Hub : Genes

RASL10B

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1030 0.0360 0.00015 0.036 NA 0.043 NA 0.039 5.5e-04 NA 1.8e-04 NA 3.5e-04
2 GTEx Adipose Visceral Omentum 0.1080 0.0450 0.00460 0.046 NA 0.000 NA 0.021 2.0e-03 NA 3.1e-01 NA 2.7e-02
3 GTEx Adrenal Gland 0.1833 0.0818 0.00410 -0.007 NA 0.002 NA -0.001 6.7e-01 NA 2.8e-01 NA 3.6e-01
4 GTEx Muscle Skeletal 0.0505 0.0196 0.00066 0.042 NA 0.061 NA 0.052 5.8e-05 NA 1.2e-06 NA 7.5e-06
5 GTEx Pancreas 0.1910 0.0760 0.00130 0.028 NA 0.012 NA 0.027 2.3e-02 NA 9.4e-02 NA 2.6e-02
6 GTEx Thyroid 0.1140 0.0380 0.00014 0.183 NA 0.145 NA 0.179 6.0e-14 NA 3.5e-11 NA 1.1e-13
7 METSIM Adipose 0.0733 0.0230 0.00001 0.037 0.033 0.038 0.036 0.030 2.9e-06 8.6e-06 1.8e-06 3.8e-06 2.1e-05
8 YFS Blood 0.0175 0.0085 0.00620 0.002 0.005 0.001 0.006 0.002 5.0e-02 6.8e-03 1.4e-01 4.0e-03 5.0e-02
9 TCGA Pheochromocytoma and Paraganglioma 0.0570 0.0340 0.00860 0.067 0.035 0.051 NA 0.056 1.2e-03 1.5e-02 4.2e-03 NA 2.9e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.2 0.3 0.9 0.1 0.2 -1.0 0.2 -0.3 -0.8 -0.3 -0.8 -0.8
Bipolar Disorder or Schizophrenia 0.8 2.0 5.0 1.8 2.2 0.4 1.9 1.8 -0.7 1.2 -0.6 0.3
Depressed Affect (Nagel 2018) 3.0 6.3 10.8 -2.0 -2.1 -3.3 -2.7 -2.7 2.2 -2.1 2.1 -3.0
Depression (Nagel 2018) 4.1 6.1 11.4 -2.7 -2.6 -2.5 -3.4 -2.8 2.0 -2.5 0.7 -2.2
Intelligence (Savage-Jansen 2018) 0.8 2.4 4.1 1.6 1.9 1.4 2.0 1.8 -1.0 1.8 -0.1 1.3
Neuroticism (Nagel 2018) 1.8 4.2 7.0 -2.0 -1.8 -2.7 -2.0 -2.2 2.1 -1.7 1.1 -2.7
Schizophrenia (2018) 1.6 3.4 7.6 2.2 2.8 1.4 2.3 2.6 -0.3 1.7 -0.1 1.0
Schizophrenia vs Biploar Disorder 1.9 2.5 4.4 1.1 1.2 2.1 2.1 1.6 -1.2 0.7 -1.8 1.7
Worry (Nagel 2018) 0.6 1.4 3.7 -1.0 -0.8 -1.6 -1.2 -0.9 0.8 -0.6 1.1 -1.9
Alzheimer’s Disease (in mother) 0.8 1.0 2.2 1.2 1.3 1.2 -0.3 0.7 -0.7 1.5 -0.6 -0.8
Alzheimer’s Disease (in father) 0.2 0.2 0.8 -0.4 0.1 0.4 0.9 0.4 0.5 0.1 -0.2 0.5
Alzheimer’s Disease (including proxy) 0.4 0.5 1.2 0.8 1.0 0.7 -0.1 0.5 -0.2 1.1 -0.5 -0.8
Crohns Disease (2017) 0.0 0.1 0.2 0.1 -0.2 0.4 0.3 0.0 0.3 -0.1 -0.3 0.4
Irritable Bowel Disease (IBD) 0.1 0.3 2.0 0.3 -0.2 -0.2 -0.3 0.2 0.4 -0.2 -0.5 1.4
