Hub : Genes

PXMP2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1530	0.0400	2.8e-11	0.081	0.095	0.084	0.095	0.091	4.6e-10	1.3e-11	2.0e-10	1.3e-11	3.7e-11
2	GTEx	Brain Nucleus accumbens basal ganglia	0.3400	0.1070	3.8e-03	0.069	NA	0.043	NA	0.044	6.4e-03	NA	2.7e-02	NA	2.5e-02
3	GTEx	Cells EBV-transformed lymphocytes	0.1220	0.0610	9.3e-03	0.012	NA	-0.004	NA	-0.007	1.3e-01	NA	4.7e-01	NA	6.2e-01
4	GTEx	Cells Transformed fibroblasts	0.0980	0.0380	5.0e-04	0.029	NA	0.035	NA	0.031	3.0e-03	NA	1.2e-03	NA	2.0e-03
5	GTEx	Esophagus Muscularis	0.1150	0.0490	4.4e-03	0.012	NA	-0.005	NA	-0.001	6.1e-02	NA	8.6e-01	NA	3.9e-01
6	GTEx	Heart Left Ventricle	0.1397	0.0677	9.2e-04	0.025	NA	-0.001	NA	0.039	1.6e-02	NA	3.9e-01	NA	3.7e-03
7	GTEx	Nerve Tibial	0.0960	0.0416	2.9e-03	0.090	NA	0.048	NA	0.073	6.8e-07	NA	2.5e-04	NA	7.6e-06
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0400	0.0244	5.3e-04	0.023	0.032	0.027	NA	0.025	1.1e-03	1.5e-04	4.4e-04	NA	7.0e-04
9	TCGA	Brain Lower Grade Glioma	0.0664	0.0338	3.1e-03	0.035	0.022	0.025	NA	0.031	6.6e-05	1.2e-03	6.9e-04	NA	1.7e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.2	0.2	1.1	0.1	0.4	0.4	1.0	0.4	0.1	0.6	0.4	0.3
Bipolar Disorder or Schizophrenia	0.8	2.0	4.3	1.6	0.8	2.1	2.1	1.6	-1.2	0.5	-1.3	0.7
Depressed Affect (Nagel 2018)	0.4	0.9	2.2	1.5	0.4	1.2	0.2	1.3	-1.0	0.3	-1.2	0.5
Depression (Nagel 2018)	0.5	0.8	2.8	0.8	0.0	1.7	0.3	1.4	-1.1	-0.2	-0.5	-0.3
Intelligence (Savage-Jansen 2018)	0.6	1.9	5.8	-0.7	1.7	-0.1	0.0	-1.2	2.4	1.4	1.5	1.5
Neuroticism (Nagel 2018)	0.5	1.2	2.6	1.3	0.8	1.4	0.9	1.6	-0.5	0.9	-1.1	0.9
Schizophrenia (2018)	1.3	2.6	5.7	2.0	0.7	2.4	1.9	1.8	-1.6	0.2	-1.9	0.7
Schizophrenia vs Biploar Disorder	0.4	0.5	2.0	1.4	0.5	0.2	0.6	0.9	-0.1	0.9	-0.6	0.6
Worry (Nagel 2018)	0.7	1.4	4.8	0.4	0.5	1.9	1.0	2.2	-1.1	0.7	-1.1	0.4
Alzheimer’s Disease (in mother)	0.2	0.3	0.8	-0.6	-0.4	-0.3	0.9	0.8	0.1	-0.5	0.4	-0.4
Alzheimer’s Disease (in father)	0.8	0.9	1.9	1.0	-1.4	-0.3	-0.2	0.7	-1.2	-0.8	-1.0	-1.3
Alzheimer’s Disease (including proxy)	0.4	0.6	1.9	-0.1	-1.1	-0.3	0.4	1.4	-0.8	-0.7	-0.2	-1.2
Crohns Disease (2017)	0.3	0.7	2.8	0.2	-0.8	0.6	-0.5	1.7	-0.7	-0.5	-0.9	-0.7
Irritable Bowel Disease (IBD)	0.1	0.2	0.9	-0.3	-0.3	0.0	-1.0	-0.5	0.9	-0.1	0.2	-0.1
Ulcerative Colitis (UC)	0.6	1.2	3.7	-0.8	0.3	-0.7	-0.8	-1.7	1.9	0.4	1.3	0.6
Major Depression (MDD)	0.3	0.4	1.3	0.5	0.2	0.7	0.9	1.1	-0.6	0.0	-0.4	0.1
Reaction Time	0.9	1.7	7.8	0.0	-1.5	-0.8	-2.8	-1.7	0.4	-0.8	-0.0	-1.0
Verbal and Numeric Reasoning (VNR)	0.7	1.7	5.0	-0.5	1.6	-0.3	0.3	-0.7	2.2	1.4	1.5	1.5
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	2.6	3.5	12.1	2.6	1.3	0.3	3.5	1.2	-1.6	1.3	-1.9	1.4
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	1.2	1.7	5.3	0.8	0.4	-1.5	-1.4	-0.9	2.3	0.6	1.8	0.6
Bipolar Disorder (2011)	0.0	0.0	0.3	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.5	-0.2
Body Mass Index (BMI) (2010)	0.6	0.8	3.2	0.5	-0.4	0.2	0.4	0.4	-1.6	-0.5	-1.8	-0.3
Coronary Artery Disease (CAD)	0.3	0.3	1.4	-0.5	0.6	0.2	0.5	1.2	-0.0	0.4	0.2	0.4
Crohns Disease (2012)	0.1	0.1	0.8	-0.9	-0.1	-0.4	-0.3	0.0	-0.0	0.0	0.2	-0.2
Mean Putamen Volume	0.3	0.3	0.9	0.1	-0.6	-0.5	-0.4	-0.6	0.6	0.3	0.9	-0.6
Fasting Glucose	3.2	3.8	10.9	-1.3	-3.2	0.2	-1.9	-0.2	-1.2	-2.6	0.1	-3.3
HbA1C	1.9	2.1	6.9	-1.6	-1.5	0.0	-2.6	-1.2	-0.8	-1.4	0.9	-1.4
HDL Cholesterol	0.1	0.1	0.5	0.4	-0.1	0.7	-0.2	0.5	-0.1	-0.3	-0.0	-0.2
LDL Cholesterol	0.3	0.5	0.9	0.7	0.9	-0.8	0.1	-0.6	0.6	1.0	0.2	0.8
Lupus	0.3	0.5	1.5	-0.5	0.2	-0.4	1.1	-0.6	1.1	-0.2	1.2	0.1
Neuroticism (2016)	1.7	2.5	4.5	1.8	1.7	1.6	1.1	2.1	-0.5	1.9	-1.4	1.4
Primary Biliary Cirrhosis	1.0	1.4	4.4	-0.9	-0.7	-1.5	-1.1	-2.1	1.0	-1.0	0.8	-0.7
