TWAS hub - RASGEF1B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Cerebellar Hemisphere	0.3040	0.0870	0.00011	0.303	NA	0.259	NA	0.308	1.7e-08	NA	2.5e-07	NA	1.2e-08
2	METSIM	Adipose	0.0434	0.0174	0.00480	-0.001	0.014	-0.001	0.013	-0.002	4.9e-01	0.0032	4.4e-01	0.0036	7.7e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Ever had hysterectomy (womb removed)	5.1	5.7	6.0	2.3	2.4
Diabetes (father)	4.8	5.9	11.8	3.4	0.3
Alzheimer’s Disease (in father)	4.4	4.7	9.3	-3.0	-0.5
Qualifications: None of the above	4.2	9.1	11.7	3.4	2.5
Mouth/teeth dental problems: Dentures	3.7	6.2	9.2	3.0	1.8
Ever unenthusiastic/disinterested for a whole week	3.3	4.0	4.8	-2.2	-1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.3	4.0	8.0	2.8	0.2
Medication: Ibuprofen (e.g. Nurofen)	3.0	3.8	6.8	-2.6	-0.9
Qualifications: O levels/GCSEs or equivalent	3.0	4.8	6.5	-2.6	-1.8
Medication: Ibuprofen	3.0	3.5	7.1	-2.7	0.0
Alzheimer’s Disease (including proxy)	2.7	3.9	7.5	-2.7	-0.6
Medication: Gliclazide	2.7	3.0	5.0	2.2	1.0
Chronic bronchitis/emphysema (father)	2.6	3.1	5.1	1.0	2.3
Waist circumference	2.6	9.7	17.9	4.2	1.2
Medication: Paracetamol	2.6	4.0	6.5	1.2	2.5
Risk taking	2.6	3.8	6.6	-2.6	-1.0
Ever depressed for a whole week	2.6	3.2	6.1	-2.5	-0.5
Fasting Glucose	2.5	3.0	5.7	0.4	2.4
Alcohol intake versus 10 years previously	2.5	3.7	6.4	1.0	2.5
Fractured/broken bones in last 5 years	2.5	3.3	6.4	0.5	2.5
Myopia	2.5	3.6	5.6	1.2	2.4
Medication: Seretide 50 evohaler	2.4	2.8	3.7	-1.4	-1.9
Guilty feelings	2.4	3.6	6.3	-2.5	-1.0
Loud music exposure frequency	2.3	2.5	3.2	1.8	1.3
Medication: Paracetamol	2.3	3.9	5.8	1.4	2.4
Exposure to tobacco smoke outside home	2.3	3.1	5.8	0.6	2.4
Neck or shoulder pain in last month	2.3	3.2	4.6	-1.4	2.1
Arm fat mass (left)	2.3	9.4	15.9	4.0	1.7
Pack years of smoking	2.3	3.3	3.4	1.8	1.9
Diabetes (mother)	2.2	2.8	5.2	2.3	0.5
Reason for reducing amount of alcohol drunk: Health precaution	2.2	2.5	4.2	0.9	2.1
Osteoarthritis (self-reported)	2.2	2.8	4.2	1.2	2.0
Body Mass Index (BMI) (2010)	2.1	2.9	3.5	1.5	1.9
Mean Putamen Volume	2.1	2.3	4.5	-2.1	-0.5
Trunk fat mass	2.1	9.2	13.3	3.6	2.3
Leg fat percentage (right)	2.1	7.6	14.8	3.8	0.6
Whole body fat mass	2.1	8.7	13.8	3.7	1.9
Alcohol drinker status: Previous	2.1	2.4	3.7	1.0	1.9
Ovarian Cancer	2.0	2.6	5.2	-0.1	-2.3
Age at First Birth	2.0	2.9	3.4	-1.8	-1.5
Relative age voice broke	2.0	3.0	5.6	-0.6	-2.4
Hayfever/allergic rhinitis (self-reported)	2.0	2.7	4.1	-2.0	1.1
Weight	2.0	9.7	12.0	3.5	2.7
Overall health rating	2.0	4.3	7.4	1.1	2.7
Major Depression (MDD)	1.9	2.3	3.5	1.0	-1.9
Neuroticism	1.9	4.6	5.1	-2.0	-2.3
Average weekly fortified wine intake	1.9	2.2	4.3	-0.2	-2.1
Neuroticism score	1.9	4.1	6.1	-2.5	-1.4
Hair/balding pattern: Pattern 3	1.9	2.9	4.8	-1.0	-2.2
Arm fat mass (right)	1.9	7.7	13.9	3.7	1.3
Body fat percentage	1.9	7.6	14.4	3.8	1.0
Leg fat mass (right)	1.9	7.3	12.7	3.6	1.4
Alcohol intake frequency.	1.9	4.4	7.2	1.3	2.7
