Hub : Genes

RASGRF2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1280	0.0390	1.6e-05	0.045	0.047	0.043	0.055	0.036	2.9e-06	2.0e-06	5.6e-06	3.1e-07	2.8e-05
2	GTEx	Adipose Subcutaneous	0.1030	0.0440	8.9e-03	0.069	NA	0.041	NA	0.054	2.7e-06	NA	2.6e-04	NA	2.9e-05
3	GTEx	Colon Transverse	0.2270	0.0800	6.6e-03	-0.005	NA	0.000	NA	-0.005	6.5e-01	NA	3.3e-01	NA	6.4e-01
4	GTEx	Liver	0.2970	0.1060	3.8e-03	0.049	NA	0.036	NA	0.088	1.7e-02	NA	3.6e-02	NA	2.0e-03
5	GTEx	Thyroid	0.2630	0.0770	1.7e-04	0.033	NA	0.110	NA	0.091	1.4e-03	NA	9.7e-09	NA	1.9e-07
6	METSIM	Adipose	0.2436	0.0416	2.9e-15	0.161	0.126	0.149	0.164	0.160	2.0e-23	2.5e-18	1.3e-21	8.5e-24	3.6e-23
7	TCGA	Breast Invasive Carcinoma	0.0317	0.0149	4.8e-03	0.027	0.012	0.021	NA	0.024	2.9e-06	1.1e-03	2.5e-05	NA	8.6e-06
8	TCGA	Pheochromocytoma and Paraganglioma	0.2410	0.0850	1.7e-03	0.019	0.041	0.062	NA	0.051	5.8e-02	9.7e-03	1.9e-03	NA	4.4e-03
9	TCGA	Thyroid Carcinoma	0.1160	0.0380	6.2e-05	0.070	0.067	0.061	NA	0.057	2.4e-07	4.3e-07	1.4e-06	NA	2.9e-06

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.6	0.9	2.5	1.0	-0.3	-1.2	0.2	-1.6	-0.5	-0.4	1.5	-0.8
Bipolar Disorder or Schizophrenia	0.2	0.6	1.6	1.3	-0.6	-0.8	0.1	0.3	-1.0	0.8	0.2	0.8
Depressed Affect (Nagel 2018)	0.7	1.4	2.9	-1.5	-0.7	-0.8	-1.0	-0.1	-1.6	-1.7	-1.6	-0.8
Depression (Nagel 2018)	0.5	0.8	3.3	-0.3	-1.0	0.8	-0.8	0.7	-1.8	-0.5	-0.8	0.5
Intelligence (Savage-Jansen 2018)	0.5	1.5	3.6	-1.4	-1.9	0.7	-0.2	-0.9	-1.6	-1.2	-1.3	-0.9
Neuroticism (Nagel 2018)	1.3	3.1	10.0	-0.8	-0.2	-0.7	-2.0	-1.2	-0.9	-3.2	-2.5	-2.2
Schizophrenia (2018)	0.5	1.1	3.1	0.9	-0.5	-0.1	0.1	1.6	-0.9	1.3	-0.8	1.8
Schizophrenia vs Biploar Disorder	0.5	0.7	2.6	-0.8	-0.2	0.5	-0.2	1.6	-0.2	0.7	0.0	1.3
Worry (Nagel 2018)	1.7	3.6	11.2	1.0	-0.4	-1.0	-1.8	-1.6	-1.1	-3.4	-2.2	-2.6
Alzheimer’s Disease (in mother)	1.2	1.4	4.5	-2.1	-0.6	1.5	-1.4	0.9	0.6	-0.5	-1.4	-0.2
Alzheimer’s Disease (in father)	0.4	0.5	1.7	1.3	-0.2	0.0	-0.5	-0.8	-0.7	-0.8	0.3	0.2
Alzheimer’s Disease (including proxy)	0.5	0.8	2.4	-0.5	-0.2	0.7	-1.6	-0.7	0.3	-1.1	-1.1	-0.7
Crohns Disease (2017)	0.1	0.3	1.5	0.5	0.3	-1.2	-0.5	0.4	0.0	-0.7	-0.3	0.2
Irritable Bowel Disease (IBD)	0.3	0.7	2.4	-0.9	0.4	-0.4	-1.6	1.1	0.1	-0.9	0.3	-0.7
Ulcerative Colitis (UC)	0.7	1.2	3.2	-1.8	0.0	0.9	-1.6	1.1	-0.1	-0.9	0.3	-1.6
Major Depression (MDD)	0.5	0.6	1.9	-1.0	-0.5	0.3	1.0	1.4	-1.0	0.4	-0.0	0.3
Reaction Time	0.7	1.4	2.9	1.4	-0.6	-1.7	-0.8	-1.1	-0.5	-1.0	-1.2	-1.5
Verbal and Numeric Reasoning (VNR)	0.5	1.1	3.2	-0.8	-0.9	0.1	0.3	-1.5	-0.5	-1.6	0.3	-1.8
Breast Cancer	0.6	1.4	3.6	-0.5	1.5	1.9	0.2	-0.9	1.2	-1.4	-1.1	-1.1
Ovarian Cancer	0.3	0.4	1.0	0.8	0.6	1.0	0.3	0.3	-0.0	0.4	0.6	0.7
Prostate Cancer	0.6	0.9	2.5	0.4	1.1	-0.7	-1.6	1.2	1.0	0.5	0.3	0.8
Age at First Birth	0.4	0.5	1.5	1.2	-0.7	0.6	-0.3	-0.2	-0.4	0.2	1.2	-0.9
Bipolar Disorder (2011)	0.4	0.4	1.4	-0.7	0.7	-0.1	0.3	-1.2	0.3	0.1	-1.1	0.2
Body Mass Index (BMI) (2010)	0.3	0.5	1.7	1.3	-0.5	-1.3	0.1	0.0	-0.6	-0.4	0.3	-0.4
Coronary Artery Disease (CAD)	0.4	0.5	2.3	-0.8	-0.3	-0.7	0.3	-0.6	-0.7	-0.2	1.5	0.4
Crohns Disease (2012)	1.3	2.0	4.8	1.0	2.1	-2.2	0.2	1.4	2.0	0.6	0.3	1.3
Mean Putamen Volume	0.6	0.7	3.0	-0.9	-0.2	1.2	0.5	-0.2	-0.3	-0.4	-1.7	-0.6
Fasting Glucose	0.3	0.4	1.2	-1.1	0.0	0.8	-0.1	-0.2	-0.0	-0.7	0.6	-0.8
HbA1C	0.3	0.4	0.9	-0.2	0.9	-0.7	-0.2	-0.4	0.9	-0.5	-0.8	0.3
HDL Cholesterol	0.7	1.2	5.7	0.1	-0.2	-0.1	-2.4	0.2	-0.1	-2.2	-0.6	-0.1
LDL Cholesterol	0.2	0.3	0.9	-0.0	0.8	-1.0	-0.4	-0.7	0.1	-0.6	0.1	-0.4
Lupus	0.7	1.1	2.6	-0.4	-0.0	-0.9	-1.4	0.5	-0.5	-1.6	1.0	-1.6
Neuroticism (2016)	0.9	1.2	3.4	-1.1	-1.6	0.5	-1.8	0.3	-1.8	0.1	-0.5	-0.2
Primary Biliary Cirrhosis	0.4	0.6	2.1	-0.2	-0.0	-1.5	-1.2	0.2	0.2	-1.0	-0.1	-0.8