Rheumatoid Arthritis	0.4	0.6	1.9	0.7	0.4	-1.0	-1.4	-1.0	0.6	0.3	0.3	0.5
Schizophrenia (2014)	0.9	1.9	3.2	1.7	1.3	1.8	1.7	1.0	-0.9	1.2	-1.2	1.3
Triglycerides	0.5	0.8	3.4	-0.9	-0.8	0.1	-1.8	-0.8	-0.6	-0.8	0.2	-1.0
Type 2 Diabetes (T2D) (2012)	0.2	0.2	1.0	-0.3	-0.3	-1.0	0.5	-0.1	0.2	-0.5	0.4	-0.5
Ulcerative Colitis	0.9	1.3	5.0	-0.6	0.3	-0.4	-1.0	-2.2	1.8	0.9	1.0	0.6
Blood Eosinophil Count	1.6	12.3	29.1	-4.5	-0.1	-5.4	-2.9	-4.3	3.9	-0.0	4.4	0.2
Blood Platelet Count	0.6	6.7	15.4	-0.6	-1.6	3.9	-2.3	2.5	-3.7	-2.5	-2.2	-2.3
Blood Red Count	0.3	2.6	8.4	-1.8	-1.1	1.7	-2.9	0.1	-1.7	-1.8	-0.7	-1.2
Blood White Count	0.0	0.3	0.6	-0.3	-0.5	-0.5	0.0	0.8	-0.8	0.1	-0.4	-0.4
Heel T-Score	0.1	1.0	2.7	0.3	1.0	-0.6	1.6	0.6	0.9	1.6	0.5	0.9
BMI	0.7	4.1	9.9	2.2	1.0	0.2	3.1	2.1	-2.1	1.8	-2.8	1.2
Height	0.3	4.9	13.5	2.6	2.8	0.2	2.0	3.7	-0.0	2.5	0.0	2.5
Waist Hip Ratio (WHR)	0.5	2.1	4.1	-1.7	-1.6	-0.6	-2.0	0.3	0.1	-2.0	1.1	-1.9
Systolic Blood Pressure	1.3	6.3	11.3	-3.4	-1.4	-3.0	-2.4	-3.2	2.6	-0.4	3.2	-1.1
Smoking Status	0.2	0.4	2.1	0.3	-0.8	-0.6	-1.5	0.5	0.1	0.2	0.3	-0.3
Allergy or Eczema	1.6	4.3	10.8	0.8	3.0	-0.8	1.6	-0.1	2.4	3.0	0.5	3.3
Cardiovascular Disease	0.2	0.6	1.3	-1.1	-1.1	-0.9	-0.4	-1.0	-0.5	-0.3	-0.1	-0.8
Hypothyroidism (self reported)	0.4	0.9	2.0	-1.0	0.3	-1.4	-0.3	-1.2	1.3	0.6	1.0	0.6
Respiratory disease	0.4	0.8	2.2	-1.1	-0.2	-1.0	-0.3	-1.4	1.5	-0.2	0.9	-0.2
Type 2 Diabetes (T2D) (2018)	0.5	0.8	2.2	0.2	-0.2	0.7	0.9	1.4	-1.5	-0.0	-1.4	-0.3
Lung FEV1/FVC ratio	0.4	1.8	4.5	0.6	1.0	-1.4	2.1	0.4	1.5	1.2	1.9	0.9
Lung FVC	0.4	2.0	6.6	-1.8	-1.1	0.7	-2.6	-1.2	-0.4	-1.7	0.1	-1.5
Neuroticism	0.9	2.1	5.0	1.4	0.5	1.7	2.1	2.2	-1.1	1.1	-1.4	0.6
Chronotype (morning person)	0.6	1.3	2.7	-1.5	-0.8	-0.9	-1.2	-1.6	0.8	-0.7	1.5	-0.9
Hair Pigment	0.1	1.8	4.4	0.7	1.9	-0.5	1.6	0.2	0.4	2.1	-0.4	2.0
Tanning	0.1	0.8	2.1	-0.4	-1.3	0.7	0.0	0.5	-1.5	-0.7	-0.9	-1.1
Hand grip strength (left)	2.2	5.8	16.8	-0.3	-4.0	1.4	-2.1	0.7	-1.4	-3.2	-0.3	-4.1
Number of treatments/medications taken	0.8	1.4	6.2	-2.5	-1.0	-1.4	-0.4	-1.1	-0.0	-0.8	1.0	-0.8
Average weekly spirits intake	1.4	1.7	4.5	-0.1	2.0	-0.7	0.1	-0.5	1.5	1.9	0.9	2.1
Sensitivity / hurt feelings	3.2	5.4	13.3	2.8	2.9	0.0	2.1	1.4	0.5	3.6	-1.5	3.2
Frequency of depressed mood in last 2 weeks	1.2	1.7	5.1	0.9	-0.8	2.3	-0.2	1.7	-1.8	-0.7	-1.2	-0.9
Hearing difficulty/problems: Yes	0.2	0.3	0.6	-0.7	0.4	-0.3	0.8	-0.2	0.6	0.7	0.7	0.3
Relative age of first facial hair	0.4	0.8	2.3	-0.6	-0.4	-1.1	-0.4	-0.7	1.4	-0.2	1.5	-0.4
Other serious medical condition/disability diagnosed by doctor	2.1	2.7	9.0	-1.5	0.8	-3.0	-0.3	-1.1	1.8	1.3	2.2	1.1
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.4	-0.5	-0.1	0.6	0.6	1.6	-1.1	-0.2	-0.5	-0.3
Ever had hysterectomy (womb removed)	0.1	0.1	0.4	-0.6	-0.0	-0.6	-0.5	-0.4	0.1	0.3	0.1	0.0
Systolic blood pressure, automated reading	0.9	2.7	7.2	-2.3	-1.0	-2.0	-0.9	-1.6	1.8	-0.1	2.7	-0.7
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	6.2	0.5	1.2	0.9	2.5	1.0	-0.9	0.9	-0.8	0.9
Angina	1.9	2.5	5.4	1.5	0.9	0.9	1.9	1.7	-2.0	1.4	-2.3	1.0
Medication for hormone replacement therapy	1.6	1.8	4.4	2.1	1.3	1.3	0.5	0.9	-0.9	1.2	-1.9	1.3
Vitamin and mineral supplements	0.1	0.1	0.4	0.3	-0.0	-0.3	-0.0	-0.4	-0.5	-0.6	-0.0	-0.2
Supplements: Zinc	5.1	5.5	12.8	1.2	3.4	-2.0	2.7	0.1	1.5	3.2	-0.0	3.6
Medication: Co-codamol	0.2	0.3	0.8	-0.8	-0.5	-0.9	0.7	-0.4	-0.2	-0.1	0.2	-0.3
Medication: Metformin	0.8	1.1	1.8	1.0	1.4	-0.5	1.1	0.9	-0.9	1.2	-1.1	1.1
Diabetes (father)	0.2	0.2	0.8	-0.6	0.5	-0.9	-0.3	-0.3	0.2	0.4	0.5	0.3
Diabetes (mother)	0.5	0.6	3.0	0.5	0.7	0.6	1.7	0.5	0.2	0.7	0.3	0.7
Severe depression (siblings)	0.7	0.8	2.2	-1.4	0.3	-0.7	0.2	-1.0	1.0	-0.3	1.5	-0.1
