TWAS hub - RARRES2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1300	0.0440	2.4e-04	0.025	NA	0.084	NA	0.047	3.9e-03	NA	2.2e-07	NA	9.6e-05
2	GTEx	Adipose Visceral Omentum	0.1270	0.0520	5.0e-03	0.069	NA	0.027	NA	0.051	1.9e-04	NA	1.5e-02	NA	1.2e-03
3	GTEx	Artery Aorta	0.1680	0.0600	1.5e-03	0.118	NA	0.066	NA	0.105	5.0e-07	NA	1.6e-04	NA	2.2e-06
4	GTEx	Artery Tibial	0.1432	0.0502	2.3e-04	0.020	NA	0.012	NA	0.021	1.0e-02	NA	3.5e-02	NA	7.7e-03
5	GTEx	Breast Mammary Tissue (Male)	0.0843	0.0769	1.7e-01	-0.013	NA	-0.011	NA	-0.007	8.7e-01	NA	6.7e-01	NA	5.0e-01
6	GTEx	Breast Mammary Tissue (Female)	0.0409	0.0856	3.5e-01	-0.007	NA	-0.010	NA	0.062	6.1e-01	NA	9.7e-01	NA	6.6e-03
7	GTEx	Cells Transformed fibroblasts	0.0830	0.0350	5.7e-03	0.088	NA	0.063	NA	0.077	3.8e-07	NA	1.7e-05	NA	2.2e-06
8	GTEx	Nerve Tibial	0.2319	0.0510	6.7e-09	0.180	NA	0.188	NA	0.182	8.8e-13	NA	2.6e-13	NA	6.3e-13
9	GTEx	Pancreas	0.2050	0.0780	5.4e-03	0.113	NA	0.148	NA	0.120	1.7e-05	NA	8.0e-07	NA	9.4e-06
10	GTEx	Skin Sun Exposed Lower leg	0.2000	0.0570	1.1e-05	0.034	NA	0.030	NA	0.035	8.2e-04	NA	1.4e-03	NA	6.5e-04
11	METSIM	Adipose	0.0635	0.0243	2.9e-04	0.029	0.035	0.024	0.033	0.026	3.1e-05	4.2e-06	1.2e-04	8.2e-06	7.8e-05
12	TCGA	Breast Invasive Carcinoma	0.0177	0.0084	1.9e-07	0.038	0.036	0.033	NA	0.033	2.6e-08	5.7e-08	1.9e-07	NA	1.9e-07
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0226	0.0129	6.3e-04	0.032	0.028	0.032	NA	0.026	1.5e-04	3.7e-04	1.5e-04	NA	5.5e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	6	7	8	9	10	11	12	13
Age at last live birth	7.5	10.9	15.9	-2.8	-3.8	-3.5	-3.2	-2.8	-3.5	-3.9	3.4	-4.0	-2.4	-3.7	-3.6
Impedance of leg (right)	6.2	29.9	43.8	4.1	6.1	6.0	6.6	4.7	6.1	6.3	-3.7	6.1	4.8	6.4	6.3
Impedance of leg (left)	6.0	29.1	39.9	4.6	6.2	5.8	6.3	4.7	5.9	6.3	-3.9	6.2	4.3	6.3	6.1
Body Mass Index (BMI) (2010)	5.0	6.8	11.0	-2.2	-3.1	-2.9	-3.0	-3.3	-2.9	-3.0	1.9	-1.8	-2.0	-3.0	-2.8
Ever unenthusiastic/disinterested for a whole week	5.0	6.1	14.7	3.8	2.9	3.0	2.2	2.6	2.9	2.6	-1.3	1.8	0.9	2.8	2.6
Blood clot in the leg (DVT)	4.8	6.2	11.6	-3.1	-2.7	-2.4	-2.6	-2.0	-2.4	-2.8	3.4	-2.2	-1.8	-2.7	-2.6
Deep venous thrombosis (DVT) (self-reported)	4.7	6.1	10.8	-2.9	-2.8	-2.3	-2.5	-1.7	-2.5	-2.8	3.3	-2.3	-1.8	-2.7	-2.7
Bipolar Disorder (2018)	4.3	6.8	10.3	-2.4	-2.8	-3.2	-3.0	-2.3	-3.1	-3.2	2.6	0.0	-2.3	-3.0	-2.9
Ever depressed for a whole week	4.3	5.3	12.7	3.6	2.6	2.7	2.1	2.1	2.6	2.2	-2.1	2.4	0.7	2.3	2.4
Impedance of whole body	4.2	21.3	33.7	4.8	5.2	4.9	5.8	3.7	5.0	5.3	-2.8	4.9	3.7	5.4	5.2
Age at first live birth	4.1	7.3	12.4	-2.2	-2.7	-3.0	-2.8	-2.4	-3.0	-3.0	2.3	-3.5	-3.0	-3.0	-2.9
Friendships satisfaction	4.0	5.0	9.1	-1.5	-2.5	-2.2	-1.9	-3.0	-2.3	-2.6	1.8	-1.9	-2.6	-2.5	-2.5
Family relationship satisfaction	3.6	4.4	7.9	-2.2	-2.2	-2.3	-2.3	-2.1	-2.3	-2.2	2.8	-1.5	-1.4	-2.4	-2.3
Breastfed as a baby	3.3	4.1	8.9	-3.0	-2.0	-1.9	-1.8	-2.3	-1.9	-2.1	1.8	-2.3	-1.7	-2.2	-1.8
Major Depression (MDD)	3.1	3.8	8.5	2.0	2.1	2.1	2.3	2.1	2.1	2.0	-1.1	2.9	0.7	2.0	2.1
Townsend deprivation index at recruitment	3.1	4.3	7.8	0.5	2.0	2.4	2.2	2.5	2.4	2.3	-2.8	0.9	1.8	2.6	2.3
Age when periods started (menarche)	3.1	7.5	13.2	2.7	2.8	3.0	3.6	2.4	3.0	3.0	-3.0	2.3	2.4	2.7	2.9
Ulcerative Colitis	2.9	4.1	7.8	-0.5	-2.2	-2.5	-1.7	-2.8	-2.5	-2.6	2.0	-1.3	-1.0	-2.3	-2.5
Medication: Blood pressure	2.9	5.6	8.5	-2.3	-2.7	-2.5	-2.6	-2.9	-2.5	-2.3	2.9	-1.7	-2.0	-2.6	-2.3
Serious illness, injury or assault to yourself	2.7	3.3	5.6	2.4	1.7	2.2	2.1	1.0	2.2	1.8	-1.7	1.5	1.6	1.9	2.3
Happiness	2.7	3.3	5.1	-1.0	-1.7	-1.9	-2.2	-2.1	-2.0	-1.7	2.1	-1.7	-1.5	-2.1	-2.1
Mouth/teeth dental problems: Bleeding gums	2.7	3.5	7.4	-0.6	-2.0	-2.5	-2.1	-0.9	-2.4	-1.8	1.9	-0.8	-2.7	-2.2	-2.0
Eye problems/disorders: Glaucoma	2.6	3.1	8.1	1.2	1.7	1.6	1.5	2.4	1.6	1.8	-2.2	2.9	0.4	1.9	1.7
Medication: Bendroflumethiazide	2.6	3.9	8.6	-2.9	-2.1	-2.2	-2.3	-1.4	-2.2	-1.8	2.1	-1.4	-1.7	-2.0	-2.0
Diabetes (father)	2.5	3.1	4.9	2.0	2.0	2.2	1.7	0.6	2.2	1.6	-0.9	1.7	2.2	1.9	2.1
Hair/balding pattern: Pattern 3	2.5	3.7	7.3	-1.2	-2.2	-2.0	-1.8	-1.3	-2.1	-2.4	2.0	-2.7	-0.8	-2.3	-2.2
Blood Platelet Count	2.4	27.8	37.8	3.8	6.0	5.8	4.7	5.6	5.9	6.1	-5.3	4.7	5.3	6.2	6.1
Heart disease (mother)	2.4	3.0	6.3	0.4	1.9	1.9	1.9	0.7	2.0	1.9	-1.1	2.5	2.4	1.5	1.8
Heart attack	2.3	3.0	5.1	1.7	2.2	1.7	1.4	1.8	1.8	2.3	-0.2	0.9	2.2	2.1	2.1
