Hub : Genes

RAB38

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Artery Tibial 0.0816 0.0360 9.8e-03 0.019 NA 0.000 NA 0.005 1.1e-02 NA 3.5e-01 NA 1.1e-01
2 GTEx Cells Transformed fibroblasts 0.1460 0.0670 1.0e-02 0.068 NA 0.040 NA 0.060 7.7e-06 NA 5.2e-04 NA 2.6e-05
3 GTEx Esophagus Mucosa 0.1830 0.0540 2.8e-04 0.081 NA 0.110 NA 0.129 4.3e-06 NA 8.1e-08 NA 6.0e-09
4 GTEx Esophagus Muscularis 0.1460 0.0480 6.1e-04 0.056 NA 0.023 NA 0.061 2.5e-04 NA 1.4e-02 NA 1.4e-04
5 GTEx Liver 0.4710 0.0890 3.9e-06 0.333 NA 0.219 NA 0.274 4.6e-10 NA 9.4e-07 NA 2.6e-08
6 GTEx Lung 0.1448 0.0493 3.9e-04 0.098 NA 0.081 NA 0.077 6.1e-08 NA 9.0e-07 NA 1.6e-06
7 GTEx Nerve Tibial 0.1782 0.0602 4.2e-04 0.040 NA 0.091 NA 0.078 7.8e-04 NA 5.7e-07 NA 3.7e-06
8 GTEx Pancreas 0.3100 0.0780 9.7e-05 0.154 NA 0.217 NA 0.165 5.0e-07 NA 1.4e-09 NA 1.9e-07
9 GTEx Skin Not Sun Exposed Suprapubic 0.2980 0.0630 5.3e-07 0.090 NA 0.141 NA 0.149 1.3e-05 NA 3.8e-08 NA 1.6e-08
10 GTEx Skin Sun Exposed Lower leg 0.1840 0.0450 1.5e-07 0.157 NA 0.150 NA 0.168 5.6e-13 NA 1.9e-12 NA 7.2e-14
11 METSIM Adipose 0.1662 0.0338 1.9e-12 0.094 0.104 0.097 0.107 0.109 5.6e-14 3.1e-15 2.8e-14 1.2e-15 5.1e-16
12 NTR Blood 0.0242 0.0095 2.0e-03 0.002 0.010 0.011 0.013 0.009 6.0e-02 3.3e-04 1.1e-04 3.3e-05 3.8e-04
13 YFS Blood 0.3256 0.0386 0.0e+00 0.111 0.192 0.214 0.200 0.188 3.0e-34 9.2e-61 4.2e-68 1.7e-63 3.5e-59
14 TCGA Bladder Urothelial Carcinoma 0.0880 0.0350 2.3e-05 0.052 0.040 0.039 NA 0.045 3.5e-05 2.6e-04 2.6e-04 NA 9.6e-05
15 TCGA Colon Adenocarcinoma 0.1090 0.0460 7.3e-04 0.029 0.014 0.020 NA 0.038 7.8e-03 4.6e-02 2.5e-02 NA 3.0e-03
16 TCGA Glioblastoma Multiforme 0.2600 0.0950 1.5e-04 0.095 0.183 0.151 NA 0.111 8.0e-04 3.1e-06 2.5e-05 NA 3.1e-04
17 TCGA Head and Neck Squamous Cell Carcinoma 0.0736 0.0358 5.0e-04 0.004 0.024 0.010 NA 0.004 1.0e-01 1.0e-03 2.5e-02 NA 1.1e-01
18 TCGA Brain Lower Grade Glioma 0.0712 0.0244 1.2e-07 0.101 0.072 0.086 NA 0.094 1.7e-11 1.4e-08 5.8e-10 NA 9.2e-11
19 TCGA Lung Squamous Cell Carcinoma 0.0413 0.0233 5.9e-03 0.015 0.007 0.002 NA 0.018 7.5e-03 4.7e-02 2.0e-01 NA 3.7e-03
20 TCGA Ovarian Serous Cystadenocarcinoma 0.1120 0.0500 2.0e-03 -0.003 0.033 0.000 NA 0.000 6.5e-01 2.8e-03 3.3e-01 NA 3.0e-01
21 TCGA Pancreatic Adenocarcinoma 0.1580 0.0720 4.3e-03 0.081 0.041 0.005 NA 0.055 2.8e-04 8.2e-03 2.0e-01 NA 2.5e-03
22 TCGA Prostate Adenocarcinoma 0.1655 0.0505 1.2e-10 0.071 0.095 0.082 NA 0.072 6.9e-08 3.8e-10 6.5e-09 NA 5.1e-08
23 TCGA Soft Tissue Sarcoma 0.0840 0.0430 7.1e-03 -0.004 0.007 -0.003 NA -0.004 6.2e-01 1.2e-01 5.0e-01 NA 8.1e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bipolar Disorder (2018) 4.5 7.1 14.2 3.4 1.8 2.4 2.4 1.9 3.8 1.6 0.0 2.5 3.5 3.6 2.4 2.4 3.5 3.0 3.7 3.3 3.1 1.5 -1.1 1.7 2.1 2.7
Bipolar Disorder or Schizophrenia 1.1 2.6 5.3 2.3 1.5 0.9 1.7 1.6 2.3 1.3 0.3 1.0 2.1 2.3 1.3 1.2 2.2 2.2 1.5 1.3 2.3 -0.1 -0.6 1.2 1.2 2.0
Depressed Affect (Nagel 2018) 0.8 1.8 9.1 -0.7 -0.2 -1.3 -0.3 -0.1 -0.5 -0.6 1.6 -2.1 -1.2 -1.1 -2.6 -1.7 -1.2 -0.9 -0.6 -1.2 -1.0 -3.0 -0.8 0.1 -1.8 -0.7
Depression (Nagel 2018) 0.4 0.7 3.2 -0.2 0.4 -1.1 0.3 0.1 0.1 -0.0 0.1 -1.6 -0.1 -0.3 -1.3 -1.0 -0.6 0.1 0.1 -1.4 0.0 -1.8 -0.2 0.1 -1.7 0.0
Intelligence (Savage-Jansen 2018) 0.6 1.9 3.3 1.4 1.4 1.1 1.6 1.3 1.5 1.0 -1.7 1.4 1.4 1.5 1.7 1.5 1.8 1.6 1.7 0.6 1.8 1.4 0.1 1.0 -0.3 0.9
Neuroticism (Nagel 2018) 1.5 3.6 8.1 -2.0 -1.5 -1.6 -1.7 -1.0 -1.8 -1.9 1.2 -2.2 -1.9 -2.3 -2.5 -2.8 -2.3 -1.8 -1.0 -1.7 -1.9 -2.8 -0.1 -0.9 -2.4 -1.5
Schizophrenia (2018) 0.1 0.3 1.4 0.2 0.4 -0.8 0.3 0.6 -0.1 0.3 0.3 -0.7 -0.1 0.0 -0.2 -0.4 -0.0 0.4 -1.0 -1.0 0.5 -1.2 0.1 0.3 -0.2 0.3
Schizophrenia vs Biploar Disorder 3.2 4.2 12.0 -1.9 -0.5 -3.2 -1.2 -0.5 -2.3 -0.8 -0.4 -2.6 -2.9 -1.7 -2.9 -1.9 -2.5 -1.5 -3.4 -3.5 -1.4 -2.0 1.1 -0.7 -1.5 -1.9
Worry (Nagel 2018) 0.8 1.8 7.3 -1.4 -1.2 -0.9 -1.3 -0.8 -1.5 -1.8 0.7 -0.9 -1.2 -1.7 -2.1 -2.7 -1.4 -1.0 -1.2 -1.6 -1.2 -1.1 -0.2 -0.8 -0.9 -0.8
Alzheimer’s Disease (in mother) 0.3 0.3 1.8 -0.1 0.3 -0.8 0.4 0.5 0.5 0.9 -0.1 -0.8 -0.4 0.5 0.5 0.8 -0.5 -0.2 -0.3 0.5 -0.1 -0.1 -0.7 0.5 1.4 -0.5
Alzheimer’s Disease (in father) 0.7 0.8 3.4 0.3 0.8 1.8 1.0 0.6 -0.0 -0.3 0.4 1.8 1.6 0.4 -0.1 -0.0 1.2 0.4 -0.6 0.5 0.6 1.3 -0.5 0.5 0.9 1.0
Alzheimer’s Disease (including proxy) 0.4 0.6 1.7 0.6 1.1 0.6 1.3 1.1 0.8 -0.1 0.7 0.6 1.1 0.2 0.4 1.2 0.8 -0.0 -0.1 0.7 0.2 0.8 -0.7 1.2 1.3 -0.2
Crohns Disease (2017) 0.3 0.6 6.4 -0.7 0.2 0.8 0.1 0.1 -0.2 -0.8 -0.3 0.9 1.1 -0.6 -1.1 -0.9 -0.0 -0.5 0.6 0.2 -0.4 2.5 0.4 0.0 -0.4 -0.8
Irritable Bowel Disease (IBD) 0.3 0.8 7.7 -0.5 -0.1 1.2 -0.2 -0.2 -0.9 -1.1 -0.3 1.1 1.4 -0.5 -1.0 -0.8 0.2 -0.3 0.2 0.1 -0.2 2.8 0.6 -0.4 -0.7 -0.6
Ulcerative Colitis (UC) 0.3 0.5 4.4 0.1 0.0 0.8 -0.0 0.3 -1.1 -0.8 -0.6 1.0 1.2 0.3 -0.9 -0.4 0.7 0.4 -0.3 -0.1 0.5 2.1 0.3 0.1 -0.0 0.2
Major Depression (MDD) 0.3 0.4 1.7 -0.3 -0.8 0.3 -0.8 -0.7 -0.2 0.7 -1.0 -0.0 -0.3 0.1 -0.7 -1.3 -0.6 -0.3 -0.2 -0.2 -0.4 0.3 -0.4 -0.9 -0.5 -0.1
Reaction Time 0.8 1.4 5.3 0.4 0.9 1.6 1.1 1.5 1.3 -0.3 0.5 1.5 2.3 0.6 -1.5 -1.0 1.2 0.7 0.7 1.2 0.8 1.8 1.1 0.7 1.4 0.8
Verbal and Numeric Reasoning (VNR) 0.9 2.1 5.5 1.3 2.0 1.3 2.3 1.7 1.3 0.7 0.1 1.5 1.5 1.4 0.8 1.8 2.0 1.7 1.4 1.6 1.8 1.0 -0.4 1.5 0.4 0.9
Breast Cancer 0.5 1.2 4.4 1.4 1.5 0.0 1.4 0.8 0.5 0.7 -1.6 -0.5 0.1 0.8 2.1 1.6 0.5 0.8 1.1 -0.1 0.9 -2.0 -0.1 0.7 -1.0 0.8
Ovarian Cancer 0.2 0.3 1.4 0.3 -0.1 0.3 -0.1 -0.3 -0.6 -0.5 0.0 0.4 0.4 0.5 0.1 0.9 0.6 0.5 -0.0 0.9 0.5 -0.0 0.3 -0.1 1.2 0.6
Prostate Cancer 1.2 1.7 5.8 1.3 1.0 1.5 1.3 1.5 0.8 0.9 -1.1 1.4 1.2 1.5 1.3 1.7 1.5 1.0 1.9 2.4 1.1 0.3 0.1 1.1 1.1 1.2
Age at First Birth 1.0 1.5 4.3 1.4 0.9 1.6 0.9 0.0 0.5 -0.9 0.6 1.7 1.6 0.7 0.2 1.2 1.8 1.0 1.2 2.0 1.2 0.7 -1.3 0.1 2.1 1.2
Bipolar Disorder (2011) 0.9 0.9 4.7 0.7 -0.8 0.3 -0.4 -0.7 1.1 -0.3 0.5 -0.2 0.9 1.6 0.8 0.1 1.0 1.1 2.2 1.8 1.1 0.2 -0.4 -0.9 0.3 0.8
Body Mass Index (BMI) (2010) 2.3 3.2 5.4 -2.3 -2.0 -1.5 -2.1 -1.5 -1.6 -1.5 1.5 -2.1 -1.8 -2.2 -2.2 -2.3 -2.2 -1.6 -1.9 -1.8 -1.8 -2.1 -0.5 -1.5 -0.9 -0.5
Coronary Artery Disease (CAD) 0.2 0.2 1.0 -0.0 -0.3 0.1 -0.0 0.5 -0.1 -0.7 0.5 0.2 0.8 0.0 0.8 0.3 1.0 0.8 0.2 0.3 1.0 -0.0 -0.1 0.2 0.3 0.3
Crohns Disease (2012) 0.5 0.8 4.6 0.5 1.0 1.2 1.0 0.7 1.2 -0.3 -0.0 0.9 1.6 -0.0 0.2 0.7 0.8 0.3 1.3 0.5 0.5 2.2 -0.4 0.7 -0.1 -0.2
Mean Putamen Volume 0.7 0.8 3.3 1.1 0.6 0.0 0.8 0.7 1.8 1.0 -0.2 0.0 0.7 1.5 0.2 0.9 0.7 1.0 0.5 0.9 0.9 0.0 -1.1 1.0 0.9 0.7
Fasting Glucose 2.3 2.7 9.8 -1.7 -2.3 -0.8 -2.2 -3.1 -2.2 -1.6 -0.2 -0.5 -1.3 -1.5 -2.2 -2.5 -1.1 -1.1 -1.3 -1.1 -1.2 -0.2 0.1 -2.7 -0.8 -1.0
HbA1C 0.9 1.0 2.4 0.0 1.2 -0.0 1.1 1.5 0.4 1.0 0.8 0.8 0.1 1.6 -0.9 -0.8 1.1 1.2 -1.0 -0.3 1.2 0.4 -0.9 1.5 1.4 0.9
