TWAS hub - RAB11FIP4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Nerve Tibial	0.494	0.0547	1.6e-14	0.311	NA	0.331	NA	0.316	1.8e-22	NA	4.7e-24	NA	7.7e-23
2	NTR	Blood	0.114	0.0224	0.0e+00	0.047	0.062	0.080	0.074	0.074	5.1e-15	2.2e-19	1.1e-24	7.2e-23	7.8e-23
3	YFS	Blood	0.155	0.0340	5.2e-12	0.061	0.051	0.087	0.077	0.073	2.7e-19	3.2e-16	5.9e-27	4.7e-24	6.6e-23

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Cholesterol lowering medication	6.3	9.2	13.5	1.9	3.3	3.7
Relative age of first facial hair	5.9	12.1	18.2	-1.5	-4.0	-4.3
Blood clot in the leg (DVT)	5.6	7.2	9.2	3.0	2.8	2.1
Deep venous thrombosis (DVT) (self-reported)	5.0	6.4	7.5	2.7	2.7	2.2
Qualifications: A levels/AS levels or equivalent	4.9	10.8	22.4	-0.4	-4.7	-3.1
Qualifications: College or University degree	4.6	14.4	26.8	-1.5	-5.2	-3.8
Height	4.3	83.3	148.8	-2.9	-12.2	-9.6
Had major operations	4.3	5.0	10.6	-3.3	-1.8	-1.0
Medication for cholesterol	4.3	6.6	10.8	-0.1	-3.0	-3.3
Eye problems/disorders: None of the above	4.2	4.9	11.1	3.3	1.1	1.5
Worry too long after embarrassment	4.0	6.7	7.7	-2.3	-2.8	-2.7
Chest pain or discomfort	4.0	5.8	7.7	1.5	2.8	2.7
Forced expiratory volume in 1-second (FEV1), predicted	3.7	7.7	8.7	-3.0	-2.9	-2.4
Hair/balding pattern: Pattern 4	3.6	8.8	14.7	3.8	2.3	2.5
Standing height	3.5	34.7	63.7	-1.8	-8.0	-6.1
Shortness of breath walking on level ground	3.5	4.2	6.8	0.1	2.6	2.4
Commuting to job workplace: Car/motor vehicle	3.5	4.0	7.5	0.1	2.7	2.1
Medication: Simvastatin	3.4	5.1	8.4	1.4	2.2	2.9
Schizophrenia vs Biploar Disorder	3.3	4.4	5.9	1.1	-2.4	-2.4
Pain all over the body in last month	3.1	3.3	6.3	2.5	1.6	1.0
Relative age voice broke	3.0	4.7	9.1	-0.5	-2.2	-3.0
Eye problems/disorders: Glaucoma	3.0	3.6	4.9	-2.2	-1.6	-1.8
Leg fat percentage (left)	2.9	10.3	17.2	1.0	4.2	3.6
Leg fat percentage (right)	2.8	10.0	17.2	1.0	4.2	3.4
Hand grip strength (right)	2.7	7.2	8.4	-2.9	-2.9	-2.3
Number of children fathered	2.7	3.1	6.2	-0.8	2.5	1.6
Reason for reducing amount of alcohol drunk: Health precaution	2.6	3.0	4.9	2.2	1.3	1.6
Overall health rating	2.6	5.5	8.9	0.4	3.0	2.8
Heel T-Score	2.5	19.6	32.9	-0.2	-5.1	-5.7
Diabetes (mother)	2.5	3.1	3.9	-2.0	-1.3	-1.9
Illnesses of father: None of the above (group 1)	2.5	3.0	3.9	-1.9	-2.0	-1.3
Age started oral contraceptive pill	2.5	3.1	8.5	2.9	0.8	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	2.4	5.5	7.6	-1.3	-2.8	-2.7
