TWAS hub - RASGRP3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.244	0.0420	3.9e-10	0.052	0.107	0.121	0.150	0.139	5.9e-07	5.9e-13	1.5e-14	7.6e-18	1.3e-16
2	GTEx	Adrenal Gland	0.311	0.1091	6.6e-03	0.232	NA	0.180	NA	0.229	7.8e-09	NA	4.9e-07	NA	9.7e-09
3	GTEx	Artery Tibial	0.162	0.0636	7.8e-03	0.036	NA	-0.001	NA	0.025	7.7e-04	NA	3.6e-01	NA	4.3e-03
4	GTEx	Colon Transverse	0.221	0.0730	2.8e-03	0.177	NA	0.183	NA	0.170	8.3e-09	NA	4.5e-09	NA	1.7e-08
5	GTEx	Esophagus Mucosa	0.460	0.0640	2.9e-11	0.288	NA	0.228	NA	0.264	1.7e-19	NA	2.8e-15	NA	8.5e-18
6	GTEx	Esophagus Muscularis	0.330	0.0680	2.6e-05	0.144	NA	0.094	NA	0.159	4.5e-09	NA	2.5e-06	NA	6.7e-10
7	GTEx	Heart Atrial Appendage	0.544	0.0720	9.6e-08	0.393	NA	0.294	NA	0.397	7.6e-19	NA	1.2e-13	NA	4.6e-19
8	GTEx	Heart Left Ventricle	0.259	0.0761	8.8e-04	0.131	NA	0.085	NA	0.087	1.9e-07	NA	2.8e-05	NA	2.3e-05
9	GTEx	Lung	0.288	0.0544	2.5e-07	0.240	NA	0.227	NA	0.224	2.5e-18	NA	2.6e-17	NA	4.5e-17
10	GTEx	Muscle Skeletal	0.219	0.0466	1.2e-06	0.194	NA	0.162	NA	0.173	1.1e-18	NA	1.2e-15	NA	9.6e-17
11	GTEx	Nerve Tibial	0.371	0.0570	4.8e-10	0.199	NA	0.191	NA	0.189	4.2e-14	NA	1.6e-13	NA	2.2e-13
12	GTEx	Skin Sun Exposed Lower leg	0.318	0.0570	9.9e-08	0.194	NA	0.179	NA	0.190	6.4e-16	NA	1.0e-14	NA	1.2e-15
13	GTEx	Spleen	0.582	0.1210	7.9e-04	0.286	NA	0.138	NA	0.159	4.8e-08	NA	2.2e-04	NA	6.9e-05
14	GTEx	Stomach	0.240	0.0820	9.4e-03	0.156	NA	0.114	NA	0.112	6.6e-08	NA	4.3e-06	NA	5.3e-06
15	GTEx	Testis	0.335	0.0920	5.6e-04	0.046	NA	0.153	NA	0.090	4.1e-03	NA	2.7e-07	NA	8.3e-05
16	GTEx	Thyroid	0.472	0.0560	2.0e-15	0.403	NA	0.401	NA	0.432	8.0e-33	NA	1.0e-32	NA	7.4e-36
17	METSIM	Adipose	0.133	0.0293	2.5e-08	0.117	0.067	0.126	0.124	0.136	4.8e-17	3.3e-10	2.7e-18	4.0e-18	9.5e-20
18	ROSMAP	Brain Pre-frontal Cortex	0.253	0.0455	1.3e-11	0.112	0.095	0.133	0.130	0.140	3.0e-14	2.9e-12	9.0e-17	2.5e-16	1.5e-17
19	TCGA	Testicular Germ Cell Tumors	0.226	0.0800	2.3e-03	0.008	0.086	0.035	NA	0.036	1.6e-01	6.0e-04	2.1e-02	NA	2.0e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Medication: Omeprazole	6.5	7.8	12.7	-0.6	3.0	3.0	3.4	3.2	3.6	2.9	2.8	2.8	2.9	2.9	3.0	2.2	2.7	-1.3	3.1	3.3	2.6	1.8
Osteoporosis (self-reported)	5.5	6.9	12.2	-1.7	2.7	3.0	2.6	2.2	2.8	2.4	2.5	3.0	2.9	2.8	2.8	2.7	2.7	0.9	2.8	2.8	3.5	1.8
Heart disease (siblings)	5.1	6.2	10.8	0.0	-2.9	-2.7	-2.7	-2.6	-2.7	-2.2	-2.4	-2.9	-2.8	-3.3	-2.6	-2.2	-2.7	-0.8	-2.5	-3.0	-2.9	-0.8
Medication: Omeprazole (e.g. Zanprol)	4.8	5.8	9.2	-0.3	2.4	2.6	2.9	2.8	3.0	2.6	2.4	2.4	2.5	2.6	2.6	2.3	2.4	-1.1	2.6	2.8	2.2	1.0
Smoking Status	4.4	10.5	15.3	-0.9	3.6	3.7	3.5	3.3	2.9	3.6	2.9	3.6	3.5	3.9	3.5	3.9	3.5	0.4	3.6	3.1	3.5	2.0
Eye problems/disorders: Diabetes related eye disease	3.6	4.0	6.5	-0.4	-2.0	-2.5	-2.4	-2.1	-2.2	-2.0	-1.9	-2.0	-2.0	-1.7	-2.1	-2.3	-2.1	-0.9	-2.3	-2.5	-2.0	-0.9
Hayfever/allergic rhinitis (self-reported)	3.5	4.7	9.8	-1.5	-2.1	-2.2	-2.4	-2.1	-3.1	-1.6	-1.6	-2.4	-2.2	-2.5	-2.2	-1.4	-2.3	1.5	-2.3	-2.5	-2.0	-2.2
Rheumatoid Arthritis	3.3	4.6	6.7	-0.8	1.7	2.6	2.1	2.0	1.7	2.0	1.9	2.5	2.4	2.4	2.4	2.5	2.5	-0.2	2.5	2.0	2.4	2.4
Smoking status: Previous	3.3	4.9	7.8	-0.4	2.1	2.3	2.4	2.3	2.5	2.3	2.3	2.5	2.4	2.8	2.5	1.8	2.3	0.6	2.6	2.1	2.1	2.1
Supplements: Vitamin C	3.2	3.7	6.0	-0.0	-1.7	-2.0	-2.2	-2.3	-2.3	-2.2	-2.4	-1.7	-1.9	-1.8	-1.9	-2.3	-1.6	-1.0	-2.0	-2.1	-1.8	-2.0
Average weekly fortified wine intake	3.0	3.5	6.2	-1.8	1.6	1.8	2.1	1.8	1.7	2.1	1.8	1.9	1.8	1.8	1.8	2.2	1.4	0.6	1.9	2.3	1.8	2.5
Past tobacco smoking	2.9	5.3	8.9	1.0	-2.0	-2.5	-2.4	-2.2	-2.4	-2.4	-2.3	-2.5	-2.5	-3.0	-2.4	-2.5	-2.4	-0.2	-2.7	-2.2	-2.5	-2.2
Medication: Co-codamol	2.4	2.8	4.0	-1.0	-1.7	-1.9	-1.6	-1.7	-1.9	-1.6	-1.4	-1.9	-1.9	-1.4	-1.8	-2.0	-1.9	0.4	-2.0	-1.3	-1.7	-1.7
Supplements: Zinc	2.1	2.2	6.0	-2.4	1.4	1.4	1.4	1.4	1.1	1.6	1.6	1.6	1.6	1.7	1.6	1.4	1.5	0.9	1.6	1.3	1.3	1.0
Ever smoked	2.1	3.8	7.2	-1.5	1.4	2.2	1.9	1.7	1.6	1.9	1.7	1.9	1.9	2.6	1.9	2.7	1.8	0.4	2.2	1.9	2.4	2.1
Medication: Levothyroxine sodium	2.0	3.4	9.8	2.5	-2.1	-1.7	-1.8	-1.5	-1.7	-1.4	-0.8	-1.8	-1.8	-1.3	-1.8	-2.0	-1.8	-3.1	-1.7	-2.0	-1.6	-1.3
Commuting to job workplace: Public transport	2.0	2.4	4.0	-1.1	2.0	1.6	1.6	1.9	1.6	1.7	1.5	1.4	1.6	1.9	1.7	1.7	1.5	1.4	1.7	1.4	1.4	0.5
Lupus	1.9	2.9	7.8	0.8	-1.5	-2.2	-1.5	-1.6	-1.2	-2.0	-1.3	-1.8	-1.8	-2.4	-2.0	-2.8	-1.7	0.4	-1.6	-0.8	-2.0	-0.2
Chronotype (morning person)	1.9	4.3	5.8	-1.8	-2.3	-2.0	-2.4	-2.1	-2.4	-1.7	-1.9	-2.4	-2.2	-2.3	-2.3	-1.4	-2.2	0.0	-2.2	-2.4	-1.9	-2.3
Pain all over the body in last month	1.9	2.1	3.4	-0.8	1.6	1.5	1.5	1.5	1.0	1.7	1.7	1.4	1.3	1.7	1.2	1.4	1.4	0.8	1.5	1.6	1.6	1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.9	2.9	5.6	0.1	-2.1	-1.7	-1.7	-1.6	-2.0	-1.7	-2.0	-1.8	-1.8	-1.2	-1.9	-1.4	-2.0	-2.4	-1.8	-1.6	-1.3	-0.2
Hypothyroidism (self reported)	1.8	4.1	15.6	1.9	-1.6	-1.7	-1.8	-1.7	-1.0	-1.9	-1.7	-2.0	-1.9	-1.6	-1.9	-2.7	-1.9	-4.0	-1.8	-2.2	-1.9	-1.4
Had menopause	1.8	2.2	4.7	-1.1	1.4	1.4	1.8	1.4	1.3	1.3	2.1	1.6	1.5	1.1	1.5	0.8	1.8	0.3	1.6	2.2	1.5	1.4
Hypothyroidism/myxoedema (self-reported)	1.8	3.6	6.6	1.6	-1.8	-1.8	-1.9	-1.8	-1.3	-2.0	-1.5	-2.1	-2.0	-1.6	-2.0	-2.6	-2.0	-2.5	-1.9	-2.0	-1.8	-1.6
Lung FEV1/FVC ratio	1.7	8.4	26.8	-5.2	3.6	3.0	3.0	2.8	2.3	2.7	2.4	2.7	2.8	2.7	3.2	2.3	2.8	3.2	2.9	2.8	1.8	-0.6
Qualifications: O levels/GCSEs or equivalent	1.7	2.6	3.8	-0.2	-1.7	-1.9	-1.8	-1.8	-1.7	-1.9	-1.9	-1.7	-1.8	-1.9	-1.8	-1.4	-1.9	0.3	-1.7	-1.6	-1.8	-0.5
Falls in the last year	1.6	2.2	4.6	-0.1	1.6	1.8	1.5	1.5	1.2	1.8	1.5	1.5	1.8	1.6	1.5	2.0	1.5	-0.8	1.3	1.1	2.1	-0.1
Migraine (self-reported)	1.6	2.0	4.8	1.3	-2.2	-1.2	-1.6	-1.5	-1.5	-1.6	-0.8	-1.5	-1.6	-1.5	-1.7	-1.2	-1.5	-1.2	-1.5	-1.3	-0.7	-0.4
Intelligence (Savage-Jansen 2018)	1.5	4.6	9.4	0.2	2.0	2.3	2.0	2.2	2.0	2.3	2.5	2.0	2.1	2.0	2.0	3.1	2.0	1.6	2.1	2.1	2.8	2.2
