Hub : Genes

RALB

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells EBV-transformed lymphocytes	0.4100	0.0770	3.0e-07	0.234	NA	0.337	NA	0.289	3.4e-08	NA	9.3e-12	NA	5.0e-10
2	GTEx	Esophagus Muscularis	0.1360	0.0520	2.5e-05	0.032	NA	0.050	NA	0.030	4.8e-03	NA	5.6e-04	NA	5.7e-03
3	GTEx	Heart Left Ventricle	0.1334	0.0597	1.4e-03	0.094	NA	0.031	NA	0.070	1.1e-05	NA	9.2e-03	NA	1.4e-04
4	GTEx	Muscle Skeletal	0.1322	0.0369	1.6e-08	0.118	NA	0.134	NA	0.139	1.2e-11	NA	4.5e-13	NA	1.6e-13
5	GTEx	Nerve Tibial	0.1763	0.0457	1.2e-06	0.157	NA	0.135	NA	0.143	3.2e-11	NA	8.8e-10	NA	2.6e-10
6	GTEx	Skin Sun Exposed Lower leg	0.0740	0.0300	1.0e-03	0.036	NA	0.029	NA	0.030	5.2e-04	NA	1.8e-03	NA	1.5e-03
7	GTEx	Testis	0.4370	0.0660	4.6e-14	0.442	NA	0.415	NA	0.442	1.9e-21	NA	6.6e-20	NA	1.7e-21
8	GTEx	Thyroid	0.0730	0.0310	1.6e-03	0.041	NA	0.017	NA	0.027	4.0e-04	NA	1.7e-02	NA	3.4e-03
9	METSIM	Adipose	0.0784	0.0248	4.6e-06	0.042	0.035	0.023	0.035	0.026	6.0e-07	5.2e-06	1.7e-04	5.0e-06	8.3e-05
10	NTR	Blood	0.0361	0.0109	2.5e-06	0.033	0.021	0.029	0.025	0.026	5.9e-11	1.2e-07	6.7e-10	1.5e-08	4.8e-09
11	ROSMAP	Brain Pre-frontal Cortex	0.1703	0.0367	1.0e-15	0.087	0.142	0.111	0.143	0.114	2.9e-11	9.0e-18	4.1e-14	6.7e-18	1.8e-14
12	YFS	Blood	0.1149	0.0197	0.0e+00	0.162	0.134	0.161	0.156	0.162	1.3e-50	1.5e-41	2.7e-50	9.7e-49	1.8e-50
13	TCGA	Breast Invasive Carcinoma	0.0300	0.0144	5.6e-06	0.031	0.031	0.037	NA	0.036	3.7e-07	3.9e-07	3.2e-08	NA	4.8e-08
14	TCGA	Brain Lower Grade Glioma	0.0270	0.0139	3.8e-04	0.036	0.025	0.034	NA	0.033	5.4e-05	7.2e-04	8.8e-05	NA	1.2e-04
15	TCGA	Liver Hepatocellular Carcinoma	0.0780	0.0410	3.2e-03	0.061	0.062	0.071	NA	0.069	7.8e-04	7.4e-04	3.1e-04	NA	3.8e-04
16	TCGA	Lung Squamous Cell Carcinoma	0.0204	0.0126	6.8e-03	0.019	0.012	0.004	NA	0.009	2.9e-03	1.5e-02	1.0e-01	NA	2.7e-02
17	TCGA	Prostate Adenocarcinoma	0.1993	0.0657	0.0e+00	0.213	0.194	0.195	NA	0.216	5.7e-22	6.8e-20	4.8e-20	NA	3.1e-22

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	2.3	3.7	8.4	-0.7	-1.8	-1.6	-1.8	-1.8	-1.9	2.1	-2.8	-1.3	1.1	-2.4	1.8	1.7	-2.9	-1.6	2.2	1.9
Bipolar Disorder or Schizophrenia	0.4	1.0	6.1	0.7	-0.6	0.0	-0.9	-0.5	-0.4	0.9	-2.2	-0.2	0.2	-0.6	0.5	0.6	-2.5	-0.0	1.3	0.5
Depressed Affect (Nagel 2018)	0.7	1.5	3.1	-1.6	-1.1	-1.4	-0.8	-1.3	-1.3	1.0	-0.2	-1.6	1.5	-1.8	1.2	1.0	-0.2	-1.0	1.1	1.1
Depression (Nagel 2018)	0.6	0.9	2.5	-1.2	-0.6	-1.4	-0.8	-1.0	-0.9	0.8	0.0	-1.1	1.0	-1.6	1.0	0.1	0.1	-0.8	0.9	1.0
Intelligence (Savage-Jansen 2018)	1.5	4.8	7.8	-2.3	-2.1	-2.6	-2.1	-2.2	-2.5	2.5	-2.4	-1.3	1.5	-1.5	2.1	1.7	-2.8	-2.2	2.5	2.1
Neuroticism (Nagel 2018)	1.7	4.0	6.5	-2.5	-1.7	-2.2	-1.5	-2.3	-2.4	2.0	-1.1	-2.2	2.4	-2.0	2.2	1.7	-0.7	-1.9	2.0	2.1
Schizophrenia (2018)	0.4	0.8	1.9	1.4	0.6	1.3	0.2	0.8	1.0	-0.6	-0.6	0.8	-0.7	1.2	-0.8	-0.8	-0.8	1.2	-0.1	-0.8
Schizophrenia vs Biploar Disorder	0.4	0.6	1.2	0.2	0.5	0.9	0.5	0.8	1.0	-0.9	0.8	-0.8	-0.0	1.1	-0.7	-0.8	0.7	0.9	-0.6	-0.7
Worry (Nagel 2018)	1.7	3.7	7.5	-2.7	-1.5	-2.1	-1.5	-2.2	-2.5	2.1	-1.7	-1.4	2.0	-1.4	2.0	1.8	-0.9	-1.3	2.2	2.1
Alzheimer’s Disease (in mother)	0.3	0.4	0.7	-0.6	-0.2	-0.8	-0.7	-0.6	-0.7	0.8	-0.8	-0.7	0.5	0.1	0.5	0.8	-0.6	-0.7	0.6	0.6
Alzheimer’s Disease (in father)	0.8	0.9	2.6	-1.6	-0.3	-1.1	-0.4	-1.1	-1.2	1.0	-0.5	0.3	1.3	-0.7	1.0	0.9	0.1	-1.3	0.7	1.1
Alzheimer’s Disease (including proxy)	0.2	0.3	1.4	-0.7	1.0	0.4	0.2	0.2	-0.2	-0.3	0.5	0.5	-0.1	0.7	-0.2	0.1	1.2	-0.4	-0.6	-0.2
Crohns Disease (2017)	0.3	0.6	1.6	0.1	0.8	1.2	0.5	0.7	-0.1	-0.8	0.8	0.9	-0.4	1.2	-0.5	-0.6	1.1	0.2	-0.8	-0.6
Irritable Bowel Disease (IBD)	0.1	0.2	1.3	-1.1	-0.3	0.1	-0.4	-0.3	-0.8	0.1	-0.1	0.2	0.1	-0.1	0.4	0.7	-0.2	-0.6	0.1	0.3
Ulcerative Colitis (UC)	0.6	1.0	2.8	-1.7	-1.0	-1.0	-1.1	-1.0	-1.1	0.8	-0.6	-0.5	0.7	-0.9	1.0	1.4	-1.2	-1.2	0.6	0.9
Major Depression (MDD)	1.1	1.4	5.9	1.1	1.3	1.2	1.5	1.2	1.2	-0.9	0.3	0.8	-0.7	2.4	-1.1	-1.2	0.5	1.2	-0.8	-1.1
Reaction Time	2.4	4.6	9.9	3.1	2.3	1.8	2.1	2.3	2.3	-2.1	1.1	1.8	-2.6	2.1	-2.4	-1.7	1.0	2.1	-2.0	-2.4
Verbal and Numeric Reasoning (VNR)	0.8	1.8	3.1	-1.8	-1.2	-1.6	-0.9	-1.4	-1.8	1.4	-1.2	-0.9	1.2	-0.8	1.4	1.2	-1.6	-1.6	1.5	1.3
Breast Cancer	8.2	19.7	39.2	-6.3	-4.5	-4.6	-4.4	-4.8	-4.6	4.7	-3.7	-4.8	3.7	-2.7	4.7	4.0	-2.9	-4.8	4.3	4.8
Ovarian Cancer	0.4	0.5	2.0	-0.0	0.5	0.5	0.5	0.7	1.2	-0.8	1.0	0.8	-0.7	0.3	-0.7	-0.6	0.3	1.4	-0.5	-0.7
Prostate Cancer	1.1	1.6	3.9	1.3	1.5	1.4	1.9	1.0	0.7	-1.3	1.5	1.4	-0.3	1.2	-0.9	-0.8	2.0	0.5	-1.4	-1.0
Age at First Birth	0.3	0.4	1.6	-0.8	-0.5	-0.0	-0.2	-0.8	-0.3	0.6	-0.5	-0.2	1.3	0.2	0.8	0.5	-0.1	-0.8	0.6	0.9
Bipolar Disorder (2011)	1.5	1.5	7.6	-0.2	-0.6	-0.5	-0.6	-0.8	-0.8	1.4	-2.8	0.9	-0.3	-0.7	0.6	1.0	-2.7	-0.6	1.5	0.8
Body Mass Index (BMI) (2010)	1.3	1.8	3.5	-1.0	-1.4	-1.6	-1.6	-1.4	-1.4	1.5	-1.3	-1.2	1.3	-1.0	1.3	1.3	-1.4	-0.7	1.9	1.4
Coronary Artery Disease (CAD)	0.3	0.4	1.0	-0.8	-0.4	-0.2	-1.0	-0.8	-0.5	0.2	-0.2	-0.8	0.7	-0.2	0.7	0.9	0.2	-0.6	0.5	0.8
Crohns Disease (2012)	0.1	0.2	0.9	-0.1	0.7	0.8	0.1	0.2	-0.3	-0.3	0.3	-0.2	-0.0	1.0	-0.1	-0.2	0.6	-0.2	-0.3	-0.1
Mean Putamen Volume	0.2	0.3	2.1	-0.6	0.1	-0.9	0.3	-0.4	-0.4	0.4	-0.1	1.5	-0.2	0.0	0.3	0.5	-0.3	0.1	0.3	0.3
Fasting Glucose	0.1	0.2	0.7	0.7	-0.8	0.2	-0.1	0.0	0.1	-0.1	-0.4	0.2	0.1	-0.5	-0.0	0.1	-0.9	0.5	0.2	-0.0
HbA1C	0.6	0.7	1.8	-0.8	-0.6	-0.6	-0.9	-0.7	-0.8	1.0	-1.2	-0.3	0.8	0.1	0.8	1.0	-1.1	-0.1	1.3	0.8