Length of working week for main job	2.4	2.7	7.2	-2.7	0.7	0.6
Breastfed as a baby	2.4	2.9	4.9	2.2	-1.2	-1.6
Current tobacco smoking	2.3	3.8	6.4	1.4	2.5	1.8
Age when periods started (menarche)	2.3	5.6	10.8	-0.3	-3.3	-2.4
Nervous feelings	2.3	4.2	5.1	-2.3	-2.1	-1.8
Had menopause	2.3	2.9	3.5	1.9	1.9	1.3
Wheeze or whistling in the chest in last year	2.3	4.0	5.9	0.5	2.4	2.4
Mouth/teeth dental problems: Mouth ulcers	2.3	3.7	4.2	-2.0	-1.9	-1.8
Heart disease (siblings)	2.3	2.8	6.2	2.5	1.1	1.0
Hearing difficulty/problems: Yes	2.2	3.3	6.0	0.9	2.4	1.8
Medication for hormone replacement therapy	2.2	2.4	3.9	-0.7	2.0	1.7
Smoking status: Current	2.2	3.5	5.6	1.6	2.4	1.6
Worry (Nagel 2018)	2.1	4.4	7.3	-2.7	-1.9	-1.5
Arm fat percentage (right)	2.1	8.5	13.8	1.6	3.7	3.0
Comparative height size at age 10	2.1	11.3	20.0	-0.6	-4.5	-3.7
Illnesses of father: Heart disease	2.1	3.0	4.1	1.9	2.0	1.1
Breast cancer (self-reported)	2.1	2.5	3.3	1.3	1.6	1.8
Heart disease (mother)	2.0	2.5	4.1	1.6	2.0	0.9
Arm fat percentage (left)	2.0	7.9	13.0	1.6	3.6	2.9
Qualifications: nursing, teaching	2.0	3.0	4.2	-0.9	-2.0	-2.1
High cholesterol (Self-reported)	2.0	3.5	7.2	-0.3	1.8	2.7
Neuroticism (Nagel 2018)	1.9	4.4	9.9	-3.2	-1.5	-1.0
LDL Cholesterol	1.9	3.1	3.3	1.8	1.7	1.7
Reaction Time	1.8	3.4	6.3	-0.2	-2.5	-1.9
Body mass index (BMI)	1.8	7.5	12.2	0.2	3.5	3.2
Alcohol drinker status: Previous	1.8	2.0	2.6	-1.4	1.2	1.6
Neuroticism	1.7	4.1	8.4	-2.9	-1.5	-1.2
Fed-up feelings	1.7	3.0	7.7	-2.8	-1.0	-0.6
Neuroticism score	1.7	3.6	7.3	-2.7	-1.4	-1.2
Birth weight of first child	1.7	3.2	4.9	-0.6	-2.1	-2.2
Body fat percentage	1.7	6.6	11.1	1.6	3.3	2.5
Medication: Allopurinol	1.7	2.2	4.7	0.0	1.4	2.2
Diabetes diagnosed by doctor	1.7	2.9	3.3	-1.8	1.8	1.4
Commuting to job workplace: Walk	1.7	1.9	3.1	0.8	-1.8	-1.4
Back pain experienced in last month	1.7	2.4	3.9	0.2	1.8	2.0
Number of self-reported non-cancer illnesses	1.7	2.9	6.1	0.1	1.6	2.5
Fasting Glucose	1.6	2.0	3.1	-0.9	-1.4	-1.8
Lung FEV1/FVC ratio	1.6	8.0	11.0	2.7	3.3	2.4
Medication: Levothyroxine sodium	1.6	2.7	4.5	0.3	2.1	1.9
Qualifications: NVQ or HND or HNC or equivalent	1.6	2.0	4.7	-2.2	1.1	-0.1
Average weekly red wine intake	1.6	2.3	6.7	2.6	0.1	0.5
Unable to work because of sickness or disability	1.6	2.1	3.2	0.2	1.7	1.8
Coronary Artery Disease (CAD)	1.5	1.8	3.6	1.9	1.2	0.5
Type 2 Diabetes (T2D) (2018)	1.5	2.8	7.5	-2.7	-0.1	-0.9
Father’s age at death	1.5	2.0	3.3	0.5	-1.8	-1.5