Ulcerative Colitis (UC) 0.4 0.7 3.7 0.1 -0.3 -0.1 -0.8 0.2 1.0 -0.3 -0.6 1.9
Major Depression (MDD) 0.8 0.9 2.6 -1.0 -1.3 -1.0 -1.6 -1.0 -0.2 -0.5 -0.0 0.9
Reaction Time 0.5 1.0 2.5 1.6 1.3 0.4 0.9 1.5 -0.5 0.8 0.4 1.1
Verbal and Numeric Reasoning (VNR) 1.9 4.6 8.2 2.7 2.7 1.3 2.9 2.4 -2.2 1.7 0.2 1.9
Breast Cancer 0.2 0.6 2.4 -0.6 -0.3 -0.5 0.6 0.0 0.9 -1.0 1.5 -0.1
Ovarian Cancer 1.1 1.4 2.9 -1.5 -1.4 -1.7 -0.2 -1.1 0.5 -1.3 1.5 0.7
Prostate Cancer 0.5 0.8 2.6 -1.1 -0.8 0.5 0.7 -0.8 0.9 -0.5 0.2 -1.6
Age at First Birth 6.0 8.7 11.9 3.0 3.2 2.7 3.1 3.2 -2.4 3.4 -3.5 1.6
Bipolar Disorder (2011) 0.5 0.5 2.2 -0.3 -0.2 1.2 0.5 -0.3 0.6 0.0 -1.5 -0.1
Body Mass Index (BMI) (2010) 0.6 0.9 2.2 -0.2 0.4 1.3 1.5 0.6 1.1 0.3 -1.4 -0.4
Coronary Artery Disease (CAD) 1.3 1.6 3.6 1.1 0.8 1.3 1.9 1.6 -0.5 1.4 -1.3 0.7
Crohns Disease (2012) 0.4 0.7 2.1 -0.5 -0.6 -0.5 -1.1 -0.8 1.4 -0.4 -0.1 -1.0
Mean Putamen Volume 1.6 1.8 3.7 1.9 1.8 -0.3 1.0 1.9 -1.0 1.9 -0.0 0.3
Fasting Glucose 0.3 0.3 0.8 -0.8 0.0 -0.8 0.2 -0.4 0.9 -0.0 -0.9 0.2
HbA1C 0.5 0.6 2.1 0.3 0.6 1.5 0.5 0.8 -0.6 -0.2 -0.3 1.0
HDL Cholesterol 0.6 1.0 3.4 1.3 0.9 -0.3 -0.0 0.7 -1.8 1.3 -0.6 -0.0
LDL Cholesterol 2.6 4.1 8.4 -2.5 -2.9 -0.6 -2.0 -2.9 1.7 -2.3 -0.6 -0.9
Lupus 0.4 0.6 1.4 0.5 0.4 -1.1 0.1 0.7 -1.0 1.2 0.7 0.6
Neuroticism (2016) 3.7 5.3 10.0 -2.3 -2.6 -3.1 -2.0 -3.2 1.8 -2.0 1.2 -1.8
Primary Biliary Cirrhosis 0.1 0.1 0.5 0.2 -0.2 -0.7 0.1 0.2 0.2 -0.1 -0.2 0.0
Rheumatoid Arthritis 0.3 0.4 1.2 1.1 0.7 0.6 -0.4 0.3 -0.5 0.1 0.7 -0.4
Schizophrenia (2014) 1.4 3.1 6.4 2.1 2.4 1.5 2.5 2.2 -0.5 1.4 -0.7 1.0
Triglycerides 0.6 1.1 3.3 -1.6 -0.8 -0.7 -1.1 -0.5 1.8 -0.2 -0.0 -1.0
Type 2 Diabetes (T2D) (2012) 0.3 0.3 1.5 -0.2 0.4 -0.4 0.3 0.8 1.2 0.5 -0.2 -0.3
Ulcerative Colitis 0.2 0.3 1.4 0.1 -0.1 -0.6 -0.3 0.0 0.4 -0.8 -0.6 1.2
Blood Eosinophil Count 0.3 2.2 3.7 1.0 1.2 1.3 1.9 1.7 -1.1 1.0 -1.9 1.7
Blood Platelet Count 4.4 51.0 123.2 -7.4 -7.1 6.1 5.9 -0.3 8.2 -5.2 -8.0 11.1
Blood Red Count 0.2 1.6 6.9 -0.4 -0.5 -1.5 -1.3 -0.6 0.0 -0.9 1.3 -2.6
Blood White Count 0.1 0.6 2.2 0.2 -0.8 -0.3 -1.5 0.0 0.8 -1.2 -0.2 0.7
Heel T-Score 0.1 0.9 2.4 0.3 0.8 1.6 0.1 1.1 -0.3 1.5 -0.8 -0.8
