TWAS hub - RARS2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0840	0.0280	6.5e-06	0.022	0.038	0.033	0.037	0.029	9.1e-04	1.9e-05	6.8e-05	2.5e-05	1.8e-04
2	GTEx	Cells Transformed fibroblasts	0.1020	0.0440	7.7e-03	0.067	NA	0.065	NA	0.069	9.4e-06	NA	1.3e-05	NA	6.8e-06
3	GTEx	Esophagus Mucosa	0.1500	0.0540	2.9e-03	0.046	NA	0.057	NA	0.064	4.9e-04	NA	1.1e-04	NA	4.4e-05
4	GTEx	Muscle Skeletal	0.1433	0.0451	1.1e-05	0.070	NA	0.036	NA	0.054	2.2e-07	NA	1.8e-04	NA	5.2e-06
5	GTEx	Nerve Tibial	0.1048	0.0405	7.5e-04	0.029	NA	0.036	NA	0.035	3.7e-03	NA	1.4e-03	NA	1.5e-03
6	GTEx	Skin Sun Exposed Lower leg	0.0780	0.0370	3.9e-03	0.011	NA	0.027	NA	0.012	3.6e-02	NA	2.4e-03	NA	3.3e-02
7	YFS	Blood	0.0765	0.0169	0.0e+00	0.049	0.065	0.068	0.063	0.070	1.0e-15	2.6e-20	2.1e-21	7.5e-20	5.8e-22
8	TCGA	Breast Invasive Carcinoma	0.0255	0.0157	7.9e-03	0.006	0.009	0.010	NA	0.008	1.9e-02	4.2e-03	2.5e-03	NA	7.2e-03
9	TCGA	Lung Adenocarcinoma	0.0524	0.0302	9.5e-03	0.021	0.002	0.004	NA	0.011	1.5e-03	1.9e-01	9.4e-02	NA	1.7e-02
10	TCGA	Lung Squamous Cell Carcinoma	0.0840	0.0388	3.7e-04	0.019	0.032	0.037	NA	0.029	2.4e-03	1.2e-04	4.4e-05	NA	2.7e-04
11	TCGA	Thyroid Carcinoma	0.0740	0.0380	5.3e-03	0.037	0.029	0.036	NA	0.037	1.4e-04	7.7e-04	1.8e-04	NA	1.6e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Qualifications: None of the above	4.8	10.3	30.8	-1.7	0.1	-0.1	-5.6	-4.1	-1.8	-1.5	-1.4	-5.2	-2.7	-4.6
Birth weight	4.7	10.1	19.1	3.4	-0.3	0.9	3.8	4.4	3.7	2.3	3.1	4.1	3.1	3.3
Qualifications: College or University degree	4.7	14.9	34.0	3.5	-1.8	-0.4	5.4	5.8	2.9	3.6	2.1	5.5	3.2	4.3
Hypothyroidism/myxoedema (self-reported)	3.8	7.4	15.2	-3.5	0.2	-0.8	-3.3	-3.9	-3.3	-2.5	-2.0	-3.2	-2.1	-2.5
Medication: Seretide 50 evohaler	3.8	4.4	9.0	-3.0	-0.3	-1.1	-1.8	-2.9	-2.6	-2.2	-2.1	-2.0	-1.6	-1.9
Ever taken oral contraceptive pill	3.8	4.2	11.9	3.4	0.4	0.8	1.8	2.4	2.6	-0.4	2.4	1.8	2.6	1.6
Commuting to job workplace: Public transport	3.4	4.0	6.5	2.4	1.3	1.5	2.3	2.5	1.4	0.5	2.0	2.1	2.5	2.4
Commuting to job workplace: Cycle	3.3	4.0	7.8	1.7	0.6	0.5	2.7	2.3	2.2	-0.2	1.4	2.8	2.3	2.8
Age at first live birth	3.2	5.7	9.9	2.2	1.1	1.7	2.8	2.9	1.9	1.0	2.8	2.9	2.5	3.1
Illness, injury, bereavement, stress in last 2 years	3.2	4.0	9.1	2.0	-0.3	-0.1	3.0	2.7	1.6	-0.3	1.1	3.0	2.1	2.5
Smoking Status	3.0	7.3	13.9	-2.6	-0.1	-0.7	-3.7	-3.2	-1.4	-2.8	-2.4	-3.7	-2.4	-3.7
Medication: Ventolin 100micrograms inhaler	2.8	3.5	10.6	-0.1	1.3	0.1	-2.5	-2.3	-0.7	-3.2	-1.4	-2.9	-0.7	-1.9
Angina (self-reported)	2.8	3.7	7.9	0.1	2.7	2.8	-0.1	-0.2	2.8	-1.9	2.4	-0.0	2.5	1.1
Overall health rating	2.8	6.1	11.1	-2.6	-0.9	-1.1	-3.3	-2.9	-2.2	-0.6	-2.3	-3.3	-2.6	-3.2
Hypothyroidism (self reported)	2.7	6.2	13.5	-3.7	0.7	-0.7	-2.7	-3.4	-3.3	-2.1	-2.1	-2.7	-2.0	-1.9
Supplements: Glucosamine	2.7	3.5	5.6	1.5	1.1	1.7	1.6	2.4	2.3	2.0	2.2	1.6	1.9	1.9
Taking other prescription medications	2.6	4.1	9.8	-2.3	1.0	0.5	-3.1	-2.4	-1.5	-0.3	-1.0	-3.1	-1.8	-2.6
Number of self-reported non-cancer illnesses	2.6	4.5	11.0	-3.3	1.6	0.7	-3.0	-2.8	-0.8	-2.1	-0.9	-2.9	-1.0	-1.9
Medication: Levothyroxine sodium	2.5	4.2	8.4	-2.6	-0.3	-1.1	-2.2	-2.6	-2.9	-2.3	-1.6	-2.2	-1.5	-1.8
Eye problems/disorders: Glaucoma	2.5	2.9	8.9	-1.2	-1.7	-1.7	-1.3	-0.9	-3.0	1.0	-1.8	-1.2	-2.2	-1.8
Angina	2.4	3.2	7.4	0.0	2.4	2.5	-0.1	-0.3	2.7	-1.9	2.2	-0.0	2.4	1.1
Tinnitus: Yes, but not now, but have in the past	2.4	2.5	6.3	-0.7	-0.1	-0.7	-2.1	-2.1	-1.4	-2.5	-1.0	-2.1	-1.0	-1.7
Qualifications: A levels/AS levels or equivalent	2.4	5.3	13.0	2.3	0.5	1.4	2.9	3.6	1.8	1.4	1.8	2.6	2.7	2.6
Mouth/teeth dental problems: Dentures	2.4	4.0	10.3	-1.6	1.1	0.0	-3.2	-2.6	-0.5	-2.4	-1.2	-2.9	-1.5	-2.3
Mineral and other dietary supplements	2.4	3.2	6.1	-2.4	-0.2	-0.8	-1.8	-2.3	-2.5	-0.1	-1.7	-1.9	-2.2	-1.9
Bipolar Disorder (2011)	2.3	2.2	5.2	-1.1	2.2	1.4	-2.2	-1.3	0.2	-1.2	-0.5	-2.3	-0.2	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.3	3.1	7.7	-0.8	0.0	-0.4	-2.8	-2.0	-1.7	-1.1	-1.3	-2.6	-1.5	-2.6
Age at last live birth	2.3	3.3	5.1	2.1	0.9	1.4	1.9	2.0	2.0	0.5	2.0	2.2	2.0	2.3
Medication: Aspirin	2.3	3.0	6.9	2.1	0.9	2.0	0.2	2.3	2.6	0.4	2.2	0.2	2.5	0.6