Medication: Lansoprazole	1.5	1.8	2.5	-1.4	-1.6	-0.9
Tinnitus: Yes, now most or all of the time	1.5	1.7	2.6	1.2	-1.6	-1.1
Bipolar Disorder (2018)	1.4	2.2	5.4	-2.3	0.9	0.6
Depressed Affect (Nagel 2018)	1.4	3.0	8.6	-2.9	0.1	0.5
Depression (Nagel 2018)	1.4	2.2	4.4	-0.8	1.2	2.1
Ovarian Cancer	1.4	1.9	3.5	-0.4	1.9	1.5
Bipolar Disorder (2011)	1.4	1.4	4.1	0.0	-2.0	0.0
Lung FVC	1.4	7.1	16.2	4.0	1.8	1.3
Average weekly fortified wine intake	1.4	1.6	1.9	1.4	-1.2	-1.2
Diverticular disease/diverticulitis (self-reported)	1.4	1.7	2.7	1.4	0.8	1.6
Diabetes (self-reported)	1.4	2.1	2.8	-1.5	1.7	1.2
Illnesses of siblings	1.4	2.0	3.6	-0.6	-1.4	-1.9
Trunk fat-free mass	1.4	8.1	13.5	-2.4	-3.7	-2.2
Trunk predicted mass	1.4	8.2	14.0	-2.3	-3.7	-2.3
Glaucoma (self-reported)	1.4	1.6	2.2	-1.5	-1.1	-1.2
Exposure to tobacco smoke outside home	1.4	1.9	2.8	1.1	-1.3	-1.7
Smoking Status	1.3	3.0	7.4	0.3	2.7	1.3
Heel bone mineral density (BMD) T-score, automated (right)	1.3	3.0	4.4	-0.9	-1.9	-2.1
Forced vital capacity (FVC), Best measure	1.3	4.8	7.7	0.4	-2.8	-2.6
Medication: Blood pressure	1.3	2.3	5.6	-2.4	-1.1	-0.3
Medication: Omeprazole	1.3	1.6	2.5	-1.1	1.6	1.1
Alcohol intake frequency.	1.3	2.9	8.4	-2.9	-0.6	-0.2
Wears glasses or contact lenses	1.3	1.5	2.4	-1.5	-0.9	-1.1
Supplements: Zinc	1.2	1.3	2.7	-0.1	1.6	1.1
Hair/balding pattern: Pattern 2	1.2	1.5	3.3	-1.0	-0.4	-1.8
Pulse rate	1.2	2.0	5.7	2.4	0.2	0.4
Pulse wave reflection index	1.2	1.4	3.3	-1.8	0.1	-1.0
Mother’s age at death	1.2	1.5	2.7	0.8	-1.1	-1.6
Pain type(s) experienced in last month: Hip pain	1.2	1.6	2.9	0.2	1.7	1.3
Neuroticism (2016)	1.1	1.6	4.2	-2.0	-0.6	-0.3
Number of treatments/medications taken	1.1	2.0	2.8	-1.7	0.9	1.5
Trunk fat percentage	1.1	4.5	6.7	1.9	2.6	1.7
Sitting height	1.1	8.0	13.3	-1.2	-3.6	-3.1
Medication: Ramipril	1.1	1.5	1.9	-1.4	1.2	1.0
Depression (self-reported)	1.1	1.3	3.8	-2.0	0.3	0.2
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	2.4	-0.3	-1.3	-1.6
Migraine (self-reported)	1.1	1.3	2.5	-1.6	-0.6	-1.1
Mean time to correctly identify matches	1.1	2.2	4.3	0.3	-2.1	-1.5
Ever had bowel cancer screening	1.1	1.3	2.6	1.6	0.7	1.0
Medication: Blood pressure	1.1	2.2	3.8	0.0	1.6	2.0
Crohns Disease (2017)	1.0	2.2	3.2	-1.5	-1.0	-1.8
Hand grip strength (left)	1.0	2.7	4.6	-1.6	-2.1	-0.8
Ever used hormone-replacement therapy (HRT)	1.0	1.3	1.8	0.6	1.3	1.3
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.1	1.1	1.4	0.1