Pack years adult smoking proportion	0.2	0.3	0.9	-0.6	0.3	-0.3	0.2	-0.3	1.0	1.0	0.4	0.4
Impedance of leg (right)	1.0	5.0	15.0	-2.9	-1.3	-0.3	-3.9	-0.3	1.1	-2.7	2.9	-1.7
Leg fat-free mass (left)	1.4	7.3	15.6	4.0	1.4	1.2	3.8	2.8	-2.0	2.6	-3.3	1.6
Trunk fat percentage	0.1	0.3	1.5	-0.0	0.3	-0.8	0.7	1.2	-0.3	0.1	0.0	0.4
Hand grip strength (right)	2.3	6.4	16.6	0.2	-3.9	1.9	-2.0	2.1	-2.1	-3.0	-0.9	-4.1
Townsend deprivation index at recruitment	0.1	0.2	0.8	-0.4	-0.3	-0.0	-0.5	-0.9	0.3	0.3	-0.3	-0.0
Current tobacco smoking	0.4	0.7	1.9	0.3	-1.3	0.3	-1.4	1.0	-0.6	0.2	-0.4	-0.9
Average weekly fortified wine intake	0.8	0.9	2.5	-1.2	-0.9	0.0	-0.2	-0.3	0.9	-1.2	1.6	-1.0
Maternal smoking around birth	0.0	0.1	0.3	0.2	0.1	-0.5	-0.4	0.0	-0.1	-0.1	-0.1	-0.1
Fed-up feelings	0.3	0.5	1.3	1.1	0.3	0.6	0.3	1.1	-0.9	0.1	-0.7	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.7	1.2	-0.1	1.3	0.2	1.1	-1.0	0.0	-0.8	-0.2
Relative age voice broke	0.8	1.2	3.8	-0.6	-0.7	-1.3	-1.9	-0.1	0.9	-1.2	1.5	-0.7
Taking other prescription medications	0.9	1.4	4.4	-2.1	-1.2	-1.1	-0.2	-1.6	-0.1	-1.0	0.8	-1.0
Age when periods started (menarche)	1.7	4.1	12.7	-0.9	-0.2	-2.7	-1.2	-1.4	3.5	0.4	3.6	-0.2
Bilateral oophorectomy (both ovaries removed)	0.7	0.9	2.3	-1.1	0.6	-0.9	-0.9	-1.5	1.0	-0.1	0.9	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	1.6	1.2	1.2	-0.8	0.0	-0.1	0.5	1.1	-0.5	1.2
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	6.3	-0.2	-0.8	1.7	-1.1	2.5	-1.7	-0.6	-0.6	-0.9
Qualifications: CSEs or equivalent	0.9	1.2	3.8	0.6	-0.1	0.9	-1.8	-0.3	-1.3	-0.7	-1.9	-0.1
Serious illness, injury or assault to yourself	0.5	0.6	3.4	-0.6	0.6	-1.8	0.5	-0.1	0.2	0.5	0.1	0.7
High blood pressure	0.6	1.8	4.2	-1.7	-2.0	-1.6	-0.2	-0.9	-0.1	-1.1	1.0	-1.8
Hayfever, allergic rhinitis or eczema	1.7	3.6	9.9	0.7	2.8	-0.6	1.4	0.1	1.7	3.0	-0.0	3.1
Multivitamins +/- minerals	0.6	0.7	1.7	0.9	0.9	-0.8	-0.0	0.0	1.2	1.3	0.2	1.1
Stomach or abdominal pain in last month	1.3	1.6	3.8	-0.1	-1.5	1.2	-0.9	0.3	-1.9	-1.7	-1.2	-1.4
Supplements: Glucosamine	0.1	0.1	0.4	0.0	0.1	0.4	-0.7	-0.4	0.5	-0.2	0.4	-0.1
Diverticular disease/diverticulitis (self-reported)	1.3	1.6	4.2	-1.7	-1.2	-1.1	-0.8	-2.0	0.8	-1.1	1.0	-1.1
Medication: Atenolol	1.3	1.6	3.2	-1.4	-1.7	-0.5	-1.8	-0.8	-0.2	-1.5	0.1	-1.7
Medication: Levothyroxine sodium	1.1	1.9	5.6	-1.1	0.7	-2.4	0.5	-1.3	1.7	1.0	1.7	0.9
Sitting height	0.1	0.8	2.2	1.2	1.0	0.1	1.5	0.2	0.5	1.1	-0.3	1.0
Chronic bronchitis/emphysema (father)	0.1	0.2	0.4	0.6	0.1	-0.0	-0.6	-0.4	0.6	0.2	0.3	0.2
High blood pressure (mother)	0.6	0.8	2.2	0.2	-0.3	0.0	1.5	1.4	-1.3	0.2	-1.2	-0.3
Body mass index (BMI)	0.7	3.0	6.8	1.8	-0.1	1.1	2.1	2.1	-2.5	0.3	-2.6	0.0
Impedance of leg (left)	1.4	6.6	21.8	-3.4	-1.4	-0.3	-4.7	-0.8	1.4	-2.9	3.1	-1.8
Leg predicted mass (left)	1.4	7.5	15.9	4.0	1.5	1.2	3.9	2.8	-2.0	2.6	-3.3	1.7
Trunk fat mass	0.3	1.5	4.3	1.3	0.6	0.0	1.8	2.1	-1.2	0.7	-1.1	0.7
Waist circumference	1.0	3.8	7.5	2.2	0.4	1.1	2.4	2.7	-2.6	0.6	-2.7	0.4
Number of incorrect matches in round	0.9	1.5	3.5	1.9	0.8	0.4	1.0	0.9	-0.7	1.8	-1.7	1.1
Past tobacco smoking	0.6	1.2	3.8	-1.4	-0.7	-0.0	-1.1	-1.9	0.7	-1.0	0.8	-0.9
Alcohol usually taken with meals	0.4	0.6	2.1	-0.7	0.3	-0.9	-0.2	-1.5	1.1	0.1	0.6	0.3
Nervous feelings	0.1	0.1	0.4	-0.6	0.3	-0.2	0.0	0.1	0.4	0.1	0.6	0.1
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	2.7	0.8	-0.8	1.6	0.8	1.6	-1.6	-1.0	-1.0	-1.0
Hearing difficulty/problems with background noise	0.7	1.2	4.4	0.3	1.0	1.2	2.1	1.2	-0.9	0.6	-0.6	0.8
Hair/balding pattern: Pattern 2	2.3	2.9	9.8	-1.1	-3.1	0.1	-1.6	0.6	-0.7	-1.9	0.3	-2.9
Had menopause	1.4	1.7	4.3	-2.1	0.4	-2.0	-0.2	-0.9	1.2	-0.3	2.1	0.2