Rheumatoid Arthritis	0.8	1.2	4.7	-0.9	0.4	2.2	-1.4	1.4	0.2	-0.5	0.2	-0.5
Schizophrenia (2014)	0.7	1.6	5.2	0.4	-1.1	-1.1	-1.1	2.3	-0.9	1.2	-0.2	1.7
Triglycerides	0.5	0.9	1.8	-1.3	1.1	1.3	0.5	1.1	1.0	0.7	-0.7	0.2
Type 2 Diabetes (T2D) (2012)	1.9	2.2	7.5	-1.9	0.1	-1.4	-1.8	-1.1	0.8	-1.4	-0.2	-2.7
Ulcerative Colitis	0.7	1.0	4.0	-2.0	0.5	0.0	-1.1	1.1	1.0	-0.2	0.5	-1.0
Blood Eosinophil Count	0.1	0.6	2.6	0.2	0.1	1.4	0.3	-0.9	0.2	0.1	-1.6	-0.5
Blood Platelet Count	0.1	0.6	2.2	-0.8	0.6	-0.2	-0.1	-0.8	0.9	1.5	1.0	-0.3
Blood Red Count	0.1	0.9	4.4	-0.2	-0.9	-1.1	-0.5	2.1	-0.2	0.7	-0.8	0.3
Blood White Count	0.1	0.7	1.3	0.1	-1.1	-1.2	0.4	-0.4	-1.1	-0.9	-1.0	-0.7
Heel T-Score	5.4	42.9	174.2	4.3	-1.3	-1.4	5.7	7.3	-0.5	13.2	4.5	9.1
BMI	0.5	2.9	11.2	1.4	-2.3	-3.4	-0.2	-1.0	-2.4	-0.7	0.6	0.1
Height	0.3	6.0	25.5	-0.8	-0.4	-0.3	0.2	4.2	-0.3	2.6	5.1	1.7
Waist Hip Ratio (WHR)	0.4	1.8	3.3	-1.8	0.7	1.5	-0.5	1.6	1.2	1.5	1.3	1.3
Systolic Blood Pressure	0.3	1.6	4.8	0.3	-2.2	0.5	-0.3	-0.6	-2.0	-1.0	0.5	-1.8
Smoking Status	1.4	3.4	7.3	1.5	1.1	-1.9	1.4	-1.2	1.1	2.7	-2.1	2.7
Allergy or Eczema	0.2	0.5	2.2	0.0	-0.1	0.1	-0.5	-1.0	1.5	-0.1	-0.4	-0.8
Cardiovascular Disease	0.3	1.0	3.9	-0.3	-0.9	-2.0	-1.3	-0.9	-0.7	0.0	-0.8	-0.3
Hypothyroidism (self reported)	0.5	1.2	2.4	0.8	-1.6	1.4	-1.4	-0.4	-1.6	-1.0	-0.6	-0.7
Respiratory disease	0.1	0.2	0.6	0.6	-0.2	-0.3	-0.8	0.2	0.2	0.3	-0.4	0.6
Type 2 Diabetes (T2D) (2018)	0.6	1.1	2.9	-0.8	0.3	-0.4	-1.5	-0.8	0.1	-1.7	-1.4	-1.1
Lung FEV1/FVC ratio	0.2	0.9	4.6	0.2	-1.0	-1.4	0.1	-0.3	-0.7	0.1	2.1	-0.2
Lung FVC	1.2	6.3	14.4	-1.9	3.1	1.6	-2.2	-2.9	2.3	-3.8	-1.9	-2.2
Neuroticism	0.9	2.1	7.9	0.7	-1.9	-1.1	-1.2	-0.2	-2.8	-1.6	-1.0	-0.6
Chronotype (morning person)	0.7	1.7	3.5	-1.5	-1.8	1.2	0.4	-0.6	-1.9	-1.7	0.6	-1.1
Hair Pigment	0.1	2.7	7.1	-0.4	2.6	-2.1	-2.3	0.0	2.7	0.1	0.5	-0.5
Tanning	0.1	1.7	3.7	1.9	0.8	0.2	0.4	1.3	1.8	1.9	-1.3	1.0
Hand grip strength (left)	0.5	1.3	4.8	1.3	1.7	-0.6	-0.6	-0.8	2.2	-0.1	0.5	-1.1
Number of treatments/medications taken	0.8	1.4	4.0	0.5	-0.8	-1.7	-1.2	-2.0	-1.1	-1.0	-0.9	-0.8
Average weekly spirits intake	0.4	0.5	2.2	0.2	0.8	0.1	0.1	0.2	0.3	0.2	-1.2	1.5
Sensitivity / hurt feelings	0.7	1.3	3.2	1.1	-1.8	-0.7	-1.2	-0.8	-1.1	-1.4	-0.5	-1.1
Frequency of depressed mood in last 2 weeks	1.3	1.9	5.1	0.5	-1.6	0.3	-1.6	-0.9	-2.3	-1.6	-1.5	-0.7
Hearing difficulty/problems: Yes	0.7	1.1	2.6	-1.3	-1.5	0.6	-0.3	-0.9	-0.8	-1.1	-1.6	-0.6
Relative age of first facial hair	0.8	1.6	6.7	2.0	1.1	-2.6	-0.1	-0.7	0.8	-0.3	-1.0	0.3
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.8	-0.3	-0.5	-1.4	-0.8	-1.1	-0.2	-0.2	-0.2	0.9
Ever used hormone-replacement therapy (HRT)	0.8	1.0	3.0	0.4	0.6	-1.7	1.6	-0.0	0.1	1.1	-0.5	1.1
Ever had hysterectomy (womb removed)	2.3	2.7	7.2	-0.4	-2.7	-1.4	-1.7	-0.5	-2.2	-1.9	-1.3	-1.1
Systolic blood pressure, automated reading	0.2	0.5	1.2	0.8	-1.1	-1.1	0.5	-0.7	-0.8	0.1	0.0	-0.5
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.4	-0.9	0.1	1.2	0.2	0.5	0.3	0.7	0.9	-0.3
Angina	1.8	2.4	8.6	-1.1	-2.3	1.6	0.9	-1.2	-2.9	-1.0	0.6	-0.5
Medication for hormone replacement therapy	0.9	1.0	2.4	1.1	0.2	-0.1	1.4	-1.6	-0.9	-1.3	0.3	-0.7
Vitamin and mineral supplements	0.5	0.7	4.5	-2.1	0.1	0.9	0.0	0.8	0.4	-0.4	0.2	0.6
Supplements: Zinc	1.1	1.2	6.0	2.4	0.5	-1.5	-0.5	-1.0	0.3	-0.3	0.6	-0.7
Medication: Co-codamol	0.3	0.4	1.4	-0.4	-0.1	0.2	-0.2	-1.2	-0.3	-0.9	0.4	-0.7
Medication: Metformin	2.3	3.2	8.0	-1.6	-0.7	-0.1	-2.8	-1.4	-0.2	-2.8	-1.1	-2.6
Diabetes (father)	0.2	0.3	1.1	0.7	-1.1	-0.6	0.2	0.1	-0.3	-0.4	0.3	0.1
Diabetes (mother)	0.8	1.0	2.2	-1.1	-0.8	0.6	0.4	-1.3	-1.2	-0.8	0.7	-1.5
Severe depression (siblings)	0.4	0.5	1.4	-0.1	0.7	-0.6	0.0	-0.7	0.5	-1.2	-1.1	-0.4
