TWAS hub - QSER1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1210	0.0360	2.8e-07	0.047	0.062	0.056	0.064	0.047	2.1e-06	4.9e-08	1.9e-07	2.9e-08	2.0e-06
2	GTEx	Adrenal Gland	0.2675	0.0969	3.1e-03	-0.005	NA	-0.008	NA	-0.005	5.2e-01	NA	8.9e-01	NA	5.7e-01
3	GTEx	Brain Hypothalamus	0.3090	0.0960	1.2e-03	0.111	NA	-0.003	NA	0.071	1.5e-03	NA	3.8e-01	NA	9.8e-03
4	GTEx	Cells Transformed fibroblasts	0.0780	0.0380	8.6e-03	0.022	NA	0.063	NA	0.039	8.5e-03	NA	1.8e-05	NA	6.4e-04
5	GTEx	Nerve Tibial	0.1557	0.0473	6.8e-06	0.133	NA	0.114	NA	0.124	1.2e-09	NA	2.0e-08	NA	4.4e-09
6	GTEx	Ovary	0.3920	0.1300	5.4e-03	-0.006	NA	0.075	NA	0.062	4.7e-01	NA	6.9e-03	NA	1.3e-02
7	METSIM	Adipose	0.0458	0.0168	2.2e-04	0.030	0.028	0.022	0.028	0.018	2.4e-05	4.6e-05	2.7e-04	4.4e-05	7.9e-04
8	ROSMAP	Brain Pre-frontal Cortex	0.0980	0.0331	6.1e-06	0.047	0.035	0.033	0.036	0.041	9.0e-07	2.1e-05	4.0e-05	1.6e-05	4.7e-06
9	TCGA	Breast Invasive Carcinoma	0.0159	0.0104	5.8e-03	0.007	0.007	0.003	NA	0.005	1.2e-02	1.0e-02	5.7e-02	NA	2.2e-02
10	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0730	0.0400	1.0e-03	0.088	0.051	0.065	NA	0.075	9.4e-06	6.9e-04	1.3e-04	NA	4.6e-05
11	TCGA	Thyroid Carcinoma	0.0460	0.0220	1.7e-05	0.041	0.052	0.052	NA	0.048	7.4e-05	8.5e-06	7.9e-06	NA	1.8e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Prostate Cancer	6.0	8.4	19.9	-2.6	-2.4	-3.4	-2.3	-2.7	-0.8	0.0	-4.3	-2.4	-4.5	-3.3
Illnesses of siblings: Diabetes	4.6	5.7	11.7	-3.4	-0.6	-3.2	0.5	-2.7	1.2	1.2	-2.8	-2.5	-2.9	-2.7
Wears glasses or contact lenses	3.5	4.0	7.7	1.8	2.7	2.4	2.0	2.4	-0.1	-0.9	2.0	1.6	1.7	2.8
Bilateral oophorectomy (both ovaries removed)	3.4	4.0	12.7	1.4	3.6	1.2	3.0	2.4	-0.7	0.7	1.5	2.6	1.2	1.3
Blood Platelet Count	3.0	34.3	52.6	-6.8	-7.2	-4.7	-7.0	-7.1	-0.9	-4.3	-6.2	-4.3	-5.9	-6.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.7	3.2	7.8	2.8	1.9	1.0	1.6	2.2	1.3	1.2	1.7	1.6	1.3	2.1
Chronic bronchitis/emphysema (father)	2.6	3.1	6.2	-1.2	-0.7	-2.4	-2.4	-2.5	-0.2	-1.2	-1.5	-1.5	-1.8	-2.2
Wheeze or whistling in the chest in last year	2.6	4.6	10.5	-1.4	0.9	-3.2	-0.8	-2.8	0.1	-0.6	-2.4	-2.7	-2.7	-2.7
Type 2 Diabetes (T2D) (2012)	2.5	2.9	7.8	-0.1	0.9	-1.9	0.9	-1.2	-2.2	1.4	-1.9	-2.8	-2.1	-1.4
Emphysema/chronic bronchitis	2.5	2.8	6.5	-1.5	0.3	-2.3	0.3	-2.1	-0.4	0.7	-2.4	-1.6	-2.5	-1.9
Pain type(s) experienced in last month: Hip pain	2.5	3.2	6.0	-1.9	-2.1	-2.4	-2.1	-2.1	1.1	-0.3	-2.0	-1.1	-1.8	-1.6
Waist Hip Ratio (WHR)	2.4	11.0	22.4	-2.5	-3.8	-3.4	-4.7	-4.1	0.5	-0.9	-3.0	-4.0	-3.1	-3.6
Number of children fathered	2.4	2.7	6.3	-2.5	-1.2	-1.9	-1.0	-2.1	0.4	0.3	-1.9	-1.3	-1.7	-2.0
Health satisfaction	2.3	3.0	14.6	-0.8	0.8	-1.8	2.0	-0.4	3.8	1.8	-1.3	-0.2	-1.4	-1.6
Diabetes (father)	2.2	2.7	4.5	-2.0	0.4	-1.4	-0.0	-1.8	-1.9	2.0	-1.6	-1.7	-1.5	-2.1
Happiness	2.2	2.7	6.2	-1.4	-1.6	-2.5	0.7	-1.7	1.8	0.3	-1.6	-1.5	-1.6	-2.1
Noisy workplace	2.2	2.7	5.3	2.3	1.8	1.2	1.8	1.3	0.6	1.9	1.6	1.1	1.5	2.0
Bipolar Disorder (2011)	2.1	2.0	3.9	-1.4	-1.7	-1.3	2.0	-0.7	-0.5	-0.1	-1.5	-1.7	-1.6	-1.8
Medication: Co-codamol	2.1	2.5	6.0	-1.6	-1.1	-2.0	-1.1	-1.3	-0.5	-0.6	-2.4	-1.3	-2.4	-1.6
Birth weight	2.1	4.7	8.2	1.4	-1.9	2.7	-2.8	0.7	-2.9	-0.8	2.6	2.4	2.6	1.5
Exposure to tobacco smoke outside home	2.1	2.8	4.5	1.5	1.8	2.0	1.1	2.1	-1.7	0.8	1.9	1.4	1.8	1.7
Respiratory disease	2.0	4.5	9.9	-1.4	-0.0	-3.0	-1.3	-2.7	-0.7	-0.5	-2.4	-3.2	-2.6	-2.4
Illnesses of siblings	2.0	2.8	7.6	0.2	-0.6	2.7	-0.0	2.0	-1.6	-1.0	1.7	2.8	1.7	1.5
Deep venous thrombosis (DVT) (self-reported)	2.0	2.5	8.9	3.0	1.5	1.3	2.1	1.2	-0.1	1.1	1.9	-0.2	1.8	0.9
Fasting Glucose	1.9	2.3	9.7	-1.7	0.2	-1.6	-3.1	-1.8	0.5	0.8	-1.5	-0.5	-1.5	-1.1
Blood clot in the leg (DVT)	1.9	2.4	9.1	3.0	1.3	1.3	2.0	1.3	0.1	0.9	1.9	-0.1	1.7	0.9
Mouth/teeth dental problems: Mouth ulcers	1.9	3.0	8.7	0.9	2.0	1.4	1.2	1.7	0.3	2.9	1.7	1.9	1.6	1.9
Age started oral contraceptive pill	1.9	2.4	5.3	2.1	0.2	2.1	-0.2	2.0	-0.1	-0.9	1.5	1.5	1.5	2.3
Father’s age at death	1.8	2.5	5.9	-1.1	-2.4	-0.5	-2.0	-1.4	-2.1	-2.1	-1.1	-1.5	-0.8	-0.8
Medication: Ventolin 100micrograms inhaler	1.8	2.3	6.2	-1.8	-0.7	-1.4	-2.5	-2.1	-0.9	-2.0	-0.7	-1.1	-0.6	-1.5