Had other major operations	1.1	1.3	3.0	1.4	1.5	-0.6	1.7	0.2	-0.9	0.9	-0.7	1.5
Forced vital capacity (FVC)	0.2	0.7	2.3	0.6	-0.1	1.3	-1.5	0.6	-0.6	-0.4	-0.7	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.3	3.8	1.2	1.3	-0.9	0.8	0.1	0.9	2.0	-0.4	1.5
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.3	0.3	-0.6	0.3	-0.3	-0.0	0.4	0.2	0.5	-0.5
Qualifications: None of the above	0.4	0.9	2.3	0.7	-0.1	0.2	1.4	1.5	-1.3	0.2	-1.3	-0.0
Financial difficulties in last 2 years	0.5	0.7	2.6	-0.3	-1.6	0.8	0.1	-0.1	-0.5	-0.1	-0.9	-1.2
Mouth/teeth dental problems	1.7	2.5	8.4	2.9	1.0	0.6	0.8	2.4	-1.6	0.8	-1.5	1.1
Heart attack	1.6	2.1	6.4	1.5	-0.2	1.6	1.2	2.5	-1.7	0.7	-1.7	-0.2
Allergy	0.3	0.7	1.7	-0.6	-1.2	0.1	-0.8	0.1	-1.0	-1.3	0.1	-1.3
Pain all over the body in last month	0.2	0.3	1.1	1.0	0.3	-0.5	-0.1	-0.4	-0.6	0.1	-0.5	0.3
Diabetes (self-reported)	0.7	1.1	3.8	0.9	0.6	-0.1	1.9	1.1	-1.0	0.9	-1.2	0.5
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	3.7	0.4	1.5	-0.2	0.7	0.6	1.3	1.9	0.4	1.9
Medication: Ramipril	1.6	2.0	7.1	-1.1	0.8	-2.7	0.9	-1.3	1.7	0.8	1.4	1.0
Medication: Simvastatin	0.2	0.3	1.2	-0.2	0.4	0.3	0.4	0.3	-0.2	1.1	-0.8	0.6
Fluid intelligence score	1.3	2.7	8.8	-1.0	1.5	-1.7	-0.3	-0.9	3.0	1.3	2.1	1.5
Illnesses of siblings	1.0	1.5	4.8	0.5	-0.8	2.2	-0.5	0.8	-1.5	-1.2	-1.5	-0.9
Neuroticism score	1.0	2.1	4.0	1.7	0.8	1.7	1.9	2.0	-1.1	1.2	-1.4	0.9
Weight	0.8	3.9	7.4	2.5	0.7	1.1	2.5	2.7	-2.2	1.2	-2.5	0.8
Impedance of arm (right)	1.6	7.6	17.1	-3.4	0.6	-3.2	-2.7	-2.6	3.7	-0.6	4.1	0.5
Arm fat percentage (right)	0.2	0.7	1.9	0.5	0.3	-0.1	1.4	1.2	-1.2	0.1	-1.1	0.3
Trunk fat-free mass	1.3	7.2	17.4	4.2	1.0	2.2	3.0	3.1	-2.6	2.0	-3.4	1.0
Hip circumference	0.9	3.8	10.2	2.2	1.1	0.9	3.2	1.9	-1.8	1.4	-2.5	1.2
Time employed in main current job	3.2	3.7	8.6	-2.9	-1.5	-1.5	-0.6	-2.5	1.4	-1.6	2.5	-1.6
Alcohol intake versus 10 years previously	0.2	0.3	1.0	0.3	-0.1	0.5	-1.0	0.3	-0.5	0.1	-0.8	0.1
Father’s age at death	0.4	0.5	2.5	0.9	0.2	1.6	-0.6	0.4	-0.3	0.0	-0.7	0.1
Worrier / anxious feelings	0.3	0.5	1.2	0.8	1.0	1.1	0.4	0.3	0.6	0.7	-0.0	1.0
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	3.5	1.3	-0.1	1.7	1.5	1.9	-1.8	-0.1	-1.8	-0.3
Falls in the last year	0.5	0.7	4.0	-0.5	0.5	-0.3	2.0	-0.9	0.1	0.2	0.9	0.1
Hair/balding pattern: Pattern 3	3.4	5.1	13.3	1.5	3.6	-1.2	1.9	-1.0	1.4	3.1	-0.2	3.6
Number of live births	0.3	0.5	2.6	-0.2	0.2	0.0	1.6	0.2	-0.9	-0.2	-0.6	0.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	2.6	0.8	-0.1	1.6	-1.1	0.8	-0.8	-0.5	-0.6	-0.4
Pulse rate	0.6	1.1	1.8	1.3	1.1	1.1	0.9	-0.9	-0.0	1.1	-1.2	1.1
Happiness	1.4	1.6	4.1	-1.6	-1.1	-1.5	-0.3	-1.3	1.3	-0.5	2.0	-1.0
Noisy workplace	1.2	1.5	4.7	1.2	-0.7	1.5	0.1	0.9	-1.9	0.0	-2.2	-0.6
Qualifications: A levels/AS levels or equivalent	0.6	1.4	4.5	-1.2	0.2	-1.4	-1.1	-0.9	1.5	-0.7	2.1	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.3	0.6	0.4	-0.4	0.1	0.5	0.1	0.6	-0.2	0.6
Mouth/teeth dental problems: Dentures	0.6	1.1	3.2	-1.8	-0.9	-0.7	-0.1	-1.6	0.5	-1.0	0.6	-0.9
Asthma	0.1	0.2	0.3	-0.1	0.6	-0.2	-0.2	0.2	0.6	0.5	-0.1	0.5
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.2	0.2	-0.4	1.4	0.1	0.9	-1.5	-1.0	-0.7	-0.5
Medication: Cholesterol lowering	1.4	2.1	4.1	0.1	1.8	-1.5	1.9	0.6	1.1	2.0	0.9	1.8
Depression (self-reported)	1.1	1.3	3.9	0.4	-1.2	2.0	-1.3	0.5	-1.0	-0.8	-1.0	-1.2
Medication: Lansoprazole	0.5	0.5	1.6	-0.1	-0.5	0.9	-0.2	0.6	-1.3	-0.5	-0.9	-0.7
Prospective memory result	1.8	2.2	6.4	-2.0	-2.5	-0.2	-0.9	-0.8	-0.2	-1.9	0.5	-2.2
Lung cancer (father)	0.5	0.6	2.1	-0.0	0.7	0.8	1.1	0.5	0.0	1.5	-0.4	0.9
Illnesses of mother	0.9	1.1	2.0	1.4	1.2	-0.2	-1.3	-1.0	1.2	1.0	-0.1	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.6	2.3	0.1	-0.2	1.5	-0.7	0.6	-0.9	-0.6	-0.8	-0.6