Pack years adult smoking proportion	0.8	1.2	2.6	-0.4	1.3	-1.6	0.9	0.8	1.2	1.6	-0.6	1.1
Impedance of leg (right)	0.3	1.3	4.1	-0.6	1.0	2.0	-0.6	-0.3	1.4	-0.7	-1.3	-1.4
Leg fat-free mass (left)	0.4	1.9	6.4	-0.1	-1.5	-1.6	-0.3	1.0	-1.9	0.2	2.5	0.9
Trunk fat percentage	0.4	1.6	6.2	-0.8	-1.3	-2.5	-0.3	-1.4	-1.7	-0.3	-0.7	-0.2
Hand grip strength (right)	0.3	0.8	4.8	0.3	1.3	-0.1	-0.4	-0.3	2.2	0.0	0.5	-0.3
Townsend deprivation index at recruitment	0.7	1.0	2.2	1.4	-1.4	0.5	0.8	-0.7	-1.5	-0.2	-0.5	0.9
Current tobacco smoking	1.6	2.5	7.7	2.8	1.3	-1.6	1.8	-0.6	0.9	1.6	-1.2	1.6
Average weekly fortified wine intake	0.5	0.6	1.1	0.4	0.6	-1.0	-0.1	-0.9	1.0	1.1	-1.0	-0.2
Maternal smoking around birth	4.2	6.1	16.6	1.6	-1.0	-1.1	3.2	2.2	-1.2	4.0	0.8	4.1
Fed-up feelings	0.5	0.9	3.1	-0.6	-1.1	0.0	-0.2	-0.0	-1.6	-1.8	-0.8	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.2	-1.1	-1.2	0.9	0.2	0.4	-1.5	-0.3	-0.7	0.9
Relative age voice broke	1.1	1.6	4.1	0.6	1.3	-2.0	-0.7	-1.9	1.0	-1.0	-0.7	-1.2
Taking other prescription medications	1.0	1.6	3.7	-0.4	-0.8	0.5	-1.5	-1.9	-0.9	-1.9	-1.2	-1.3
Age when periods started (menarche)	0.4	1.0	2.3	-0.2	0.8	0.9	1.0	0.6	0.4	1.5	-1.0	1.5
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.7	-0.5	-1.7	-0.2	1.6	0.7	-1.9	0.6	-0.0	1.6
Heel bone mineral density (BMD) T-score, automated (left)	4.9	11.1	48.9	1.6	0.5	-0.6	3.1	3.9	0.4	7.0	1.1	4.6
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.4	-0.4	0.9	0.7	-0.1	-0.7	1.1	-0.6	0.0	-1.2
Qualifications: CSEs or equivalent	0.7	0.9	2.7	0.2	0.8	0.8	-1.2	-0.0	0.7	-1.6	-0.3	-1.4
Serious illness, injury or assault to yourself	0.9	1.1	4.5	-0.5	0.7	2.1	1.6	-1.3	-0.5	0.1	0.2	0.4
High blood pressure	0.4	1.0	3.7	0.8	-1.8	-1.9	-0.4	-0.2	-1.1	0.3	0.2	0.2
Hayfever, allergic rhinitis or eczema	0.3	0.6	2.4	0.5	0.3	0.9	-0.1	-1.1	1.6	-0.6	0.0	-0.9
Multivitamins +/- minerals	0.8	1.0	3.6	1.9	-0.3	0.3	1.2	-0.5	-1.1	1.3	-0.1	0.7
Stomach or abdominal pain in last month	1.4	1.8	5.8	0.4	-1.6	-0.5	1.2	0.7	-0.4	1.8	1.5	2.4
Supplements: Glucosamine	1.0	1.3	5.5	0.1	0.9	-2.3	-0.3	0.2	1.2	1.8	0.1	0.9
Diverticular disease/diverticulitis (self-reported)	0.9	1.0	3.7	-0.2	-0.7	0.1	1.9	0.5	-1.1	1.5	-0.0	1.2
Medication: Atenolol	1.1	1.4	4.5	0.3	-1.6	-0.4	-1.7	-0.6	-2.1	-1.3	-0.7	-0.3
Medication: Levothyroxine sodium	1.3	2.1	7.7	2.0	-2.5	0.4	-0.5	-0.0	-2.8	-0.5	-0.7	-0.2
Sitting height	0.2	1.4	3.4	-1.4	0.7	-0.1	1.6	1.1	0.5	1.9	1.5	0.6
Chronic bronchitis/emphysema (father)	1.3	1.5	5.9	-0.4	0.0	-1.0	0.7	-2.4	-0.7	-1.3	-1.4	-1.4
High blood pressure (mother)	0.9	1.3	4.8	0.0	-2.2	-0.3	0.3	-1.5	-1.8	-0.7	-0.6	-0.8
Body mass index (BMI)	0.4	1.9	5.3	-0.6	-2.1	-2.1	0.1	-1.2	-2.3	-0.4	0.3	0.2
Impedance of leg (left)	0.4	1.9	5.2	-0.8	1.2	2.3	-0.8	-0.4	1.6	-0.5	-1.9	-1.5
Leg predicted mass (left)	0.4	1.9	6.5	-0.0	-1.5	-1.7	-0.3	1.0	-1.9	0.2	2.5	0.8
Trunk fat mass	0.4	1.6	5.5	-0.9	-1.8	-2.4	-0.4	-0.6	-2.1	-0.1	0.1	0.1
Waist circumference	0.5	1.7	4.0	-1.8	-1.7	-2.0	-1.1	-0.6	-1.6	-0.6	0.7	-0.1
Number of incorrect matches in round	1.1	1.8	6.3	-0.1	1.6	0.1	-2.5	-0.4	1.5	-1.1	-1.4	-1.1
Past tobacco smoking	0.4	0.8	1.9	-0.5	0.1	1.1	-0.5	1.4	-0.2	-1.0	0.9	-1.1
Alcohol usually taken with meals	0.8	1.3	3.2	0.9	-0.9	-0.5	1.7	0.7	-0.0	1.8	1.8	-0.7
Nervous feelings	3.0	5.6	15.4	-0.2	-1.5	-0.4	-2.2	-2.0	-2.1	-3.9	-2.9	-3.3
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.8	9.2	-0.5	-3.0	-0.2	-1.9	-0.0	-2.9	-1.2	-1.4	0.1
Hearing difficulty/problems with background noise	0.3	0.5	2.4	-1.1	-1.5	0.3	-0.3	-0.4	-0.8	-0.2	-0.1	0.4
Hair/balding pattern: Pattern 2	0.4	0.5	1.5	-0.5	-0.4	-0.8	-0.5	-0.1	-0.3	-0.2	-1.1	-1.2
Had menopause	0.6	0.8	2.3	-0.1	1.5	-1.0	0.1	-0.4	1.3	0.7	-0.8	-0.7