Medication for pain relief, constipation, heartburn	1.8	3.0	6.3	-2.1	-2.3	-1.2	-2.5	-2.2	-0.2	-1.4	-1.7	-1.3	-1.4	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.2	5.5	0.9	2.3	1.0	1.8	1.8	0.3	0.3	1.4	2.0	1.3	1.4
Medication: Lansoprazole	1.7	1.9	2.9	1.5	1.6	1.6	0.6	1.7	-0.7	1.0	1.5	1.3	1.4	1.7
Worry too long after embarrassment	1.7	2.9	9.9	1.5	1.7	1.0	3.2	1.6	0.7	1.0	1.8	2.2	1.5	1.1
Medication: Ibuprofen	1.7	2.1	5.1	1.3	1.2	1.4	2.2	2.1	0.1	1.1	1.3	1.2	1.1	1.6
Smoking status: Previous	1.7	2.5	5.7	-2.1	1.3	-2.1	0.6	-1.2	1.1	1.0	-2.2	-0.9	-2.4	-1.5
Financial situation satisfaction	1.7	2.1	17.8	0.8	0.4	-0.2	0.4	0.2	4.2	0.2	0.7	1.4	0.9	1.1
Triglycerides	1.6	2.6	6.5	2.5	1.3	2.4	1.0	2.0	-0.7	-0.7	1.7	1.1	1.6	1.3
Illnesses of mother	1.6	2.0	6.7	-1.3	-2.6	-0.9	-1.7	-0.8	-0.5	-1.7	-1.2	-1.4	-1.2	-1.2
Medication: Blood pressure	1.6	2.8	9.9	1.0	2.9	0.2	2.8	1.2	0.8	3.1	0.1	0.9	0.2	1.2
Breast Cancer	1.5	3.5	7.1	2.3	1.3	1.4	-0.8	1.8	1.6	-1.1	2.2	2.7	2.2	2.2
Asthma	1.5	2.9	6.9	-0.8	1.1	-2.4	-1.4	-2.3	-1.2	0.1	-1.7	-2.6	-1.9	-1.5
Medication: Seretide 50 evohaler	1.5	1.7	3.3	-0.8	-1.2	-1.6	-1.4	-1.4	-0.8	-1.7	-1.2	-1.0	-1.1	-1.8
Asthma (self-reported)	1.5	3.0	7.0	-0.7	0.9	-2.6	-1.5	-2.4	-0.9	-0.2	-1.7	-2.6	-1.9	-1.6
Irritability	1.5	2.6	4.4	-1.9	-0.0	-2.0	-0.4	-1.8	-1.3	2.1	-1.6	-1.5	-1.6	-1.9
Hearing difficulty/problems: Yes	1.4	2.1	3.8	1.7	1.0	2.0	1.7	1.7	-0.6	0.3	1.5	1.1	1.5	1.8
Number of incorrect matches in round	1.4	2.3	10.1	1.6	0.4	1.8	0.3	1.4	-3.2	-0.2	1.3	-0.8	1.2	1.6
Heart attack	1.4	1.8	6.5	1.7	2.6	1.2	1.9	1.2	0.8	-0.1	0.9	-0.8	0.8	1.2
Suffer from ‘nerves’	1.4	2.3	5.4	1.0	2.3	0.6	2.3	1.5	0.7	-0.0	1.6	2.0	1.4	1.4
Knee pain experienced in last month	1.4	2.1	5.9	0.9	1.4	0.8	1.3	1.1	0.0	2.4	1.5	2.3	1.4	1.3
Medication: Paracetamol	1.4	2.2	5.4	2.3	1.9	1.2	1.3	2.0	-0.3	-0.3	1.4	1.3	1.4	1.5
Alcohol drinker status: Previous	1.4	1.6	5.5	2.4	0.6	0.7	1.1	0.5	1.8	1.0	1.6	0.4	1.6	0.8
Neuroticism (2016)	1.3	1.8	6.0	1.4	2.5	-0.1	2.0	1.3	1.1	0.8	0.5	1.9	0.4	0.7
Type 2 Diabetes (T2D) (2018)	1.3	2.4	5.5	-1.0	0.1	-1.6	0.6	-1.8	1.0	1.5	-1.9	-1.9	-1.8	-2.3
Neuroticism score	1.3	2.8	12.2	1.3	2.5	0.5	3.5	1.0	1.3	1.6	1.3	1.1	1.1	1.1
High blood pressure (siblings)	1.3	1.9	4.6	-0.3	1.4	-2.1	0.8	-1.0	1.0	1.9	-1.3	-1.9	-1.3	-0.8
Mean time to correctly identify matches	1.3	2.5	4.7	2.2	1.7	2.0	0.9	1.4	-1.2	0.6	1.9	-0.5	1.6	2.1
Reaction Time	1.2	2.3	5.4	1.7	0.7	2.3	1.3	1.7	-1.3	1.1	1.8	-0.7	1.6	1.7
Neuroticism	1.2	2.9	9.8	1.4	2.1	0.8	3.1	1.5	1.4	1.8	1.3	1.7	1.2	1.3
Fed-up feelings	1.2	2.3	8.3	0.6	2.3	-0.1	2.9	0.9	1.8	2.1	0.6	1.4	0.5	0.5
Medication: Atenolol	1.2	1.5	3.7	1.0	1.8	1.0	1.2	1.9	0.6	1.4	0.7	0.9	0.7	1.4
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	3.1	-1.3	0.4	-1.5	-0.3	-1.8	-1.3	1.7	-1.5	-1.6	-1.3	-1.6
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	5.6	-1.1	2.2	-1.4	0.7	-0.8	-0.3	2.4	-1.4	-1.3	-1.6	-0.7
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	4.7	1.1	1.0	0.9	2.2	1.8	-0.1	0.6	1.1	1.3	0.8	1.2
Medication: Paracetamol	1.2	2.0	5.1	2.1	2.3	1.0	1.3	1.9	-0.2	0.4	1.1	1.3	1.1	1.4
Eye problems/disorders: Glaucoma	1.2	1.4	4.5	0.8	2.1	0.8	0.2	1.3	0.4	-2.0	1.3	0.6	1.1	0.9
Ever smoked	1.2	2.1	4.2	-1.1	1.9	-1.9	2.0	-0.9	1.6	1.4	-0.9	-0.4	-1.2	-1.6
Alzheimer’s Disease (in mother)	1.1	1.2	4.4	-2.1	0.3	-0.6	-1.6	-1.3	-0.9	1.2	-0.3	0.6	-0.3	-1.2
Coronary Artery Disease (CAD)	1.1	1.3	4.9	0.7	-0.1	1.0	0.5	1.0	2.2	1.2	1.2	1.0	1.4	1.2
Chronotype (morning person)	1.1	2.6	6.5	1.8	2.0	0.3	2.2	0.7	-1.9	2.5	1.2	-0.6	1.2	1.6
Diabetes (mother)	1.1	1.3	5.9	1.2	2.4	-0.1	0.3	-0.2	2.2	1.5	0.3	0.0	0.3	0.6
Severe depression (siblings)	1.1	1.2	3.4	-0.6	-1.7	-1.3	0.2	-0.4	0.1	-0.6	-1.8	-0.0	-1.8	-1.0
Stomach or abdominal pain in last month	1.1	1.4	4.4	-0.6	-1.3	-2.1	-0.2	-1.0	1.1	-0.3	-1.5	-0.8	-1.4	-1.3
Hair/balding pattern: Pattern 2	1.1	1.4	7.3	-0.0	-1.3	0.4	-1.6	0.4	1.8	-2.7	0.2	-0.2	0.4	0.6
Exposure to tobacco smoke at home	1.1	1.2	3.3	0.6	1.7	1.5	-0.2	1.0	-1.1	1.8	0.6	1.1	0.6	1.0
Pulse wave reflection index	1.1	1.3	7.2	-1.0	1.0	0.4	-1.0	-1.0	-2.7	-0.1	-0.4	-0.6	-0.4	-1.7