Asthma	1.0	1.9	3.1	0.2	1.6	1.8
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	2.6	1.5	1.6	1.0
Arm predicted mass (right)	1.0	5.0	7.3	-2.2	-2.7	-1.7
Whole body fat-free mass	1.0	5.6	9.4	-2.0	-3.1	-1.8
Friendships satisfaction	1.0	1.2	2.9	-1.7	-0.6	-0.6
Osteoarthritis (self-reported)	1.0	1.2	3.1	-0.4	-1.8	-0.7
Whole body water mass	1.0	5.7	9.3	-2.1	-3.0	-1.8
Average weekly champagne plus white wine intake	1.0	1.4	2.0	1.4	1.4	0.7
Risk taking	1.0	1.4	3.2	1.8	0.9	0.6
Alzheimer’s Disease (in mother)	0.9	1.1	3.0	1.7	-0.1	-0.4
Crohns Disease (2012)	0.9	1.5	1.8	-1.3	-1.0	-1.4
BMI	0.9	5.1	8.8	-0.6	3.0	2.5
Cardiovascular Disease	0.9	3.0	4.8	-1.3	1.6	2.2
Average weekly spirits intake	0.9	1.1	2.0	-0.1	1.2	1.4
Pack years adult smoking proportion	0.9	1.3	1.9	1.4	1.1	0.9
Forced vital capacity (FVC)	0.9	3.6	6.7	0.6	-2.6	-1.9
Mouth/teeth dental problems	0.9	1.3	2.0	0.4	1.4	1.3
Time employed in main current job	0.9	1.1	1.5	-1.2	-0.9	-0.9
Prospective memory result	0.9	1.1	1.3	-1.0	-1.1	-1.0
Headache pain in last month	0.9	1.5	2.2	-1.5	1.1	1.0
High blood pressure (siblings)	0.9	1.3	2.9	-0.4	0.9	1.7
Arm fat-free mass (right)	0.9	4.6	6.9	-2.1	-2.6	-1.6
Number of full brothers	0.9	1.1	1.2	1.1	1.1	1.0
Emphysema/chronic bronchitis	0.9	1.0	1.2	-0.9	-1.0	-1.1
Angina (self-reported)	0.9	1.2	1.9	1.0	0.9	1.4
Leg fat mass (right)	0.9	3.6	5.6	0.2	2.4	2.3
Asthma (self-reported)	0.9	1.9	3.1	-0.1	1.6	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.8	4.9	2.2	0.7	0.2
Miserableness	0.9	1.6	4.5	-2.1	-0.5	-0.2
Medication: Lisinopril	0.9	1.2	2.8	-0.6	0.7	1.7
Myopia	0.9	1.3	2.8	1.7	0.1	1.1
Vascular/heart problems diagnosed by doctor	0.9	2.3	3.5	0.8	-1.7	-1.9
Heart attack/myocardial infarction (self-reported)	0.9	1.2	1.9	0.4	1.4	1.2
Pack years of smoking	0.9	1.3	1.9	1.4	1.1	1.0
Leg fat mass (left)	0.9	3.6	5.3	0.1	2.3	2.3
Major Depression (MDD)	0.8	1.0	3.0	-1.7	0.0	0.0
Primary Biliary Cirrhosis	0.8	1.1	1.1	-1.0	1.0	1.1
Type 2 Diabetes (T2D) (2012)	0.8	0.9	1.7	-0.7	1.3	0.8
Sensitivity / hurt feelings	0.8	1.3	1.5	-1.2	-1.1	-1.2
Angina	0.8	1.0	1.3	1.1	0.7	1.2
Maternal smoking around birth	0.8	1.2	2.8	0.5	1.7	0.6
Qualifications: CSEs or equivalent	0.8	1.0	2.9	-1.7	-0.3	-0.3
Waist circumference	0.8	2.8	4.8	0.5	2.2	1.8
Had other major operations	0.8	0.9	1.4	-0.8	1.2	0.9
Financial difficulties in last 2 years	0.8	1.1	2.9	-1.7	0.3	0.5
Heart attack	0.8	1.0	1.7	0.5	1.3	1.1
