Hub : Genes

RAB17

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3590	0.0470	1.6e-15	0.180	0.177	0.261	0.253	0.264	2.0e-21	5.5e-21	1.3e-31	1.4e-30	4.5e-32
2	GTEx	Esophagus Mucosa	0.2750	0.0610	7.2e-07	0.114	NA	0.216	NA	0.183	4.7e-08	NA	1.7e-14	NA	2.5e-12
3	NTR	Blood	0.0232	0.0104	7.7e-03	0.000	0.007	0.001	0.007	0.001	4.2e-01	1.9e-03	9.8e-02	1.6e-03	1.8e-01
4	ROSMAP	Brain Pre-frontal Cortex	0.3405	0.0481	4.3e-14	0.132	0.171	0.196	0.195	0.171	1.5e-16	2.1e-21	1.2e-24	1.5e-24	2.3e-21
5	TCGA	Breast Invasive Carcinoma	0.0168	0.0082	4.4e-03	-0.001	0.007	-0.001	NA	-0.001	4.7e-01	1.1e-02	7.4e-01	NA	7.4e-01
6	TCGA	Colon Adenocarcinoma	0.1070	0.0480	1.5e-03	0.057	0.045	0.097	NA	0.109	3.1e-04	1.2e-03	3.0e-06	NA	7.3e-07
7	TCGA	Glioblastoma Multiforme	0.2820	0.1170	6.7e-03	0.006	0.078	0.009	NA	-0.004	2.1e-01	2.2e-03	1.7e-01	NA	4.7e-01
8	TCGA	Head and Neck Squamous Cell Carcinoma	0.0680	0.0276	7.4e-05	0.060	0.053	0.044	NA	0.051	2.5e-07	1.4e-06	9.3e-06	NA	2.2e-06
9	TCGA	Kidney Renal Clear Cell Carcinoma	0.0956	0.0308	2.1e-07	0.047	0.057	0.041	NA	0.049	5.0e-06	4.8e-07	2.0e-05	NA	3.4e-06
10	TCGA	Brain Lower Grade Glioma	0.0293	0.0150	7.2e-03	0.006	0.018	0.003	NA	0.004	6.8e-02	3.5e-03	1.5e-01	NA	1.1e-01
11	TCGA	Lung Squamous Cell Carcinoma	0.0592	0.0235	3.1e-05	0.010	0.029	0.036	NA	0.033	2.3e-02	3.0e-04	5.4e-05	NA	1.2e-04
12	TCGA	Prostate Adenocarcinoma	0.0401	0.0214	9.1e-03	0.008	0.015	0.010	NA	0.006	4.2e-02	9.8e-03	2.9e-02	NA	6.5e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Bipolar Disorder (2018)	0.7	1.1	3.7	-0.3	1.3	-0.8	-0.8	1.7	0.5	-1.3	-0.1	0.8	-1.9	0.6	1.0
Bipolar Disorder or Schizophrenia	0.5	1.3	3.0	-1.5	1.2	0.1	-1.3	1.4	1.4	-1.7	1.0	0.3	-1.2	0.6	0.6
Depressed Affect (Nagel 2018)	0.3	0.5	2.5	-0.1	-0.2	-1.0	0.7	0.2	-0.5	-1.1	0.2	-0.9	0.1	0.0	1.6
Depression (Nagel 2018)	0.6	0.8	3.3	-0.6	0.7	0.3	-1.0	0.6	0.6	-1.7	0.3	-1.0	0.2	-0.5	1.8
Intelligence (Savage-Jansen 2018)	0.7	2.3	4.9	1.8	-1.5	0.6	2.1	-2.1	-1.4	1.4	-0.9	1.0	2.2	-0.4	-1.3
Neuroticism (Nagel 2018)	0.3	0.6	3.6	0.2	-0.4	-1.9	0.4	0.5	-0.5	-0.9	-0.1	-0.9	0.5	-0.0	0.9
Schizophrenia (2018)	0.4	0.9	3.1	-1.8	0.6	0.8	-1.1	0.4	1.5	-1.2	1.3	-0.2	0.0	0.4	-0.1
Schizophrenia vs Biploar Disorder	0.4	0.5	1.7	-0.5	-0.7	0.7	0.0	-0.5	-0.1	-0.1	0.9	-1.3	-0.4	0.2	-1.3
Worry (Nagel 2018)	0.2	0.4	3.0	0.7	-0.2	-1.7	0.4	0.1	-0.6	-0.6	-0.4	-0.3	0.2	0.2	-0.2
Alzheimer’s Disease (in mother)	0.4	0.5	1.9	0.5	-0.0	-0.8	0.1	-0.3	-0.6	-0.1	-1.0	1.4	1.1	-0.6	-0.1
Alzheimer’s Disease (in father)	1.0	1.1	7.6	0.4	0.5	1.3	0.2	0.0	-0.5	0.4	-0.9	2.8	1.1	-0.7	0.3
Alzheimer’s Disease (including proxy)	1.5	2.2	9.9	1.2	-0.6	-0.6	0.5	-1.0	-1.4	0.9	-1.9	3.1	1.9	-1.4	-1.0
Crohns Disease (2017)	1.1	2.4	4.5	1.2	-1.6	-2.1	0.4	-2.1	-1.7	1.4	-1.2	1.7	1.1	-1.8	-1.6
Irritable Bowel Disease (IBD)	1.1	2.7	4.8	1.4	-1.3	-1.6	1.1	-1.7	-1.4	1.8	-1.2	2.2	2.1	-1.9	-1.4
Ulcerative Colitis (UC)	0.8	1.5	6.0	0.9	-0.7	-0.8	0.8	-1.0	-0.5	1.6	-0.3	1.4	2.4	-1.2	-1.4
Major Depression (MDD)	0.7	0.8	5.8	0.0	0.6	-0.2	-1.0	-0.9	0.0	-0.1	-0.3	0.7	1.2	-2.4	0.1
Reaction Time	0.2	0.5	2.2	0.0	0.0	-1.0	0.0	-0.3	0.3	1.5	0.1	-0.6	0.0	-1.2	-0.6
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.7	0.5	-0.6	1.3	1.3	-1.0	-0.4	0.1	0.2	-0.0	0.8	0.4	-0.6
Breast Cancer	0.9	2.2	7.4	-0.2	0.9	2.7	-0.5	1.5	0.9	-1.5	0.2	-1.9	-1.9	0.8	2.0
Ovarian Cancer	2.4	3.2	8.3	2.9	-1.9	-0.6	1.7	-1.3	-2.6	1.9	-2.1	1.2	-0.6	-2.2	0.3
Prostate Cancer	1.8	2.6	11.2	-1.0	-0.9	-2.2	0.3	-0.1	0.9	0.4	0.5	-0.6	3.1	1.2	-3.3
Age at First Birth	0.5	0.7	2.7	0.2	-0.7	-1.6	0.6	-0.5	-0.2	0.0	-0.5	-0.1	1.2	-0.9	-1.2
Bipolar Disorder (2011)	0.5	0.5	1.1	0.6	-0.1	0.1	-1.1	-0.2	-0.4	-0.4	-1.0	0.6	-1.0	-0.8	0.8
Body Mass Index (BMI) (2010)	0.7	0.9	1.8	-1.1	0.9	-1.3	-1.1	1.1	1.0	-1.0	0.9	-0.0	-0.6	1.2	-0.3
Coronary Artery Disease (CAD)	0.6	0.8	2.6	-0.6	0.7	-1.1	-1.1	0.3	0.4	0.7	0.8	-1.6	-1.0	0.7	0.5
Crohns Disease (2012)	0.7	1.1	2.4	0.8	-0.8	-1.2	-0.6	-1.6	-0.7	1.3	-0.4	1.1	0.0	-1.4	-1.4
Mean Putamen Volume	0.5	0.6	2.2	-0.6	0.7	-0.2	-0.4	0.9	0.8	1.5	0.9	-1.0	0.1	0.4	0.2
Fasting Glucose	0.3	0.3	0.9	0.5	-0.2	0.4	0.0	-0.8	-0.6	0.7	0.3	-1.0	-0.1	-0.9	-0.6
HbA1C	1.2	1.3	6.6	-0.5	1.3	-0.6	-1.2	1.1	-0.1	-1.1	-0.4	1.2	-1.1	0.2	2.6
HDL Cholesterol	0.5	0.8	3.8	0.2	0.5	0.6	1.1	0.1	0.5	-0.5	0.4	-1.4	-2.0	-0.0	1.1