Pulse wave Arterial Stiffness index	2.2	2.6	4.5	1.3	1.3	1.2	0.7	2.0	-1.9	1.8	-2.1	1.5
Impedance of arm (left)	1.8	8.6	20.7	-3.2	0.9	-3.5	-2.4	-2.8	4.3	0.1	4.5	0.9
Arm fat mass (right)	0.6	2.4	4.7	1.7	0.4	0.8	2.0	2.2	-2.1	0.6	-2.1	0.5
Trunk predicted mass	1.2	6.8	16.9	4.1	1.0	2.2	2.8	3.0	-2.5	1.9	-3.3	1.0
Standing height	0.2	1.9	4.2	1.8	1.6	0.4	1.2	2.0	0.2	1.8	-0.1	1.5
Length of working week for main job	2.4	2.7	6.2	-1.2	-1.8	-0.9	-2.0	-2.5	1.3	-1.2	1.6	-1.6
Exposure to tobacco smoke at home	0.7	0.8	2.7	0.2	-0.8	-1.2	-0.5	-1.6	0.7	-0.6	0.7	-0.7
Breastfed as a baby	0.2	0.3	1.8	0.0	-0.1	-0.7	-1.3	-0.0	0.2	-0.2	0.5	-0.2
Tense / ‘highly strung’	0.5	0.8	2.0	1.0	-0.3	0.8	0.5	1.4	-1.3	0.1	-1.3	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.8	4.0	2.0	1.4	1.7	0.6	1.6	-0.6	1.1	-1.1	1.3
Hair/balding pattern: Pattern 4	0.1	0.4	0.9	0.2	0.8	-0.4	-0.1	-0.2	0.7	0.9	0.2	0.9
Birth weight of first child	1.0	1.8	4.4	0.3	1.1	-1.6	1.3	1.2	1.5	1.2	2.1	1.1
Peak expiratory flow (PEF)	0.1	0.1	0.6	-0.2	0.8	0.5	-0.4	-0.2	0.1	-0.1	0.2	0.4
Pulse wave reflection index	1.1	1.3	5.4	0.4	0.6	0.5	0.8	2.3	-1.3	1.2	-1.2	0.7
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.6	0.6	-0.8	-0.0	0.3	-0.0	-0.3	-0.4	-0.4	-0.6
Loud music exposure frequency	1.8	1.9	3.9	1.2	-1.3	1.6	0.3	0.7	-1.8	-1.5	-2.0	-1.4
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	2.8	-0.3	1.7	-0.9	-1.5	-0.8	1.7	0.9	1.3	1.6
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.3	-1.4	-0.8	-0.8	0.1	-1.1	1.5	-0.0	1.0	-0.6
Blood clot in the leg (DVT)	0.2	0.2	1.7	-0.1	0.1	0.4	1.3	-0.3	-0.3	0.3	-0.3	-0.0
Medication: Paracetamol	1.8	3.0	7.2	-1.1	-2.0	1.1	-0.5	-0.0	-2.7	-2.6	-1.5	-2.1
Headache pain in last month	2.2	3.8	8.9	1.7	0.1	2.3	1.3	2.6	-3.0	-0.2	-2.9	0.0
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	3.6	0.6	-0.1	1.9	-0.7	0.3	-0.3	-0.6	-0.6	-0.4
Glaucoma (self-reported)	0.2	0.3	0.6	-0.8	0.5	-0.6	0.3	-0.2	0.4	0.8	0.3	0.4
Gout (self-reported)	1.1	1.5	3.8	-1.9	-0.5	-1.0	-1.8	-0.9	1.4	-0.1	1.4	-0.2
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	2.8	-0.6	1.2	-1.6	0.1	-0.7	1.4	1.7	1.1	1.6
Medication: Amlodipine	0.9	1.3	5.3	-2.3	-0.7	-1.2	-0.3	-0.4	0.4	-1.3	1.4	-0.8
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.5	0.1	-0.1	-0.5	-0.1	-0.6	0.7	0.3	0.0	-0.1
Birth weight	0.8	1.8	4.9	-1.3	0.3	-2.2	-1.0	-1.6	1.8	0.3	1.6	0.5
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.7	-0.7	-0.2	-0.3	-0.4	-0.6	-0.6	-0.8	0.3	-0.5
High blood pressure (siblings)	0.5	0.8	3.2	0.1	0.3	-1.8	1.2	-0.5	0.4	1.1	0.3	0.6
Forced vital capacity (FVC), Best measure	0.2	0.8	3.0	0.0	-0.5	1.7	-0.8	0.7	-0.9	-0.6	-1.0	-0.7
Body fat percentage	0.2	0.7	3.0	0.4	0.2	0.0	1.1	1.7	-1.2	-0.1	-0.8	0.2
Leg fat percentage (right)	0.7	2.4	6.8	1.0	-0.8	1.3	0.9	2.2	-2.6	-0.9	-2.0	-0.8
Arm fat-free mass (right)	1.4	7.0	14.2	3.8	0.6	2.5	2.7	3.4	-2.8	1.7	-3.5	0.7
Exposure to tobacco smoke outside home	1.3	1.7	4.3	-1.5	-0.6	-0.9	-0.7	-2.1	1.9	0.1	1.8	-0.4
Comparative body size at age 10	0.7	1.9	5.0	1.9	0.7	1.1	-0.2	1.1	-2.2	0.2	-2.2	0.6
Number of full brothers	1.9	2.4	5.9	1.1	-0.1	1.8	0.6	2.4	-2.3	0.3	-2.4	-0.2
Worry too long after embarrassment	1.0	1.7	4.3	-0.8	0.2	-1.3	1.5	-2.1	2.0	0.1	1.6	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.4	1.6	0.6	0.3	1.0	-0.5	0.9	0.6	-0.2	0.7
Wheeze or whistling in the chest in last year	0.6	1.1	2.2	-1.0	-1.5	-0.8	-1.1	-1.0	0.8	-0.9	0.7	-1.4
Number of children fathered	1.0	1.1	4.0	0.7	-0.6	1.0	0.3	1.6	-1.2	-0.1	-2.0	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	2.5	0.4	0.3	0.6	-1.6	0.6	0.1	-0.2	-0.3	0.2