Mouth/teeth dental problems: Loose teeth	0.8	1.0	2.7	1.6	0.5	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	1.3	0.8	1.0	1.1
Mood swings	0.8	1.5	4.2	-2.0	0.4	0.3
Mineral and other dietary supplements	0.8	1.1	1.4	1.2	1.1	0.9
Hearing aid user	0.8	1.0	1.5	1.1	1.2	0.4
Irritability	0.8	1.3	1.8	-1.3	1.2	0.7
Pain experienced in last month	0.8	1.4	1.9	-0.8	-1.3	-1.4
Intelligence (Savage-Jansen 2018)	0.7	2.3	3.8	-0.5	-2.0	-1.7
Body Mass Index (BMI) (2010)	0.7	0.9	2.4	-1.5	0.5	0.4
Mean Putamen Volume	0.7	0.8	1.7	-0.1	0.8	1.3
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.1	-1.1	0.9	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.2	-0.1	0.7	1.5
High blood pressure	0.7	2.1	2.5	-1.4	1.3	1.6
Supplements: Glucosamine	0.7	1.0	1.6	-0.8	-1.3	-0.7
Arm fat mass (right)	0.7	3.0	4.6	0.6	2.1	2.0
Loud music exposure frequency	0.7	0.8	2.3	-1.5	-0.1	0.4
Chronic bronchitis/emphysema (mother)	0.7	0.9	1.4	-1.0	-0.4	-1.2
Knee pain experienced in last month	0.7	1.1	1.9	-1.4	-1.0	-0.7
Guilty feelings	0.7	1.0	2.5	-1.6	-0.4	-0.7
Basal metabolic rate	0.7	3.7	5.8	-1.8	-2.4	-1.4
Arm predicted mass (left)	0.7	3.8	5.1	-2.2	-2.3	-1.2
Schizophrenia (2018)	0.6	1.1	2.9	1.7	-0.5	0.5
Vitamin and mineral supplements	0.6	0.9	1.4	1.1	-0.3	-1.2
Medication: Metformin	0.6	0.8	1.2	-1.1	1.1	0.2
Diabetes (father)	0.6	0.8	1.2	-0.4	-1.1	-1.0
Severe depression (siblings)	0.6	0.7	1.9	-1.4	-0.4	0.1
Stomach or abdominal pain in last month	0.6	0.7	1.3	-0.1	1.1	0.9
Medication: Atenolol	0.6	0.7	1.2	-0.9	0.3	1.1
Impedance of arm (right)	0.6	2.6	6.7	2.6	-0.5	-0.9
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	1.7	0.3	1.1	1.3
Noisy workplace	0.6	0.7	1.1	0.7	0.7	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	2.3	1.2	-1.4	-1.5
Impedance of arm (left)	0.6	2.9	5.6	2.4	-0.8	-1.6
Ever highly irritable/argumentative for 2 days	0.6	0.8	1.2	-0.8	0.7	1.1
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	2.3	1.5	0.8	-0.1
Age at first live birth	0.6	1.0	2.6	-0.5	-1.6	0.2
Pulse wave peak to peak time	0.6	0.7	1.2	0.8	-1.1	-0.4
Medication for pain relief, constipation, heartburn	0.6	1.1	2.6	1.6	-0.8	0.1
Whole body fat mass	0.6	2.4	3.8	0.7	2.0	1.7
Number of full sisters	0.6	0.7	1.3	0.1	1.1	0.9
Supplements: Vitamin C	0.6	0.7	1.4	-1.2	-0.8	-0.4
Smoking status: Previous	0.6	0.9	1.4	-0.6	-1.0	-1.2
Arm fat mass (left)	0.6	2.6	4.3	0.6	2.1	1.8
Commuting to job workplace: Public transport	0.6	0.7	1.0	-0.6	-0.8	-1.0