HDL Cholesterol 2.8 4.6 10.3 2.3 1.8 2.0 2.1 1.5 2.4 1.2 -1.2 2.0 2.7 2.3 2.2 3.2 2.5 2.1 2.2 3.2 2.3 1.8 -0.6 1.3 2.8 1.4
LDL Cholesterol 0.3 0.5 2.0 -0.6 0.3 1.4 0.3 0.3 -0.9 -0.5 0.8 1.4 1.0 -0.6 0.1 -0.2 0.5 -0.3 -0.8 0.1 -0.2 0.2 -0.8 0.1 1.1 1.4
Lupus 0.2 0.2 1.7 0.1 0.1 -0.3 -0.0 0.2 -0.3 0.0 -0.6 -0.3 0.0 -0.4 0.6 0.1 -0.2 0.1 0.5 -0.2 0.1 0.9 1.3 0.1 -0.3 -1.2
Neuroticism (2016) 2.6 3.8 10.9 -2.7 -1.8 -0.1 -1.9 -1.3 -2.0 -2.6 0.5 0.1 -0.9 -2.2 -2.5 -1.8 -1.4 -2.8 -3.3 -2.2 -2.5 0.8 1.1 -1.7 -1.6 -2.2
Primary Biliary Cirrhosis 0.3 0.5 3.7 -1.0 -0.4 -0.4 -0.3 0.1 -0.4 0.3 1.0 -0.5 -0.1 -0.3 -0.8 -1.9 -0.9 -0.8 -0.3 0.4 -0.9 0.8 -0.2 0.2 0.3 -0.1
Rheumatoid Arthritis 0.2 0.2 1.0 0.8 0.1 0.5 0.3 -0.1 0.9 0.2 -0.3 -0.1 0.6 0.0 0.2 0.4 0.4 0.4 0.7 0.3 0.4 -0.1 1.0 -0.3 -0.5 0.2
Schizophrenia (2014) 0.3 0.6 1.8 0.8 1.2 -0.7 1.1 1.3 0.9 1.2 0.4 -0.3 0.5 0.9 0.4 0.5 0.6 1.0 0.1 -0.4 1.2 -0.4 -0.2 1.1 0.4 0.9
Triglycerides 0.7 1.2 3.5 -1.4 -1.1 -1.5 -1.3 -1.1 -0.5 0.3 1.1 -1.0 -1.0 -1.1 -0.1 -1.1 -1.6 -1.0 -1.2 -1.9 -1.3 -0.2 -1.3 -1.0 -0.5 -0.0
Type 2 Diabetes (T2D) (2012) 2.4 2.8 19.5 -1.4 -1.8 0.3 -1.7 -1.3 -1.1 -1.8 0.1 -0.3 0.1 -0.8 -4.4 -4.2 -0.2 -0.5 -1.7 -0.6 -0.5 -1.7 1.1 -1.7 -0.6 -0.1
Ulcerative Colitis 0.8 1.1 2.9 -1.3 -1.1 1.1 -1.2 -1.1 -1.1 -1.6 0.3 0.7 0.5 -1.1 -1.7 -0.8 -0.4 -1.2 -0.8 -0.3 -1.0 1.6 0.5 -1.3 -1.0 -0.9
Blood Eosinophil Count 0.5 4.0 12.2 -2.3 -1.8 -0.4 -1.7 -1.8 -3.0 -1.6 -1.5 -1.0 -1.7 -1.8 -2.5 -2.4 -2.0 -2.6 -1.8 0.8 -2.4 -1.8 3.5 -1.9 -1.0 -1.7
Blood Platelet Count 0.1 1.0 3.1 0.1 -1.1 1.3 -0.9 -1.5 0.8 1.8 0.6 1.0 0.9 0.0 1.6 0.7 -0.3 -0.9 0.6 0.0 -1.1 1.5 -0.6 -1.6 -0.4 0.1
Blood Red Count 0.2 1.7 6.5 -1.9 -1.2 0.7 -1.2 -1.1 -0.8 -2.5 0.2 -0.2 0.3 -1.9 -2.0 -1.8 -0.7 -1.4 0.5 1.6 -1.3 0.1 1.8 -1.1 -0.5 -1.0
Blood White Count 0.2 1.3 5.4 -1.0 -1.9 -1.1 -1.8 -1.7 -0.5 0.4 2.3 -1.2 -0.9 -0.7 0.5 -0.9 -1.4 -0.9 1.1 0.4 -1.2 0.1 -0.8 -1.6 -0.1 -0.5
Heel T-Score 0.2 1.4 5.0 0.8 1.1 -1.6 0.8 1.2 0.6 1.1 -1.5 -1.9 -0.5 1.3 -1.2 -1.2 -0.1 0.8 2.2 -0.2 0.9 -1.1 0.4 1.1 -1.4 -1.2
BMI 1.1 6.3 16.0 -3.3 -1.9 -3.0 -2.4 -1.4 -1.7 -1.5 1.0 -3.4 -3.3 -2.9 -4.0 -2.3 -3.7 -2.5 -1.6 -1.9 -2.8 -2.6 1.1 -1.4 -1.7 -2.9
Height 0.0 0.7 5.5 0.4 0.4 -0.2 0.2 0.9 0.4 0.2 -1.1 0.8 -0.2 0.1 0.9 -0.6 -0.0 0.2 -1.4 -1.9 0.1 2.3 0.4 0.3 0.2 -0.2
Waist Hip Ratio (WHR) 1.1 4.8 14.7 -2.2 -2.6 -1.9 -2.6 -2.4 -1.6 -1.3 -0.8 -1.5 -2.5 -2.4 -0.2 -0.4 -2.6 -2.0 -2.7 -3.8 -2.1 0.5 1.7 -2.5 -3.3 -2.4
Systolic Blood Pressure 0.1 0.7 1.7 -1.0 -0.6 -1.3 -0.9 -0.5 -1.1 -0.3 1.1 -1.1 -1.1 -0.9 -1.3 -0.9 -1.0 -0.6 -0.7 0.0 -0.6 -0.8 -0.5 -0.4 0.6 -0.2
Smoking Status 0.5 1.2 3.6 -1.2 -1.7 -0.7 -1.8 -1.8 -0.8 0.5 1.5 -1.2 -0.9 -0.6 0.2 -0.5 -1.4 -1.1 0.5 0.3 -1.3 0.3 -0.1 -1.9 -0.6 -0.3
Allergy or Eczema 0.2 0.4 2.2 -0.5 -0.3 1.1 -0.1 -0.4 -0.5 -0.6 -0.1 0.7 0.4 0.5 -1.0 -0.6 0.4 -0.5 -0.5 1.5 -0.3 -1.2 0.3 -0.4 0.8 0.6
Cardiovascular Disease 0.2 0.7 1.8 -0.5 -0.7 -0.2 -0.9 -0.9 0.1 1.1 0.4 -0.5 -1.1 -0.4 -1.2 -1.4 -0.9 -1.0 -0.7 -0.8 -1.2 -0.2 -0.5 -1.0 -1.1 0.2
Hypothyroidism (self reported) 0.5 1.2 4.9 -0.1 -0.5 -1.3 -0.2 0.1 -0.4 0.3 0.4 -1.2 -0.8 -0.3 -2.1 -2.2 -0.8 0.0 -1.6 -1.9 -0.2 -1.6 0.5 0.1 -1.5 0.6
Respiratory disease 0.5 1.0 2.9 1.0 0.4 0.5 0.7 0.6 1.4 1.5 -0.6 0.6 1.1 1.2 1.7 0.3 1.1 1.2 1.0 1.4 1.1 0.9 -1.1 0.4 1.2 0.8
Type 2 Diabetes (T2D) (2018) 1.0 1.9 3.8 -1.7 -1.2 -0.8 -1.3 -1.1 -1.5 -1.4 1.7 -1.2 -1.6 -2.0 -1.5 -1.3 -1.7 -1.7 -1.7 -1.1 -1.8 -1.3 -0.9 -1.1 -0.2 -0.8
Lung FEV1/FVC ratio 0.3 1.7 9.2 -0.8 -0.6 -1.4 -0.7 -0.9 -0.6 -1.0 -0.7 -2.2 -1.4 -0.6 -0.3 0.0 -1.1 -0.3 0.1 -1.3 -0.2 -3.0 1.6 -0.7 -2.8 -1.5
Lung FVC 0.2 1.3 4.5 -0.9 -1.0 1.7 -0.9 -1.0 -1.3 -1.3 0.8 1.1 0.2 -1.4 1.1 0.1 -0.1 -1.5 -1.5 -0.9 -1.3 0.6 0.3 -1.2 -2.1 -0.2
Neuroticism 0.9 2.1 9.8 -1.5 -0.8 -0.7 -0.9 -0.3 -2.0 -1.6 1.7 -1.2 -0.6 -1.5 -3.1 -3.1 -1.2 -1.4 -1.2 -0.5 -1.4 -1.7 -0.5 -0.5 -0.5 -0.7
Chronotype (morning person) 0.3 0.8 4.0 0.2 0.3 0.6 0.5 0.2 2.0 0.6 0.9 0.6 0.2 1.0 1.1 1.9 0.6 0.4 0.9 1.3 0.5 1.1 -0.1 0.4 0.7 -0.2
Hair Pigment 0.1 2.2 12.7 -0.4 -0.3 -2.8 -0.3 -2.2 -0.9 0.1 0.4 -3.6 -1.8 -0.5 1.0 0.4 -1.7 0.3 0.7 -1.5 -0.0 -2.9 0.6 -1.4 -1.3 1.0
Tanning 0.7 8.3 39.6 3.4 2.5 1.7 2.2 3.4 2.7 2.5 -3.0 1.9 3.4 2.7 6.3 4.7 3.0 2.5 1.9 0.7 2.8 0.5 -2.3 3.3 2.1 -0.5
Hand grip strength (left) 0.4 1.0 4.6 0.9 0.8 2.1 0.9 0.8 0.2 0.5 -1.2 1.7 1.5 0.6 1.5 0.7 1.3 0.4 0.8 0.8 0.5 0.7 0.9 0.3 -0.4 1.0
Number of treatments/medications taken 0.3 0.6 5.7 0.3 -0.2 0.6 -0.2 -0.4 -0.3 -0.4 1.3 -0.3 -0.2 -0.6 -1.0 -0.9 0.2 -0.3 -0.2 0.4 -0.4 -2.4 -0.4 -0.5 -1.1 0.9
Average weekly spirits intake 0.5 0.6 2.7 0.4 0.6 -0.5 0.7 0.5 0.5 0.8 0.7 -0.3 0.1 1.4 -0.2 0.8 0.6 0.8 1.7 1.3 0.9 0.1 -0.5 0.7 0.8 -0.3
Sensitivity / hurt feelings 0.3 0.6 4.2 -1.3 -0.1 -0.6 -0.3 -0.1 -0.5 -0.0 2.0 -0.8 -0.3 -0.4 -0.5 -0.4 -0.9 -0.7 0.5 0.4 -0.7 -0.9 -1.2 0.1 -0.5 -0.8
Frequency of depressed mood in last 2 weeks 0.2 0.3 1.1 0.2 0.7 -0.2 0.8 0.9 0.7 0.7 0.4 -0.5 0.4 0.2 -0.7 -0.1 0.2 0.2 -0.0 -0.6 0.3 -1.0 -0.5 0.6 -0.4 0.5
Hearing difficulty/problems: Yes 0.7 1.0 5.0 1.6 -0.4 -0.6 0.0 -0.7 1.3 0.2 -0.0 -0.9 0.1 1.0 1.1 0.5 0.6 1.5 1.2 0.2 1.3 -2.2 -0.7 -0.8 -0.2 1.7
Relative age of first facial hair 0.9 1.8 7.9 1.0 1.2 0.4 1.2 0.7 0.2 1.1 1.4 0.8 0.9 1.2 1.1 1.0 1.2 1.3 1.4 2.4 1.1 0.0 -1.4 1.0 2.8 2.4
Other serious medical condition/disability diagnosed by doctor 0.6 0.7 2.2 1.0 0.0 1.4 0.5 -0.3 0.2 0.1 0.9 1.2 1.1 0.4 0.1 0.4 1.3 1.0 0.6 1.1 0.8 0.4 -0.9 0.1 1.3 1.5
Ever used hormone-replacement therapy (HRT) 1.2 1.5 7.9 -0.9 0.4 -2.4 0.1 -0.0 -0.6 -0.2 1.0 -2.7 -1.4 -0.6 -2.3 -0.6 -1.0 0.3 0.3 -0.8 0.2 -2.8 -0.1 0.4 -1.3 -0.8
Ever had hysterectomy (womb removed) 1.1 1.3 3.8 -0.7 -0.0 -1.7 -0.3 -0.1 -0.3 -0.0 1.4 -1.8 -1.6 -1.1 -1.0 -0.6 -1.4 -0.6 -1.7 -1.9 -0.7 -2.0 -0.6 0.1 -1.3 -0.5
Systolic blood pressure, automated reading 1.0 3.0 8.2 -2.4 -0.8 -2.6 -1.3 -0.8 -1.8 -0.8 1.6 -2.9 -2.6 -1.9 -2.0 -1.7 -2.6 -1.5 -1.4 -0.7 -1.6 -2.0 -0.2 -0.6 -0.7 -1.0
Eye problems/disorders: Diabetes related eye disease 0.5 0.5 3.7 -0.4 -0.5 -0.8 -0.6 -0.5 -0.2 -1.2 0.6 -1.0 -0.8 -0.7 -0.8 0.1 -0.4 -0.0 -0.9 -1.2 -0.0 -1.9 -0.4 -0.4 -0.2 -0.0
Angina 0.3 0.4 2.0 0.1 0.6 -0.8 0.2 0.8 0.4 0.7 -0.4 -0.7 -0.9 -0.1 -0.8 -1.4 -0.7 -0.3 0.0 -0.2 -0.4 -0.6 -0.5 0.8 -0.4 -0.1
Medication for hormone replacement therapy 0.4 0.4 2.6 0.2 0.5 -0.6 0.7 0.8 0.4 -0.6 -0.2 -0.6 -0.2 0.3 -1.5 0.4 -0.0 0.5 0.3 0.3 0.6 -1.6 0.9 0.9 -0.1 -0.1
Vitamin and mineral supplements 1.1 1.4 4.3 1.1 1.2 0.2 1.2 1.3 1.4 2.0 0.3 0.2 0.8 1.4 1.9 1.3 1.1 1.2 2.1 1.1 1.0 -0.0 -1.0 1.2 0.8 0.9