HDL Cholesterol	0.1	0.1	0.4	-0.4	-0.2	-0.4	0.1	0.2	0.2	-0.2	0.5	0.2	-0.2	-0.7	-0.2	-0.3	0.0	0.3	-0.3	-0.3
LDL Cholesterol	0.4	0.6	3.2	-1.1	0.2	-0.7	-0.5	-0.8	-0.9	0.6	-0.1	1.8	0.9	-0.5	0.5	0.4	0.6	-0.9	0.2	0.6
Lupus	0.2	0.2	0.5	0.2	-0.6	-0.5	-0.1	0.3	0.5	-0.4	0.7	0.7	-0.4	-0.7	-0.3	-0.5	-0.4	0.7	-0.0	-0.5
Neuroticism (2016)	0.2	0.3	1.8	-0.4	0.5	0.3	0.5	-0.1	0.1	-0.6	1.2	0.4	0.3	-0.9	0.1	-0.3	1.3	-0.4	-0.3	-0.0
Primary Biliary Cirrhosis	0.2	0.3	0.9	-1.0	-0.4	-0.1	-0.8	-0.4	-0.5	0.4	-0.2	-0.5	0.7	-0.4	0.6	0.3	0.3	-0.5	0.3	0.5
Rheumatoid Arthritis	0.8	1.1	2.2	-1.3	-0.9	-0.8	-1.1	-1.0	-1.1	1.2	-1.5	-0.9	0.6	-0.2	1.0	0.9	-1.4	-0.5	1.3	1.1
Schizophrenia (2014)	0.4	0.9	3.1	1.8	0.9	1.3	0.6	1.0	1.1	-0.7	-0.4	0.3	-0.7	1.3	-0.9	-1.1	-0.8	0.9	-0.4	-0.9
Triglycerides	0.7	1.2	1.7	1.2	1.2	1.3	1.1	1.1	0.9	-1.1	0.7	1.2	-1.0	1.2	-1.3	-1.1	0.9	1.0	-1.0	-1.1
Type 2 Diabetes (T2D) (2012)	1.7	1.9	3.7	1.4	1.5	1.8	1.7	1.3	1.4	-1.5	1.2	0.6	-1.3	1.9	-1.3	-1.4	1.0	1.2	-1.4	-1.3
Ulcerative Colitis	0.2	0.2	1.0	-0.8	-0.3	-0.1	-0.2	-0.4	-0.2	0.4	-0.6	-0.1	-0.1	-0.7	0.3	0.8	-1.0	-0.0	0.4	0.3
Blood Eosinophil Count	0.3	2.1	3.8	1.9	1.3	1.9	1.4	1.8	1.4	-1.4	0.2	2.0	-1.8	0.7	-1.5	-1.4	-0.4	1.4	-0.9	-1.7
Blood Platelet Count	20.6	238.4	282.2	14.5	16.6	14.7	16.7	16.3	16.0	-16.4	14.3	13.6	-14.6	15.8	-16.2	-14.4	13.8	15.0	-16.8	-16.2
Blood Red Count	0.2	2.2	7.8	2.8	0.5	1.4	0.8	1.3	1.7	-0.6	-1.3	1.2	-1.6	2.5	-1.3	-1.3	-1.7	1.5	-0.2	-1.2
Blood White Count	0.0	0.1	0.8	0.0	-0.7	-0.3	-0.3	-0.1	0.1	0.2	-0.2	0.4	0.4	-0.3	0.4	-0.1	-0.4	-0.9	0.0	0.2
Heel T-Score	0.1	0.7	3.1	0.9	0.1	0.8	-0.5	0.7	0.9	-0.4	-0.6	0.6	-1.4	0.3	-0.9	-0.9	-0.8	1.8	-0.1	-0.7
BMI	0.5	2.6	7.7	-0.7	-2.4	-1.3	-1.4	-1.4	-1.5	1.5	-1.5	-2.8	2.0	-0.6	1.5	1.5	-1.7	-1.5	1.7	1.3
Height	0.5	10.0	23.6	2.1	4.4	2.8	3.9	2.7	2.6	-2.7	2.1	4.9	-3.2	3.6	-2.9	-2.5	3.3	2.5	-3.3	-2.7
Waist Hip Ratio (WHR)	0.2	1.0	4.5	-2.1	-0.4	-1.1	-0.7	-1.1	-1.1	0.9	-0.2	0.1	0.9	-1.1	1.0	1.4	0.3	-1.4	0.1	1.1
Systolic Blood Pressure	0.3	1.6	5.5	-0.7	1.6	1.0	1.9	0.7	0.9	-1.2	2.1	0.6	-0.2	1.2	-0.7	-0.9	2.4	0.8	-1.6	-0.7
Smoking Status	1.5	3.5	6.7	-1.1	-2.4	-1.8	-2.1	-1.8	-1.8	1.8	-1.5	-1.7	1.6	-2.6	1.8	2.0	-1.7	-1.6	2.0	1.8
Allergy or Eczema	0.2	0.4	4.2	0.6	0.0	-0.4	0.2	0.2	0.2	0.3	-0.9	0.4	-0.9	-0.0	-0.1	0.4	-2.0	0.3	0.4	-0.2
Cardiovascular Disease	0.1	0.5	3.4	-0.9	-0.4	-0.4	-0.2	-0.6	-0.8	0.5	-0.1	-1.9	0.5	-0.3	0.7	0.6	0.1	-0.7	0.2	0.7
Hypothyroidism (self reported)	0.1	0.2	0.6	0.5	-0.2	0.1	0.7	0.4	0.7	-0.2	0.1	-0.7	-0.5	0.2	-0.2	-0.2	-0.3	0.3	-0.3	-0.4
Respiratory disease	0.7	1.6	3.8	-1.8	-1.4	-1.9	-1.2	-1.1	-1.2	1.1	-0.5	-1.0	1.0	-1.2	1.1	1.2	-0.8	-1.6	1.2	1.0
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.6	0.4	1.0	0.3	0.9	0.6	1.0	-0.5	0.4	-1.2	-0.9	1.2	-0.8	-0.4	0.4	1.1	-0.7	-0.6
Lung FEV1/FVC ratio	2.6	13.1	24.0	2.7	4.4	4.1	4.5	3.4	3.2	-3.8	3.7	1.9	-2.4	4.2	-3.3	-3.3	4.9	1.9	-4.7	-3.2
Lung FVC	0.6	3.0	13.1	-1.1	-2.3	-1.1	-2.3	-1.3	-1.1	1.4	-1.7	-0.0	0.9	-3.6	1.4	1.5	-2.6	-1.1	1.7	1.3
Neuroticism	1.0	2.4	4.1	-2.0	-1.4	-1.9	-1.1	-1.7	-1.8	1.6	-0.8	-1.2	1.9	-2.0	1.7	1.1	-0.4	-1.5	1.5	1.6
Chronotype (morning person)	0.1	0.3	1.2	0.5	-0.3	0.3	-0.2	0.5	0.2	-0.2	-0.2	-0.2	-1.1	1.1	-0.5	-0.6	-0.6	0.7	-0.2	-0.5
Hair Pigment	0.0	0.9	3.7	-0.4	-0.8	-1.1	-1.4	-0.8	-0.9	0.7	-0.2	-1.2	1.6	-0.4	0.9	0.3	-0.4	-1.9	-0.0	0.8
Tanning	0.1	1.2	2.5	1.6	0.9	1.2	0.8	1.3	1.4	-1.2	0.8	0.4	-1.5	1.0	-1.1	-1.2	0.5	1.0	-0.9	-1.3
Hand grip strength (left)	0.8	2.1	3.3	1.0	1.7	1.3	1.4	1.4	1.8	-1.5	1.3	1.6	-1.3	1.2	-1.7	-1.2	1.1	1.8	-1.6	-1.6
Number of treatments/medications taken	0.2	0.3	2.4	1.5	0.2	0.3	0.2	0.3	0.3	-0.3	0.1	0.5	-0.5	0.9	-0.4	-0.6	0.0	0.3	-0.3	-0.4
Average weekly spirits intake	1.4	1.8	3.3	1.0	1.8	1.4	1.8	1.3	0.9	-1.3	1.0	1.1	-1.3	1.3	-1.4	-1.6	1.1	1.5	-0.9	-1.3
Sensitivity / hurt feelings	0.2	0.4	1.3	-0.9	-0.6	-0.9	0.1	-0.7	-0.8	0.5	0.1	-0.9	0.6	-1.1	0.6	-0.2	0.4	-0.3	0.7	0.6
Frequency of depressed mood in last 2 weeks	2.1	3.0	4.6	-2.1	-1.3	-1.8	-1.1	-2.1	-1.9	1.8	-1.0	-1.9	2.1	-2.1	2.0	1.0	-0.4	-1.9	1.7	2.0
Hearing difficulty/problems: Yes	0.2	0.4	2.4	0.5	0.6	0.3	0.2	0.3	0.6	0.0	-0.7	-0.1	-0.7	1.5	-0.5	-0.7	-0.6	0.8	0.0	-0.2
Relative age of first facial hair	0.1	0.3	2.6	-0.2	0.6	0.3	0.7	0.2	0.1	0.0	-0.3	1.6	-0.5	-0.1	-0.1	-0.5	-0.1	-0.3	-0.4	-0.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.6	0.4	0.8	-0.2	0.5	0.0	0.3	0.1	-0.3	0.1	-0.6	0.4	-0.2	0.0	0.2	0.2	-0.2	-0.0
Ever used hormone-replacement therapy (HRT)	0.4	0.5	1.5	0.2	0.4	0.9	0.6	0.9	0.1	-0.9	0.9	0.3	-0.9	0.3	-0.7	-1.2	0.6	0.6	-0.5	-0.9
Ever had hysterectomy (womb removed)	1.7	1.9	5.5	-2.3	-1.2	-0.5	-1.4	-1.3	-1.9	1.3	-1.2	-0.7	1.5	-0.9	1.5	1.5	-0.9	-1.4	1.6	1.4
Systolic blood pressure, automated reading	1.4	4.1	8.3	0.5	2.3	1.7	2.5	1.8	1.8	-2.3	2.9	0.9	-1.0	2.7	-1.8	-1.9	2.8	1.5	-2.5	-1.9
Eye problems/disorders: Diabetes related eye disease	1.4	1.6	2.4	0.7	1.5	1.3	1.5	1.2	1.1	-1.4	1.4	1.5	-1.0	0.3	-1.3	-1.1	1.5	0.9	-1.5	-1.3
Angina	0.8	1.0	2.1	1.3	0.9	1.1	1.3	1.1	1.4	-1.1	0.6	0.7	-1.4	0.5	-1.0	-1.0	0.4	0.5	-1.0	-1.1
Medication for hormone replacement therapy	0.8	0.9	2.2	0.9	1.1	0.9	0.7	0.9	0.8	-0.9	0.8	1.5	-1.1	1.4	-0.9	-0.6	0.9	1.1	-0.5	-0.9
Vitamin and mineral supplements	2.8	3.7	5.0	-1.6	-2.0	-1.8	-2.1	-1.9	-1.8	2.1	-1.9	-1.5	2.2	-1.9	2.2	2.0	-1.3	-2.2	1.9	2.0
Supplements: Zinc	0.1	0.1	0.3	0.2	0.1	0.4	0.1	0.4	0.3	-0.3	0.1	-0.3	-0.2	0.3	-0.3	-0.4	0.0	0.0	-0.5	-0.4