Had other major operations	0.2	0.3	0.8	0.7	0.0	0.5	-0.3	-0.2	0.6	0.9	0.6	0.3
Forced vital capacity (FVC)	0.3	1.3	4.8	-1.3	1.5	2.2	-0.3	0.8	1.2	-0.3	0.5	0.5
Heel bone mineral density (BMD) T-score, automated (right)	5.5	12.6	50.3	2.8	-1.0	-1.1	3.0	4.1	-0.7	7.1	1.8	4.9
Ever unenthusiastic/disinterested for a whole week	1.7	2.1	8.4	-2.9	0.7	2.0	-1.5	-0.1	0.5	-1.2	-0.5	-1.4
Qualifications: None of the above	1.0	2.2	5.3	-1.9	-0.8	0.3	-1.0	-1.3	-0.5	-2.3	-1.8	-1.8
Financial difficulties in last 2 years	1.1	1.5	4.6	0.5	-1.4	-0.3	0.3	0.6	-1.2	2.1	0.3	2.1
Mouth/teeth dental problems	0.8	1.2	5.0	2.2	-0.4	0.1	-0.9	0.2	0.5	1.0	1.9	0.1
Heart attack	0.4	0.5	1.3	-0.8	-0.3	0.6	1.1	0.2	-0.5	-0.1	1.1	0.5
Allergy	0.3	0.7	2.1	-0.3	-0.6	-1.4	0.7	1.2	-1.2	0.5	-0.1	0.6
Pain all over the body in last month	0.9	0.9	3.8	-0.9	-1.4	-1.0	0.3	0.2	-1.9	0.3	-0.6	-0.7
Diabetes (self-reported)	1.2	1.8	4.4	-1.5	1.1	-0.7	-2.1	-1.3	1.0	-1.6	-0.4	-1.6
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	5.8	-1.1	-0.3	1.2	-1.1	-0.9	-0.3	-1.0	0.2	-2.4
Medication: Ramipril	0.7	0.9	2.1	-0.4	-1.4	-0.4	-0.9	1.2	-1.1	0.0	-0.9	1.2
Medication: Simvastatin	1.3	1.9	5.5	-0.9	0.5	-0.0	-1.6	-1.8	-0.0	-2.4	-1.0	-1.8
Fluid intelligence score	0.2	0.5	1.4	0.0	-0.1	-1.2	0.5	0.5	0.2	-1.2	0.9	-0.3
Illnesses of siblings	0.5	0.7	2.1	-0.5	1.2	-0.8	-0.6	1.1	0.6	1.5	0.1	-0.2
Neuroticism score	1.7	3.5	13.1	0.5	-2.7	-0.1	-0.5	-1.3	-3.6	-2.4	-1.5	-0.9
Weight	0.4	2.1	6.1	-1.0	-2.3	-2.0	0.0	0.3	-2.5	0.1	1.6	0.4
Impedance of arm (right)	0.2	1.0	5.4	0.5	2.3	0.7	-0.3	-0.2	1.5	-0.1	-0.8	-0.2
Arm fat percentage (right)	0.4	1.7	6.1	-0.4	-1.5	-2.5	-0.2	-1.5	-2.0	-0.3	-0.1	0.2
Trunk fat-free mass	0.4	2.4	7.9	-0.5	-2.0	-0.3	-0.1	2.2	-2.0	0.5	2.8	0.9
Hip circumference	0.6	2.6	6.0	-1.1	-2.3	-2.3	-0.5	-1.4	-2.5	-1.4	1.0	-0.9
Time employed in main current job	0.2	0.2	1.0	-0.1	-1.0	-0.2	0.2	0.4	-0.5	-0.6	0.1	0.5
Alcohol intake versus 10 years previously	1.1	1.6	3.8	-1.0	-2.0	1.8	-1.3	1.2	-1.4	-1.0	0.5	0.0
Father’s age at death	0.9	1.2	2.4	-1.5	1.4	0.7	0.7	0.4	1.4	0.0	1.0	-1.6
Worrier / anxious feelings	1.8	3.4	8.3	0.3	-2.2	0.3	-0.6	-2.6	-2.9	-2.3	-1.7	-1.5
Frequency of tiredness / lethargy in last 2 weeks	1.2	1.9	6.0	-2.4	-1.6	1.9	-1.0	0.5	-1.3	-0.7	-0.6	1.2
Falls in the last year	0.9	1.2	2.7	-1.0	-1.3	0.4	1.6	-0.5	-1.6	0.7	1.0	1.0
Hair/balding pattern: Pattern 3	0.4	0.7	2.6	0.3	0.2	0.7	1.2	0.8	-0.0	0.8	0.3	1.6
Number of live births	0.8	1.1	3.2	-1.3	-0.7	0.6	-1.8	-0.5	-0.9	-0.9	-1.0	-1.3
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.5	-0.9	0.5	1.2	-0.9	0.8	0.5	-0.5	0.9	0.3
Pulse rate	1.0	1.6	4.4	-0.9	-1.2	2.1	-0.6	-1.7	-0.7	-1.2	1.1	-1.2
Happiness	0.8	1.0	6.2	0.4	-0.5	2.5	0.8	1.1	-0.8	0.0	0.2	0.1
Noisy workplace	0.6	0.8	2.2	0.4	-0.6	0.4	0.0	-1.5	-0.7	-1.2	-1.3	-0.6
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.6	1.3	1.2	-0.2	0.4	0.0	0.8	1.1	0.0	0.0
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	6.3	2.5	0.5	-1.4	1.8	-0.4	0.6	0.8	-0.4	0.5
Mouth/teeth dental problems: Dentures	0.3	0.6	1.8	-1.3	-0.6	0.4	-0.3	-0.8	-0.8	0.2	-1.2	0.1
Asthma	0.3	0.5	1.1	-0.2	0.9	1.0	-0.9	-0.7	1.0	-0.3	0.3	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	3.7	0.5	-0.7	0.1	1.2	0.1	-0.6	1.5	1.0	1.9
Medication: Cholesterol lowering	0.4	0.6	1.3	-0.8	-0.6	-0.7	-0.0	-1.2	-0.7	-0.5	1.1	-0.5
Depression (self-reported)	1.7	2.1	4.9	-0.5	-1.7	1.0	-1.6	-1.1	-2.2	-1.8	0.3	-1.6
Medication: Lansoprazole	0.3	0.3	1.1	-0.5	-0.3	-0.8	-1.0	-0.8	-0.1	-0.7	-0.2	0.2
Prospective memory result	0.7	0.8	1.9	-0.5	0.7	-0.7	-1.1	-1.2	0.7	-1.4	0.2	-1.2
Lung cancer (father)	0.5	0.6	1.7	-1.3	-1.2	-0.3	-0.5	-0.7	-0.7	-0.8	-0.8	-0.2