Supplements: Zinc 1.3 1.4 5.4 -1.0 -0.9 -0.1 -1.0 -1.0 -1.0 -1.0 -2.3 0.1 -0.3 -1.0 -0.2 -0.3 -1.2 -1.8 -1.6 -1.1 -1.4 0.7 1.5 -1.4 -1.6 -1.5
Medication: Co-codamol 1.2 1.4 5.6 -0.7 -1.2 -2.4 -1.3 -0.7 -0.8 0.2 1.0 -1.9 -1.8 -0.1 -1.3 -1.8 -1.4 -0.2 -1.8 -1.7 -0.3 -0.8 -0.8 -0.6 -0.3 0.1
Medication: Metformin 0.5 0.7 2.5 -0.4 0.1 -1.0 -0.2 -0.3 -0.6 0.1 1.2 -1.1 -1.2 -1.1 0.0 -0.8 -1.1 -0.7 -0.6 -1.6 -0.9 -1.0 -0.3 -0.2 -1.3 -0.8
Diabetes (father) 0.8 1.0 3.1 -0.8 -1.0 0.0 -1.0 -1.2 -0.7 -0.3 -1.5 -0.2 -0.6 -0.8 -0.4 -0.7 -0.9 -0.9 -1.5 -1.8 -1.0 0.5 1.6 -1.1 -1.6 -0.6
Diabetes (mother) 0.3 0.4 2.7 -1.2 -0.5 0.3 -0.2 -0.3 -0.5 -0.5 -0.1 -0.1 0.2 0.1 0.6 -0.0 -0.2 -0.1 0.8 0.8 0.0 0.5 1.6 -0.2 -0.9 -0.6
Severe depression (siblings) 1.9 2.1 4.6 -1.2 -2.1 -0.6 -2.1 -1.9 -1.7 -1.3 -0.0 -1.1 -1.1 -1.7 -0.9 -1.5 -1.4 -1.4 -1.8 -1.8 -1.5 -1.1 0.2 -2.1 -1.7 -0.1
Pack years adult smoking proportion 0.6 0.9 3.6 -0.5 -1.4 0.1 -1.1 -1.4 -0.7 -0.5 1.9 -0.3 -0.5 -1.1 -0.2 -1.7 -0.7 -0.9 0.5 0.7 -1.1 -1.1 -0.5 -1.2 -0.2 -0.2
Impedance of leg (right) 0.2 0.8 3.0 1.2 -1.1 1.3 -0.8 -1.5 -0.2 0.3 -0.5 1.4 1.3 0.0 1.7 1.0 0.9 0.1 -0.1 -0.1 0.1 0.9 -0.5 -1.3 0.1 0.0
Leg fat-free mass (left) 0.3 1.4 5.0 -2.0 0.1 -1.0 -0.3 0.3 -0.6 -0.7 0.2 -1.2 -1.4 -1.2 -2.2 -1.3 -1.7 -1.2 -1.3 -1.3 -1.3 -0.1 1.4 0.1 -0.9 -1.5
Trunk fat percentage 1.2 4.6 10.8 -3.2 -1.8 -1.4 -2.2 -1.7 -1.9 -1.6 0.8 -2.0 -2.6 -2.5 -2.7 -1.1 -3.0 -2.9 -1.7 -1.0 -3.0 -1.1 1.6 -1.6 -1.7 -3.3
Hand grip strength (right) 0.9 2.4 8.0 1.7 1.3 2.8 1.7 1.3 1.1 0.2 -1.1 2.3 2.7 1.5 1.4 0.5 2.4 1.3 1.5 1.4 1.5 0.8 0.6 0.8 -0.1 1.7
Townsend deprivation index at recruitment 0.6 0.8 2.8 -0.4 -0.6 -0.2 -0.8 -0.9 0.4 1.3 1.7 -0.3 -0.8 -1.2 0.4 0.6 -1.2 -1.5 -0.1 0.1 -1.6 1.0 0.0 -0.6 -0.5 -1.0
Current tobacco smoking 0.4 0.7 5.3 -0.7 -0.8 -1.2 -0.6 -0.6 0.2 1.2 2.3 -1.1 -0.5 0.3 1.1 0.3 -0.9 -0.2 1.0 0.6 -0.3 0.0 -0.3 -0.5 -0.0 -0.1
Average weekly fortified wine intake 1.2 1.5 5.3 1.4 0.2 2.3 0.6 0.2 0.4 -1.3 -0.4 2.0 2.2 0.1 1.2 1.3 1.7 0.5 1.2 2.2 0.7 0.4 0.6 0.1 0.6 0.8
Maternal smoking around birth 0.4 0.6 2.2 -0.3 -0.7 0.6 -0.6 -1.1 -1.0 -0.2 1.3 -0.1 0.2 -0.2 -0.1 -1.1 -0.1 -0.4 1.3 1.5 -0.6 -0.3 0.5 -1.2 -0.2 -0.3
Fed-up feelings 0.1 0.2 0.6 -0.2 0.6 0.0 0.6 0.0 -0.2 0.6 0.5 -0.3 0.3 -0.0 -0.8 -0.3 -0.3 -0.4 0.1 0.2 -0.4 -0.8 -0.2 0.2 -0.5 -0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.7 0.9 4.0 -0.6 0.5 -1.3 0.3 0.5 -0.1 0.2 1.4 -1.8 -0.3 -0.3 -2.0 -1.7 -0.8 -0.0 -0.1 -0.6 -0.1 -1.5 -1.0 0.6 -0.5 0.5
Relative age voice broke 0.4 0.5 4.2 0.1 0.3 0.9 0.5 0.1 0.2 0.6 -0.5 0.8 1.3 0.9 2.0 1.1 0.4 0.0 -0.0 0.5 0.1 0.9 0.0 0.1 0.2 0.6
Taking other prescription medications 0.3 0.4 1.8 -0.1 -0.7 1.3 -0.4 -1.0 -0.4 0.0 0.6 1.0 0.4 -0.5 -0.3 -0.6 0.0 -0.9 -0.6 0.2 -0.9 0.2 0.5 -0.8 -0.3 0.3
Age when periods started (menarche) 0.3 0.6 3.1 0.2 -1.2 0.6 -1.1 -1.8 -0.3 0.0 0.8 0.8 0.1 -0.7 0.9 -0.1 -0.1 -0.3 -0.5 -0.8 -0.5 1.3 -0.2 -1.4 -0.4 0.7
Bilateral oophorectomy (both ovaries removed) 0.6 0.7 4.2 0.0 0.1 -1.1 0.0 0.1 -0.7 0.3 1.3 -0.9 -1.1 -0.7 -1.5 -2.0 -0.7 -0.2 -0.4 -0.0 -0.4 -1.7 -0.4 0.4 0.5 0.5
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.5 3.8 -0.7 0.3 -0.7 0.4 0.5 -0.4 1.0 -0.4 -1.4 -0.6 0.8 -2.0 -0.6 -0.4 -0.0 0.7 0.6 0.0 -0.4 0.5 0.6 -0.3 -0.0
Tinnitus: Yes, but not now, but have in the past 1.2 1.2 5.5 -0.6 -1.5 0.9 -1.3 -1.2 -0.9 -1.7 -1.5 0.3 0.1 -0.8 0.1 -0.3 -0.5 -1.2 -0.3 -0.2 -1.2 -0.7 2.3 -1.8 -1.4 -0.5
Qualifications: CSEs or equivalent 1.2 1.5 3.9 -1.5 -1.6 -1.2 -1.6 -1.6 -0.9 -0.3 -0.7 -1.4 -1.4 -1.2 -0.1 -0.4 -2.0 -1.4 0.1 -1.0 -1.6 0.3 1.5 -1.4 -1.6 -1.1
Serious illness, injury or assault to yourself 0.5 0.7 4.2 0.6 0.6 -0.8 0.6 0.6 0.7 1.2 1.1 0.0 -0.1 0.6 -1.0 -0.4 0.0 0.6 -0.8 -0.4 0.4 0.3 -2.0 0.8 1.3 0.3
High blood pressure 0.1 0.4 2.1 -0.2 0.2 -0.5 -0.1 0.1 1.1 1.4 0.6 -0.7 -0.8 0.4 -0.1 -1.1 -0.4 -0.2 -0.1 -0.2 -0.4 0.2 -0.9 0.0 -0.3 0.5
Hayfever, allergic rhinitis or eczema 0.2 0.3 1.4 -0.3 -0.7 1.0 -0.3 -0.6 -0.7 -0.2 0.1 0.9 0.5 0.4 -1.2 -0.2 0.3 -0.6 -1.0 0.6 -0.4 -0.1 0.1 -0.5 0.4 -0.1
Multivitamins +/- minerals 2.4 3.1 5.9 -1.8 -1.9 -0.7 -1.9 -2.0 -2.1 -2.3 -1.1 -0.9 -1.2 -1.9 -1.5 -1.5 -1.7 -1.7 -2.4 -1.6 -1.5 -0.5 2.3 -2.2 -2.0 -1.9
Stomach or abdominal pain in last month 2.3 2.9 5.9 -2.2 -2.0 -1.6 -2.2 -1.7 -1.6 -1.8 0.5 -1.6 -2.0 -2.1 -1.1 -1.9 -2.4 -2.0 -1.5 -1.0 -2.2 -2.0 -0.0 -1.4 -0.7 -0.6
Supplements: Glucosamine 4.7 6.2 12.1 -2.8 -2.6 -1.5 -2.7 -2.1 -2.6 -2.8 -1.5 -1.4 -2.0 -2.2 -2.7 -2.2 -2.6 -1.9 -3.3 -3.5 -1.9 0.5 2.8 -2.5 -3.3 -3.2
Diverticular disease/diverticulitis (self-reported) 1.8 2.1 5.2 -1.6 -1.5 -1.7 -1.6 -1.5 -1.0 -0.1 -0.7 -2.1 -2.3 -1.3 0.3 -0.3 -2.0 -1.3 -0.8 -1.4 -1.4 -0.7 1.7 -1.6 -2.2 -1.5
Medication: Atenolol 0.3 0.3 2.6 -0.2 -0.5 0.3 -0.5 -0.4 -0.1 0.1 0.6 0.3 -0.3 -0.2 -1.3 -0.5 -0.2 -0.5 0.4 1.6 -0.6 -0.3 0.3 -0.3 1.0 -0.1
Medication: Levothyroxine sodium 0.7 1.1 8.5 -0.1 0.2 -1.5 0.1 0.4 0.1 0.5 -0.5 -1.5 -1.0 -0.3 -2.9 -1.3 -0.9 -0.1 -1.1 -1.9 -0.2 -1.0 0.6 0.4 -1.4 -0.5
Sitting height 0.2 1.3 3.8 1.1 1.6 1.0 1.7 1.5 1.4 1.9 -0.6 1.3 1.2 1.3 1.4 1.0 0.8 0.7 0.2 0.1 0.6 1.6 0.5 1.0 1.1 0.6
Chronic bronchitis/emphysema (father) 0.2 0.2 1.4 0.5 -0.1 0.4 -0.1 -0.0 -0.0 0.9 -1.2 0.3 0.1 0.2 -1.0 -0.3 0.1 -0.5 0.2 0.5 -0.3 0.2 0.2 -0.3 -0.0 -0.0
High blood pressure (mother) 0.2 0.3 1.5 0.1 0.9 0.1 0.7 1.0 1.2 -0.0 0.7 0.0 0.1 0.3 -0.1 0.5 0.6 0.7 0.4 0.3 0.7 0.3 -0.4 0.9 0.3 0.1
Body mass index (BMI) 1.2 5.2 15.4 -3.4 -1.0 -2.4 -1.6 -0.9 -1.8 -1.3 1.2 -3.2 -3.2 -2.5 -3.9 -2.0 -3.3 -2.5 -1.5 -1.2 -2.6 -2.3 1.2 -0.8 -2.1 -2.5
Impedance of leg (left) 0.2 0.8 5.1 1.2 -1.2 1.1 -0.8 -1.4 0.0 0.4 -0.6 1.3 1.0 0.2 2.2 1.1 0.8 0.1 0.1 0.2 0.1 0.6 -0.4 -1.2 0.5 0.1
Leg predicted mass (left) 0.3 1.5 5.2 -2.0 0.1 -1.1 -0.3 0.3 -0.6 -0.7 0.2 -1.3 -1.5 -1.2 -2.3 -1.4 -1.8 -1.2 -1.3 -1.3 -1.3 -0.1 1.5 0.0 -1.0 -1.6
Trunk fat mass 1.1 4.7 10.7 -3.2 -1.5 -1.7 -2.0 -1.4 -1.7 -1.5 0.5 -2.3 -2.8 -2.5 -2.9 -1.3 -3.2 -2.8 -1.9 -1.5 -2.9 -1.2 1.8 -1.4 -1.9 -3.3
Waist circumference 1.6 6.0 15.2 -3.9 -1.5 -2.3 -2.0 -1.3 -1.7 -1.3 0.1 -2.8 -3.3 -2.8 -2.8 -1.1 -3.7 -2.9 -2.2 -2.4 -3.0 -1.1 2.0 -1.4 -2.8 -3.4
Number of incorrect matches in round 0.4 0.7 2.5 1.1 0.9 0.7 1.0 0.7 1.6 0.9 0.2 0.4 1.0 1.5 0.3 0.1 0.9 0.6 1.4 0.6 0.8 0.1 -0.1 0.5 0.2 0.8
Past tobacco smoking 0.4 0.8 2.5 0.1 -1.0 1.1 -0.5 -0.9 -0.3 -1.6 -1.2 1.4 1.1 -0.8 -0.1 -0.6 0.4 -0.7 -1.4 -0.6 -0.5 0.7 1.4 -1.0 -0.1 -0.7
Alcohol usually taken with meals 0.4 0.7 4.3 0.2 1.0 0.1 0.9 1.2 0.7 0.4 -0.2 0.4 0.5 0.8 2.1 1.7 0.5 0.8 0.1 -0.1 0.9 0.0 0.1 0.9 -0.1 0.5
Nervous feelings 0.8 1.6 4.5 -1.2 -1.7 -0.6 -1.7 -1.4 -1.0 -1.0 -0.2 -0.5 -1.3 -1.3 -0.7 -2.1 -1.5 -1.3 -1.6 -1.8 -1.6 -0.7 0.1 -1.5 -0.6 -0.6