Impedance of arm (left)	2.2	10.3	19.6	3.8	3.5	3.4	4.4	2.3	3.4	3.8	-1.4	3.0	2.8	3.6	3.5
Commuting to job workplace: Cycle	2.2	2.7	4.4	-1.1	-1.7	-1.9	-1.4	-1.7	-1.8	-1.8	0.8	-1.7	-2.1	-2.1	-1.9
Cardiovascular Disease	2.1	6.9	10.8	-3.3	-2.7	-2.8	-3.2	-2.2	-2.8	-2.3	3.0	-2.0	-2.2	-3.2	-2.6
Medication: Ibuprofen (e.g. Nurofen)	2.1	2.7	4.2	-0.6	-1.5	-1.8	-1.9	-1.8	-1.8	-1.8	2.0	0.0	-1.8	-2.0	-1.9
Leg predicted mass (right)	2.1	11.1	19.0	-3.4	-3.4	-3.5	-4.4	-3.0	-3.6	-3.6	1.2	-3.4	-3.6	-3.9	-3.7
Leg fat-free mass (right)	2.0	10.9	18.9	-3.3	-3.4	-3.4	-4.3	-2.9	-3.5	-3.6	1.2	-3.4	-3.6	-3.9	-3.7
Average weekly red wine intake	2.0	2.9	5.0	-1.3	-1.6	-2.2	-2.2	-2.1	-2.1	-1.5	1.9	-0.9	-1.4	-1.9	-1.8
Average weekly champagne plus white wine intake	2.0	2.8	5.9	-0.9	-2.1	-1.7	-1.4	-2.0	-1.7	-2.0	2.4	-1.5	-0.7	-2.0	-1.8
Qualifications: None of the above	1.9	4.2	7.7	1.0	1.8	2.5	2.8	0.8	2.5	2.4	-1.8	2.3	1.6	2.5	2.6
Heart attack/myocardial infarction (self-reported)	1.9	2.4	4.2	1.4	1.9	1.5	1.2	1.8	1.6	2.1	-0.0	0.8	1.9	1.9	2.0
Primary Biliary Cirrhosis	1.8	2.6	6.4	-1.8	-1.7	-1.5	-0.9	-2.5	-1.4	-1.6	2.4	-1.6	-0.8	-1.6	-1.3
Rheumatoid Arthritis	1.8	2.5	5.0	1.2	1.9	1.7	1.9	1.1	1.7	1.8	-2.2	0.0	1.7	1.8	1.6
Leg fat-free mass (left)	1.8	9.7	16.4	-3.5	-3.2	-3.1	-4.0	-2.9	-3.2	-3.3	1.2	-3.3	-3.2	-3.6	-3.4
Leg predicted mass (left)	1.8	9.6	16.6	-3.4	-3.2	-3.1	-4.1	-2.9	-3.2	-3.3	1.2	-3.3	-3.1	-3.6	-3.4
Time employed in main current job	1.8	2.1	3.6	1.0	1.6	1.6	1.2	1.9	1.5	1.5	-1.3	1.5	1.9	1.8	1.2
Neck or shoulder pain in last month	1.8	2.5	4.4	0.3	2.1	2.0	1.7	1.0	2.0	2.0	-0.5	1.1	1.6	2.1	1.9
Ever had hysterectomy (womb removed)	1.7	2.0	7.8	2.8	1.5	1.3	1.5	0.8	1.3	1.7	0.2	1.5	0.4	1.4	1.3
Pain all over the body in last month	1.7	1.8	4.2	1.4	1.0	1.2	1.7	2.0	1.4	1.3	-0.3	1.3	1.6	1.4	1.6
Impedance of arm (right)	1.7	8.0	14.6	3.6	3.1	2.9	3.8	2.0	2.9	3.4	-1.0	2.8	2.5	3.2	3.2
Frequency of tiredness / lethargy in last 2 weeks	1.7	2.7	5.3	0.4	2.3	2.1	1.6	1.3	2.1	1.9	-1.6	0.7	1.1	2.0	2.2
High blood pressure (siblings)	1.7	2.5	7.9	-2.8	-1.7	-1.7	-1.5	-1.5	-1.7	-1.2	1.5	-1.6	-0.5	-1.7	-1.4
Whole body fat-free mass	1.7	9.9	18.7	-3.7	-3.1	-3.2	-4.3	-2.6	-3.3	-3.5	0.6	-3.1	-3.4	-3.6	-3.5
Whole body water mass	1.7	9.9	18.8	-3.8	-3.1	-3.1	-4.3	-2.6	-3.2	-3.5	0.7	-3.1	-3.4	-3.6	-3.5
Trunk fat-free mass	1.6	9.2	18.3	-3.7	-3.0	-3.0	-4.3	-2.3	-3.1	-3.4	0.3	-3.0	-3.2	-3.5	-3.4
Noisy workplace	1.6	2.0	3.3	1.0	1.5	1.6	1.5	0.5	1.7	1.6	-1.7	1.8	0.9	1.6	1.6
Trunk predicted mass	1.6	8.9	17.6	-3.6	-2.9	-3.0	-4.2	-2.3	-3.1	-3.4	0.3	-3.0	-3.2	-3.4	-3.3
Illnesses of father: Heart disease	1.6	2.2	5.8	-1.1	-1.6	-1.4	-2.2	-1.3	-1.4	-1.4	1.6	-2.4	-1.0	-1.4	-1.3
Mouth/teeth dental problems: Mouth ulcers	1.6	2.5	4.8	1.5	1.8	1.7	1.2	2.1	1.7	1.7	-1.0	2.2	1.4	1.6	1.5
High cholesterol (Self-reported)	1.6	2.8	4.5	-1.9	-1.5	-2.0	-1.8	-1.2	-2.0	-1.6	1.6	-1.5	-2.1	-1.9	-1.6
Systolic Blood Pressure	1.5	7.7	16.8	-4.1	-2.9	-2.8	-3.2	-3.4	-2.8	-2.5	3.1	-1.7	-0.2	-3.3	-2.9
Qualifications: A levels/AS levels or equivalent	1.5	3.4	7.0	-1.5	-1.9	-2.1	-2.3	-1.1	-2.1	-2.1	0.7	-2.3	-0.5	-2.6	-2.3
Wheeze or whistling in the chest in last year	1.5	2.6	3.5	-1.7	-1.9	-1.5	-1.6	-1.8	-1.5	-1.7	1.9	-1.5	-1.6	-1.8	-1.7
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	3.0	-1.6	-1.3	-1.6	-1.7	-0.9	-1.7	-1.4	1.3	-1.3	-0.4	-1.3	-1.7
Qualifications: nursing, teaching	1.5	2.3	4.6	-0.6	-1.3	-1.8	-2.1	-0.7	-1.8	-1.7	0.8	-1.4	-1.7	-2.1	-2.1
Medication for cholesterol	1.5	2.3	6.1	0.6	1.6	1.4	1.4	2.3	1.4	1.0	-2.5	1.1	2.0	1.3	1.2
Wears glasses or contact lenses	1.5	1.8	3.5	1.7	1.0	1.0	1.2	1.8	1.1	0.8	-1.9	1.7	1.0	1.6	1.1
Age at First Birth	1.4	2.0	3.8	-0.3	-1.4	-1.9	-1.6	-1.4	-1.9	-1.6	1.2	-0.2	-1.3	-1.7	-1.9
Lupus	1.4	2.1	5.1	1.0	1.3	2.0	2.3	1.0	2.0	1.3	-1.1	1.0	1.3	1.5	1.6
Bilateral oophorectomy (both ovaries removed)	1.4	1.7	5.4	1.2	1.4	1.2	1.4	0.7	1.2	1.3	-0.2	2.3	0.4	1.8	1.5
Supplements: Glucosamine	1.4	1.8	3.0	0.2	1.7	1.7	1.6	1.6	1.7	1.5	-1.1	0.9	0.6	1.5	1.5
Financial difficulties in last 2 years	1.4	1.9	3.6	0.8	1.7	1.9	1.6	1.1	1.9	1.4	-0.2	1.5	1.1	1.7	1.5
Chest pain or discomfort	1.4	2.1	4.2	0.6	1.2	1.7	1.3	1.2	1.8	1.5	-1.7	2.1	0.9	1.5	1.8
Bipolar Disorder (2011)	1.3	1.3	3.0	-1.2	-1.4	-1.5	-1.7	-0.6	-1.6	-1.7	1.0	0.0	-1.2	0.0	0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	3.8	0.8	1.7	1.6	1.2	1.1	1.6	1.7	-1.2	1.9	-0.6	1.0	1.2