BMI 0.5 2.6 7.3 -1.7 -1.4 -0.5 -0.9 -1.2 2.7 -1.4 0.2 -2.6
Height 0.4 8.5 29.7 0.8 1.3 5.5 2.8 2.4 0.5 1.9 -5.2 0.7
Waist Hip Ratio (WHR) 0.2 0.8 3.1 -0.0 0.3 1.8 -0.1 0.5 0.2 -0.3 -1.2 1.4
Systolic Blood Pressure 0.3 1.5 3.8 -1.4 -1.5 -0.8 -1.3 -1.1 1.2 -1.9 -0.1 -0.7
Smoking Status 3.1 7.3 12.7 -2.8 -3.0 -2.4 -3.6 -3.1 2.5 -2.4 1.6 -2.4
Allergy or Eczema 0.3 0.8 2.3 0.8 0.6 0.8 1.1 0.8 -0.4 -1.0 0.2 1.5
Cardiovascular Disease 0.8 2.5 4.3 -1.8 -1.7 -1.9 -1.0 -1.3 2.1 -1.9 -1.1 -1.0
Hypothyroidism (self reported) 0.7 1.6 3.6 1.2 1.7 1.9 0.5 1.5 -0.9 1.6 0.0 0.8
Respiratory disease 0.0 0.1 0.3 0.1 0.4 -0.2 0.0 -0.1 0.2 0.4 0.5 -0.5
Type 2 Diabetes (T2D) (2018) 0.7 1.3 2.5 -1.3 -1.6 -1.2 -0.6 -1.2 1.4 -0.8 1.0 -0.3
Lung FEV1/FVC ratio 0.6 3.2 5.3 -1.8 -2.2 -1.9 -1.2 -2.3 0.6 -2.2 2.3 0.1
Lung FVC 0.3 1.7 6.9 0.8 1.5 1.1 0.5 1.4 -0.9 2.6 -1.2 -0.2
Neuroticism 1.6 4.0 6.5 -2.2 -1.9 -2.5 -1.3 -2.5 1.6 -1.7 1.1 -2.5
Chronotype (morning person) 5.7 13.2 31.2 5.6 5.5 1.7 3.2 4.1 -2.8 4.3 -0.7 -0.6
Hair Pigment 0.1 1.8 10.8 0.3 -0.1 1.9 0.3 0.3 1.0 -0.2 -3.3 0.6
Tanning 0.3 3.4 8.3 2.0 2.2 0.8 1.1 1.9 -2.9 2.7 -0.7 0.9
Hand grip strength (left) 0.6 1.5 4.5 -1.4 -0.8 2.1 0.5 -0.5 1.4 -1.0 -1.7 0.7
Number of treatments/medications taken 0.8 1.5 3.5 -1.9 -1.3 -1.4 -0.6 -1.7 0.9 -1.1 0.6 -0.7
Average weekly spirits intake 0.4 0.5 2.9 0.0 0.2 0.7 0.5 0.5 -0.6 0.6 -1.7 0.2
Sensitivity / hurt feelings 0.9 1.5 2.7 -1.6 -1.4 -1.3 -0.8 -1.7 1.2 -1.2 0.2 -0.9
Frequency of depressed mood in last 2 weeks 4.2 5.9 10.2 -2.5 -1.8 -3.2 -2.7 -2.5 2.0 -2.1 1.0 -3.2
Hearing difficulty/problems: Yes 0.5 0.7 2.0 -0.2 -0.4 0.2 -1.2 -0.9 -1.4 -0.3 1.2 0.7
Relative age of first facial hair 0.2 0.3 0.9 -0.3 -0.4 0.5 -1.0 -0.3 0.6 -0.5 0.6 -0.6
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 1.8 -0.6 -0.2 -1.2 -1.2 -0.9 0.1 -0.1 -0.1 -1.3
Ever used hormone-replacement therapy (HRT) 0.9 1.2 6.1 0.8 0.0 -0.4 0.4 0.1 -1.1 -0.2 2.5 1.6
Ever had hysterectomy (womb removed) 0.9 1.1 2.5 1.0 0.5 0.1 -0.8 1.1 -1.3 1.3 -1.0 1.6
Systolic blood pressure, automated reading 0.5 1.4 3.2 -1.0 -1.2 -1.5 -0.8 -1.2 0.5 -1.8 1.2 -0.8