Age at First Birth	2.2	3.2	8.1	0.3	0.9	1.0	2.7	2.1	1.1	1.6	1.1	2.8	1.2	2.6
Medication: Cholesterol lowering	2.2	3.4	6.2	0.9	2.5	2.5	1.2	1.4	2.2	0.3	2.5	1.1	2.3	1.9
Forced expiratory volume in 1-second (FEV1), Best measure	2.2	6.9	11.6	2.9	0.6	1.3	2.9	3.1	3.4	0.7	2.9	2.8	3.1	3.0
Wheeze or whistling in the chest in last year	2.2	4.0	8.0	-1.7	-1.9	-2.8	-0.6	-2.6	-2.3	-1.7	-2.7	-0.6	-1.9	-1.6
Qualifications: nursing, teaching	2.2	3.4	9.9	-0.3	-0.2	0.0	3.1	2.5	0.5	2.1	0.9	2.9	0.9	2.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.2	2.6	7.0	-0.3	2.4	2.7	-0.1	-0.1	2.2	-0.1	2.4	0.2	1.8	1.0
Asthma (self-reported)	2.2	4.3	10.6	-1.8	0.8	-0.3	-2.2	-2.7	-2.1	-3.3	-2.4	-2.3	-1.4	-1.8
Health satisfaction	2.1	2.7	10.3	-2.3	-0.3	-1.1	-1.3	-3.2	-2.0	-0.4	-1.4	-1.3	-1.4	-1.3
Smoking status: Current	2.1	3.3	7.7	-1.7	-0.7	-0.9	-2.2	-1.9	-0.9	-1.7	-2.0	-2.3	-1.9	-2.8
Diabetes (mother)	2.0	2.6	7.5	0.4	-0.1	0.2	-2.7	-1.3	-1.3	-0.8	-1.2	-2.7	-1.5	-2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.0	2.3	8.0	-0.6	0.1	0.2	-2.8	-1.2	-0.5	-0.9	-0.9	-2.8	-1.3	-2.1
Supplements: Fish oil (including cod liver oil)	2.0	2.7	5.3	2.3	-1.5	-1.0	2.0	2.1	1.7	-0.5	0.4	2.1	1.6	1.4
Depression (Nagel 2018)	1.9	2.8	10.1	-0.1	-0.2	-0.1	-3.2	-1.4	-1.0	-0.5	-0.6	-2.9	-1.0	-2.8
High blood pressure (mother)	1.9	2.6	4.7	1.4	1.8	1.7	1.3	1.1	2.1	-0.5	2.0	1.3	2.2	1.9
Noisy workplace	1.9	2.4	4.3	-1.4	-0.3	-1.1	-2.0	-2.1	-1.4	-0.8	-1.4	-1.8	-2.0	-1.6
Eye problems/disorders: Cataract	1.9	2.2	3.6	1.3	1.1	1.5	1.8	1.6	1.0	0.4	1.7	1.6	1.9	1.8
Relative age voice broke	1.8	2.8	9.3	-1.6	0.7	0.0	-1.7	-0.6	-3.0	0.7	-2.1	-2.0	-2.2	-1.4
Asthma	1.8	3.6	9.6	-1.7	1.1	0.0	-2.1	-2.5	-1.7	-3.1	-2.1	-2.2	-1.1	-1.6
Medication: Lansoprazole	1.8	2.1	4.4	-1.1	-1.3	-0.7	-1.9	-1.9	-1.4	0.3	-0.7	-1.9	-1.4	-2.1
Medication for cholesterol, blood pressure or diabetes	1.8	3.0	5.6	-1.0	-1.6	-1.7	-1.8	-1.5	-2.1	-0.6	-2.4	-1.7	-2.2	-2.0
Forced vital capacity (FVC), Best measure	1.8	6.7	14.5	2.3	1.1	1.6	2.7	2.9	3.8	0.8	2.9	2.8	3.0	3.0
Long-standing illness, disability or infirmity	1.8	2.8	5.1	-2.1	-0.5	-0.7	-2.1	-1.9	-1.4	-0.2	-1.7	-2.3	-1.7	-2.1
Illnesses of father: None of the above (group 1)	1.8	2.2	4.7	-0.3	-1.1	-0.4	-2.1	-1.2	-1.8	0.3	-1.2	-2.1	-1.7	-2.2
Supplements: Zinc	1.7	1.8	5.1	-0.5	2.3	2.1	-1.4	-0.9	0.3	-2.1	0.9	-1.3	0.6	-0.2
Current tobacco smoking	1.7	2.8	7.4	-1.5	-0.5	-0.6	-2.2	-1.6	-0.7	-1.6	-1.7	-2.3	-1.7	-2.7
Average weekly fortified wine intake	1.7	2.0	4.2	1.9	0.6	1.2	0.7	2.0	1.5	-0.7	1.8	1.2	1.9	1.0
Chronic bronchitis/emphysema (father)	1.7	1.9	3.8	-2.0	0.5	0.1	-1.7	-1.8	-1.1	-0.6	-1.0	-1.9	-1.7	-1.4
Qualifications: O levels/GCSEs or equivalent	1.7	2.7	6.9	1.7	-0.6	0.1	2.6	2.3	0.6	1.0	0.7	2.3	1.6	2.1
Glaucoma (self-reported)	1.7	2.0	5.4	-1.0	-2.1	-2.1	-0.2	-0.5	-2.3	0.7	-1.8	-0.1	-1.5	-1.0
Medication: Aspirin	1.7	2.2	4.5	1.9	0.8	1.9	-0.1	2.0	2.1	0.9	1.7	-0.1	2.0	0.3
Crohns Disease (2017)	1.6	3.5	9.3	-1.5	2.8	2.0	-2.3	-1.7	0.6	-3.0	0.1	-2.3	0.2	-0.8
Risk taking	1.6	2.4	7.0	1.3	0.8	1.4	0.8	1.2	2.6	-1.3	1.9	0.8	2.1	1.4
Ever used hormone-replacement therapy (HRT)	1.5	1.9	3.3	-1.0	-1.6	-1.8	-1.2	-1.2	-1.6	-0.0	-1.8	-0.9	-1.4	-1.6
Impedance of leg (right)	1.5	7.5	21.5	-4.6	3.5	1.9	-2.5	-4.1	-1.5	-2.9	-1.2	-2.6	-1.7	-0.8
Impedance of leg (left)	1.5	7.4	18.8	-4.3	3.1	1.4	-2.8	-4.0	-2.0	-2.2	-1.7	-2.9	-2.3	-1.2
Alcohol usually taken with meals	1.5	2.4	5.9	0.2	0.0	0.4	2.4	1.9	1.0	1.6	1.0	2.4	1.3	2.3
Medication: Simvastatin	1.5	2.2	5.0	0.5	1.1	1.7	1.2	1.2	1.7	1.9	2.2	1.0	1.8	1.4
Basal cell carcinoma (self-reported)	1.5	1.8	3.1	-0.4	-1.7	-1.5	-1.3	-1.3	-0.6	-1.4	-1.5	-1.3	-1.3	-1.8
Respiratory disease	1.4	3.1	9.1	-0.9	1.3	0.5	-2.2	-2.2	-0.8	-3.0	-1.8	-2.3	-1.1	-1.4
Frequency of depressed mood in last 2 weeks	1.4	2.0	5.5	-0.9	-0.2	-0.3	-2.3	-1.7	-1.1	-1.1	-0.8	-2.1	-0.9	-2.1
Qualifications: CSEs or equivalent	1.4	1.8	6.6	-2.6	0.5	-0.5	-1.1	-2.4	-0.7	-0.8	-1.0	-1.1	-1.6	-0.7
Past tobacco smoking	1.4	2.6	5.3	2.3	-0.7	0.2	2.2	2.3	0.8	1.9	1.0	1.9	1.2	1.7
Alcohol intake versus 10 years previously	1.4	2.1	3.7	-0.8	-0.2	-0.9	-1.5	-1.9	-1.9	-1.2	-1.7	-1.8	-1.5	-1.6