High blood pressure	1.3	3.7	15.2	-3.9	-1.8	-1.7	-2.3	-2.1	-1.7	-1.4	2.1	-0.9	-0.5	-2.0	-1.5
Number of incorrect matches in round	1.3	2.2	6.4	-1.6	-1.7	-1.8	-1.5	-0.3	-1.8	-1.5	0.9	-0.6	-2.5	-1.3	-1.5
Comparative body size at age 10	1.3	3.6	5.2	-0.2	-1.8	-2.2	-2.3	-1.6	-2.2	-2.2	1.7	-2.2	-2.0	-2.1	-2.3
Basal metabolic rate	1.3	7.1	14.2	-3.3	-2.6	-2.7	-3.8	-2.1	-2.7	-2.8	0.3	-2.7	-2.9	-3.0	-2.9
Cholesterol lowering medication	1.3	2.0	5.9	-1.2	-1.3	-1.1	-0.9	-2.4	-1.1	-0.8	2.2	-1.7	-1.5	-1.2	-1.0
Breast Cancer	1.2	2.9	4.9	-1.9	-2.0	-2.0	-2.2	-1.5	-2.0	-2.0	0.6	-0.6	-1.0	-2.2	-2.0
Ovarian Cancer	1.2	1.6	4.0	2.0	1.7	1.3	0.9	1.2	1.3	1.4	-0.5	1.3	1.5	1.1	1.0
Systolic blood pressure, automated reading	1.2	3.5	13.3	-3.6	-1.9	-1.9	-1.9	-1.9	-1.8	-1.6	1.6	-0.7	1.6	-1.8	-1.6
Fed-up feelings	1.2	2.2	4.9	-1.9	-1.4	-1.4	-2.2	-0.2	-1.4	-1.3	0.7	-2.2	-1.8	-1.5	-1.4
Past tobacco smoking	1.2	2.3	4.9	0.1	1.5	1.7	1.8	1.3	1.7	1.6	-0.9	1.7	2.2	1.4	1.8
Arm fat-free mass (right)	1.2	6.0	11.8	-3.4	-2.3	-2.4	-3.4	-1.8	-2.5	-2.6	-0.1	-2.2	-2.8	-2.8	-2.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	2.8	1.7	1.2	1.0	0.6	1.2	1.0	1.3	-1.3	1.3	1.7	1.2	1.1
Ever smoked	1.2	2.2	5.7	-0.0	-1.5	-1.7	-1.8	-1.0	-1.6	-1.6	0.8	-1.6	-2.4	-1.4	-1.7
Arm fat-free mass (left)	1.2	6.1	12.2	-3.4	-2.4	-2.5	-3.5	-1.9	-2.5	-2.6	-0.0	-2.5	-2.7	-2.7	-2.6
Ever had prostate specific antigen (PSA) test	1.2	1.4	2.4	-0.8	-1.3	-1.4	-1.5	-1.1	-1.5	-1.4	0.7	-0.9	-1.0	-1.4	-1.4
Alzheimer’s Disease (in mother)	1.1	1.3	7.9	0.1	0.5	1.1	1.4	0.1	1.1	1.0	0.1	-0.1	2.8	1.1	1.5
Ulcerative Colitis (UC)	1.1	2.0	4.2	0.6	-1.4	-1.7	-1.1	-1.8	-1.8	-2.1	1.5	-0.2	-1.1	-1.6	-1.8
Verbal and Numeric Reasoning (VNR)	1.1	2.6	6.9	-0.8	-1.4	-2.0	-1.9	-1.1	-1.9	-1.7	1.1	-2.6	-0.3	-2.1	-1.8
Coronary Artery Disease (CAD)	1.1	1.3	3.9	0.8	0.7	0.9	1.5	0.7	1.1	1.0	0.3	2.0	1.8	1.0	1.2
Medication: Simvastatin	1.1	1.6	3.1	-1.7	-1.0	-1.3	-1.3	-1.5	-1.3	-1.0	1.2	-1.6	-1.0	-1.5	-1.2
Glaucoma (self-reported)	1.1	1.2	3.4	0.4	1.0	0.7	0.8	1.7	0.8	1.1	-1.8	1.8	0.2	1.2	1.1
Arm predicted mass (right)	1.1	5.6	11.6	-3.4	-2.3	-2.2	-3.3	-1.9	-2.3	-2.6	-0.1	-2.2	-2.8	-2.7	-2.5
Leg pain on walking	1.1	1.4	4.5	0.6	1.3	1.4	0.9	1.4	1.4	1.2	-1.3	2.1	0.2	1.3	1.0
Smoking status: Previous	1.1	1.6	3.0	-0.3	-1.2	-1.4	-1.3	-1.4	-1.4	-1.4	1.0	-1.7	-1.5	-1.2	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	3.5	-1.9	-0.9	-1.0	-1.4	0.8	-1.0	-0.8	1.1	-1.1	-1.3	-1.0	-0.9
Depression (Nagel 2018)	1.0	1.6	2.8	1.3	1.7	1.6	1.4	0.8	1.6	1.6	-0.2	1.7	-0.8	1.0	1.0
Crohns Disease (2012)	1.0	1.6	4.1	-0.5	-1.4	-1.4	-2.0	-0.3	-1.4	-1.6	1.2	-0.9	-1.4	-1.3	-1.4
Fasting Glucose	1.0	1.2	2.9	-1.0	-1.1	-1.1	-1.7	-0.8	-1.0	-1.4	1.6	-0.7	-0.7	-0.9	-1.3
Hayfever, allergic rhinitis or eczema	1.0	2.3	8.2	0.2	-1.0	-1.4	-1.2	-1.7	-1.4	-1.4	1.4	-1.8	-2.9	-1.5	-1.6
Birth weight of first child	1.0	1.9	3.0	-1.1	-1.5	-1.5	-1.3	-1.1	-1.6	-1.6	1.2	-1.1	-1.7	-1.5	-1.7
Qualifications: College or University degree	1.0	3.1	7.5	0.5	-1.7	-1.9	-1.9	-0.1	-2.0	-2.2	1.0	-2.7	-1.2	-2.3	-2.3
Knee pain experienced in last month	1.0	1.6	3.2	-0.2	1.3	1.7	1.8	0.4	1.7	1.4	-1.6	0.9	0.4	1.3	1.7
Hypertension (Self-reported)	1.0	2.6	12.4	-3.5	-1.5	-1.5	-1.9	-1.9	-1.4	-1.1	1.5	-0.3	-0.5	-1.8	-1.2
Commuting to job workplace: Walk	1.0	1.1	2.2	1.5	1.3	1.0	1.1	1.4	1.1	1.3	0.3	0.1	0.8	1.3	1.0
Medication: Gliclazide	1.0	1.2	2.2	0.8	1.2	1.4	1.5	1.0	1.4	1.3	-0.5	0.9	1.0	1.1	1.0
Mean Putamen Volume	0.9	1.0	2.8	0.4	1.2	0.9	1.2	0.5	0.9	1.0	0.6	1.0	1.7	1.2	1.1
BMI	0.9	5.4	11.8	-3.4	-2.5	-2.4	-2.9	-2.1	-2.4	-2.3	1.8	-2.0	-1.9	-2.5	-2.4
Chronotype (morning person)	0.9	2.0	4.8	-2.2	-1.6	-1.2	-1.7	-1.5	-1.3	-1.9	0.5	-0.8	-0.5	-1.7	-1.5
Frequency of depressed mood in last 2 weeks	0.9	1.3	2.4	1.1	1.3	1.3	1.0	0.9	1.4	1.5	-0.1	1.5	-1.4	0.9	1.2
Stomach or abdominal pain in last month	0.9	1.1	5.3	0.3	1.3	0.9	0.6	0.8	0.9	1.0	-2.3	1.1	0.4	1.0	0.9
Illnesses of siblings	0.9	1.2	5.3	2.3	1.1	1.1	1.0	1.8	1.0	0.7	-0.9	0.9	0.4	1.0	0.5
Eye problems/disorders: None of the above	0.9	1.0	3.4	-0.2	-0.8	-0.9	-0.7	-1.8	-1.0	-0.9	0.5	-1.5	-0.1	-1.3	-1.3
Myopia	0.9	1.3	3.9	0.2	-1.3	-1.3	-1.0	-0.8	-1.3	-1.1	0.0	-1.4	-2.0	-1.4	-1.3
Vascular/heart problems diagnosed by doctor	0.9	2.4	9.2	3.0	1.3	1.4	1.9	1.9	1.3	1.0	-2.1	0.6	0.0	1.6	1.1