Frequency of tenseness / restlessness in last 2 weeks 0.2 0.4 2.5 -0.5 -0.2 0.1 -0.2 -0.2 -0.5 -0.2 1.5 -0.1 0.4 -0.5 -1.6 -0.6 -0.3 -0.4 -0.8 -0.6 -0.4 0.0 -0.3 -0.1 -0.6 0.1
Hearing difficulty/problems with background noise 0.5 0.8 5.4 0.5 -0.7 -1.7 -0.7 -0.5 0.6 0.3 -0.5 -1.6 -1.5 0.5 0.6 -0.4 -0.6 0.7 0.2 -0.8 0.4 -2.3 0.1 -0.5 -1.0 0.8
Hair/balding pattern: Pattern 2 0.2 0.3 1.8 0.2 0.1 1.0 0.1 0.2 0.6 0.1 -0.1 0.8 0.8 0.1 0.3 0.9 0.5 -0.2 -0.0 0.7 -0.1 1.3 0.0 -0.0 1.0 0.4
Had menopause 0.3 0.4 1.9 -0.6 1.4 -0.6 0.9 0.9 -0.2 -0.6 -1.0 -0.5 -0.0 0.0 -1.0 0.3 -0.2 0.0 -0.0 -0.2 0.2 0.6 0.3 1.1 0.1 -1.2
Had other major operations 0.5 0.6 2.9 -0.2 0.3 -1.7 0.1 0.3 0.4 -1.1 -0.2 -1.5 -0.6 -0.8 -0.9 -0.4 -0.8 0.2 -0.6 -1.2 0.1 -1.3 -0.3 0.6 -0.5 -0.5
Forced vital capacity (FVC) 0.4 1.7 11.5 -0.2 -0.6 3.4 -0.4 -0.8 -1.2 -0.7 -0.5 3.1 1.5 -0.4 1.1 0.5 1.2 -0.9 -0.5 0.4 -0.7 2.2 0.7 -1.2 -0.3 0.8
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.3 4.8 -1.4 -0.2 -1.6 -0.4 -0.4 -0.9 0.0 -1.4 -2.2 -1.6 -0.2 -1.7 -0.5 -1.2 -0.6 0.1 -0.7 -0.5 -0.4 1.5 -0.3 -2.0 -1.3
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 4.2 -0.1 0.8 -1.1 0.8 0.3 0.7 0.2 0.8 -0.8 -0.3 0.1 -0.1 0.7 -0.3 0.3 -0.9 -1.4 0.2 -0.5 -2.1 0.5 0.2 0.1
Qualifications: None of the above 0.9 1.9 8.6 0.6 0.5 -2.2 0.3 0.5 1.1 1.2 2.6 -2.4 -1.4 0.1 -1.2 -0.0 -1.0 -0.0 0.0 -0.6 -0.2 -2.9 -2.8 0.5 0.1 -1.0
Financial difficulties in last 2 years 1.4 1.9 8.1 -1.3 -2.3 -0.2 -1.7 -1.8 -0.9 -0.7 2.8 -1.1 -0.6 -1.7 -1.0 -1.7 -1.4 -1.3 0.8 1.7 -1.7 -0.7 -1.1 -1.4 0.3 -0.0
Mouth/teeth dental problems 0.5 0.8 3.9 0.0 0.5 1.8 0.7 0.5 -0.4 -0.5 0.1 2.0 1.5 1.0 0.2 0.9 1.1 -0.1 0.1 1.3 0.2 1.4 -0.1 0.1 1.2 -0.4
Heart attack 0.6 0.7 2.1 -1.0 -1.4 0.3 -1.5 -1.2 0.2 0.0 1.4 0.2 -1.0 -1.1 -0.1 -0.7 -0.8 -1.0 -0.1 0.6 -1.2 -0.0 -0.1 -1.1 0.1 -0.0
Allergy 0.4 0.9 3.0 -0.8 -0.1 -1.5 -0.5 -0.2 -0.3 -0.6 -0.4 -1.3 -1.3 -1.4 0.9 -0.5 -1.4 -0.6 -0.4 -1.7 -0.7 -0.4 1.2 -0.2 -1.2 -0.8
Pain all over the body in last month 1.0 1.0 4.3 1.2 0.5 1.5 0.5 0.6 0.5 -0.0 0.7 1.9 1.5 0.5 -0.6 -0.2 1.4 0.8 0.3 1.0 0.8 1.2 -1.1 0.5 2.1 0.9
Diabetes (self-reported) 0.7 1.0 3.7 -1.1 -0.7 0.4 -0.8 -0.6 -1.3 -1.4 1.0 -0.2 -0.4 -1.9 -0.6 -0.3 -0.9 -1.5 -1.5 -1.3 -1.6 0.0 0.1 -0.7 -0.9 -0.9
Hayfever/allergic rhinitis (self-reported) 0.2 0.3 2.6 0.4 -0.3 -0.1 -0.1 -0.6 -0.6 -1.1 -0.4 -0.3 0.1 -0.9 0.1 -0.6 0.1 -0.2 -0.4 -0.4 -0.0 -1.6 -0.1 -0.6 -0.5 -0.3
Medication: Ramipril 1.3 1.7 5.4 1.5 0.4 2.3 0.7 0.2 1.2 1.0 -0.4 2.3 1.7 1.5 1.3 -0.1 1.7 0.7 2.3 1.5 0.6 1.9 0.1 0.0 0.5 1.0
Medication: Simvastatin 0.6 0.9 2.9 -0.8 -0.9 -1.0 -1.0 -1.2 0.0 -0.2 -0.5 -1.2 -1.6 -0.7 0.1 -0.9 -1.2 -0.5 -0.8 -1.6 -0.8 -0.9 0.6 -1.2 -1.7 0.4
Fluid intelligence score 1.2 2.4 5.5 1.8 2.1 1.2 2.4 1.7 1.4 1.1 -0.0 1.6 1.4 1.8 0.8 1.2 2.2 2.2 1.5 0.6 2.2 1.2 -0.6 1.5 0.2 1.8
Illnesses of siblings 1.8 2.5 5.6 1.9 1.1 0.8 1.4 0.8 2.2 0.3 -0.6 1.0 1.7 2.0 2.3 2.4 2.2 2.3 1.9 1.0 2.3 1.4 -0.3 0.9 1.3 1.1
Neuroticism score 0.4 0.9 6.6 -0.9 -0.4 0.3 -0.3 -0.3 -1.0 -1.0 1.1 -0.2 0.1 -1.0 -2.6 -2.1 -0.6 -1.0 -0.8 -0.4 -1.0 -0.8 -0.1 -0.4 -0.6 -0.4
Weight 0.7 3.3 8.1 -2.7 -0.5 -2.0 -1.0 -0.4 -1.2 -0.7 0.6 -2.5 -2.6 -2.0 -2.9 -1.5 -2.9 -2.0 -1.5 -1.5 -2.2 -1.4 1.3 -0.5 -1.6 -2.3
Impedance of arm (right) 0.5 2.1 9.4 1.7 0.1 2.1 0.4 0.1 0.5 0.0 -0.1 2.3 1.9 1.1 3.1 2.2 2.1 1.3 1.3 0.8 1.3 2.2 -0.4 0.2 1.1 0.2
Arm fat percentage (right) 1.1 4.5 11.2 -3.1 -1.0 -2.3 -1.6 -0.9 -1.7 -1.5 0.6 -2.9 -3.0 -2.2 -3.0 -1.0 -3.0 -2.4 -1.3 -1.3 -2.4 -1.6 1.4 -0.7 -2.2 -3.4
Trunk fat-free mass 0.2 1.0 4.4 -0.8 0.8 -1.6 0.5 0.7 0.3 0.3 -0.5 -1.4 -1.2 -0.5 -2.1 -1.3 -1.3 -0.4 -1.2 -1.7 -0.5 -0.4 0.6 0.4 -0.8 -0.7
Hip circumference 0.9 4.1 12.0 -3.5 -1.1 -2.0 -1.6 -0.8 -1.5 -1.2 0.4 -2.6 -2.8 -2.2 -3.1 -1.2 -3.1 -2.3 -1.2 -0.9 -2.4 -1.7 1.3 -0.9 -1.4 -2.9
Time employed in main current job 1.4 1.6 3.8 -1.5 -1.8 -0.8 -1.7 -1.0 -1.7 -1.6 0.1 -0.6 -1.7 -1.5 0.1 -1.6 -1.4 -1.4 -2.0 -1.3 -1.4 -0.1 0.6 -1.0 -0.7 -0.7
Alcohol intake versus 10 years previously 0.1 0.2 1.4 -0.3 0.1 0.2 -0.1 -0.0 -0.1 -0.2 1.2 -0.1 0.0 -0.1 -0.1 0.9 -0.4 -0.7 -0.2 -0.1 -0.7 0.7 -0.6 -0.0 0.1 -0.2
Father’s age at death 1.0 1.3 6.7 0.1 -0.6 2.3 -0.4 -0.9 -1.6 -2.0 -0.2 2.6 1.5 -0.4 -0.3 -0.1 1.1 -0.3 -1.4 -1.0 -0.1 1.5 0.7 -1.1 0.4 0.0
Worrier / anxious feelings 0.9 1.8 9.7 -1.6 -0.2 -1.9 -0.7 -0.3 -0.5 -1.0 1.1 -1.4 -1.7 -1.4 -1.6 -1.3 -1.5 -0.4 -2.4 -3.1 -0.7 -0.1 -0.1 0.0 -1.3 -0.6
Frequency of tiredness / lethargy in last 2 weeks 0.6 1.0 3.4 -0.5 -0.3 -1.0 -0.5 -0.7 -0.1 0.1 0.5 -1.2 -1.2 -1.0 -1.8 -1.2 -1.3 -0.9 -1.4 -1.8 -1.1 -1.0 0.2 -0.7 -1.0 -0.6
Falls in the last year 0.9 1.2 4.5 -1.6 -0.7 -2.1 -0.8 -0.4 -0.4 -0.0 -0.4 -1.5 -2.1 -0.2 -2.1 -1.5 -1.8 -0.7 -1.0 -0.4 -0.8 0.4 0.0 -0.1 0.6 -0.8
Hair/balding pattern: Pattern 3 0.6 0.9 4.1 0.7 0.9 -2.0 0.7 1.1 0.5 0.6 0.6 -1.6 -1.0 0.4 0.1 -0.9 -0.3 1.0 0.6 -0.2 0.8 -1.7 -1.0 1.3 0.7 0.5
Number of live births 0.2 0.2 1.0 0.4 -0.4 0.6 -0.1 -0.5 -0.3 0.4 -0.3 -0.1 0.1 -0.5 -0.6 -0.9 -0.0 -0.4 1.0 0.3 -0.4 -0.7 0.2 -0.4 -1.0 -0.1
Forced expiratory volume in 1-second (FEV1) 0.5 1.6 10.8 -0.1 -0.7 3.3 -0.3 -0.8 -1.0 -0.9 -0.6 2.8 1.5 -0.5 1.6 1.0 1.2 -0.7 -0.5 0.2 -0.4 1.4 1.1 -1.2 -0.9 0.7
Pulse rate 0.5 0.9 2.4 -0.7 -0.9 -0.8 -1.0 -0.7 -0.8 -0.4 -0.2 -1.0 -1.5 -1.4 -1.2 -1.0 -1.2 -1.0 -0.4 -0.7 -1.1 -0.9 -0.0 -0.5 -1.5 -0.4
Happiness 0.2 0.2 1.0 -0.2 -0.5 0.0 -0.2 -0.5 -0.2 0.2 -0.2 -0.1 -0.3 -0.5 -0.3 -1.0 -0.5 -0.5 -0.2 -0.4 -0.5 -0.0 0.4 -0.8 -0.7 0.3
Noisy workplace 0.5 0.6 5.6 -0.8 -0.0 -0.3 -0.2 -0.4 -0.9 -0.2 2.4 -0.6 0.2 -0.5 0.3 0.0 -0.7 -0.7 -1.4 -0.7 -0.8 -0.0 -0.3 -0.2 -0.8 0.1
Qualifications: A levels/AS levels or equivalent 1.6 3.5 9.9 1.2 1.4 2.9 1.8 1.7 1.0 -0.7 -2.4 3.1 2.6 1.5 1.5 2.0 2.9 1.5 1.5 2.4 2.0 1.7 1.0 1.3 1.5 0.9
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 1.7 -0.1 -0.1 1.2 0.1 -0.2 0.2 -0.4 -0.9 1.3 0.7 0.4 -0.5 -0.2 0.5 -0.0 0.4 0.7 0.1 0.8 -0.3 -0.2 0.5 0.2
Mouth/teeth dental problems: Dentures 1.4 2.4 12.1 -1.0 -0.8 -3.2 -1.1 -0.9 -0.0 0.6 1.2 -3.5 -2.8 -1.4 -0.6 -1.4 -2.3 -0.7 0.1 -0.5 -1.0 -2.4 -0.8 -0.6 -0.3 -0.2
Asthma 1.6 3.2 5.6 2.4 2.3 1.1 2.4 2.1 1.8 2.0 -0.1 1.2 2.1 2.1 0.7 1.1 2.3 2.1 1.4 1.6 2.2 1.0 -1.9 2.1 1.4 1.4
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.6 2.3 -0.3 -0.7 1.0 -0.5 -0.5 -1.5 -0.1 0.5 0.7 0.0 -0.6 -1.1 -1.4 0.2 -0.4 -1.3 0.1 -0.4 -0.3 0.5 -0.8 -0.7 1.0
Medication: Cholesterol lowering 0.5 0.8 4.4 -0.3 -0.8 -0.2 -0.8 -0.8 -0.3 -1.3 -1.0 -0.8 -1.0 -0.6 0.8 0.1 -0.5 -0.4 0.1 -0.8 -0.5 -1.6 1.3 -1.0 -2.1 -0.8