Forced expiratory volume in 1-second (FEV1)	1.4	4.6	9.3	1.7	0.4	0.6	2.8	2.3	3.0	0.4	1.9	2.8	2.4	2.7
Medication: Omeprazole	1.4	1.7	5.0	-0.3	-0.1	-0.1	-2.2	-1.0	-0.6	-0.9	-0.9	-2.2	-1.3	-2.0
Pain type(s) experienced in last month: Hip pain	1.4	1.7	4.7	-1.3	1.3	1.2	-2.1	-1.2	-0.6	-1.1	0.1	-2.2	-0.5	-1.3
Ever smoked	1.4	2.5	4.5	-1.9	0.2	-0.7	-1.9	-2.1	-0.9	-2.1	-1.5	-1.7	-1.4	-1.8
Ever depressed for a whole week	1.4	1.7	4.1	0.8	-0.7	-1.0	-1.9	-0.7	-0.9	-0.8	-1.7	-2.0	-1.2	-1.6
Pack years of smoking	1.4	2.0	4.0	0.2	-1.5	-1.8	-1.2	-0.9	-1.4	-1.0	-2.0	-1.5	-1.2	-2.0
Crohns Disease (2012)	1.3	2.0	8.9	-1.0	2.0	1.1	-1.4	-1.5	0.3	-3.0	-0.7	-1.5	0.4	-0.3
Pack years adult smoking proportion	1.3	2.0	4.2	0.3	-1.4	-1.7	-1.1	-1.0	-1.4	-1.0	-2.1	-1.5	-1.3	-1.9
Diverticular disease/diverticulitis (self-reported)	1.3	1.6	8.1	0.5	-0.4	0.1	1.5	1.8	-0.1	2.9	0.8	1.2	0.8	0.9
Forced vital capacity (FVC)	1.3	5.1	11.7	1.5	0.7	1.0	2.8	2.3	3.4	0.5	2.1	2.9	2.5	2.9
Number of full brothers	1.3	1.7	7.8	-1.7	-0.0	-0.6	-0.8	-2.8	-0.3	-1.8	-0.9	-1.1	-0.7	-0.7
Neck or shoulder pain in last month	1.3	1.9	5.4	-1.9	1.2	0.3	-1.1	-2.3	0.2	-2.3	-0.8	-1.3	-0.7	-0.9
Alcohol intake frequency.	1.3	3.0	6.5	-1.9	0.8	-0.0	-2.1	-2.3	-1.4	-0.1	-1.9	-2.6	-2.2	-1.6
Number of full sisters	1.3	1.5	6.3	-0.3	0.2	0.8	-2.1	-1.8	-0.3	-0.4	0.2	-2.5	-0.2	-1.4
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.6	3.9	-1.4	0.6	-0.6	-1.3	-1.7	-0.5	-2.0	-1.0	-1.6	-0.9	-1.2
Back pain experienced in last month	1.3	1.9	4.4	-1.5	-0.1	-0.3	-1.9	-2.1	-0.7	-1.1	-1.1	-2.0	-1.1	-1.6
Leg fat percentage (left)	1.3	4.7	11.5	-0.9	0.5	0.1	-3.3	-2.3	-2.8	-0.7	-1.4	-3.4	-2.1	-2.9
Pain experienced in last month	1.3	2.2	5.3	2.2	-0.3	0.4	1.9	2.3	0.8	0.6	1.3	1.9	1.4	1.5
Had menopause	1.2	1.5	4.4	-0.2	-2.1	-1.7	-0.6	0.0	-1.7	1.1	-1.2	-0.2	-1.2	-1.1
Mouth/teeth dental problems	1.2	1.8	5.7	-0.4	-1.1	-0.8	2.4	1.3	-0.2	1.7	0.1	2.3	0.5	1.6
Blood clot in the leg (DVT)	1.2	1.6	4.5	-1.6	-0.0	-0.2	-1.5	-2.1	-1.3	-1.3	-0.7	-1.5	-0.6	-1.1
Leg fat percentage (right)	1.2	4.3	10.9	-1.0	0.8	0.5	-3.2	-2.4	-2.5	-1.2	-1.1	-3.3	-1.7	-2.6
Average weekly red wine intake	1.2	1.8	3.8	1.1	0.3	1.0	1.5	1.7	1.7	0.5	1.0	1.4	1.9	1.7
Handedness (chirality/laterality): Left-handed	1.2	1.4	3.8	-0.6	-1.9	-1.7	-0.4	-0.6	-1.4	-0.4	-1.6	-0.4	-1.4	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	3.9	1.2	0.9	1.3	-1.2	0.1	1.2	-2.0	0.7	-1.1	0.9	-0.5
Wears glasses or contact lenses	1.2	1.4	3.6	1.1	-1.9	-1.5	0.7	1.0	-1.4	1.6	-0.9	0.8	-0.8	0.0
Illnesses of father: High blood pressure	1.2	1.5	4.2	0.3	1.4	1.0	0.7	0.8	2.1	-0.2	1.3	0.7	1.9	1.3
Alcohol drinker status: Never	1.2	1.5	2.6	-0.4	-1.3	-1.3	-1.0	-1.0	-1.4	-0.1	-1.6	-1.2	-1.6	-1.4
Mean Putamen Volume	1.1	1.3	3.5	-0.1	-1.5	-1.7	1.1	0.2	-1.9	0.5	-1.4	0.7	-1.1	0.2
Lung FVC	1.1	5.8	14.8	3.3	0.4	1.2	2.0	2.9	3.8	0.1	2.5	2.0	3.2	2.0
Townsend deprivation index at recruitment	1.1	1.5	3.7	0.2	1.6	1.3	-1.6	-0.8	0.7	-1.9	0.0	-1.8	0.4	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.5	5.5	-1.7	-0.5	-1.0	-1.7	-1.1	-1.8	1.5	-1.8	-1.6	-2.3	-1.6
Financial difficulties in last 2 years	1.1	1.5	5.0	-0.3	0.7	0.7	-2.2	-1.3	-0.2	0.2	-0.2	-2.1	-0.9	-1.7
Fluid intelligence score	1.1	2.3	8.1	-0.7	-0.1	0.0	2.6	1.5	-0.4	0.7	0.5	2.9	0.7	2.5
Pulse wave reflection index	1.1	1.3	7.9	2.8	-0.1	0.3	0.8	1.2	1.1	-0.2	0.6	0.7	1.4	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	5.3	-1.2	1.0	0.9	1.1	-0.2	2.3	-0.3	1.3	1.1	1.1	1.5
Alcohol drinker status: Previous	1.1	1.3	3.4	-1.0	1.4	1.1	-1.8	-1.2	-0.3	-1.0	-0.1	-1.9	-0.2	-0.8
Intelligence (Savage-Jansen 2018)	1.0	2.9	8.6	0.1	0.3	0.9	2.7	1.9	-0.1	0.8	1.4	2.9	1.2	2.8
Irritable Bowel Disease (IBD)	1.0	2.4	5.7	-0.5	2.3	2.1	-2.1	-0.7	0.9	-2.4	0.7	-1.9	0.3	-0.7
Major Depression (MDD)	1.0	1.3	3.1	0.2	-0.8	-1.1	-1.5	-0.0	-0.7	0.0	-1.6	-1.4	-1.3	-1.8
Reaction Time	1.0	1.8	5.1	-1.1	0.1	-0.2	-2.3	-2.1	-1.0	-0.8	-0.5	-2.0	-1.1	-1.6
Fasting Glucose	1.0	1.2	3.0	1.1	1.1	1.7	-0.4	0.1	0.9	-1.4	1.7	-0.6	1.2	-0.1
Triglycerides	1.0	1.7	4.0	-1.7	0.6	0.7	-1.6	-2.0	-0.5	-1.8	-0.3	-1.7	-0.2	-1.3
Type 2 Diabetes (T2D) (2012)	1.0	1.2	3.3	-1.2	0.3	-0.1	-1.4	-1.6	0.1	-1.0	-0.6	-1.8	-1.0	-1.3