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.2 -0.3 0.1 -0.4 1.1 -0.3 0.0 0.4 -0.8 0.5
Angina 1.2 1.6 4.0 -0.8 -1.2 -1.9 -1.2 -1.4 -0.1 -1.1 2.0 -0.1
Medication for hormone replacement therapy 0.3 0.3 1.9 -0.3 -0.1 1.4 -0.1 0.3 0.2 0.2 0.8 -0.3
Vitamin and mineral supplements 0.0 0.0 0.1 0.0 -0.1 0.1 -0.3 0.1 -0.0 -0.1 0.0 0.4
Supplements: Zinc 1.5 1.6 2.7 -1.4 -1.4 -1.0 -1.0 -1.6 1.2 -1.6 -0.1 -1.3
Medication: Co-codamol 1.5 1.7 5.2 -0.6 -0.9 -1.9 -2.3 -1.1 -0.1 -1.3 -0.1 -1.6
Medication: Metformin 0.1 0.1 0.6 -0.5 -0.5 -0.8 0.1 -0.3 0.3 -0.2 -0.2 0.1
Diabetes (father) 0.7 0.8 1.6 1.3 1.1 0.1 1.0 1.0 -0.6 0.8 -0.7 -0.9
Diabetes (mother) 2.4 3.0 4.7 -1.8 -2.0 -1.7 -1.6 -2.1 2.0 -2.2 0.6 -0.8
Severe depression (siblings) 0.6 0.6 2.3 0.0 0.3 -1.5 -0.8 -0.3 0.7 0.7 -0.5 -1.2
Pack years adult smoking proportion 1.3 2.0 3.8 -1.4 -2.0 -1.0 -1.4 -1.6 0.8 -1.9 1.3 0.5
Impedance of leg (right) 0.4 1.9 10.2 -0.4 -1.4 1.1 -0.0 -0.8 -0.2 -1.2 -1.1 3.2
Leg fat-free mass (left) 0.3 1.6 4.7 -0.5 0.4 0.7 1.2 0.5 1.7 0.6 -1.9 -2.2
Trunk fat percentage 0.4 1.5 3.0 -1.6 -1.7 -1.2 -0.6 -1.2 1.5 -1.4 -0.2 -0.7
Hand grip strength (right) 0.6 1.7 4.5 -1.7 -1.1 0.4 -0.1 -1.1 2.1 -1.2 -1.9 -0.6
Townsend deprivation index at recruitment 1.6 2.2 4.3 -1.6 -1.5 -1.5 -2.1 -1.2 1.3 -1.1 0.4 -2.0
Current tobacco smoking 0.5 0.9 1.8 -0.8 -1.2 -1.3 -0.5 -1.3 0.2 -1.1 0.2 -0.9
Average weekly fortified wine intake 1.6 1.9 11.1 1.1 1.0 3.3 0.9 1.1 -0.9 0.5 -0.9 -0.1
Maternal smoking around birth 0.6 0.8 1.8 -0.6 -0.2 -1.4 -1.3 -0.6 1.1 -0.3 1.3 -0.5
Fed-up feelings 2.6 4.7 8.6 -2.5 -2.3 -1.9 -1.7 -2.4 1.9 -2.9 0.7 -2.4
Frequency of unenthusiasm / disinterest in last 2 weeks 1.8 2.4 4.8 -1.7 -1.2 -2.2 -1.8 -1.5 1.6 -1.1 -0.6 -1.6
Relative age voice broke 0.7 1.1 3.5 -0.7 -0.8 -0.6 -1.4 -1.1 0.7 -0.5 1.9 -0.7
Taking other prescription medications 1.9 3.0 5.1 -1.8 -1.5 -1.8 -2.2 -2.0 1.4 -1.4 1.0 -2.0
Age when periods started (menarche) 0.1 0.3 1.4 0.4 0.5 -0.4 -0.3 0.3 0.2 0.2 0.1 -1.2
Bilateral oophorectomy (both ovaries removed) 0.9 1.0 5.0 0.8 0.5 -0.3 -0.3 0.3 -2.2 0.4 1.1 1.4
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 1.3 -0.1 -0.4 1.1 -0.7 0.0 0.4 -0.7 0.4 0.1