Depression (self-reported) 0.6 0.7 3.4 1.1 0.4 0.1 0.6 0.3 1.2 1.8 0.0 0.0 0.6 1.5 0.4 0.3 0.6 0.9 0.7 0.3 0.8 -0.1 -0.4 0.4 0.7 1.8
Medication: Lansoprazole 0.5 0.6 2.6 -0.1 -0.6 1.1 -0.4 -0.5 -0.3 -0.5 -0.9 1.4 0.7 -0.4 0.1 0.1 0.1 -0.6 -0.9 -0.8 -0.6 1.6 1.3 -0.8 -0.2 0.4
Prospective memory result 0.6 0.8 5.3 -0.1 -0.8 -0.2 -0.6 -0.8 -0.6 -2.0 0.2 -1.5 -0.1 -0.6 -0.8 -1.0 -0.0 -0.1 0.8 1.3 0.0 -2.3 0.2 -0.7 -0.3 -0.0
Lung cancer (father) 0.3 0.4 2.2 -0.1 -0.3 -0.3 -0.6 -0.6 -0.1 -0.0 1.0 -1.0 -0.8 -0.7 -0.4 -0.5 -0.5 -0.6 0.8 0.1 -0.6 -1.5 -0.4 -0.5 -0.5 -0.3
Illnesses of mother 0.7 0.8 3.4 -0.4 -1.2 -0.2 -1.1 -1.4 -1.0 -0.1 -1.8 -0.4 -0.6 -0.2 -0.1 -0.9 -0.8 -0.9 -0.6 -0.7 -0.9 -0.5 1.3 -1.2 -1.2 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.3 9.1 0.3 0.1 3.0 0.4 0.1 -0.2 -0.7 -0.5 2.6 1.8 0.3 0.8 0.8 1.6 -0.1 -0.0 0.7 0.3 1.4 1.1 -0.4 -0.3 1.0
Pulse wave Arterial Stiffness index 0.3 0.4 1.9 -0.4 -0.2 -1.4 -0.2 0.0 -0.4 -0.0 0.3 -1.2 -1.1 -0.3 -0.1 -0.8 -0.8 -0.1 0.4 0.2 -0.2 -1.2 0.7 -0.1 -0.2 -0.5
Impedance of arm (left) 0.4 2.0 6.3 1.4 -0.3 2.4 -0.0 -0.3 0.2 -0.3 -0.2 2.5 2.1 1.0 2.5 2.0 2.1 1.0 1.0 1.1 1.2 2.3 -0.3 -0.3 1.4 0.4
Arm fat mass (right) 1.2 4.9 12.0 -3.3 -0.9 -2.5 -1.6 -0.8 -1.4 -1.1 0.5 -3.1 -3.2 -2.2 -3.5 -1.4 -3.3 -2.4 -1.5 -1.8 -2.5 -1.7 1.5 -0.7 -2.2 -3.2
Trunk predicted mass 0.2 1.0 4.2 -0.7 0.8 -1.6 0.5 0.8 0.4 0.4 -0.4 -1.4 -1.2 -0.5 -2.0 -1.3 -1.3 -0.3 -1.2 -1.7 -0.4 -0.4 0.5 0.5 -0.8 -0.7
Standing height 0.1 1.2 4.0 1.4 1.0 0.7 1.1 0.8 1.3 1.6 -1.3 1.4 1.0 1.1 1.9 1.0 0.8 0.8 -0.1 -0.7 0.8 2.0 0.2 0.3 1.0 0.3
Length of working week for main job 1.1 1.3 4.2 -0.4 -1.5 0.7 -1.3 -1.9 -1.7 -2.0 1.1 -0.0 0.5 -1.8 -0.1 -1.2 -0.1 -0.9 -0.4 0.4 -0.9 -0.9 -0.1 -2.0 -1.0 0.1
Exposure to tobacco smoke at home 0.3 0.4 2.4 -0.8 -0.0 -0.1 -0.1 0.2 -0.6 -0.6 0.1 -0.7 -0.4 -0.8 -1.4 -1.5 -0.6 -0.8 -0.4 -0.0 -0.8 -0.3 0.2 -0.0 -0.6 -0.3
Breastfed as a baby 0.5 0.7 2.1 0.5 0.7 1.2 0.7 0.7 0.7 -0.8 -1.4 0.9 1.3 0.6 -0.9 -0.5 1.0 0.5 0.7 -0.0 0.7 0.8 1.0 0.6 -0.4 -0.2
Tense / ‘highly strung’ 0.3 0.5 3.7 0.1 -0.2 1.0 0.1 0.3 -0.5 -1.0 1.9 0.8 0.9 -0.7 -1.0 -1.4 0.3 -0.4 0.2 0.4 -0.4 -0.7 -0.1 -0.0 -0.3 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.1 1.7 4.5 1.4 1.0 1.3 1.3 0.9 1.0 1.4 1.2 0.9 1.6 1.8 -0.5 0.7 1.8 1.8 1.3 0.5 1.7 0.9 -1.1 1.0 0.6 2.1
Hair/balding pattern: Pattern 4 0.1 0.2 1.2 -0.7 -0.1 -0.6 -0.1 -0.2 -0.1 0.3 0.7 -0.6 -0.3 0.1 0.1 1.1 -0.6 -0.2 0.3 -0.0 -0.3 -0.2 -0.3 0.2 -0.6 -0.1
Birth weight of first child 0.3 0.6 3.0 0.8 -0.1 1.3 0.3 0.1 -0.8 0.1 -0.7 1.0 0.6 0.7 0.1 0.1 1.0 0.4 0.3 1.7 0.5 -0.7 0.4 -0.3 1.2 0.9
Peak expiratory flow (PEF) 0.2 0.5 3.0 0.1 -0.1 1.7 0.1 -0.1 -0.4 -0.4 0.5 1.5 0.8 -0.8 0.9 0.9 0.7 -0.3 -0.1 -0.1 -0.2 0.5 0.2 -0.3 -0.8 0.7
Pulse wave reflection index 0.8 1.0 3.0 1.3 1.7 -0.5 1.6 1.2 0.6 1.0 -0.7 -0.5 0.4 1.3 -0.2 0.2 0.9 1.2 1.3 0.9 1.3 -1.1 0.0 1.1 0.5 0.3
Ever highly irritable/argumentative for 2 days 0.6 0.7 2.7 -1.6 -0.6 -0.3 -0.6 -0.7 -0.9 -0.4 0.8 -0.5 -1.0 -1.0 -1.5 -1.3 -0.8 -0.8 -1.0 0.3 -1.0 -0.1 -0.9 -0.3 0.2 0.3
Loud music exposure frequency 0.4 0.4 3.3 -0.9 -0.8 -0.0 -0.7 -0.7 -0.9 0.1 1.8 -0.3 0.0 -0.5 0.6 -0.3 -0.7 -0.5 -0.1 -0.1 -0.7 -0.0 -0.4 -0.5 0.1 -0.7
Qualifications: O levels/GCSEs or equivalent 0.9 1.5 4.5 0.3 0.6 1.4 0.9 0.6 0.7 0.1 -1.7 1.7 1.8 1.1 1.1 1.3 1.4 0.9 0.7 1.6 1.1 2.1 1.5 0.6 1.3 0.8
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 2.5 0.3 0.1 -0.2 0.2 0.3 0.8 -0.1 1.0 -0.1 0.3 0.0 1.6 1.0 0.7 1.4 1.0 -0.5 1.2 -0.1 -0.2 0.6 -0.8 0.7
Blood clot in the leg (DVT) 1.0 1.3 4.0 1.7 -0.2 1.7 0.1 -0.4 0.6 0.6 1.4 1.8 1.4 0.9 -0.5 0.6 1.5 0.8 0.4 1.0 0.7 1.2 -1.3 -0.4 1.7 2.0
Medication: Paracetamol 0.8 1.3 8.1 -0.2 -0.4 0.4 -0.2 -0.3 0.3 -1.2 2.8 -0.3 0.2 -0.4 -0.5 -0.1 0.5 0.3 1.3 2.1 0.2 -2.4 -1.7 -0.3 1.0 1.9
Headache pain in last month 1.4 2.4 9.1 -2.1 -1.5 0.2 -1.3 -1.4 -1.8 -3.0 -1.0 -0.7 -0.6 -1.2 -0.5 -0.8 -1.1 -1.8 -0.3 -0.4 -1.6 -0.6 2.7 -1.4 -2.6 -1.9
Medication for cholesterol, blood pressure or diabetes 0.2 0.4 1.6 -0.8 -0.3 -0.2 -0.3 -0.4 -1.2 -0.2 0.1 0.1 0.0 -0.8 -0.9 -0.8 -0.5 -0.6 -1.3 -0.1 -0.5 0.8 0.4 -0.3 0.6 -0.0
Glaucoma (self-reported) 2.0 2.3 8.1 -1.8 -1.6 1.9 -1.3 -1.5 -1.6 -2.4 -1.1 1.5 0.5 -1.8 0.1 -1.4 -0.5 -2.0 -0.1 0.3 -1.8 1.5 2.8 -1.5 -1.4 -1.1
Gout (self-reported) 0.2 0.3 1.3 -0.6 0.1 -0.7 -0.3 -0.2 -0.5 0.3 -0.7 -0.1 -0.7 0.3 1.0 0.8 -0.6 -0.4 -0.1 -0.3 -0.4 1.1 -0.0 -0.0 0.3 -0.9
Hypothyroidism/myxoedema (self-reported) 0.4 0.7 3.6 0.6 0.4 -0.8 0.5 0.7 0.1 1.3 -0.9 -0.8 -0.0 0.6 -1.9 -1.1 -0.1 0.4 -0.7 -1.3 0.3 -0.9 0.8 0.6 -1.1 0.3
Medication: Amlodipine 0.9 1.3 3.2 1.1 0.9 0.3 1.0 1.3 1.5 0.8 1.0 0.8 1.1 1.8 1.2 0.9 1.4 1.4 0.5 0.6 1.4 1.0 -1.2 1.1 1.5 1.5
Medication: Ventolin 100micrograms inhaler 0.3 0.3 1.4 0.3 -0.9 0.8 -0.6 -1.0 -0.1 -0.3 0.6 0.1 0.2 -0.3 -0.3 -0.1 0.4 -0.2 -0.8 0.4 -0.2 -1.1 -0.2 -1.2 -0.2 0.4
Birth weight 0.7 1.5 8.2 -0.3 -0.7 2.5 -0.5 -0.4 -1.1 -0.5 -1.0 2.3 0.9 -1.6 -0.7 -0.5 0.1 -1.4 -1.6 -0.3 -1.3 2.9 0.7 -0.8 -0.4 -0.5
Chronic bronchitis/emphysema (mother) 0.2 0.2 1.2 0.3 0.5 -0.3 0.5 0.9 -0.3 -0.1 0.1 -0.2 -0.2 0.1 -1.1 -0.5 0.3 0.3 0.5 0.6 0.3 -0.6 -0.3 0.8 -0.0 0.4
High blood pressure (siblings) 1.4 1.9 4.5 -1.0 -0.9 -1.4 -1.3 -0.7 -1.6 -0.4 1.0 -1.4 -1.7 -1.9 -1.9 -2.1 -1.9 -1.6 -1.5 -1.3 -1.8 -1.8 -0.3 -0.5 -0.9 -0.7
Forced vital capacity (FVC), Best measure 0.4 1.5 10.8 0.5 0.1 3.3 0.4 0.1 -0.1 -0.2 -0.1 3.0 2.0 0.3 0.6 0.5 1.7 -0.2 -0.3 0.7 0.1 1.9 0.5 -0.5 0.4 1.3
Body fat percentage 1.5 5.9 12.6 -3.5 -1.8 -2.1 -2.3 -1.7 -2.2 -1.8 0.8 -2.7 -3.1 -2.8 -2.9 -1.2 -3.5 -3.1 -1.8 -1.4 -3.2 -1.7 1.7 -1.5 -2.2 -3.5
Leg fat percentage (right) 1.9 6.8 14.4 -3.8 -2.0 -2.4 -2.4 -1.8 -2.2 -1.4 1.0 -3.2 -3.5 -3.0 -3.3 -1.5 -3.8 -3.2 -2.0 -1.5 -3.3 -2.2 1.4 -1.6 -2.6 -3.4
Arm fat-free mass (right) 0.5 2.4 8.1 -1.9 -0.1 -2.0 -0.5 -0.2 -0.4 -0.1 -0.2 -2.1 -2.1 -1.4 -2.9 -1.9 -2.4 -1.5 -1.6 -1.7 -1.6 -1.2 1.1 -0.4 -1.4 -1.6
Exposure to tobacco smoke outside home 0.4 0.5 1.5 -1.1 -0.1 -0.8 -0.2 -0.3 -0.8 -0.9 0.2 -0.9 -0.7 -0.6 -0.6 -0.3 -0.9 -0.7 -1.0 -1.0 -0.6 -0.5 0.5 -0.2 -0.8 -1.2
Comparative body size at age 10 0.5 1.4 3.6 -1.6 0.9 -1.7 0.0 1.0 -0.4 0.8 1.1 -1.7 -1.8 0.1 -1.2 -0.7 -1.7 -1.7 -1.0 -0.5 -1.6 -0.6 -1.4 0.7 -0.4 -1.9
Number of full brothers 1.2 1.5 5.8 -0.0 -0.8 -2.4 -1.4 -1.1 -0.7 1.1 -0.1 -2.2 -2.3 -0.8 0.4 -1.3 -1.6 -0.7 -0.4 -1.7 -1.0 -1.1 -1.1 -1.0 -1.0 -0.0
Worry too long after embarrassment 0.2 0.3 1.1 -0.4 0.9 0.4 0.7 0.7 0.0 -1.1 -0.5 0.2 0.6 -0.0 -0.2 -0.4 0.4 0.2 0.8 0.2 0.5 0.1 0.8 0.7 -0.5 -0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 2.3 0.8 -0.2 0.9 0.2 -0.3 0.7 1.5 1.2 0.4 1.0 -0.1 0.5 1.0 0.2 0.1 -0.4 -0.4 -0.1 -0.3 -1.0 -0.4 -0.4 1.4