Illnesses of father: High blood pressure	0.6	0.7	1.2	-0.9	0.3	1.1
Arm fat-free mass (left)	0.6	3.2	4.4	-2.0	-2.1	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	1.5	-1.2	0.7	0.5
Supplements: Calcium	0.6	0.7	1.8	-1.4	0.0	0.4
Triglycerides	0.5	0.9	1.6	-0.8	0.7	1.2
Blood Eosinophil Count	0.5	3.5	6.0	1.0	2.4	1.8
Medication: Co-codamol	0.5	0.6	1.2	-1.1	0.7	0.1
Neck or shoulder pain in last month	0.5	0.7	1.1	-0.7	1.1	0.6
Medication: Seretide 50 evohaler	0.5	0.6	1.7	-1.3	0.2	0.4
Hypertension (Self-reported)	0.5	1.5	2.3	-1.5	0.9	1.2
Leg fat-free mass (right)	0.5	2.6	4.4	-1.5	-2.1	-1.1
Eye problems/disorders: Cataract	0.5	0.6	0.9	-0.9	-0.7	-0.6
Leg predicted mass (right)	0.5	2.6	4.5	-1.5	-2.1	-1.1
Supplements: Fish oil (including cod liver oil)	0.5	0.6	1.0	-0.5	-0.8	-1.0
Number of operations (self-reported)	0.5	0.8	2.4	-1.5	0.1	0.1
Average weekly beer plus cider intake	0.5	0.8	1.2	1.0	-0.4	1.1
Rheumatoid Arthritis	0.4	0.6	1.2	-0.6	0.5	1.1
Ulcerative Colitis	0.4	0.6	0.9	-0.1	0.9	0.9
Blood Platelet Count	0.4	5.2	14.2	3.8	1.1	-0.3
Hypothyroidism (self reported)	0.4	0.9	1.3	0.7	1.1	0.9
Leg fat-free mass (left)	0.4	2.2	3.6	-1.4	-1.9	-1.1
Taking other prescription medications	0.4	0.6	1.7	0.0	0.3	1.3
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.3	1.1	-0.3	0.1
Multivitamins +/- minerals	0.4	0.5	0.7	-0.8	0.2	0.9
Leg predicted mass (left)	0.4	2.0	3.4	-1.3	-1.9	-1.0
Trunk fat mass	0.4	1.7	2.4	1.1	1.5	1.2
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	1.4	-0.7	-1.2	-0.4
Fluid intelligence score	0.4	0.8	1.2	-0.5	-0.9	-1.1
Hair/balding pattern: Pattern 3	0.4	0.7	1.3	-0.7	0.4	1.1
Happiness	0.4	0.4	1.1	-1.1	-0.3	0.3
Medication: Cholesterol lowering	0.4	0.7	1.6	-0.4	0.5	1.2
Tense / ‘highly strung’	0.4	0.6	1.1	-1.0	-0.5	-0.7
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	1.1	0.6	-1.1	-0.7
Medication: Amlodipine	0.4	0.6	1.5	-1.2	0.4	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.0	-0.5	-1.0	-0.3
Health satisfaction	0.4	0.5	1.3	-1.1	-0.2	0.4
Suffer from ‘nerves’	0.4	0.6	1.7	-1.3	-0.2	-0.3
Leg pain on walking	0.4	0.6	1.3	-1.1	-0.4	-0.5
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.1	-1.0	0.5	0.6
Loneliness, isolation	0.4	0.5	1.4	-1.2	-0.3	0.2
Long-standing illness, disability or infirmity	0.4	0.6	1.7	-1.3	0.0	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	1.1	-1.0	0.3	-0.2
Financial situation satisfaction	0.4	0.5	0.6	-0.6	0.8	0.7