Number of treatments/medications taken	1.0	1.7	4.0	-1.9	0.6	0.1	-2.0	-1.3	-1.2	0.2	-0.2	-2.0	-1.1	-1.7
Maternal smoking around birth	1.0	1.5	3.2	-0.2	1.5	1.4	-1.8	-1.3	0.4	-1.7	0.6	-1.7	0.4	-0.8
Serious illness, injury or assault to yourself	1.0	1.2	4.0	-0.4	-0.2	0.1	-2.0	-0.2	-0.3	1.2	-0.2	-1.8	-1.0	-1.8
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	2.7	0.2	-0.6	-0.8	-1.6	-0.6	-0.2	-0.5	-1.6	-1.6	-1.4	-1.4
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	2.2	-1.5	1.4	1.5	-1.4	-1.4	-0.5	-0.4	0.2	-1.5	-0.1	-0.6
Prospective memory result	1.0	1.2	3.5	0.3	1.9	1.6	-0.3	0.0	1.4	-1.3	1.4	0.0	0.9	0.7
Commuting to job workplace: Car/motor vehicle	1.0	1.2	4.0	-2.0	-0.1	-0.4	-0.7	-1.5	-0.8	-1.2	-1.1	-1.0	-0.9	-0.9
Irritability	1.0	1.7	3.1	1.1	0.7	0.9	1.8	1.2	1.2	-0.1	1.5	1.7	1.7	1.5
Deep venous thrombosis (DVT) (self-reported)	1.0	1.2	3.7	-1.3	-0.1	-0.1	-1.4	-1.9	-1.2	-1.0	-0.6	-1.5	-0.4	-1.0
Heart disease (siblings)	1.0	1.3	5.1	0.1	2.3	2.0	-0.7	-0.3	1.4	-1.1	0.6	-0.8	0.7	0.4
Allergy	0.9	2.0	6.1	2.5	-0.9	0.4	0.8	1.9	1.5	1.5	1.7	1.0	1.4	0.8
Falls in the last year	0.9	1.3	4.2	0.7	0.8	1.6	-0.4	1.2	1.1	1.6	2.1	-0.1	0.7	0.1
Lung cancer (father)	0.9	1.0	1.9	-1.1	-0.8	-0.8	-0.8	-0.3	-1.2	1.3	-0.9	-0.8	-1.4	-1.3
Birth weight of first child	0.9	1.6	4.6	-0.6	-1.4	-1.1	2.1	1.5	0.3	1.1	-0.3	2.1	0.2	1.2
Gout (self-reported)	0.9	1.3	3.4	-0.9	-1.8	-1.8	-0.7	-1.0	-1.3	-0.4	-1.2	-0.5	-0.9	-1.0
Illnesses of father: Heart disease	0.9	1.2	2.2	0.2	1.3	1.3	1.1	0.9	0.6	0.9	1.4	1.1	1.1	1.5
Leg fat-free mass (right)	0.9	4.8	14.7	3.8	-2.7	-1.6	2.0	3.3	1.2	2.3	0.9	2.2	0.9	0.7
Leg predicted mass (right)	0.9	4.7	14.8	3.8	-2.7	-1.5	2.0	3.3	1.2	2.2	0.8	2.1	0.9	0.6
Impedance of whole body	0.9	4.4	12.4	-3.5	2.8	1.3	-1.8	-3.1	-1.5	-1.6	-1.2	-2.0	-1.6	-0.5
Worry (Nagel 2018)	0.8	1.6	9.5	-3.1	0.0	-0.6	-0.9	-1.8	-0.4	-0.5	-1.1	-0.8	-1.0	-0.6
Primary Biliary Cirrhosis	0.8	1.2	5.8	1.1	0.5	1.2	-0.2	0.6	2.4	-1.0	1.3	-0.2	1.1	0.2
Schizophrenia (2014)	0.8	1.7	5.3	-2.0	0.6	0.4	1.1	0.2	2.1	2.3	0.6	1.0	-0.2	1.2
Severe depression (siblings)	0.8	0.8	2.1	0.8	-0.1	-0.1	1.4	1.0	0.9	-0.5	0.2	1.4	1.2	1.0
Pain all over the body in last month	0.8	0.9	2.8	-0.6	1.2	0.5	-1.5	-1.1	-0.2	0.1	-0.3	-1.7	-0.3	-1.1
Exposure to tobacco smoke at home	0.8	0.9	4.9	-0.4	2.2	1.6	-0.9	-0.1	-0.2	-0.2	0.6	-0.9	0.3	-0.1
Medication: Amlodipine	0.8	1.1	2.0	-0.2	-0.9	-1.4	-0.8	-0.4	-1.4	-0.1	-1.4	-1.1	-1.3	-1.3
Chronic bronchitis/emphysema (mother)	0.8	0.9	1.9	0.6	-0.5	-0.1	-1.2	0.4	0.4	1.4	-0.5	-1.4	-1.3	-1.3
Mouth/teeth dental problems: Loose teeth	0.8	1.0	1.7	-0.0	-0.2	-0.6	-1.1	-1.3	-0.7	-1.0	-0.9	-1.3	-1.3	-1.2
Migraine (self-reported)	0.8	1.0	5.6	-0.4	-1.0	-1.4	0.2	0.0	-2.4	-0.1	-1.3	0.3	-0.9	-0.0
Ever had bowel cancer screening	0.8	0.9	1.9	0.1	-1.0	-0.6	1.2	1.3	1.2	0.6	0.6	1.4	1.1	0.9
Diabetes diagnosed by doctor	0.8	1.4	3.8	0.7	1.0	1.5	0.7	0.8	1.5	1.9	1.5	0.5	0.9	1.0
Medication: Gliclazide	0.8	0.9	1.7	0.4	1.3	1.1	0.8	0.8	1.3	-0.2	1.2	0.6	1.2	1.0
Average weekly champagne plus white wine intake	0.8	1.1	2.9	0.2	0.1	0.6	1.7	1.0	0.8	1.4	0.8	1.4	0.7	1.4
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	2.7	-0.8	-0.0	0.0	-1.6	-1.0	-0.2	-0.4	-0.3	-1.6	-1.0	-1.6
Alzheimer’s Disease (in father)	0.7	0.7	2.6	0.4	0.9	0.7	0.3	0.5	1.6	-1.1	0.5	0.6	0.8	0.8
HbA1C	0.7	0.8	1.9	0.8	0.6	1.3	0.6	0.4	1.4	-0.3	1.1	0.5	1.0	0.9
Lupus	0.7	1.0	3.4	1.1	1.3	1.9	-0.3	0.8	1.1	0.1	1.4	-0.3	0.7	0.2
Blood Eosinophil Count	0.7	5.1	15.8	-4.0	1.1	-0.2	-1.5	-3.4	-2.7	-1.4	-2.4	-1.9	-2.5	-1.0
Waist Hip Ratio (WHR)	0.7	3.3	8.1	-1.4	1.9	1.1	-2.5	-2.1	-0.4	-2.8	-0.7	-2.6	-0.7	-1.6
Allergy or Eczema	0.7	1.7	5.7	-2.0	0.7	-0.4	2.4	0.3	-0.9	1.0	-0.6	1.9	0.1	1.6
Chronotype (morning person)	0.7	1.7	13.4	3.7	-0.5	-0.6	1.1	1.3	-0.0	-0.6	-0.2	0.9	0.3	0.5
Average weekly spirits intake	0.7	0.8	3.5	-1.9	-0.1	-0.5	-0.4	-1.1	-1.0	0.7	-0.5	-0.4	-1.2	-0.7
Medication for hormone replacement therapy	0.7	0.7	2.2	-0.2	0.5	0.5	0.9	-0.6	-0.2	-1.5	0.8	1.1	1.1	1.1
Leg fat-free mass (left)	0.7	3.9	12.5	3.5	-2.4	-1.3	1.9	2.9	1.2	1.7	1.0	2.0	1.1	0.7
Multivitamins +/- minerals	0.7	0.9	1.8	1.0	0.2	0.4	0.7	1.1	1.3	-0.9	1.1	1.0	1.3	0.9