Wheeze or whistling in the chest in last year 0.6 1.1 2.8 -0.1 1.1 -0.7 1.0 1.2 1.0 1.3 1.7 -0.7 -0.3 0.9 -1.5 0.1 0.3 1.0 0.8 1.3 0.8 -0.2 -1.5 1.6 1.6 1.0
Number of children fathered 1.5 1.7 3.9 1.4 1.2 1.4 1.4 1.0 1.6 1.2 2.0 1.0 1.6 1.3 0.6 0.2 1.6 1.4 1.6 1.6 1.2 0.6 -1.1 1.0 0.8 1.9
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 3.3 0.8 -0.3 -0.2 -0.1 0.0 -0.3 1.4 0.6 -0.1 -0.3 -0.0 -1.2 -1.8 -0.1 -0.1 -1.5 -1.1 -0.3 -0.8 -1.0 -0.4 0.3 1.1
Age at first live birth 2.2 3.9 8.1 1.7 2.1 1.8 2.0 1.6 1.7 1.0 -1.1 2.7 2.1 1.9 2.2 1.7 2.6 2.1 1.6 2.5 2.3 2.0 -1.3 1.5 2.8 1.8
Pulse wave peak to peak time 0.4 0.4 1.9 0.4 0.1 1.4 0.1 -0.1 0.4 0.0 -0.3 1.3 1.1 0.2 0.4 0.9 0.7 0.1 -0.6 -0.4 0.2 1.3 -0.7 -0.1 0.1 0.5
Health satisfaction 1.9 2.4 7.1 -1.5 -2.0 0.3 -2.0 -2.1 -1.1 -1.9 -0.5 -0.7 -0.2 -2.7 -1.2 -1.1 -1.6 -2.2 -0.8 -0.8 -2.2 -0.9 0.6 -2.0 -1.7 -2.1
Shortness of breath walking on level ground 0.6 0.7 6.2 0.0 0.5 1.1 0.3 0.4 0.9 -0.7 0.3 1.6 1.1 -0.3 -0.5 0.2 0.5 -0.5 -1.1 -0.8 -0.4 2.5 0.3 0.4 -0.3 -0.7
Qualifications: College or University degree 2.6 8.2 29.4 2.5 1.7 5.2 2.3 1.9 2.1 0.2 -2.1 5.4 4.4 2.5 3.5 3.4 4.3 2.2 1.6 2.5 2.6 2.1 0.7 1.4 1.6 2.5
Eye problems/disorders: None of the above 0.2 0.3 1.6 0.0 0.6 -1.3 0.2 0.2 -0.2 0.7 0.3 -0.9 -1.2 0.2 -0.2 0.0 -0.3 0.5 0.2 -0.4 0.3 -0.2 -0.8 0.3 0.2 -0.2
Mouth/teeth dental problems: Loose teeth 0.8 1.0 4.1 -0.9 -0.6 -1.9 -0.8 -0.7 -0.1 1.5 0.8 -2.0 -1.7 -0.3 -0.6 -1.4 -1.4 -0.2 0.4 -0.3 -0.5 -0.7 -0.2 -0.7 -0.5 0.1
Emphysema/chronic bronchitis 0.2 0.2 1.1 -0.4 0.2 -0.6 0.2 0.5 -0.3 0.3 0.5 -0.8 -0.3 -0.1 -0.1 0.1 -0.2 0.2 0.6 0.9 0.1 -1.0 0.1 0.4 -0.2 0.8
Medication for pain relief, constipation, heartburn 0.6 1.1 4.8 0.8 0.4 -1.0 0.4 0.4 0.3 1.5 -2.1 -0.2 -0.1 0.8 1.9 1.6 -0.1 0.8 -0.1 -1.8 0.7 2.2 0.1 0.4 0.0 -0.6
Neck or shoulder pain in last month 0.9 1.2 5.5 -0.3 -0.4 -2.3 -0.6 -0.2 -0.1 -0.6 0.2 -2.4 -1.5 -0.4 -1.0 -0.1 -1.4 -0.4 0.1 -1.0 -0.4 -2.3 -0.2 -0.0 -1.3 -1.4
Medication: Blood pressure 0.9 1.6 4.9 1.7 1.0 0.4 1.0 0.8 2.0 0.5 0.4 0.5 1.0 1.9 1.4 1.4 1.5 1.7 2.2 1.0 1.7 -0.4 -1.1 0.9 0.8 0.8
Angina (self-reported) 0.3 0.4 2.7 -0.2 0.3 -1.0 -0.1 0.4 0.1 0.4 -0.5 -0.9 -1.1 -0.4 -0.7 -1.6 -1.0 -0.6 -0.1 -0.3 -0.7 -0.7 -0.3 0.4 -0.6 -0.3
Migraine (self-reported) 2.0 2.5 7.7 -2.2 -1.4 -1.1 -1.5 -1.3 -1.7 -0.8 -1.5 -1.1 -1.7 -1.5 0.0 0.4 -2.1 -2.2 -1.2 -1.4 -2.0 0.3 1.5 -1.3 -2.2 -2.8
Medication: Ibuprofen 0.7 0.8 2.6 -0.3 -0.9 1.6 -0.7 -0.7 -1.5 -0.4 0.7 1.1 0.7 -1.1 -0.8 -1.4 0.3 -0.7 -1.1 0.5 -0.7 0.0 0.7 -1.0 -0.6 1.2
Medication: Allopurinol 0.2 0.3 1.1 -0.0 -0.1 0.6 -0.0 0.1 -0.3 0.8 -0.6 0.7 0.3 0.6 1.0 0.9 0.1 -0.5 0.5 1.0 -0.3 0.7 0.1 -0.1 0.9 -0.2
Medication: Omeprazole 1.2 1.4 3.7 -1.2 -1.1 -0.3 -1.3 -1.3 -0.7 -1.8 0.8 -0.6 -0.6 -1.0 -1.9 -1.6 -0.9 -0.9 -1.9 -1.3 -0.9 -1.7 0.3 -1.5 -0.9 0.1
Medication: Seretide 50 evohaler 0.2 0.2 1.1 0.2 -0.5 0.6 -0.6 -0.4 0.5 0.1 0.3 0.4 0.6 0.1 -1.1 0.1 0.2 -0.4 -0.7 0.4 -0.3 0.3 -1.0 -0.5 0.3 -0.2
Mean time to correctly identify matches 1.0 1.9 4.9 0.6 1.3 1.5 1.6 1.8 1.8 0.2 1.8 1.4 2.2 0.9 -0.8 -0.8 1.3 0.8 0.6 1.9 1.0 1.4 0.0 1.2 2.2 1.7
Heart disease (mother) 0.4 0.5 3.6 -0.0 0.9 -0.2 0.8 1.3 0.1 -0.0 1.2 0.1 0.0 0.5 -1.9 -0.8 0.4 0.8 0.1 -0.4 0.7 0.2 -0.6 1.0 0.4 0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.0 1.2 3.8 -1.3 -0.1 1.9 0.0 -0.4 -1.4 -1.6 -1.5 1.2 0.7 -0.8 -0.2 1.3 0.3 -0.9 1.4 1.3 -0.6 1.0 1.9 -0.5 -1.0 -1.3
Whole body fat mass 1.2 4.9 11.1 -3.3 -1.1 -2.2 -1.7 -1.1 -1.8 -1.4 0.6 -2.7 -3.0 -2.4 -3.1 -1.3 -3.3 -2.7 -1.8 -1.6 -2.8 -1.5 1.6 -1.0 -2.0 -3.2
Leg fat mass (right) 1.6 6.4 14.6 -3.8 -1.4 -2.5 -2.0 -1.2 -1.9 -1.6 0.7 -3.1 -3.4 -2.8 -3.4 -1.6 -3.8 -3.1 -2.2 -1.9 -3.1 -1.7 1.8 -1.1 -2.4 -3.6
Arm predicted mass (right) 0.5 2.4 6.8 -1.9 -0.2 -2.0 -0.5 -0.3 -0.3 0.1 -0.4 -2.1 -2.1 -1.4 -2.6 -1.8 -2.5 -1.6 -1.6 -1.9 -1.7 -1.0 1.3 -0.5 -1.6 -1.6
Pulse rate, automated reading 0.4 1.3 5.2 -1.5 -1.3 -0.2 -1.3 -1.5 -0.7 -1.0 0.6 -0.5 -1.0 -2.3 -0.8 -0.6 -1.4 -1.6 -1.1 -0.9 -1.6 0.5 0.1 -1.3 -1.1 -0.9
Alcohol intake frequency. 0.9 2.1 5.0 -1.5 -1.3 -2.0 -1.6 -1.3 -0.3 -1.6 0.3 -2.2 -2.1 -1.6 -1.1 -1.6 -1.8 -1.3 -0.7 -1.8 -1.3 -0.5 0.1 -1.0 -1.9 -1.9
Comparative height size at age 10 0.1 0.7 2.2 0.8 1.3 0.3 1.2 1.5 0.7 -0.1 -0.1 0.7 1.1 0.5 1.4 1.2 0.7 0.8 0.4 -0.1 0.8 0.9 0.0 1.2 0.3 -0.3
Number of full sisters 1.7 2.1 5.7 -0.8 -1.0 -1.9 -1.2 -1.1 -0.8 -0.5 1.0 -2.1 -2.0 -1.4 -1.1 -1.0 -2.0 -0.8 -0.9 -2.1 -1.0 -2.1 1.0 -0.9 -2.4 -1.4
Suffer from ‘nerves’ 0.7 1.1 2.7 -1.2 -1.0 -0.9 -1.0 -0.7 -1.2 -0.9 0.4 -1.0 -1.5 -1.0 -1.4 -1.6 -1.2 -1.1 -1.4 -1.2 -1.2 -0.3 0.6 -0.7 -0.6 -0.6
Overall health rating 1.5 3.2 7.1 -1.7 -1.1 -1.1 -1.3 -1.0 -1.4 -1.8 0.4 -1.6 -1.4 -2.4 -2.7 -2.1 -2.1 -2.0 -1.8 -2.6 -2.0 0.0 0.8 -1.1 -2.7 -2.5
Chest pain or discomfort 0.2 0.2 0.9 -0.6 0.2 -0.4 0.1 0.7 -0.0 0.4 0.8 -0.5 -0.5 0.1 -0.6 -0.1 -0.3 -0.1 -0.7 -0.6 -0.1 0.9 -0.4 0.7 -0.3 0.1
Had major operations 0.5 0.6 1.8 1.1 -0.7 0.8 -0.5 -0.5 0.7 1.0 -0.1 1.3 0.5 0.8 1.3 1.2 0.6 0.4 -0.8 -1.0 0.2 0.3 -0.8 -0.6 0.2 1.0
Age at last live birth 0.9 1.4 4.3 0.9 1.3 0.5 1.3 1.1 1.1 0.9 0.1 1.1 1.1 0.8 0.7 0.8 1.4 1.3 1.3 1.4 1.4 0.9 -1.7 1.2 2.1 1.1
Family relationship satisfaction 0.9 1.1 3.3 -1.0 -1.5 -0.5 -1.3 -1.5 -1.4 -0.7 -1.5 -0.9 -0.7 -1.0 0.0 -0.1 -0.9 -0.8 -0.5 -0.5 -0.8 -0.2 1.1 -1.6 -1.8 -0.9
Leg pain on walking 2.7 3.4 7.7 -2.8 -2.0 -1.6 -2.2 -2.1 -2.2 -1.3 1.3 -1.9 -2.0 -2.1 -0.9 -0.8 -2.5 -2.2 -1.7 -1.1 -2.2 -1.7 0.3 -1.8 -0.9 -2.3
Qualifications: NVQ or HND or HNC or equivalent 2.7 3.2 7.3 -2.0 -2.7 -1.8 -2.7 -2.4 -1.8 -1.7 0.5 -1.6 -1.9 -2.0 -0.6 -1.0 -2.1 -1.2 -1.9 -2.5 -1.4 0.4 0.9 -1.9 -2.1 -1.4
Commuting to job workplace: Car/motor vehicle 2.1 2.5 9.8 -1.7 -1.2 -1.1 -1.4 -1.2 -2.1 -3.1 -0.7 -1.3 -1.2 -1.8 -0.2 -1.4 -1.3 -1.3 -1.6 -1.9 -1.1 -1.5 0.7 -1.2 -2.1 -2.2
Illness, injury, bereavement, stress in last 2 years 1.1 1.3 3.7 1.4 1.9 0.5 1.6 1.4 0.8 0.4 -1.0 0.3 1.0 1.2 0.9 0.9 1.5 1.6 1.4 -0.1 1.7 0.2 1.1 1.1 -0.7 0.7
Medication: Aspirin 0.8 1.0 5.5 -1.3 -0.3 0.2 -0.6 -0.3 0.2 -0.5 0.1 -0.6 -0.9 -0.5 -2.4 -1.8 -0.9 -1.6 -0.1 0.8 -1.5 -1.4 0.7 -0.3 -0.9 -1.2
Supplements: Vitamin C 0.6 0.7 4.3 -0.6 -0.3 -0.9 -0.6 0.0 -0.0 -0.5 0.2 0.1 -0.9 -0.6 -2.1 -0.5 -0.8 -0.7 -1.6 -1.3 -0.5 0.7 -1.3 0.1 0.2 -0.7
Knee pain experienced in last month 1.0 1.6 4.6 -2.2 -1.2 -0.7 -1.3 -1.0 -0.9 -1.4 0.9 -1.1 -1.4 -1.2 -1.0 -0.9 -1.6 -1.6 -0.2 -0.6 -1.5 0.1 1.5 -0.9 -2.1 -1.2
Hypertension (Self-reported) 0.2 0.4 2.9 0.3 0.6 -0.3 0.3 0.4 1.4 1.7 0.7 -0.6 -0.5 0.6 0.4 -0.5 -0.1 0.3 0.6 0.4 0.1 -0.2 -1.2 0.3 -0.2 0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 3.2 0.8 -0.2 1.8 0.1 -0.3 0.3 -1.0 0.4 1.7 1.4 0.4 0.2 0.5 1.1 0.3 -0.3 -0.1 0.4 1.3 0.2 -0.4 0.4 0.3