LDL Cholesterol	0.9	1.5	3.5	-1.8	1.1	-0.9	-1.2	0.9	1.7	-0.9	1.9	-1.0	-0.6	1.2	-0.3
Lupus	1.3	2.0	4.8	2.2	-1.0	1.3	1.8	-1.1	-1.7	1.0	-2.0	1.3	1.0	-1.3	0.1
Neuroticism (2016)	0.3	0.5	4.0	0.2	-0.2	-2.0	0.7	0.2	0.3	0.1	-0.5	-0.8	0.4	0.5	0.1
Primary Biliary Cirrhosis	0.7	1.1	8.3	0.2	-0.0	-2.9	-0.2	0.4	-0.0	0.9	-0.1	-0.0	-1.7	0.8	0.3
Rheumatoid Arthritis	1.0	1.4	2.5	-1.3	1.4	-0.8	-1.3	1.1	1.4	-0.9	1.6	-1.0	-1.3	1.2	0.8
Schizophrenia (2014)	0.5	1.2	2.8	-1.5	1.1	0.5	-1.0	1.3	1.6	-0.4	1.7	-0.4	-0.8	1.1	0.2
Triglycerides	1.0	1.6	3.2	-1.2	1.2	-0.9	-1.3	1.8	1.4	0.9	1.7	-1.5	0.3	1.5	-0.5
Type 2 Diabetes (T2D) (2012)	1.4	1.6	4.0	-0.8	1.4	0.1	-2.0	1.1	0.8	-0.3	1.3	-1.3	-1.8	0.9	2.0
Ulcerative Colitis	0.3	0.5	1.7	0.5	-0.1	-1.3	-0.1	-0.1	0.1	1.2	-0.0	0.9	0.8	-0.6	-0.9
Blood Eosinophil Count	0.1	1.0	5.2	0.1	-0.3	-1.6	0.2	-0.5	-0.4	-1.8	0.3	0.2	-0.6	-0.4	2.3
Blood Platelet Count	0.1	1.2	4.8	-0.6	1.0	2.2	0.6	0.5	0.8	1.8	1.0	-0.7	0.6	0.1	-1.3
Blood Red Count	0.1	1.1	5.0	-0.5	1.1	-0.1	-0.8	0.5	0.7	-2.2	0.1	0.1	-1.4	-0.5	1.8
Blood White Count	0.4	3.1	15.5	-0.2	1.4	-1.1	-1.1	0.7	1.1	-0.7	0.6	-0.9	-3.9	1.2	3.5
Heel T-Score	1.0	8.0	36.2	-0.8	3.2	1.3	-1.9	3.0	0.9	-2.1	2.3	0.3	-4.8	0.6	6.0
BMI	0.3	1.6	7.2	1.4	-0.6	0.8	0.2	-0.9	-0.9	0.1	-1.5	0.9	-1.1	-1.7	2.7
Height	0.4	7.4	27.0	2.5	-0.2	5.2	1.4	-0.8	-2.8	1.4	-1.6	3.8	-1.6	-3.6	3.2
Waist Hip Ratio (WHR)	0.3	1.3	3.6	1.6	-0.5	0.8	1.0	-0.2	-1.9	0.3	-1.7	-0.4	-0.9	-0.8	1.7
Systolic Blood Pressure	0.3	1.6	7.2	-0.4	-0.2	2.7	-0.2	-1.0	0.6	0.1	1.7	-2.1	-1.3	0.6	-0.9
Smoking Status	0.6	1.4	5.6	-0.3	1.0	-1.2	0.1	1.1	0.8	-0.1	1.1	-0.8	-1.7	2.4	1.4
Allergy or Eczema	0.2	0.4	1.2	-0.8	-0.3	-0.0	-0.4	-0.3	0.6	-0.5	1.0	-1.1	0.6	0.5	-0.6
Cardiovascular Disease	0.3	1.1	4.9	0.6	-0.5	-1.7	-0.9	-0.4	0.0	-0.9	-0.4	0.3	-1.5	-0.0	2.2
Hypothyroidism (self reported)	0.3	0.7	4.8	0.9	-0.8	-2.2	0.4	-0.1	-0.3	0.2	-0.9	0.6	0.0	-0.8	-0.6
Respiratory disease	0.9	2.0	5.9	1.7	-1.5	-2.4	1.3	-1.3	-1.7	0.8	-1.5	1.2	0.7	-1.2	-0.6
Type 2 Diabetes (T2D) (2018)	0.4	0.8	2.7	0.9	-1.0	0.8	0.2	-0.4	-0.9	-0.1	-1.2	0.2	0.2	-1.3	1.6
Lung FEV1/FVC ratio	0.2	1.0	3.1	-0.4	0.1	-1.2	-0.4	1.1	0.8	0.4	0.8	-1.4	-1.4	0.9	1.8
Lung FVC	0.6	2.9	8.4	-2.1	1.2	-2.9	-1.8	1.0	1.8	-1.4	1.4	-1.6	-0.7	2.4	-0.9
Neuroticism	0.5	1.1	4.3	-0.7	0.7	-2.1	-0.2	1.2	0.5	-1.6	0.7	-1.3	-0.2	0.9	0.9
Chronotype (morning person)	0.9	2.2	11.0	-1.4	2.1	3.3	-1.7	1.0	1.0	-1.4	0.6	0.5	-1.1	0.4	0.1
Hair Pigment	0.1	3.4	12.4	1.7	-1.8	-0.4	1.7	-2.6	-1.1	0.2	-1.4	1.6	2.0	-1.5	-3.5
Tanning	0.2	1.9	3.0	1.5	-0.9	0.9	1.6	-1.6	-1.4	1.6	-1.7	1.4	1.5	-1.1	-0.6
Hand grip strength (left)	0.1	0.3	1.0	-0.2	0.6	0.9	0.5	-0.5	0.0	-0.3	0.6	-0.6	-1.0	0.3	0.7
Number of treatments/medications taken	0.5	0.9	2.6	1.0	-1.6	-0.6	0.7	-0.6	-0.6	0.8	-0.6	0.8	1.2	-1.3	-0.6
Average weekly spirits intake	0.4	0.5	1.8	0.0	0.4	1.1	0.1	1.3	0.5	-0.1	-0.1	-0.7	-0.7	0.8	0.9
Sensitivity / hurt feelings	0.6	0.9	7.5	0.2	-1.0	-2.7	-0.1	0.0	-0.0	-0.4	0.5	-1.2	0.3	0.6	-0.7
Frequency of depressed mood in last 2 weeks	0.5	0.7	3.6	0.5	-0.2	1.4	0.5	-0.4	-0.5	0.1	-0.6	0.1	1.2	-1.9	0.2
Hearing difficulty/problems: Yes	0.2	0.3	1.2	0.6	0.3	1.1	0.5	0.7	-0.2	0.1	-0.5	0.4	0.5	-0.7	-0.1
Relative age of first facial hair	0.1	0.3	0.9	0.9	-0.8	-0.1	0.4	-0.6	-0.6	-0.1	-0.2	-0.8	-0.1	0.1	-0.3
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	4.2	0.4	-1.0	-1.0	0.4	-1.0	-0.2	-0.3	-0.3	-0.1	1.2	-0.3	-2.0
Ever used hormone-replacement therapy (HRT)	1.3	1.6	3.7	-1.3	1.5	0.8	-0.2	1.7	1.8	-0.5	1.9	-1.0	0.1	1.9	0.5
Ever had hysterectomy (womb removed)	0.4	0.5	1.9	-0.5	0.2	-1.1	-0.9	0.5	0.5	-1.4	0.2	0.8	-0.3	0.6	0.3
Systolic blood pressure, automated reading	0.6	1.8	14.4	-0.7	0.5	3.8	-0.3	0.3	0.8	0.3	1.7	-1.4	-0.5	0.3	-0.3
Eye problems/disorders: Diabetes related eye disease	1.8	2.0	3.8	-1.4	1.6	2.0	-1.7	0.9	1.4	-1.8	1.6	-0.9	-1.2	-0.2	1.7
Angina	0.4	0.6	1.1	-0.9	0.9	-0.6	-0.6	0.5	0.8	-1.1	0.8	-0.8	-0.0	0.9	0.7
Medication for hormone replacement therapy	0.3	0.3	1.1	-0.7	0.8	0.5	-0.4	0.2	1.1	0.5	0.6	0.3	0.7	-0.0	0.0
Vitamin and mineral supplements	0.2	0.3	1.6	0.1	0.1	1.3	-0.2	-0.2	-0.5	-0.4	0.2	0.4	0.5	0.4	0.9
Supplements: Zinc	0.8	0.8	4.0	1.1	-0.8	2.0	1.3	-0.6	-0.5	0.4	-0.7	0.5	0.2	-0.9	0.3
Medication: Co-codamol	0.5	0.6	3.7	0.1	-0.0	0.3	0.2	0.7	0.6	-0.2	0.5	-0.9	-0.2	0.9	1.9
Medication: Metformin	1.1	1.6	3.3	1.4	-0.9	1.0	0.5	-1.2	-1.6	-0.2	-1.7	1.8	-0.3	-1.4	1.8