Leg predicted mass (left)	0.7	3.8	12.2	3.5	-2.5	-1.4	1.9	2.8	1.1	1.7	0.9	2.0	1.0	0.7
Diabetes (self-reported)	0.7	1.0	6.9	1.3	-0.5	0.2	0.5	0.9	0.8	2.6	0.8	0.4	0.0	0.3
Illnesses of siblings	0.7	0.9	3.8	0.1	-0.7	-0.5	1.8	0.5	0.2	0.8	0.6	1.9	0.5	1.1
Body fat percentage	0.7	2.8	6.3	-0.2	0.4	0.1	-2.4	-1.5	-2.5	-0.1	-1.2	-2.5	-1.8	-2.2
Shortness of breath walking on level ground	0.7	0.8	1.9	-0.5	-1.4	-0.6	-1.2	-1.1	-0.2	0.4	-0.2	-1.0	-0.7	-1.4
Eye problems/disorders: None of the above	0.7	0.8	1.5	-0.9	-0.6	-1.2	-0.3	-1.2	-0.6	-1.0	-1.2	-0.5	-0.8	-0.6
Average weekly beer plus cider intake	0.7	1.0	6.1	-0.6	1.1	0.3	-0.5	-1.4	-0.1	-2.5	0.8	-0.5	0.7	-0.4
Bipolar Disorder (2018)	0.6	0.9	2.2	-0.0	1.4	1.4	-0.0	0.6	1.4	0.5	1.5	-0.1	0.9	0.7
Depressed Affect (Nagel 2018)	0.6	1.2	2.9	-0.9	-0.0	-0.6	-1.7	-1.2	-0.4	-1.6	-0.8	-1.4	-0.8	-1.4
Schizophrenia (2018)	0.6	1.3	6.0	-2.4	0.2	0.0	-0.3	-0.9	1.5	1.7	-0.4	-0.3	-1.2	-0.2
Verbal and Numeric Reasoning (VNR)	0.6	1.4	3.9	-0.0	-0.8	-0.0	1.8	1.5	-1.1	1.2	0.5	2.0	0.5	1.6
Body Mass Index (BMI) (2010)	0.6	0.9	2.6	1.6	-0.5	0.5	0.7	1.3	0.9	0.7	1.0	1.0	1.0	0.3
Vitamin and mineral supplements	0.6	0.8	2.3	-0.7	0.9	0.6	-1.3	-0.9	-1.1	0.3	-0.3	-1.5	-0.7	-0.9
Trunk fat percentage	0.6	2.4	6.0	-0.2	0.2	-0.2	-2.1	-1.4	-2.5	0.1	-1.3	-2.2	-1.9	-2.1
Medication: Ramipril	0.6	0.7	2.1	0.4	0.6	0.7	0.7	0.7	0.5	0.4	1.5	0.8	1.4	0.9
Arm fat percentage (right)	0.6	2.4	6.2	0.1	-0.3	-0.6	-1.9	-1.2	-2.5	0.5	-1.4	-2.1	-1.9	-2.1
Trunk fat-free mass	0.6	3.3	8.1	2.8	-2.8	-1.8	1.8	2.3	1.1	1.6	0.4	2.0	0.7	0.5
Trunk predicted mass	0.6	3.3	7.8	2.8	-2.8	-1.8	1.8	2.3	1.1	1.7	0.4	2.0	0.6	0.5
Tense / ‘highly strung’	0.6	1.0	4.4	-2.1	1.8	1.0	-0.2	-1.1	0.6	-0.9	0.1	-0.2	-0.0	0.5
Number of children fathered	0.6	0.7	4.4	-0.1	-1.0	-0.5	-0.1	0.3	-0.3	2.1	-0.5	-0.0	-1.0	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.8	-0.3	-0.8	-1.1	1.4	0.6	-0.8	-0.2	-0.6	1.2	0.0	0.9
Medication: Ibuprofen	0.6	0.8	2.4	0.1	1.5	1.4	-0.8	0.2	0.8	-0.3	1.3	-0.9	0.6	0.0
Mean time to correctly identify matches	0.6	1.2	3.1	-1.1	-0.5	-0.8	-1.7	-1.5	-0.9	-0.0	-0.7	-1.3	-1.2	-1.3
Smoking status: Previous	0.6	1.0	3.1	-1.8	0.8	0.1	-1.3	-1.4	-0.6	-0.7	-0.2	-1.1	-0.6	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.1	2.6	0.4	-0.6	-0.1	1.5	1.3	0.9	1.6	0.8	1.6	0.5	1.3
Whole body fat-free mass	0.6	3.7	10.0	3.2	-2.9	-1.8	1.8	2.6	0.9	1.8	0.5	2.0	0.6	0.4
Commuting to job workplace: Walk	0.6	0.7	3.3	1.8	0.8	1.2	-0.6	0.8	0.4	-0.1	0.7	-0.5	0.4	-0.2
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	3.1	1.0	0.9	1.6	-0.4	0.4	0.5	0.1	1.8	-0.3	1.3	0.4
Whole body water mass	0.6	3.5	9.9	3.1	-2.9	-1.8	1.6	2.5	0.9	1.9	0.4	1.9	0.6	0.4
Miserableness	0.6	1.0	2.5	-0.4	-0.4	-0.7	-1.5	-1.1	-0.3	-1.1	-0.7	-1.2	-0.9	-1.6
Medication: Blood pressure	0.6	1.2	4.4	0.2	0.0	0.2	-2.0	-0.9	-0.8	-0.1	-0.2	-2.1	-0.5	-1.6
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.5	-1.0	-0.3	-0.6	-0.9	-0.6	-1.0	0.4	-0.8	-1.0	-1.2	-1.0
Age started oral contraceptive pill	0.6	0.8	2.7	0.8	-1.6	-1.0	1.1	1.2	-0.6	0.6	-0.5	0.9	0.1	0.5
Vascular/heart problems diagnosed by doctor	0.6	1.6	4.1	-0.7	-1.4	-1.7	0.0	-0.6	-2.0	0.5	-2.0	-0.0	-1.8	-0.7
Bipolar Disorder or Schizophrenia	0.5	1.2	4.0	-1.9	1.1	0.9	-0.3	-0.4	2.0	1.7	0.6	-0.3	-0.3	0.2
Coronary Artery Disease (CAD)	0.5	0.6	2.2	0.7	1.5	1.0	-0.1	0.2	1.2	-1.0	-0.2	-0.0	0.1	0.5
Blood White Count	0.5	4.1	19.0	4.4	-2.6	-0.3	-0.4	2.0	3.0	0.4	1.5	-0.3	1.7	-0.9
Relative age of first facial hair	0.5	0.9	5.0	-0.7	-0.1	-0.6	-0.1	-0.1	-2.2	0.7	-1.5	-0.4	-1.1	-0.5
Diabetes (father)	0.5	0.6	2.9	-0.8	1.7	1.1	-0.3	-0.7	0.3	-0.3	0.5	-0.6	0.7	0.4
Sitting height	0.5	3.7	6.6	2.4	-2.5	-1.6	2.3	2.5	1.8	1.8	0.2	2.6	0.6	1.3
Hearing difficulty/problems with background noise	0.5	0.9	5.9	-2.4	-0.5	-0.9	0.1	-0.9	-0.5	0.1	-1.1	0.3	-0.6	0.1
Hair/balding pattern: Pattern 2	0.5	0.6	2.0	0.4	0.9	1.1	-0.1	0.4	1.0	-0.0	1.4	0.3	0.9	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	2.9	-1.0	0.5	0.0	-1.7	-0.7	-0.8	0.8	-0.7	-1.6	-1.3	-1.2
Neuroticism score	0.5	1.0	3.5	-0.6	1.3	0.9	-1.3	-0.8	0.7	-1.9	0.2	-1.3	0.2	-0.7