Leg fat percentage (left)	1.9	6.8	13.2	3.6	0.6
Chronotype (morning person)	1.8	4.3	6.5	-1.4	-2.5
Pack years adult smoking proportion	1.8	2.8	3.2	1.5	1.8
Trunk fat percentage	1.8	7.1	12.6	3.6	1.3
Maternal smoking around birth	1.8	2.5	3.2	1.4	1.8
Arm fat percentage (left)	1.8	7.2	14.3	3.8	0.1
Average weekly red wine intake	1.8	2.7	3.7	-1.9	-1.3
Diabetes diagnosed by doctor	1.8	3.0	6.0	2.5	0.0
Arm fat-free mass (left)	1.8	9.0	14.1	2.0	3.8
Leg fat mass (left)	1.8	6.9	11.8	3.4	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.2	2.6	-1.4	-1.6
High blood pressure	1.7	4.7	6.3	1.8	-2.5
Diabetes (self-reported)	1.7	2.7	4.9	2.2	0.7
Hip circumference	1.7	7.3	11.8	3.4	1.7
Depression (self-reported)	1.7	2.0	3.8	0.3	-2.0
Arm fat-free mass (right)	1.7	8.8	14.7	1.7	3.8
Eye problems/disorders: None of the above	1.7	1.9	2.0	-1.4	-1.4
Arm predicted mass (right)	1.7	8.9	15.7	1.5	4.0
Arm predicted mass (left)	1.7	8.7	14.3	1.7	3.8
Hearing difficulty/problems: Yes	1.6	2.4	3.3	1.2	1.8
Arm fat percentage (right)	1.6	6.3	12.6	3.6	0.0
Noisy workplace	1.6	2.0	3.7	0.4	1.9
Standing height	1.6	15.7	31.4	-0.2	5.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.4	2.6	-1.6	-1.5
Basal metabolic rate	1.6	8.7	12.5	2.2	3.5
Cholesterol lowering medication	1.6	2.3	4.4	2.1	-0.5
Body mass index (BMI)	1.5	6.4	12.8	3.6	0.2
Hair/balding pattern: Pattern 2	1.5	1.9	3.5	0.6	1.9
Number of live births	1.5	2.1	2.4	1.6	1.3
Shortness of breath walking on level ground	1.5	1.8	2.6	-1.0	-1.6
Hypertension (Self-reported)	1.5	4.1	4.6	1.9	-2.1
Whole body fat-free mass	1.5	8.3	13.7	1.7	3.7
Whole body water mass	1.5	8.4	14.0	1.7	3.7
Mother’s age at death	1.5	1.9	3.7	-0.3	-1.9
Supplements: Calcium	1.5	1.6	2.7	-0.7	1.7
Heart disease (siblings)	1.5	1.9	3.5	-1.9	-0.5
Height	1.4	27.9	55.7	-0.3	7.5
Trunk fat-free mass	1.4	8.2	14.7	1.3	3.8
Worrier / anxious feelings	1.4	2.7	5.0	-2.2	-0.7
Trunk predicted mass	1.4	8.3	14.9	1.3	3.9
Glaucoma (self-reported)	1.4	1.7	3.4	0.1	1.8
High cholesterol (Self-reported)	1.4	2.5	4.5	0.7	-2.1
Commuting to job workplace: Cycle	1.4	1.7	1.9	-1.4	-1.2
Cardiovascular Disease	1.3	4.2	8.2	0.5	-2.9
Medication: Metformin	1.3	1.8	3.5	1.9	-0.2
Stomach or abdominal pain in last month	1.3	1.7	1.9	1.2	1.4
Sitting height	1.3	9.0	17.9	-0.4	4.2
Leg predicted mass (left)	1.3	6.6	8.9	2.1	3.0
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.6	4.9	-0.6	2.2
Medication: Atorvastatin	1.3	1.6	2.2	-1.0	-1.5
Vascular/heart problems diagnosed by doctor	1.3	3.5	5.2	-1.3	2.3
Leg fat-free mass (left)	1.2	6.4	8.8	2.0	3.0
Bilateral oophorectomy (both ovaries removed)	1.2	1.3	1.7	1.0	1.3
Had menopause	1.2	1.4	2.7	1.6	0.4
Medication: Simvastatin	1.2	1.8	3.0	0.8	-1.7
Breast cancer (self-reported)	1.2	1.4	2.2	-1.5	0.8
Average weekly beer plus cider intake	1.2	1.7	3.4	-0.2	-1.9
Schizophrenia vs Biploar Disorder	1.1	1.4	2.5	0.5	1.6
Coronary Artery Disease (CAD)	1.1	1.3	1.8	-0.9	-1.3
Supplements: Zinc	1.1	1.2	1.8	-1.3	0.8