Arm predicted mass (left)	0.9	4.8	10.4	-3.2	-2.0	-2.1	-3.2	-1.5	-2.2	-2.2	-0.1	-2.2	-2.4	-2.3	-2.2
Ever used hormone-replacement therapy (HRT)	0.8	1.1	2.0	0.4	1.3	1.0	1.4	0.3	1.0	1.3	-0.7	1.2	0.7	1.4	1.2
Angina	0.8	1.0	1.8	0.5	1.1	1.2	1.3	0.1	1.3	1.3	-0.6	1.2	0.2	1.2	1.3
Medication: Lansoprazole	0.8	1.0	1.5	1.1	1.2	1.2	1.0	0.5	1.1	1.2	-0.7	0.7	1.2	1.1	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.3	2.6	0.9	1.1	1.0	1.2	1.6	1.1	1.1	-0.1	1.4	1.2	1.3	1.4
Pulse wave peak to peak time	0.8	0.9	5.4	-0.5	-0.6	-0.8	-0.8	-1.1	-0.9	-0.6	0.4	0.4	-2.3	-1.0	-0.8
Angina (self-reported)	0.8	1.1	2.0	0.6	1.1	1.3	1.3	0.1	1.3	1.3	-0.5	1.4	0.2	1.3	1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	2.7	0.7	1.6	1.4	1.7	1.1	1.4	1.5	-1.7	1.0	1.1	1.6	1.5
Commuting to job workplace: Public transport	0.8	1.0	3.6	-0.8	-0.8	-1.0	-0.7	-1.1	-1.0	-0.9	0.6	-1.9	-1.0	-1.1	-1.1
Depressed Affect (Nagel 2018)	0.7	1.5	2.6	-1.2	-1.3	-1.4	-1.6	-0.5	-1.3	-1.2	1.4	-1.2	-1.4	-1.3	-1.4
Hypothyroidism (self reported)	0.7	1.5	3.2	-1.8	-1.4	-1.2	-1.3	-1.3	-1.3	-1.4	0.6	-1.2	-1.0	-1.4	-1.3
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	3.8	1.0	1.1	0.9	0.6	0.6	0.9	0.9	-2.0	0.8	0.2	1.0	1.0
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	1.4	1.0	1.0	1.1	1.2	0.6	1.1	1.0	0.3	-0.2	0.8	1.1	1.2
Fluid intelligence score	0.7	1.4	3.7	-0.4	-1.0	-1.4	-1.6	-0.9	-1.4	-1.1	0.3	-1.9	-0.7	-1.6	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.9	-1.0	-0.6	-1.1	-1.4	0.3	-1.0	-0.8	-0.2	-0.9	-1.2	-1.0	-1.0
Pulse wave Arterial Stiffness index	0.7	0.8	4.8	0.5	0.6	0.7	0.5	1.1	0.7	0.5	-0.5	-0.5	2.2	0.9	0.7
Ever highly irritable/argumentative for 2 days	0.7	0.9	2.1	1.4	0.5	1.0	0.7	0.2	1.0	0.8	-0.9	1.0	-1.3	1.0	1.1
Leg fat percentage (right)	0.7	2.6	4.9	0.1	1.7	1.6	1.5	1.2	1.7	2.2	-1.2	2.1	1.7	1.9	2.1
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	1.4	0.4	0.7	0.8	1.2	1.1	0.9	1.2	-1.2	0.9	-0.3	0.8	1.0
Shortness of breath walking on level ground	0.7	0.8	2.0	1.4	0.7	0.6	0.8	0.9	0.6	0.8	-1.3	1.4	-0.2	0.7	0.8
Guilty feelings	0.7	1.1	7.2	-1.0	-0.7	-0.9	-1.0	-0.7	-0.9	-1.0	-0.0	-0.0	-2.7	-1.0	-0.8
Leg fat percentage (left)	0.7	2.5	5.4	0.4	1.7	1.4	1.3	1.1	1.6	2.3	-1.2	2.3	1.6	1.8	2.0
Diastolic blood pressure, automated reading	0.7	2.0	7.7	-2.8	-1.3	-1.5	-1.9	-1.1	-1.5	-1.1	0.8	-0.8	1.4	-1.2	-1.3
Bipolar Disorder or Schizophrenia	0.6	1.4	3.3	0.4	-1.2	-1.5	-1.4	-0.6	-1.5	-1.8	1.2	0.0	-0.9	-1.4	-1.4
Allergy or Eczema	0.6	1.7	11.0	0.8	-0.6	-1.0	-0.9	-1.1	-1.0	-1.0	0.9	-1.1	-3.3	-1.2	-1.2
Hand grip strength (left)	0.6	1.6	6.5	-1.6	1.5	1.1	0.2	1.8	1.1	1.0	-2.5	-0.2	-0.5	1.0	1.0
Relative age of first facial hair	0.6	1.2	3.8	-0.5	-0.7	-1.3	-1.2	-0.6	-1.2	-0.8	1.0	-0.4	-1.9	-1.6	-1.3
Relative age voice broke	0.6	1.0	4.4	-2.1	-0.4	-0.8	-1.2	-0.6	-0.7	-0.3	0.8	-0.2	-1.7	-1.0	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	3.1	1.8	1.0	1.0	0.9	0.7	1.1	1.0	-0.1	1.7	1.4	1.3	1.3
Sitting height	0.6	4.0	13.8	-3.7	-1.4	-1.7	-2.6	-1.2	-1.8	-2.0	-1.0	-1.9	-2.4	-1.8	-1.9
Mouth/teeth dental problems: Dentures	0.6	1.0	3.3	-1.2	-0.8	-0.7	-0.8	-1.8	-0.7	-0.9	1.5	-1.4	0.3	-1.0	-0.8
Asthma	0.6	1.2	5.8	0.3	0.9	0.9	1.4	1.6	0.9	0.6	-2.4	-0.2	-0.7	0.9	0.9
Medication for pain relief, constipation, heartburn	0.6	1.0	2.4	0.5	0.7	1.2	1.5	1.3	1.1	0.7	-1.5	-0.7	0.5	0.9	1.0
Medication: Seretide 50 evohaler	0.6	0.7	1.7	-0.3	-0.7	-0.9	-1.0	0.6	-0.8	-1.0	0.3	-1.3	-1.1	-0.8	-0.8
Overall health rating	0.6	1.3	2.7	0.3	1.3	1.1	0.9	0.3	1.2	1.6	-0.6	1.5	1.0	1.4	1.6
Ever had bowel cancer screening	0.6	0.7	3.3	-0.7	0.6	0.6	0.9	0.2	0.6	0.6	-0.3	0.6	1.8	0.9	1.1
Alcohol drinker status: Never	0.6	0.7	5.8	-1.1	0.7	0.5	0.0	-0.0	0.5	0.8	0.5	0.1	2.4	0.1	0.3
Alzheimer’s Disease (including proxy)	0.5	0.7	2.6	-1.6	-0.5	0.4	0.2	0.1	0.5	-0.0	1.0	-1.4	1.4	0.3	0.5
Respiratory disease	0.5	1.1	2.4	0.2	1.0	1.3	1.4	1.3	1.3	1.0	-1.6	-0.0	-0.5	1.2	1.2
Medication: Co-codamol	0.5	0.6	1.0	0.0	0.6	1.0	0.9	0.8	1.0	1.0	-0.3	0.9	0.2	0.9	1.0
Diabetes (mother)	0.5	0.7	2.6	0.9	1.0	0.5	0.9	1.6	0.6	0.6	-1.4	-0.1	0.5	0.5	0.6
Average weekly fortified wine intake	0.5	0.6	1.3	-0.9	-0.9	-0.8	-0.8	-1.1	-0.8	-0.8	1.0	-0.8	-0.1	-0.8	-0.6
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	1.3	-0.8	-0.8	-1.1	-0.4	0.5	-1.1	-1.0	-0.5	-0.9	-0.1	-0.6	-0.7
Weight	0.5	2.2	5.4	-2.2	-1.4	-1.5	-2.3	-1.0	-1.5	-1.3	-0.2	-1.4	-1.6	-1.6	-1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	6.5	0.4	1.6	1.3	0.8	2.0	1.2	1.0	-2.5	-0.3	0.8	1.4	1.0