Illnesses of father: Heart disease 3.0 4.1 12.5 -2.2 -1.7 -1.8 -2.1 -0.9 -2.2 -1.6 -1.7 -1.7 -2.7 -2.3 -0.9 -1.0 -2.3 -1.7 -2.5 -3.5 -1.8 -0.4 2.0 -1.4 -3.0 -2.3
Illnesses of siblings: Diabetes 0.3 0.4 1.5 -1.0 -0.5 1.2 -0.3 -0.1 -0.7 -0.7 0.4 0.6 0.4 -0.3 -0.6 0.4 -0.1 -1.0 -0.8 0.8 -0.8 -0.2 0.9 -0.5 -0.6 -0.1
Smoking status: Previous 0.2 0.4 1.9 -0.0 0.7 -0.4 0.3 0.5 -0.2 0.7 1.2 -0.8 -0.8 0.2 0.0 0.2 -0.0 0.5 0.6 0.4 0.3 -0.6 -1.4 0.6 0.2 0.7
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 4.6 0.0 -0.4 0.8 -0.4 -1.0 0.0 -0.2 -0.0 0.8 0.7 -0.4 0.3 0.4 -0.0 -0.6 -0.8 -1.1 -0.5 2.1 0.5 -1.2 -0.2 -0.9
Whole body fat-free mass 0.2 1.4 5.3 -1.5 0.4 -1.5 0.1 0.5 -0.1 -0.2 -0.2 -1.5 -1.5 -1.0 -2.3 -1.5 -1.7 -0.9 -1.3 -1.6 -1.0 -0.4 1.1 0.2 -1.1 -1.2
Leg fat-free mass (right) 0.2 0.8 2.8 -1.6 0.5 -0.9 0.1 0.7 -0.1 -0.3 0.1 -1.0 -1.2 -0.7 -1.7 -1.0 -1.3 -0.8 -0.8 -0.9 -0.9 0.1 1.3 0.5 -0.4 -1.2
Arm fat percentage (left) 1.3 5.3 12.0 -3.5 -1.5 -2.1 -2.0 -1.3 -2.0 -1.9 0.5 -2.8 -3.1 -2.6 -3.3 -1.2 -3.2 -2.8 -1.6 -1.3 -2.7 -1.6 1.7 -1.2 -2.2 -3.5
Average weekly red wine intake 0.2 0.3 1.8 -0.3 0.2 0.8 0.2 0.3 0.5 -0.3 0.7 0.5 0.4 0.3 0.3 -0.5 0.4 0.2 0.4 1.1 0.2 0.0 0.2 0.0 0.5 1.3
Handedness (chirality/laterality): Left-handed 1.3 1.5 5.4 -1.3 -1.0 -1.9 -1.0 -1.1 -1.3 0.1 -0.4 -1.4 -2.3 -1.1 -0.7 -0.9 -1.8 -1.1 -1.3 -1.8 -1.2 -0.7 0.8 -1.0 -0.6 -1.3
Mood swings 0.5 1.0 6.2 -0.1 -0.1 -1.2 -0.3 -0.3 -0.1 0.9 2.5 -1.3 -1.0 -0.6 -1.3 -1.0 -1.0 -0.5 -0.9 -1.2 -0.7 -0.9 -1.7 -0.1 -0.4 -0.3
Loneliness, isolation 0.3 0.5 1.6 -0.3 0.8 -0.9 0.7 0.4 0.8 1.3 0.8 -1.1 -0.8 0.4 -0.6 0.1 -0.6 -0.2 -0.4 -0.1 -0.3 -1.3 0.2 0.6 -0.8 0.5
Long-standing illness, disability or infirmity 0.3 0.4 1.6 0.1 -0.0 -0.4 -0.0 -0.1 -0.5 0.6 1.2 -0.7 -1.0 -0.6 -0.9 -0.4 -0.4 -0.1 -0.6 -0.8 -0.4 -1.3 -1.1 0.1 -0.5 0.4
Ever had bowel cancer screening 0.4 0.5 2.3 0.1 -0.6 0.2 -0.5 -0.5 -0.4 -1.3 0.1 0.2 -0.1 -1.0 1.5 -0.0 -0.3 -0.3 -0.4 -0.7 -0.4 -0.8 0.9 -0.5 -1.4 -0.0
Diabetes diagnosed by doctor 0.7 1.1 3.7 -1.6 -0.6 0.3 -0.7 -0.7 -1.1 -1.3 1.6 -0.1 -0.4 -1.9 -0.5 -0.4 -1.1 -1.5 -1.7 -1.0 -1.7 0.1 0.1 -0.7 -0.7 -0.6
Ever had stillbirth, spontaneous miscarriage or termination 1.0 1.1 2.3 -0.2 -1.5 -1.0 -1.4 -1.2 -0.3 -0.1 -0.5 -1.0 -1.4 -1.3 0.6 -0.5 -1.5 -1.2 -1.5 -1.2 -1.4 -0.8 -0.6 -1.4 -0.8 -0.3
Friendships satisfaction 0.9 1.1 4.8 1.0 0.2 1.9 0.5 0.3 0.4 0.5 -0.3 2.2 1.2 0.5 0.3 0.3 1.6 0.9 -0.4 0.8 0.8 2.0 -0.8 0.0 1.0 1.9
Qualifications: nursing, teaching 1.0 1.5 3.3 0.6 1.4 1.2 1.6 1.3 0.7 0.5 -1.3 0.9 1.4 0.8 0.9 1.0 1.4 1.2 1.6 1.8 1.4 0.4 1.1 1.4 1.1 1.7
Commuting to job workplace: Walk 3.2 3.4 6.8 1.6 2.6 1.1 2.5 2.5 2.2 2.5 1.0 1.4 1.8 2.1 -0.5 1.6 1.7 1.4 2.0 2.2 1.4 1.6 -1.2 2.4 2.1 1.3
Eye problems/disorders: Cataract 0.3 0.4 1.6 1.0 -0.1 0.6 0.3 0.4 -0.1 0.5 0.2 0.8 1.3 0.8 0.5 0.5 0.7 0.6 0.2 0.6 0.6 -0.5 0.3 0.2 0.8 1.0
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 4.8 0.4 -0.0 1.5 0.2 0.4 -0.6 -0.9 -2.2 1.4 1.2 0.0 -0.8 -0.9 0.7 -0.2 -0.7 -0.1 0.0 0.7 1.2 0.3 0.4 0.3
Medication for cholesterol 0.5 0.7 4.7 0.5 0.4 -0.3 0.4 0.6 0.3 -0.3 -0.7 -0.0 0.3 1.0 2.2 1.7 0.8 1.1 1.2 0.5 1.2 -0.5 -0.6 0.7 0.6 -0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.1 4.7 -0.3 -0.9 2.2 -0.6 -0.8 0.2 -0.6 1.7 2.1 1.1 -0.8 -0.1 -0.7 0.6 -0.5 0.1 1.1 -0.5 1.9 -0.2 -0.7 1.3 0.4
Back pain experienced in last month 0.5 0.7 2.8 -0.7 -0.9 -0.2 -0.8 -0.5 -0.3 -1.1 0.5 -0.6 -0.5 -1.4 -1.7 -1.0 -0.9 -1.0 -0.5 -0.3 -1.0 -1.3 0.9 -0.5 -0.6 -0.7
Mineral and other dietary supplements 4.5 6.0 10.4 2.8 2.5 1.5 2.8 2.4 3.2 3.0 1.6 1.8 2.3 2.3 3.0 2.8 2.6 2.2 3.0 2.2 2.2 0.6 -2.6 2.4 2.6 2.2
Breast cancer (self-reported) 6.3 7.5 14.4 -3.3 -2.7 -1.9 -2.9 -2.4 -3.3 -3.0 -1.4 -2.5 -2.8 -3.8 -1.6 -2.3 -3.4 -3.2 -1.9 -2.1 -3.1 -1.2 2.1 -2.3 -3.8 -3.8
Asthma (self-reported) 1.3 2.6 5.0 2.2 1.9 1.1 2.1 1.9 1.6 1.6 -0.2 1.2 2.0 1.7 1.0 1.1 2.2 1.9 1.2 1.3 2.0 0.9 -1.8 1.8 1.0 1.2
Osteoporosis (self-reported) 0.5 0.7 2.3 0.5 0.0 1.5 0.1 -0.3 0.5 -0.7 1.4 1.2 1.2 -0.5 1.1 0.2 0.9 0.3 0.3 0.2 0.3 1.5 -1.4 -0.1 0.4 0.5
Osteoarthritis (self-reported) 0.6 0.8 2.4 -1.3 -1.1 -1.1 -1.0 -0.8 0.0 -1.0 -0.0 -1.1 -1.3 -0.4 -1.6 -1.3 -0.8 -0.1 -0.2 -0.7 -0.2 -0.0 1.1 -0.8 -1.4 -0.6
Medication: Aspirin 0.8 1.0 6.2 -1.2 -0.5 0.5 -0.7 -0.6 0.2 -0.6 0.4 -0.4 -0.7 -0.6 -2.5 -1.8 -0.8 -1.5 -0.3 0.7 -1.5 -0.8 0.7 -0.6 -1.1 -1.2
Medication: Gliclazide 0.7 0.8 4.1 0.7 0.2 1.6 0.4 0.1 0.7 -1.5 -0.0 1.2 1.2 -1.0 1.3 2.0 0.7 0.1 0.7 0.5 0.1 0.7 0.9 -0.1 -0.1 -0.1
Illnesses of father: None of the above (group 1) 1.4 1.8 5.6 1.5 0.8 1.7 1.1 0.2 1.1 -0.7 1.9 1.4 2.4 0.7 0.5 0.5 1.9 1.2 1.9 2.3 1.2 -0.4 -1.0 0.6 1.3 1.1
Smoking status: Current 0.5 0.7 2.8 -0.9 -1.1 -1.5 -0.9 -0.8 0.0 1.0 1.7 -1.5 -0.7 0.0 0.9 0.2 -1.2 -0.3 0.8 0.2 -0.5 -0.1 0.2 -0.8 -0.5 -0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.3 1.0 -0.1 -0.7 0.5 -0.9 -1.0 -0.9 -0.4 0.0 0.7 -0.1 -0.4 0.3 -0.6 -0.1 -0.6 -0.8 -0.7 -0.6 -0.1 -0.1 -1.0 -0.4 0.8
Whole body water mass 0.2 1.3 5.3 -1.4 0.5 -1.5 0.2 0.5 -0.0 -0.0 -0.3 -1.5 -1.5 -0.8 -2.3 -1.4 -1.7 -0.8 -1.3 -1.7 -0.9 -0.4 1.1 0.2 -1.1 -1.2
Leg predicted mass (right) 0.2 0.9 3.0 -1.6 0.4 -0.9 0.1 0.7 -0.2 -0.3 0.1 -1.0 -1.2 -0.7 -1.7 -1.0 -1.4 -0.8 -0.9 -1.0 -0.9 0.0 1.3 0.4 -0.5 -1.2
Arm fat mass (left) 1.4 5.6 14.4 -3.5 -1.1 -2.5 -1.8 -1.1 -1.8 -1.4 0.3 -3.1 -3.2 -2.5 -3.8 -1.6 -3.5 -2.7 -1.8 -1.8 -2.7 -1.7 1.7 -1.1 -2.4 -3.3
Number of self-reported non-cancer illnesses 0.1 0.2 1.0 0.5 -0.3 1.0 -0.1 -0.5 0.3 0.3 0.8 0.5 0.5 -0.1 -0.0 -0.5 0.2 -0.2 -0.1 -0.4 -0.4 -0.2 -0.5 -0.4 -0.9 0.8
Average weekly champagne plus white wine intake 0.9 1.2 5.2 1.5 0.7 -0.0 0.9 1.1 1.3 0.9 -0.4 0.0 0.3 0.9 1.3 1.1 1.2 1.3 1.1 0.7 1.3 -2.3 -0.7 0.9 0.7 1.7
Miserableness 1.5 2.6 7.8 -1.6 -1.1 -1.9 -1.3 -1.1 -1.1 -0.3 1.0 -2.4 -1.7 -1.4 -1.8 -2.0 -2.0 -1.3 -2.0 -2.8 -1.6 -1.4 0.1 -1.0 -2.2 -1.1
Guilty feelings 0.3 0.4 1.4 -0.7 0.3 1.1 0.4 0.1 -0.8 0.2 0.8 1.0 0.4 -0.6 0.1 -0.1 0.3 -0.5 0.6 1.2 -0.5 0.9 -0.4 0.1 0.1 0.5
Wears glasses or contact lenses 0.5 0.6 3.1 0.5 0.3 0.7 0.4 0.1 1.0 0.8 0.3 0.1 0.4 0.1 1.7 1.7 0.3 0.2 1.2 0.5 0.1 0.4 1.1 0.0 -1.1 0.7
Ever taken oral contraceptive pill 0.5 0.6 2.3 -0.2 0.1 -1.2 -0.2 -0.5 -0.6 1.1 1.3 -0.8 -1.1 -0.1 0.9 1.0 -0.5 0.2 1.5 0.2 -0.0 0.0 -1.1 0.1 -0.1 0.2
Hearing aid user 1.7 1.9 5.7 -0.7 -1.9 0.9 -1.7 -1.8 -1.9 -1.8 -0.2 0.3 0.0 -1.5 -1.6 -2.4 -0.7 -1.3 -1.6 -0.4 -1.4 -0.3 1.5 -2.3 -0.9 0.2
Mother’s age at death 0.3 0.4 1.4 -0.0 0.1 1.1 0.5 0.2 -0.4 -1.2 0.1 1.2 1.0 -0.5 0.6 0.3 0.6 -0.1 0.4 1.2 -0.0 0.3 0.5 0.0 0.8 0.2