Fed-up feelings	1.1	2.0	3.1	-0.9	-1.8
Nervous feelings	1.1	2.0	3.6	-0.6	1.9
Financial difficulties in last 2 years	1.1	1.5	3.1	-1.8	0.0
Emphysema/chronic bronchitis	1.1	1.2	2.5	-0.0	1.6
Mean time to correctly identify matches	1.1	2.1	3.4	1.8	0.9
Number of full sisters	1.1	1.3	1.7	0.9	1.3
Ulcerative Colitis	1.0	1.4	1.4	1.2	-1.2
Smoking Status	1.0	2.5	3.3	1.8	-1.3
Hand grip strength (right)	1.0	2.6	4.3	-0.9	-2.1
Pulse wave reflection index	1.0	1.3	2.1	-0.6	-1.5
Qualifications: College or University degree	1.0	3.1	3.9	-1.5	-2.0
Medication: Allopurinol	1.0	1.3	1.8	-1.4	0.9
Leg fat-free mass (right)	1.0	5.5	8.4	1.6	2.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.0	1.2	2.3	1.5	0.0
Leg predicted mass (right)	1.0	5.1	7.7	1.6	2.8
Depressed Affect (Nagel 2018)	0.9	2.0	3.7	-0.4	-1.9
Medication: Ramipril	0.9	1.1	1.9	0.6	-1.4
Comparative height size at age 10	0.9	4.9	8.5	-1.1	2.9
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	1.6	-1.1	-1.3
Depression (Nagel 2018)	0.8	1.2	2.4	0.2	-1.6
Type 2 Diabetes (T2D) (2018)	0.8	1.5	2.6	1.6	-0.6
Sensitivity / hurt feelings	0.8	1.4	1.8	-1.4	-1.0
Medication: Co-codamol	0.8	1.0	1.8	0.4	1.3
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	2.0	1.4	0.1
Medication: Levothyroxine sodium	0.8	1.3	2.2	-0.6	1.5
High blood pressure (mother)	0.8	1.1	1.2	1.1	-1.0
Alcohol usually taken with meals	0.8	1.4	2.5	-1.6	0.5
Hearing difficulty/problems with background noise	0.8	1.3	2.5	1.6	0.4
Blood clot in the leg (DVT)	0.8	1.0	1.9	1.4	-0.3
Headache pain in last month	0.8	1.3	2.7	-1.6	0.1
Forced vital capacity (FVC), Best measure	0.8	2.8	5.5	0.4	2.3
Pulse wave peak to peak time	0.8	0.9	1.1	0.9	1.1
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	2.0	1.4	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	1.5	0.5	-1.2
Illnesses of siblings: Diabetes	0.8	1.0	1.6	1.3	-0.6
Long-standing illness, disability or infirmity	0.8	1.2	1.3	1.1	1.1
Medication for cholesterol	0.8	1.2	1.3	-1.0	1.2
Average weekly champagne plus white wine intake	0.8	1.2	1.2	-1.1	1.1
Eye problems/disorders: Glaucoma	0.8	0.9	1.3	-1.1	0.7
Diastolic blood pressure, automated reading	0.8	2.4	4.8	-0.3	-2.2
Alzheimer’s Disease (in mother)	0.7	0.8	1.4	-1.2	-0.4
Primary Biliary Cirrhosis	0.7	1.0	1.2	0.8	-1.1
BMI	0.7	4.2	8.3	2.9	0.3
Hand grip strength (left)	0.7	1.9	1.9	-1.4	-1.4
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.2	0.5	1.1
Forced vital capacity (FVC)	0.7	2.8	5.4	-0.3	2.3
Father’s age at death	0.7	0.9	1.9	1.4	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	4.5	0.2	2.1
Hair/balding pattern: Pattern 4	0.7	1.7	1.7	-1.3	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	1.6	-1.2	0.4
Miserableness	0.7	1.3	1.8	-0.9	-1.3
Medication: Lisinopril	0.7	0.9	1.5	0.5	-1.2
Ever smoked	0.7	1.3	2.1	1.4	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.8	1.3	-0.2
Neuroticism (Nagel 2018)	0.6	1.4	1.9	-1.0	-1.4
Breast Cancer	0.6	1.3	2.0	1.4	0.9