Coronary Artery Disease (CAD)	1.5	1.8	3.0	1.1	-1.7	-1.3	-1.3	-1.6	-1.4	-1.5	-1.7	-1.1	-1.2	-1.0	-1.3	-1.5	-1.2	-0.5	-1.4	-1.1	-1.4	-1.3
Sitting height	1.5	11.0	16.2	-2.2	-3.9	-3.0	-4.0	-3.8	-2.9	-3.7	-3.7	-3.5	-3.5	-3.1	-3.3	-2.8	-3.6	2.0	-3.6	-4.0	-2.4	-2.9
Knee pain experienced in last month	1.5	2.3	5.9	1.3	-1.5	-1.4	-1.6	-1.5	-1.5	-1.3	-1.5	-1.7	-1.6	-1.3	-1.7	-1.1	-1.5	-0.6	-1.8	-1.6	-1.1	-2.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	7.5	-2.7	1.2	1.1	1.4	1.2	1.3	1.4	1.4	1.1	1.3	1.0	1.4	1.4	1.4	1.0	1.3	1.2	1.0	0.2
Back pain experienced in last month	1.5	2.1	4.0	-0.3	1.4	1.6	1.6	1.7	1.2	1.4	2.0	1.5	1.6	1.7	1.7	1.4	1.6	0.3	1.6	1.3	1.9	0.4
Alcohol intake versus 10 years previously	1.4	2.1	3.1	-1.4	-1.7	-1.6	-1.5	-1.4	-1.5	-1.8	-1.1	-1.7	-1.5	-1.4	-1.6	-1.3	-1.7	1.2	-1.4	-1.2	-1.2	-1.4
Neck or shoulder pain in last month	1.4	1.9	3.4	1.2	-1.7	-1.5	-1.7	-1.5	-1.3	-1.2	-0.7	-1.6	-1.6	-1.2	-1.6	-1.0	-1.7	-1.1	-1.7	-1.8	-1.0	0.1
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	6.8	-0.8	1.2	1.1	1.2	1.2	0.9	0.8	1.1	1.0	1.1	1.3	1.2	1.3	1.0	-2.6	1.3	1.2	1.0	1.1
High cholesterol (Self-reported)	1.4	2.5	4.4	-0.1	1.6	1.8	1.8	2.0	1.3	2.0	2.1	1.6	1.7	1.5	1.7	1.3	1.8	-0.5	1.8	1.5	1.6	0.7
Medication: Paracetamol	1.4	2.2	4.2	-0.2	2.0	1.6	1.6	1.7	1.1	1.4	1.3	1.6	1.6	1.9	1.6	2.0	1.5	0.5	1.3	1.7	1.6	0.2
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	5.5	-0.1	1.4	1.1	1.3	1.5	1.1	1.8	2.4	1.2	1.4	1.4	1.2	1.2	1.2	-0.6	1.2	1.1	1.2	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	2.8	-0.8	-1.1	-1.2	-1.4	-1.3	-1.2	-1.6	-1.7	-1.2	-1.2	-0.5	-1.2	-1.2	-1.3	-1.5	-1.3	-1.6	-1.4	-1.4
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	2.9	-1.7	-1.3	-1.2	-1.4	-1.3	-1.4	-1.3	-1.4	-1.2	-1.2	-1.1	-1.2	-1.2	-1.1	1.3	-1.0	-1.2	-1.0	-0.4
Breastfed as a baby	1.3	1.6	3.3	-0.6	1.2	1.2	1.4	1.6	0.7	1.8	1.4	1.1	1.2	1.0	1.4	1.8	1.2	1.5	1.1	1.2	1.1	-0.2
Qualifications: College or University degree	1.3	4.2	14.6	0.0	2.0	1.8	2.0	2.1	2.2	2.1	2.6	1.8	1.9	1.3	2.0	1.9	1.8	3.8	1.8	2.3	2.1	0.6
Mean time to correctly identify matches	1.3	2.6	13.1	-3.6	1.4	1.2	1.4	1.4	1.6	1.5	1.9	1.3	1.4	1.7	1.3	1.1	1.5	0.2	1.6	1.4	1.1	1.6
Alcohol intake frequency.	1.3	3.0	4.4	-1.4	-2.0	-2.1	-1.8	-1.7	-1.7	-1.9	-1.6	-2.0	-1.9	-1.6	-2.0	-1.4	-2.0	-0.4	-1.8	-1.4	-2.0	-1.4
Friendships satisfaction	1.3	1.6	3.0	-1.7	-1.0	-1.6	-1.0	-1.1	-1.1	-0.9	-0.7	-1.5	-1.2	-1.3	-1.2	-0.6	-1.3	1.4	-1.3	-0.9	-1.6	-1.5
Average weekly spirits intake	1.2	1.5	3.9	-2.0	1.0	1.4	1.2	1.2	0.3	1.2	0.9	1.2	1.2	1.2	1.2	1.6	1.3	0.0	1.3	1.0	1.2	1.3
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.9	4.8	0.6	-2.2	-1.7	-2.1	-1.8	-2.1	-1.6	-1.6	-1.7	-1.7	-1.7	-1.8	-1.1	-1.9	0.8	-1.9	-2.2	-1.4	-1.5
Asthma	1.2	2.4	5.2	-0.5	-1.6	-1.6	-1.3	-1.4	-1.5	-1.5	-1.6	-1.9	-1.8	-2.3	-1.8	-1.6	-1.9	0.1	-1.8	-1.0	-1.3	-1.8
Eye problems/disorders: None of the above	1.2	1.3	3.9	-1.7	0.9	1.3	0.9	0.8	1.3	1.3	0.4	1.0	0.9	1.1	0.8	1.6	0.9	2.0	1.0	0.8	1.4	0.7
Mouth/teeth dental problems: Loose teeth	1.2	1.4	2.7	-1.0	1.2	1.3	1.1	1.1	0.4	1.2	1.4	1.4	1.2	1.4	1.2	0.2	1.2	1.0	1.1	1.1	1.6	1.6
Heart disease (mother)	1.2	1.5	6.6	2.6	-1.6	-1.4	-1.2	-1.1	-1.1	-0.8	-0.7	-1.1	-1.2	-0.9	-1.3	-0.6	-1.2	-0.8	-1.2	-1.0	-1.4	0.6
Comparative height size at age 10	1.2	6.4	11.8	-1.3	-2.9	-2.1	-2.7	-2.8	-2.7	-2.2	-2.5	-3.0	-2.7	-2.8	-2.6	-1.7	-2.8	0.5	-2.9	-2.6	-1.9	-3.4
Blood Platelet Count	1.1	12.8	19.5	-1.8	4.0	4.4	3.7	3.5	3.7	2.9	2.7	4.0	3.9	4.0	3.6	4.1	3.8	-0.6	4.2	3.3	4.0	3.4
Vitamin and mineral supplements	1.1	1.5	4.0	-0.9	0.7	1.5	1.2	1.1	1.2	0.8	1.4	0.8	1.0	0.9	0.9	2.0	0.9	2.0	1.3	1.0	1.5	0.8
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	5.3	0.5	1.0	1.2	1.1	1.1	0.8	1.1	0.6	0.9	0.9	1.3	0.9	1.2	0.9	-2.3	1.1	1.2	1.1	1.4
Qualifications: CSEs or equivalent	1.1	1.4	2.5	-0.1	-1.1	-1.3	-1.2	-1.1	-0.7	-1.3	-1.5	-1.3	-1.3	-1.1	-1.2	-1.1	-1.3	-1.6	-1.1	-1.1	-1.4	-1.2
Happiness	1.1	1.4	3.2	-0.6	-1.2	-1.2	-1.1	-1.2	-0.9	-1.2	-1.2	-1.5	-1.2	-1.0	-1.4	0.1	-1.7	0.0	-1.4	-0.8	-0.6	-1.8
Birth weight of first child	1.1	2.1	3.8	0.5	-1.3	-1.3	-1.4	-1.6	-1.9	-1.7	-1.9	-1.3	-1.4	-1.3	-1.2	-1.6	-1.2	-0.5	-1.4	-1.7	-1.6	-1.6
Medication: Gliclazide	1.1	1.2	3.4	-1.2	0.8	1.1	1.3	1.1	1.8	1.2	0.7	1.2	1.1	0.8	1.2	0.5	1.0	1.9	1.1	1.1	0.7	-0.7
Commuting to job workplace: Cycle	1.1	1.3	3.9	0.3	1.2	1.0	1.0	1.0	2.0	0.8	1.6	1.2	1.1	1.3	1.3	0.9	1.2	0.1	1.3	0.8	1.4	1.0
Basal cell carcinoma (self-reported)	1.1	1.3	2.7	1.6	-1.0	-0.8	-1.3	-1.1	-1.2	-1.0	-0.8	-1.3	-1.2	-1.3	-1.2	-0.5	-1.1	-1.0	-1.3	-1.3	-0.4	-1.2
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.0	-1.7	1.3	1.1	1.2	1.3	0.2	1.4	1.5	1.1	1.2	1.4	1.2	-0.1	1.2	-0.1	1.3	0.8	0.9	1.6
Standing height	1.0	9.6	15.4	-2.3	-3.9	-2.7	-3.6	-3.5	-3.0	-3.1	-3.7	-3.2	-3.1	-2.8	-2.8	-2.0	-3.1	2.7	-3.4	-3.7	-2.2	-3.4
Blood clot in the leg (DVT)	1.0	1.3	3.1	-1.8	1.2	1.1	1.2	1.2	0.2	1.4	1.5	1.0	1.2	1.4	1.1	0.1	1.2	-0.2	1.3	0.8	1.0	1.5
Chronic bronchitis/emphysema (mother)	1.0	1.1	2.2	-0.4	0.9	1.1	1.2	1.0	1.0	0.7	1.2	0.9	1.1	1.1	1.1	1.5	1.1	-1.4	1.2	1.3	1.1	-0.2
Smoking status: Current	1.0	1.5	3.4	-1.7	1.3	1.5	1.3	1.1	0.9	1.2	0.7	1.1	1.2	1.3	1.1	1.8	1.2	0.2	1.2	1.5	1.6	0.0
Medication: Atorvastatin	1.0	1.2	2.3	-0.1	1.1	1.1	1.2	1.1	1.5	1.3	1.5	1.0	1.0	1.2	1.1	1.3	1.0	-0.5	1.0	1.2	1.3	0.5
Supplements: Calcium	1.0	1.1	3.9	-2.0	0.9	1.1	0.9	0.7	1.2	0.9	0.9	1.1	1.1	1.0	1.1	0.6	0.9	-1.0	1.0	1.1	1.4	-0.6
Verbal and Numeric Reasoning (VNR)	0.9	2.2	9.6	-0.9	0.7	1.3	0.8	1.1	1.2	1.6	1.6	1.2	1.1	1.2	1.0	1.9	0.9	3.1	1.0	0.8	1.9	2.2
Time employed in main current job	0.9	1.0	2.2	1.5	1.1	1.1	0.9	1.0	1.2	0.5	0.6	1.2	1.2	1.1	1.0	0.7	1.1	1.0	1.0	0.6	1.1	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	6.7	1.2	-0.9	-0.8	-1.0	-1.0	-0.7	-0.9	-1.1	-1.0	-0.9	-0.8	-1.0	-0.2	-0.8	-2.6	-0.9	-0.9	-0.8	-0.5