Age at first live birth	0.5	1.0	3.7	-0.6	-0.8	-0.9	0.1	-0.7	1.4	-0.5	1.9	-0.8
Pulse wave peak to peak time	1.6	1.9	3.6	-1.1	-1.1	-1.0	-0.5	-1.6	1.7	-1.5	1.9	-1.3
Health satisfaction	0.2	0.3	0.7	-0.3	-0.4	0.1	0.8	-0.1	-0.7	-0.7	0.3	-0.6
Shortness of breath walking on level ground	0.6	0.7	2.7	-0.1	-0.0	0.7	1.6	0.4	-1.0	0.8	-1.1	0.0
Qualifications: College or University degree	1.0	3.0	8.8	-0.8	0.5	-2.4	0.3	-2.0	3.0	1.1	2.5	0.7
Eye problems/disorders: None of the above	2.3	2.6	11.7	-1.1	-1.7	-0.0	-3.4	-0.8	1.0	-1.4	1.3	-1.6
Mouth/teeth dental problems: Loose teeth	0.4	0.4	3.5	-0.4	-0.1	0.4	1.9	0.0	0.1	0.2	-0.0	-0.1
Emphysema/chronic bronchitis	0.2	0.2	0.6	0.8	-0.6	-0.1	0.6	-0.3	0.3	-0.3	0.3	-0.7
Medication for pain relief, constipation, heartburn	1.3	2.2	6.1	1.3	1.8	-0.4	-0.0	-0.3	2.5	2.0	1.1	1.8
Neck or shoulder pain in last month	1.2	1.7	4.2	-2.1	-2.0	0.1	1.1	-1.0	-0.5	-1.1	0.7	-1.8
Medication: Blood pressure	0.3	0.4	1.1	-0.6	-1.0	-1.0	1.0	-0.1	-0.5	-0.1	-0.1	-0.6
Angina (self-reported)	2.1	2.8	5.4	1.5	1.0	1.1	2.0	2.0	-1.9	1.6	-2.3	1.1
Migraine (self-reported)	2.9	3.6	6.5	1.7	-1.2	2.5	2.3	2.5	-2.1	0.4	-2.0	-0.9
Medication: Ibuprofen	0.6	0.7	2.5	0.1	0.1	1.3	-0.4	1.0	-1.6	-0.7	-1.0	-0.1
Medication: Allopurinol	0.4	0.5	1.5	-0.9	-0.1	-0.8	-1.2	-0.6	1.0	0.3	0.7	0.2
Medication: Omeprazole	1.0	1.2	5.0	-2.2	-0.5	-0.6	-0.3	-1.4	1.1	-0.3	1.4	-0.4
Medication: Seretide 50 evohaler	0.4	0.5	3.3	-1.8	-0.1	0.1	0.5	-0.3	0.4	-0.1	0.7	-0.3
Mean time to correctly identify matches	0.9	1.8	3.9	-1.1	-1.9	-0.6	-2.0	-1.8	0.4	-1.0	0.6	-1.5
Heart disease (mother)	0.9	1.1	3.0	0.0	-0.3	1.2	1.7	1.6	-1.3	0.4	-1.0	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.6	-0.1	0.3	0.3	-0.3	-0.0	0.3	0.7	-0.1	0.4
Whole body fat mass	0.6	2.4	6.5	1.6	0.3	0.8	2.0	2.5	-2.0	0.4	-1.8	0.4
Leg fat mass (right)	1.1	4.2	8.9	2.1	-0.2	1.7	2.3	2.9	-3.0	-0.0	-2.8	-0.2
Arm predicted mass (right)	1.4	7.2	15.0	3.9	0.9	2.4	2.9	3.3	-2.7	1.8	-3.5	0.9
Pulse rate, automated reading	1.1	3.5	10.1	2.3	1.2	3.2	1.9	0.7	-1.3	1.6	-2.3	1.3
Alcohol intake frequency.	0.3	0.7	2.7	-0.2	0.0	1.6	0.2	0.7	-1.2	-0.6	-1.2	-0.2
Comparative height size at age 10	0.6	3.2	8.5	-0.4	0.6	2.4	0.9	2.9	-2.9	0.5	-2.1	0.2
Number of full sisters	0.7	0.8	2.0	0.1	-1.0	1.2	-0.8	0.8	-0.6	-1.4	0.0	-1.3
Suffer from ‘nerves’	0.4	0.7	2.6	0.3	0.4	1.6	0.5	1.0	-0.8	0.4	-1.1	0.3
Overall health rating	0.3	0.7	1.2	-1.0	-1.0	-0.3	1.0	-0.5	-1.1	-0.9	-0.0	-1.1
Chest pain or discomfort	2.9	4.2	8.1	2.1	1.2	1.8	2.3	2.4	-2.6	1.4	-2.9	1.2
Had major operations	0.4	0.5	1.3	0.0	0.7	0.4	1.1	0.9	0.0	0.9	-0.6	0.7
Age at last live birth	0.7	1.1	2.6	-1.1	-1.0	-0.9	0.5	-0.7	1.6	-0.2	1.6	-0.8
Family relationship satisfaction	2.1	2.6	6.2	1.3	2.5	-0.8	2.0	0.6	0.6	2.1	-0.3	2.3
Leg pain on walking	0.2	0.3	1.2	-0.4	0.3	-0.5	1.1	-0.2	0.0	0.9	-0.3	0.4
Qualifications: NVQ or HND or HNC or equivalent	2.1	2.5	6.7	1.7	0.5	2.6	0.1	1.6	-2.3	0.1	-2.2	0.3
Commuting to job workplace: Car/motor vehicle	0.5	0.5	2.8	-0.0	-0.7	0.4	0.7	1.7	-0.6	0.1	-0.3	-0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.8	0.8	0.7	0.5	0.9	-0.5	0.3	0.5	0.1	0.7
Medication: Aspirin	0.4	0.5	0.9	-0.8	-1.0	-0.9	-0.3	-0.0	-0.5	-0.8	0.4	-0.9
Supplements: Vitamin C	0.2	0.2	0.5	-0.3	-0.5	0.1	-0.6	0.5	-0.7	0.1	-0.7	-0.2
Knee pain experienced in last month	1.5	2.4	7.2	-0.2	-0.9	2.7	0.0	1.6	-2.2	-1.3	-1.5	-1.4
Hypertension (Self-reported)	0.6	1.7	3.7	-1.8	-1.9	-1.4	-0.1	-1.1	-0.1	-1.0	0.7	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	2.4	-1.4	-1.4	0.4	-1.4	-0.3	-1.0	-1.2	-0.6	-1.6
Illnesses of father: Heart disease	0.5	0.7	1.3	-0.5	1.1	-1.0	0.7	-1.0	0.2	0.7	-0.2	1.2
Illnesses of siblings: Diabetes	1.0	1.3	1.8	-1.2	-1.1	-1.3	-1.0	-1.2	0.3	-1.2	1.2	-1.3