Medication: Co-codamol	0.2	0.2	0.7	-0.8	-0.6	-0.3	-0.1	0.0	-0.6	-0.2	0.8	-0.8	0.4	-0.4	0.1	-0.2	0.3	-0.2	0.2	-0.1
Medication: Metformin	1.8	2.5	5.5	1.6	1.7	0.9	1.9	1.5	1.6	-1.2	0.6	1.5	-1.9	2.3	-1.8	-1.3	0.4	2.4	-1.3	-1.6
Diabetes (father)	0.4	0.5	1.8	0.6	-0.0	-0.5	-0.3	-0.3	0.2	0.6	-1.4	-1.2	-0.4	1.1	0.1	0.6	-1.1	0.7	0.6	0.3
Diabetes (mother)	0.2	0.2	0.8	-0.3	0.0	-0.8	-0.0	-0.2	-0.2	0.3	-0.3	-0.8	0.7	-0.9	0.4	0.6	-0.0	-0.6	0.4	0.2
Severe depression (siblings)	0.9	1.0	2.0	-0.8	-1.0	-1.2	-0.9	-1.3	-0.7	1.1	-0.6	-1.0	1.4	0.3	1.3	1.0	-0.3	-0.9	1.0	1.3
Pack years adult smoking proportion	0.2	0.3	1.2	-0.5	-1.1	0.0	-0.1	-0.3	-0.4	0.0	0.5	-0.9	0.8	-1.0	0.4	0.4	-0.0	-0.2	0.4	0.3
Impedance of leg (right)	0.0	0.1	0.3	0.2	-0.1	-0.6	-0.4	-0.2	-0.1	0.4	-0.5	-0.2	-0.2	-0.4	0.1	-0.3	-0.4	0.3	0.5	0.3
Leg fat-free mass (left)	0.0	0.1	0.4	-0.2	0.3	0.5	0.5	0.1	0.2	-0.3	0.4	0.4	0.2	0.7	-0.2	0.4	0.6	-0.1	-0.4	-0.2
Trunk fat percentage	0.2	0.8	4.0	0.2	-0.7	-0.2	-0.5	-0.7	-0.6	0.5	-0.6	-2.0	1.6	1.5	0.7	0.5	-0.0	-0.6	0.7	0.6
Hand grip strength (right)	0.6	1.7	3.3	1.3	1.7	1.4	0.9	1.1	1.4	-1.2	0.8	1.1	-1.1	1.8	-1.4	-1.2	1.0	1.7	-1.3	-1.2
Townsend deprivation index at recruitment	0.7	1.0	2.8	-0.4	-1.7	-0.6	-1.1	-1.0	-0.6	0.9	-0.8	-1.3	0.7	-0.8	1.1	0.9	-1.0	-1.1	1.0	1.0
Current tobacco smoking	1.3	2.2	5.6	-1.2	-2.1	-1.5	-1.0	-1.4	-1.4	1.3	-0.8	-2.4	1.3	-1.5	1.5	1.4	-1.1	-1.3	1.6	1.4
Average weekly fortified wine intake	0.2	0.2	1.7	0.4	0.6	0.0	0.8	0.2	0.3	-0.2	0.3	-0.2	0.0	1.3	-0.3	0.2	0.5	0.6	-0.3	-0.2
Maternal smoking around birth	0.4	0.7	2.5	-0.5	-1.4	-0.4	-0.6	-0.5	-0.6	0.5	-0.3	-1.6	0.7	-0.9	0.7	1.2	-0.7	-0.6	0.7	0.5
Fed-up feelings	0.6	1.2	4.4	-0.8	-1.1	-1.0	-0.4	-1.1	-0.7	0.9	-0.7	-2.0	1.1	-2.1	0.9	0.4	-0.7	-0.8	1.1	0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	2.3	-0.8	-1.0	-1.5	-0.9	-1.2	-1.0	1.0	-0.3	-1.3	1.1	-1.5	1.1	0.4	-0.1	-0.5	1.3	1.2
Relative age voice broke	0.2	0.3	0.9	-0.5	0.9	0.8	0.6	0.1	0.2	-0.2	0.1	0.9	-0.1	0.4	-0.0	0.1	0.6	-0.8	-0.7	-0.1
Taking other prescription medications	0.0	0.1	0.4	0.6	0.2	-0.1	0.1	-0.0	0.5	-0.0	0.1	-0.2	0.0	0.6	-0.0	0.1	0.1	-0.1	-0.2	-0.0
Age when periods started (menarche)	1.1	2.6	6.9	1.2	1.5	2.2	1.8	1.4	1.4	-1.6	1.4	2.6	-2.1	0.3	-1.5	-1.2	1.7	1.6	-1.4	-1.3
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.5	-0.3	-0.4	-0.2	-0.2	-0.3	-0.3	0.2	-0.0	-0.7	0.4	0.1	0.4	0.4	0.1	-0.4	0.4	0.3
Heel bone mineral density (BMD) T-score, automated (left)	2.1	4.7	9.1	-1.3	-3.0	-2.7	-3.0	-2.0	-1.7	2.3	-2.0	-2.3	1.7	-1.9	1.9	1.5	-2.6	-1.2	2.5	2.0
Tinnitus: Yes, but not now, but have in the past	2.9	3.1	4.4	-1.6	-1.6	-1.6	-2.1	-1.8	-2.1	1.8	-1.5	-2.1	1.9	-1.1	1.8	2.1	-1.3	-1.7	1.7	1.8
Qualifications: CSEs or equivalent	0.6	0.8	1.8	1.3	1.0	0.7	1.1	0.7	1.3	-0.6	0.3	0.9	-1.1	0.8	-0.8	-0.9	0.3	0.9	-0.5	-0.7
Serious illness, injury or assault to yourself	0.4	0.4	1.7	-0.5	0.5	0.1	0.5	0.2	0.1	-0.6	1.2	-0.9	0.5	0.5	-0.1	-0.9	1.3	-0.6	-0.8	-0.2
High blood pressure	0.2	0.5	2.3	-0.6	0.3	-0.3	0.5	0.1	0.2	-0.5	1.3	-1.5	-0.0	0.8	-0.2	-0.7	1.2	0.3	-0.6	-0.2
Hayfever, allergic rhinitis or eczema	0.3	0.7	4.4	1.3	0.6	0.3	0.1	0.5	0.8	0.1	-1.2	0.9	-1.4	0.2	-0.4	-0.2	-2.1	0.7	0.2	-0.5
Multivitamins +/- minerals	1.0	1.3	2.9	0.5	1.2	1.0	1.2	1.0	0.8	-1.3	1.5	0.6	-1.3	1.3	-1.3	-0.9	1.1	1.7	-1.1	-1.1
Stomach or abdominal pain in last month	1.1	1.4	3.6	-0.6	-1.9	-1.8	-0.9	-1.3	-0.9	1.2	-0.8	-0.8	1.2	-1.0	1.2	1.0	-1.3	-0.4	1.6	1.1
Supplements: Glucosamine	0.2	0.3	2.1	0.6	0.4	0.4	0.2	0.4	0.2	-0.3	-0.3	1.4	-0.3	0.1	-0.5	-1.0	-0.6	0.2	-0.2	-0.5
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.5	0.8	0.3	0.4	-0.0	0.7	1.1	-0.9	1.1	-0.1	-0.4	1.6	-0.9	-0.8	0.8	0.8	-1.1	-0.7
Medication: Atenolol	1.0	1.3	2.4	0.8	1.0	1.4	1.1	1.0	1.3	-1.2	1.3	0.8	-1.0	0.9	-1.0	-1.0	1.4	1.6	-1.1	-1.0
Medication: Levothyroxine sodium	0.0	0.1	0.4	-0.2	-0.1	0.0	0.2	0.2	0.0	-0.0	-0.1	-0.6	-0.4	0.5	-0.0	-0.2	-0.5	-0.2	0.2	-0.2
Sitting height	0.0	0.1	0.7	-0.3	0.0	0.1	-0.3	-0.2	-0.2	0.2	-0.5	0.6	-0.0	-0.1	0.1	0.8	-0.3	0.1	0.3	0.2
Chronic bronchitis/emphysema (father)	0.3	0.3	1.8	-0.7	-0.1	0.1	-0.6	-0.4	-0.5	0.2	0.1	0.2	0.7	-0.8	0.6	0.0	0.7	-1.4	-0.1	0.5
High blood pressure (mother)	0.3	0.4	1.6	0.3	0.8	0.7	0.3	0.6	0.5	-0.8	1.2	0.4	-0.4	0.2	-0.5	-0.1	1.1	0.5	-0.8	-0.5
Body mass index (BMI)	0.4	1.5	6.5	-0.9	-1.9	-0.6	-1.2	-1.1	-1.2	0.8	-0.5	-2.5	1.9	-0.0	1.1	1.0	-0.6	-1.2	1.0	1.0
Impedance of leg (left)	0.0	0.2	0.8	0.8	0.6	-0.0	0.3	0.3	0.4	-0.1	-0.1	-0.0	-0.8	0.3	-0.4	-0.9	0.1	0.7	-0.1	-0.3
Leg predicted mass (left)	0.0	0.2	0.5	-0.1	0.4	0.6	0.6	0.2	0.3	-0.4	0.4	0.5	0.1	0.7	-0.2	0.3	0.6	-0.0	-0.5	-0.3
Trunk fat mass	0.1	0.5	2.6	0.2	-0.4	0.0	-0.2	-0.4	-0.3	0.3	-0.4	-1.5	1.2	1.6	0.4	0.3	0.1	-0.4	0.3	0.3
Waist circumference	0.1	0.5	1.8	-0.5	-0.6	-0.3	-0.5	-0.6	-0.6	0.4	-0.2	-1.3	1.3	0.7	0.5	0.9	0.1	-0.9	0.2	0.5
Number of incorrect matches in round	0.3	0.6	2.6	-0.6	-0.3	-0.9	-0.8	-0.6	-0.4	0.1	0.8	-1.6	1.1	-0.0	0.3	0.0	1.3	-0.7	-0.3	0.4
Past tobacco smoking	1.1	2.0	3.6	0.4	1.9	1.2	1.9	1.4	1.4	-1.4	1.5	1.0	-1.0	1.8	-1.3	-1.3	1.7	1.0	-1.8	-1.3
Alcohol usually taken with meals	0.1	0.2	1.8	-0.3	0.2	0.3	0.2	0.1	-0.2	0.0	-0.4	1.3	-0.7	0.3	-0.2	-0.3	-0.3	0.3	-0.1	-0.1
Nervous feelings	3.2	6.0	11.0	-3.3	-1.8	-2.7	-1.7	-2.8	-3.2	2.5	-1.5	-2.6	2.8	-2.2	2.7	2.0	-0.9	-2.4	2.5	2.6