Body Mass Index (BMI) (2010)	0.8	1.1	2.3	1.5	-0.9	-1.4	-1.2	-1.0	-0.3	-0.8	-0.5	-1.0	-1.1	-1.3	-1.2	-1.2	-0.9	0.0	-1.3	-1.1	-1.2	-0.5
HbA1C	0.8	0.9	2.0	-0.1	-1.4	-0.7	-1.2	-1.2	-1.0	-1.3	-1.0	-0.8	-0.8	-0.6	-0.8	-0.5	-0.7	-0.5	-0.8	-1.4	-0.7	-0.8
Height	0.8	15.5	24.2	-2.6	-4.9	-3.7	-4.6	-4.4	-2.9	-4.0	-4.5	-4.3	-4.2	-3.9	-4.0	-3.7	-4.3	2.4	-4.4	-4.4	-3.2	-3.4
Current tobacco smoking	0.8	1.3	2.7	-1.7	1.3	1.5	1.3	0.9	0.9	1.1	0.7	1.0	1.1	1.1	1.0	1.6	1.0	0.3	1.1	1.4	1.5	-0.2
Alcohol usually taken with meals	0.8	1.3	2.5	-0.0	1.5	1.0	1.6	1.5	1.1	1.3	1.2	1.0	1.2	0.4	1.3	0.6	1.2	1.2	1.2	1.5	0.4	-0.4
Allergy	0.8	1.7	4.2	2.1	1.3	1.2	1.1	1.2	1.5	1.2	1.1	1.4	1.3	1.8	1.3	1.1	1.4	-0.9	1.3	0.8	1.1	1.3
Lung cancer (father)	0.8	1.0	2.6	0.0	-1.1	-1.1	-0.7	-0.9	-0.5	-1.1	-1.0	-1.1	-1.1	-1.1	-1.0	-1.1	-1.0	-0.2	-0.9	-0.5	-1.2	-1.6
Medication: Seretide 50 evohaler	0.8	0.9	2.1	0.6	-1.0	-1.1	-0.8	-1.0	-0.7	-0.9	-0.8	-1.2	-1.2	-0.9	-1.2	-0.6	-1.4	-0.9	-1.2	-0.4	-0.9	-0.6
Commuting to job workplace: Car/motor vehicle	0.8	1.0	3.9	1.4	-0.3	-0.3	-0.8	-0.6	-0.9	-0.6	-2.0	-0.6	-0.6	-0.8	-0.7	-0.4	-0.5	-1.4	-0.9	-1.1	-0.9	-1.6
Leg fat-free mass (right)	0.8	4.2	8.3	1.4	-2.2	-2.4	-2.4	-1.9	-1.8	-1.8	-1.9	-2.0	-1.9	-1.9	-1.8	-1.4	-1.9	-1.5	-2.2	-2.9	-2.3	-2.8
Leg predicted mass (right)	0.8	4.3	8.7	1.5	-2.3	-2.4	-2.5	-1.9	-1.8	-1.8	-1.9	-2.0	-1.9	-1.9	-1.9	-1.4	-1.9	-1.6	-2.2	-3.0	-2.2	-2.8
Alzheimer’s Disease (in mother)	0.7	0.8	2.0	-1.4	-0.6	-0.8	-0.9	-0.7	-1.4	-0.4	-1.0	-1.0	-0.8	-0.9	-0.9	-0.3	-0.8	-0.3	-1.1	-0.9	-0.7	-0.9
Alzheimer’s Disease (including proxy)	0.7	1.1	2.9	-1.6	-0.8	-0.4	-1.1	-1.0	-1.7	-0.7	-1.2	-1.0	-0.8	-1.0	-1.0	0.1	-0.9	-1.4	-1.0	-1.3	-0.4	-1.1
Reaction Time	0.7	1.3	13.5	-3.7	0.8	0.5	0.7	0.8	1.2	0.9	1.0	0.6	0.7	1.3	0.6	0.7	0.7	-0.3	0.9	0.8	0.4	0.6
Blood White Count	0.7	4.8	8.9	-1.3	2.6	3.0	2.4	2.5	1.5	2.1	2.0	2.4	2.5	1.9	2.6	2.4	2.6	0.6	2.5	1.7	2.8	-0.2
Systolic blood pressure, automated reading	0.7	2.2	6.2	-1.0	1.5	1.5	1.5	1.2	1.5	1.4	1.3	1.6	1.4	0.6	1.5	1.0	1.6	2.5	1.6	1.8	1.3	1.4
Angina	0.7	0.9	7.9	2.3	0.3	0.4	0.6	0.7	0.8	0.4	0.4	0.4	0.4	0.6	0.4	-0.1	0.3	-2.8	0.4	0.2	0.2	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	2.6	0.8	-1.6	-1.2	-1.5	-1.3	-1.5	-1.0	-1.3	-1.1	-1.2	-1.2	-1.3	-0.4	-1.3	1.0	-1.3	-1.6	-1.0	-1.1
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	6.7	-2.6	-0.1	-0.3	-0.0	-0.3	-0.2	-0.0	-0.3	-0.3	-0.3	-0.8	-0.3	-0.1	-0.2	2.3	-0.1	0.1	-0.4	0.2
Supplements: Glucosamine	0.7	0.9	3.9	-2.0	1.0	0.9	0.9	0.9	0.6	1.3	1.0	0.9	0.9	0.8	1.0	0.5	1.1	0.1	0.8	1.0	0.8	-0.5
Medication: Atenolol	0.7	0.9	1.9	-0.6	-1.0	-0.9	-1.0	-0.6	-0.8	-1.0	-1.1	-1.1	-1.0	-1.0	-1.1	-1.4	-1.0	0.1	-0.7	-1.2	-1.3	0.3
Leg predicted mass (left)	0.7	3.6	11.6	1.0	-2.0	-2.1	-2.2	-1.6	-1.6	-1.4	-1.6	-1.9	-1.7	-1.7	-1.6	-1.1	-1.6	-1.1	-2.0	-2.8	-2.1	-3.4
Qualifications: None of the above	0.7	1.6	2.7	-0.1	1.2	1.6	1.5	1.4	0.3	1.6	1.2	1.3	1.3	1.4	1.4	1.2	1.6	-0.8	1.4	1.1	1.2	0.9
Fluid intelligence score	0.7	1.4	5.5	-0.5	0.7	1.3	0.5	0.9	1.1	1.1	1.3	1.0	0.9	1.1	0.8	1.7	0.7	1.1	0.9	0.5	2.1	2.4
Length of working week for main job	0.7	0.8	1.5	0.8	0.6	1.2	0.8	0.8	0.8	0.6	0.4	1.0	1.0	1.2	1.1	1.2	1.1	0.7	1.0	0.5	1.1	0.5
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.1	-0.6	-0.9	-0.8	-0.9	-0.7	-1.5	-0.8	-1.2	-0.7	-0.6	-1.0	-0.7	-0.5	-0.8	1.2	-0.8	-0.9	-0.9	-1.4
Arm fat-free mass (right)	0.7	3.8	10.8	0.4	-2.3	-2.2	-2.3	-1.7	-1.5	-1.4	-1.4	-2.2	-1.9	-2.1	-1.9	-1.0	-2.0	-1.0	-2.1	-2.5	-2.0	-3.3
Angina (self-reported)	0.7	0.9	9.1	2.5	0.2	0.3	0.5	0.5	0.6	0.3	0.4	0.2	0.3	0.4	0.2	-0.3	0.1	-3.0	0.2	0.1	0.1	0.4
Family relationship satisfaction	0.7	0.9	3.4	-1.1	-0.7	-1.1	-0.8	-0.6	-1.0	-0.6	-0.5	-0.9	-0.7	-0.5	-0.7	-0.2	-0.8	1.9	-0.8	-1.0	-1.2	-1.7
Illnesses of siblings: Diabetes	0.7	0.8	2.7	-0.9	0.8	1.0	0.8	0.9	1.5	0.8	1.2	0.6	0.8	0.6	0.6	0.9	0.6	0.4	0.8	1.1	1.6	0.0
Whole body fat-free mass	0.7	3.9	11.6	0.6	-2.3	-2.2	-2.3	-1.7	-1.7	-1.5	-1.6	-2.0	-1.8	-2.0	-1.7	-1.2	-1.8	-0.8	-2.1	-2.6	-2.1	-3.4
Asthma (self-reported)	0.7	1.4	3.1	-0.6	-1.1	-1.1	-0.9	-0.9	-1.2	-1.0	-1.1	-1.5	-1.4	-1.8	-1.4	-1.1	-1.4	0.2	-1.4	-0.6	-0.9	-1.7
Hearing aid user	0.7	0.8	2.9	-1.7	1.1	1.1	1.0	0.8	0.3	0.8	0.8	0.5	0.6	0.7	0.7	0.8	0.6	1.4	0.7	0.9	1.0	-0.1
Medication: Bendroflumethiazide	0.7	1.1	3.6	-0.2	-1.0	-1.1	-1.0	-0.8	-0.8	-1.0	-0.4	-1.2	-1.0	-1.4	-1.1	-1.4	-1.1	-0.5	-1.1	-0.9	-1.0	-1.9
Basal metabolic rate	0.7	4.0	12.5	0.9	-2.3	-2.2	-2.3	-1.7	-1.7	-1.5	-1.7	-2.0	-1.8	-1.9	-1.8	-1.1	-1.8	-0.9	-2.1	-2.6	-2.1	-3.5
Fractured/broken bones in last 5 years	0.7	0.9	2.9	0.5	-0.7	-0.6	-1.1	-1.1	-1.0	-1.0	-0.8	-1.1	-0.9	-0.9	-1.1	-0.3	-0.9	0.3	-1.2	-1.0	-0.1	-1.7
Age started oral contraceptive pill	0.7	0.9	2.2	-0.1	0.9	0.9	1.1	0.6	1.0	0.7	1.1	1.2	1.0	0.3	1.0	0.5	1.1	1.1	1.0	1.5	1.1	0.4
Ever depressed for a whole week	0.7	0.9	1.8	-0.6	-1.3	-0.8	-1.0	-0.7	-1.0	-0.8	-0.7	-1.1	-0.9	-0.6	-1.0	-0.6	-1.0	-1.3	-1.0	-1.2	-0.4	-1.0
Worry (Nagel 2018)	0.6	1.3	2.3	-1.5	1.3	1.2	1.4	1.3	0.6	1.3	1.0	1.2	1.2	1.1	1.2	1.1	1.1	-0.1	1.2	1.2	0.8	1.1
Bipolar Disorder (2011)	0.6	0.6	1.3	0.4	-0.9	-1.0	-0.7	-0.6	-0.8	-0.4	-0.9	-1.0	-1.0	-0.8	-0.8	-0.1	-0.8	-0.0	-1.1	-0.6	-0.9	0.0
Neuroticism (2016)	0.6	0.9	2.4	-1.0	0.6	0.6	0.9	1.3	0.8	1.1	1.1	0.9	0.9	1.1	1.1	0.3	0.9	1.6	1.0	0.6	-0.1	0.9
Allergy or Eczema	0.6	1.7	6.1	-1.7	-0.9	-0.9	-1.1	-1.2	-1.5	-1.0	-1.3	-1.1	-1.0	-1.6	-1.0	-0.5	-1.1	1.8	-1.2	-1.0	-0.9	-2.5
Type 2 Diabetes (T2D) (2018)	0.6	1.1	2.2	-0.5	1.3	1.1	1.2	1.1	1.1	1.0	0.7	1.1	1.2	0.9	1.3	0.9	1.1	1.5	1.1	0.9	1.0	-0.5
Medication: Metformin	0.6	0.9	2.8	-1.7	0.9	0.6	1.0	0.9	1.3	1.0	0.5	0.9	0.8	0.4	1.0	0.2	0.8	1.6	0.9	0.9	0.4	-0.6
Severe depression (siblings)	0.6	0.7	5.0	-2.2	-0.6	-0.5	-0.5	-0.5	-0.4	-0.5	-1.0	-0.3	-0.4	-0.1	-0.3	-0.7	-0.5	1.1	-0.4	-0.5	-0.6	-1.4