Illnesses of mother	0.9	1.1	3.7	0.9	1.9	1.5	0.1	0.5	1.7	0.4	-0.2	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	4.2	-0.9	0.8	2.0	-2.0	0.4	0.6	-1.1	0.8	-0.1
Pulse wave Arterial Stiffness index	1.1	1.3	3.6	-1.3	1.7	1.3	-0.9	-1.0	1.9	-0.4	0.2	0.3
Impedance of arm (left)	0.3	1.2	5.5	0.5	2.3	0.4	0.2	-0.1	1.6	0.4	-1.4	-0.3
Arm fat mass (right)	0.5	1.9	6.5	-0.8	-2.0	-2.5	-0.3	-0.7	-2.2	-0.2	0.7	0.3
Trunk predicted mass	0.4	2.4	7.7	-0.4	-2.0	-0.3	-0.1	2.2	-1.9	0.5	2.8	0.8
Standing height	0.2	2.1	9.3	-0.7	-0.7	-0.2	-0.5	3.0	-0.7	1.1	2.5	0.7
Length of working week for main job	0.8	0.9	2.2	1.0	-1.5	-1.1	-1.1	-0.4	-1.0	0.4	0.2	-1.0
Exposure to tobacco smoke at home	0.7	0.7	3.1	0.1	0.6	0.3	0.4	0.4	0.6	0.0	-1.8	1.5
Breastfed as a baby	1.1	1.4	4.1	-1.2	0.4	0.9	0.2	1.6	1.0	1.6	2.0	0.5
Tense / ‘highly strung’	0.6	1.0	4.3	0.0	-0.1	-0.6	-1.3	0.1	-1.4	0.3	-2.1	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	4.0	-0.4	-1.8	0.5	-1.0	-0.7	-2.0	-1.6	-0.6	-0.1
Hair/balding pattern: Pattern 4	0.2	0.5	1.1	-0.2	0.3	-0.1	-0.6	-1.1	0.1	-0.4	-1.1	-1.1
Birth weight of first child	0.4	0.7	2.5	0.8	-1.1	0.1	0.4	-0.3	-1.6	-0.8	-0.3	-0.9
Peak expiratory flow (PEF)	0.4	0.8	4.2	0.2	0.3	-0.8	0.8	0.7	0.8	0.7	2.1	0.2
Pulse wave reflection index	1.8	2.3	6.7	-0.4	2.6	0.9	-1.2	-1.5	2.1	-1.1	-1.8	-0.5
Ever highly irritable/argumentative for 2 days	0.8	0.9	3.5	0.2	-1.9	-0.3	0.9	0.5	-1.7	0.2	-0.7	0.5
Loud music exposure frequency	1.7	1.9	5.7	-0.0	-2.1	-1.2	1.6	-0.1	-2.4	0.8	1.3	0.3
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.4	1.2	0.2	-0.3	0.1	0.7	0.5	1.0	0.5	0.6
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	3.0	-0.9	-0.1	-0.1	0.6	0.8	-0.6	-1.7	-0.3	-0.7
Blood clot in the leg (DVT)	0.4	0.5	1.8	-1.3	-0.4	0.4	-0.7	-0.1	-0.9	-1.1	0.0	0.1
Medication: Paracetamol	0.9	1.5	4.3	-0.5	-1.6	1.4	0.7	1.2	-2.1	0.1	1.5	0.3
Headache pain in last month	1.5	2.6	6.1	-0.7	-1.2	1.6	1.1	2.1	-1.4	1.6	1.6	2.5
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.6	1.0	0.3	0.8	1.3	0.2	0.6	1.2	-0.6	0.7
Glaucoma (self-reported)	0.8	1.0	2.9	0.7	-1.0	-0.1	0.5	-1.7	-0.3	-1.3	0.8	-1.4
Gout (self-reported)	0.4	0.6	1.3	-0.3	-0.9	0.7	-0.7	0.1	-1.1	-0.6	-1.0	-0.9
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	6.5	1.4	-2.5	1.0	-1.0	-0.2	-2.5	-0.2	-0.2	0.1
Medication: Amlodipine	0.3	0.4	1.4	-0.7	-0.3	-0.7	-0.3	0.8	-0.1	0.8	-0.2	1.2
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.7	0.4	-0.4	0.3	-0.1	0.3	-1.3	0.2	-1.1	0.8
Birth weight	0.4	0.8	4.0	0.4	-0.9	0.6	-0.4	0.6	-0.8	-0.8	2.0	0.1
Chronic bronchitis/emphysema (mother)	2.7	3.2	11.7	1.3	-0.8	-1.5	1.0	1.6	-0.4	3.4	-0.8	2.9
High blood pressure (siblings)	0.3	0.5	1.6	0.9	-0.5	-0.3	0.1	-1.0	0.0	-1.3	-0.6	0.1
Forced vital capacity (FVC), Best measure	0.5	1.8	8.8	-1.3	1.4	3.0	-1.4	0.7	1.0	-0.5	0.3	0.3
Body fat percentage	0.4	1.7	5.3	-1.1	-1.6	-2.3	-0.4	-1.5	-1.8	-0.4	-0.6	-0.3
Leg fat percentage (right)	0.5	1.8	4.6	-1.5	-2.1	-1.4	-0.6	-1.7	-1.8	-0.8	-0.3	-0.5
Arm fat-free mass (right)	0.5	2.5	6.7	-0.5	-2.4	-1.1	-0.1	1.9	-2.1	0.5	2.6	0.5
Exposure to tobacco smoke outside home	0.5	0.7	2.0	0.2	0.3	0.8	0.0	-1.4	1.2	-0.4	-1.1	-0.5
Comparative body size at age 10	0.1	0.3	1.2	0.3	0.0	-1.1	0.7	0.7	-0.6	0.3	0.4	0.2
Number of full brothers	0.5	0.6	3.4	0.0	0.3	1.9	1.1	-0.5	-0.4	-0.5	0.7	0.1
Worry too long after embarrassment	2.2	3.7	9.0	-0.6	-1.6	0.3	-3.0	-1.9	-1.6	-2.7	-2.2	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	1.0	4.0	0.2	-1.5	-0.0	-0.5	0.5	-2.0	-0.5	-0.5	1.1
Wheeze or whistling in the chest in last year	0.6	1.2	3.2	-1.3	-1.8	-0.1	1.1	-1.3	-1.3	0.1	-0.8	-0.4
Number of children fathered	1.5	1.7	7.0	-0.9	1.1	-0.3	0.4	2.0	1.3	0.3	0.2	2.6
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.9	9.1	0.7	-0.3	-1.4	-0.8	-3.0	-0.1	-1.3	-1.4	-1.0