Diabetes (father)	0.6	0.7	3.5	0.7	0.8	1.9	0.1	0.3	-0.6	1.3	-0.3	1.0	-0.1	-0.7	0.1
Diabetes (mother)	1.1	1.4	4.7	-1.3	1.3	-0.0	-1.0	0.6	1.1	-2.2	1.3	-1.2	-1.6	0.9	0.6
Severe depression (siblings)	0.5	0.5	1.7	-1.2	0.5	-1.3	-0.7	0.2	0.7	-0.4	0.9	-0.6	-0.3	0.2	0.7
Pack years adult smoking proportion	0.4	0.6	1.7	1.1	-0.4	0.1	-0.2	-1.3	-1.1	-0.3	-1.0	-0.0	-1.1	-0.6	0.8
Impedance of leg (right)	0.5	2.6	16.5	-0.8	-0.5	-4.1	0.1	-0.4	0.8	-1.0	0.8	-1.8	-1.2	1.6	-2.1
Leg fat-free mass (left)	0.6	3.4	14.4	1.0	0.6	3.8	0.2	-0.1	-0.8	0.5	-0.7	2.1	-0.9	-2.2	3.7
Trunk fat percentage	0.1	0.4	2.2	0.4	0.2	0.5	0.4	-0.4	-0.0	0.6	-0.3	0.4	-0.0	-1.5	1.2
Hand grip strength (right)	0.4	1.0	3.1	-0.0	0.4	1.8	0.9	-0.7	-0.0	0.2	0.8	-1.3	-1.6	0.3	1.4
Townsend deprivation index at recruitment	2.0	2.8	7.4	1.6	-1.1	0.3	1.1	-1.1	-1.8	1.6	-2.5	2.7	1.5	-1.7	-1.4
Current tobacco smoking	0.7	1.2	3.2	-0.1	1.0	-1.8	-0.5	0.8	1.0	0.4	0.6	-1.2	-1.5	1.7	0.9
Average weekly fortified wine intake	0.3	0.4	2.2	-0.2	0.0	1.5	-0.4	-0.3	0.3	-0.0	0.2	0.6	-0.9	-0.7	0.4
Maternal smoking around birth	1.9	2.8	9.1	1.3	-1.7	-0.7	1.2	-1.6	-0.8	3.0	-1.0	0.8	2.5	-1.3	-2.3
Fed-up feelings	0.4	0.7	3.3	-0.0	-0.5	-1.8	1.0	0.1	-0.2	-0.7	-0.1	-1.1	0.2	0.2	1.3
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.8	6.1	-1.1	1.1	-1.0	-1.2	1.2	1.3	-1.6	1.1	-2.5	-0.7	0.7	1.8
Relative age voice broke	0.2	0.4	1.2	0.1	-0.2	-0.3	0.5	0.2	-0.4	-1.1	0.4	-0.8	-0.3	0.7	1.0
Taking other prescription medications	1.8	2.8	4.8	2.2	-2.0	-1.5	1.4	-1.2	-1.8	1.1	-2.1	1.5	1.9	-2.0	-0.3
Age when periods started (menarche)	0.4	0.9	3.3	1.1	-0.9	-0.7	0.4	-0.6	-0.8	0.3	-1.3	1.8	0.7	-1.1	0.5
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	3.9	-1.3	1.0	-0.4	-2.0	1.3	1.4	-1.0	1.5	-0.5	-0.3	1.7	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.3	0.8	-0.6	-0.1	-0.1	-0.5	-0.9	0.6	0.2	0.1	-1.1	-0.2	0.3
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	3.8	1.2	-1.2	0.8	2.0	-1.2	-0.9	1.6	-0.7	-0.2	1.0	-1.2	-0.1
Qualifications: CSEs or equivalent	0.2	0.3	0.8	-0.4	0.3	0.8	0.1	-0.2	0.7	-0.2	0.6	-0.3	-0.3	-0.9	0.4
Serious illness, injury or assault to yourself	0.9	1.1	3.0	0.8	-1.4	-0.8	0.3	-1.5	-1.7	-0.0	-1.4	0.7	0.1	-0.7	-1.4
High blood pressure	0.3	0.8	5.0	0.5	-0.2	0.7	-1.1	0.2	-0.6	-0.3	0.2	0.2	-1.3	0.0	2.2
Hayfever, allergic rhinitis or eczema	0.1	0.3	0.8	-0.6	-0.3	-0.1	-0.9	-0.5	0.0	-0.3	0.5	-0.4	0.6	-0.3	-0.9
Multivitamins +/- minerals	0.7	0.9	4.7	0.2	-0.8	-1.1	1.0	-0.7	0.4	1.3	0.1	-1.0	0.3	0.1	-2.2
Stomach or abdominal pain in last month	0.9	1.2	4.8	-0.8	0.9	-0.4	-0.8	0.5	1.4	-0.6	1.5	-2.2	-1.1	0.4	0.8
Supplements: Glucosamine	0.3	0.4	1.2	0.4	-1.0	-0.3	0.0	-0.9	-0.5	-0.3	-0.9	0.5	0.3	-0.3	-1.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	3.5	0.7	0.4	-1.9	-0.7	0.1	-0.4	-0.7	-0.1	-0.6	-0.4	1.6	0.4
Medication: Atenolol	0.2	0.3	1.1	0.6	-0.1	0.4	0.5	0.7	-0.1	0.5	-0.1	-0.3	-0.2	-0.9	1.1
Medication: Levothyroxine sodium	0.4	0.8	4.1	0.8	-1.4	-2.0	-0.3	-0.8	-0.4	-0.6	-0.5	0.0	-0.2	-0.9	-0.1
Sitting height	0.5	3.4	12.3	-0.3	1.8	3.1	-0.4	1.4	0.7	0.6	0.9	1.3	-3.0	-0.1	3.5
Chronic bronchitis/emphysema (father)	0.2	0.3	1.1	-0.1	-0.3	0.4	0.2	-0.5	0.2	1.1	0.7	-0.4	0.3	-0.3	-0.7
High blood pressure (mother)	1.1	1.5	3.9	-1.3	0.1	0.4	-1.6	-0.2	0.8	-1.8	1.3	-2.0	-1.5	1.1	-0.7
Body mass index (BMI)	0.3	1.1	5.4	1.0	-0.0	1.8	0.5	-0.5	-0.4	0.3	-0.8	0.7	0.2	-1.5	2.3
Impedance of leg (left)	0.5	2.4	14.4	-0.9	-0.0	-3.8	-0.0	0.0	1.1	-0.8	1.1	-2.0	-1.3	1.3	-1.9
Leg predicted mass (left)	0.7	3.5	14.9	1.0	0.6	3.9	0.3	-0.1	-0.8	0.6	-0.7	2.1	-0.9	-2.2	3.8
Trunk fat mass	0.3	1.1	4.2	0.6	0.4	1.8	0.4	-0.4	-0.1	0.7	-0.3	0.8	-0.2	-1.9	2.1
Waist circumference	0.7	2.5	8.6	1.4	-0.4	2.9	0.7	-0.7	-1.1	0.6	-1.3	1.3	-0.1	-2.5	2.6
Number of incorrect matches in round	2.4	4.0	7.5	2.7	-1.7	-1.7	2.0	-2.2	-2.5	1.8	-2.5	1.7	0.0	-2.0	-1.7
Past tobacco smoking	0.5	0.9	3.5	0.2	-0.8	-1.9	0.1	-1.2	-0.2	0.7	-0.1	-1.4	-0.4	-0.9	-1.1
Alcohol usually taken with meals	0.4	0.6	1.6	-1.2	0.7	0.9	-0.7	0.7	0.3	-0.4	0.4	1.3	1.0	-0.3	0.5
Nervous feelings	0.3	0.5	4.4	0.1	0.4	-2.1	-0.3	0.1	0.1	0.2	0.4	-0.8	0.7	-0.0	-0.3
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	3.8	1.0	-0.4	-0.7	1.2	-0.5	-0.6	-0.0	-1.2	0.3	0.9	-1.9	0.3
Hearing difficulty/problems with background noise	0.8	1.3	6.9	1.0	-0.4	2.6	1.2	0.3	-0.5	0.6	-0.5	0.1	1.6	-0.8	-1.4