Leg fat-free mass (left)	0.6	3.4	11.0	1.0	-1.9	-2.0	-2.1	-1.5	-1.5	-1.4	-1.6	-1.8	-1.6	-1.6	-1.6	-1.0	-1.6	-1.1	-1.9	-2.7	-2.0	-3.3
Had other major operations	0.6	0.7	1.9	0.1	-0.7	-1.2	-0.7	-0.8	-1.0	-1.2	-0.5	-0.7	-0.8	-0.7	-0.7	-1.4	-0.7	-1.2	-0.8	-0.4	-0.9	0.1
Weight	0.6	2.9	10.9	1.9	-1.7	-1.7	-1.9	-1.3	-1.5	-1.3	-1.4	-1.6	-1.4	-1.4	-1.5	-0.7	-1.4	-1.0	-1.8	-2.2	-1.6	-3.3
Trunk fat-free mass	0.6	3.4	12.7	0.1	-2.2	-2.0	-2.0	-1.5	-1.6	-1.3	-1.5	-1.9	-1.7	-1.9	-1.6	-1.3	-1.7	-0.4	-1.9	-2.4	-2.0	-3.6
Trunk predicted mass	0.6	3.2	12.5	0.1	-2.1	-1.9	-2.0	-1.4	-1.5	-1.2	-1.4	-1.8	-1.6	-1.8	-1.5	-1.1	-1.7	-0.3	-1.9	-2.3	-1.9	-3.5
Medication: Paracetamol	0.6	1.0	2.1	-0.8	1.4	1.0	1.1	1.1	0.2	0.9	0.8	1.1	1.1	1.5	1.1	1.2	1.2	0.5	0.9	1.1	0.8	-0.0
Pulse wave peak to peak time	0.6	0.8	1.5	-0.6	-0.8	-0.9	-0.9	-0.9	-0.8	-1.1	-0.9	-0.7	-0.8	-1.1	-0.7	-1.2	-0.6	1.1	-0.8	-0.8	-1.0	-0.6
Shortness of breath walking on level ground	0.6	0.7	2.1	0.4	0.9	0.9	0.6	0.8	0.9	0.7	1.0	0.7	0.7	0.8	0.8	0.6	0.8	-1.5	0.8	0.4	1.0	1.0
Medication: Ibuprofen	0.6	0.7	4.1	1.1	-0.5	-0.5	-0.6	-0.8	-0.4	-0.8	-1.0	-0.8	-0.7	-0.6	-0.8	0.4	-0.7	-2.0	-0.7	-0.4	-0.2	-0.8
Whole body water mass	0.6	3.7	11.4	0.5	-2.2	-2.1	-2.2	-1.6	-1.6	-1.4	-1.5	-2.0	-1.8	-2.0	-1.7	-1.2	-1.8	-0.9	-2.0	-2.6	-2.1	-3.4
Medication: Lisinopril	0.6	0.7	2.1	-0.4	0.8	0.2	0.8	1.1	0.6	1.3	1.4	0.8	0.8	0.6	0.9	-0.1	0.9	1.3	0.8	0.8	-0.0	0.4
Arm fat-free mass (left)	0.6	3.0	8.8	0.2	-2.2	-2.0	-2.0	-1.4	-1.4	-1.3	-1.3	-2.0	-1.7	-1.9	-1.7	-0.8	-1.7	-0.8	-1.9	-2.1	-1.7	-3.0
Arm predicted mass (left)	0.6	3.0	8.4	0.5	-2.2	-1.9	-2.0	-1.5	-1.3	-1.3	-1.3	-1.9	-1.7	-1.9	-1.7	-0.8	-1.7	-1.0	-1.9	-2.1	-1.7	-2.9
Neuroticism (Nagel 2018)	0.5	1.2	2.2	-1.1	1.5	1.1	1.2	1.3	0.8	1.1	0.9	1.2	1.2	1.2	1.2	1.2	1.1	0.4	1.1	0.9	0.9	0.5
Ovarian Cancer	0.5	0.7	6.9	0.1	-0.6	-0.6	-0.3	-0.4	-0.6	-0.3	-0.3	-0.7	-0.6	-0.9	-0.6	0.2	-0.5	1.1	-0.7	0.0	-0.5	-2.6
Fasting Glucose	0.5	0.6	2.2	0.9	-0.9	-1.0	-0.8	-0.5	-0.6	-0.9	-0.5	-0.5	-0.5	-0.5	-0.5	-1.5	-0.6	0.6	-0.8	-0.9	-0.7	-0.2
Primary Biliary Cirrhosis	0.5	0.7	2.6	1.2	1.0	0.5	0.6	0.6	1.6	0.5	0.7	1.1	0.9	1.0	0.8	0.2	0.7	-0.1	0.8	0.5	0.6	0.9
Blood Red Count	0.5	4.8	7.0	2.5	-2.5	-2.5	-2.3	-2.1	-2.6	-2.2	-2.4	-2.1	-2.1	-1.8	-2.2	-1.9	-1.8	-1.4	-2.3	-2.1	-2.5	-1.7
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.4	-0.6	-0.6	-0.8	-1.0	-0.7	-0.4	-0.6	-0.7	-0.9	-0.7	-0.3	-0.8	0.0	-0.9	1.0	-0.9	-1.4	-0.6	-1.6
Diabetes (mother)	0.5	0.6	1.2	-0.7	-0.8	-0.9	-0.7	-0.4	-1.0	-0.6	-0.5	-0.8	-0.8	-1.1	-0.8	-0.9	-0.5	-0.4	-0.9	-0.9	-0.8	-0.9
Townsend deprivation index at recruitment	0.5	0.6	1.9	0.5	-0.9	-1.0	-0.8	-0.8	-0.2	-0.3	-0.8	-0.7	-0.8	-0.6	-1.0	-0.5	-0.8	1.4	-1.0	-0.7	-0.6	0.9
Hayfever, allergic rhinitis or eczema	0.5	1.2	5.6	-1.9	-0.7	-0.8	-0.7	-0.8	-1.2	-0.8	-0.8	-0.9	-0.7	-1.4	-0.7	-0.3	-0.8	2.4	-0.8	-0.6	-0.7	-1.4
Chronic bronchitis/emphysema (father)	0.5	0.5	1.4	0.8	-0.8	-0.8	-0.4	-0.6	-0.4	-0.5	-0.8	-1.0	-0.8	-1.2	-1.0	-0.2	-1.0	-0.6	-0.9	0.1	-0.5	0.5
Medication: Ventolin 100micrograms inhaler	0.5	0.7	2.8	-0.8	-0.5	-0.7	-0.0	-0.4	-0.2	-0.3	0.0	-1.0	-0.8	-1.3	-0.8	-1.0	-0.7	1.7	-0.9	0.6	-0.5	-1.3
Exposure to tobacco smoke outside home	0.5	0.7	1.8	0.7	0.5	0.8	0.7	1.0	0.9	0.9	1.2	0.5	0.7	0.8	0.5	0.8	0.7	-1.3	0.8	0.7	0.9	1.3
Medication for pain relief, constipation, heartburn	0.5	0.9	1.4	-0.7	-1.2	-0.9	-1.1	-1.0	-0.7	-0.9	-0.9	-1.0	-1.0	-1.0	-1.0	-0.7	-1.1	0.8	-1.0	-1.1	-0.6	-0.7
Medication: Allopurinol	0.5	0.7	1.5	0.9	-0.8	-0.8	-1.0	-0.7	-0.8	-0.5	-0.3	-1.1	-1.0	-0.5	-1.1	-0.0	-1.0	-0.5	-1.1	-0.9	-0.2	-1.2
Arm predicted mass (right)	0.5	2.8	8.8	0.3	-2.1	-1.9	-1.9	-1.4	-1.2	-1.1	-1.2	-1.9	-1.6	-1.7	-1.6	-0.7	-1.7	-1.1	-1.8	-2.0	-1.7	-3.0
Chest pain or discomfort	0.5	0.7	3.1	1.5	-0.2	-0.7	-0.5	-0.3	-0.5	-0.1	-0.4	-0.8	-0.7	-0.8	-0.8	-0.1	-0.9	-1.3	-0.8	-0.7	-0.7	-1.8
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.7	-0.4	0.7	0.9	0.6	0.7	1.3	0.5	0.9	0.7	0.6	1.0	0.6	0.5	0.7	-1.1	0.8	0.6	0.9	0.5
Qualifications: nursing, teaching	0.5	0.7	6.8	-0.8	-0.2	-0.5	-0.4	-0.3	-0.1	-0.4	-0.0	-0.9	-0.6	-0.8	-0.7	0.1	-0.8	2.6	-0.5	-0.3	-0.3	-1.3
Wears glasses or contact lenses	0.5	0.6	1.1	-0.7	-0.6	-0.6	-0.7	-0.7	-1.0	-0.7	-0.8	-0.7	-0.8	-0.8	-0.8	-0.7	-0.8	1.1	-0.7	-0.5	-0.9	-0.2
Crohns Disease (2017)	0.4	0.8	2.5	-0.1	0.6	0.8	0.9	0.8	1.6	1.1	1.2	0.8	0.7	0.9	0.9	0.9	0.6	0.5	0.8	1.0	0.9	0.9
Age at First Birth	0.4	0.7	3.9	2.0	-0.3	-0.9	-0.7	-0.3	-0.8	0.4	0.2	-1.0	-0.5	-0.4	-1.0	0.1	-0.9	-0.5	-0.8	-0.7	-0.7	-1.0
Respiratory disease	0.4	0.8	3.1	-0.5	-0.7	-0.8	-0.4	-0.4	-1.1	-0.6	-0.4	-1.1	-1.0	-1.6	-1.1	-0.9	-0.9	-0.1	-1.1	-0.1	-0.8	-1.8
Neuroticism	0.4	0.9	1.7	-1.0	0.9	1.0	1.0	1.1	0.6	1.2	1.0	0.9	1.0	1.0	1.0	1.3	0.9	-0.2	0.8	0.9	0.9	0.6
Hand grip strength (left)	0.4	0.9	3.1	0.9	-1.0	-0.6	-1.1	-1.3	-1.1	-1.2	-1.8	-0.5	-0.8	-1.2	-0.7	-0.7	-0.5	0.4	-1.0	-1.2	-0.9	0.4
Taking other prescription medications	0.4	0.6	2.6	-0.3	0.9	0.5	1.0	1.1	0.5	0.8	1.0	0.7	0.9	0.5	0.8	-0.3	0.6	0.2	0.7	0.8	0.0	-1.6
Age when periods started (menarche)	0.4	1.1	2.6	-0.4	0.9	1.1	0.9	1.0	0.7	0.7	0.8	1.1	1.0	1.6	1.2	1.2	1.0	-0.1	1.1	0.7	1.4	1.5
Serious illness, injury or assault to yourself	0.4	0.5	7.3	2.7	0.1	-0.5	0.0	0.2	0.2	0.3	-0.0	-0.2	-0.1	-0.5	-0.3	0.0	-0.2	0.9	-0.3	-0.1	-0.5	-0.5
Trunk fat mass	0.4	1.6	6.5	2.0	-1.2	-1.1	-1.4	-0.9	-1.4	-0.8	-1.0	-1.2	-1.0	-0.9	-1.1	-0.1	-0.9	-0.3	-1.3	-1.8	-1.1	-2.5
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.6	-0.6	-1.1	-0.8	-0.9	-0.7	-0.2	-0.2	-0.3	-1.2	-0.9	-0.3	-1.2	0.2	-1.3	-1.0	-1.0	-0.9	-0.5	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.2	-0.0	-0.8	-0.6	-0.9	-0.8	-0.7	-0.8	-1.1	-0.7	-0.7	-0.2	-0.8	-0.5	-0.9	-0.8	-1.0	-1.1	-0.5	-0.7
Noisy workplace	0.4	0.4	1.4	0.3	0.4	1.0	0.5	0.4	0.0	0.3	0.1	0.6	0.7	1.2	0.8	1.1	0.9	-0.7	0.6	0.1	0.8	0.1