Bipolar Disorder (2011)	0.6	0.5	1.0	-1.0	-0.3
LDL Cholesterol	0.6	0.9	1.8	0.2	-1.3
Hypothyroidism (self reported)	0.6	1.5	1.7	1.1	1.3
Current tobacco smoking	0.6	1.0	1.9	1.4	-0.4
Had other major operations	0.6	0.7	0.9	0.9	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	1.5	-1.2	0.7
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	3.5	-0.5	1.9
Qualifications: A levels/AS levels or equivalent	0.6	1.3	2.1	-1.4	-0.7
Length of working week for main job	0.6	0.7	0.7	-0.8	0.8
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.4	-1.2	-0.4
Comparative body size at age 10	0.6	1.8	3.1	-0.6	-1.8
Wheeze or whistling in the chest in last year	0.6	1.0	1.7	-0.6	1.3
Knee pain experienced in last month	0.6	0.9	1.1	-0.8	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	1.4	-1.2	1.0
Commuting to job workplace: Public transport	0.6	0.8	1.1	-0.7	-1.0
Unable to work because of sickness or disability	0.6	0.8	0.9	-0.9	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.3	1.1	0.5
Bipolar Disorder (2018)	0.5	0.8	1.5	-0.3	1.2
Lupus	0.5	0.7	1.4	1.2	0.1
Blood White Count	0.5	3.6	6.2	2.5	1.0
Frequency of depressed mood in last 2 weeks	0.5	0.7	0.9	-1.0	-0.7
Severe depression (siblings)	0.5	0.6	1.1	-0.1	-1.1
Serious illness, injury or assault to yourself	0.5	0.7	1.1	-1.0	0.5
Hayfever, allergic rhinitis or eczema	0.5	1.2	2.3	-0.2	1.5
Multivitamins +/- minerals	0.5	0.7	1.4	-1.2	0.0
Past tobacco smoking	0.5	0.9	1.0	-1.0	0.9
Mouth/teeth dental problems	0.5	0.8	1.0	-1.0	-0.8
Falls in the last year	0.5	0.7	0.9	-1.0	0.7
Medication: Cholesterol lowering	0.5	0.8	1.3	-0.6	-1.2
Medication: Lansoprazole	0.5	0.6	1.2	-1.1	0.1
Prospective memory result	0.5	0.6	1.1	0.1	1.1
Exposure to tobacco smoke at home	0.5	0.6	0.9	-1.0	0.5
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.0	0.6	-1.0
Pulse rate, automated reading	0.5	1.5	2.3	0.8	1.5
Chest pain or discomfort	0.5	0.7	1.3	-0.3	1.1
Had major operations	0.5	0.6	0.9	-0.5	-1.0
Ever had bowel cancer screening	0.5	0.6	0.9	1.0	0.5
Eye problems/disorders: Cataract	0.5	0.5	0.8	0.9	0.5
Back pain experienced in last month	0.5	0.7	1.1	-1.1	-0.5
Illnesses of father: None of the above (group 1)	0.5	0.7	1.0	-1.0	0.6
Smoking status: Current	0.5	0.8	0.9	1.0	-0.9
Hearing aid user	0.5	0.6	0.9	1.0	0.5
Financial situation satisfaction	0.5	0.6	1.1	-1.1	-0.3
Medication: Blood pressure	0.5	0.9	1.6	0.5	-1.2
Medication: Bendroflumethiazide	0.5	0.7	0.8	0.8	0.9
Illnesses of father: High blood pressure	0.5	0.6	1.2	-0.2	-1.1
Number of operations (self-reported)	0.5	0.8	1.6	1.3	0.1
Ulcerative Colitis (UC)	0.4	0.7	1.3	0.2	-1.2
Reaction Time	0.4	0.7	1.4	1.2	-0.1
Neuroticism (2016)	0.4	0.6	0.7	0.9	-0.7
Type 2 Diabetes (T2D) (2012)	0.4	0.5	0.7	0.8	0.6
Allergy or Eczema	0.4	1.1	2.1	-0.3	1.4
Age when periods started (menarche)	0.4	0.8	1.7	-0.2	1.3
Allergy	0.4	0.8	1.6	-0.2	-1.2
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	0.5	-0.7	0.6
Lung cancer (father)	0.4	0.4	0.7	0.9	0.4