Financial situation satisfaction 1.2 1.4 9.2 0.2 -1.6 1.5 -1.1 -1.5 -0.4 -0.3 1.4 0.7 0.9 -0.4 0.7 -0.9 0.3 -0.5 1.7 3.0 -0.7 -0.6 -0.3 -1.5 1.5 1.4
Tinnitus: Yes, now most or all of the time 0.4 0.4 2.2 0.2 0.7 0.4 0.8 0.6 0.5 0.6 1.3 0.5 0.5 0.5 0.3 -0.0 0.6 0.4 0.3 1.0 0.4 -0.1 -0.9 0.7 1.5 0.5
Commuting to job workplace: Public transport 3.1 3.7 10.0 2.4 2.2 1.7 2.4 1.8 3.2 1.7 -1.4 1.7 1.8 2.0 1.3 2.6 2.3 2.1 2.2 1.7 2.1 0.6 0.9 1.6 1.2 1.5
Eye problems/disorders: Glaucoma 1.8 2.1 8.4 -2.0 -1.6 1.3 -1.5 -1.4 -1.2 -2.0 -1.3 0.8 -0.0 -2.0 0.5 -1.2 -0.7 -1.9 -0.2 -0.1 -1.7 1.2 2.9 -1.4 -1.4 -1.3
Medication: Blood pressure 0.4 0.8 5.1 -0.7 -0.5 0.0 -0.5 -0.4 0.0 0.6 1.8 -0.6 -0.2 -0.5 -1.6 -2.3 -0.7 -0.7 -0.2 0.9 -0.9 -0.8 -0.9 -0.5 0.2 0.5
Pain type(s) experienced in last month: Hip pain 2.7 3.4 7.9 -2.3 -1.6 -1.4 -1.8 -1.3 -2.4 -1.7 0.8 -1.8 -2.8 -2.8 -1.6 -1.9 -2.2 -2.1 -1.3 -1.5 -2.2 -1.6 0.2 -1.2 -2.2 -1.6
Supplements: Fish oil (including cod liver oil) 4.0 5.3 11.6 -2.8 -2.0 -1.7 -2.3 -2.0 -2.8 -2.9 -0.3 -2.2 -2.6 -2.5 -3.4 -2.9 -2.7 -2.2 -2.0 -1.7 -2.2 -2.0 1.6 -1.7 -2.4 -2.3
High cholesterol (Self-reported) 0.8 1.4 7.1 -1.2 -0.6 0.1 -0.9 -0.9 -0.8 0.0 -1.4 -0.4 -1.4 -0.7 -0.5 -1.6 -1.2 -1.4 -1.2 -1.7 -1.6 -0.3 1.5 -1.0 -2.7 -0.3
Medication: Bendroflumethiazide 0.5 0.8 4.0 0.8 0.9 0.4 0.7 0.5 1.8 0.8 -0.3 -0.2 0.7 0.7 0.4 2.0 0.5 0.1 1.7 1.1 0.2 -0.1 -1.0 0.7 0.2 -0.7
Medication: Paracetamol 0.9 1.4 5.6 -0.3 -1.4 1.0 -1.2 -1.5 -0.4 -0.9 2.4 0.3 0.2 -1.1 -0.3 -1.2 0.1 -0.6 0.7 1.8 -0.8 -1.5 -1.0 -1.6 0.8 2.0
Medication: Lisinopril 0.8 1.1 5.8 -1.3 -0.5 -0.9 -0.4 -0.7 -0.4 -0.1 0.2 -1.2 -1.1 -1.1 -0.5 -1.1 -1.6 -1.2 -1.3 -0.4 -1.3 -2.4 0.8 -0.6 -1.1 -0.5
Medication: Atorvastatin 0.9 1.1 2.4 1.1 1.6 0.2 1.2 1.4 0.8 0.9 0.5 -0.3 0.8 1.5 -0.4 0.3 1.1 1.3 1.4 0.6 1.3 -1.1 -1.0 1.4 0.6 0.7
Illnesses of father: High blood pressure 0.3 0.3 1.3 -0.7 0.6 -0.6 0.5 0.7 0.6 0.5 -0.9 -0.6 -0.2 0.9 0.3 0.3 -0.3 0.0 0.5 0.4 0.2 0.5 1.1 0.6 0.2 -0.7
Alcohol drinker status: Never 0.2 0.3 1.1 0.5 -0.4 0.2 -0.4 -0.3 0.8 -1.0 -0.7 0.3 0.3 -0.4 0.8 0.5 0.2 0.1 0.3 -0.8 0.2 0.6 0.3 -0.1 -0.5 -0.9
Ever smoked 2.1 3.6 12.3 1.2 2.4 -1.1 2.0 2.3 2.2 3.5 1.7 -0.9 -0.3 2.3 1.8 2.2 0.6 2.0 2.5 1.2 1.8 -0.2 -2.5 2.5 1.1 1.6
Basal metabolic rate 0.3 1.8 6.7 -1.8 0.2 -1.6 -0.2 0.2 -0.4 -0.3 -0.1 -1.7 -1.8 -1.3 -2.6 -1.5 -2.0 -1.3 -1.5 -1.8 -1.4 -0.5 1.3 -0.0 -1.2 -1.6
Leg fat percentage (left) 1.9 6.7 14.8 -3.8 -2.1 -2.5 -2.5 -1.8 -2.2 -1.5 1.1 -3.2 -3.6 -2.9 -3.1 -1.6 -3.9 -3.2 -1.9 -1.3 -3.3 -2.5 1.5 -1.6 -2.3 -3.3
Arm fat-free mass (left) 0.6 2.9 8.2 -2.1 -0.0 -2.4 -0.4 -0.1 -0.4 -0.1 -0.6 -2.5 -2.3 -1.5 -2.9 -1.9 -2.7 -1.6 -1.6 -2.1 -1.7 -1.1 1.4 -0.3 -1.9 -2.0
Number of operations (self-reported) 0.1 0.2 1.5 0.3 -0.2 0.5 -0.2 -0.0 1.2 0.2 0.4 0.4 0.5 0.4 0.3 0.4 0.2 0.0 -0.2 -0.7 0.0 0.7 -0.5 0.0 -0.5 -0.3
Average weekly beer plus cider intake 1.0 1.4 3.0 -0.9 -1.1 -0.6 -1.3 -1.1 -1.6 -0.9 -0.6 -0.8 -0.9 -1.2 -1.7 -1.6 -1.1 -1.3 -1.4 -1.7 -1.3 0.2 0.5 -1.0 -0.9 -1.7
Irritability 1.1 1.9 5.1 -1.3 -2.3 0.3 -2.0 -1.6 -1.8 -1.5 0.3 -0.4 -0.4 -1.5 -2.3 -2.2 -1.0 -1.5 -0.4 -0.1 -1.5 -0.9 1.1 -1.7 -1.2 -0.8
Risk taking 1.6 2.3 4.1 1.5 1.8 0.6 2.0 1.8 1.2 1.5 0.8 0.9 1.6 1.7 0.0 1.5 1.7 2.0 0.6 1.8 2.0 1.3 -0.9 1.8 1.9 1.9
Ever had prostate specific antigen (PSA) test 0.4 0.4 2.2 1.0 0.5 0.2 0.6 0.5 0.9 0.1 1.5 0.6 0.3 0.0 -0.5 0.2 0.3 0.3 -0.2 -0.0 0.3 -0.9 -1.4 0.7 0.0 0.6
Fractured/broken bones in last 5 years 1.0 1.3 3.8 -0.2 1.8 0.9 1.8 1.7 0.5 0.1 2.0 0.8 0.7 0.6 -0.8 1.2 0.8 0.5 -0.3 0.9 0.7 -0.2 -1.7 1.8 1.6 1.2
Age started oral contraceptive pill 0.8 1.1 4.0 1.3 2.0 0.3 1.6 1.5 1.0 1.6 -1.1 1.2 0.4 0.9 -0.1 0.3 0.9 0.5 0.5 0.3 0.6 1.4 -0.3 1.3 0.8 0.5
Diastolic blood pressure, automated reading 0.9 2.7 8.0 -2.2 -0.7 -2.8 -1.2 -0.5 -1.3 -0.8 1.6 -2.8 -2.4 -1.9 -1.4 -1.5 -2.3 -1.1 -1.6 -1.9 -1.2 -1.6 -0.2 -0.5 -1.4 -1.4
Ever depressed for a whole week 0.3 0.4 4.2 0.2 -0.1 -0.3 0.2 -0.3 0.3 0.2 1.3 -0.5 0.7 0.1 -0.1 0.5 0.1 0.5 0.1 -0.2 0.5 -1.2 -2.0 -0.3 0.0 0.4
Unable to work because of sickness or disability 0.5 0.6 2.7 -0.6 -0.2 -1.0 -0.1 -0.2 -0.8 -1.1 0.8 -1.0 -1.1 -0.8 -0.8 -1.1 -0.5 -0.0 -0.7 -1.6 -0.1 -0.7 0.0 -0.2 -1.1 0.3
Commuting to job workplace: Cycle 0.8 0.9 3.8 1.0 0.8 1.5 0.8 0.6 -0.0 0.8 -2.0 1.5 1.4 0.9 0.5 0.0 1.3 0.5 -0.1 -0.7 0.7 1.6 0.7 0.2 0.1 0.5
Myopia 0.5 0.7 4.3 1.1 0.5 0.4 0.7 -0.0 0.1 -0.3 0.7 0.7 0.9 0.4 1.5 2.1 1.1 1.1 -0.4 -0.4 1.1 0.7 -0.3 0.1 -0.0 1.0
Vascular/heart problems diagnosed by doctor 0.1 0.4 1.6 0.5 0.1 0.5 0.5 0.2 -0.6 -0.8 -0.7 0.7 1.2 0.2 0.3 1.3 0.7 0.4 0.4 0.5 0.7 0.1 0.9 0.2 0.8 -0.4
Cholesterol lowering medication 0.6 0.9 2.9 -1.0 -0.1 -0.3 -0.5 -0.4 0.0 1.1 1.0 -0.3 -1.1 -0.8 -1.3 -1.2 -1.3 -1.2 -1.7 -1.6 -1.5 0.6 -0.5 -0.1 -0.8 -0.1
Medication: Omeprazole (e.g. Zanprol) 1.0 1.2 3.5 -1.1 -1.2 -0.3 -1.3 -1.1 -0.9 -1.6 0.9 -0.5 -0.7 -0.9 -1.6 -1.1 -1.0 -1.1 -1.9 -1.0 -1.1 -1.6 0.0 -1.2 -0.3 -0.2
Pain experienced in last month 0.9 1.5 3.3 1.4 1.0 1.0 1.1 0.5 1.7 1.2 -0.0 1.2 1.1 1.4 0.8 1.4 1.6 1.7 0.7 0.7 1.7 1.4 -1.0 0.5 1.8 1.5
Supplements: Calcium 0.6 0.6 2.9 -0.8 -0.8 1.0 -0.5 -0.8 -1.4 -1.7 -0.4 0.6 0.5 -0.9 -0.1 -0.5 0.0 -0.7 -0.4 0.0 -0.5 0.3 1.3 -0.9 -1.0 -0.7
Basal cell carcinoma (self-reported) 0.4 0.5 1.3 -0.7 -0.8 -0.5 -0.8 -0.9 -0.3 -0.1 0.9 -1.1 -1.1 -0.9 0.2 -0.9 -0.8 -0.7 0.5 -0.0 -0.8 -0.5 0.0 -0.8 -0.9 -0.3
Heart attack/myocardial infarction (self-reported) 0.5 0.7 2.3 -0.9 -1.5 0.4 -1.5 -1.2 0.3 -0.0 1.3 0.3 -1.0 -1.1 0.1 -0.5 -0.7 -1.1 -0.2 0.3 -1.2 0.1 0.1 -1.2 -0.1 -0.1
Deep venous thrombosis (DVT) (self-reported) 1.0 1.3 4.2 1.7 -0.1 1.7 0.2 -0.3 0.5 0.7 1.4 1.9 1.4 0.9 -0.2 0.6 1.5 0.7 0.1 0.8 0.6 1.2 -1.3 -0.4 1.6 2.0
Heart disease (siblings) 2.3 2.8 6.1 -2.3 -1.6 -1.2 -1.8 -1.2 -2.2 0.0 0.4 -1.7 -1.9 -2.0 -1.0 -1.8 -2.5 -2.5 -1.6 -0.7 -2.4 -1.3 0.5 -1.4 -1.5 -1.6
Alcohol drinker status: Previous 0.7 0.8 4.6 -0.9 -0.4 0.1 -0.5 -0.3 -0.5 -1.3 -1.2 0.6 -0.5 -0.9 -1.1 -0.7 -0.5 -0.8 -1.1 -1.1 -0.7 2.1 1.0 -0.3 -0.5 -0.9
Pack years of smoking 0.5 0.8 3.1 -0.4 -1.2 0.0 -1.0 -1.1 -0.4 -0.4 1.5 -0.4 -0.6 -0.9 -0.6 -1.8 -0.7 -0.9 0.8 0.8 -1.1 -1.1 -0.4 -1.0 -0.3 -0.5
Impedance of whole body 0.2 1.3 6.3 1.1 -1.0 1.7 -0.7 -1.1 -0.1 -0.1 -0.3 1.9 1.5 0.5 2.5 1.6 1.3 0.3 0.6 0.7 0.4 1.6 -0.5 -0.9 1.0 0.1
Leg fat mass (left) 1.6 6.3 14.6 -3.8 -1.5 -2.5 -2.0 -1.2 -1.9 -1.7 0.8 -3.1 -3.4 -2.8 -3.3 -1.7 -3.8 -3.0 -2.1 -1.7 -3.1 -1.9 1.7 -1.1 -2.3 -3.4
Arm predicted mass (left) 0.4 2.2 6.5 -1.8 0.2 -2.1 -0.2 0.0 -0.3 -0.0 -0.4 -2.1 -2.0 -1.2 -2.5 -1.7 -2.4 -1.4 -1.6 -1.9 -1.5 -1.0 1.2 -0.1 -1.5 -1.6