Loud music exposure frequency	0.5	0.5	2.7	0.4	0.9	0.1	-0.0	1.3	0.1	0.3	-1.6	-0.4	-1.0	0.3	-0.0
Medication: Ibuprofen	0.5	0.6	1.1	0.6	-0.3	-0.7	-0.8	-1.0	-0.7	-0.7	1.0	0.9	-0.8	-0.9	-0.9
Illnesses of father: None of the above (group 1)	0.5	0.6	2.8	0.7	-0.7	-0.9	-0.4	0.4	-0.9	-0.7	-0.2	0.3	-1.7	-0.6	-0.9
Hearing aid user	0.5	0.6	1.5	0.2	0.6	0.5	0.7	0.3	0.6	0.6	-1.1	0.7	1.2	1.0	1.0
Tinnitus: Yes, now most or all of the time	0.5	0.5	2.6	-0.2	1.0	0.6	0.2	1.6	0.5	0.4	-1.2	0.1	-0.9	0.5	0.3
Illnesses of father: High blood pressure	0.5	0.6	1.5	0.5	-0.9	-0.5	-1.0	-1.1	-0.6	-0.8	0.3	-0.8	-0.2	-1.2	-0.9
Fractured/broken bones in last 5 years	0.5	0.6	1.2	1.0	0.8	1.0	0.8	0.5	1.1	1.1	-0.3	0.0	0.7	0.9	1.0
Supplements: Calcium	0.5	0.6	4.0	-2.0	-0.2	0.2	0.4	-0.9	0.3	0.1	1.0	0.5	0.8	-0.2	0.3
Schizophrenia (2018)	0.4	0.8	6.0	2.4	0.7	0.7	0.7	1.0	0.6	0.2	-0.6	0.0	0.7	0.7	0.5
Alzheimer’s Disease (in father)	0.4	0.4	2.2	-1.5	0.5	0.2	-0.0	1.3	0.2	0.2	-0.7	-0.7	-0.1	0.5	-0.0
Irritable Bowel Disease (IBD)	0.4	1.0	3.1	0.1	-1.0	-1.1	-1.1	-0.8	-1.2	-1.8	0.6	-0.8	-0.8	-1.0	-1.2
LDL Cholesterol	0.4	0.6	1.0	0.5	-0.8	-0.7	-0.6	-1.0	-0.7	-0.8	0.8	-0.6	-1.0	-0.8	-0.8
Blood Eosinophil Count	0.4	2.9	10.4	-1.9	-1.6	-1.5	-1.7	-0.3	-1.5	-1.3	1.7	-2.2	-3.2	-1.4	-1.4
Type 2 Diabetes (T2D) (2018)	0.4	0.7	5.2	-0.1	-0.4	-0.4	-0.8	-0.1	-0.5	-0.9	0.4	-2.3	-0.9	-0.6	-1.0
Neuroticism	0.4	0.9	3.0	-0.8	-1.0	-0.7	-1.0	-1.0	-0.7	-0.9	1.7	-0.9	-1.1	-0.8	-0.8
Supplements: Zinc	0.4	0.4	1.7	0.4	0.4	1.0	0.9	1.3	0.9	0.2	-0.1	0.1	0.3	0.6	0.6
Medication: Metformin	0.4	0.5	5.9	-0.1	-0.4	-0.2	-0.0	0.2	-0.3	-0.6	0.3	-2.4	0.2	-0.3	-0.4
Severe depression (siblings)	0.4	0.4	2.0	-0.2	0.6	0.7	0.3	-0.1	0.7	0.8	0.1	1.4	0.7	0.7	0.7
Pack years adult smoking proportion	0.4	0.6	3.8	-0.6	-0.6	-0.5	-0.3	-1.0	-0.5	-0.6	1.9	0.3	-0.1	-0.7	-0.6
Trunk fat percentage	0.4	1.7	3.8	0.6	1.5	1.1	1.2	0.8	1.3	2.0	-1.2	1.7	1.1	1.5	1.7
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	1.3	-0.3	-0.8	-0.9	-1.1	-0.4	-0.8	-0.6	0.9	-0.3	0.5	-0.7	-0.6
Chronic bronchitis/emphysema (father)	0.4	0.4	3.0	-1.7	-0.5	-0.3	0.0	-0.6	-0.4	-0.5	0.6	-0.7	0.8	-0.5	-0.2
Body mass index (BMI)	0.4	1.7	3.6	-1.7	-1.5	-1.5	-1.9	-1.2	-1.4	-1.1	0.6	-1.3	-1.0	-1.5	-1.2
Alcohol usually taken with meals	0.4	0.6	1.3	-0.8	-0.8	-1.2	-0.7	-0.2	-1.1	-0.6	0.9	-0.6	-1.0	-0.7	-0.9
Neuroticism score	0.4	0.8	1.9	-1.4	-1.0	-0.6	-1.0	-0.7	-0.6	-0.8	0.9	-1.2	-1.3	-0.9	-0.6
Alcohol intake versus 10 years previously	0.4	0.6	4.0	-2.0	-0.5	-0.1	0.1	-0.2	-0.1	-0.5	-0.1	0.6	-1.6	-0.4	-0.2
Peak expiratory flow (PEF)	0.4	0.9	2.8	-1.1	-0.1	-0.9	-1.2	0.2	-1.0	-0.7	-1.2	-1.7	-0.9	-0.5	-1.0
Gout (self-reported)	0.4	0.5	1.5	0.8	0.8	0.8	1.2	-0.3	0.7	1.0	0.2	0.5	0.3	1.1	0.8
Medication: Amlodipine	0.4	0.6	1.4	-1.2	-1.0	-0.8	-1.0	-0.7	-0.8	-1.1	0.2	0.0	-0.0	-0.8	-0.8
Birth weight	0.4	0.9	2.4	-0.5	-0.8	-1.0	-0.6	-1.0	-1.1	-1.3	0.7	0.1	-1.5	-1.2	-1.1
Number of full brothers	0.4	0.6	1.9	-1.4	-0.4	-0.8	-1.0	-0.7	-0.7	-0.6	0.9	-0.4	-0.5	-0.8	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.4	-0.3	-0.6	-1.0	-0.9	0.7	-1.1	-0.9	0.3	0.3	-1.2	-0.5	-0.8
Medication: Blood pressure	0.4	0.8	3.5	-1.9	-0.6	-1.1	-1.2	-0.7	-1.0	-0.5	0.4	-0.4	-0.2	-0.9	-0.7
Medication: Allopurinol	0.4	0.6	1.6	1.3	0.5	0.7	1.0	0.2	0.7	0.8	0.1	-0.3	0.6	1.2	0.9
Mean time to correctly identify matches	0.4	0.8	3.2	-1.2	-0.9	-0.4	-0.3	-1.2	-0.4	-0.8	1.8	-0.0	1.2	-0.6	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.4	0.3	-1.0	-0.6	-0.8	-1.2	-0.7	-0.7	0.6	-0.9	-0.5	-0.6	-0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.1	-0.6	-0.7	-1.0	-0.9	-0.5	-0.9	-0.5	0.1	-0.5	-0.8	-1.0	-0.9
Loneliness, isolation	0.4	0.6	2.1	-1.0	-0.4	-0.5	-0.7	0.0	-0.5	-0.7	-1.2	-0.1	-1.5	-0.8	-0.7
Average weekly beer plus cider intake	0.4	0.6	2.1	-0.5	-0.8	-0.7	-0.6	-0.7	-0.8	-0.9	0.3	-1.4	-0.9	-0.8	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.2	0.8	0.7	0.5	0.3	0.7	0.6	1.1	-0.7	0.9	0.1	0.9	0.9
Pack years of smoking	0.4	0.6	4.4	-0.8	-0.6	-0.4	-0.1	-0.9	-0.4	-0.5	2.1	0.5	0.2	-0.6	-0.5
Intelligence (Savage-Jansen 2018)	0.3	1.0	3.5	-0.1	-0.7	-1.2	-1.4	-0.8	-1.2	-0.9	0.3	-1.9	-0.3	-1.3	-1.0
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.9	0.1	-0.3	-0.8	-0.8	-0.3	-1.0	-0.7	-0.1	0.3	-0.8	-0.7	-1.0