Age at first live birth	0.8	1.4	5.3	1.2	2.3	-0.3	-0.2	-0.4	2.3	0.7	-0.1	-0.3
Pulse wave peak to peak time	1.1	1.3	3.8	1.1	-1.7	-1.1	0.8	1.3	-2.0	0.5	0.1	-0.2
Health satisfaction	0.9	1.2	2.9	-1.2	1.3	1.7	-0.6	-0.7	1.4	-1.0	0.7	-0.4
Shortness of breath walking on level ground	0.9	1.0	4.5	-0.1	-0.4	-0.2	0.4	-1.4	0.1	-1.4	-2.1	-0.7
Qualifications: College or University degree	0.5	1.6	7.9	-0.1	0.7	1.5	-1.0	1.2	0.8	0.7	2.8	-0.7
Eye problems/disorders: None of the above	1.1	1.3	4.6	-2.1	1.8	0.2	-0.8	0.0	1.3	-0.2	-1.1	-0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.3	1.3	-0.1	0.0	-1.2	0.5	0.4	-0.3	-0.3	-0.7	0.4
Emphysema/chronic bronchitis	1.4	1.6	4.3	0.9	-1.7	1.9	-0.3	0.5	-2.1	-0.5	0.9	1.1
Medication for pain relief, constipation, heartburn	0.4	0.7	1.6	-0.4	0.7	0.8	-1.1	-0.6	1.1	0.1	-1.3	-0.9
Neck or shoulder pain in last month	0.3	0.5	2.7	-1.6	-0.6	0.5	-0.4	-0.8	0.2	-0.2	-0.1	-0.1
Medication: Blood pressure	0.5	0.8	3.4	-0.0	-1.5	-0.9	-0.7	0.2	-1.9	-0.5	0.4	-0.3
Angina (self-reported)	1.9	2.5	8.8	-1.1	-2.4	1.6	0.8	-1.1	-3.0	-0.9	0.8	-0.5
Migraine (self-reported)	0.7	0.9	2.8	-0.3	1.0	-1.1	0.5	1.7	-0.2	1.1	0.0	1.3
Medication: Ibuprofen	0.3	0.4	2.5	0.2	-0.4	-0.1	0.3	0.1	-0.3	0.7	0.2	1.6
Medication: Allopurinol	0.3	0.4	0.8	0.7	-0.6	0.8	-0.2	-0.3	-0.9	-0.8	-0.0	-0.6
Medication: Omeprazole	0.6	0.7	2.0	-0.0	0.6	-1.1	1.0	-1.4	0.4	-0.5	0.2	-1.1
Medication: Seretide 50 evohaler	1.0	1.1	4.0	2.0	-0.4	-0.3	0.5	-1.9	-0.4	-1.0	-0.7	-0.6
Mean time to correctly identify matches	1.0	1.8	4.4	0.9	-0.8	-2.0	-0.6	-1.4	-0.7	-1.0	-2.1	-1.6
Heart disease (mother)	0.8	1.0	4.0	-0.9	-1.5	-0.4	0.4	-2.0	-1.0	0.1	0.9	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.0	0.6	-1.0	0.5	1.0	1.1	-0.7	1.4	-0.2	0.9
Whole body fat mass	0.4	1.8	6.7	-1.1	-1.9	-2.6	-0.3	-0.6	-2.0	-0.2	0.3	0.1
Leg fat mass (right)	0.4	1.5	4.2	-1.4	-2.0	-1.6	-0.8	-0.5	-1.9	-0.6	0.5	0.0
Arm predicted mass (right)	0.5	2.4	6.3	-0.5	-2.5	-1.0	-0.1	1.8	-2.2	0.5	2.3	0.4
Pulse rate, automated reading	0.4	1.3	5.6	-1.4	-1.1	2.4	-0.6	0.2	-0.9	-0.5	1.1	-0.1
Alcohol intake frequency.	1.7	3.9	10.6	-3.2	-1.2	2.2	-2.8	0.9	-1.6	-2.4	-0.8	-0.8
Comparative height size at age 10	0.4	2.4	7.0	-2.0	0.2	-1.0	0.2	2.5	0.6	1.7	2.6	0.0
Number of full sisters	0.3	0.3	0.9	0.9	-0.2	0.2	0.6	0.5	0.7	0.5	0.6	-0.2
Suffer from ‘nerves’	2.1	3.3	9.9	-0.1	-2.1	0.7	-1.7	-1.7	-1.9	-3.1	-0.7	-2.2
Overall health rating	0.4	0.9	5.4	-2.3	-0.7	0.9	-0.6	-0.6	-0.5	0.2	-0.1	0.6
Chest pain or discomfort	2.1	3.1	9.1	-3.0	-1.0	2.9	-1.5	-1.3	-0.6	-1.6	-0.4	-1.6
Had major operations	0.9	1.1	3.0	1.4	0.7	-0.9	-1.3	0.7	0.1	0.3	1.7	1.0
Age at last live birth	0.4	0.6	1.8	0.8	0.2	0.9	0.1	-1.3	0.2	0.3	0.1	-1.3
Family relationship satisfaction	0.8	1.0	6.2	0.3	0.1	2.5	0.3	1.1	-0.2	-0.4	0.9	0.2
Leg pain on walking	1.1	1.4	4.7	-1.3	-0.6	-0.3	-0.3	-2.2	-0.5	-2.0	-0.3	-1.1
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	4.7	1.6	-1.6	-1.2	2.2	-0.4	-1.6	1.5	0.2	0.6
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.4	0.7	0.0	0.2	-0.6	1.2	-0.2	1.2	0.3	1.6
Illness, injury, bereavement, stress in last 2 years	1.6	2.0	6.5	-1.3	0.6	0.9	-2.5	0.1	1.1	-1.9	-0.2	-1.8
Medication: Aspirin	0.9	1.1	6.4	0.1	-0.7	-2.5	-0.6	-0.5	-1.0	-1.1	-0.7	-0.1
Supplements: Vitamin C	0.8	0.9	4.7	0.4	-0.1	-0.7	-0.3	-0.8	0.5	-0.3	-1.3	-2.2
Knee pain experienced in last month	0.2	0.3	1.0	-0.5	-0.7	0.7	-0.4	0.3	-0.4	-0.4	-0.2	1.0
Hypertension (Self-reported)	0.4	1.0	4.0	0.3	-1.7	-2.0	-0.5	-0.7	-1.1	0.3	0.3	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	1.4	1.2	-0.1	-0.7	0.0	-0.3	-0.4	-0.5	0.1	0.1
Illnesses of father: Heart disease	0.3	0.4	1.4	-0.5	-0.7	0.5	0.1	0.7	-0.4	-0.4	1.2	-0.0