Hair/balding pattern: Pattern 2	0.4	0.5	2.3	0.7	-0.3	0.5	0.2	-0.5	-0.9	0.0	-0.2	0.4	-0.6	-1.2	1.5
Had menopause	0.8	1.0	5.4	-0.2	0.4	-0.6	0.8	1.6	0.6	-0.3	0.6	-0.7	0.8	2.3	-0.8
Had other major operations	0.1	0.1	0.4	-0.2	0.5	0.2	-0.4	-0.1	0.6	-0.1	0.5	-0.3	-0.0	-0.5	0.2
Forced vital capacity (FVC)	0.1	0.3	1.0	-0.1	0.1	0.5	-0.0	-0.7	-0.6	0.7	-0.1	0.7	-0.2	-1.0	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.8	1.1	-0.6	-0.1	0.3	-0.4	-1.3	0.9	-0.2	0.6	-0.6	-0.5	1.0
Ever unenthusiastic/disinterested for a whole week	1.7	2.0	8.5	1.4	-1.6	0.2	1.1	-1.1	-1.5	0.9	-1.6	1.2	1.5	-2.9	0.5
Qualifications: None of the above	0.7	1.6	4.0	-1.1	0.6	-2.0	-0.7	1.1	1.8	-1.3	0.8	-1.4	-1.0	1.7	-0.3
Financial difficulties in last 2 years	1.1	1.5	3.8	1.1	-1.3	-1.0	0.2	-1.4	-2.0	-0.5	-1.8	1.0	-0.5	-0.9	1.4
Mouth/teeth dental problems	0.4	0.6	3.5	0.2	0.1	1.9	0.7	0.4	-0.2	1.0	-0.2	0.5	0.9	0.6	-1.0
Heart attack	0.4	0.5	1.8	0.5	-0.7	-1.2	0.5	-0.9	-0.1	-0.3	-0.5	0.2	0.8	-0.1	-1.3
Allergy	0.5	1.2	2.7	-0.9	1.3	0.5	-0.6	1.4	1.3	-0.6	0.6	-0.3	-1.6	1.5	1.4
Pain all over the body in last month	0.4	0.5	1.2	0.8	-0.1	-0.9	-0.6	-0.1	-0.5	0.6	-1.1	0.8	-0.6	-0.4	0.9
Diabetes (self-reported)	0.7	1.0	3.5	1.0	-0.7	0.4	0.5	-0.7	-0.6	-0.5	-1.5	1.9	0.7	-1.7	0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.6	0.3	-0.8	-0.3	-0.1	0.3	-0.6	-0.3	-0.4	-0.0	0.4	0.0	-0.7
Medication: Ramipril	0.2	0.3	1.3	-0.0	-0.4	-0.1	-0.4	0.2	0.1	-0.3	0.2	1.2	0.9	0.5	-0.5
Medication: Simvastatin	0.2	0.3	0.9	0.3	-0.8	0.2	0.3	-0.9	-0.3	-0.2	0.2	-0.4	1.0	-0.9	-0.3
Fluid intelligence score	0.2	0.4	1.3	0.3	-1.1	-0.1	0.8	-0.9	-0.6	0.1	0.2	0.6	1.2	0.1	0.1
Illnesses of siblings	0.2	0.3	1.0	0.6	-0.2	-0.6	0.8	-0.4	-0.3	1.0	-0.5	0.7	0.4	0.3	-0.1
Neuroticism score	0.3	0.6	3.7	-0.3	0.6	-1.9	-0.1	0.9	0.0	-0.9	0.3	-0.9	0.1	0.0	0.8
Weight	0.6	2.7	12.9	0.8	0.6	3.3	0.2	-0.1	-0.3	0.5	-0.5	1.4	-0.7	-2.1	3.6
Impedance of arm (right)	0.5	2.4	12.6	-0.5	-1.1	-3.4	0.7	-0.8	-0.1	0.6	0.0	-0.3	1.2	-0.3	-3.5
Arm fat percentage (right)	0.2	0.8	3.6	0.7	-0.4	0.9	0.8	-1.0	-0.1	1.0	-0.6	0.4	1.1	-1.9	0.7
Trunk fat-free mass	0.7	3.8	21.4	0.8	0.8	4.6	0.1	-0.0	-0.1	0.4	-0.2	2.0	-1.2	-2.1	3.5
Hip circumference	0.5	2.2	7.1	1.4	-0.8	2.0	1.3	-1.1	-1.0	1.1	-1.3	1.8	0.5	-2.7	1.6
Time employed in main current job	1.2	1.4	3.0	-1.5	1.0	0.1	-1.5	1.1	1.4	-0.4	1.6	-1.4	-0.4	1.7	-0.1
Alcohol intake versus 10 years previously	0.3	0.5	2.2	1.5	-0.3	-0.1	0.6	-0.7	-0.9	0.6	-0.9	0.4	0.1	0.7	0.4
Father’s age at death	1.5	2.1	5.8	-1.9	0.9	0.2	-1.0	0.7	1.7	-2.0	1.9	-1.5	-0.3	2.4	-0.0
Worrier / anxious feelings	1.0	1.9	3.8	2.0	-1.6	-1.3	0.9	-1.4	-1.7	-0.0	-1.9	1.2	0.6	-1.8	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.7	0.3	-0.3	-1.3	-0.5	-0.7	0.1	-0.6	-0.6	-0.3	0.0	-1.2	0.5
Falls in the last year	0.6	0.8	2.4	-0.2	0.8	1.0	-0.2	0.7	1.6	0.5	0.9	-1.0	1.1	0.1	-1.3
Hair/balding pattern: Pattern 3	0.4	0.6	2.1	-1.0	-0.2	-1.5	-0.6	-0.0	0.4	-0.7	0.4	-0.0	0.6	0.5	-1.5
Number of live births	1.5	2.1	11.3	0.9	0.5	2.3	0.2	0.7	-1.2	-0.4	-0.9	1.8	-1.0	-0.8	3.4
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	0.9	-0.7	0.3	0.0	-0.5	-0.5	0.1	0.5	0.5	-0.2	-0.5	-0.4	1.0
Pulse rate	0.3	0.5	1.6	-0.5	0.5	-0.7	-1.3	0.1	0.7	-1.1	-0.9	0.6	-0.4	0.4	-0.2
Happiness	1.3	1.6	4.2	1.5	-1.5	-1.4	1.6	-2.1	-1.2	1.3	-1.3	0.2	0.1	-1.4	-0.1
Noisy workplace	0.8	1.0	2.8	-0.1	1.0	1.7	0.6	0.8	1.0	0.3	0.8	-1.7	-0.8	0.1	1.4
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.2	-0.9	1.1	1.0	-0.7	0.3	0.2	-0.1	0.8	-0.5	0.5	-0.8	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	1.9	-1.2	0.3	0.6	-1.4	-0.3	0.9	-0.4	1.0	-1.4	-1.0	0.4	-0.1
Mouth/teeth dental problems: Dentures	0.1	0.2	0.4	0.3	-0.1	-0.5	0.6	-0.5	0.6	-0.3	0.5	0.2	-0.0	-0.5	0.0
Asthma	0.8	1.5	3.1	1.8	-1.2	-0.7	1.0	-1.4	-1.6	1.2	-1.3	1.4	0.7	-1.1	-0.8
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.1	2.7	0.6	-1.6	-1.4	0.9	-1.1	-0.6	-0.2	-0.8	1.3	1.2	-1.1	-0.3
Medication: Cholesterol lowering	0.4	0.7	3.6	-0.3	0.4	1.9	-0.8	-0.4	0.1	-0.8	0.9	-0.5	-0.0	-0.1	1.3
Depression (self-reported)	0.2	0.2	1.1	0.3	-0.1	-0.2	0.1	0.0	-0.2	-0.2	-0.4	0.9	1.0	0.4	-0.1
Medication: Lansoprazole	0.4	0.5	1.6	0.6	-0.2	-0.6	0.5	-0.3	-0.9	-0.7	-1.0	1.3	0.5	-0.3	-0.8
Prospective memory result	2.1	2.5	5.6	-1.8	1.7	-0.4	-1.5	1.3	1.8	-1.1	1.7	-2.1	-1.7	2.4	0.7