Smoking Status	0.3	0.6	1.1	-0.0	-0.9	-0.7	-1.0	-1.0	-0.6	-0.8	1.1	-1.0	-0.7	-0.6	-0.9
Lung FVC	0.3	1.3	4.5	-2.1	-1.0	-1.0	-0.9	-0.1	-1.1	-1.4	-1.4	-1.5	-0.6	-0.9	-1.2
Number of treatments/medications taken	0.3	0.5	2.3	0.6	0.9	0.6	0.3	0.1	0.6	1.0	0.1	0.7	1.5	0.8	0.7
Hearing difficulty/problems: Yes	0.3	0.5	1.9	-0.2	0.3	0.5	0.7	1.4	0.6	0.5	-1.0	-0.1	1.1	0.5	0.8
Taking other prescription medications	0.3	0.5	2.5	1.0	0.3	0.3	0.1	1.0	0.3	0.4	-0.4	0.6	1.6	0.6	0.5
Qualifications: CSEs or equivalent	0.3	0.4	0.9	0.1	0.9	1.0	0.7	0.6	0.9	0.6	-0.7	0.6	0.3	0.6	0.5
Medication: Atenolol	0.3	0.3	1.1	0.2	0.8	0.5	0.0	0.4	0.6	1.0	-0.1	1.0	0.2	0.7	0.7
High blood pressure (mother)	0.3	0.4	3.6	-1.9	0.3	-0.1	-0.5	-0.5	-0.1	0.3	-0.7	0.4	-0.3	-0.3	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.2	-0.6	0.9	0.7	0.1	0.7	0.7	0.8	-0.9	0.1	-1.1	0.5	0.5
Medication: Cholesterol lowering	0.3	0.4	2.6	-1.6	-0.0	-0.7	-0.7	-0.5	-0.6	-0.4	0.3	-0.3	-0.5	-0.7	-0.4
Depression (self-reported)	0.3	0.4	1.0	1.0	0.5	0.4	0.8	0.2	0.4	0.8	1.0	0.5	0.6	0.6	0.6
Prospective memory result	0.3	0.4	2.4	-0.5	0.1	0.3	0.3	0.8	0.3	0.2	-0.9	1.5	-0.7	-0.0	-0.1
Lung cancer (father)	0.3	0.4	0.9	-0.7	-0.9	-0.8	-0.7	-0.4	-0.7	-0.6	0.3	0.9	-0.4	-0.6	-0.6
Pulse wave reflection index	0.3	0.4	1.8	-0.3	-0.2	-0.6	-0.7	-0.3	-0.6	-0.3	0.7	-1.3	0.6	-0.6	-0.6
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.3	1.5	0.2	0.9	0.8	0.4	0.8	0.4	-0.6	0.4	0.0	0.6	0.4
Body fat percentage	0.3	1.3	3.1	0.4	1.3	1.0	1.0	0.6	1.1	1.8	-1.0	1.5	1.0	1.3	1.5
Migraine (self-reported)	0.3	0.4	2.4	-0.4	0.5	0.2	0.3	0.5	0.2	0.5	-1.5	0.6	1.1	0.5	0.6
Had major operations	0.3	0.3	1.9	-0.4	0.2	-0.3	-0.6	-0.6	-0.1	0.2	0.4	1.4	-1.1	-0.2	0.3
Illnesses of siblings: Diabetes	0.3	0.3	0.9	-0.0	-0.7	-0.6	-0.3	-0.1	-0.7	-0.9	-0.1	-0.3	-1.0	-0.7	-0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	3.5	0.4	0.4	0.6	0.2	1.3	0.5	0.2	-1.9	-0.4	-0.7	0.1	0.0
Long-standing illness, disability or infirmity	0.3	0.4	2.1	0.7	0.3	0.3	0.4	1.4	0.3	0.5	-1.0	0.5	-0.1	0.4	0.4
Mineral and other dietary supplements	0.3	0.4	3.0	1.7	-0.0	0.1	0.2	0.9	0.1	0.1	0.3	0.6	0.6	0.5	0.2
Asthma (self-reported)	0.3	0.6	3.3	-0.1	0.3	0.4	0.8	1.3	0.4	0.2	-1.8	-0.7	-0.9	0.4	0.4
Medication: Aspirin	0.3	0.4	3.2	-1.0	-0.1	-0.3	-0.5	-0.1	-0.1	0.1	0.8	-0.1	1.8	0.1	0.1
Miserableness	0.3	0.5	2.8	-0.1	-0.5	-0.6	-0.2	-0.5	-0.6	-0.3	1.3	-0.1	-1.7	-0.7	-0.4
Medication: Paracetamol	0.3	0.4	3.2	0.5	0.6	0.3	0.4	-0.6	0.3	0.4	0.4	1.8	0.3	0.4	0.1
Unable to work because of sickness or disability	0.3	0.3	0.8	0.6	0.1	0.8	0.9	0.7	0.8	0.6	0.3	-0.3	0.1	0.7	0.7
Pain experienced in last month	0.3	0.5	1.2	-0.3	-0.8	-0.9	-0.8	-0.3	-0.9	-0.8	0.7	-0.5	-1.1	-0.7	-0.7
Basal cell carcinoma (self-reported)	0.3	0.3	3.7	-0.2	-0.2	-0.4	-0.1	0.2	-0.4	-0.3	-1.9	0.2	0.1	-0.1	-0.1
Heart disease (siblings)	0.3	0.3	1.6	-1.3	-0.4	-0.4	-0.3	-1.1	-0.2	-0.2	0.8	-0.0	0.2	0.0	0.4
Neuroticism (Nagel 2018)	0.2	0.4	1.0	-0.4	-0.8	-0.5	-0.8	-0.6	-0.5	-0.7	0.8	-0.4	-1.0	-0.6	-0.5
Reaction Time	0.2	0.4	1.0	-0.8	-0.6	-0.3	-0.5	-0.8	-0.4	-0.8	1.0	-0.5	0.2	-0.7	-0.7
HbA1C	0.2	0.3	1.8	-0.0	-0.7	-0.4	0.5	-1.4	-0.2	-0.4	0.3	0.1	0.1	-0.7	-0.3
HDL Cholesterol	0.2	0.3	1.0	0.1	-0.7	-0.7	0.5	-0.6	-0.6	-0.6	1.0	-0.3	0.3	-0.5	-0.5
Neuroticism (2016)	0.2	0.3	2.3	1.5	-0.1	0.2	0.1	0.3	0.2	0.0	1.0	0.2	-0.3	-0.0	0.1
Triglycerides	0.2	0.4	0.7	-0.3	-0.6	-0.3	-0.8	0.2	-0.4	-0.8	-0.8	-0.8	-0.8	-0.5	-0.6
Blood Red Count	0.2	1.9	5.5	0.1	1.6	1.4	1.3	0.6	1.6	1.0	-2.3	0.7	1.6	1.7	1.8
Heel T-Score	0.2	1.7	4.5	0.4	1.7	1.0	1.1	2.1	1.1	1.0	-1.6	1.3	1.2	1.6	1.3
Lung FEV1/FVC ratio	0.2	1.0	2.3	1.5	1.1	0.6	0.7	1.4	0.7	1.2	0.4	1.1	0.2	1.4	1.2
Average weekly spirits intake	0.2	0.2	1.0	0.1	-0.3	-0.3	-0.2	-0.8	-0.3	-0.3	-0.1	0.4	-1.0	-0.4	-0.4
Medication for hormone replacement therapy	0.2	0.3	1.4	1.2	0.0	-0.1	-0.0	-0.5	-0.1	0.4	1.0	0.4	-0.5	0.2	0.1
Vitamin and mineral supplements	0.2	0.3	2.6	0.0	-0.0	-0.2	-0.1	0.3	-0.1	-0.0	0.9	-0.5	1.6	0.5	0.3
Hand grip strength (right)	0.2	0.7	3.0	-0.9	1.1	0.5	-0.3	1.7	0.5	0.4	-1.3	-0.8	-0.3	0.6	0.5
Multivitamins +/- minerals	0.2	0.3	2.0	0.3	0.1	-0.1	-0.4	-0.3	-0.2	-0.1	-0.9	-0.4	-1.4	-0.5	-0.5
Medication: Levothyroxine sodium	0.2	0.4	2.3	1.5	0.0	0.7	0.6	0.3	0.7	0.4	0.0	0.3	0.7	0.5	0.6
Waist circumference	0.2	0.6	1.7	-0.8	-0.7	-0.6	-1.3	0.0	-0.6	-0.7	-0.5	-1.1	-1.0	-0.6	-0.5