Glaucoma (self-reported)	1.1	1.3	3.6	0.9	1.9	1.2	0.2	1.3	-0.1	-1.2	1.4	1.1	1.2	1.1
Handedness (chirality/laterality): Left-handed	1.1	1.3	3.0	1.1	1.3	1.7	-0.1	1.2	-1.3	-1.4	1.0	1.1	0.8	0.7
Cholesterol lowering medication	1.1	1.6	8.1	-0.6	-0.7	-0.8	-2.9	-1.7	-0.6	-0.9	-0.8	-1.5	-0.5	-1.0
Heart attack/myocardial infarction (self-reported)	1.1	1.5	6.5	1.4	2.5	1.1	1.5	0.9	0.4	0.1	0.8	-0.9	0.7	1.1
Depressed Affect (Nagel 2018)	1.0	2.1	9.2	0.5	1.3	-1.3	3.0	-0.3	1.7	2.5	-0.3	-0.1	-0.6	0.0
Depression (Nagel 2018)	1.0	1.5	4.3	-0.4	0.8	-2.1	0.2	-1.4	1.6	1.9	-0.8	-0.9	-0.8	-1.2
Body Mass Index (BMI) (2010)	1.0	1.3	6.7	-0.6	1.5	-0.7	1.5	-0.5	-2.6	0.5	-0.5	-1.0	-0.7	-0.7
Maternal smoking around birth	1.0	1.5	5.7	0.9	0.5	0.7	2.4	1.9	-0.7	1.3	-0.4	1.2	-0.6	-1.0
Qualifications: CSEs or equivalent	1.0	1.3	3.3	1.1	0.7	1.4	1.3	1.8	1.3	-0.2	0.2	1.6	0.4	1.0
Past tobacco smoking	1.0	1.8	4.0	1.5	-1.8	1.6	-1.4	0.6	-2.0	-0.9	1.2	-0.0	1.4	1.2
Had other major operations	1.0	1.2	8.9	0.6	0.3	-0.5	1.1	0.8	3.0	0.2	-0.1	1.2	0.0	0.4
Birth weight of first child	1.0	1.9	16.2	-1.0	-4.0	-0.1	-1.2	-0.4	-0.9	-0.0	0.0	0.8	0.1	0.1
Pulse wave peak to peak time	1.0	1.2	4.5	0.3	1.1	1.2	2.1	1.7	-0.2	0.5	0.5	0.9	0.3	1.3
Mood swings	1.0	1.9	12.1	0.9	1.5	-0.2	3.5	1.1	-0.0	2.0	0.0	0.7	-0.2	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.1	5.8	-1.5	-0.7	-1.4	1.3	-0.1	-1.3	0.9	-2.0	0.4	-2.4	-2.2
Basal cell carcinoma (self-reported)	1.0	1.2	4.0	-0.1	0.5	1.2	1.3	1.2	0.8	0.5	1.2	2.0	1.0	0.8
HDL Cholesterol	0.9	1.5	4.8	-1.0	-1.6	-0.7	-1.7	-0.6	1.9	-2.2	-0.4	0.3	-0.2	-0.5
LDL Cholesterol	0.9	1.4	2.3	1.5	1.4	1.2	0.5	1.2	-1.0	0.6	1.4	0.9	1.4	1.4
Medication for hormone replacement therapy	0.9	1.0	3.8	0.1	-0.3	-1.6	1.9	-0.5	-0.2	0.5	-0.9	-0.8	-1.0	-1.1
Relative age voice broke	0.9	1.3	5.5	-0.9	-1.5	0.7	-0.8	-0.2	-2.4	1.9	0.5	-0.4	0.8	0.7
Supplements: Glucosamine	0.9	1.1	4.0	-0.4	-1.6	0.1	-1.8	0.2	1.3	-0.6	-0.1	2.0	0.1	0.3
Qualifications: A levels/AS levels or equivalent	0.9	1.9	4.6	-1.2	-2.0	-0.3	-2.1	-1.4	-0.9	-1.8	-0.7	-1.5	-0.7	-1.0
Tense / ‘highly strung’	0.9	1.4	3.8	0.6	1.6	0.4	1.4	0.5	-0.8	1.6	1.9	0.3	1.8	0.6
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	5.9	-0.9	-1.8	0.3	-2.4	-0.7	-0.3	-2.3	0.2	-0.1	0.2	-0.3
Chronic bronchitis/emphysema (mother)	0.9	1.1	2.7	-0.2	-0.2	-1.6	0.3	-1.6	-0.7	0.2	-0.9	-1.6	-1.0	-1.3
Alcohol intake frequency.	0.9	2.1	7.0	2.4	1.4	-0.8	2.2	-0.1	2.6	-1.0	0.6	-0.1	0.6	0.6
Number of full sisters	0.9	1.0	2.3	0.0	0.2	-1.2	0.8	-0.4	1.2	1.5	-1.5	0.0	-1.5	-1.1
Had major operations	0.9	1.1	3.3	-1.0	-0.6	-1.4	0.5	-1.0	-0.5	0.1	-1.2	-0.7	-1.4	-1.8
Commuting to job workplace: Car/motor vehicle	0.9	1.0	2.7	-0.5	-1.3	-1.0	-0.7	-0.4	-0.3	-0.9	-1.5	-0.7	-1.6	-1.0
Medication: Aspirin	0.9	1.2	5.0	0.7	1.9	0.5	1.8	0.1	0.2	2.2	0.7	-0.3	0.5	0.1
Commuting to job workplace: Public transport	0.9	1.1	2.7	0.9	1.0	1.2	0.3	0.1	-1.4	-0.6	1.7	-0.2	1.5	1.0
Neuroticism (Nagel 2018)	0.8	1.9	8.1	1.0	1.6	-0.8	2.8	0.3	1.2	1.8	1.0	1.3	0.8	0.7
Worry (Nagel 2018)	0.8	1.6	4.9	0.7	2.2	-0.2	2.1	0.7	0.5	1.1	1.5	1.2	1.3	0.9
HbA1C	0.8	0.9	2.0	-1.0	-0.6	-1.4	0.0	-1.3	0.8	-0.7	-0.3	-1.1	-0.4	-1.3
Blood Eosinophil Count	0.8	6.5	16.1	-2.1	-0.6	-3.5	-0.0	-3.4	-0.9	0.1	-2.8	-4.0	-2.8	-3.3
Sensitivity / hurt feelings	0.8	1.4	10.2	0.4	0.2	0.6	3.2	1.3	-0.4	0.2	0.6	1.4	0.3	0.7
Relative age of first facial hair	0.8	1.6	6.8	-1.5	-1.9	1.1	-1.3	0.1	-0.5	2.6	0.6	-0.2	0.8	1.0
Ever used hormone-replacement therapy (HRT)	0.8	1.0	5.2	1.1	0.6	-0.6	0.5	0.4	2.3	-0.4	0.7	1.2	0.6	0.9
Medication: Metformin	0.8	1.1	3.0	-0.5	-0.5	-0.9	-1.0	-1.7	0.8	0.3	-1.1	-1.6	-0.9	-1.3
Average weekly fortified wine intake	0.8	1.0	6.2	-1.1	-0.5	0.6	-2.5	-0.2	-0.6	-0.1	-0.1	1.4	-0.1	-0.6
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	2.5	-0.2	-0.3	-1.6	-0.0	-1.6	0.8	0.3	-0.9	-0.8	-1.0	-0.9
Diabetes (self-reported)	0.8	1.3	3.1	-0.6	0.7	-1.2	0.4	-1.3	-0.2	1.5	-1.2	-1.3	-1.1	-1.8
Time employed in main current job	0.8	1.0	2.6	-0.6	0.9	0.6	0.8	1.4	1.6	-0.6	0.5	1.3	0.2	1.2
Headache pain in last month	0.8	1.3	8.8	1.3	0.7	-0.5	3.0	0.6	0.4	1.3	0.7	0.1	0.5	0.5