Frequency of tenseness / restlessness in last 2 weeks	5.0	7.8	13.0	-3.4	-2.8	-2.7	-2.8	-2.9	-2.9	2.7	-1.8	-3.6	2.7	-3.6	2.9	2.5	-1.5	-2.4	2.5	2.9
Hearing difficulty/problems with background noise	0.6	0.9	2.5	1.0	0.7	1.1	0.2	1.0	1.4	-0.8	0.2	0.8	-1.0	1.3	-1.1	-0.9	0.1	1.6	-0.8	-1.0
Hair/balding pattern: Pattern 2	0.7	0.9	3.7	0.5	0.6	1.2	0.5	1.0	0.6	-1.2	1.4	0.4	-0.7	0.2	-1.0	-1.9	0.9	0.8	-1.2	-1.0
Had menopause	0.8	1.0	2.2	0.3	0.5	1.1	0.3	1.2	1.1	-1.3	1.5	-0.0	-0.7	-0.3	-1.0	-1.5	1.2	1.1	-1.1	-1.1
Had other major operations	0.5	0.7	1.3	-1.1	-0.8	-0.3	-0.9	-0.7	-0.9	0.7	-0.9	-0.6	0.9	-0.6	0.8	0.8	-0.8	-1.1	0.8	0.7
Forced vital capacity (FVC)	0.2	0.7	4.0	-0.8	-0.5	-0.2	-0.9	-0.5	-0.5	0.7	-1.1	0.7	0.5	-2.0	0.6	0.7	-1.0	-0.7	0.5	0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.7	5.0	-0.3	-1.6	-1.9	-2.0	-1.1	-0.8	1.4	-1.6	-1.1	0.3	-1.0	0.9	0.9	-2.2	-0.3	1.6	0.9
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	3.3	1.8	-0.1	0.2	-0.2	0.7	0.7	-0.4	-0.1	-0.1	-1.3	-0.1	-0.7	-0.8	-1.0	0.9	-0.1	-0.7
Qualifications: None of the above	1.9	4.0	6.0	2.4	1.4	1.8	1.6	2.2	2.4	-2.4	2.3	1.5	-1.5	1.6	-2.1	-2.1	1.8	2.5	-2.0	-2.2
Financial difficulties in last 2 years	0.5	0.6	3.8	-0.7	-0.9	-0.4	-0.9	-0.6	-0.4	0.3	0.2	-2.0	0.9	-0.7	0.6	0.9	0.4	-1.0	0.0	0.5
Mouth/teeth dental problems	0.5	0.8	2.3	-1.4	-0.6	-0.4	-1.0	-0.9	-0.7	0.4	0.5	-0.6	1.5	-1.4	0.9	0.7	0.9	-1.3	-0.1	0.9
Heart attack	0.2	0.2	2.4	0.5	0.1	0.4	0.0	0.2	0.4	-0.2	0.2	0.2	0.1	1.6	-0.2	-0.3	0.7	0.1	-0.2	-0.2
Allergy	0.6	1.4	6.1	0.1	0.5	1.5	1.2	1.0	0.7	-1.4	1.9	0.3	-0.1	0.6	-1.0	-0.9	2.5	0.7	-1.5	-0.9
Pain all over the body in last month	0.1	0.2	0.4	-0.4	0.2	0.5	0.4	-0.3	-0.6	0.2	-0.1	0.6	0.3	-0.3	0.4	0.4	0.0	-0.6	0.3	0.4
Diabetes (self-reported)	3.8	5.9	8.3	1.8	2.9	2.0	2.8	2.5	2.4	-2.4	1.9	0.7	-2.8	2.9	-2.7	-2.7	1.6	2.7	-2.5	-2.6
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	3.5	0.2	-0.6	-0.7	-0.3	-0.3	-0.5	0.8	-1.1	0.3	-0.3	-1.4	0.3	0.2	-1.9	-0.2	0.8	0.3
Medication: Ramipril	0.3	0.4	1.1	-0.1	1.0	0.9	1.0	0.5	0.9	-0.5	0.1	0.5	-0.6	0.7	-0.5	-0.8	0.3	0.1	-0.6	-0.5
Medication: Simvastatin	2.6	3.7	5.2	1.7	2.1	1.6	1.9	2.0	1.9	-2.2	2.1	0.9	-1.9	1.8	-2.1	-1.8	2.3	1.9	-2.3	-2.1
Fluid intelligence score	0.3	0.7	1.7	-1.3	-0.9	-1.0	-0.7	-0.7	-1.1	0.8	-0.7	-0.5	0.4	-0.3	0.8	0.9	-0.8	-0.8	0.8	0.7
Illnesses of siblings	0.5	0.6	3.3	1.2	0.4	-0.1	0.1	0.5	1.0	-0.2	-0.1	1.8	-1.0	0.6	-0.8	-0.2	-0.7	1.4	-0.3	-0.6
Neuroticism score	1.0	2.1	4.9	-2.2	-1.2	-1.7	-0.6	-1.6	-1.8	1.4	-0.7	-1.5	1.5	-2.1	1.5	0.9	-0.1	-1.0	1.6	1.5
Weight	0.0	0.2	1.0	-0.3	-0.4	0.3	-0.1	-0.3	-0.3	0.1	-0.1	-1.0	0.9	1.0	0.3	0.6	0.3	-0.5	0.1	0.2
Impedance of arm (right)	0.1	0.6	2.8	1.0	1.7	-0.0	0.8	0.1	0.5	0.0	-0.2	1.3	-0.3	1.7	-0.3	-0.1	0.5	0.5	-0.1	-0.1
Arm fat percentage (right)	0.3	1.1	3.8	-0.6	-1.1	-0.5	-0.8	-1.0	-1.0	0.8	-0.6	-2.0	1.9	1.0	1.0	0.8	-0.2	-1.1	0.9	0.9
Trunk fat-free mass	0.1	0.8	1.6	0.0	0.8	1.1	1.0	0.8	0.7	-1.0	1.0	1.3	-1.0	0.4	-0.9	-0.4	1.0	0.5	-1.2	-0.9
Hip circumference	0.1	0.4	2.1	0.2	-0.8	0.1	-0.6	-0.4	-0.5	0.3	-0.5	-1.4	1.1	0.7	0.4	0.8	-0.4	-0.6	0.5	0.3
Time employed in main current job	0.4	0.5	1.7	-0.6	-0.5	-0.2	-0.4	-0.8	-0.7	0.6	-0.6	-0.9	1.3	-0.3	0.8	0.8	-0.7	-0.7	0.9	0.8
Alcohol intake versus 10 years previously	0.1	0.2	0.9	0.9	0.0	0.0	0.8	0.4	0.7	-0.0	-0.3	-0.4	-0.1	-0.2	-0.2	-0.3	-0.5	-0.1	-0.1	-0.3
Father’s age at death	0.1	0.1	0.4	-0.1	0.6	-0.0	0.5	0.2	0.4	-0.1	0.1	0.6	-0.5	0.2	-0.3	-0.6	0.4	0.3	-0.3	-0.2
Worrier / anxious feelings	0.7	1.4	3.9	-2.0	-0.4	-1.3	-0.7	-1.5	-1.7	1.4	-1.1	-0.2	1.0	-0.7	1.3	0.8	-0.1	-1.2	1.3	1.4
Frequency of tiredness / lethargy in last 2 weeks	1.7	2.7	4.8	-2.0	-1.9	-2.2	-1.4	-1.7	-1.5	1.6	-1.1	-1.4	1.3	-2.0	1.7	1.4	-1.4	-1.7	1.8	1.5
Falls in the last year	4.6	6.3	10.0	-2.8	-3.2	-3.1	-3.0	-2.6	-2.3	2.2	-0.9	-3.2	2.5	-2.6	2.5	2.4	-1.2	-2.0	2.6	2.4
Hair/balding pattern: Pattern 3	0.2	0.2	0.7	-0.1	0.3	0.8	0.7	0.5	0.4	-0.6	0.5	0.2	-0.4	-0.3	-0.5	-0.5	0.5	0.3	-0.5	-0.5
Number of live births	0.5	0.7	2.9	-0.8	-0.9	-0.1	-0.7	-0.7	-0.7	0.7	-0.8	-1.0	0.5	-1.7	0.8	0.8	-0.3	-0.6	1.0	0.8
Forced expiratory volume in 1-second (FEV1)	0.2	0.5	2.0	0.3	1.0	1.2	0.7	0.7	0.7	-0.6	0.1	1.4	-0.5	-0.3	-0.7	-0.5	0.3	0.3	-0.9	-0.6
Pulse rate	0.3	0.4	1.5	-0.4	-0.8	-1.2	-0.5	-0.6	-0.3	0.7	-0.8	-0.1	-0.0	-1.0	0.4	0.3	-1.1	-0.1	0.9	0.5
Happiness	2.6	3.1	8.1	1.9	1.6	1.3	1.5	1.9	2.0	-1.8	1.3	1.0	-2.2	0.8	-2.3	-1.9	1.2	2.8	-1.5	-2.0
Noisy workplace	0.3	0.3	1.6	0.0	-0.2	-0.2	-1.3	-0.5	-0.3	0.4	-0.2	-0.8	0.8	-0.2	0.6	0.7	0.3	-0.8	0.5	0.5
Qualifications: A levels/AS levels or equivalent	2.6	5.8	8.0	-2.3	-2.5	-2.2	-2.0	-2.6	-2.5	2.8	-2.7	-1.6	2.2	-1.9	2.6	2.8	-2.3	-2.1	2.8	2.7
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.6	3.9	-0.0	1.4	0.4	0.9	0.5	0.5	-0.5	0.5	2.0	-0.4	0.8	-0.5	-0.1	1.1	0.2	-0.7	-0.5
Mouth/teeth dental problems: Dentures	0.2	0.3	1.7	0.4	-0.5	0.2	-0.3	0.1	-0.2	0.2	-0.9	-0.9	-0.6	0.3	-0.1	0.2	-1.3	0.6	0.7	-0.1
Asthma	2.1	4.2	8.8	-2.3	-2.0	-3.0	-2.6	-2.0	-2.0	2.0	-1.0	-1.4	2.0	-2.0	2.1	1.9	-1.1	-2.5	1.9	2.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.2	0.8	-0.0	-0.4	-0.2	-0.1	-0.2	0.5	-1.1	0.5	-0.4	-0.3	0.1	0.2	-1.0	-0.1	0.6	0.2
Medication: Cholesterol lowering	0.4	0.6	2.2	0.7	0.9	0.7	0.6	0.5	0.9	-0.7	0.5	-0.3	-0.7	1.5	-0.7	-0.6	0.9	0.7	-0.8	-0.6
Depression (self-reported)	0.3	0.4	1.2	0.1	0.8	0.8	0.8	0.7	0.3	-0.6	0.7	0.0	-0.4	0.7	-0.6	-1.1	1.0	0.3	-0.4	-0.5