Mouth/teeth dental problems: Dentures	0.4	0.6	3.0	-0.5	0.4	1.0	0.9	0.7	0.5	0.7	1.0	0.7	0.6	0.3	0.6	0.3	0.5	-0.1	0.9	1.0	0.8	1.7
Pulse wave Arterial Stiffness index	0.4	0.4	1.1	0.7	0.4	0.6	0.5	0.6	0.5	1.0	0.7	0.5	0.6	1.0	0.5	1.1	0.3	-0.8	0.5	0.4	0.8	0.4
Loud music exposure frequency	0.4	0.4	1.1	-0.1	0.7	0.5	0.8	0.8	-0.1	0.6	0.3	0.8	0.9	0.5	1.1	0.3	0.9	-0.9	0.9	0.2	-0.3	-0.6
Leg pain on walking	0.4	0.6	5.3	-1.3	0.5	0.8	0.3	0.3	-0.0	0.2	-0.1	0.2	0.4	0.8	0.2	0.6	0.3	-0.3	0.3	0.3	0.8	-2.3
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.2	-0.1	-0.6	-0.9	-0.8	-0.8	-0.4	-0.6	-0.9	-0.6	-0.7	-0.3	-0.7	-0.4	-0.6	-1.1	-0.7	-0.8	-0.8	-0.3
Eye problems/disorders: Glaucoma	0.4	0.5	1.0	0.1	0.8	0.9	1.0	1.0	0.5	0.4	0.5	0.7	0.8	0.7	0.9	0.3	0.7	-0.6	0.9	0.9	0.3	0.1
Supplements: Fish oil (including cod liver oil)	0.4	0.6	3.4	1.7	-0.3	-0.5	-0.3	-0.3	-0.1	-0.3	-0.2	-0.5	-0.5	-0.2	-0.4	-1.2	-0.6	-1.8	-0.5	-0.3	-0.5	-0.8
Illnesses of father: High blood pressure	0.4	0.5	3.3	-1.7	0.8	0.3	0.4	0.5	0.0	0.7	0.3	0.3	0.4	0.1	0.2	0.7	0.2	1.8	0.5	0.2	-0.0	-0.6
Unable to work because of sickness or disability	0.4	0.6	2.0	-0.3	-1.0	-0.6	-0.7	-0.7	-1.4	-0.4	-0.6	-0.8	-0.9	-0.4	-0.8	-0.7	-0.9	-0.2	-0.7	-1.0	-0.8	0.3
Myopia	0.4	0.6	4.6	-1.2	-0.6	-0.2	-0.3	-0.6	-0.7	-0.6	-1.0	-0.4	-0.4	-0.9	-0.5	-0.3	-0.3	2.1	-0.4	0.3	-0.2	-1.0
Alcohol drinker status: Previous	0.4	0.5	3.2	-1.2	0.4	0.2	0.5	0.4	0.6	0.5	0.4	0.5	0.5	0.3	0.3	0.6	0.5	1.8	0.5	0.7	0.0	0.9
Schizophrenia (2018)	0.3	0.5	3.5	-1.9	-0.5	-0.9	-0.6	-0.4	-0.0	-0.3	-0.5	-0.8	-0.8	-0.3	-0.8	-0.7	-0.9	-0.6	-0.6	-0.4	-0.7	0.0
Major Depression (MDD)	0.3	0.4	2.4	-0.3	-0.5	-0.3	-0.6	-0.7	-0.3	-0.9	-0.5	-0.5	-0.3	-0.2	-0.6	-0.1	-0.3	-1.0	-0.5	-0.5	0.2	-1.5
HDL Cholesterol	0.3	0.5	1.1	-1.0	1.0	0.7	0.7	0.6	0.5	0.7	0.5	0.9	0.7	0.7	0.8	0.1	0.6	-0.4	0.7	0.7	0.5	1.0
LDL Cholesterol	0.3	0.6	4.2	-2.0	0.3	0.2	0.5	0.3	-0.2	0.4	0.3	0.2	0.3	-0.5	0.3	0.1	0.4	2.0	0.3	0.5	-0.2	-0.6
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.0	-0.3	-0.4	-0.8	-0.6	-0.6	-0.6	-0.4	-0.7	-0.3	-0.4	-0.5	-0.4	-0.4	-0.5	0.3	-0.5	-0.5	-1.0	-0.9
Heel T-Score	0.3	2.7	5.0	2.2	-1.6	-2.0	-1.8	-1.9	-1.6	-1.3	-1.0	-1.7	-1.9	-1.8	-2.1	-1.2	-1.7	-0.8	-1.9	-1.1	-1.8	0.4
Systolic Blood Pressure	0.3	1.7	8.5	-1.6	1.0	1.1	1.0	0.7	1.3	0.9	0.7	1.3	1.1	0.6	1.3	0.7	1.0	2.9	1.4	1.1	1.0	1.9
Cardiovascular Disease	0.3	1.0	1.9	0.6	1.1	1.0	1.1	1.2	1.3	1.2	1.2	1.2	1.2	0.9	1.4	0.4	1.2	0.4	1.1	0.6	0.6	0.6
Lung FVC	0.3	1.7	5.9	-1.3	1.4	0.7	1.5	1.0	1.2	1.1	1.6	0.9	0.8	0.6	0.8	-0.1	0.9	-1.9	1.4	2.1	0.4	2.4
Number of treatments/medications taken	0.3	0.5	2.7	-1.2	-0.3	-0.4	-0.2	-0.1	-0.6	-0.6	-0.4	-0.6	-0.4	-0.8	-0.4	-1.2	-0.5	-0.2	-0.5	-0.2	-0.6	-1.7
Diabetes (father)	0.3	0.3	0.9	-1.0	0.5	0.7	0.3	0.2	0.5	0.4	0.2	0.7	0.5	0.7	0.6	0.4	0.5	0.8	0.6	0.1	0.9	0.0
Pack years adult smoking proportion	0.3	0.5	2.9	0.1	0.7	0.0	0.7	0.3	0.7	0.4	0.3	0.4	0.3	0.3	0.4	0.0	0.2	-1.7	0.4	1.3	0.1	1.5
Maternal smoking around birth	0.3	0.5	1.7	1.3	-0.2	-0.5	-0.5	-0.3	-0.2	-0.6	-0.8	-0.5	-0.5	-0.5	-0.5	-0.8	-0.5	-1.1	-0.4	-0.7	-0.6	-1.3
Fed-up feelings	0.3	0.5	2.8	-0.6	-0.6	-0.6	-0.8	-0.8	-1.7	-0.5	-0.6	-0.6	-0.6	-0.4	-0.6	-0.0	-0.7	-0.2	-0.8	-1.1	-0.5	-0.1
Relative age voice broke	0.3	0.4	5.7	0.9	-0.4	-0.3	-0.1	-0.2	-0.5	-0.4	-0.4	0.0	-0.0	-0.3	-0.0	-0.4	0.1	2.4	-0.2	0.0	-0.4	-0.7
Stomach or abdominal pain in last month	0.3	0.3	4.1	-0.4	0.0	-0.2	0.1	0.4	0.3	0.4	0.8	0.1	0.2	0.9	0.3	-0.1	0.1	-2.0	0.2	-0.2	-0.2	0.3
High blood pressure (mother)	0.3	0.4	1.2	1.1	0.2	0.5	0.5	0.6	1.1	0.4	0.9	0.3	0.3	0.1	0.2	0.5	0.2	0.4	0.5	0.6	0.8	0.8
Body mass index (BMI)	0.3	1.1	9.7	3.1	-0.0	-0.6	-0.3	0.2	-0.3	0.1	0.3	-0.2	-0.1	-0.3	-0.3	0.2	-0.0	-2.2	-0.3	-0.6	-0.7	-2.1
Waist circumference	0.3	1.0	8.4	1.9	-0.7	-0.7	-0.7	-0.3	-0.9	-0.4	-0.5	-0.6	-0.4	-0.6	-0.5	0.1	-0.6	-0.4	-0.7	-1.2	-0.7	-2.9
Number of incorrect matches in round	0.3	0.5	1.4	0.7	-0.4	-0.8	-0.4	-0.8	0.4	-0.9	-0.7	-0.7	-0.8	-0.4	-0.7	-1.2	-1.1	0.3	-0.7	-0.2	-0.4	-0.9
Nervous feelings	0.3	0.5	2.2	-0.5	-0.5	-0.8	-0.5	-0.5	-0.5	-0.6	-0.4	-0.8	-0.7	-0.8	-0.8	-0.7	-1.0	-1.5	-0.7	-0.4	-0.8	-0.7
Financial difficulties in last 2 years	0.3	0.4	4.1	0.5	-0.5	-0.4	-0.3	-0.1	0.3	0.1	-0.3	-0.9	-0.6	-0.1	-0.7	0.5	-0.6	-2.0	-0.4	-0.2	-0.1	0.4
Hip circumference	0.3	1.2	7.7	2.1	-0.9	-1.0	-1.0	-0.6	-0.9	-0.4	-0.5	-0.8	-0.6	-0.7	-0.7	0.0	-0.5	-0.6	-1.0	-1.3	-0.9	-2.8
Worrier / anxious feelings	0.3	0.5	1.2	0.3	0.7	0.8	0.8	0.6	0.3	0.5	0.6	0.9	0.8	0.6	0.9	0.5	0.8	-1.1	0.7	0.5	0.5	0.9
Medication: Cholesterol lowering	0.3	0.5	2.6	1.6	0.6	0.7	0.8	1.0	0.5	1.0	0.9	0.6	0.7	0.2	0.7	0.2	0.8	-0.2	0.6	0.3	0.2	-0.4
Depression (self-reported)	0.3	0.4	3.0	0.0	0.3	0.6	0.6	0.4	0.2	0.2	-0.1	0.5	0.5	1.0	0.5	0.7	0.6	-1.7	0.4	0.6	0.4	0.0
Prospective memory result	0.3	0.4	4.4	-0.3	0.5	0.7	0.6	0.3	-0.6	0.4	-0.0	0.3	0.4	-0.0	0.3	0.7	0.4	2.1	0.2	0.5	0.5	-0.4
Pulse wave reflection index	0.3	0.4	3.1	-0.4	0.1	0.3	0.4	0.2	-0.2	0.8	0.3	-0.0	0.2	0.6	0.0	1.2	0.2	-1.8	0.3	0.3	0.2	0.8
Gout (self-reported)	0.3	0.5	1.6	0.6	-0.7	-0.5	-0.7	-0.4	-0.5	-0.1	0.1	-0.9	-0.7	-0.2	-0.9	0.8	-0.8	-1.3	-0.8	-0.5	0.1	-0.8
Worry too long after embarrassment	0.3	0.4	2.2	-1.5	0.8	0.6	0.6	0.7	0.6	0.6	0.3	0.5	0.6	0.3	0.5	0.7	0.3	0.6	0.7	0.7	0.4	0.8
Number of children fathered	0.3	0.3	1.9	-0.1	-0.1	-0.5	-0.6	-0.6	-0.4	0.2	-0.1	-0.5	-0.4	-0.3	-0.5	0.5	-0.5	1.4	-0.4	-0.7	-0.4	0.8
Whole body fat mass	0.3	1.3	6.1	2.1	-1.0	-0.9	-1.1	-0.7	-1.1	-0.7	-0.8	-1.0	-0.8	-0.7	-0.9	0.1	-0.7	-0.9	-1.1	-1.5	-0.9	-2.5
Leg fat mass (right)	0.3	1.0	7.1	2.1	-0.6	-0.7	-0.7	-0.2	-0.7	-0.3	-0.5	-0.6	-0.4	-0.4	-0.5	0.3	-0.3	-1.2	-0.7	-1.1	-0.8	-2.7
Number of full sisters	0.3	0.4	1.4	1.1	0.1	-0.4	-0.5	-0.4	-0.9	-0.4	-0.6	-0.2	-0.2	0.1	-0.2	-0.5	-0.5	-0.7	-0.3	-1.2	-0.7	-1.1