Overall health rating	0.8	1.7	6.4	0.5	2.5	-1.0	2.4	0.6	1.8	1.5	0.3	-0.2	-0.1	0.0
Age at last live birth	0.8	1.2	3.2	0.2	-1.0	1.8	0.4	1.1	-0.6	-1.0	1.1	1.5	1.0	1.4
Family relationship satisfaction	0.8	1.0	4.5	1.4	-0.3	-0.3	1.8	0.4	2.1	-0.2	0.7	-0.2	0.5	0.1
Hypertension (Self-reported)	0.8	2.3	6.4	0.5	2.4	0.5	2.5	1.2	-0.3	2.5	0.7	1.0	0.9	1.6
Loneliness, isolation	0.8	1.0	4.1	0.5	1.8	-0.2	2.0	-0.4	0.9	1.2	0.3	-0.9	0.2	-0.7
Diabetes diagnosed by doctor	0.8	1.3	3.3	-0.5	0.1	-1.3	0.5	-1.4	0.8	1.8	-1.1	-1.3	-1.0	-1.7
Back pain experienced in last month	0.8	1.2	3.7	0.6	1.8	0.0	1.3	0.7	1.9	1.4	0.8	0.3	0.9	0.4
Osteoporosis (self-reported)	0.8	1.0	2.6	-1.6	0.2	-1.4	1.0	-0.7	-0.9	-0.5	-0.7	-1.2	-1.0	-1.3
Average weekly champagne plus white wine intake	0.8	1.1	3.3	-1.8	-1.8	0.1	-1.4	0.2	-0.2	-0.6	-1.2	-0.5	-1.1	-0.2
Ever taken oral contraceptive pill	0.8	0.8	1.7	-0.5	-0.8	-1.0	-0.8	-0.8	0.7	-0.1	-1.2	-1.0	-1.2	-1.3
Mother’s age at death	0.8	1.0	5.0	1.1	-0.2	0.7	0.6	0.1	-2.2	0.4	1.2	-0.2	1.2	0.8
Average weekly beer plus cider intake	0.8	1.1	5.1	-0.8	-1.6	-1.2	-0.7	-0.6	2.3	0.2	-0.7	-0.3	-0.8	-0.7
Risk taking	0.8	1.2	3.2	-0.9	0.9	-0.7	-0.6	-1.4	-1.4	1.1	-0.6	-1.8	-0.8	-1.1
Unable to work because of sickness or disability	0.8	1.0	4.2	0.2	-0.4	-1.3	1.0	-0.4	2.0	0.7	-0.8	-1.3	-0.8	-0.5
Supplements: Calcium	0.8	0.8	1.6	0.9	0.5	1.1	-0.6	1.2	-0.0	-0.5	1.0	1.1	1.0	1.2
Schizophrenia (2018)	0.7	1.4	4.2	-2.1	-0.3	-0.8	0.5	-1.0	-0.6	0.0	-1.6	-0.8	-1.7	-1.6
Alzheimer’s Disease (including proxy)	0.7	1.0	3.6	-1.6	-0.3	0.0	-1.9	-0.6	-1.2	1.1	-0.4	0.3	-0.4	-1.0
Verbal and Numeric Reasoning (VNR)	0.7	1.8	6.4	-1.2	-2.5	-0.8	-0.7	-0.9	-0.9	-1.6	-1.2	-1.4	-1.1	-1.4
Lupus	0.7	1.1	3.4	1.0	-0.1	-0.1	-0.4	-0.2	0.9	1.3	1.7	0.4	1.9	1.4
Schizophrenia (2014)	0.7	1.4	4.0	-2.0	-0.7	-0.9	-0.2	-1.0	-0.5	-1.0	-1.6	-1.2	-1.6	-1.4
Cardiovascular Disease	0.7	2.2	9.9	0.9	2.1	0.4	2.2	1.0	0.5	3.1	0.5	0.7	0.7	1.1
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.3	0.8	1.5	0.1	1.2	-0.1	0.8	0.1	1.4	0.9	1.3	0.6
Supplements: Zinc	0.7	0.8	2.3	1.0	0.3	1.1	-0.9	1.3	-0.5	0.4	0.3	1.1	0.4	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.7	-0.7	0.7	-1.1	0.5	-1.3	-0.0	0.5	-1.0	-1.0	-1.0	-1.7
Taking other prescription medications	0.7	1.2	3.1	-0.4	1.8	-1.8	0.3	-1.3	-0.4	0.6	-0.6	-1.7	-0.8	-0.5
High blood pressure	0.7	1.8	7.2	0.0	2.2	-0.2	2.4	0.5	-1.0	2.7	0.1	0.2	0.3	0.9
Forced vital capacity (FVC)	0.7	2.8	11.6	1.1	0.3	1.3	3.0	2.4	0.7	0.2	0.7	3.4	0.6	0.1
Allergy	0.7	1.7	4.8	0.6	-0.6	2.0	0.7	0.8	0.5	-0.3	1.8	1.5	2.2	1.3
Fluid intelligence score	0.7	1.4	4.1	-1.4	-2.0	-0.5	-0.3	-1.6	-1.1	-1.7	-0.1	-1.0	-0.0	-1.2
Hair/balding pattern: Pattern 3	0.7	1.1	7.9	-0.7	2.8	-0.5	-0.1	-0.8	-0.3	1.4	-0.0	0.1	-0.4	-0.4
Pulse rate	0.7	1.2	5.7	0.7	-1.9	-0.8	-0.2	-0.1	2.4	1.1	-0.0	0.1	0.2	1.1
Depression (self-reported)	0.7	0.9	2.4	0.9	1.5	0.6	1.6	0.4	1.1	1.1	0.8	-0.2	0.6	0.5
Lung cancer (father)	0.7	0.8	2.7	1.1	0.9	-0.6	1.6	0.8	1.2	1.0	-0.3	-0.2	-0.3	0.1
Pulse wave Arterial Stiffness index	0.7	0.8	3.4	-0.1	-1.1	-0.9	-1.8	-1.3	0.2	-0.6	-0.3	-0.6	-0.1	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.8	0.5	0.9	-0.7	1.7	-0.1	0.7	-0.3	-0.8	-1.6	-1.0	-0.8
Neck or shoulder pain in last month	0.7	1.0	3.0	-0.6	-0.3	-1.7	1.0	-1.0	1.1	0.9	-0.8	-1.3	-0.7	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	3.8	-2.0	-0.0	-1.5	-0.1	-1.4	-0.1	1.2	-1.4	-1.3	-1.4	-1.4
Miserableness	0.7	1.2	2.9	-0.7	1.2	-1.6	0.9	-1.1	0.8	1.7	-1.1	-0.4	-1.1	-0.6
Medication: Lisinopril	0.7	0.9	4.4	1.0	0.8	1.1	0.7	1.1	-2.1	-0.1	0.5	-0.4	0.5	0.8
Pain experienced in last month	0.7	1.2	6.9	-0.3	-0.2	0.5	-1.3	-0.3	-1.5	-2.6	-0.4	-1.1	-0.2	-0.6
Ulcerative Colitis	0.6	0.9	1.8	-0.7	-0.3	-0.6	-0.8	-1.2	-1.3	1.0	-0.7	-1.3	-0.7	-1.2
Systolic Blood Pressure	0.6	2.8	5.3	-1.8	0.9	-2.1	0.1	-2.1	-1.0	2.3	-2.0	-1.7	-1.6	-1.1
Smoking Status	0.6	1.3	4.0	-1.4	1.1	-1.3	2.0	-0.8	0.2	0.5	-0.8	-0.9	-1.1	-1.5
Pack years adult smoking proportion	0.6	0.9	2.5	0.9	0.5	-0.2	1.6	-0.2	-0.1	1.2	-0.1	-1.6	-0.2	-1.3
Serious illness, injury or assault to yourself	0.6	0.8	2.7	1.6	1.2	0.1	1.4	0.6	0.4	0.1	0.8	0.8	0.7	0.6