Medication: Lansoprazole	1.9	2.1	3.6	-1.0	-1.9	-1.8	-1.7	-1.5	-1.3	1.6	-1.2	-1.1	1.1	-1.9	1.5	0.7	-1.5	-1.3	1.6	1.5
Prospective memory result	1.3	1.5	3.5	-0.5	-1.2	-1.6	-1.5	-1.4	-1.0	1.3	-1.0	-1.9	1.6	-0.3	1.3	1.1	-0.8	-1.3	1.0	1.3
Lung cancer (father)	0.3	0.4	1.4	-0.5	-0.4	-1.0	-1.2	-0.8	-0.5	0.6	-0.0	-0.2	0.9	0.3	0.6	0.5	0.1	-0.2	0.5	0.7
Illnesses of mother	0.4	0.5	1.3	-0.7	-0.7	-0.5	-0.5	-1.0	-0.9	0.7	-0.5	-0.6	1.2	0.1	0.8	0.6	0.1	-0.8	0.6	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	5.2	1.6	2.0	2.2	1.7	1.5	1.7	-1.4	0.3	2.3	-1.9	0.7	-1.6	-1.2	0.5	1.3	-1.7	-1.5
Pulse wave Arterial Stiffness index	0.1	0.2	1.5	-0.3	-0.4	0.4	-0.5	0.0	0.3	-0.2	-0.1	-1.2	0.3	-0.0	-0.1	0.0	-0.0	0.3	0.2	-0.2
Impedance of arm (left)	0.2	0.9	3.0	1.5	1.7	0.2	1.0	0.4	0.8	-0.2	-0.1	1.7	-0.7	1.6	-0.5	-0.4	0.6	0.8	-0.3	-0.3
Arm fat mass (right)	0.1	0.5	2.1	-0.4	-0.8	-0.1	-0.4	-0.6	-0.7	0.4	-0.4	-1.4	1.4	1.1	0.6	0.6	0.0	-0.7	0.5	0.5
Trunk predicted mass	0.2	0.9	1.8	0.1	0.9	1.1	1.1	0.9	0.8	-1.1	1.0	1.4	-1.0	0.6	-1.0	-0.4	1.1	0.6	-1.3	-1.0
Standing height	0.3	3.2	10.0	1.1	2.8	1.7	2.1	1.4	1.6	-1.2	0.5	3.2	-2.0	2.1	-1.7	-0.7	1.4	1.6	-1.7	-1.4
Length of working week for main job	0.8	0.9	2.3	1.0	0.9	0.5	1.0	1.1	1.0	-0.8	0.5	0.8	-0.9	1.5	-1.2	-0.8	0.2	1.4	-0.9	-1.1
Exposure to tobacco smoke at home	1.6	1.8	4.7	1.6	1.0	1.5	0.9	1.4	1.2	-1.2	0.3	2.2	-1.6	1.2	-1.5	-1.1	0.3	1.9	-0.8	-1.4
Breastfed as a baby	4.4	5.5	8.5	2.1	2.6	2.6	2.1	2.6	2.4	-2.5	1.7	2.9	-2.2	1.4	-2.7	-2.0	1.5	2.9	-2.2	-2.6
Tense / ‘highly strung’	1.1	1.9	3.4	-1.7	-0.9	-1.6	-0.2	-1.6	-1.8	1.7	-1.7	-0.6	1.2	-0.8	1.4	1.4	-1.1	-0.5	1.8	1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	1.8	0.6	-0.4	0.4	0.2	-0.0	-0.2	-0.1	0.3	-1.3	0.0	-0.5	0.1	0.3	0.5	-0.0	0.1	0.1
Hair/balding pattern: Pattern 4	0.7	1.6	5.4	1.7	2.3	0.9	1.4	1.2	1.1	-0.9	0.1	1.1	-1.4	1.7	-1.2	-0.9	0.7	1.1	-0.9	-1.3
Birth weight of first child	1.8	3.3	6.9	1.9	2.4	1.6	2.0	1.7	1.8	-1.8	1.7	1.5	-1.0	2.6	-1.7	-1.7	1.8	1.8	-1.9	-1.6
Peak expiratory flow (PEF)	0.1	0.2	0.5	-0.7	-0.3	0.3	-0.5	-0.4	-0.6	0.3	-0.3	0.3	0.6	-0.6	0.4	0.5	0.1	-0.4	0.2	0.4
Pulse wave reflection index	0.3	0.4	1.7	-0.3	-0.2	0.6	-0.0	0.3	0.7	-0.8	1.3	-1.0	0.7	-0.1	-0.2	-0.5	1.3	0.2	-0.6	-0.4
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.7	0.3	0.7	0.8	0.7	0.8	0.5	-0.6	0.2	0.8	-0.6	0.4	-0.6	-0.9	0.3	0.2	-0.7	-0.7
Loud music exposure frequency	0.8	0.9	1.8	1.3	0.6	1.3	0.9	1.1	0.9	-1.1	1.1	0.5	-0.7	0.6	-0.8	-1.3	0.7	0.3	-1.0	-1.1
Qualifications: O levels/GCSEs or equivalent	4.6	7.4	9.9	-2.7	-2.9	-2.8	-2.6	-2.9	-2.6	3.1	-2.9	-2.3	2.1	-2.2	2.8	3.1	-2.6	-2.6	2.9	2.9
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.0	0.3	0.6	0.5	0.8	0.6	0.6	-0.6	0.2	1.0	-0.7	0.8	-0.6	-0.3	-0.3	1.0	-0.0	-0.6
Blood clot in the leg (DVT)	0.1	0.1	0.6	0.8	-0.0	-0.2	-0.5	-0.3	0.2	0.4	-0.5	-0.5	0.2	0.6	0.1	0.2	-0.4	-0.0	0.3	0.3
Medication: Paracetamol	0.2	0.3	2.2	0.4	-0.1	0.3	0.2	-0.4	-0.5	0.6	-1.5	0.3	0.2	0.3	0.3	0.5	-1.0	-0.4	0.6	0.5
Headache pain in last month	0.8	1.4	2.3	-1.5	-1.2	-1.2	-1.2	-1.1	-1.1	1.1	-0.9	-1.5	0.8	-1.4	1.2	1.2	-0.8	-1.0	1.3	1.1
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.8	-0.5	-0.3	0.2	-0.4	0.1	-0.2	-0.1	0.3	0.9	0.1	-0.7	-0.0	-0.0	-0.1	0.2	0.1	-0.1
Glaucoma (self-reported)	1.8	2.1	5.0	2.0	1.5	1.4	2.0	1.5	1.7	-1.3	0.2	1.7	-2.2	-0.3	-1.5	-1.6	-0.1	0.8	-1.3	-1.6
Gout (self-reported)	0.7	1.0	1.7	0.7	0.5	1.1	1.3	1.1	1.0	-1.2	1.2	0.5	-1.1	0.6	-1.0	-1.3	0.6	0.9	-1.1	-1.1
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	1.0	0.7	0.2	0.8	1.0	0.8	0.8	-0.6	0.4	-0.2	-1.0	0.4	-0.6	-0.9	0.2	0.3	-0.6	-0.7
Medication: Amlodipine	1.7	2.4	4.2	-1.3	-2.0	-2.0	-1.9	-1.8	-1.2	1.6	-0.9	-1.0	1.4	-2.0	1.7	1.0	-1.2	-1.5	1.5	1.7
Medication: Ventolin 100micrograms inhaler	1.0	1.3	3.9	-0.7	-1.7	-1.1	-1.2	-0.8	-0.9	1.2	-1.4	-0.8	0.8	-1.2	0.9	0.8	-2.0	-0.2	1.4	0.9
Birth weight	0.7	1.6	5.7	1.6	1.0	2.4	0.8	1.1	1.1	-1.2	0.3	2.1	-1.7	0.1	-1.2	-1.1	0.4	1.2	-0.9	-1.1
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.1	0.1	-1.1	-0.9	-0.6	-0.6	-0.3	0.7	-0.6	-0.9	0.3	-1.0	0.6	0.5	-1.0	-0.6	0.7	0.6
High blood pressure (siblings)	0.8	1.2	4.2	-2.0	-0.8	-0.6	-0.7	-1.0	-1.4	0.7	-0.3	-1.6	1.3	-0.9	1.2	0.5	0.2	-1.6	0.7	1.0
Forced vital capacity (FVC), Best measure	0.1	0.5	2.7	0.5	0.6	0.9	0.0	0.5	0.6	-0.3	-0.6	1.6	-0.9	-0.8	-0.5	-0.1	-0.7	0.5	-0.4	-0.5
Body fat percentage	0.3	1.2	6.2	-0.3	-1.1	-0.5	-0.8	-0.9	-0.9	0.7	-0.7	-2.5	1.9	1.2	0.9	0.6	-0.2	-0.9	0.9	0.8
Leg fat percentage (right)	0.6	2.3	10.1	-1.1	-1.9	-0.9	-1.5	-1.4	-1.6	1.0	-0.6	-3.2	2.5	0.3	1.5	0.9	-0.2	-1.7	1.2	1.3
Arm fat-free mass (right)	0.1	0.3	0.6	-0.3	0.1	0.8	0.6	0.6	0.4	-0.7	0.7	0.1	-0.4	0.3	-0.6	-0.3	0.8	0.4	-0.8	-0.6
Exposure to tobacco smoke outside home	0.7	1.0	4.7	0.7	-1.0	-0.3	-1.1	-0.4	-0.4	0.9	-2.0	-0.1	-0.2	-1.2	0.5	0.5	-2.2	-0.5	1.2	0.4
Comparative body size at age 10	0.5	1.4	4.0	-0.4	-2.0	-1.2	-1.6	-0.9	-0.7	0.9	-0.7	-0.9	1.1	-1.7	1.1	1.3	-1.4	-0.8	1.2	0.9
Number of full brothers	2.2	2.8	4.8	1.9	1.5	2.0	1.2	2.0	1.8	-1.8	0.8	0.7	-2.2	1.4	-1.9	-2.2	0.7	1.7	-1.6	-2.0
Worry too long after embarrassment	1.1	1.8	4.4	-2.1	-1.4	-1.6	-0.8	-1.4	-1.8	1.3	-0.5	-1.0	1.5	-1.7	1.3	1.1	-0.3	-1.1	1.2	1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.9	0.2	0.4	0.9	0.6	0.5	0.4	-0.8	1.3	-0.4	-0.6	0.4	-0.4	-0.7	1.4	0.2	-0.5	-0.4
Wheeze or whistling in the chest in last year	2.7	4.8	10.4	-1.9	-2.6	-3.2	-2.4	-2.2	-1.9	2.2	-1.4	-2.3	2.4	-1.6	2.2	1.9	-2.0	-1.6	2.6	2.0