Impedance of arm (right)	0.5	2.5	8.7	-3.0	2.1	0.9	-1.0	-2.4	-1.0	-1.0	-1.1	-1.2	-1.4	0.0
Father’s age at death	0.5	0.7	4.4	2.1	-1.1	-0.4	-0.1	0.8	0.4	0.7	0.1	-0.1	0.1	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.7	-1.6	0.3	-0.4	-0.9	-1.3	-0.6	0.1	-0.8	-0.7	-1.0	-0.8
Exposure to tobacco smoke outside home	0.5	0.7	2.1	0.6	-1.3	-1.5	0.8	0.6	-0.3	-0.5	-0.9	0.8	-0.4	0.2
Heart disease (mother)	0.5	0.7	2.0	-0.7	0.4	0.8	-1.4	-0.8	-0.5	-0.6	0.3	-1.3	-0.4	-0.8
Arm predicted mass (right)	0.5	2.3	7.3	2.7	-2.5	-1.6	1.1	2.1	0.6	1.2	0.2	1.4	0.4	-0.1
Chest pain or discomfort	0.5	0.7	3.5	-0.8	0.3	-0.1	0.7	-1.2	0.3	-1.9	0.7	0.8	0.6	0.6
Family relationship satisfaction	0.5	0.6	2.0	0.3	-0.5	-0.7	1.4	0.2	-0.9	0.0	-0.3	1.3	0.4	1.0
Illnesses of siblings: Diabetes	0.5	0.6	1.5	-1.2	0.3	-0.2	-0.8	-0.6	0.1	0.7	-0.9	-1.2	-0.9	-0.7
Arm fat percentage (left)	0.5	1.9	4.6	0.5	-0.2	-0.3	-1.8	-1.0	-2.1	0.4	-1.1	-2.0	-1.6	-2.0
Guilty feelings	0.5	0.7	3.1	1.1	-0.9	-0.5	0.4	1.2	1.8	-0.3	0.3	0.7	0.4	-0.2
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.6	-1.6	0.3	-0.6	-0.4	-1.1	-0.5	-0.3	-0.8	-0.5	-0.8	-0.3
Basal metabolic rate	0.5	2.8	9.0	3.0	-2.6	-1.6	1.3	2.3	0.7	1.7	0.4	1.5	0.4	0.1
Leg fat mass (left)	0.5	1.8	4.1	0.3	-0.5	-0.5	-1.9	-0.9	-2.0	0.0	-1.0	-1.9	-1.6	-2.0
Alzheimer’s Disease (including proxy)	0.4	0.6	2.0	-0.4	1.4	0.8	0.4	0.2	0.5	-1.2	0.6	0.6	0.8	1.0
Neuroticism (2016)	0.4	0.5	0.9	0.6	-1.0	-0.9	-0.9	0.2	-0.2	-0.4	-1.0	-0.8	-0.5	-0.9
Neuroticism	0.4	0.9	2.3	-1.4	-0.3	-0.5	-1.1	-1.2	0.4	-1.5	-0.4	-0.9	-0.5	-1.1
Sensitivity / hurt feelings	0.4	0.7	2.0	0.9	-0.2	-0.3	-1.0	-0.2	0.3	-0.7	-1.0	-1.4	-0.6	-1.3
Hearing difficulty/problems: Yes	0.4	0.7	1.9	-1.4	0.1	-0.0	-1.2	-0.9	-0.8	-0.5	-0.2	-1.1	-0.4	-0.9
Fed-up feelings	0.4	0.6	2.0	-0.7	0.5	0.5	-1.4	-0.9	0.3	-1.0	0.1	-1.2	-0.2	-0.9
Nervous feelings	0.4	0.7	5.2	-2.3	0.4	0.3	-0.4	-0.9	-0.5	-0.2	-0.4	-0.2	-0.6	0.2
Hair/balding pattern: Pattern 3	0.4	0.6	3.5	-1.1	-0.2	0.1	0.7	0.3	0.6	1.9	0.0	0.7	-0.5	0.5
Happiness	0.4	0.5	1.2	0.2	-0.7	-0.8	1.0	0.1	-1.0	-0.0	-0.3	1.1	0.9	0.7
Illnesses of mother	0.4	0.5	2.1	0.1	-1.3	-1.5	0.7	-0.1	-0.5	0.2	-0.9	0.4	-0.4	-0.1
Pulse wave Arterial Stiffness index	0.4	0.5	2.0	1.4	-1.1	-0.7	-0.4	-0.1	-0.4	0.7	-0.4	-0.4	-0.6	-0.9
Impedance of arm (left)	0.4	1.7	4.8	-2.2	2.1	1.1	-0.8	-2.0	-0.7	-1.1	-0.6	-0.9	-0.8	0.2
Arm fat mass (right)	0.4	1.5	3.3	1.0	-1.0	-0.9	-1.3	-0.4	-1.7	0.8	-1.0	-1.4	-1.4	-1.8
Length of working week for main job	0.4	0.5	1.6	0.3	0.4	0.3	1.1	0.5	0.4	-0.3	0.5	1.3	0.8	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.6	-1.0	1.0	0.4	-0.3	-0.6	0.6	-1.6	0.1	-0.3	0.7	0.3
High blood pressure (siblings)	0.4	0.6	2.5	1.6	-0.0	-0.0	0.5	1.4	0.6	-0.2	0.4	0.5	0.8	0.4
Arm fat-free mass (right)	0.4	2.1	6.8	2.4	-2.6	-1.8	0.8	1.8	0.4	1.5	0.1	1.0	0.1	-0.4
Pulse wave peak to peak time	0.4	0.4	1.9	-1.4	0.8	0.4	0.5	0.2	0.3	-0.5	0.3	0.5	0.5	0.9
Emphysema/chronic bronchitis	0.4	0.4	1.0	-0.3	-0.7	-0.3	-1.0	-0.4	0.2	0.3	-0.3	-0.9	-1.0	-0.9
Medication for pain relief, constipation, heartburn	0.4	0.6	1.8	-0.2	-1.0	-1.3	0.4	-0.6	-1.0	-0.6	-1.3	0.4	-0.6	0.2
Medication: Blood pressure	0.4	0.6	1.8	0.9	0.0	0.3	0.8	0.7	1.0	-0.4	1.2	0.7	1.3	0.6
Leg fat mass (right)	0.4	1.6	3.8	0.3	-0.3	-0.3	-1.9	-1.0	-1.7	-0.4	-0.8	-1.9	-1.3	-1.9
Suffer from ‘nerves’	0.4	0.6	1.4	-0.2	1.1	0.9	0.0	-0.5	1.2	-0.8	0.9	0.2	1.0	0.5
Knee pain experienced in last month	0.4	0.6	1.6	-0.7	-0.3	-0.4	-1.3	-0.9	-0.6	-0.0	-0.1	-1.1	-1.0	-1.1
Loneliness, isolation	0.4	0.6	1.8	0.4	1.3	1.2	-0.6	0.3	1.3	0.2	0.8	-0.3	0.5	0.0
Breast cancer (self-reported)	0.4	0.5	2.2	-0.7	0.0	0.1	-0.4	-0.2	-0.7	1.5	-0.2	-0.8	-0.8	-0.5
Osteoporosis (self-reported)	0.4	0.4	1.4	0.4	1.2	0.8	-0.9	0.2	0.4	-0.9	0.2	-0.7	-0.1	-0.5
Osteoarthritis (self-reported)	0.4	0.6	2.2	-1.3	0.2	-0.4	-0.2	-0.4	-1.5	0.7	-0.6	-0.2	-0.9	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	2.8	0.4	-0.6	-0.1	0.9	0.3	1.7	-0.6	1.0	1.0	1.6	1.0
Medication: Lisinopril	0.4	0.5	1.0	-1.0	0.0	-0.3	-1.0	-0.5	-0.9	0.8	-0.2	-0.9	-0.7	-0.8
Arm fat-free mass (left)	0.4	1.9	7.1	2.2	-2.7	-1.8	0.5	1.5	-0.1	1.6	-0.2	0.7	-0.3	-0.6