Medication: Levothyroxine sodium	0.6	1.0	2.7	1.0	0.4	1.0	1.6	1.4	-0.9	0.8	1.0	0.0	1.1	0.6
High blood pressure (mother)	0.6	0.9	3.9	0.0	1.9	-0.3	0.9	-0.3	-0.8	2.0	0.4	0.1	0.6	0.1
Alcohol usually taken with meals	0.6	1.0	4.4	-0.2	-1.6	0.7	-0.1	0.9	-0.3	-2.1	0.7	0.5	0.8	1.1
Alcohol intake versus 10 years previously	0.6	0.9	3.0	-0.0	1.3	-1.7	1.5	-0.4	1.2	0.7	-0.6	0.3	-0.7	-0.4
Falls in the last year	0.6	0.8	3.9	0.2	0.6	0.2	2.0	0.4	0.8	1.0	1.0	0.8	1.1	0.4
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	9.1	-0.4	-0.5	0.9	2.3	1.8	-0.4	1.1	-0.4	3.0	-0.4	-0.8
Medication: Cholesterol lowering	0.6	0.9	6.1	0.1	1.4	0.2	2.5	0.8	0.4	0.9	0.1	0.1	-0.0	-0.2
Prospective memory result	0.6	0.8	2.3	-0.3	-0.2	-1.5	0.9	-1.3	-0.5	0.5	-0.5	-1.2	-0.7	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	7.0	-0.7	-0.8	0.5	2.4	1.7	0.5	0.9	-1.1	2.6	-1.2	-0.9
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.0	-0.7	-1.3	1.1	-0.0	1.4	-0.8	1.0	-0.2	1.1	-0.1	0.3
Qualifications: College or University degree	0.6	1.8	6.0	-1.0	-2.4	-0.4	-2.3	-0.5	-0.7	-1.7	-1.2	-0.8	-1.1	-0.8
Medication: Aspirin	0.6	0.8	3.5	0.8	1.4	0.5	1.4	0.0	0.2	1.9	0.4	-0.5	0.3	0.0
Long-standing illness, disability or infirmity	0.6	0.8	3.0	-0.8	0.6	-1.7	0.3	-1.5	0.5	0.5	-0.6	-0.9	-0.6	-0.9
Friendships satisfaction	0.6	0.7	6.1	-0.6	0.3	-0.5	0.7	-0.4	2.5	0.7	-0.1	0.1	-0.5	0.3
Guilty feelings	0.6	0.9	3.8	0.3	1.0	0.2	1.4	-0.1	2.0	-0.3	1.1	0.5	1.1	0.8
Medication: Blood pressure	0.6	1.1	2.5	0.4	1.1	1.0	1.2	0.9	-1.6	0.3	1.2	0.9	1.4	0.9
Illnesses of father: High blood pressure	0.6	0.7	2.1	0.5	0.8	0.2	1.2	0.5	-0.6	1.5	0.7	0.2	0.9	1.2
Number of operations (self-reported)	0.6	0.9	5.1	0.6	0.1	-0.8	1.7	0.2	2.3	0.7	0.1	0.9	-0.1	-0.1
Vascular/heart problems diagnosed by doctor	0.6	1.5	5.8	-0.5	-2.4	0.2	-2.3	-0.6	0.3	-1.9	-0.0	0.1	-0.2	-1.0
Bipolar Disorder or Schizophrenia	0.5	1.2	2.7	-1.6	-0.5	-0.7	1.5	-0.6	0.0	0.2	-1.3	-1.2	-1.4	-1.4
Schizophrenia vs Biploar Disorder	0.5	0.7	3.5	-0.8	-0.4	-0.3	-1.2	-0.6	-1.9	-0.4	-0.7	-0.0	-0.5	-0.6
Ulcerative Colitis (UC)	0.5	0.9	3.0	-0.3	-0.7	-1.0	0.6	-1.0	-1.2	0.1	-0.6	-1.7	-0.8	-1.1
Ovarian Cancer	0.5	0.7	2.9	-0.1	1.2	0.6	-0.2	0.4	0.3	-1.7	-1.0	-0.4	-1.1	-0.1
Age at First Birth	0.5	0.8	7.1	-0.7	-0.1	-0.5	-2.7	-0.5	-0.5	-0.4	-0.2	0.3	-0.3	0.3
Blood Red Count	0.5	4.4	13.3	-3.6	-1.6	-1.9	-1.7	-2.1	-0.9	0.1	-2.5	-0.4	-2.7	-2.6
Allergy or Eczema	0.5	1.2	3.3	-0.8	-0.9	-1.8	-1.5	-0.4	0.3	-1.4	-1.0	-0.8	-1.3	-0.9
Lung FEV1/FVC ratio	0.5	2.7	8.3	-2.9	-1.3	-0.2	-0.2	0.0	-2.1	1.3	-2.3	-0.1	-2.3	-1.8
Frequency of depressed mood in last 2 weeks	0.5	0.7	3.8	0.4	1.3	-0.7	0.6	-0.1	1.1	1.9	-0.1	0.1	0.1	-0.1
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.9	0.1	0.7	0.4	-1.4	-0.3	0.5	0.7	1.1	-0.4	1.2	0.4
Hearing difficulty/problems with background noise	0.5	0.9	2.6	0.9	0.0	1.0	1.6	0.6	-0.1	-1.5	1.0	-0.1	1.1	0.4
Worrier / anxious feelings	0.5	0.9	3.9	0.2	1.6	-1.0	2.0	-0.1	0.8	-0.2	0.2	1.2	0.1	0.1
Breastfed as a baby	0.5	0.7	1.6	-0.0	-0.4	0.7	-1.3	0.3	0.9	0.7	0.5	1.2	0.5	1.3
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	3.5	0.2	-1.9	1.3	0.6	0.8	-0.1	-1.2	-0.1	-0.6	-0.4	-0.2
Number of full brothers	0.5	0.6	2.9	-0.4	0.2	-0.3	1.7	-0.5	0.2	1.4	0.6	-0.1	0.7	-0.5
Shortness of breath walking on level ground	0.5	0.5	1.7	-0.9	0.3	-0.8	0.4	-0.5	1.1	1.3	-0.4	0.5	-0.3	-0.8
Migraine (self-reported)	0.5	0.6	1.7	0.7	0.3	0.5	-0.8	0.9	0.8	1.0	0.6	1.3	0.6	0.6
Pulse rate, automated reading	0.5	1.6	5.1	0.3	-2.3	-1.8	-0.7	-1.7	0.5	0.6	-1.0	-2.1	-0.5	-0.0
Chest pain or discomfort	0.5	0.8	2.0	-0.5	0.7	-1.2	0.6	-1.4	1.2	1.3	-0.2	-0.2	-0.1	-0.9
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.6	-0.8	-1.1	-0.0	-1.3	-0.4	-1.6	0.3	0.2	-0.2	0.2	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	3.1	0.4	-0.2	0.5	-0.5	0.2	-1.8	-0.3	1.1	0.5	1.0	0.6
Average weekly red wine intake	0.5	0.8	2.2	-1.4	-0.7	-0.1	-0.9	-0.4	-1.5	-1.2	-0.1	1.1	-0.0	-0.0
Commuting to job workplace: Walk	0.5	0.6	1.3	-0.5	-0.9	-1.0	0.3	-0.9	0.5	0.3	-0.7	-1.0	-0.7	-1.1