Hair/balding pattern: Pattern 2	0.2	0.3	0.8	-0.0	0.4	0.5	0.9	0.8	0.5	0.4	-0.3	0.4	0.4	0.7	0.5
Had other major operations	0.2	0.2	1.0	1.0	0.3	0.2	-0.3	0.3	0.2	-0.1	-1.0	0.2	-0.7	0.4	0.3
Forced vital capacity (FVC)	0.2	0.7	4.5	-1.2	0.4	0.1	-0.4	0.8	-0.0	-0.4	-2.1	-1.1	-0.1	0.0	-0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.1	1.0	0.6	0.6	0.5	0.2	0.7	0.5	0.5	1.0	0.8	0.9	0.9
Allergy	0.2	0.4	2.8	-0.4	0.1	0.3	0.1	0.5	0.3	0.5	-0.3	0.9	1.7	0.5	0.6
Diabetes (self-reported)	0.2	0.3	3.0	-0.5	0.0	-0.1	-0.3	0.2	-0.2	-0.3	0.0	-1.7	-0.5	-0.2	-0.3
Medication: Ramipril	0.2	0.3	1.3	0.7	0.2	-0.5	-0.5	0.1	-0.5	-0.1	0.7	-1.1	-0.6	-0.4	-0.4
Number of live births	0.2	0.3	1.7	-1.3	-0.1	0.3	0.3	0.7	0.3	0.1	-0.5	0.6	0.3	0.2	0.2
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	5.5	-0.2	1.1	0.6	0.2	1.2	0.5	0.4	-2.4	-0.5	0.0	0.8	0.4
Pulse rate	0.2	0.3	1.8	-0.6	-0.3	-0.0	-0.4	1.3	-0.1	-0.6	0.1	-0.6	1.1	0.0	-0.2
Arm fat mass (right)	0.2	0.8	1.9	-1.3	-0.9	-1.0	-1.4	-0.9	-1.0	-0.5	0.3	-0.9	-0.8	-0.9	-0.7
Length of working week for main job	0.2	0.2	1.7	-1.3	0.0	-0.1	0.2	0.1	0.0	0.4	0.3	-0.1	0.7	-0.3	-0.0
Exposure to tobacco smoke at home	0.2	0.2	0.7	0.1	-0.1	0.1	-0.9	0.7	0.0	-0.5	-0.8	-0.2	-0.1	-0.0	-0.3
Hair/balding pattern: Pattern 4	0.2	0.5	1.2	-0.3	0.5	1.0	0.5	-0.1	1.1	0.8	-0.9	0.1	-0.3	0.7	1.1
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.7	-0.5	-0.3	-0.4	-0.7	0.8	-0.5	-0.6	-0.8	-0.8	-0.5	-0.6	-0.5
Medication: Paracetamol	0.2	0.4	1.2	-0.3	-0.3	-0.5	-0.2	-0.9	-0.5	-0.2	1.1	1.1	0.1	-0.4	-0.6
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.8	-0.4	-0.5	-0.5	-0.4	-0.4	-0.5	-0.7	0.7	-0.9	-0.5	-0.5	-0.6
Forced vital capacity (FVC), Best measure	0.2	0.8	4.4	-0.4	0.8	0.7	0.3	1.4	0.6	-0.0	-2.1	-1.0	0.4	0.6	0.2
Exposure to tobacco smoke outside home	0.2	0.3	1.1	0.2	-0.5	-0.2	-1.0	-0.5	-0.1	-0.9	-0.4	-0.1	-0.6	-0.4	-0.6
Health satisfaction	0.2	0.3	0.6	0.8	0.7	0.6	0.4	-0.4	0.5	0.7	0.5	-0.1	0.5	0.7	0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.9	0.0	-0.6	-0.1	-0.2	-0.0	-0.0	-0.1	-0.4	-0.6	-1.4	-0.0	0.1
Pulse rate, automated reading	0.2	0.6	1.6	-0.7	-0.9	-0.6	-0.5	1.1	-0.6	-1.0	1.0	-1.3	1.1	-0.2	-0.4
Alcohol intake frequency.	0.2	0.4	3.9	-2.0	-0.0	-0.0	-0.3	0.2	-0.0	-0.0	-0.5	-0.4	0.2	-0.4	-0.2
Suffer from ‘nerves’	0.2	0.4	1.0	-0.6	-0.6	-0.7	-0.8	-0.5	-0.7	-0.7	1.0	-0.5	-0.2	-0.7	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.3	1.1	0.2	0.2	0.2	1.1	0.2	0.3	0.3	0.7	-0.5	0.2	0.2
Medication: Aspirin	0.2	0.3	2.7	-0.8	-0.0	-0.2	-0.5	-0.1	-0.1	0.2	0.7	0.1	1.6	0.1	0.1
Supplements: Vitamin C	0.2	0.3	1.0	0.7	-0.1	0.4	0.5	-0.3	0.2	-0.4	0.5	1.0	-0.8	-0.4	-0.4
Diabetes diagnosed by doctor	0.2	0.4	2.2	0.4	0.7	0.6	0.4	0.5	0.6	0.4	-0.1	-1.5	-0.0	0.5	0.3
Eye problems/disorders: Cataract	0.2	0.2	1.4	0.2	0.0	-0.5	-0.2	1.2	-0.3	0.1	-0.5	0.3	-0.2	0.3	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	1.2	-0.6	0.2	0.1	-0.2	-0.3	0.0	0.2	-0.8	0.3	-1.1	-0.0	0.1
Osteoporosis (self-reported)	0.2	0.2	1.1	-0.4	-0.6	-0.1	0.0	-0.3	-0.0	-0.1	1.0	-1.0	0.7	-0.0	0.1
Osteoarthritis (self-reported)	0.2	0.2	0.7	-0.4	0.2	0.4	0.8	-0.5	0.4	0.5	0.3	-0.1	0.7	0.6	0.4
Ever taken oral contraceptive pill	0.2	0.3	1.1	-0.3	0.4	0.5	0.2	0.6	0.5	0.5	-1.1	-0.1	-1.0	0.0	0.5
Mother’s age at death	0.2	0.3	1.4	0.2	-0.1	-0.4	-0.4	-0.0	-0.4	-0.4	-1.2	-0.1	-1.2	0.0	-0.2
Financial situation satisfaction	0.2	0.2	0.5	0.5	0.5	0.5	0.6	-0.5	0.5	0.6	0.2	0.7	-0.3	0.2	0.5
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.3	-0.3	-0.0	-0.1	-0.0	-1.1	-0.0	-0.0	0.7	-0.5	0.3	-0.5	-0.1
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.4	-0.6	0.6	0.6	0.6	-0.2	0.6	0.6	-0.4	0.2	-0.2	0.4	0.5
Medication: Lisinopril	0.2	0.2	0.6	-0.4	-0.6	-0.3	-0.7	-0.8	-0.4	-0.4	0.7	0.3	-0.2	-0.4	-0.3
Medication: Atorvastatin	0.2	0.3	1.6	-0.0	0.5	-0.1	0.2	-0.2	0.1	0.7	1.3	-0.4	-0.8	0.2	0.5
Number of operations (self-reported)	0.2	0.3	1.9	0.5	0.2	-0.3	-0.6	-0.7	-0.2	-0.1	-0.1	1.0	-1.4	0.0	0.1
Alcohol drinker status: Previous	0.2	0.2	0.8	0.9	0.1	0.2	0.7	-0.1	0.2	0.3	-0.8	-0.6	-0.5	0.3	0.4
Schizophrenia vs Biploar Disorder	0.1	0.1	0.6	0.8	0.1	0.4	0.4	0.0	0.3	0.1	0.6	0.0	0.2	0.1	-0.2
Crohns Disease (2017)	0.1	0.2	0.8	-0.2	-0.2	-0.2	-0.9	0.6	-0.2	-0.7	-0.1	-0.7	-0.4	-0.1	-0.2
Prostate Cancer	0.1	0.1	0.8	0.9	-0.1	-0.2	0.1	0.3	-0.3	-0.1	-0.8	0.0	-0.2	-0.2	-0.1
Schizophrenia (2014)	0.1	0.3	0.7	0.8	-0.6	-0.5	-0.6	-0.2	-0.4	-0.8	0.2	0.0	-0.9	-0.7	-0.4