Lung cancer (father)	0.3	0.3	1.5	-0.1	0.1	0.1	-0.1	0.1	0.8	-0.7	1.0	0.1	-0.7	1.2	0.1
Illnesses of mother	0.9	1.1	4.1	1.3	-0.8	0.4	1.8	-0.4	-0.4	2.0	-0.8	0.7	1.2	-0.7	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	1.1	-0.5	-0.4	0.2	-0.6	-1.1	-0.6	0.6	0.4	-0.3	0.3	-0.4	0.4
Pulse wave Arterial Stiffness index	4.9	5.8	9.7	-2.8	2.4	1.1	-2.3	2.5	3.0	-2.2	2.5	-1.9	-3.1	2.9	0.9
Impedance of arm (left)	0.4	2.0	11.2	-0.4	-0.8	-3.4	0.3	-0.7	-0.3	0.5	-0.2	-0.4	0.6	0.3	-3.3
Arm fat mass (right)	0.4	1.5	4.8	1.0	-0.0	2.0	0.7	-0.7	-0.3	0.8	-0.9	1.1	0.3	-2.2	2.0
Trunk predicted mass	0.7	3.8	21.6	0.8	0.8	4.7	0.0	-0.1	-0.1	0.3	-0.2	2.0	-1.3	-2.1	3.5
Standing height	0.3	3.1	14.3	-0.1	1.4	3.8	-0.4	0.8	0.2	0.3	0.6	1.4	-2.5	-1.4	3.1
Length of working week for main job	0.3	0.3	0.8	-0.7	0.7	0.0	-0.3	0.1	0.5	-0.5	0.9	-0.1	-0.9	0.2	0.9
Exposure to tobacco smoke at home	0.4	0.4	1.9	0.1	0.2	-0.1	0.2	-0.0	0.2	0.3	-0.4	1.4	0.4	-1.2	0.9
Breastfed as a baby	0.7	0.9	3.4	-0.3	0.5	0.4	0.8	1.0	0.7	-0.3	1.4	-0.5	0.3	1.8	-1.3
Tense / ‘highly strung’	0.1	0.1	0.4	0.1	0.3	-0.6	-0.1	0.4	-0.4	-0.0	-0.2	0.3	0.4	-0.6	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	1.8	0.1	-0.7	-0.1	0.7	-0.9	-0.3	-0.4	-0.0	0.4	1.3	-0.2	-1.3
Hair/balding pattern: Pattern 4	0.2	0.5	2.2	-0.2	0.7	-1.5	0.4	1.2	1.0	0.5	0.0	0.4	0.5	0.4	0.1
Birth weight of first child	0.2	0.3	1.5	0.1	-0.2	0.3	-0.4	-0.2	-0.4	-0.3	-0.7	1.2	0.0	0.3	-1.2
Peak expiratory flow (PEF)	0.5	1.2	4.0	-1.5	0.4	2.0	-1.3	-0.2	0.8	-0.3	1.3	-1.4	-1.0	0.7	0.9
Pulse wave reflection index	0.8	0.9	2.2	-1.4	1.0	0.3	-1.1	1.1	0.8	-0.4	1.1	-0.6	-0.9	1.5	-0.3
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.7	-0.5	1.3	0.5	-0.4	0.7	1.1	-0.6	1.1	-0.8	-0.9	0.5	0.3
Loud music exposure frequency	0.3	0.3	2.0	0.4	-0.7	-1.4	-0.2	-0.3	0.4	-0.3	-0.1	-0.3	0.5	-0.1	-0.1
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	4.2	-0.7	1.1	1.8	-0.7	0.3	0.3	-0.7	1.2	-1.2	-1.4	0.0	2.1
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	4.0	-0.8	0.1	-2.0	-0.9	-0.1	0.1	-0.8	-0.1	0.5	0.5	-0.9	-0.0
Blood clot in the leg (DVT)	1.9	2.4	6.8	1.5	-1.1	0.9	2.6	-1.7	-1.2	1.6	-0.6	0.2	2.1	-2.0	-1.4
Medication: Paracetamol	0.5	0.9	4.6	0.2	-0.5	-2.1	0.9	0.7	-0.2	1.1	-0.5	0.5	1.3	-0.9	-0.5
Headache pain in last month	1.0	1.7	3.8	0.9	-1.9	-1.1	1.3	-1.5	-1.0	1.0	-0.4	-1.7	1.3	-0.1	-1.8
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	3.0	-1.2	0.8	-1.7	-0.2	1.4	1.1	-0.0	0.6	-0.2	-0.2	0.9	-0.3
Glaucoma (self-reported)	1.6	1.9	7.2	-0.6	1.0	2.3	-0.7	0.6	0.6	-1.7	0.9	0.2	-2.7	0.7	1.9
Gout (self-reported)	0.7	1.0	2.4	-1.0	0.9	0.1	-1.4	1.2	0.8	-0.3	1.5	-0.8	0.9	0.1	1.3
Hypothyroidism/myxoedema (self-reported)	0.1	0.3	1.6	0.2	-0.3	-1.3	-0.3	0.2	0.5	-0.6	-0.2	0.3	0.2	-0.7	-0.2
Medication: Amlodipine	0.4	0.6	2.4	0.8	-0.0	0.5	0.3	-0.3	-0.9	1.0	-0.8	1.6	0.2	-1.1	0.5
Medication: Ventolin 100micrograms inhaler	0.4	0.6	4.3	0.5	-0.7	-2.1	0.4	-0.4	0.5	0.5	-0.0	-0.6	0.2	-0.1	-0.7
Birth weight	0.3	0.7	2.4	-0.7	0.2	0.7	-0.1	0.8	1.0	0.2	1.1	-1.5	-0.3	1.3	-0.4
Chronic bronchitis/emphysema (mother)	1.2	1.4	7.4	0.4	-0.5	1.4	0.7	-1.4	-1.2	1.0	-1.1	0.8	0.5	-2.7	-0.4
High blood pressure (siblings)	0.1	0.2	0.7	-0.1	-0.5	-0.7	-0.7	-0.2	-0.2	-0.2	-0.1	-0.4	-0.4	-0.1	-0.9
Forced vital capacity (FVC), Best measure	0.1	0.4	1.6	-0.2	-0.5	0.7	-0.5	-1.2	-1.0	0.5	-0.0	0.5	0.2	-0.7	-0.2
Body fat percentage	0.1	0.3	1.8	0.2	0.3	0.5	0.2	-0.3	0.3	0.5	-0.1	0.1	-0.0	-1.2	1.3
Leg fat percentage (right)	0.1	0.3	1.8	-0.0	0.1	0.4	0.2	-0.2	0.8	-0.2	0.4	-0.5	-0.2	-0.5	1.3
Arm fat-free mass (right)	0.8	3.9	19.2	1.0	1.1	3.8	-0.1	0.3	-0.5	0.3	-0.6	2.0	-1.9	-1.6	4.4
Exposure to tobacco smoke outside home	0.4	0.6	3.4	-0.4	0.4	0.5	-0.0	0.4	0.6	0.0	-0.1	1.9	0.8	-1.2	0.2
Comparative body size at age 10	0.1	0.3	1.6	0.1	-0.9	0.2	-0.2	0.3	0.1	-0.4	0.4	-0.1	-0.1	1.3	0.5
Number of full brothers	0.2	0.3	0.8	-0.6	0.5	-0.4	-0.9	0.2	0.7	0.0	0.4	0.8	0.3	-0.3	0.6
Worry too long after embarrassment	0.8	1.3	4.3	0.7	-1.1	-0.6	1.3	-0.0	-0.5	1.3	-0.7	0.8	2.1	-1.8	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.1	-0.7	0.2	-0.7	-0.8	-0.5	0.4	-0.5	1.1	-0.7	-0.3	0.6	-0.6
Wheeze or whistling in the chest in last year	2.3	4.1	7.8	2.6	-2.6	-2.8	1.2	-1.9	-1.8	2.2	-2.1	1.4	1.9	-1.8	-0.9