Diastolic blood pressure, automated reading	0.4	1.2	3.5	1.9	-1.2	-0.1	-1.4	0.9	-0.3	0.9	-0.1	-1.2	-0.4	-1.7
Unable to work because of sickness or disability	0.4	0.6	1.4	-0.5	0.8	0.4	-1.0	-1.0	0.5	-1.2	-0.2	-1.0	0.1	-0.6
Schizophrenia vs Biploar Disorder	0.3	0.3	1.1	-0.4	-1.0	-0.6	-0.1	0.1	-0.2	0.9	-0.4	0.1	-0.9	-0.4
Alzheimer’s Disease (in mother)	0.3	0.3	1.3	-1.1	0.2	-0.4	0.0	-0.4	-1.1	-0.6	-0.4	0.2	-0.1	0.2
Ulcerative Colitis (UC)	0.3	0.6	2.0	0.6	0.8	1.4	-0.7	0.6	0.9	-0.7	0.9	-0.5	0.3	-0.2
Rheumatoid Arthritis	0.3	0.5	1.2	-0.8	0.6	1.0	-0.7	-0.4	0.7	-0.4	1.1	-0.4	0.8	0.1
Ulcerative Colitis	0.3	0.5	1.4	0.3	0.6	1.1	0.1	0.6	1.2	-0.2	0.8	0.3	0.5	0.7
Heel T-Score	0.3	2.1	10.4	-1.2	3.2	2.6	-0.2	-0.5	0.7	-0.7	1.1	-0.3	0.5	1.2
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.8	1.4	0.0	0.4	0.6	1.0	0.3	1.3	0.6	0.4	0.3	0.6
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.9	-0.0	-0.9	-0.8	-0.5	0.2	-0.3	0.9	-0.6	-0.4	-0.7	-0.9
Systolic blood pressure, automated reading	0.3	1.0	2.8	-0.5	-0.5	-0.4	-1.4	-0.7	-1.7	-0.7	-0.8	-1.2	-0.8	-1.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.0	-0.0	0.5	0.3	0.7	0.4	0.4	1.0	0.5	0.6	0.2	0.7
Hayfever, allergic rhinitis or eczema	0.3	0.7	3.4	-1.8	0.8	-0.2	1.1	-0.5	-0.7	-0.2	-0.6	0.8	-0.3	0.7
Stomach or abdominal pain in last month	0.3	0.4	2.0	-1.4	0.8	0.0	-0.4	-1.0	0.5	-0.1	0.3	-0.0	0.2	0.3
Trunk fat mass	0.3	1.5	3.7	0.5	-0.5	-0.6	-1.5	-0.7	-1.9	0.4	-1.0	-1.5	-1.5	-1.8
Number of incorrect matches in round	0.3	0.6	2.5	-1.0	-0.8	-1.1	0.2	0.0	0.3	1.6	-0.2	0.6	-0.5	0.1
Had other major operations	0.3	0.3	1.0	-1.0	0.5	0.2	-0.6	-0.7	-0.2	-0.7	-0.3	-0.7	-0.2	-0.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.5	-1.2	0.5	-0.2	0.3	-0.2	-0.8	-0.4	-0.6	0.4	-0.5	0.6
Time employed in main current job	0.3	0.3	1.0	-0.1	0.3	-0.2	1.0	-0.3	-0.5	-0.7	-0.2	0.7	0.4	0.9
Number of live births	0.3	0.4	0.8	-0.7	0.6	0.9	-0.8	-0.6	0.5	0.6	0.7	-0.6	0.2	-0.2
Depression (self-reported)	0.3	0.4	1.2	-1.1	0.5	0.7	-0.5	0.3	0.2	1.0	0.5	-0.4	-0.0	-0.2
Breastfed as a baby	0.3	0.4	1.5	0.2	0.4	0.9	-0.4	-0.1	0.1	-1.0	0.4	-0.4	1.2	0.0
Hair/balding pattern: Pattern 4	0.3	0.8	1.6	-0.1	-0.9	-0.8	-1.0	-0.4	-0.7	-0.5	-1.2	-1.2	-0.7	-1.1
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.0	0.3	0.4	0.3	0.8	0.2	0.9	-0.7	0.5	1.0	0.6	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	2.2	-1.5	0.5	-0.0	-0.3	-0.8	-0.4	0.1	-0.6	-0.4	-0.4	-0.1
Whole body fat mass	0.3	1.3	3.0	0.8	-0.5	-0.5	-1.5	-0.5	-1.7	0.3	-0.7	-1.5	-1.3	-1.7
Pulse rate, automated reading	0.3	1.0	3.5	0.8	1.6	1.9	-1.3	0.1	0.2	-0.1	0.7	-1.3	0.3	-0.7
Leg pain on walking	0.3	0.4	1.2	0.0	-0.4	-0.6	1.1	-0.1	0.5	-0.1	0.1	1.1	0.7	0.5
Arm fat mass (left)	0.3	1.2	2.9	1.2	-0.9	-0.7	-1.2	-0.3	-1.5	0.7	-0.7	-1.3	-1.1	-1.7
Medication: Atorvastatin	0.3	0.3	1.1	0.7	0.0	-0.1	0.5	0.4	0.2	-1.1	0.2	0.4	1.1	0.5
Number of operations (self-reported)	0.3	0.4	2.6	-1.6	0.5	0.2	-0.5	-0.5	0.1	0.4	-0.6	-0.8	-0.3	-0.4
Fractured/broken bones in last 5 years	0.3	0.4	2.0	-1.4	0.6	0.0	-0.1	-0.9	-1.0	-0.0	-0.4	-0.0	-0.7	0.1
Cholesterol lowering medication	0.3	0.4	1.1	-0.2	-0.6	-0.8	-0.0	-0.5	-0.7	1.1	-0.8	-0.4	-0.4	-0.6
Arm predicted mass (left)	0.3	1.8	6.5	2.0	-2.5	-1.7	0.5	1.4	-0.0	1.6	-0.2	0.7	-0.3	-0.6
Neuroticism (Nagel 2018)	0.2	0.5	2.2	-1.5	0.0	-0.4	-0.6	-1.0	0.6	-0.5	-0.6	-0.5	-0.4	-0.5
Breast Cancer	0.2	0.6	1.5	0.8	-0.9	-1.2	0.6	-0.1	0.4	-1.2	-0.7	0.8	0.6	0.3
Ovarian Cancer	0.2	0.2	0.5	-0.6	-0.5	-0.6	-0.3	-0.0	-0.7	0.5	-0.5	-0.2	-0.4	-0.4
HDL Cholesterol	0.2	0.3	1.3	0.0	0.4	-0.2	1.1	0.4	0.0	-0.1	-0.3	0.6	0.2	1.1
LDL Cholesterol	0.2	0.4	1.0	0.3	-0.1	0.2	1.0	0.6	0.2	0.2	0.5	0.8	0.8	1.0
Blood Platelet Count	0.2	2.6	7.5	-0.7	-1.4	-2.1	-0.7	-1.2	-2.0	-1.3	-2.7	-0.8	-1.9	-1.4
BMI	0.2	1.0	5.5	2.3	-1.2	-0.9	-0.5	0.7	-0.8	0.4	-0.4	-0.6	-0.3	-1.1
Lung FEV1/FVC ratio	0.2	1.1	3.3	1.8	-0.4	-0.1	1.5	1.1	1.1	0.1	0.7	1.4	1.1	1.0
Hand grip strength (left)	0.2	0.6	2.5	1.5	0.2	0.3	-0.6	0.3	0.8	-1.6	0.6	-0.4	0.5	-0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.9	0.9	-0.5	0.3	0.1	0.5	0.7	0.7	0.5	-0.0	0.4	-0.4
Medication: Co-codamol	0.2	0.2	0.6	-0.6	0.7	0.5	-0.2	0.1	-0.3	0.7	0.6	-0.2	0.2	-0.2