Smoking status: Previous	0.7	1.1	2.9	0.8	1.2	-0.2	1.7	1.3	-0.6	0.8	-0.7	1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	4.2	0.8	2.0	-0.3	0.7	-0.7	0.9	1.9	-0.1	2.0
Whole body fat-free mass	1.3	7.6	17.0	4.1	1.1	2.0	3.3	3.1	-2.5	2.2	-3.5	1.2
Leg fat-free mass (right)	1.2	6.6	13.9	3.7	1.4	1.3	3.6	2.4	-1.9	2.5	-3.3	1.6
Arm fat percentage (left)	0.2	0.8	2.7	0.7	0.5	-0.4	1.6	1.0	-0.9	0.5	-0.9	0.6
Average weekly red wine intake	0.6	0.9	2.4	0.9	1.5	-1.1	0.1	0.4	0.7	1.1	0.7	1.4
Handedness (chirality/laterality): Left-handed	0.8	0.9	2.6	-0.8	-1.6	0.3	-0.7	-0.0	-0.4	-1.5	0.2	-1.4
Mood swings	1.2	2.1	5.4	1.3	-0.5	2.3	-0.2	1.7	-1.9	-0.3	-2.3	-0.4
Loneliness, isolation	0.6	0.8	2.1	-1.0	0.3	-1.4	-0.4	-0.5	1.1	0.1	1.5	0.3
Long-standing illness, disability or infirmity	0.3	0.4	2.8	-0.3	0.1	-0.5	1.7	-0.2	-0.5	0.3	-0.2	0.1
Ever had bowel cancer screening	0.3	0.4	0.8	0.5	0.7	-0.5	-0.2	-0.8	-0.1	0.9	-0.7	0.9
Diabetes diagnosed by doctor	0.4	0.7	3.3	0.6	0.5	0.0	1.8	0.9	-0.9	0.6	-0.7	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	2.6	-0.4	-1.0	0.4	0.6	0.9	-1.6	-0.8	-0.9	-1.3
Friendships satisfaction	1.0	1.2	3.2	-0.7	0.9	-1.5	0.8	-0.8	1.8	0.9	1.4	0.6
Qualifications: nursing, teaching	1.6	2.4	5.4	-1.8	-0.7	-1.7	-0.1	-1.9	2.2	-0.8	2.3	-0.7
Commuting to job workplace: Walk	0.3	0.3	1.3	0.4	0.8	-0.4	1.1	-0.0	0.2	0.2	-0.1	0.8
Eye problems/disorders: Cataract	1.2	1.4	4.5	1.3	0.9	0.4	2.1	1.0	-0.8	1.1	-0.9	1.1
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.0	-0.7	0.4	0.3	0.4	-1.0	0.4	0.2	0.3	0.3
Medication for cholesterol	0.6	1.0	3.0	-0.1	1.0	-0.6	0.7	-0.1	1.7	0.9	1.5	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.2	5.2	-1.0	1.0	-2.3	0.5	-1.4	0.5	0.7	0.4	0.9
Back pain experienced in last month	0.3	0.4	0.7	-0.8	-0.8	-0.4	0.8	0.7	-0.4	-0.4	-0.4	-0.8
Mineral and other dietary supplements	1.3	1.7	4.3	0.6	-1.0	0.8	2.0	1.6	-2.1	-0.7	-0.8	-1.1
Breast cancer (self-reported)	0.8	1.0	2.2	0.7	0.6	1.1	1.5	0.9	-1.0	0.8	-1.1	0.7
Asthma (self-reported)	0.1	0.1	0.4	-0.2	0.5	-0.3	-0.2	0.1	0.6	0.5	0.0	0.4
Osteoporosis (self-reported)	1.1	1.3	3.8	-2.0	-0.5	-0.0	-0.9	-1.5	0.9	-1.2	1.5	-0.7
Osteoarthritis (self-reported)	0.2	0.3	1.2	0.2	0.5	1.1	0.3	0.1	-0.2	0.8	-0.1	0.6
Medication: Aspirin	0.2	0.3	0.7	-0.3	-0.7	-0.7	0.0	-0.0	-0.8	-0.6	-0.2	-0.6
Medication: Gliclazide	1.5	1.7	4.0	1.7	1.2	0.7	1.9	0.2	-0.4	2.0	-1.2	1.3
Illnesses of father: None of the above (group 1)	0.3	0.4	1.2	0.1	-1.1	0.2	-0.3	0.1	0.4	-0.6	0.8	-0.8
Smoking status: Current	0.5	0.9	2.8	0.1	-1.7	0.0	-1.7	0.7	-0.3	-0.1	0.1	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.1	-1.1	0.1	0.1	0.2	0.0	0.4	-0.5	0.7	-0.2
Whole body water mass	1.3	7.5	16.6	4.1	1.2	1.9	3.3	3.1	-2.4	2.3	-3.5	1.3
Leg predicted mass (right)	1.2	6.4	13.7	3.7	1.3	1.3	3.5	2.3	-1.9	2.5	-3.3	1.5
Arm fat mass (left)	0.5	2.0	4.0	1.5	0.6	0.5	2.0	1.9	-1.6	0.9	-1.8	0.7
Number of self-reported non-cancer illnesses	0.8	1.3	3.7	-1.8	-0.8	-1.9	-0.1	-1.8	0.7	0.0	0.9	-0.4
Average weekly champagne plus white wine intake	2.0	2.7	4.8	-1.4	-2.2	-1.1	-0.8	-1.6	1.1	-2.2	1.7	-2.2
Miserableness	1.0	1.7	4.7	1.6	0.0	1.7	-0.3	1.4	-1.7	0.3	-2.2	0.1
Guilty feelings	0.8	1.2	2.8	1.0	1.1	0.9	1.7	1.1	0.0	1.6	-0.5	1.1
Wears glasses or contact lenses	0.4	0.5	2.3	-0.7	-0.5	-0.4	1.5	-0.5	0.4	-0.2	0.7	-0.5
Ever taken oral contraceptive pill	0.7	0.7	2.3	1.5	0.9	-0.2	0.1	0.7	0.5	1.2	-0.1	1.0
Hearing aid user	1.1	1.2	4.4	-1.0	-0.3	-1.0	2.1	-1.0	1.2	0.3	1.3	-0.3
Mother’s age at death	0.4	0.5	1.5	-1.2	-0.0	-1.2	-0.5	-0.6	0.6	-0.3	1.0	-0.1
Financial situation satisfaction	0.8	0.9	3.3	0.2	0.8	0.8	1.8	0.5	-0.3	1.3	-1.0	0.8