Suffer from ‘nerves’	0.3	0.5	6.6	-1.1	-0.0	0.2	-0.3	-0.0	-0.6	-0.0	-0.0	0.0	0.0	0.5	-0.0	0.3	-0.0	-2.6	-0.0	-0.6	0.2	0.2
Had major operations	0.3	0.3	2.9	1.2	0.1	0.5	0.3	0.5	-0.4	0.4	0.1	0.1	0.2	-0.5	-0.0	0.5	0.5	1.7	0.0	-0.0	0.4	-0.4
Average weekly red wine intake	0.3	0.4	1.0	0.0	1.0	0.7	0.5	0.6	1.0	0.5	0.6	0.7	0.7	0.7	0.8	0.3	0.8	0.3	0.8	-0.1	0.3	0.8
Ever had bowel cancer screening	0.3	0.3	2.6	-0.5	-0.0	-0.3	-0.2	-0.4	-0.3	-0.8	-0.2	-0.5	-0.4	-0.4	-0.5	-1.6	-0.5	0.0	-0.5	0.3	-0.1	-1.0
Commuting to job workplace: Walk	0.3	0.4	2.2	-1.5	-0.9	-0.4	-0.1	-0.2	0.1	0.4	1.1	-0.5	-0.4	-0.6	-0.5	0.2	-0.6	0.7	-0.2	0.4	0.4	0.1
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	6.3	2.5	0.3	0.2	0.4	0.2	0.5	-0.2	0.1	0.3	0.4	0.2	0.3	0.2	0.4	0.8	0.0	0.3	0.3	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	3.7	-1.9	0.7	-0.8	0.3	0.3	0.1	0.7	0.8	-0.6	-0.3	-1.0	-0.4	-0.8	-0.3	0.4	0.0	0.7	-1.5	0.5
Arm fat mass (left)	0.3	1.2	7.8	2.4	-0.6	-0.8	-0.8	-0.4	-0.9	-0.3	-0.5	-0.8	-0.5	-0.7	-0.7	0.2	-0.5	-1.3	-0.9	-1.2	-0.8	-2.8
Guilty feelings	0.3	0.5	3.4	-1.9	-0.6	-0.4	-0.8	-0.5	-0.5	-0.3	0.2	-0.4	-0.4	0.2	-0.5	0.6	-0.5	0.9	-0.4	-0.9	0.1	0.7
Mother’s age at death	0.3	0.3	2.9	-1.7	-0.1	0.5	0.1	0.0	-0.5	0.0	0.4	0.3	0.3	0.2	0.3	-0.1	0.3	-0.9	0.3	-0.2	0.5	0.9
Tinnitus: Yes, now most or all of the time	0.3	0.3	2.8	-1.1	0.4	0.3	0.3	0.2	0.2	0.4	0.3	0.2	0.3	-0.2	0.3	0.9	0.0	1.7	0.5	0.1	0.2	0.6
Number of operations (self-reported)	0.3	0.4	1.6	1.3	-0.5	-0.7	-0.2	-0.1	-0.8	-0.4	-0.3	-0.5	-0.5	-0.9	-0.7	-1.0	-0.3	-0.2	-0.6	-0.2	-0.7	-0.2
Ever had prostate specific antigen (PSA) test	0.3	0.3	2.7	0.1	0.6	0.2	0.4	0.6	0.1	0.5	0.1	0.6	0.5	0.5	0.6	-0.0	0.6	1.6	0.3	0.2	-0.3	-0.4
Pack years of smoking	0.3	0.5	2.7	-0.2	0.6	-0.1	0.7	0.2	0.6	0.3	0.4	0.3	0.2	0.2	0.3	-0.2	0.1	-1.7	0.4	1.4	-0.0	1.5
Leg fat mass (left)	0.3	1.1	6.2	2.5	-0.7	-0.8	-0.8	-0.4	-0.8	-0.5	-0.6	-0.7	-0.5	-0.5	-0.7	0.3	-0.5	-1.5	-0.9	-1.2	-0.9	-2.3
Bipolar Disorder or Schizophrenia	0.2	0.5	3.3	-1.8	-0.7	-1.0	-0.5	-0.4	-0.1	0.0	-0.1	-0.7	-0.7	-0.3	-0.7	-1.0	-0.7	0.2	-0.5	-0.4	-0.8	0.6
Depressed Affect (Nagel 2018)	0.2	0.4	0.9	0.0	0.9	0.9	0.6	0.6	0.1	0.6	0.5	0.7	0.7	0.9	0.6	0.9	0.7	-0.2	0.5	0.4	0.9	-0.0
Depression (Nagel 2018)	0.2	0.3	2.6	-0.0	0.1	-0.2	-0.5	-0.4	-0.2	-0.5	-0.7	-0.4	-0.2	-0.1	-0.3	0.4	-0.2	0.1	-0.5	-0.8	-0.3	-1.6
Schizophrenia vs Biploar Disorder	0.2	0.2	1.6	0.0	0.4	0.4	0.2	0.3	1.1	-0.0	-0.2	0.0	0.2	0.3	0.1	0.6	0.1	-1.3	0.3	0.1	0.2	-0.5
Irritable Bowel Disease (IBD)	0.2	0.6	1.4	0.5	0.7	0.7	0.7	0.8	1.2	1.1	1.1	0.7	0.6	0.8	0.7	0.8	0.5	0.2	0.7	0.5	0.6	0.7
Breast Cancer	0.2	0.4	3.3	1.8	-0.4	-0.8	-0.1	-0.3	0.2	-0.2	-0.7	0.2	-0.0	0.0	-0.0	-1.1	0.0	0.2	-0.3	0.0	-1.3	-0.1
Prostate Cancer	0.2	0.2	2.8	-0.6	0.1	0.1	-0.2	-0.1	-0.1	-0.4	-0.2	-0.1	-0.1	-0.0	-0.1	-0.6	-0.1	1.7	-0.2	-0.5	-0.0	-0.2
Crohns Disease (2012)	0.2	0.3	1.4	0.3	-0.2	0.4	0.3	0.2	1.1	0.7	1.2	0.3	0.3	0.2	0.3	0.6	0.2	0.9	0.2	0.4	0.6	0.1
Mean Putamen Volume	0.2	0.3	2.2	0.2	-0.5	0.1	-0.2	-0.2	-0.1	-0.2	-0.5	-0.3	-0.2	-0.3	-0.4	0.1	-0.4	-1.5	-0.2	-0.3	0.4	1.1
Schizophrenia (2014)	0.2	0.4	5.3	-2.3	-0.1	-0.4	-0.0	0.2	0.3	0.5	0.3	-0.4	-0.2	0.0	-0.3	0.1	-0.3	-0.2	-0.0	0.0	-0.2	0.8
Ulcerative Colitis	0.2	0.3	1.4	0.6	0.2	0.1	-0.2	0.4	0.4	0.7	1.0	-0.1	0.0	-0.0	-0.2	0.8	-0.1	-1.2	-0.0	-0.3	0.4	0.9
Blood Eosinophil Count	0.2	1.4	6.1	-2.5	1.2	1.5	1.0	0.8	0.8	0.9	0.5	0.9	1.1	0.6	0.9	1.3	0.9	1.5	1.1	1.0	1.4	-1.4
BMI	0.2	1.0	9.2	3.0	0.6	-0.1	0.1	0.6	0.5	0.6	1.0	0.3	0.5	0.2	0.3	0.5	0.7	-1.3	0.0	-0.4	-0.4	-1.9
Hearing difficulty/problems: Yes	0.2	0.3	3.0	-1.7	0.0	0.5	0.4	0.0	0.5	-0.2	0.6	-0.0	0.2	0.2	-0.0	1.0	0.1	-0.4	0.4	0.8	0.8	-0.1
Relative age of first facial hair	0.2	0.4	1.4	0.2	0.4	0.8	0.6	0.3	0.5	0.3	0.1	0.6	0.5	0.8	0.6	0.6	0.8	1.2	0.6	0.8	0.8	0.5
Ever had hysterectomy (womb removed)	0.2	0.2	0.5	-0.3	0.3	0.5	0.5	0.3	0.6	0.1	0.2	0.4	0.4	0.6	0.3	0.3	0.2	-0.6	0.3	0.7	0.5	0.2
Medication for hormone replacement therapy	0.2	0.2	1.4	0.5	-0.2	-0.2	-0.0	-0.1	-0.3	-0.5	-0.8	-0.1	-0.2	-0.0	-0.1	-0.9	-0.1	-1.2	0.0	0.1	-0.6	0.5
Impedance of leg (right)	0.2	1.0	8.3	-2.4	-0.6	0.6	-0.1	-0.6	-0.8	-0.6	-1.3	-0.5	-0.5	0.1	-0.4	0.3	-0.5	2.9	-0.5	0.2	0.6	0.0
Trunk fat percentage	0.2	1.0	4.6	2.1	-0.8	-0.6	-1.0	-0.7	-1.2	-0.7	-0.8	-0.8	-0.7	-0.6	-0.9	0.2	-0.6	-0.3	-1.0	-1.3	-0.6	-1.8
Hand grip strength (right)	0.2	0.6	1.4	0.9	-0.9	-0.3	-1.0	-0.8	-1.0	-0.8	-1.2	-0.4	-0.6	-1.0	-0.5	-0.2	-0.4	0.6	-0.6	-1.1	-0.5	0.7
Multivitamins +/- minerals	0.2	0.2	0.7	-0.3	0.8	0.0	0.6	0.6	-0.1	0.7	0.1	0.7	0.6	0.3	0.6	-0.5	0.6	0.3	0.3	0.8	-0.2	-0.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	1.1	0.8	0.1	0.6	0.3	0.4	0.6	0.5	0.3	0.5	0.4	0.6	0.4	0.4	0.4	1.0	0.2	0.2	0.9	-0.3
Impedance of leg (left)	0.2	1.0	5.2	-1.5	-1.0	0.2	-0.5	-1.0	-1.1	-1.0	-1.7	-0.7	-0.8	-0.2	-0.8	0.1	-0.9	2.3	-0.8	-0.0	0.4	0.9
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	1.0	1.0	-0.9	-0.3	-0.4	-0.1	-0.4	-0.2	-0.2	-0.4	-0.2	0.1	-0.4	0.4	-0.3	-0.9	-0.5	-0.2	0.3	-0.0
Impedance of arm (right)	0.2	1.0	8.7	-1.4	0.4	1.2	0.3	-0.1	-0.6	0.1	-0.7	0.6	0.4	0.9	0.6	0.7	0.6	3.0	0.3	0.1	1.2	1.1
Arm fat percentage (right)	0.2	0.6	5.6	2.4	0.5	0.2	0.1	0.4	-0.3	0.4	0.3	0.3	0.5	0.4	0.3	0.9	0.5	-1.0	0.1	-0.4	0.1	-1.8
Father’s age at death	0.2	0.3	1.2	-0.6	0.4	0.4	0.3	0.4	-0.3	0.6	1.1	0.2	0.4	0.2	0.1	0.8	0.3	0.7	0.3	0.4	0.7	1.0
Medication: Lansoprazole	0.2	0.2	2.0	-0.3	0.4	0.3	0.1	0.3	-0.2	0.3	0.5	-0.0	0.2	0.1	0.0	0.4	-0.2	1.4	0.2	-0.2	0.3	-0.4
Illnesses of mother	0.2	0.2	2.5	-1.6	0.5	0.3	0.1	0.1	-0.1	0.3	-0.5	0.3	0.2	0.3	0.4	-0.1	0.3	-0.0	0.2	0.1	-0.2	-0.3
Arm fat mass (right)	0.2	0.9	7.3	2.0	-0.4	-0.6	-0.7	-0.2	-0.8	-0.2	-0.3	-0.5	-0.3	-0.4	-0.5	0.3	-0.3	-1.2	-0.7	-1.0	-0.6	-2.7
Exposure to tobacco smoke at home	0.2	0.3	3.6	0.8	-0.2	0.1	0.1	0.0	0.3	0.0	-0.2	0.1	-0.0	0.2	-0.0	0.4	0.0	-1.9	-0.0	-0.0	0.1	0.5