Illnesses of siblings: Diabetes	1.7	2.1	4.8	-2.2	-1.7	2.0	0.6	-0.9	-1.3	-1.6	0.7	-0.9
Smoking status: Previous	0.3	0.4	1.7	-0.1	-0.4	-1.3	0.2	-0.8	0.1	0.8	-0.4	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	2.4	-0.0	-1.5	0.9	0.1	1.0	-1.2	0.4	1.1	0.8
Whole body fat-free mass	0.4	2.3	7.7	-0.4	-1.9	-1.0	-0.1	1.9	-2.0	0.5	2.8	0.9
Leg fat-free mass (right)	0.3	1.6	5.2	-0.2	-1.4	-1.6	-0.2	1.0	-1.7	0.3	2.3	0.8
Arm fat percentage (left)	0.4	1.6	6.5	-0.2	-1.5	-2.6	0.0	-1.4	-1.9	-0.2	-0.3	0.2
Average weekly red wine intake	1.6	2.3	10.4	-0.5	0.5	-0.1	3.2	0.2	0.9	2.1	2.0	0.9
Handedness (chirality/laterality): Left-handed	0.4	0.4	1.3	0.4	1.1	0.1	0.8	0.5	1.1	0.1	0.2	0.7
Mood swings	1.4	2.4	7.7	-0.9	-2.2	0.3	-1.4	-1.2	-2.8	-1.5	-1.3	-0.9
Loneliness, isolation	0.9	1.3	2.8	0.1	-1.4	-0.7	-1.3	-0.7	-1.5	-1.7	-1.2	-1.0
Long-standing illness, disability or infirmity	1.1	1.7	5.1	0.4	-1.8	0.1	-0.6	0.7	-1.8	0.7	1.3	2.3
Ever had bowel cancer screening	1.9	2.2	4.9	0.5	-0.5	-1.8	1.5	2.2	-1.3	1.5	0.1	2.1
Diabetes diagnosed by doctor	1.3	2.1	5.1	-2.0	0.4	0.2	-2.3	-1.4	0.3	-1.9	-0.2	-2.1
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	2.1	0.2	-0.0	-0.1	1.1	-0.2	-0.8	0.9	1.4	0.1
Friendships satisfaction	1.0	1.3	6.3	0.6	1.1	2.5	0.3	1.1	0.6	0.3	0.1	1.3
Qualifications: nursing, teaching	1.0	1.5	5.5	1.0	-0.1	0.5	-0.8	1.5	0.5	2.4	-0.6	1.7
Commuting to job workplace: Walk	0.8	0.9	2.5	0.4	-0.4	-0.6	0.5	-1.5	-0.6	-1.6	-0.8	-1.1
Eye problems/disorders: Cataract	0.6	0.7	1.7	1.1	-1.2	-1.3	0.1	-0.7	-0.7	0.3	0.6	0.5
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	1.8	-0.5	-1.3	0.8	1.2	0.3	-1.2	-0.5	0.6	-0.5
Medication for cholesterol	1.2	1.9	5.7	-0.2	0.5	0.8	0.1	2.4	1.1	1.9	1.8	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.8	0.4	0.0	-0.2	-0.7	0.3	0.2	-0.3	1.4	1.2
Back pain experienced in last month	0.6	0.9	2.8	0.9	-1.2	-1.7	0.5	-0.3	-0.7	0.1	-0.9	1.1
Mineral and other dietary supplements	1.0	1.3	4.4	-2.0	-1.0	2.1	0.4	0.7	-0.9	-0.0	-0.1	1.0
Breast cancer (self-reported)	1.0	1.2	2.5	1.6	0.5	-1.2	-1.0	0.4	1.6	1.3	0.2	1.1
Asthma (self-reported)	0.1	0.2	0.9	-0.1	0.5	0.4	-1.0	-0.4	0.7	-0.1	0.1	-0.0
Osteoporosis (self-reported)	0.9	1.2	3.8	0.4	-1.0	-1.3	-0.9	-0.5	-1.9	-1.5	-0.5	0.3
Osteoarthritis (self-reported)	0.3	0.4	2.0	-1.4	-0.5	0.3	0.4	0.0	-0.6	-0.4	-0.1	0.3
Medication: Aspirin	0.9	1.2	5.5	-0.3	-0.4	-2.3	-0.8	-1.0	-0.6	-1.3	-0.7	-0.5
Medication: Gliclazide	1.2	1.3	3.7	-1.8	1.2	-1.9	-0.7	-0.6	1.1	-0.4	-0.3	-1.0
Illnesses of father: None of the above (group 1)	0.8	1.0	2.9	1.0	0.9	0.8	0.0	1.0	0.7	1.7	-1.0	1.0
Smoking status: Current	1.2	1.9	6.4	2.5	1.0	-1.2	1.3	-0.9	0.9	1.2	-1.1	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	3.9	-0.6	1.3	1.9	-1.3	0.8	2.0	-0.8	0.7	0.1
Whole body water mass	0.4	2.4	7.3	-0.3	-2.0	-1.1	-0.2	1.8	-2.0	0.5	2.7	0.9
Leg predicted mass (right)	0.3	1.6	4.9	-0.1	-1.4	-1.7	-0.2	1.1	-1.7	0.4	2.2	0.9
Arm fat mass (left)	0.4	1.6	6.5	-0.6	-1.7	-2.5	-0.2	-0.5	-2.0	0.1	0.5	0.4
Number of self-reported non-cancer illnesses	0.4	0.7	1.9	-0.4	-0.8	-1.4	-0.3	-0.3	-0.9	0.7	0.5	1.4
Average weekly champagne plus white wine intake	0.4	0.6	3.1	0.4	-0.0	-1.3	0.4	-0.4	0.2	1.7	-0.0	-0.1
Miserableness	1.5	2.6	6.5	-1.9	-1.6	1.1	-1.3	-0.1	-2.4	-1.2	-2.5	0.2
Guilty feelings	1.0	1.5	6.3	-0.3	-2.1	0.8	0.1	-0.6	-2.5	-1.0	-0.4	0.4
Wears glasses or contact lenses	1.5	1.7	5.7	0.8	-2.0	-1.5	0.1	-1.5	-2.4	0.1	0.2	-0.1
Ever taken oral contraceptive pill	2.0	2.2	6.4	0.2	1.1	0.5	2.5	0.7	0.5	2.1	2.1	1.6
Hearing aid user	1.3	1.5	4.2	1.4	-0.5	-1.7	1.4	0.2	0.1	2.1	0.2	1.4
Mother’s age at death	0.2	0.3	0.7	-0.8	-0.3	0.3	0.6	0.8	0.0	0.2	0.6	-0.8
Financial situation satisfaction	0.7	0.8	4.7	0.1	0.2	2.2	0.8	-0.3	0.5	0.5	1.2	0.3
