.2	-1.1	-0.8	-0.8	0.9	0.9	0.7	1.0
Irritability	0.3	0.5	1.2	0.1	-1.0	-1.1	-0.9	-0.6	-0.3	0.7	0.3
Risk taking	0.7	1.1	6.7	-0.5	-0.0	-0.7	-0.0	-0.5	-0.9	-2.6	-0.2
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.1	-0.7	-0.7	-1.0	-0.2	-0.4	0.1	-0.8	-0.1
Fractured/broken bones in last 5 years	0.5	0.6	2.1	-0.9	-0.5	-1.0	-0.5	-0.4	0.5	-0.1	1.4
Age started oral contraceptive pill	0.6	0.7	3.3	-1.1	-0.4	-0.1	-0.8	-1.8	0.2	0.2	-0.5
Diastolic blood pressure, automated reading	1.1	3.5	9.2	-3.0	1.9	2.0	2.3	-0.4	-0.7	-0.5	2.1
Ever depressed for a whole week	0.8	0.9	2.3	-0.1	-1.1	-1.1	-1.5	-0.2	-1.1	0.1	1.2
Unable to work because of sickness or disability	0.4	0.5	1.1	-0.5	0.6	0.6	-0.8	-0.8	-0.9	-1.0	0.1
Commuting to job workplace: Cycle	0.9	1.1	2.6	0.0	-1.3	-1.1	-1.6	0.0	-0.6	-1.4	-1.0
Myopia	1.4	2.1	5.2	-1.9	0.7	1.0	1.8	-2.3	0.9	-0.2	-1.5
Vascular/heart problems diagnosed by doctor	0.6	1.5	5.9	2.4	-0.2	-0.4	0.1	2.1	-0.7	0.8	-0.6
Cholesterol lowering medication	0.4	0.6	2.4	0.5	-0.2	-0.1	1.5	0.4	-0.6	-1.3	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	3.9	1.7	-0.1	0.2	-0.3	1.1	-0.9	-2.0	0.4
Pain experienced in last month	0.8	1.4	3.9	-1.4	0.2	0.4	2.0	-0.5	1.0	0.1	1.9
Supplements: Calcium	0.3	0.3	1.7	0.5	0.4	-0.1	0.0	0.6	-0.4	-0.4	-1.3
Basal cell carcinoma (self-reported)	0.6	0.7	1.6	-0.1	-0.9	-0.9	-1.0	-0.3	1.3	0.2	1.2
Heart attack/myocardial infarction (self-reported)	1.7	2.2	4.3	1.2	-1.4	-1.0	-2.0	1.5	-2.1	-1.3	0.9
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.7	0.0	-0.0	-0.1	0.5	-0.1	-1.1	-0.7	-1.3
Heart disease (siblings)	0.8	1.0	2.2	-0.6	1.3	1.1	1.5	0.2	-1.5	-0.2	0.5
Alcohol drinker status: Previous	0.9	1.1	2.0	-1.4	1.4	1.1	-0.4	-0.5	0.9	-0.3	-1.4
Pack years of smoking	0.3	0.4	1.2	-0.4	-0.6	-0.7	-1.1	0.2	0.2	-0.6	-0.7
Impedance of whole body	1.6	8.4	15.1	-2.9	-3.4	-3.2	-2.3	-3.9	2.8	2.8	0.7
Leg fat mass (left)	1.2	4.6	12.3	1.6	3.5	2.9	3.3	0.6	-1.2	-0.9	0.3
Arm predicted mass (left)	0.8	4.2	8.9	3.0	2.2	2.1	1.9	2.1	-1.8	-2.1	-0.0