Number of children fathered	0.2	0.2	0.8	-0.4	-0.5	-0.2	-0.2	-0.4	-0.4	0.5	-0.5	0.1	0.1	0.5	0.4	0.2	-0.6	-0.9	-0.0	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.7	0.6	0.2	1.3	0.9	0.6	0.3	-0.8	0.8	-0.3	-0.6	-0.1	-0.5	-0.2	0.6	0.4	-0.7	-0.5
Age at first live birth	0.5	0.9	2.4	0.9	1.2	-0.0	1.6	0.8	0.9	-0.6	0.8	1.3	-0.7	0.9	-0.9	-1.0	0.8	0.7	-1.0	-0.8
Pulse wave peak to peak time	0.2	0.2	2.1	0.5	0.6	-0.2	0.7	0.2	-0.1	0.1	0.1	1.4	-0.6	0.2	-0.1	-0.1	0.1	-0.1	-0.3	-0.0
Health satisfaction	0.3	0.3	1.1	0.2	-0.5	-0.6	-0.9	-0.4	-0.2	0.4	-0.8	-0.3	0.2	-1.1	0.2	0.5	-1.0	0.1	0.8	0.2
Shortness of breath walking on level ground	1.1	1.3	2.8	-0.8	-1.2	-1.4	-1.2	-1.1	-1.7	1.1	-0.9	-0.6	1.1	-1.5	1.1	1.1	-0.9	-1.3	1.1	1.0
Qualifications: College or University degree	1.6	5.0	7.4	-2.6	-1.8	-2.3	-2.3	-2.5	-2.6	2.7	-2.7	-0.8	1.8	-0.8	2.3	2.5	-2.2	-1.9	2.4	2.5
Eye problems/disorders: None of the above	0.2	0.2	0.9	-0.8	-0.2	-0.2	-0.4	-0.2	-0.6	0.1	0.6	0.2	1.0	0.1	0.4	0.4	0.8	-0.3	0.1	0.3
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.8	0.5	0.1	0.4	0.3	0.5	0.9	-0.6	0.4	0.6	-0.0	0.2	-0.5	0.1	-0.3	0.2	-0.3	-0.7
Emphysema/chronic bronchitis	2.5	2.9	7.1	-1.4	-1.5	-1.9	-1.6	-1.5	-1.4	1.8	-1.8	-2.7	1.3	-1.9	1.5	1.7	-1.6	-1.5	1.7	1.5
Medication for pain relief, constipation, heartburn	0.2	0.4	2.4	-0.8	-0.4	-0.3	-0.5	0.1	0.2	-0.5	1.5	-0.6	0.5	-0.8	0.1	0.0	1.0	0.1	-0.2	-0.1
Neck or shoulder pain in last month	0.4	0.5	1.4	1.2	0.3	0.8	0.6	0.9	0.7	-0.8	0.3	-0.2	-0.6	0.9	-0.8	-1.0	-0.3	0.9	-0.4	-0.9
Medication: Blood pressure	0.1	0.1	0.6	0.2	0.2	-0.0	0.6	-0.1	0.2	0.1	-0.3	-0.8	-0.2	0.1	0.1	-0.4	0.1	-0.2	-0.2	0.1
Angina (self-reported)	0.7	0.9	1.7	1.2	0.9	0.9	1.3	1.1	1.3	-1.0	0.6	0.7	-1.3	0.7	-0.9	-0.9	0.5	0.4	-1.0	-1.0
Migraine (self-reported)	0.9	1.1	2.5	-1.4	-0.8	-0.7	-0.9	-1.0	-1.4	1.1	-1.1	-1.0	0.5	-1.6	0.9	1.1	-1.0	-0.7	1.1	1.0
Medication: Ibuprofen	0.2	0.2	0.7	0.4	0.0	-0.8	-0.4	-0.3	-0.4	0.6	-0.9	0.2	-0.0	-0.0	0.2	0.4	-0.5	-0.4	0.5	0.3
Medication: Allopurinol	0.5	0.6	1.6	0.6	0.3	0.8	0.8	0.9	0.6	-1.0	1.2	-0.0	-0.8	0.4	-0.8	-1.3	0.5	0.9	-0.8	-0.9
Medication: Omeprazole	4.6	5.5	8.0	-1.6	-2.1	-2.1	-2.0	-2.5	-2.3	2.7	-2.7	-2.8	2.1	-1.5	2.4	2.8	-2.5	-2.1	2.6	2.5
Medication: Seretide 50 evohaler	2.2	2.5	5.7	-0.8	-1.8	-1.5	-2.2	-1.5	-1.6	1.3	-0.8	-1.9	1.5	-2.4	1.4	1.7	-1.3	-1.5	1.4	1.4
Mean time to correctly identify matches	3.3	6.3	9.4	3.1	2.8	2.5	2.4	2.7	2.5	-2.6	1.7	2.3	-2.8	2.8	-2.7	-2.3	1.6	2.3	-2.5	-2.7
Heart disease (mother)	0.2	0.2	1.4	0.5	0.3	1.2	0.2	0.4	0.5	-0.3	-0.2	0.3	-0.3	-0.5	-0.2	-0.5	-0.1	0.1	-0.4	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.8	2.5	-1.2	-0.3	-0.6	-0.2	-0.9	-1.1	0.7	0.2	-0.1	1.6	0.1	1.2	0.9	0.5	-1.4	0.5	1.1
Whole body fat mass	0.1	0.5	2.8	-0.1	-0.6	-0.0	-0.4	-0.5	-0.5	0.3	-0.4	-1.7	1.4	1.3	0.5	0.5	0.2	-0.7	0.4	0.4
Leg fat mass (right)	0.3	1.0	5.3	-0.6	-1.2	-0.4	-0.9	-0.9	-1.0	0.6	-0.5	-2.3	1.8	0.7	0.9	0.7	-0.1	-1.0	0.7	0.8
Arm predicted mass (right)	0.0	0.2	0.6	-0.3	0.1	0.7	0.6	0.5	0.3	-0.6	0.6	0.1	-0.3	0.3	-0.5	-0.2	0.7	0.2	-0.8	-0.5
Pulse rate, automated reading	0.2	0.6	1.5	-0.5	-0.7	-1.2	-0.7	-0.7	-0.7	0.9	-1.0	-0.6	0.5	0.9	0.6	0.2	-0.8	-0.6	0.9	0.7
Alcohol intake frequency.	0.3	0.7	1.8	0.9	0.3	1.3	1.0	1.0	1.0	-1.1	1.0	0.0	-0.4	0.7	-0.8	-0.8	1.0	0.4	-1.0	-0.9
Comparative height size at age 10	0.3	1.6	3.9	0.5	2.0	1.4	1.8	1.1	0.9	-1.1	0.8	1.2	-1.1	1.6	-1.1	-0.9	1.8	1.1	-1.2	-1.0
Number of full sisters	0.1	0.1	0.4	0.5	-0.0	-0.2	0.4	-0.0	0.2	0.1	-0.2	0.6	0.4	-0.3	0.2	-0.2	-0.4	-0.3	0.2	0.0
Suffer from ‘nerves’	1.3	2.1	6.0	-2.4	-0.6	-1.7	-0.5	-1.6	-2.0	1.5	-0.9	-1.6	1.3	-1.2	1.5	1.2	-0.3	-1.0	1.7	1.6
Overall health rating	0.1	0.3	1.6	0.2	-0.9	-0.6	-0.3	-0.2	-0.1	0.3	-0.4	-0.7	-0.1	-1.3	0.3	-0.1	-0.6	-0.3	0.9	0.1
Chest pain or discomfort	2.2	3.2	5.6	-1.6	-2.4	-1.8	-1.8	-1.7	-1.5	1.8	-1.7	-1.8	1.5	-1.6	1.8	1.6	-2.2	-1.7	1.9	1.7
Had major operations	0.8	1.0	2.0	-0.3	-1.1	-1.1	-0.1	-1.1	-1.0	1.2	-1.4	-0.2	1.2	-0.4	1.0	1.0	-1.0	-1.1	1.2	1.1
Age at last live birth	1.7	2.5	3.8	1.6	1.6	1.1	1.7	1.7	1.6	-1.7	2.0	1.4	-1.3	1.1	-1.6	-1.8	1.8	1.2	-1.9	-1.7
Family relationship satisfaction	0.7	0.9	3.3	-0.4	-1.1	-1.8	-1.1	-1.1	-0.7	1.1	-0.6	-0.2	1.1	-1.3	0.9	0.8	-0.5	-0.8	0.7	1.0
Leg pain on walking	0.1	0.1	0.6	0.3	-0.2	0.1	-0.4	-0.2	-0.3	0.3	-0.8	0.1	0.0	-0.4	0.1	0.0	-0.2	0.0	0.3	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	2.3	-0.3	0.9	0.9	0.5	0.4	0.2	-0.7	1.0	0.4	-0.1	0.1	-0.2	0.2	1.5	-0.6	-0.9	-0.3
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.3	1.2	0.8	1.0	0.8	0.7	0.7	-0.5	-0.0	0.5	-0.5	1.5	-0.7	-0.7	0.1	0.7	-0.7	-0.6
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.9	-0.0	-0.6	-0.7	-0.2	-0.1	0.1	0.3	-0.1	0.3	-0.1	-0.3	-0.0	0.3	-0.9	0.9	0.6	0.2
Medication: Aspirin	1.5	2.0	4.2	0.6	1.8	1.2	1.6	1.2	1.2	-1.3	1.3	1.3	-0.9	2.0	-1.3	-1.3	2.0	0.9	-1.9	-1.2
Supplements: Vitamin C	1.1	1.3	3.1	1.8	0.6	0.8	0.7	1.2	1.2	-1.2	1.2	1.4	-0.9	1.1	-1.3	-1.3	0.3	1.2	-1.0	-1.2
Knee pain experienced in last month	0.5	0.8	2.5	-1.1	-1.3	-0.8	-0.8	-0.8	-0.8	0.8	-0.4	-1.6	1.2	-0.2	0.9	0.5	-0.6	-0.5	1.1	0.8
Hypertension (Self-reported)	0.1	0.3	3.0	-0.7	-0.3	-0.7	-0.1	-0.3	-0.4	0.1	0.6	-1.7	0.3	0.4	0.3	-0.4	0.5	-0.3	0.0	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.8	2.1	4.1	-0.7	-2.0	-1.1	-2.0	-1.3	-1.2	1.3	-1.0	-1.5	1.6	-1.8	1.4	1.6	-1.4	-1.2	1.3	1.4