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.3	-0.3	-0.5	0.1	-1.0	-0.0	0.5	-0.2	-1.1	-0.7
Commuting to job workplace: Public transport	0.7	0.9	3.6	0.3	1.6	0.0	1.0	-0.7	1.9	0.4	-0.1	-0.0
Eye problems/disorders: Glaucoma	1.2	1.4	6.4	0.2	-0.7	0.6	-0.3	-1.4	-0.1	-2.5	0.5	-1.8
Medication: Blood pressure	1.3	2.5	5.4	0.0	-1.9	-1.0	-1.2	-2.3	-1.4	-1.6	-1.7	-1.9
Pain type(s) experienced in last month: Hip pain	1.2	1.5	6.7	0.2	-2.6	-2.0	-0.4	-0.2	-1.3	-0.2	-0.4	-0.7
Supplements: Fish oil (including cod liver oil)	1.6	2.2	6.1	2.5	1.8	-2.0	0.6	-0.1	1.8	0.4	1.3	-0.6
High cholesterol (Self-reported)	0.4	0.7	2.4	-0.7	0.2	-1.5	-0.7	-1.3	0.3	-0.1	-0.6	-0.9
Medication: Bendroflumethiazide	1.3	2.0	8.8	-0.1	-2.6	-0.2	-0.6	0.2	-3.0	-0.8	-0.4	1.0
Medication: Paracetamol	0.9	1.4	5.5	-0.5	-2.4	0.1	-0.1	0.1	-2.4	-0.5	0.8	-0.5
Medication: Lisinopril	0.5	0.6	1.6	-0.7	-0.3	0.3	1.2	-0.3	-1.3	-0.4	0.5	1.1
Medication: Atorvastatin	0.1	0.2	1.0	-0.2	-0.2	0.0	-0.3	-0.3	0.3	-1.0	0.1	-0.5
Illnesses of father: High blood pressure	0.1	0.1	0.5	-0.4	0.4	0.3	-0.0	0.2	0.1	-0.4	0.7	0.4
Alcohol drinker status: Never	1.9	2.2	6.2	-1.2	-1.2	0.6	-0.8	-1.6	-2.2	-2.5	-0.7	-1.5
Ever smoked	0.9	1.7	3.6	1.2	0.8	-0.7	1.5	-1.9	0.5	1.2	-1.6	1.6
Basal metabolic rate	0.4	2.2	6.5	-0.4	-2.1	-1.3	-0.2	1.4	-2.2	0.3	2.5	0.7
Leg fat percentage (left)	0.5	1.7	4.4	-1.8	-2.1	-1.3	-0.7	-1.4	-1.7	-0.4	-0.8	-0.3
Arm fat-free mass (left)	0.5	2.5	6.7	-0.7	-2.5	-0.9	-0.3	1.8	-2.1	0.4	2.6	0.6
Number of operations (self-reported)	1.2	1.7	3.5	1.6	-1.9	-0.8	-0.4	0.9	-1.7	1.5	0.4	1.6
Average weekly beer plus cider intake	0.4	0.5	1.5	0.7	0.6	1.1	1.0	-1.2	0.1	-0.0	-0.3	0.2
Irritability	0.9	1.6	6.7	-0.3	0.8	-1.4	-0.4	-2.1	0.1	-0.3	-2.6	-0.3
Risk taking	1.1	1.6	6.7	1.3	0.2	-1.0	1.5	-0.1	-0.3	2.6	1.5	0.9
Ever had prostate specific antigen (PSA) test	0.4	0.5	2.0	0.3	0.7	0.1	-0.5	0.8	0.6	0.4	0.7	1.4
Fractured/broken bones in last 5 years	1.6	2.1	7.1	-1.0	0.9	0.6	0.5	-2.0	0.2	-2.7	-0.2	-2.2
Age started oral contraceptive pill	0.3	0.3	1.6	-0.4	-0.4	-0.1	-0.1	0.9	-0.5	-0.0	-0.3	-1.2
Diastolic blood pressure, automated reading	0.1	0.3	1.0	0.5	-0.5	-1.0	0.7	-0.6	-0.4	-0.0	-0.5	-0.2
Ever depressed for a whole week	1.7	2.1	5.6	-2.2	0.2	2.1	-1.3	-1.0	-0.3	-2.4	-0.6	-1.2
Unable to work because of sickness or disability	2.8	3.7	8.8	-3.0	-2.6	2.5	-1.8	-0.9	-2.0	-1.6	0.7	-0.2
Commuting to job workplace: Cycle	0.6	0.7	1.6	-0.6	-0.1	1.0	-1.2	1.3	-0.8	0.2	-0.1	-1.2
Myopia	0.4	0.6	2.3	0.6	0.5	0.3	1.2	-0.7	-0.1	0.5	1.5	0.7
Vascular/heart problems diagnosed by doctor	0.3	0.7	2.6	-0.3	1.6	1.4	-0.0	0.4	1.3	0.0	0.2	-0.3
Cholesterol lowering medication	1.1	1.6	5.9	-1.0	0.5	-0.0	-1.0	-1.5	0.2	-1.6	-2.4	-1.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.6	0.1	0.7	-1.1	1.3	-1.0	0.4	0.0	0.5	-0.7
Pain experienced in last month	0.6	1.0	3.3	1.0	1.0	1.0	-0.1	-0.2	0.9	-1.1	0.4	-1.8
Supplements: Calcium	1.2	1.3	3.8	1.2	-0.8	-0.8	0.5	-0.6	-1.9	-1.4	-0.8	-1.4
Basal cell carcinoma (self-reported)	0.3	0.3	1.2	0.6	-0.1	0.3	1.1	0.8	-0.0	0.6	-0.5	0.4
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.4	-0.7	-0.2	0.3	1.1	0.3	-0.5	-0.2	1.2	0.5
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.7	-1.3	-0.5	0.4	-1.0	-0.4	-1.1	-1.2	0.2	-0.2
Heart disease (siblings)	0.4	0.5	2.1	-0.4	0.8	-0.2	1.4	-0.7	0.5	0.4	0.6	0.0
Alcohol drinker status: Previous	0.8	0.9	2.5	-1.6	-0.3	1.2	-0.6	0.7	0.1	0.7	-1.6	0.5
Pack years of smoking	0.9	1.3	3.4	-0.5	1.2	-1.8	0.7	1.0	1.3	1.6	-0.6	1.1
Impedance of whole body	0.3	1.4	4.1	0.1	2.0	1.1	-0.2	-0.2	1.9	0.0	-1.9	-0.8
Leg fat mass (left)	0.4	1.5	4.4	-1.4	-2.1	-1.7	-0.8	-0.5	-1.9	-0.3	0.3	0.1
Arm predicted mass (left)	0.5	2.3	6.2	-0.7	-2.5	-1.4	-0.2	1.5	-2.1	0.3	2.3	0.3