Medication: Paracetamol	0.4	0.5	0.8	-0.9	-0.3	-0.9
Ever depressed for a whole week	0.4	0.5	1.0	1.0	-0.4	-0.4
Impedance of whole body	0.4	2.2	4.1	2.0	-0.7	-1.4
Alzheimer’s Disease (including proxy)	0.3	0.4	1.2	1.1	0.4	-0.0
Irritable Bowel Disease (IBD)	0.3	0.7	1.4	-1.2	-0.4	-0.8
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.0	-1.0	-1.0	-0.6
Age at First Birth	0.3	0.5	1.3	-0.0	-1.1	-0.4
Respiratory disease	0.3	0.6	0.9	-0.2	0.9	0.9
Systolic blood pressure, automated reading	0.3	0.9	2.5	-0.0	1.6	0.3
Townsend deprivation index at recruitment	0.3	0.5	1.3	-0.0	-1.2	-0.2
Serious illness, injury or assault to yourself	0.3	0.4	1.1	1.0	-0.2	0.2
Worrier / anxious feelings	0.3	0.6	1.0	-1.0	-0.7	-0.4
Number of live births	0.3	0.4	0.9	0.4	1.0	-0.0
Forced expiratory volume in 1-second (FEV1)	0.3	1.0	1.8	1.4	-0.8	-0.7
Pulse wave Arterial Stiffness index	0.3	0.4	0.8	-0.9	0.5	-0.1
Medication: Paracetamol	0.3	0.5	0.9	-0.7	1.0	-0.3
Gout (self-reported)	0.3	0.5	1.2	0.2	0.4	1.1
Pulse rate, automated reading	0.3	0.8	1.6	0.6	0.7	1.2
Family relationship satisfaction	0.3	0.4	0.4	0.7	-0.6	-0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.2	-0.1	-1.1	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	1.1	1.0	0.3	0.2
Medication: Atorvastatin	0.3	0.3	0.4	-0.7	0.5	0.6
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.6	-0.8	0.0	0.5
Diastolic blood pressure, automated reading	0.3	1.0	1.5	1.0	-0.8	-1.2
Alzheimer’s Disease (in father)	0.2	0.2	0.6	-0.0	0.7	-0.1
Schizophrenia (2014)	0.2	0.5	1.0	1.0	-0.4	0.7
Blood Red Count	0.2	1.6	2.0	1.3	-1.0	-1.4
Waist Hip Ratio (WHR)	0.2	1.0	2.2	1.5	0.8	0.1
Chronotype (morning person)	0.2	0.4	1.0	0.2	0.4	-1.0
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.5	-0.1	0.7	0.7
Ever had hysterectomy (womb removed)	0.2	0.2	0.5	0.7	0.4	-0.1
Impedance of leg (right)	0.2	0.7	1.4	0.6	-0.6	-1.2
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.3	-0.5	0.5	0.1
High blood pressure (mother)	0.2	0.3	0.8	0.1	-0.9	-0.3
Number of incorrect matches in round	0.2	0.4	1.1	-0.1	-0.2	-1.1
Qualifications: None of the above	0.2	0.4	1.0	0.3	1.0	0.3
Age at last live birth	0.2	0.3	0.3	-0.6	-0.5	0.5
Illnesses of siblings: Diabetes	0.2	0.3	0.4	-0.6	0.6	0.2
Osteoporosis (self-reported)	0.2	0.2	0.4	0.7	-0.5	0.1
Medication: Bendroflumethiazide	0.2	0.3	0.7	0.3	0.4	0.9
Alcohol drinker status: Never	0.2	0.2	0.6	-0.8	-0.2	-0.1
Commuting to job workplace: Cycle	0.2	0.3	0.7	0.2	-0.8	-0.3