Mineral and other dietary supplements	0.5	0.6	3.1	-0.5	0.4	0.1	1.8	-0.2	-1.2	1.1	0.0	-0.8	-0.0	-0.1
High cholesterol (Self-reported)	0.5	0.9	2.7	0.9	0.3	-0.6	-0.3	-1.0	-1.6	-1.4	0.5	-1.4	0.5	-0.4
Fractured/broken bones in last 5 years	0.5	0.6	2.0	0.3	-1.1	0.7	0.7	0.1	0.4	0.6	1.4	-0.1	1.4	0.1
Diastolic blood pressure, automated reading	0.5	1.6	6.1	-0.8	0.1	-2.5	-1.0	-1.3	0.7	0.8	-1.8	-0.7	-1.6	-0.7
Ever depressed for a whole week	0.5	0.6	1.6	0.9	0.6	0.4	0.8	1.0	0.2	-0.0	1.0	1.3	0.9	0.5
Myopia	0.5	0.8	3.0	-1.0	-1.0	1.2	-0.6	0.2	1.0	-1.7	-0.1	0.9	-0.1	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.6	-0.1	0.2	-1.3	0.8	-0.4	0.1	1.3	-0.6	-0.7	-1.0	-0.5
Rheumatoid Arthritis	0.4	0.5	3.4	-0.2	0.2	-0.3	-1.8	-0.3	0.2	-1.0	-0.1	-1.0	-0.1	-0.3
Heel T-Score	0.4	3.0	14.2	-2.5	-1.0	-0.8	-3.8	-2.1	-1.9	-0.1	-0.8	-1.0	-0.6	-1.2
Hypothyroidism (self reported)	0.4	1.0	1.7	1.3	1.3	1.3	1.0	1.3	-1.0	1.0	0.7	-0.0	0.8	0.7
Ever had hysterectomy (womb removed)	0.4	0.5	1.5	1.2	1.0	-0.1	0.9	0.5	-0.1	-0.1	0.5	1.2	0.4	-0.0
Hand grip strength (right)	0.4	1.0	2.4	-1.1	0.2	1.5	-1.5	0.9	0.3	-1.2	0.2	1.6	0.2	0.2
Townsend deprivation index at recruitment	0.4	0.5	2.7	-0.6	1.2	-0.2	0.5	-0.4	-0.3	-0.6	-0.4	-0.1	-0.6	-1.6
Current tobacco smoking	0.4	0.7	2.4	0.1	1.1	0.5	1.6	0.2	-0.8	0.8	1.0	-0.4	0.9	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.2	-1.5	-0.4	-1.1	-1.2	-1.2	-0.1	-0.2	-1.2	-0.6	-1.0	-1.1
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.8	-0.8	0.1	-1.3	-1.2	0.2	1.1	-1.1	-1.0	0.0	-1.3	-0.3
Multivitamins +/- minerals	0.4	0.6	1.3	0.4	-1.0	-1.0	-1.2	-0.5	0.4	0.4	-0.7	-1.1	-0.7	0.1
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	3.2	-0.1	-1.8	0.5	-0.7	0.5	0.3	-0.2	-0.2	0.7	-0.1	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	2.7	-1.6	-1.2	-0.3	-1.5	-1.1	0.6	-0.5	-0.9	-0.3	-0.7	-1.0
Qualifications: None of the above	0.4	0.8	2.8	0.2	1.1	-1.7	1.0	-0.4	1.3	1.3	0.5	0.4	0.6	0.4
Financial difficulties in last 2 years	0.4	0.5	1.4	1.0	0.9	0.3	1.2	0.6	1.1	-0.4	0.5	0.5	0.6	0.3
Pain all over the body in last month	0.4	0.4	3.0	-0.1	0.5	0.5	-0.3	0.2	0.6	1.7	0.4	0.8	-0.0	0.1
Medication: Ramipril	0.4	0.5	2.3	-0.6	0.2	-0.1	1.0	0.3	0.4	1.5	-0.8	0.1	-0.6	-0.8
Impedance of arm (right)	0.4	1.9	4.5	2.1	-1.9	1.5	-0.2	1.5	0.2	-1.0	1.3	-0.3	1.1	2.0
Number of live births	0.4	0.6	3.0	0.5	1.7	0.7	0.5	0.2	-0.7	1.1	0.2	0.4	0.4	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.1	1.0	0.4	1.0	0.8	0.6	-0.3	-0.1	0.2	0.7	0.4	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.7	2.5	0.1	1.6	-0.6	1.5	0.4	0.3	-1.0	-0.5	-0.1	-0.7	-0.4
Peak expiratory flow (PEF)	0.4	0.8	2.2	-1.1	-1.1	-0.2	-0.2	0.3	-0.2	0.4	-1.2	1.5	-1.2	-1.1
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.2	0.4	0.9	-1.5	1.2	-0.2	-0.0	0.6	-0.2	-0.3	-0.3	-0.8
Loud music exposure frequency	0.4	0.4	1.1	-0.1	0.6	-1.0	1.1	0.4	0.6	-0.8	0.4	0.7	0.2	0.7
Forced vital capacity (FVC), Best measure	0.4	1.5	5.7	-0.1	-0.6	0.4	2.4	1.4	1.1	0.4	-0.7	2.3	-0.8	-0.7
Age at first live birth	0.4	0.8	2.3	-0.1	-0.8	1.0	0.4	0.3	-1.2	0.4	0.8	1.5	0.7	1.2
Eye problems/disorders: None of the above	0.4	0.5	1.1	-0.7	-0.4	-0.6	0.7	-0.6	0.2	0.7	-0.8	1.0	-0.8	-0.7
Angina (self-reported)	0.4	0.5	1.1	-0.9	-0.4	-1.1	-0.1	-1.0	0.3	-0.3	-1.0	-0.6	-0.7	-0.9
Medication: Omeprazole	0.4	0.5	2.0	0.2	0.9	-0.9	0.7	-0.3	-0.0	1.4	-0.3	-0.6	-0.7	-0.2
Leg pain on walking	0.4	0.5	3.0	-0.3	-1.0	0.1	-0.5	0.3	1.7	0.9	-0.5	0.4	-0.3	-0.0
Osteoarthritis (self-reported)	0.4	0.5	3.1	0.2	-0.0	-0.8	0.8	-0.6	1.8	0.2	0.3	0.9	0.3	-0.1
Medication: Gliclazide	0.4	0.4	1.7	0.2	-0.3	-0.2	0.5	-0.6	1.2	0.3	-0.6	-0.3	-0.4	-1.3
Illnesses of father: None of the above (group 1)	0.4	0.5	1.5	1.2	-0.1	0.7	1.0	1.1	0.2	-0.9	0.3	-0.1	0.3	0.5
Smoking status: Current	0.4	0.6	1.8	0.1	0.9	0.9	1.3	0.7	-0.3	-0.1	1.3	0.4	1.1	0.1
Hearing aid user	0.4	0.4	1.2	0.6	0.7	0.6	1.1	-0.2	0.4	1.1	0.7	-0.1	0.7	0.4
Medication: Bendroflumethiazide	0.4	0.6	2.5	0.8	0.2	0.8	0.2	0.8	-1.6	0.4	0.3	-0.2	0.5	1.1
Alcohol drinker status: Never	0.4	0.5	1.3	0.4	0.8	-0.8	-0.1	-1.0	0.8	1.1	-0.1	-0.9	-0.1	0.1
Pack years of smoking	0.4	0.6	2.2	0.9	0.1	-0.1	1.4	-0.2	0.0	0.8	-0.1	-1.5	-0.2	-1.1