Number of children fathered	0.8	0.9	3.0	-1.1	1.1	1.1	-0.7	1.7	1.0	0.0	1.0	0.6	0.9	-0.1	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	2.0	-0.4	-0.6	-0.8	-0.1	-0.2	-0.4	0.6	-0.2	0.7	1.3	-1.4	-0.6
Age at first live birth	0.3	0.6	2.9	-0.4	-0.6	-0.3	-1.2	-0.8	0.3	-1.7	-0.2	-0.8	-0.4	-0.3	0.3
Pulse wave peak to peak time	4.3	5.0	8.3	2.7	-2.1	-0.6	2.2	-2.3	-2.9	2.2	-2.2	1.9	2.8	-2.9	-0.6
Health satisfaction	0.3	0.4	2.3	0.2	-0.1	-0.5	-0.7	-0.8	0.2	-1.5	0.2	-0.3	0.4	-0.5	1.0
Shortness of breath walking on level ground	0.5	0.7	2.9	-0.6	0.4	-1.7	-0.8	0.4	1.1	-1.2	0.2	-0.2	0.9	-0.2	-0.2
Qualifications: College or University degree	0.3	0.8	2.7	0.3	-0.8	-0.7	0.4	-1.0	-1.2	1.1	-0.3	0.3	1.7	-0.6	-1.0
Eye problems/disorders: None of the above	1.3	1.5	3.4	-1.6	0.2	-1.6	-1.1	0.5	1.2	-0.5	0.8	-0.9	1.6	1.8	-1.6
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.3	0.5	0.4	-0.3	-0.3	-0.2	-0.0	-0.3	-0.1	0.3	-1.1	-0.4	0.2
Emphysema/chronic bronchitis	0.5	0.6	1.9	-0.1	0.0	0.2	-0.2	-0.0	-0.7	-0.9	-0.1	1.0	0.7	-1.4	1.4
Medication for pain relief, constipation, heartburn	0.5	0.9	3.0	-0.3	1.3	1.7	-0.7	0.5	0.6	-0.5	0.6	-0.8	-1.3	1.2	0.8
Neck or shoulder pain in last month	0.6	0.9	2.4	-1.0	0.8	0.6	-1.4	0.2	1.3	-0.9	1.6	-0.8	-0.2	0.8	0.9
Medication: Blood pressure	0.3	0.6	1.6	1.1	-0.9	1.0	-0.4	-1.3	-1.2	-0.2	-0.7	-0.1	-0.6	-0.6	0.4
Angina (self-reported)	0.4	0.5	1.0	-0.8	0.5	-0.8	-0.5	0.2	0.6	-1.0	0.6	-1.0	0.1	0.9	0.3
Migraine (self-reported)	0.8	1.0	3.8	0.8	0.6	1.1	1.3	1.6	0.3	1.9	0.0	-0.7	-0.1	0.4	-0.6
Medication: Ibuprofen	1.3	1.6	3.5	1.1	-1.9	-1.4	1.3	-1.6	-0.9	0.7	-0.9	1.2	1.4	-1.3	-1.1
Medication: Allopurinol	0.8	1.1	2.2	-1.5	1.0	0.7	-1.5	1.4	1.0	-0.8	1.4	-0.7	0.6	0.7	0.7
Medication: Omeprazole	0.1	0.1	0.4	-0.6	0.4	-0.3	-0.1	0.2	-0.3	0.5	-0.4	0.1	0.1	-0.2	-0.3
Medication: Seretide 50 evohaler	0.4	0.4	0.9	1.0	-0.7	-0.1	0.9	0.2	-0.5	0.9	-0.9	0.4	-0.0	-0.8	0.0
Mean time to correctly identify matches	0.3	0.5	1.6	-0.7	0.7	-0.6	-0.5	0.9	1.2	0.4	1.0	-0.5	-0.1	-0.0	-0.8
Heart disease (mother)	0.9	1.1	3.6	0.1	-0.0	-1.9	-0.3	0.6	0.3	-0.0	1.0	-1.3	-1.4	1.5	1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.8	0.5	0.4	1.3	0.9	-0.4	0.2	0.3	-0.2	-0.1	0.5	-0.2	-0.4
Whole body fat mass	0.3	1.2	4.9	0.7	0.3	1.9	0.2	-0.4	-0.1	0.8	-0.5	0.8	-0.4	-1.9	2.2
Leg fat mass (right)	0.2	0.9	5.9	0.6	0.1	1.4	0.3	-0.3	0.2	0.0	-0.2	0.5	-0.7	-1.3	2.4
Arm predicted mass (right)	0.7	3.7	17.5	1.2	0.9	3.7	-0.1	0.2	-0.6	0.5	-0.6	2.0	-1.8	-1.7	4.2
Pulse rate, automated reading	0.5	1.5	5.1	1.1	-1.3	-1.0	0.2	-2.3	-1.2	-0.4	-1.8	1.2	-0.8	-1.4	0.1
Alcohol intake frequency.	0.7	1.7	3.2	1.8	-1.6	-0.3	1.7	-1.4	-1.1	0.9	-1.5	0.8	1.2	-1.8	-0.0
Comparative height size at age 10	0.8	4.3	12.1	1.7	-0.6	3.5	0.6	-0.8	-2.3	1.8	-1.5	3.0	-0.4	-3.3	2.0
Number of full sisters	0.5	0.6	2.3	0.3	-0.2	1.5	1.2	-0.2	-0.5	0.8	-0.5	0.8	0.6	-0.7	-0.5
Suffer from ‘nerves’	1.8	2.9	8.2	-2.1	2.0	-0.5	-1.6	2.9	1.3	-1.7	1.3	-1.7	-0.6	2.3	0.8
Overall health rating	0.3	0.7	2.2	1.3	-0.7	-0.6	0.2	-1.5	-0.6	0.0	-0.9	0.1	0.9	-1.3	-0.1
Chest pain or discomfort	1.2	1.7	3.1	1.1	-1.6	-1.4	1.3	-1.6	-0.9	0.7	-1.4	0.2	1.3	-1.8	-1.5
Had major operations	0.3	0.4	2.3	0.1	-0.1	0.2	-0.3	0.6	-0.3	-0.1	0.2	-0.7	-1.0	0.4	1.5
Age at last live birth	0.3	0.5	2.2	0.4	-0.2	0.1	0.1	-0.9	-0.0	-1.1	-0.6	-0.5	-0.0	-1.5	0.6
Family relationship satisfaction	0.1	0.1	0.4	-0.1	0.3	-0.3	0.5	0.3	0.1	-0.0	0.3	-0.7	-0.4	0.4	-0.0
Leg pain on walking	1.0	1.2	3.7	-0.6	0.6	-1.1	-1.9	0.8	0.6	-1.9	0.1	0.7	-1.3	-0.7	1.5
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	2.0	1.2	-1.0	0.8	1.4	-0.9	-0.8	-1.0	-0.4	-0.3	-0.4	-0.8	1.4
Commuting to job workplace: Car/motor vehicle	0.5	0.5	3.1	-0.1	0.2	-1.1	-0.2	-0.5	0.8	0.3	0.9	-1.8	0.1	0.2	-0.4
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	3.9	-0.0	0.5	2.0	0.5	1.0	0.6	0.8	0.5	0.3	1.1	0.3	1.0
Medication: Aspirin	0.3	0.5	1.6	0.5	-0.9	0.0	0.6	-0.8	-0.3	-0.1	-0.7	0.2	1.0	-1.3	0.5
Supplements: Vitamin C	0.4	0.4	1.9	0.2	0.3	-0.9	-0.5	0.6	0.2	-0.6	-0.2	0.6	-1.4	-0.1	1.0
Knee pain experienced in last month	1.0	1.6	4.2	-1.9	1.4	-0.8	-0.7	1.3	2.1	-1.2	2.0	-1.0	0.0	0.1	-0.4
Hypertension (Self-reported)	0.3	0.8	6.4	0.5	-0.1	0.6	-1.2	0.2	-0.6	0.0	0.1	0.4	-1.1	0.1	2.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	2.7	1.3	-0.5	1.1	0.8	-0.9	-1.5	1.0	-1.2	0.0	0.1	-1.4	-1.6
Illnesses of father: Heart disease	0.6	0.9	2.6	-1.0	0.3	-1.0	-1.6	0.1	0.8	-0.0	1.1	-1.2	-0.1	-0.5	1.4