Illnesses of father: Heart disease	0.2	0.3	1.2	-1.1	-0.8	0.1	-0.9	-0.4	-0.9	0.3	-0.3	-0.1	0.6	-0.3	0.5	0.9	-0.1	-0.2	0.5	0.5
Illnesses of siblings: Diabetes	0.4	0.5	1.7	-0.9	-0.0	0.4	0.0	-0.3	-0.5	-0.2	0.9	-1.3	1.2	-0.9	0.5	0.6	1.2	-0.9	-0.2	0.4
Smoking status: Previous	0.1	0.2	0.9	0.3	-0.6	0.2	-0.9	-0.3	-0.4	0.2	-0.3	0.2	0.5	-0.6	0.3	0.1	-0.3	-0.4	0.5	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.5	0.6	1.1	0.6	0.5	0.7	1.0	-0.5	0.1	1.2	-0.6	0.9	-0.9	-0.2	0.7	1.1	-0.6	-0.7
Whole body fat-free mass	0.1	0.6	1.1	-0.0	0.7	0.9	0.9	0.7	0.6	-0.9	0.9	0.9	-0.6	0.6	-0.7	-0.2	1.0	0.4	-1.1	-0.8
Leg fat-free mass (right)	0.1	0.5	1.1	0.3	0.8	0.9	1.0	0.6	0.6	-0.7	0.6	0.7	-0.3	1.1	-0.6	0.1	0.8	0.2	-0.8	-0.6
Arm fat percentage (left)	0.3	1.0	3.7	-0.4	-1.1	-0.5	-0.7	-0.9	-0.9	0.7	-0.6	-1.9	1.9	1.0	1.0	0.8	-0.1	-1.0	0.8	0.9
Average weekly red wine intake	0.1	0.2	0.5	-0.7	-0.0	-0.7	-0.0	-0.5	-0.6	0.5	-0.5	0.1	0.2	0.3	0.4	0.2	-0.5	-0.2	0.4	0.4
Handedness (chirality/laterality): Left-handed	1.1	1.3	3.4	-0.9	-1.0	-1.2	-0.9	-1.1	-1.3	1.3	-1.8	-0.7	1.0	-0.5	1.0	0.6	-1.9	-0.7	1.4	1.1
Mood swings	1.0	1.7	3.7	-1.9	-1.2	-1.7	-1.0	-1.6	-1.5	1.4	-0.6	-1.1	1.3	-1.4	1.3	1.4	-0.2	-0.7	1.5	1.5
Loneliness, isolation	0.3	0.4	2.0	-0.1	-0.1	0.1	0.4	0.4	0.7	-0.6	0.9	0.7	-0.4	0.5	-0.7	-0.5	0.8	1.4	-0.3	-0.5
Long-standing illness, disability or infirmity	0.1	0.2	1.1	0.1	-0.5	-0.2	-0.1	-0.1	0.2	0.3	-0.6	-1.1	-0.3	0.2	0.1	0.3	-0.7	0.2	0.6	0.1
Ever had bowel cancer screening	0.1	0.1	0.5	-0.7	-0.4	-0.7	-0.4	-0.3	-0.3	0.3	-0.2	0.2	0.3	-0.1	0.2	0.1	-0.4	-0.2	0.5	0.2
Diabetes diagnosed by doctor	1.9	3.1	7.1	1.2	2.1	1.3	2.1	1.7	1.8	-1.6	1.1	-0.0	-2.1	2.7	-2.0	-1.8	1.0	2.3	-1.7	-1.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.5	-0.5	0.3	0.4	0.3	0.2	-0.2	-0.5	1.1	0.5	0.3	0.2	-0.2	0.4	1.2	-0.2	-0.6	-0.2
Friendships satisfaction	5.4	6.7	12.6	-1.3	-3.0	-3.3	-2.8	-2.4	-2.2	2.9	-2.9	-2.3	1.7	-2.9	2.3	2.0	-3.6	-1.7	3.0	2.3
Qualifications: nursing, teaching	0.4	0.7	2.0	-0.8	-0.5	-0.7	-0.5	-0.8	-0.7	1.1	-1.4	0.7	0.3	-0.5	0.7	1.0	-1.2	-0.7	0.7	0.9
Commuting to job workplace: Walk	0.2	0.2	0.9	0.1	0.4	0.2	-0.3	-0.2	-0.5	0.4	-0.8	0.9	0.1	0.2	0.3	0.3	-0.2	-0.9	0.1	0.2
Eye problems/disorders: Cataract	0.2	0.2	0.6	0.7	0.8	0.4	0.7	0.2	0.7	-0.2	-0.1	0.0	-0.2	0.6	-0.3	-0.3	0.1	-0.0	-0.4	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	3.4	1.1	0.6	-0.1	0.8	0.4	0.4	-0.1	-0.1	1.8	-0.7	0.1	-0.4	-0.4	-0.1	0.2	-0.1	-0.4
Medication for cholesterol	1.1	1.7	5.4	-0.3	-0.8	-1.2	-0.9	-1.2	-0.9	1.6	-2.3	-0.2	1.1	-1.6	1.1	1.1	-2.1	-1.3	1.3	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	1.3	-0.3	-0.6	-0.3	-0.3	-0.1	-0.3	0.2	-0.4	-1.1	-0.4	-0.3	0.0	0.0	-0.6	0.3	0.3	0.1
Back pain experienced in last month	1.0	1.5	3.6	-0.9	-1.8	-1.3	-1.9	-1.1	-1.2	1.1	-0.8	-1.2	1.1	-1.3	1.1	0.8	-1.1	-1.0	1.4	1.0
Mineral and other dietary supplements	1.0	1.3	3.1	-1.1	-1.0	-0.8	-0.9	-1.2	-0.9	1.1	-0.8	-1.3	1.4	-1.0	1.4	1.8	-0.2	-1.2	1.0	1.3
Breast cancer (self-reported)	2.7	3.3	5.3	1.8	1.7	1.5	1.3	2.0	1.8	-2.2	2.3	1.8	-1.6	1.4	-2.0	-1.4	1.4	2.0	-2.1	-2.1
Asthma (self-reported)	1.8	3.6	7.3	-2.0	-2.0	-2.7	-2.5	-1.9	-1.9	1.9	-1.1	-1.2	1.7	-1.8	1.9	1.8	-1.3	-2.2	1.9	1.8
Osteoporosis (self-reported)	5.5	6.9	10.5	1.6	3.2	2.6	3.2	2.9	2.6	-2.9	2.8	1.2	-2.5	2.6	-2.7	-2.4	2.7	2.3	-2.8	-2.8
Osteoarthritis (self-reported)	0.3	0.4	4.1	0.0	-0.4	-0.4	-0.3	-0.2	-0.4	0.4	-0.5	-2.0	0.6	0.1	0.4	0.1	-0.4	-0.2	0.6	0.2
Medication: Aspirin	2.1	2.7	7.1	0.7	1.9	1.4	1.7	1.4	1.4	-1.6	1.6	1.5	-1.1	2.7	-1.6	-1.5	2.1	1.2	-2.2	-1.4
Medication: Gliclazide	1.7	1.9	4.5	0.1	1.5	0.6	1.6	1.1	1.1	-1.5	2.1	0.9	-0.7	2.1	-1.4	-0.9	1.8	1.5	-1.6	-1.2
Illnesses of father: None of the above (group 1)	1.0	1.3	1.8	1.4	1.2	1.3	1.0	1.1	1.4	-1.2	1.1	1.3	-1.1	0.7	-1.2	-0.9	0.8	0.9	-1.2	-1.1
Smoking status: Current	1.5	2.4	5.3	-1.0	-2.0	-1.6	-1.1	-1.5	-1.4	1.5	-1.2	-2.3	1.1	-1.4	1.5	1.7	-1.4	-1.2	1.8	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	2.7	1.1	0.8	1.6	1.0	1.1	1.3	-1.2	0.7	1.7	-1.1	0.3	-1.1	-0.7	0.6	0.8	-1.6	-1.1
Whole body water mass	0.1	0.4	0.9	-0.1	0.6	0.8	0.9	0.6	0.5	-0.7	0.7	0.8	-0.5	0.6	-0.6	-0.1	0.8	0.4	-0.9	-0.7
Leg predicted mass (right)	0.1	0.4	1.0	0.2	0.7	0.9	1.0	0.5	0.5	-0.6	0.5	0.6	-0.2	1.0	-0.5	0.1	0.8	0.2	-0.8	-0.6
Arm fat mass (left)	0.1	0.6	2.3	-0.3	-0.9	-0.1	-0.5	-0.6	-0.6	0.4	-0.4	-1.5	1.4	1.0	0.6	0.7	0.0	-0.6	0.5	0.5
Number of self-reported non-cancer illnesses	1.2	2.1	4.7	-1.3	-1.3	-1.4	-1.2	-1.4	-1.3	1.5	-1.4	-1.6	1.3	-1.5	1.6	0.9	-1.3	-2.2	1.5	1.4
Average weekly champagne plus white wine intake	0.1	0.2	0.6	0.4	0.4	-0.1	-0.1	-0.0	0.1	0.2	-0.7	0.4	-0.5	0.8	-0.2	0.0	-0.4	0.6	0.5	0.1
Miserableness	0.9	1.5	4.4	-1.4	-0.9	-0.7	-0.0	-1.3	-1.4	1.1	-0.6	-1.6	1.2	-2.1	1.4	1.1	-0.3	-1.6	1.2	1.3
Guilty feelings	1.7	2.6	10.1	-1.4	-2.2	-1.4	-1.8	-1.2	-1.4	1.0	-0.4	-3.2	1.5	-2.5	1.4	1.0	-1.0	-1.2	1.3	1.2
Wears glasses or contact lenses	0.7	0.8	2.4	1.1	0.3	0.5	0.6	1.0	0.8	-0.8	0.5	-0.5	-0.9	1.6	-1.0	-1.1	0.1	1.2	-0.8	-1.0
Ever taken oral contraceptive pill	0.6	0.7	2.7	0.5	-1.1	-1.1	-1.0	-0.3	-0.0	0.7	-0.9	-0.3	0.3	-1.6	0.4	0.7	-1.6	-0.1	0.9	0.3
Hearing aid user	0.5	0.6	2.9	1.6	0.6	0.6	0.3	0.6	0.7	-0.3	-0.3	-0.0	-0.6	1.7	-0.6	-0.6	-0.4	0.4	-0.7	-0.5
Mother’s age at death	0.3	0.4	2.2	0.4	0.3	0.2	-0.1	-0.1	-0.3	0.5	-1.3	1.5	-0.1	0.6	0.2	0.2	-1.0	-0.5	0.5	0.2