Bipolar Disorder (2018)	0.3	0.4	2.7	-0.1	-0.4	-0.1	1.6	0.3	0.7	0.3	0.0	-0.9	-0.1	-0.4
Intelligence (Savage-Jansen 2018)	0.3	1.0	6.3	-0.9	-1.2	0.0	-0.2	-0.8	-0.5	-2.5	0.3	-0.8	0.3	-0.8
Alzheimer’s Disease (in father)	0.3	0.3	1.0	0.5	-0.4	0.7	0.1	1.0	-0.7	0.7	0.2	0.5	0.1	0.1
Major Depression (MDD)	0.3	0.3	1.2	-0.3	0.0	-0.5	1.1	-0.6	0.7	-0.1	0.1	-0.5	0.1	-0.9
Crohns Disease (2012)	0.3	0.5	1.8	-0.4	0.5	0.2	-1.2	-0.3	-1.3	0.2	-1.0	-0.3	-0.8	-0.7
Primary Biliary Cirrhosis	0.3	0.4	1.0	-0.4	-1.0	-0.6	0.7	-0.6	-0.3	-0.0	-0.6	-0.8	-0.6	-1.0
BMI	0.3	1.5	4.5	0.7	2.0	-0.9	2.1	-0.2	0.4	2.1	-0.3	-1.5	-0.5	-0.4
Lung FVC	0.3	1.4	6.8	-0.1	-0.3	0.1	2.0	1.5	0.1	-1.1	-0.1	2.6	-0.3	-1.0
Tanning	0.3	4.2	9.3	-2.6	-2.1	-1.8	-1.4	-2.7	-1.7	-0.2	-1.8	-1.8	-1.8	-3.0
Hand grip strength (left)	0.3	0.8	3.0	-0.9	-0.0	1.0	-1.3	0.9	0.6	-0.9	0.3	1.7	0.3	0.5
Systolic blood pressure, automated reading	0.3	0.8	2.2	-0.8	1.0	-1.2	-0.8	-1.5	-1.0	0.3	-0.9	-0.7	-0.6	-0.3
Angina	0.3	0.4	0.9	-0.9	-0.4	-0.9	-0.1	-0.9	0.2	-0.4	-0.9	-0.5	-0.5	-0.8
Vitamin and mineral supplements	0.3	0.4	2.7	-1.6	-0.2	0.5	-0.1	-0.3	0.2	-0.5	-0.2	0.9	0.0	-0.4
Had menopause	0.3	0.3	2.0	0.4	0.1	-0.2	-0.4	-0.3	-0.3	-0.5	0.3	1.4	0.3	0.8
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.5	0.1	0.6	-1.2	0.6	-0.3	0.5	-0.4	-0.5	-0.5	-0.6	-0.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.5	3.0	-0.3	0.1	-0.6	-1.7	0.3	-0.1	0.0	-0.5	0.7	-0.7	-0.4
Hip circumference	0.3	1.2	6.3	0.4	1.9	-0.2	2.5	1.0	1.2	0.3	-0.2	0.7	-0.3	0.6
Mouth/teeth dental problems: Dentures	0.3	0.5	1.4	0.6	-0.3	-1.2	1.0	-0.5	-0.0	-0.3	-0.7	-0.9	-0.7	-0.4
Gout (self-reported)	0.3	0.4	1.3	-0.3	0.3	1.0	-1.0	0.6	0.2	0.9	0.2	1.1	0.2	0.0
Medication: Amlodipine	0.3	0.4	2.4	0.2	1.6	-0.6	-0.4	-0.3	-0.8	0.1	-0.4	0.1	-0.3	-0.2
Leg fat percentage (right)	0.3	1.2	3.3	-0.6	1.1	-1.7	0.9	-0.6	0.1	1.6	-0.8	-1.8	-1.0	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	1.4	-0.2	-0.5	0.5	-0.5	1.2	-0.2	-0.3	0.2	0.7	0.3	0.8
Heart disease (mother)	0.3	0.4	0.7	-0.8	-0.3	-0.4	0.8	0.1	-0.6	0.7	-0.7	-0.2	-0.8	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	2.2	-0.1	-0.6	0.1	-0.3	-1.0	-1.5	-0.2	0.1	-0.0	0.0	-0.4
Illnesses of father: Heart disease	0.3	0.4	1.6	0.6	0.2	0.4	-0.9	0.8	1.3	-0.7	-0.3	-0.2	-0.3	0.6
Ever had bowel cancer screening	0.3	0.3	0.8	-0.4	0.7	-0.7	0.5	-0.1	0.2	-0.2	-0.7	0.5	-0.9	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.6	-1.3	0.2	-0.3	0.2	-0.3	0.1	-0.1	-0.4	-0.3	-0.5	-0.9
Qualifications: nursing, teaching	0.3	0.4	2.5	-0.1	-0.6	0.1	-0.7	0.2	-1.6	-0.8	-0.4	-0.4	-0.7	-0.0
Eye problems/disorders: Cataract	0.3	0.4	1.4	0.7	-1.2	0.5	-0.5	0.5	0.7	-0.4	0.2	-0.4	0.3	0.6
Medication for cholesterol	0.3	0.4	1.3	0.2	0.2	0.7	-0.9	0.4	0.9	0.1	0.5	0.3	0.4	1.2
Number of self-reported non-cancer illnesses	0.3	0.6	1.8	0.7	1.4	0.2	0.4	0.4	0.8	0.4	0.9	0.4	0.8	1.1
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.4	-1.2	0.3	0.2	0.5	0.9	0.7	-0.4	-0.2	0.9	-0.4	0.1
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.5	0.3	0.1	-0.5	-1.6	-0.3	0.3	-0.7	-0.6	-0.2	-0.5	-0.1
Leg fat percentage (left)	0.3	1.0	2.9	-0.6	0.9	-1.7	0.7	-0.6	0.5	1.2	-0.9	-1.5	-1.1	-0.4
Heart disease (siblings)	0.3	0.4	1.7	0.5	-1.3	-0.0	-0.2	-0.3	1.1	0.8	0.3	-0.7	0.3	-0.1
Crohns Disease (2017)	0.2	0.5	2.3	0.3	0.3	1.0	0.6	1.0	-1.5	0.0	-0.3	0.1	-0.4	-0.1
Irritable Bowel Disease (IBD)	0.2	0.5	2.3	-0.2	-0.4	-0.2	0.3	-0.1	-1.5	0.0	-0.7	-0.9	-0.8	-0.8
Mean Putamen Volume	0.2	0.2	1.3	-0.2	0.1	0.8	-0.1	0.2	-0.5	-1.1	-0.2	0.4	-0.0	-0.2
Blood White Count	0.2	1.2	3.0	0.7	1.1	-0.5	-1.7	-1.4	-0.9	-0.2	1.1	-1.4	1.3	0.4
Number of treatments/medications taken	0.2	0.4	1.5	0.6	1.2	-1.0	0.3	-0.4	0.3	0.3	0.0	-0.7	0.1	0.2
Average weekly spirits intake	0.2	0.3	0.9	0.9	0.4	-0.1	-0.2	-0.4	0.6	-0.2	0.6	-0.8	0.3	-0.4
Leg fat-free mass (left)	0.2	0.9	3.2	0.0	1.8	0.2	1.1	1.1	0.9	0.6	-0.4	1.6	-0.3	0.3
Body mass index (BMI)	0.2	0.9	3.4	-0.3	1.8	-1.3	1.3	-0.1	0.7	1.0	-0.6	-0.1	-0.7	-0.3
Leg predicted mass (left)	0.2	0.8	2.9	-0.0	1.7	0.2	1.1	1.0	0.9	0.6	-0.5	1.5	-0.4	0.3