Illnesses of siblings: Diabetes	0.9	1.2	4.4	-1.3	1.3	1.4	-0.6	0.7	0.5	-2.1	1.0	-0.2	-0.8	-0.3	1.1
Smoking status: Previous	0.6	0.9	3.4	-0.3	0.7	1.8	-0.2	1.2	0.5	-0.9	0.2	0.8	-0.2	1.3	1.3
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.2	3.1	1.1	-0.4	1.2	1.7	-1.0	-0.9	1.8	-0.5	1.1	0.5	-1.3	0.2
Whole body fat-free mass	0.7	4.0	19.8	0.9	0.9	4.5	0.1	0.1	-0.4	0.5	-0.5	2.0	-1.3	-2.2	4.0
Leg fat-free mass (right)	0.7	3.6	15.9	0.8	0.9	4.0	0.0	0.2	-0.5	0.7	-0.4	2.0	-0.9	-2.2	3.8
Arm fat percentage (left)	0.2	0.8	3.0	0.9	-0.5	0.7	0.6	-1.1	-0.5	1.0	-0.8	0.5	0.8	-1.7	0.7
Average weekly red wine intake	0.3	0.4	1.5	-0.5	0.8	0.2	-1.0	0.5	-0.2	0.4	-0.1	1.0	-0.0	0.2	1.2
Handedness (chirality/laterality): Left-handed	1.3	1.6	3.8	1.1	-1.8	0.0	1.1	-0.9	-1.0	0.7	-1.9	1.3	1.3	-1.9	-0.1
Mood swings	0.4	0.7	1.7	1.1	-0.9	-1.3	0.8	-1.2	-0.9	-0.3	-0.9	-0.2	-0.0	-0.9	0.7
Loneliness, isolation	0.3	0.4	1.4	-0.3	0.2	-0.1	1.0	0.6	-0.1	-0.6	0.5	-1.1	1.2	0.0	-0.4
Long-standing illness, disability or infirmity	1.3	2.0	6.0	1.0	-1.7	-2.5	0.1	-1.5	-1.0	0.8	-1.5	1.1	0.8	-2.2	-0.9
Ever had bowel cancer screening	1.0	1.2	4.2	-0.3	0.5	1.9	0.4	0.5	0.3	-0.4	0.2	2.0	1.8	0.2	-1.3
Diabetes diagnosed by doctor	0.7	1.1	3.9	0.5	0.1	1.1	-0.3	-0.1	-0.4	-1.3	-1.1	1.6	-0.1	-1.5	2.0
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	3.8	-0.9	1.2	0.3	-0.9	0.9	0.4	-0.8	0.2	0.6	-1.9	-0.5	1.0
Friendships satisfaction	0.3	0.4	1.8	0.6	-0.7	-0.2	0.7	-0.5	-0.6	1.3	-0.1	0.0	0.6	-0.7	0.0
Qualifications: nursing, teaching	0.3	0.4	1.2	0.1	0.1	0.8	0.8	-0.7	0.0	0.9	0.3	-0.5	1.0	-1.1	-0.5
Commuting to job workplace: Walk	0.8	0.8	1.7	0.7	0.1	1.2	0.5	-0.1	-0.6	-0.7	-1.3	1.2	-1.2	-0.9	1.2
Eye problems/disorders: Cataract	2.2	2.6	6.2	2.1	-0.8	1.7	1.2	-1.1	-2.2	1.1	-2.1	1.6	-0.4	-2.5	1.0
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.4	-0.6	-0.4	0.1	-0.8	0.3	0.5	-0.2	0.2	-1.2	-0.6	-0.3	0.8
Medication for cholesterol	0.4	0.6	1.4	1.1	-0.4	0.7	0.8	-0.5	-1.2	0.7	-1.0	0.5	0.1	-1.0	0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	3.1	-1.1	0.3	0.2	-1.4	0.1	1.3	-1.2	1.2	-1.3	-1.8	1.4	-0.1
Back pain experienced in last month	1.8	2.6	8.0	-1.8	1.3	0.9	-2.4	0.7	1.3	-2.8	1.5	-0.8	-1.7	0.2	1.9
Mineral and other dietary supplements	0.2	0.2	1.2	0.1	0.4	0.3	0.6	-0.0	0.0	0.5	1.1	-0.5	0.1	0.6	0.5
Breast cancer (self-reported)	0.3	0.3	1.0	0.3	-0.9	-0.9	0.4	-0.3	-0.3	-0.1	-0.1	-0.1	0.1	0.9	-1.0
Asthma (self-reported)	0.8	1.6	3.1	1.8	-1.3	-0.9	0.9	-1.5	-1.7	1.3	-1.4	1.4	0.6	-1.1	-1.0
Osteoporosis (self-reported)	0.4	0.5	2.5	0.2	-1.1	0.4	0.3	-0.4	-0.5	-0.5	-0.4	-0.6	0.4	1.6	-0.7
Osteoarthritis (self-reported)	1.8	2.3	6.3	-1.4	1.3	-0.8	-2.2	2.5	1.8	-1.2	1.5	-0.9	-0.9	1.3	1.4
Medication: Aspirin	0.7	0.9	2.7	0.8	-1.1	0.3	0.7	-0.8	-0.8	-0.0	-1.1	1.0	1.3	-1.6	0.5
Medication: Gliclazide	1.0	1.1	6.2	-0.7	1.0	2.5	-0.4	0.7	1.1	-0.4	1.0	-0.3	-0.6	0.5	1.4
Illnesses of father: None of the above (group 1)	0.2	0.3	1.0	-0.2	-0.0	0.2	-0.1	0.5	0.3	-1.0	-0.3	0.5	0.4	0.9	-0.9
Smoking status: Current	0.8	1.2	3.7	-0.3	1.1	-1.9	-0.7	0.8	1.1	0.1	0.7	-1.2	-1.5	1.7	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.5	-0.3	-0.6	-1.3	0.0	-1.4	0.4	0.4	0.7	-1.3	1.0	0.7	-1.6
Whole body water mass	0.7	4.1	20.0	0.9	0.9	4.5	0.1	0.1	-0.4	0.4	-0.5	2.1	-1.2	-2.2	4.0
Leg predicted mass (right)	0.7	3.5	15.5	0.8	0.9	3.9	0.0	0.2	-0.5	0.7	-0.5	2.0	-0.9	-2.2	3.8
Arm fat mass (left)	0.4	1.4	4.2	1.1	-0.2	2.1	0.6	-1.0	-0.6	0.8	-0.9	1.0	0.2	-2.0	1.9
Number of self-reported non-cancer illnesses	0.7	1.2	2.9	1.4	-1.7	-1.4	-0.1	-1.2	-1.1	0.4	-1.2	-0.0	0.9	-1.1	-1.3
Average weekly champagne plus white wine intake	0.3	0.4	1.0	0.1	-0.8	0.7	1.0	-0.5	0.4	-0.8	0.4	-0.0	1.0	-0.0	0.4
Miserableness	0.3	0.5	1.3	-0.7	-0.1	-1.0	0.0	0.2	-0.2	-0.9	0.2	-0.8	1.1	-0.2	1.1
Guilty feelings	0.2	0.3	1.0	0.2	0.1	-0.3	0.5	0.5	-0.3	-0.1	-0.1	-0.8	0.8	-0.7	1.0
Wears glasses or contact lenses	0.4	0.4	2.2	0.1	0.2	1.2	0.1	0.3	0.5	-1.5	-0.2	0.3	0.3	-0.2	0.8
Ever taken oral contraceptive pill	0.4	0.4	2.7	-0.1	-0.2	1.6	0.5	-0.5	0.2	-0.2	0.7	0.3	0.1	-0.0	0.9
Hearing aid user	3.5	4.0	7.3	-2.2	2.4	-1.1	-2.7	2.7	1.6	-2.3	1.5	-0.3	-1.7	1.3	2.7
Mother’s age at death	1.4	1.7	4.4	-1.4	1.9	1.3	-1.1	1.5	0.5	-2.1	0.4	0.1	-1.0	0.6	2.1
Financial situation satisfaction	1.8	2.2	8.4	1.7	-1.6	0.7	1.2	-1.4	-1.8	1.3	-1.8	0.5	0.5	-2.9	-0.5