Blood White Count	0.1	0.5	2.7	-0.9	0.2	0.4	-0.0	0.7	0.4	0.1	-0.9	0.3	1.6	0.8	0.7
Height	0.1	2.7	5.1	-2.1	-1.2	-1.4	-2.2	-0.3	-1.5	-1.9	-2.0	-2.0	-2.0	-1.4	-1.4
Waist Hip Ratio (WHR)	0.1	0.7	1.4	1.2	0.6	1.2	0.7	1.0	1.1	0.4	-0.8	0.3	-0.8	0.8	0.8
Sensitivity / hurt feelings	0.1	0.1	0.9	-0.9	0.2	0.1	-0.6	-0.4	0.1	-0.0	0.3	0.0	-0.7	-0.1	0.0
Current tobacco smoking	0.1	0.1	0.4	-0.3	-0.5	-0.3	-0.6	-0.1	-0.2	-0.2	0.2	-0.5	-0.5	-0.2	-0.2
Maternal smoking around birth	0.1	0.2	0.7	0.2	0.3	0.2	0.2	0.2	0.3	0.7	0.7	0.8	0.3	0.4	0.5
Nervous feelings	0.1	0.2	0.5	0.1	0.3	0.5	0.6	-0.2	0.5	0.2	-0.3	0.7	0.6	0.5	0.5
Hearing difficulty/problems with background noise	0.1	0.2	1.6	0.4	-0.0	-0.1	-0.3	1.2	-0.1	0.1	-0.4	-0.6	0.4	0.2	0.1
Had menopause	0.1	0.1	0.6	-0.2	-0.2	0.3	0.7	-0.8	0.3	-0.0	0.1	0.1	0.6	-0.0	0.1
Mouth/teeth dental problems	0.1	0.1	0.3	-0.1	0.3	0.4	0.5	0.3	0.3	0.3	-0.5	-0.0	0.5	0.5	0.3
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	1.1	0.4	-0.1	-0.1	-0.2	-0.3	-0.1	0.1	1.1	-0.2	0.1	-0.0	-0.1
Hip circumference	0.1	0.3	1.2	-0.8	-0.4	-0.7	-1.1	-0.6	-0.6	-0.3	-0.2	-0.9	-0.4	-0.5	-0.4
Father’s age at death	0.1	0.1	0.5	-0.3	-0.1	-0.1	-0.2	0.4	-0.2	-0.4	-0.7	-0.2	0.2	-0.4	-0.4
Worrier / anxious feelings	0.1	0.1	0.4	-0.2	-0.2	0.4	-0.0	-0.1	0.4	-0.0	-0.3	0.6	-0.6	0.4	0.5
Falls in the last year	0.1	0.1	0.6	0.8	0.4	-0.0	0.1	0.2	0.1	0.5	0.5	0.6	0.0	0.4	0.2
Illnesses of mother	0.1	0.2	0.7	0.9	-0.4	-0.3	-0.2	0.6	-0.3	-0.5	-0.2	-0.5	-0.4	-0.0	-0.2
Standing height	0.1	0.6	3.3	-1.2	0.3	-0.1	-1.0	0.2	-0.2	-0.4	-1.8	-0.2	-1.1	-0.3	-0.4
Tense / ‘highly strung’	0.1	0.1	0.7	-0.3	-0.1	0.4	0.1	-0.8	0.4	-0.2	-0.1	-0.4	0.6	0.1	0.2
Headache pain in last month	0.1	0.2	0.8	0.1	0.4	0.4	-0.2	0.5	0.2	0.4	-0.9	0.5	0.6	0.4	-0.1
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.4	0.6	0.2	0.0	-0.4	-0.2	-0.0	-0.2	0.7	0.3	-0.3	-0.2	-0.2
Worry too long after embarrassment	0.1	0.2	0.7	0.5	0.3	0.5	0.4	0.8	0.4	0.2	-0.8	-0.2	-0.3	0.4	0.3
Number of children fathered	0.1	0.1	0.4	-0.5	0.2	-0.3	-0.4	0.0	-0.3	-0.1	0.6	0.2	-0.5	0.2	-0.1
Emphysema/chronic bronchitis	0.1	0.1	0.5	0.5	-0.2	0.0	0.3	-0.4	0.1	0.1	-0.5	0.7	-0.3	-0.1	0.2
Medication: Omeprazole	0.1	0.1	0.4	0.2	-0.2	-0.4	-0.4	-0.6	-0.2	0.1	0.1	0.1	-0.3	0.0	0.1
Number of full sisters	0.1	0.1	0.8	-0.9	-0.3	-0.2	-0.3	-0.6	-0.3	-0.1	0.3	0.5	-0.0	-0.2	-0.3
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.5	-0.1	-0.2	-0.4	-0.7	0.2	-0.4	-0.5	0.1	0.6	0.2	-0.3	-0.4
Mood swings	0.1	0.1	0.3	-0.2	0.3	0.4	0.1	0.5	0.4	0.5	0.1	0.3	-0.1	0.3	0.4
Back pain experienced in last month	0.1	0.2	1.6	-0.3	-0.3	0.1	-0.3	-0.6	0.1	-0.4	-0.0	-1.3	0.1	-0.3	-0.3
Breast cancer (self-reported)	0.1	0.1	0.6	-0.6	-0.3	-0.1	-0.3	0.1	-0.2	-0.0	-0.5	0.1	0.7	-0.0	-0.2
Smoking status: Current	0.1	0.1	0.7	-0.1	-0.6	-0.2	-0.6	-0.0	-0.1	-0.2	0.5	-0.3	-0.8	-0.2	-0.1
Arm fat mass (left)	0.1	0.6	1.5	-1.2	-0.7	-0.8	-1.2	-0.6	-0.8	-0.3	-0.1	-0.8	-0.6	-0.7	-0.5
Number of self-reported non-cancer illnesses	0.1	0.2	2.7	-1.6	-0.3	-0.2	-0.2	-0.0	-0.0	0.2	-0.0	0.0	0.1	0.0	0.4
Irritability	0.1	0.2	0.5	0.1	0.3	0.7	0.5	0.3	0.7	0.5	0.2	0.4	0.0	0.5	0.7
Risk taking	0.1	0.1	0.3	0.2	0.1	0.2	-0.4	0.6	0.3	0.0	0.1	-0.5	-0.5	0.1	0.0
Age started oral contraceptive pill	0.1	0.1	0.5	-0.2	-0.1	0.5	0.7	-0.0	0.5	-0.1	0.1	0.4	0.2	0.2	0.4
Worry (Nagel 2018)	0.0	0.1	0.6	-0.3	-0.3	0.0	-0.1	-0.8	0.1	-0.2	-0.1	-0.2	-0.0	0.1	0.2
Hair Pigment	0.0	0.4	2.5	-1.6	0.1	0.0	0.3	-0.8	0.1	0.3	-0.4	-0.8	-1.2	0.1	0.2
Tanning	0.0	0.3	1.5	-0.2	-0.5	-0.8	0.1	0.5	-0.6	-0.1	1.2	0.4	-0.0	-0.1	0.2
Trunk fat mass	0.0	0.2	0.8	-0.7	0.3	0.0	-0.2	0.0	0.1	0.7	-0.9	0.6	-0.1	0.2	0.5
Arm fat percentage (right)	0.0	0.1	0.2	-0.2	-0.2	-0.3	-0.4	-0.3	-0.3	0.3	0.3	-0.1	0.2	-0.1	0.1
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.5	-0.7	-0.5	-0.2	-0.2	-0.4	-0.2	-0.1	-0.1	-0.1	0.1	-0.2	-0.0
Whole body fat mass	0.0	0.2	0.7	-0.8	0.1	-0.1	-0.5	-0.3	-0.1	0.5	-0.8	0.2	-0.3	0.0	0.2
Leg fat mass (right)	0.0	0.2	1.3	-1.1	0.2	0.1	-0.3	-0.1	0.2	0.5	-0.6	0.4	0.0	0.1	0.4
Comparative height size at age 10	0.0	0.1	0.5	-0.2	0.3	0.2	-0.6	-0.1	0.0	-0.2	-0.2	0.3	0.7	0.1	-0.1
Arm fat percentage (left)	0.0	0.1	0.1	-0.2	-0.2	-0.3	-0.3	-0.4	-0.2	0.3	0.2	-0.1	0.1	-0.1	0.1
Leg fat mass (left)	0.0	0.2	1.1	-1.1	0.2	-0.0	-0.4	-0.1	0.1	0.5	-0.6	0.5	-0.0	0.1	0.3

Hub : Genes

RARRES2

Models

Trait associations