Ever highly irritable/argumentative for 2 days	0.2	0.2	1.3	-0.3	-0.4	-0.2	0.0	0.1	-0.3	0.2	0.4	-0.4	-0.2	-0.3	-0.3	1.0	0.1	-1.2	0.0	0.1	-0.1	1.1
Headache pain in last month	0.2	0.4	3.8	-0.5	-0.0	0.4	0.4	0.4	0.3	0.3	0.3	0.2	0.2	0.8	0.2	0.7	0.0	-2.0	0.2	0.6	0.7	-0.2
Glaucoma (self-reported)	0.2	0.2	0.6	-0.1	0.8	0.5	0.6	0.6	0.3	0.1	0.2	0.5	0.6	0.3	0.6	-0.1	0.5	-0.0	0.6	0.6	0.3	-0.2
Medication: Amlodipine	0.2	0.2	0.9	0.7	0.6	0.2	0.4	0.9	0.2	0.7	0.4	0.1	0.4	-0.2	0.3	-0.4	0.6	0.2	0.3	-0.2	-0.1	-1.0
Body fat percentage	0.2	0.7	5.7	2.4	-0.4	-0.4	-0.6	-0.3	-0.8	-0.3	-0.5	-0.5	-0.3	-0.2	-0.6	0.5	-0.2	-0.8	-0.7	-1.0	-0.4	-1.7
Comparative body size at age 10	0.2	0.5	6.0	1.4	0.4	0.4	0.4	0.5	0.4	0.1	0.2	0.2	0.4	0.0	0.2	0.2	0.2	-2.4	0.3	0.3	0.2	-0.9
Number of full brothers	0.2	0.2	0.6	-0.6	-0.4	-0.7	-0.4	-0.4	-0.1	0.1	-0.1	-0.5	-0.4	-0.4	-0.3	0.1	-0.5	0.5	-0.5	-0.5	-0.8	-0.8
Age at first live birth	0.2	0.4	2.6	1.2	-0.5	-0.0	-0.4	-0.2	-0.7	-0.2	-0.6	-0.2	-0.2	-0.5	-0.1	0.3	-0.3	1.4	-0.4	-0.3	0.0	-1.6
Emphysema/chronic bronchitis	0.2	0.2	2.3	0.6	0.0	0.1	0.0	-0.3	-0.0	-0.3	-0.2	0.1	-0.0	-0.2	-0.0	-0.9	0.2	-1.5	-0.0	0.1	0.2	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	1.5	1.2	-0.4	-0.1	-0.0	-0.2	0.5	-0.4	0.1	-0.4	-0.4	-0.7	-0.3	0.2	-0.6	0.2	-0.3	0.2	-0.0	-0.5
Overall health rating	0.2	0.5	7.1	0.3	0.5	0.1	0.2	0.3	-0.4	0.2	0.1	0.0	0.1	0.0	0.1	-0.4	-0.0	-1.2	-0.2	0.0	-0.1	-2.7
Age at last live birth	0.2	0.3	1.7	1.3	0.2	0.5	0.3	0.3	0.5	0.2	0.1	0.3	0.3	0.0	0.4	0.6	0.1	1.2	0.1	0.3	0.6	-1.2
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.3	-1.2	0.4	0.7	0.2	0.0	0.1	0.1	0.3	0.6	0.4	0.3	0.6	-0.2	0.3	-0.5	0.4	0.2	0.5	0.5
Medication: Aspirin	0.2	0.2	1.5	0.7	0.4	-0.0	0.2	0.2	0.3	0.4	0.8	0.4	0.3	0.0	0.4	-0.6	0.4	1.2	0.4	0.1	-0.1	0.7
Arm fat percentage (left)	0.2	0.7	6.9	2.6	0.4	0.0	-0.0	0.3	-0.3	0.4	0.1	0.1	0.3	0.3	0.1	0.9	0.4	-1.1	-0.1	-0.5	-0.1	-1.9
Mood swings	0.2	0.3	1.1	-0.1	-0.4	-0.5	-0.7	-0.5	-0.5	-0.6	-0.6	-0.4	-0.4	-0.2	-0.5	-0.6	-0.5	-0.1	-0.6	-1.0	-0.6	-0.4
Loneliness, isolation	0.2	0.2	1.3	-0.7	-0.3	-0.2	-0.2	0.2	-0.8	0.4	0.5	-0.3	-0.1	0.2	-0.2	1.1	-0.3	0.0	-0.4	-0.3	0.3	-0.7
Long-standing illness, disability or infirmity	0.2	0.3	1.3	-1.1	0.5	0.4	0.6	0.5	0.5	0.5	0.8	0.1	0.3	-0.0	0.2	0.1	0.1	1.1	0.4	0.6	0.2	-1.1
Osteoarthritis (self-reported)	0.2	0.3	4.1	-2.0	0.3	-0.1	-0.0	-0.1	0.0	-0.1	0.1	-0.1	-0.2	-0.0	-0.2	-0.4	0.1	-0.3	-0.0	0.2	-0.0	-1.0
Illnesses of father: None of the above (group 1)	0.2	0.2	3.1	0.1	-0.3	-0.2	-0.1	-0.3	-0.2	-0.1	-0.3	-0.3	-0.3	0.0	-0.2	-0.1	-0.3	-1.8	-0.2	0.1	-0.3	0.3
Number of self-reported non-cancer illnesses	0.2	0.4	4.2	-2.0	0.1	-0.1	0.2	0.3	-0.5	-0.0	-0.2	-0.3	-0.2	-0.5	-0.1	-1.1	-0.1	0.0	-0.1	0.0	-0.6	-1.1
Average weekly champagne plus white wine intake	0.2	0.3	0.8	0.6	-0.7	-0.2	-0.3	-0.1	-0.3	0.1	0.0	-0.8	-0.6	-0.9	-0.8	0.5	-0.5	-0.6	-0.6	-0.1	-0.1	0.5
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.2	0.2	0.2	0.5	-0.2	0.1	-0.7	0.4	0.2	-0.1	0.0	0.5	-0.0	0.7	-0.0	-0.1	-0.1	-0.5	0.9	-1.1
Alcohol drinker status: Never	0.2	0.2	1.3	1.0	0.1	0.1	-0.0	0.1	-0.3	0.3	0.1	-0.2	-0.2	-0.0	-0.2	0.8	-0.3	-1.1	-0.1	0.2	0.1	0.8
Leg fat percentage (left)	0.2	0.7	5.2	2.3	-0.3	-0.4	-0.4	-0.0	-0.6	-0.2	-0.3	-0.5	-0.3	-0.2	-0.5	0.4	-0.3	-1.4	-0.5	-0.7	-0.6	-1.6
Average weekly beer plus cider intake	0.2	0.3	1.3	-0.4	0.1	0.4	0.0	-0.1	0.8	0.4	0.2	0.3	0.1	0.4	0.1	0.6	0.3	-0.9	0.4	0.0	0.9	1.2
Irritability	0.2	0.3	0.9	0.5	0.4	0.4	0.1	0.1	0.5	0.4	0.5	0.7	0.6	1.0	0.7	0.2	0.7	-0.3	0.4	-0.5	-0.0	0.5
Risk taking	0.2	0.3	1.1	0.6	0.5	0.1	0.5	0.4	0.5	0.7	0.8	0.5	0.4	1.1	0.4	0.5	0.6	0.6	0.2	0.8	0.5	0.7
Impedance of whole body	0.2	1.0	9.7	-1.7	-0.2	0.9	-0.1	-0.6	-0.6	-0.5	-1.1	0.0	-0.2	0.4	-0.1	0.7	-0.1	3.1	-0.2	0.2	1.1	1.1
Bipolar Disorder (2018)	0.1	0.2	1.1	-0.5	-0.4	-0.5	-0.1	-0.0	-0.1	0.4	0.5	-0.1	-0.2	-0.1	-0.1	-0.5	0.0	1.0	-0.0	-0.2	-0.4	1.1
Alzheimer’s Disease (in father)	0.1	0.1	1.4	-1.2	-0.1	0.2	-0.2	-0.2	-0.5	-0.1	0.0	0.1	0.1	-0.2	0.1	0.3	-0.1	-0.7	0.2	-0.6	0.0	-0.2
Ulcerative Colitis (UC)	0.1	0.3	1.0	1.0	0.6	0.4	0.3	0.6	0.5	0.8	0.6	0.4	0.4	0.6	0.4	0.6	0.4	-0.2	0.4	-0.0	0.2	0.0
Triglycerides	0.1	0.1	0.8	0.6	-0.3	-0.4	-0.0	-0.1	0.2	-0.3	-0.0	0.0	-0.1	-0.4	0.0	-0.7	0.0	0.9	-0.1	-0.0	-0.6	0.0
Waist Hip Ratio (WHR)	0.1	0.5	2.3	-0.6	-0.5	0.1	-0.4	-0.3	-1.3	-0.4	-1.5	-0.2	-0.2	-0.1	0.0	-0.3	-0.7	1.3	-0.3	-1.0	-0.1	-1.1
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.8	0.1	-0.4	-0.2	0.1	-0.2	-0.2	-0.2	-0.1	-0.3	-0.2	-0.1	-0.3	-0.4	-0.2	-0.6	-0.2	0.4	-0.2	-0.9
High blood pressure	0.1	0.4	1.8	0.9	-0.5	-0.9	-0.5	-0.2	-0.2	-0.2	0.0	-0.6	-0.6	-0.8	-0.6	-1.3	-0.5	-0.7	-0.5	-0.5	-0.9	-0.3
Hearing difficulty/problems with background noise	0.1	0.1	1.3	-1.2	-0.4	0.2	0.1	0.0	-0.1	0.0	0.2	-0.3	-0.1	-0.1	-0.3	0.8	-0.1	0.1	-0.0	0.2	0.6	-0.0
Hair/balding pattern: Pattern 2	0.1	0.2	1.0	1.0	-0.2	0.1	-0.0	-0.0	0.3	0.2	-0.5	0.2	0.2	0.4	0.5	0.6	0.4	0.2	-0.1	-0.4	-0.1	-1.0
Heart attack	0.1	0.1	0.9	0.6	0.0	0.3	-0.3	0.1	-0.2	0.0	0.1	0.1	0.1	0.1	-0.0	0.2	0.1	0.2	0.0	-0.9	0.1	-0.0
Diabetes (self-reported)	0.1	0.2	2.6	-0.7	0.1	-0.2	0.1	0.1	0.1	0.2	-0.2	0.0	0.0	-0.2	0.2	0.2	0.1	1.6	0.0	-0.2	-0.3	-0.6
Medication: Ramipril	0.1	0.1	0.6	0.2	-0.4	0.0	-0.1	-0.2	-0.0	-0.5	-0.2	-0.2	-0.2	-0.6	-0.3	-0.2	-0.4	0.8	-0.2	-0.2	0.2	-0.6
Medication: Simvastatin	0.1	0.1	0.8	0.9	-0.1	0.1	0.1	0.4	-0.5	0.5	0.2	0.1	0.2	-0.0	0.2	-0.1	0.4	0.1	0.1	-0.4	-0.4	-0.5
Illnesses of siblings	0.1	0.1	0.8	0.9	0.2	0.2	0.0	-0.1	-0.2	-0.2	-0.5	0.7	0.4	0.6	0.4	-0.1	0.4	-0.5	0.2	-0.2	0.1	-0.1
Hair/balding pattern: Pattern 3	0.1	0.1	0.6	-0.4	-0.1	-0.1	0.4	0.2	0.0	0.0	0.3	0.1	0.1	-0.1	-0.1	-0.7	-0.0	0.6	0.2	0.8	-0.1	0.6
Number of live births	0.1	0.2	2.0	0.6	0.2	0.4	0.2	0.2	0.0	-0.1	0.5	-0.1	0.1	-0.1	0.0	0.3	0.1	-1.4	0.3	0.1	0.4	-0.8