Basal cell carcinoma (self-reported)	0.2	0.2	0.5	0.7	0.2	-0.1
Prostate Cancer	0.1	0.2	0.4	0.6	0.1	-0.4
HbA1C	0.1	0.1	0.2	0.4	0.0	0.2
HDL Cholesterol	0.1	0.2	0.5	0.7	0.1	0.3
Lupus	0.1	0.2	0.3	-0.5	0.3	-0.5
Blood White Count	0.1	0.4	0.8	0.0	0.7	0.9
Systolic Blood Pressure	0.1	0.7	1.7	-0.4	1.3	0.5
Allergy or Eczema	0.1	0.4	0.7	-0.8	-0.6	-0.2
Tanning	0.1	1.5	4.0	2.0	0.4	0.5
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.2	-0.4	0.1	0.3
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.5	-0.6	-0.7	-0.2
Chronic bronchitis/emphysema (father)	0.1	0.2	0.3	0.5	-0.5	0.1
Impedance of leg (left)	0.1	0.6	0.9	0.7	-0.7	-1.0
Alcohol usually taken with meals	0.1	0.1	0.2	-0.4	-0.3	0.1
Hearing difficulty/problems with background noise	0.1	0.2	0.4	0.4	0.1	0.6
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.2	0.1	-0.4	-0.4
Allergy	0.1	0.2	0.3	-0.4	-0.5	-0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.1	-0.3	-0.3	0.3
Hip circumference	0.1	0.4	1.1	-1.1	0.1	-0.2
Alcohol intake versus 10 years previously	0.1	0.1	0.1	0.1	-0.3	0.4
Falls in the last year	0.1	0.2	0.3	0.2	0.5	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.2	-0.2	0.5	-0.2
Lung cancer (father)	0.1	0.1	0.2	-0.5	-0.3	-0.3
Illnesses of mother	0.1	0.2	0.4	0.1	0.4	0.6
Exposure to tobacco smoke at home	0.1	0.1	0.2	-0.1	-0.5	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.5	0.3	0.1	0.7
Peak expiratory flow (PEF)	0.1	0.1	0.4	0.6	0.1	0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.3	0.5	-0.0	0.2
Birth weight	0.1	0.3	0.6	-0.2	-0.8	-0.3
Comparative body size at age 10	0.1	0.3	0.9	1.0	-0.1	0.1
Medication: Ibuprofen	0.1	0.2	0.4	-0.2	0.6	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.4	0.6	0.1	-0.2
Medication: Aspirin	0.1	0.2	0.4	0.0	0.4	0.6
Medication: Gliclazide	0.1	0.1	0.1	0.3	0.3	0.1
Ever taken oral contraceptive pill	0.1	0.1	0.3	-0.3	0.1	0.6
Fractured/broken bones in last 5 years	0.1	0.1	0.3	0.3	-0.0	-0.5
Bipolar Disorder or Schizophrenia	0.0	0.0	0.1	-0.2	0.1	0.3
Ulcerative Colitis (UC)	0.0	0.0	0.0	-0.1	-0.0	-0.1
Breast Cancer	0.0	0.1	0.1	0.3	0.4	-0.3
Hair Pigment	0.0	0.6	0.9	-0.9	0.9	0.4
Past tobacco smoking	0.0	0.0	0.1	0.3	-0.2	0.1
Weight	0.0	0.2	0.4	-0.6	-0.2	0.4
Mouth/teeth dental problems: Dentures	0.0	0.1	0.2	0.1	-0.4	-0.1
Medication: Aspirin	0.0	0.0	0.1	-0.2	0.1	0.3
Ever smoked	0.0	0.1	0.1	-0.4	-0.1	-0.2

Hub : Genes

RAB11FIP4

Models

Trait associations