Tinnitus: Yes, now most or all of the time	0.4	0.4	2.2	0.0	0.2	-1.5	-0.8	0.0	-0.1	-0.9	0.2	0.1	-0.3	0.8	-0.8
Commuting to job workplace: Public transport	0.9	1.1	2.4	0.2	-0.7	-0.4	0.4	-0.6	-1.3	1.5	-1.4	1.0	1.4	-1.6	-1.1
Eye problems/disorders: Glaucoma	1.5	1.7	10.3	-0.0	1.1	1.7	-0.1	0.9	0.1	-1.1	0.5	0.5	-3.2	-0.0	1.9
Medication: Blood pressure	0.1	0.3	2.2	0.3	-0.2	-0.3	-0.1	-0.0	0.2	-0.1	0.3	-0.1	-0.7	0.3	1.5
Pain type(s) experienced in last month: Hip pain	0.4	0.5	2.4	-0.6	-0.2	-1.5	-0.6	-0.1	0.6	-0.9	0.3	-0.2	1.2	0.2	0.0
Supplements: Fish oil (including cod liver oil)	0.6	0.7	2.5	0.4	-0.1	1.0	-1.0	0.4	-0.2	0.1	-1.4	1.6	-0.2	-1.1	0.8
High cholesterol (Self-reported)	0.0	0.1	0.6	0.2	-0.1	-0.0	-0.3	-0.3	-0.1	-0.3	0.1	-0.2	0.8	-0.1	-0.3
Medication: Bendroflumethiazide	0.4	0.6	1.3	1.1	-0.5	-0.7	-0.9	-0.3	-1.1	0.4	-1.1	1.0	-0.3	-0.6	0.8
Medication: Paracetamol	0.3	0.5	1.5	0.2	-0.5	-1.2	0.6	0.6	-0.6	0.7	-0.4	0.3	1.0	-0.8	-0.4
Medication: Lisinopril	0.8	1.0	3.4	1.8	-1.2	-0.3	0.5	-1.4	-1.3	-0.2	-1.5	0.4	-0.8	-0.5	-0.1
Medication: Atorvastatin	1.6	2.0	5.4	-1.2	1.4	-0.9	-1.4	0.5	1.5	-2.3	1.2	-1.1	-1.7	1.8	0.9
Illnesses of father: High blood pressure	0.6	0.7	3.1	0.8	-0.9	-0.6	0.4	-1.2	-1.8	0.2	-0.5	-0.6	-0.7	-0.5	0.4
Alcohol drinker status: Never	0.4	0.5	1.6	1.0	-0.2	1.3	1.1	-0.6	-0.4	0.4	-0.6	0.1	-0.9	-0.6	-0.0
Ever smoked	0.5	0.9	3.2	0.4	0.5	1.5	0.0	1.1	-0.4	0.2	-0.5	1.8	1.1	0.0	1.3
Basal metabolic rate	0.7	3.9	18.2	0.9	0.8	4.3	0.2	-0.0	-0.5	0.6	-0.5	2.0	-1.0	-2.4	3.9
Leg fat percentage (left)	0.1	0.5	2.1	-0.4	0.5	0.5	-0.1	0.1	1.2	-0.1	0.8	-0.8	-0.2	-0.6	1.4
Arm fat-free mass (left)	0.7	3.5	18.4	0.4	1.3	3.8	-0.3	0.5	0.1	0.0	0.1	1.6	-1.4	-1.5	4.3
Number of operations (self-reported)	0.8	1.2	5.8	0.1	0.6	1.1	-0.6	0.6	-0.1	-1.0	0.2	-1.2	-2.4	-0.1	2.0
Average weekly beer plus cider intake	0.6	0.9	2.2	-0.4	1.0	-0.2	-0.5	0.3	1.0	-0.4	1.2	-1.2	-1.3	0.8	1.5
Irritability	0.6	1.0	3.0	-0.4	1.6	-1.6	-1.5	0.7	0.1	-0.7	0.1	-0.7	-0.7	-0.5	1.7
Risk taking	0.4	0.6	3.5	-1.0	0.6	0.9	-1.9	-0.2	0.3	0.1	-0.1	1.0	0.4	-0.8	-0.4
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.5	0.6	0.1	1.5	-0.5	-0.4	-0.3	0.7	-0.7	1.6	0.6	-1.2	0.3
Fractured/broken bones in last 5 years	0.5	0.7	2.5	0.2	0.6	1.6	0.1	0.5	-1.0	-0.9	-0.6	0.3	-1.6	0.4	-0.1
Age started oral contraceptive pill	0.2	0.2	0.9	0.4	-0.1	-0.6	0.6	-0.1	-0.0	0.2	0.2	0.7	0.9	0.2	-0.5
Diastolic blood pressure, automated reading	1.1	3.4	7.4	2.1	-2.2	0.4	1.7	-2.7	-2.0	2.0	-1.7	1.5	0.1	-2.7	-0.7
Ever depressed for a whole week	0.9	1.1	2.5	1.1	-1.4	-0.5	0.4	-1.1	-1.5	0.9	-1.1	0.8	1.6	-0.9	-0.1
Unable to work because of sickness or disability	0.4	0.5	2.7	0.2	0.1	-0.1	-0.6	-0.4	0.1	-1.6	-0.1	-1.1	-1.1	-0.6	0.4
Commuting to job workplace: Cycle	1.1	1.3	4.3	1.0	-1.4	0.3	2.1	-1.0	-1.0	0.3	-1.4	1.2	0.5	-0.7	-1.3
Myopia	0.6	0.9	3.7	-0.9	0.0	1.9	-0.5	-0.4	0.3	0.3	-0.4	0.5	1.4	-0.9	-1.5
Vascular/heart problems diagnosed by doctor	0.2	0.4	1.5	-0.9	0.8	-0.7	0.5	0.4	0.9	-0.1	0.3	-0.3	0.4	0.4	-1.2
Cholesterol lowering medication	0.4	0.6	2.0	-0.2	-0.4	-1.2	0.4	-0.7	0.2	-0.7	0.3	-0.5	1.3	0.2	-1.4
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	1.6	-1.2	1.3	-0.7	-1.1	1.1	0.5	-0.3	0.1	-0.6	-0.6	0.9	0.5
Pain experienced in last month	0.7	1.2	2.7	0.6	-0.6	1.5	0.5	-0.1	-1.2	1.2	-1.5	1.6	-0.1	-0.8	-1.4
Supplements: Calcium	1.1	1.2	4.2	-1.3	0.2	-0.8	-0.8	1.2	1.1	-0.3	0.7	-0.9	0.8	2.1	-1.6
Basal cell carcinoma (self-reported)	0.8	0.9	3.5	1.1	-0.9	1.9	0.6	-1.2	-0.8	0.6	-0.7	0.7	-0.9	-1.1	-0.0
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.6	0.3	-0.5	-1.2	0.2	-0.8	0.1	-0.5	-0.2	-0.1	0.6	0.3	-1.3
Deep venous thrombosis (DVT) (self-reported)	2.4	3.1	7.6	1.8	-1.6	0.7	2.8	-2.1	-1.5	1.6	-0.9	0.5	2.6	-2.2	-1.5
Heart disease (siblings)	1.3	1.6	4.5	-1.2	1.6	0.2	-2.1	1.3	1.0	-1.6	1.2	-1.2	-0.3	0.6	1.3
Alcohol drinker status: Previous	0.6	0.7	2.9	0.1	0.3	1.0	-0.1	-0.1	-0.1	-0.6	-0.2	0.4	-0.9	-1.7	1.7
Pack years of smoking	0.3	0.5	1.6	0.8	-0.2	0.1	-0.2	-1.1	-0.8	-0.3	-0.6	-0.3	-1.3	-0.5	0.8
Impedance of whole body	0.5	2.4	16.1	-0.6	-0.5	-4.0	0.3	-0.5	0.2	-0.2	0.4	-1.3	-0.5	0.9	-2.9
Leg fat mass (left)	0.2	1.0	6.4	0.4	0.3	1.5	0.1	-0.2	0.4	0.1	0.0	0.2	-0.8	-1.4	2.5
Arm predicted mass (left)	0.7	3.8	18.3	0.9	1.1	4.0	0.1	0.1	-0.2	0.2	-0.3	1.8	-1.4	-1.9	4.3