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.8	0.2	0.9	-1.1	-0.6	-1.7	1.0	0.5	0.3	0.8
Commuting to job workplace: Public transport	0.2	0.2	0.9	-1.0	-0.7	-0.1	-0.1	-0.7	0.4	-0.1	0.1	-0.4
Eye problems/disorders: Glaucoma	0.2	0.2	0.6	-0.8	0.1	-0.4	-0.0	-0.7	0.6	0.1	0.6	0.2
Medication: Blood pressure	1.8	3.4	7.5	-2.5	-2.5	-0.5	-1.4	-0.8	-1.1	-2.5	0.2	-2.7
Pain type(s) experienced in last month: Hip pain	1.6	2.1	5.8	1.6	1.2	1.2	1.8	2.4	-0.7	1.4	-0.7	1.1
Supplements: Fish oil (including cod liver oil)	1.2	1.6	4.8	-1.0	0.2	-1.2	-2.2	-1.5	1.7	0.1	1.2	0.3
High cholesterol (Self-reported)	0.3	0.5	1.1	0.7	0.9	-0.7	0.6	-0.1	-0.1	1.0	-0.2	1.1
Medication: Bendroflumethiazide	2.2	3.4	7.6	-1.5	-2.8	-1.3	-1.6	-2.0	-0.1	-2.4	0.5	-2.5
Medication: Paracetamol	1.4	2.2	6.9	-0.8	-1.5	1.0	0.0	-0.3	-2.6	-1.9	-1.7	-1.5
Medication: Lisinopril	0.2	0.2	0.7	-0.4	-0.8	-0.6	0.3	-0.5	-0.1	0.1	0.4	-0.6
Medication: Atorvastatin	0.4	0.5	1.1	0.5	0.8	-1.0	0.9	0.2	0.6	0.6	0.8	0.8
Illnesses of father: High blood pressure	0.3	0.4	1.7	0.4	0.1	0.5	-0.2	-0.1	-1.3	-0.3	-1.3	-0.0
Alcohol drinker status: Never	0.5	0.6	2.8	-1.7	-0.4	0.0	0.2	-0.3	0.2	-1.1	0.8	-0.7
Ever smoked	0.3	0.5	1.4	1.2	0.4	-0.5	-0.1	1.0	0.1	1.0	-0.2	0.8
Basal metabolic rate	1.3	7.4	15.6	3.9	1.1	1.9	3.1	3.2	-2.6	2.1	-3.5	1.2
Leg fat percentage (left)	0.6	2.0	6.0	0.8	-0.7	1.4	0.6	1.9	-2.5	-0.9	-1.9	-0.7
Arm fat-free mass (left)	1.2	6.3	12.8	3.6	0.4	2.5	2.2	3.2	-2.9	1.3	-3.5	0.5
Number of operations (self-reported)	1.3	1.9	3.6	1.1	1.7	0.2	1.3	0.8	-0.8	1.8	-1.7	1.9
Average weekly beer plus cider intake	1.1	1.6	3.3	0.2	-1.8	0.7	-1.5	0.1	-1.5	-1.4	-0.7	-1.8
Irritability	0.1	0.2	0.8	0.8	-0.0	0.9	0.2	0.5	-0.1	0.4	-0.5	0.2
Risk taking	1.9	2.8	7.5	-1.0	-1.0	-2.7	-1.1	-2.3	2.0	-0.8	2.0	-0.8
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.6	0.2	-0.2	0.5	-0.0	-0.2	-0.3	0.2	-1.3	0.1
Fractured/broken bones in last 5 years	1.8	2.3	7.1	-1.4	-0.2	-2.7	1.3	-1.8	1.5	0.3	2.1	-0.1
Age started oral contraceptive pill	0.2	0.3	0.9	-0.5	-0.6	0.6	1.0	0.1	-0.1	-0.6	0.4	-0.6
Diastolic blood pressure, automated reading	0.1	0.3	0.9	-0.7	-0.2	-0.5	-0.3	-0.9	0.5	-0.1	0.8	-0.1
Ever depressed for a whole week	0.2	0.2	1.0	0.5	0.0	0.3	1.0	0.5	0.3	0.6	0.3	0.1
Unable to work because of sickness or disability	0.2	0.2	0.9	0.4	-0.1	-0.7	0.4	-0.9	0.2	0.3	0.3	0.1
Commuting to job workplace: Cycle	0.9	1.1	3.0	1.0	0.3	1.7	1.2	1.1	-1.0	0.3	-1.3	0.3
Myopia	0.2	0.3	2.1	0.0	-0.4	-0.3	0.1	1.4	-0.5	-0.0	-0.2	-0.5
Vascular/heart problems diagnosed by doctor	0.6	1.5	4.5	1.4	2.1	1.0	-0.5	-0.0	0.9	1.1	-0.2	2.0
Cholesterol lowering medication	0.9	1.3	3.4	-0.4	-1.2	0.8	-1.2	0.5	-1.8	-1.3	-1.0	-1.3
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	2.6	-1.6	-1.4	0.0	-0.2	-0.3	-0.2	-1.0	0.5	-1.4
Pain experienced in last month	1.7	2.8	6.8	-0.7	0.2	-2.1	-1.8	-2.1	2.6	0.1	2.4	0.4
Supplements: Calcium	1.9	2.1	6.6	-0.9	0.4	-1.6	-1.9	-2.6	1.9	0.1	1.3	0.5
Basal cell carcinoma (self-reported)	0.7	0.8	2.1	0.9	0.3	0.8	0.6	1.3	-0.9	0.7	-1.5	0.3
Heart attack/myocardial infarction (self-reported)	2.1	2.7	8.0	1.5	-0.2	1.9	1.4	2.8	-2.0	0.6	-1.9	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	1.0	-0.1	0.3	0.1	1.0	-0.5	0.1	0.6	0.0	0.2
Heart disease (siblings)	0.7	0.8	2.6	-0.1	0.1	1.2	1.2	1.6	-0.5	1.3	-0.4	0.3
Alcohol drinker status: Previous	0.5	0.5	1.3	-0.8	0.2	-1.1	0.4	-0.6	1.1	-0.0	1.1	0.1
Pack years of smoking	0.5	0.8	1.9	-0.9	0.6	-0.9	0.7	-0.5	1.4	1.0	1.0	0.5
Impedance of whole body	1.6	8.2	19.0	-3.8	-0.4	-2.3	-4.0	-2.3	3.3	-1.7	4.4	-0.6
Leg fat mass (left)	1.0	4.1	8.5	2.0	-0.1	1.8	2.1	2.9	-2.9	0.0	-2.8	-0.1
Arm predicted mass (left)	1.4	7.3	14.7	3.8	0.6	2.6	2.4	3.6	-3.0	1.5	-3.7	0.6