Pulse wave Arterial Stiffness index	0.4	0.5	0.7	-0.8	-0.6
Birth weight of first child	0.4	0.7	1.3	-0.3	1.1
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.0	-1.0	0.1
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.1	-0.5	1.0
Medication: Amlodipine	0.4	0.6	1.2	1.1	0.1
Medication: Blood pressure	0.4	0.8	0.9	1.0	-0.8
Friendships satisfaction	0.4	0.4	0.5	0.7	0.7
Ever taken oral contraceptive pill	0.4	0.4	0.9	-0.9	-0.1
Pain experienced in last month	0.4	0.7	0.9	1.0	-0.7
Irritable Bowel Disease (IBD)	0.3	0.8	1.0	1.0	-0.7
Prostate Cancer	0.3	0.4	0.6	-0.4	-0.8
HDL Cholesterol	0.3	0.5	1.0	1.0	0.1
Blood Eosinophil Count	0.3	2.6	3.3	1.8	-1.4
Blood Platelet Count	0.3	3.8	7.0	2.6	-0.7
Waist Hip Ratio (WHR)	0.3	1.3	2.0	1.4	-0.7
Lung FEV1/FVC ratio	0.3	1.5	2.7	-0.6	1.6
Systolic blood pressure, automated reading	0.3	0.7	1.4	1.2	0.1
Medication for hormone replacement therapy	0.3	0.3	0.6	-0.1	-0.8
Number of incorrect matches in round	0.3	0.5	1.0	0.0	1.0
Impedance of arm (right)	0.3	1.5	2.0	-1.4	-1.0
Pulse rate	0.3	0.5	0.8	0.5	0.9
Asthma	0.3	0.6	1.2	0.2	-1.1
Tense / ‘highly strung’	0.3	0.5	1.0	-0.3	1.0
Peak expiratory flow (PEF)	0.3	0.6	1.2	0.2	1.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	1.0	-0.3	1.0
Chronic bronchitis/emphysema (mother)	0.3	0.4	0.5	-0.5	0.7
Age at first live birth	0.3	0.6	1.0	-1.0	-0.4
Medication for pain relief, constipation, heartburn	0.3	0.6	0.7	-0.9	-0.6
Heart disease (mother)	0.3	0.3	0.4	-0.6	0.5
Suffer from ‘nerves’	0.3	0.5	0.5	-0.7	0.7
Age at last live birth	0.3	0.4	0.7	-0.8	-0.4
Family relationship satisfaction	0.3	0.3	0.6	-0.8	0.3
Medication: Aspirin	0.3	0.3	0.5	0.5	-0.7
Illnesses of father: Heart disease	0.3	0.4	0.5	-0.6	-0.7
Smoking status: Previous	0.3	0.4	0.7	0.9	-0.4
Loneliness, isolation	0.3	0.4	0.8	-0.3	0.9
Number of self-reported non-cancer illnesses	0.3	0.5	1.0	1.0	-0.2
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.6	-0.4	0.8
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.4	0.6	0.6
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.4	-0.6	-0.6
Age started oral contraceptive pill	0.3	0.4	0.9	0.9	-0.0
Worry (Nagel 2018)	0.2	0.5	1.0	-1.0	-0.2
Crohns Disease (2017)	0.2	0.4	0.8	0.9	-0.1
HbA1C	0.2	0.2	0.4	0.6	-0.1
Blood Red Count	0.2	2.1	2.9	-1.7	-1.1
Number of treatments/medications taken	0.2	0.4	0.7	0.8	-0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.4	0.4	-0.6
Townsend deprivation index at recruitment	0.2	0.3	0.4	0.5	0.7
Medication: Atenolol	0.2	0.3	0.4	-0.5	-0.6
Impedance of leg (left)	0.2	1.0	2.0	-1.4	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.4	-0.4	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	0.8	-0.4	-0.9
Heart attack	0.2	0.3	0.4	-0.6	0.4
Fluid intelligence score	0.2	0.4	0.8	0.0	-0.9
Illnesses of siblings	0.2	0.3	0.5	-0.7	-0.3
Time employed in main current job	0.2	0.2	0.4	-0.1	0.6
Happiness	0.2	0.2	0.4	-0.6	0.1
Illnesses of mother	0.2	0.3	0.3	-0.5	0.5
Impedance of arm (left)	0.2	0.7	0.8	-0.9	-0.9