Financial situation satisfaction	1.7	2.1	4.2	1.5	0.8	1.5	1.4	1.6	2.0	-1.8	1.8	0.3	-1.3	0.5	-1.6	-1.6	1.0	1.4	-1.8	-1.7
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.1	-0.0	0.2	1.0	0.4	0.6	0.3	-0.5	0.2	0.8	-0.8	1.0	-0.6	-0.4	0.1	0.6	-0.4	-0.5
Commuting to job workplace: Public transport	1.0	1.2	2.1	0.7	1.4	0.6	1.5	1.2	1.3	-1.2	1.1	1.0	-1.2	0.5	-1.1	-1.3	1.2	0.5	-1.2	-1.3
Eye problems/disorders: Glaucoma	3.9	4.7	9.1	2.8	1.8	1.8	2.5	2.4	2.7	-2.2	1.3	1.6	-3.0	0.2	-2.4	-2.5	0.3	1.9	-2.1	-2.6
Medication: Blood pressure	0.2	0.3	1.4	-0.9	-0.4	-0.6	-0.6	-0.4	-0.5	-0.0	1.1	-1.2	0.3	-0.1	0.3	0.2	0.7	0.1	0.2	0.3
Pain type(s) experienced in last month: Hip pain	1.4	1.8	4.0	-1.3	-1.8	-1.6	-1.2	-1.3	-1.3	1.1	-0.4	-1.8	1.3	-2.0	1.4	1.2	-0.6	-1.0	1.3	1.2
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.1	-0.4	0.5	0.5	0.5	0.5	0.0	-0.6	0.6	0.4	-0.9	0.1	-0.6	-1.0	0.2	0.7	-0.3	-0.5
High cholesterol (Self-reported)	0.4	0.6	1.1	-0.2	0.5	0.8	0.9	0.9	0.4	-1.0	1.0	-0.7	-0.7	0.2	-0.9	-1.0	0.9	0.8	-0.9	-0.9
Medication: Bendroflumethiazide	0.4	0.6	3.0	-1.3	-0.5	-0.4	-0.7	-0.9	-0.7	0.4	0.6	-1.7	0.9	0.6	0.6	0.3	1.0	-0.0	0.3	0.9
Medication: Paracetamol	0.8	1.3	4.2	0.1	-1.2	-0.4	-0.7	-1.1	-1.1	1.3	-2.0	-0.6	0.6	-0.6	1.0	1.1	-1.9	-1.0	1.4	1.1
Medication: Lisinopril	0.5	0.7	2.2	0.9	0.4	0.3	0.1	0.7	0.9	-1.0	1.5	-0.3	-0.2	0.8	-0.7	-0.6	1.5	0.7	-0.9	-0.8
Medication: Atorvastatin	0.6	0.7	1.4	-0.5	-1.0	-0.5	-0.7	-0.7	-0.6	0.9	-1.2	-1.1	0.6	-0.5	0.8	0.6	-1.1	-0.7	1.1	0.8
Illnesses of father: High blood pressure	3.5	4.3	12.2	-1.6	-2.3	-1.8	-2.4	-2.0	-1.8	2.2	-2.3	-3.5	1.4	-1.2	1.9	1.8	-2.6	-1.1	2.3	1.9
Alcohol drinker status: Never	0.6	0.7	2.6	-0.3	0.6	1.4	0.6	0.7	-0.2	-1.1	1.5	0.7	-0.4	0.1	-0.4	-0.6	1.6	-0.5	-1.1	-0.6
Ever smoked	1.7	3.0	6.5	-0.7	-2.2	-1.8	-1.8	-1.6	-1.7	1.7	-1.8	-1.4	1.1	-2.5	1.6	1.6	-2.2	-1.2	2.3	1.5
Basal metabolic rate	0.0	0.2	0.5	-0.2	0.3	0.7	0.6	0.3	0.3	-0.5	0.5	0.3	-0.1	0.6	-0.4	0.2	0.7	0.1	-0.7	-0.4
Leg fat percentage (left)	0.4	1.6	9.8	-0.7	-1.6	-0.5	-1.0	-1.0	-1.2	0.7	-0.4	-3.1	2.1	0.6	1.2	0.5	-0.0	-1.5	0.8	0.9
Arm fat-free mass (left)	0.0	0.1	0.6	-0.8	-0.2	0.4	0.2	0.0	-0.1	-0.3	0.5	-0.4	0.2	0.1	-0.1	0.3	0.5	-0.1	-0.3	-0.1
Number of operations (self-reported)	1.6	2.4	3.8	-1.0	-1.7	-0.9	-1.5	-1.4	-1.9	1.6	-1.9	-1.7	1.6	-1.1	1.5	1.6	-1.6	-1.4	1.8	1.5
Average weekly beer plus cider intake	0.5	0.7	3.8	-0.4	-0.6	-0.5	-0.5	-0.6	-0.3	0.5	-0.5	-1.9	1.6	-0.8	0.8	0.9	-0.5	-1.1	0.6	0.6
Irritability	1.7	2.8	6.4	-1.5	-1.8	-2.5	-1.0	-1.9	-1.5	1.9	-1.5	-1.8	1.6	-1.3	1.7	1.4	-1.6	-1.5	1.8	1.7
Risk taking	0.4	0.6	0.9	0.7	0.6	0.7	0.9	0.8	0.8	-0.9	0.9	0.7	-0.6	0.7	-0.9	-0.8	0.6	0.9	-1.0	-0.9
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.0	1.4	0.5	0.5	0.7	1.0	0.7	-0.6	-0.0	1.2	-1.4	0.2	-1.0	-1.0	-0.6	0.6	-0.5	-1.0
Fractured/broken bones in last 5 years	0.2	0.3	0.9	-0.5	-0.1	-0.4	-0.1	-0.3	-0.4	0.4	-0.9	-1.0	-0.6	-0.7	0.1	-0.2	-0.7	-0.0	0.5	0.2
Age started oral contraceptive pill	0.6	0.8	2.7	-0.4	1.2	0.9	1.3	0.7	0.3	-0.9	1.1	0.5	-0.3	0.2	-0.6	-1.3	1.6	0.1	-1.0	-0.6
Diastolic blood pressure, automated reading	0.5	1.5	7.9	0.0	1.3	1.1	1.5	1.0	0.7	-1.3	1.4	-0.1	-0.0	2.8	-1.0	-0.9	1.4	0.7	-1.4	-1.0
Ever depressed for a whole week	0.1	0.1	0.4	-0.0	-0.3	-0.2	0.1	-0.1	0.0	0.2	-0.3	-0.4	-0.1	-0.4	0.2	-0.1	-0.3	-0.6	0.2	0.1
Unable to work because of sickness or disability	0.6	0.8	3.8	2.0	-0.1	-0.1	0.2	0.9	1.3	-0.8	0.9	-0.8	-0.8	-0.0	-0.8	-1.1	0.2	0.7	-0.7	-1.0
Commuting to job workplace: Cycle	2.1	2.6	9.1	-1.3	-1.8	-1.3	-2.0	-1.4	-1.6	1.4	-0.7	-1.3	1.4	-3.0	1.6	1.7	-1.4	-1.5	1.4	1.5
Myopia	0.2	0.3	0.9	-0.1	-0.6	0.7	-0.2	-0.1	-0.2	0.3	-0.8	-0.9	0.5	-0.4	0.3	0.6	-0.8	-0.4	0.5	0.3
Vascular/heart problems diagnosed by doctor	0.1	0.4	1.7	0.4	-0.3	0.2	-0.5	-0.1	-0.3	0.4	-1.1	1.3	0.0	-0.7	0.1	0.6	-1.0	-0.1	0.6	0.2
Cholesterol lowering medication	1.1	1.6	3.0	0.6	0.7	1.3	1.4	1.5	1.0	-1.6	1.7	0.8	-1.4	0.7	-1.3	-1.3	1.6	1.2	-1.3	-1.4
Medication: Omeprazole (e.g. Zanprol)	3.2	3.9	5.6	-1.2	-1.8	-1.9	-1.9	-2.1	-1.8	2.3	-2.4	-1.9	1.9	-1.5	2.0	2.2	-2.3	-1.9	2.1	2.1
Pain experienced in last month	0.1	0.2	0.7	0.6	0.5	0.2	0.1	0.2	0.6	-0.3	0.5	0.4	-0.0	-0.1	-0.2	-0.0	0.8	-0.1	-0.7	-0.2
Supplements: Calcium	2.8	3.1	4.5	1.6	1.9	1.5	1.4	2.0	1.7	-1.9	1.6	1.6	-1.8	1.9	-1.9	-2.1	1.4	1.6	-1.8	-2.0
Basal cell carcinoma (self-reported)	3.3	3.9	6.4	-2.3	-1.9	-1.6	-2.1	-2.0	-2.0	1.9	-1.9	-2.5	2.1	-1.2	2.0	2.0	-1.9	-1.7	2.1	2.0
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.8	0.7	0.2	0.7	0.2	0.5	0.7	-0.5	0.4	0.3	-0.3	1.7	-0.5	-0.4	0.8	0.4	-0.4	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	1.3	1.2	0.3	0.1	-0.3	0.0	0.5	0.1	-0.4	-0.1	-0.1	0.7	-0.1	-0.2	-0.3	0.2	0.0	0.0
Heart disease (siblings)	0.7	0.8	3.2	0.7	0.7	1.0	1.1	0.8	0.6	-0.9	0.9	0.4	-0.7	1.8	-0.7	-0.9	1.3	0.6	-0.9	-0.7
Alcohol drinker status: Previous	1.6	1.8	3.9	-0.9	-1.9	-1.4	-1.0	-1.4	-1.3	1.1	-0.3	-1.8	2.0	-1.5	1.5	1.1	-0.3	-1.8	1.2	1.3
Pack years of smoking	0.2	0.2	1.0	-0.5	-1.0	0.1	-0.1	-0.3	-0.4	-0.1	0.6	-0.7	0.8	-0.7	0.4	0.3	0.1	-0.3	0.3	0.3
Impedance of whole body	0.1	0.4	1.4	1.2	1.2	0.1	0.7	0.3	0.6	-0.1	-0.2	1.0	-0.7	1.1	-0.4	-0.5	0.3	0.7	-0.1	-0.2
Leg fat mass (left)	0.2	0.7	4.6	-0.3	-0.9	-0.1	-0.5	-0.6	-0.7	0.3	-0.3	-2.1	1.5	0.9	0.6	0.4	0.1	-0.9	0.4	0.5
Arm predicted mass (left)	0.0	0.2	0.6	-0.7	-0.1	0.5	0.4	0.2	-0.0	-0.5	0.7	-0.2	0.1	0.2	-0.2	0.1	0.8	0.1	-0.5	-0.2