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	3.0	-1.7	0.6	-0.1	0.1	0.0	0.5	0.2	0.3	-0.0	-0.0	0.0	0.2	-0.1	-0.1	0.7	0.1	0.4	-0.3	0.0
Pulse rate	0.1	0.2	0.5	0.1	-0.0	0.4	0.2	0.3	0.7	-0.2	0.2	0.6	0.4	0.6	0.4	0.0	0.2	-0.1	0.2	0.3	0.7	0.6
Qualifications: A levels/AS levels or equivalent	0.1	0.1	0.7	0.7	-0.1	-0.1	-0.2	0.1	0.5	0.1	0.3	-0.4	-0.2	-0.2	-0.2	0.7	-0.3	0.9	-0.1	-0.0	0.2	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	2.8	-1.7	0.7	0.2	0.6	0.5	0.8	0.7	0.7	0.3	0.4	0.4	0.5	0.4	0.3	0.2	0.5	1.1	0.0	0.7
Impedance of arm (left)	0.1	0.6	6.2	-1.1	0.2	0.9	0.1	-0.4	-0.4	-0.2	-0.9	0.3	0.1	0.6	0.2	0.6	0.2	2.5	0.1	0.1	1.0	0.8
Tense / ‘highly strung’	0.1	0.1	2.1	-1.4	0.0	0.1	0.1	-0.0	-0.6	0.2	0.0	0.0	0.1	0.2	0.1	-0.2	0.1	0.3	0.0	-0.2	-0.2	0.1
Peak expiratory flow (PEF)	0.1	0.3	2.1	0.0	0.8	0.5	0.3	0.2	0.8	0.4	0.1	0.3	0.3	0.4	0.4	1.4	0.3	0.6	0.2	0.5	0.6	-0.2
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	1.8	-1.3	0.2	0.1	0.1	-0.2	0.1	-0.4	-0.3	0.0	-0.0	0.4	-0.0	0.5	-0.2	-0.2	0.2	0.5	0.4	0.2
Birth weight	0.1	0.3	0.6	0.7	0.7	0.4	0.6	0.6	0.7	0.3	-0.1	0.4	0.5	0.4	0.6	0.5	0.6	0.0	0.4	0.5	-0.0	-0.8
High blood pressure (siblings)	0.1	0.2	0.6	0.0	-0.6	-0.5	-0.3	-0.1	-0.1	0.1	0.4	-0.8	-0.6	-0.3	-0.7	0.4	-0.7	0.4	-0.5	-0.0	-0.1	-0.1
Forced vital capacity (FVC), Best measure	0.1	0.2	0.9	-0.8	0.2	0.0	0.4	0.3	0.9	0.5	0.6	0.1	0.2	0.3	0.2	0.1	0.2	-0.3	0.3	0.9	0.1	0.9
Leg fat percentage (right)	0.1	0.4	4.2	1.6	0.1	0.0	0.1	0.5	-0.2	0.3	0.1	-0.1	0.1	0.1	-0.1	0.7	0.2	-0.8	-0.1	-0.3	-0.3	-2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	1.9	1.4	-0.4	-0.3	-0.1	0.0	-0.4	-0.2	-0.3	0.0	-0.1	0.2	-0.1	-0.3	-0.3	-0.1	-0.2	-0.3	-0.3	-0.1
Wheeze or whistling in the chest in last year	0.1	0.2	1.4	0.3	0.2	0.3	0.7	0.5	0.6	0.6	0.4	0.1	0.2	0.2	0.1	0.7	0.1	-0.7	0.2	1.2	0.3	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	1.0	0.4	-0.1	-0.4	-0.3	-0.5	0.3	-0.5	-0.2	0.2	-0.1	-0.2	-0.1	-1.0	0.0	0.1	-0.3	-0.3	-0.2	-0.2
Health satisfaction	0.1	0.2	1.3	-1.1	0.4	0.4	0.4	0.5	-0.2	0.2	0.2	0.2	0.4	0.5	0.3	0.2	0.3	-0.5	0.3	0.2	0.3	-0.1
Medication: Blood pressure	0.1	0.2	2.0	1.4	0.0	-0.1	0.0	0.4	0.1	0.4	0.4	0.0	0.2	-0.0	0.1	-0.3	0.2	-0.5	-0.1	-0.3	-0.0	-0.3
Pulse rate, automated reading	0.1	0.3	1.3	-1.1	-0.5	-0.2	-0.4	-0.2	-0.8	-0.8	-0.7	-0.1	-0.2	-0.2	-0.3	-0.4	-0.1	1.0	-0.2	-0.6	-0.3	-0.1
Hypertension (Self-reported)	0.1	0.2	1.9	1.4	0.2	-0.4	0.2	0.4	0.4	0.3	0.5	-0.0	0.1	-0.2	0.1	-0.9	0.2	-0.5	0.0	0.2	-0.5	-0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.2	1.2	-1.1	-0.1	0.4	0.0	0.2	-0.1	0.4	0.1	0.3	0.3	0.3	0.2	0.3	0.2	-0.1	0.4	-0.4	0.3	0.9
Illnesses of father: Heart disease	0.1	0.1	0.5	0.6	-0.1	0.2	-0.3	0.1	0.4	0.1	0.4	-0.0	-0.1	0.2	-0.1	0.0	0.1	-0.2	-0.0	-0.6	0.7	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	1.2	-0.3	-1.1	-0.5	-0.8	-0.4	-0.0	-0.2	-0.5	-0.5	-0.5	0.3	-0.3	-0.0	-0.5	0.0	-0.7	-1.0	-0.1	0.2
Diabetes diagnosed by doctor	0.1	0.2	2.6	-0.5	-0.1	-0.4	0.0	-0.1	0.2	-0.0	-0.6	-0.1	-0.1	-0.3	0.1	-0.2	-0.1	1.6	-0.1	-0.2	-0.6	-0.8
Eye problems/disorders: Cataract	0.1	0.2	0.7	0.8	-0.1	-0.4	-0.1	-0.2	-0.7	-0.4	0.2	-0.1	-0.1	-0.3	-0.0	-0.4	-0.0	-0.7	-0.1	0.1	-0.6	0.4
Medication for cholesterol	0.1	0.2	1.2	-0.8	0.3	0.3	-0.0	-0.1	0.2	0.3	0.1	0.3	0.2	0.4	0.1	1.1	0.1	1.0	-0.0	-0.1	0.5	0.1
Mineral and other dietary supplements	0.1	0.1	1.3	0.2	-0.4	-0.0	-0.1	-0.1	-0.3	-0.4	-0.2	-0.2	-0.1	-0.3	-0.2	0.6	-0.1	0.6	-0.0	-0.1	-0.1	1.1
Breast cancer (self-reported)	0.1	0.1	0.7	-0.8	-0.3	-0.1	0.0	-0.1	-0.7	-0.2	-0.2	-0.1	-0.2	-0.5	-0.1	-0.0	-0.2	0.0	-0.2	0.4	0.1	0.9
Medication: Aspirin	0.1	0.2	0.9	0.5	0.3	-0.2	0.0	0.2	0.2	0.3	0.7	0.2	0.2	-0.1	0.2	-0.7	0.3	0.9	0.2	-0.2	-0.3	0.3
Miserableness	0.1	0.2	1.1	0.5	-0.0	-0.6	-0.5	-0.2	-0.5	-0.4	-0.1	-0.1	-0.3	0.4	-0.3	-0.6	-0.2	1.0	-0.4	-0.6	-0.5	0.3
Ever taken oral contraceptive pill	0.1	0.1	0.2	0.4	-0.4	-0.5	-0.3	-0.2	-0.1	0.1	-0.3	-0.2	-0.3	-0.4	-0.2	-0.4	-0.2	-0.2	-0.2	-0.5	-0.2	-0.1
Financial situation satisfaction	0.1	0.1	0.9	-0.1	-0.0	0.1	0.1	0.1	0.1	0.2	-0.0	-0.3	-0.1	0.4	-0.1	0.4	-0.2	-0.9	0.0	-0.2	-0.2	-0.2
Medication: Blood pressure	0.1	0.2	1.8	0.0	-0.3	-0.4	-0.3	-0.2	-0.2	-0.6	-0.2	-0.4	-0.4	-0.6	-0.5	-1.3	-0.4	-0.3	-0.2	-0.1	-0.6	-0.3
Diastolic blood pressure, automated reading	0.1	0.3	0.8	-0.4	0.4	0.7	0.3	0.4	0.3	0.2	-0.1	0.6	0.5	0.4	0.5	0.9	0.5	-0.5	0.7	0.4	0.5	0.9
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.3	-1.1	0.2	0.7	0.4	-0.0	-0.0	-0.1	-0.4	0.4	0.3	0.6	0.3	1.2	0.3	0.6	0.3	0.6	0.8	-0.1
Cholesterol lowering medication	0.1	0.1	0.9	-0.9	0.1	0.0	0.2	0.1	-0.1	0.4	0.5	-0.2	-0.0	-0.2	-0.0	0.1	0.1	-0.5	0.1	0.3	0.1	-0.9
Pain experienced in last month	0.1	0.2	0.6	-0.2	0.5	-0.1	0.4	0.2	0.1	-0.1	0.0	0.4	0.3	-0.1	0.3	-0.5	0.4	0.6	0.4	0.8	-0.4	0.8
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.8	0.6	0.1	0.4	-0.2	0.2	-0.1	0.1	0.2	0.1	0.2	0.1	0.0	0.3	0.1	0.1	0.1	-0.9	0.1	0.1
Hair Pigment	0.0	0.8	2.2	0.5	-0.5	-1.1	-1.1	-0.8	-1.0	-0.7	-0.5	-0.7	-0.7	-0.4	-0.6	-1.3	-0.4	-0.5	-0.8	-1.5	-1.3	-1.1
Tanning	0.0	0.4	1.4	0.3	0.4	0.6	0.6	0.6	0.5	0.9	0.9	0.3	0.3	0.6	0.4	1.2	0.3	0.6	0.5	0.6	0.7	0.9
Sensitivity / hurt feelings	0.0	0.1	0.6	-0.0	-0.3	0.1	0.1	-0.0	0.0	-0.2	-0.4	-0.1	-0.2	-0.2	-0.2	0.0	-0.2	-0.8	-0.1	0.3	-0.1	0.1
Forced vital capacity (FVC)	0.0	0.2	1.1	-1.1	0.0	-0.3	-0.1	-0.2	0.6	0.0	0.3	-0.2	-0.2	0.0	-0.1	-0.3	-0.2	-0.0	-0.1	0.4	-0.1	0.9
Mouth/teeth dental problems	0.0	0.0	0.1	0.2	0.1	-0.1	-0.2	-0.2	0.3	0.1	-0.0	-0.1	-0.2	0.3	-0.0	0.3	-0.0	-0.1	-0.1	-0.1	0.0	0.3
Neuroticism score	0.0	0.1	0.6	-0.8	-0.2	-0.0	-0.2	0.0	-0.6	0.2	0.1	-0.1	-0.0	0.2	-0.1	0.4	-0.2	-0.6	-0.2	-0.3	-0.1	0.4
Hair/balding pattern: Pattern 4	0.0	0.1	0.7	-0.6	0.3	0.2	0.0	0.0	0.0	-0.1	0.7	0.2	0.2	-0.1	0.1	0.2	0.2	0.8	0.3	-0.2	0.2	0.4

Hub : Genes

RASGRP3

Models

Trait associations