Breastfed as a baby	0.2	0.3	0.4	-0.6	0.5
High blood pressure (siblings)	0.2	0.2	0.5	0.7	-0.1
Number of full brothers	0.2	0.3	0.6	-0.2	0.7
Migraine (self-reported)	0.2	0.3	0.4	-0.4	0.6
Leg pain on walking	0.2	0.2	0.3	0.4	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.5	-0.7	0.2
Mood swings	0.2	0.4	0.6	-0.8	-0.4
Asthma (self-reported)	0.2	0.3	0.6	0.0	-0.8
Medication: Aspirin	0.2	0.3	0.4	0.6	-0.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.3	-0.5	-0.5
Basal cell carcinoma (self-reported)	0.2	0.2	0.3	-0.2	-0.6
Impedance of whole body	0.2	1.2	2.1	-1.4	-0.5
Bipolar Disorder or Schizophrenia	0.1	0.3	0.4	0.4	0.6
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.3	0.5	0.3
Schizophrenia (2018)	0.1	0.2	0.4	0.7	-0.2
Schizophrenia (2014)	0.1	0.3	0.6	0.3	0.8
Heel T-Score	0.1	0.5	1.0	0.3	-1.0
Respiratory disease	0.1	0.2	0.3	-0.6	0.4
Lung FVC	0.1	0.4	0.7	0.8	0.3
Hair Pigment	0.1	1.6	2.3	-1.0	1.5
Average weekly spirits intake	0.1	0.1	0.2	0.0	-0.4
Relative age of first facial hair	0.1	0.2	0.4	-0.6	0.2
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.3	0.2	0.5
Eye problems/disorders: Diabetes related eye disease	0.1	0.2	0.2	-0.4	-0.4
Angina	0.1	0.2	0.2	-0.4	0.4
Vitamin and mineral supplements	0.1	0.1	0.1	0.4	0.2
Impedance of leg (right)	0.1	0.5	1.1	-1.0	0.0
Taking other prescription medications	0.1	0.2	0.3	0.3	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.4	0.2	-0.6
Pain all over the body in last month	0.1	0.1	0.2	0.2	0.4
Gout (self-reported)	0.1	0.2	0.3	-0.0	0.6
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.2	-0.2	0.5
Health satisfaction	0.1	0.1	0.2	-0.3	0.4
Angina (self-reported)	0.1	0.1	0.1	-0.3	0.3
Medication: Omeprazole	0.1	0.1	0.2	0.4	-0.2
Supplements: Vitamin C	0.1	0.2	0.2	-0.5	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.1	-0.1	0.4
Qualifications: nursing, teaching	0.1	0.2	0.2	-0.3	-0.5
Mineral and other dietary supplements	0.1	0.2	0.2	-0.4	-0.4
Osteoporosis (self-reported)	0.1	0.1	0.3	0.5	-0.1
Alcohol drinker status: Never	0.1	0.1	0.1	0.1	0.4
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.2	-0.5	0.3
Verbal and Numeric Reasoning (VNR)	0.0	0.1	0.1	0.1	0.3
Crohns Disease (2012)	0.0	0.1	0.1	-0.0	-0.3
Rheumatoid Arthritis	0.0	0.0	0.1	-0.0	-0.3
Triglycerides	0.0	0.0	0.0	0.1	-0.2
Systolic Blood Pressure	0.0	0.0	0.1	-0.3	0.0
Tanning	0.0	0.3	0.4	-0.5	-0.6
Qualifications: CSEs or equivalent	0.0	0.0	0.0	0.2	0.2
Supplements: Glucosamine	0.0	0.0	0.0	0.2	-0.2
Birth weight	0.0	0.0	0.0	0.0	-0.1
Worry too long after embarrassment	0.0	0.1	0.1	-0.3	-0.1
Number of children fathered	0.0	0.1	0.1	0.3	0.1
Commuting to job workplace: Car/motor vehicle	0.0	0.0	0.0	-0.1	-0.2
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.0	-0.2	0.2
Commuting to job workplace: Walk	0.0	0.0	0.0	0.2	0.0
Wears glasses or contact lenses	0.0	0.0	0.0	-0.1	-0.1
Irritability	0.0	0.1	0.1	-0.0	0.3

Hub : Genes

RASGEF1B

Models

Trait associations