Medication: Metformin	0.2	0.3	1.7	-0.1	0.7	0.6	-0.5	0.1	-0.1	1.3	0.2	-0.6	-0.3	-0.1
Hand grip strength (right)	0.2	0.5	2.2	1.5	0.0	0.4	0.4	0.7	0.8	-0.6	0.8	0.4	0.6	0.2
Medication: Atenolol	0.2	0.2	0.6	-0.5	-0.4	-0.1	-0.6	-0.8	-0.3	-0.3	0.2	-0.7	-0.0	-0.4
Body mass index (BMI)	0.2	0.9	2.2	1.5	-0.9	-0.6	-1.0	0.0	-1.1	0.4	-0.3	-1.0	-0.5	-1.5
Waist circumference	0.2	0.7	2.1	0.9	-0.4	-0.2	-1.3	-0.1	-0.9	0.3	-0.3	-1.3	-0.7	-1.5
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.4	2.2	0.3	0.5	0.1	-0.1	0.1	0.8	-1.5	0.3	0.2	0.7	0.0
Weight	0.2	1.0	3.3	1.8	-1.6	-1.1	-0.1	0.9	-0.5	1.1	-0.2	0.1	-0.5	-0.8
Worrier / anxious feelings	0.2	0.4	1.7	-1.3	0.1	-0.4	-0.8	-0.5	-0.4	-0.0	-0.7	-0.7	-0.9	-0.6
Pulse rate	0.2	0.3	1.2	1.0	-0.4	0.2	-0.2	0.6	-0.3	1.1	0.4	-0.2	-0.1	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.5	-0.0	0.6	0.6	-0.7	0.0	0.1	0.5	0.6	-0.7	0.0	-0.3
Standing height	0.2	2.1	5.0	1.2	-1.4	-0.9	1.9	1.9	1.4	1.5	0.4	2.2	0.3	1.4
Loud music exposure frequency	0.2	0.3	1.6	0.2	0.3	0.1	-0.5	0.2	0.2	1.3	-0.1	-0.7	-0.4	-0.4
Headache pain in last month	0.2	0.3	0.9	-0.9	-0.1	-0.6	0.1	-0.5	-0.8	0.6	-0.9	0.0	-0.8	0.0
Comparative body size at age 10	0.2	0.7	4.1	2.0	-0.6	-0.6	0.5	0.8	-0.5	-0.7	0.2	0.5	0.6	0.1
Medication: Allopurinol	0.2	0.2	1.1	-0.2	-1.1	-0.6	0.1	0.1	0.2	0.7	0.0	0.2	-0.3	-0.2
Comparative height size at age 10	0.2	1.3	5.8	-0.1	-2.4	-2.0	-0.6	-0.3	0.0	0.3	-1.0	-0.0	-1.3	-1.1
Supplements: Vitamin C	0.2	0.2	0.6	0.5	-0.5	-0.0	0.5	0.4	0.8	-0.4	0.3	0.7	0.6	0.4
Hearing aid user	0.2	0.2	0.8	0.4	0.1	-0.2	-0.1	0.9	0.7	-0.4	0.2	0.2	0.1	-0.3
Mother’s age at death	0.2	0.3	1.7	0.7	-0.2	-0.1	-0.4	0.7	0.1	1.3	0.4	-0.0	-0.1	-0.4
Financial situation satisfaction	0.2	0.2	0.5	0.4	-0.7	-0.6	-0.0	-0.3	-0.5	-0.5	-0.6	-0.1	0.2	-0.3
High cholesterol (Self-reported)	0.2	0.3	1.0	-1.0	0.9	0.5	-0.3	-0.5	-0.4	0.8	0.1	-0.5	-0.1	-0.2
Medication: Bendroflumethiazide	0.2	0.2	2.0	1.4	0.0	0.0	0.1	0.3	-0.2	-0.1	0.2	-0.1	0.6	0.1
Myopia	0.2	0.4	2.2	-0.0	-0.7	-0.6	0.5	-0.4	-0.2	-1.5	-0.5	0.1	0.3	0.2
Supplements: Calcium	0.2	0.2	0.6	0.2	0.6	0.8	-0.0	0.5	0.7	-0.3	0.2	-0.2	0.6	0.0
Heart attack/myocardial infarction (self-reported)	0.2	0.3	1.0	-0.7	-0.2	-0.1	0.5	0.5	1.0	-0.2	0.3	0.5	0.7	0.1
Blood Red Count	0.1	1.1	4.8	-0.2	-0.1	-0.3	0.3	-1.8	-1.8	-2.2	-1.0	0.0	-0.2	0.0
Height	0.1	1.5	3.3	0.7	-1.4	-0.9	1.6	1.6	0.6	1.8	-0.2	1.8	-0.2	0.8
Systolic Blood Pressure	0.1	0.5	2.4	-1.6	0.7	0.0	-0.3	-1.2	-0.7	-1.0	0.0	-0.1	0.0	0.2
Ever had hysterectomy (womb removed)	0.1	0.1	0.3	0.2	-0.5	-0.2	-0.1	-0.0	-0.2	0.5	-0.0	-0.3	-0.2	-0.4
Age when periods started (menarche)	0.1	0.3	1.0	-0.8	0.8	0.1	0.6	-0.5	-0.1	0.5	0.0	0.6	-0.3	1.0
High blood pressure	0.1	0.4	0.8	0.1	0.5	0.7	-0.9	-0.4	0.7	-0.3	0.8	-0.9	0.4	-0.5
Heart attack	0.1	0.2	0.7	-0.8	-0.3	-0.1	0.3	0.3	0.7	-0.2	0.2	0.3	0.6	-0.0
Hip circumference	0.1	0.5	2.2	1.4	-0.5	-0.0	0.1	1.1	-0.2	1.5	0.5	0.2	-0.1	-0.2
Peak expiratory flow (PEF)	0.1	0.2	0.6	-0.2	-0.3	-0.3	0.8	0.2	0.6	-0.2	0.3	0.7	0.6	0.6
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.4	0.5	0.1	0.0	-0.0	0.0	0.2	0.7	-0.1	-0.2	-0.4	-0.1
Medication: Paracetamol	0.1	0.2	0.7	-0.3	0.2	0.2	-0.5	-0.4	-0.9	-0.1	0.2	-0.7	-0.3	-0.7
Worry too long after embarrassment	0.1	0.2	0.6	-0.3	0.6	0.7	-0.4	0.2	0.8	0.7	0.4	-0.4	0.0	-0.2
Had major operations	0.1	0.2	0.4	-0.5	0.2	0.5	-0.4	0.3	0.4	0.6	-0.1	-0.5	0.3	-0.2
Hypertension (Self-reported)	0.1	0.2	0.8	0.2	0.2	0.5	-0.6	-0.1	0.7	0.1	0.9	-0.5	0.3	-0.2
Mood swings	0.1	0.2	1.0	0.6	-0.3	-0.6	0.0	0.4	0.3	-1.0	-0.2	0.0	0.3	-0.4
Friendships satisfaction	0.1	0.2	0.8	-0.7	0.1	-0.4	-0.2	-0.3	-0.9	0.2	-0.5	-0.0	0.0	0.0
Medication for cholesterol	0.1	0.2	0.7	-0.5	-0.0	-0.1	0.7	0.4	0.6	-0.0	-0.1	0.8	-0.1	0.6
Medication: Paracetamol	0.1	0.2	0.5	0.1	0.7	0.7	0.0	0.2	-0.2	-0.2	0.7	-0.1	0.3	0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Cardiovascular Disease	0.0	0.2	0.4	-0.6	0.2	0.2	0.4	-0.4	0.4	-0.2	0.5	0.3	0.2	0.5
Hair Pigment	0.0	0.7	2.1	1.2	0.3	0.6	-1.1	-0.6	-1.1	-0.1	0.2	-1.5	0.0	-0.9
Tanning	0.0	0.6	1.5	0.8	-1.2	-0.8	-0.3	0.4	-0.7	-0.7	-1.1	-0.5	-0.7	-0.6

Hub : Genes

RARS2

Models

Trait associations