Waist circumference	0.2	0.7	2.5	-0.6	0.1	-1.6	-0.4	-0.7	0.8	0.1	-1.1	-0.8	-1.1	-0.7
Mouth/teeth dental problems	0.2	0.4	1.7	-0.4	0.2	0.1	-1.1	-0.7	0.1	-1.3	0.2	-0.5	0.1	-0.4
Medication: Simvastatin	0.2	0.3	1.1	0.3	1.0	0.2	0.2	0.0	-0.5	1.0	-0.5	-0.5	-0.3	-0.2
Impedance of arm (left)	0.2	1.0	5.6	1.2	-2.4	0.7	-0.7	0.5	-0.0	-0.9	0.7	-0.7	0.6	1.0
Arm fat mass (right)	0.2	0.7	2.1	0.3	1.4	-0.8	1.4	0.7	0.9	1.0	-0.2	0.1	-0.3	0.5
Length of working week for main job	0.2	0.3	2.0	-0.0	-0.5	0.0	-0.2	-0.0	-0.1	-1.4	-0.2	-0.3	0.1	-0.7
Hair/balding pattern: Pattern 4	0.2	0.5	1.1	0.5	-0.0	-0.8	1.1	0.1	-1.0	-0.7	-0.8	-0.7	-0.7	-0.7
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.5	0.6	0.4	0.8	1.2	1.0	-0.7	0.6	0.5	-0.0	0.5	0.3
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.5	0.1	-0.5	0.5	0.6	-0.1	0.6	0.7	0.6	0.6	0.6	0.4
Medication: Allopurinol	0.2	0.3	0.9	-0.3	-0.4	-0.2	-0.8	-0.1	1.0	0.7	-0.4	0.7	-0.5	-0.5
Leg fat mass (right)	0.2	0.8	1.8	-0.4	1.2	-1.3	1.0	-0.1	0.7	1.4	-0.8	-0.9	-0.9	-0.3
Arm predicted mass (right)	0.2	0.9	4.0	-0.7	2.0	0.2	0.5	0.7	0.7	0.7	-0.2	1.8	-0.0	0.2
Comparative height size at age 10	0.2	1.1	5.0	0.5	2.2	0.3	0.7	0.8	-0.5	-1.7	0.1	1.1	-0.2	1.1
Supplements: Vitamin C	0.2	0.2	0.8	0.9	0.6	-0.4	0.2	-0.1	-0.5	0.1	-0.1	-0.4	-0.2	-0.5
Breast cancer (self-reported)	0.2	0.2	0.9	-0.1	1.0	-0.2	0.1	-0.5	0.2	0.0	-0.5	-0.7	-0.6	-0.6
Leg predicted mass (right)	0.2	0.9	3.8	0.1	1.4	0.2	0.9	1.1	1.2	0.0	-0.4	1.9	-0.3	0.3
Arm fat-free mass (left)	0.2	0.8	3.7	-0.5	1.9	0.1	1.1	0.9	0.8	0.5	-0.2	1.5	-0.1	0.2
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.6	-0.5	0.5	-0.4	0.7	0.3	-0.3	-0.5	-0.5	-0.1	-0.7	-0.2
Commuting to job workplace: Cycle	0.2	0.2	0.7	-0.6	-0.8	0.2	0.4	0.4	-0.3	-0.6	0.2	0.7	0.2	-0.1
Impedance of whole body	0.2	1.0	4.3	1.2	-2.1	0.8	-0.9	0.5	0.1	0.0	0.9	-1.0	0.7	1.1
Leg fat mass (left)	0.2	0.7	1.5	-0.4	1.1	-1.2	1.0	-0.0	0.9	1.2	-0.8	-0.6	-0.8	-0.3
Arm predicted mass (left)	0.2	0.8	3.6	-0.5	1.9	-0.1	1.1	0.7	0.8	0.4	-0.3	1.5	-0.2	0.2
Height	0.1	2.8	9.5	-0.3	0.4	2.0	-1.2	2.1	1.1	-1.7	1.2	3.1	1.4	1.9
Hair Pigment	0.1	2.0	4.7	-0.8	1.1	-2.2	-0.7	-2.1	-0.2	1.9	-1.3	-1.3	-1.4	-1.3
Impedance of leg (right)	0.1	0.7	3.2	0.2	-1.0	0.7	-0.5	0.1	-0.6	0.9	0.7	-1.8	0.5	0.5
Trunk fat percentage	0.1	0.5	1.3	0.7	0.6	-0.6	0.9	0.6	0.9	1.2	-0.0	-0.4	-0.2	0.7
Age when periods started (menarche)	0.1	0.3	1.0	0.6	0.7	0.5	0.6	0.6	-0.2	0.3	1.0	0.5	0.7	0.4
Sitting height	0.1	0.8	6.5	-0.4	0.0	0.0	-1.1	0.3	2.5	0.1	-1.0	0.4	-0.6	0.1
Impedance of leg (left)	0.1	0.6	2.7	0.2	-1.7	0.5	-0.9	0.0	0.3	0.4	0.5	-1.5	0.4	0.4
Trunk fat mass	0.1	0.4	0.8	0.2	0.8	-0.7	0.9	0.5	0.9	0.9	-0.3	-0.1	-0.5	0.5
Nervous feelings	0.1	0.2	0.6	-0.1	0.2	-0.5	0.6	-0.6	-0.7	-0.5	0.2	0.0	0.2	-0.1
Weight	0.1	0.6	2.0	-0.4	1.4	-0.8	0.9	0.5	1.0	0.4	-0.7	0.5	-0.7	0.1
Arm fat percentage (right)	0.1	0.5	1.4	0.7	1.2	-0.7	1.1	0.6	0.7	0.8	0.1	-0.4	-0.0	0.8
Trunk fat-free mass	0.1	0.6	2.9	-0.9	1.7	-0.1	0.8	0.5	0.5	-0.2	-0.6	1.1	-0.5	-0.0
Trunk predicted mass	0.1	0.6	2.3	-0.9	1.5	-0.1	0.8	0.6	0.5	-0.3	-0.6	1.1	-0.5	-0.0
Standing height	0.1	0.7	1.9	-0.3	-0.6	1.0	-0.7	1.3	0.8	-1.1	-0.2	1.4	-0.0	0.9
Body fat percentage	0.1	0.5	1.6	0.4	0.7	-0.9	0.8	0.3	0.8	1.3	-0.2	-0.6	-0.3	0.5
Arm fat-free mass (right)	0.1	0.7	3.0	-0.8	1.7	0.3	0.3	0.7	0.5	0.4	-0.3	1.7	-0.2	-0.0
Comparative body size at age 10	0.1	0.3	1.3	-0.2	-0.8	-0.6	-0.8	-1.1	0.4	-0.5	-0.0	0.1	0.0	-0.0
Whole body fat mass	0.1	0.6	1.6	0.1	1.1	-0.9	1.2	0.4	0.9	1.3	-0.4	-0.3	-0.6	0.2
Whole body fat-free mass	0.1	0.7	2.8	-0.5	1.7	0.1	0.9	0.8	0.8	0.1	-0.5	1.5	-0.4	0.2
Leg fat-free mass (right)	0.1	0.8	3.3	0.0	1.3	0.1	0.9	1.0	1.2	0.0	-0.5	1.8	-0.4	0.2
Arm fat percentage (left)	0.1	0.3	0.9	0.2	0.9	-0.9	0.8	0.3	0.6	0.9	-0.1	-0.4	-0.2	0.4
Whole body water mass	0.1	0.7	2.7	-0.6	1.6	0.1	0.9	0.9	0.7	0.1	-0.5	1.6	-0.4	0.2
Arm fat mass (left)	0.1	0.5	1.5	0.0	1.2	-0.9	1.2	0.4	0.7	0.6	-0.4	-0.1	-0.4	0.2
Medication: Atorvastatin	0.1	0.2	0.7	-0.1	0.1	-0.2	-0.4	-0.2	0.8	-0.8	0.3	-0.1	0.4	0.1
Basal metabolic rate	0.1	0.7	2.7	-0.5	1.6	-0.1	1.1	0.8	0.9	0.4	-0.5	1.3	-0.5	0.1

Hub : Genes

QSER1

Models

Trait associations