Tinnitus: Yes, but not now, but have in the past 1.4 1.5 3.6 1.1 0.9 -0.2 1.9 1.0 -1.5 1.7 -0.7 1.2
Qualifications: CSEs or equivalent 0.4 0.5 1.9 -0.5 -0.5 -0.2 -0.4 -0.4 1.4 -0.9 0.8 -0.8
Serious illness, injury or assault to yourself 1.2 1.5 3.5 -1.1 -0.7 -1.6 -1.2 -1.5 0.1 -0.9 -1.1 -1.9
High blood pressure 0.8 2.3 3.9 -2.0 -1.9 -1.9 -1.4 -1.6 0.9 -1.9 0.1 -0.8
Hayfever, allergic rhinitis or eczema 0.3 0.6 1.4 0.3 0.2 0.6 1.2 0.3 -0.8 -1.2 0.5 1.2
Multivitamins +/- minerals 0.9 1.2 2.4 -1.5 -1.3 -0.3 -0.7 -1.5 1.1 -0.9 -0.2 -1.4
Stomach or abdominal pain in last month 0.2 0.2 0.5 0.3 0.3 -0.5 -0.4 0.6 -0.3 0.6 0.7 -0.5
Supplements: Glucosamine 0.5 0.7 1.7 0.4 0.5 -1.2 0.2 0.2 -0.1 1.2 1.3 -1.0
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 1.4 -0.0 -0.2 -0.9 -0.5 -0.2 0.1 -0.8 0.2 1.2
Medication: Atenolol 4.2 5.2 10.9 -3.0 -3.3 -0.9 -1.8 -2.9 2.2 -2.9 0.9 -0.7
Medication: Levothyroxine sodium 0.1 0.2 0.5 -0.6 -0.7 -0.2 -0.4 -0.5 0.3 -0.4 0.4 0.4
Sitting height 1.1 8.0 21.1 1.5 2.5 4.2 3.4 2.6 0.4 2.5 -4.6 0.7
Chronic bronchitis/emphysema (father) 1.2 1.4 3.4 -1.0 -1.6 -1.8 -1.0 -1.4 -0.5 -0.6 1.5 -0.4
High blood pressure (mother) 0.8 1.1 2.9 -1.0 -1.3 -1.0 -1.7 -1.4 -0.9 -0.8 -0.2 0.4
Body mass index (BMI) 0.5 2.1 4.3 -1.5 -1.5 -1.8 -1.2 -1.4 1.5 -1.1 0.7 -2.1
Impedance of leg (left) 0.4 1.9 9.1 -0.4 -1.4 1.3 -0.4 -0.7 -0.3 -1.2 -1.3 3.0
Leg predicted mass (left) 0.3 1.5 4.7 -0.5 0.4 0.7 1.1 0.5 1.7 0.7 -1.8 -2.2
Trunk fat mass 0.2 1.0 2.7 -1.4 -1.3 -0.6 -0.0 -0.8 1.6 -0.8 -0.7 -1.0
Waist circumference 0.1 0.5 0.8 -0.9 -0.9 -0.7 -0.2 -0.6 0.8 -0.8 -0.1 -0.5
Number of incorrect matches in round 0.3 0.4 2.4 0.5 0.7 0.1 0.5 0.1 -0.2 0.4 0.3 1.5
Past tobacco smoking 1.3 2.3 6.0 1.8 1.8 1.4 2.5 1.6 -1.2 1.1 -1.0 -0.1
Alcohol usually taken with meals 4.6 7.4 11.8 3.0 2.5 2.5 3.3 2.5 -2.7 2.5 -1.4 3.4
Nervous feelings 0.3 0.6 1.8 -0.3 -0.3 -1.1 -0.8 -0.7 0.5 -0.6 0.2 -1.3
Frequency of tenseness / restlessness in last 2 weeks 2.4 3.7 7.4 -2.1 -1.9 -2.7 -1.6 -2.2 1.8 -1.6 1.5 -1.7
Hearing difficulty/problems with background noise 1.1 1.8 3.3 -1.8 -1.7 -0.6 -1.5 -1.6 1.2 -1.7 0.3 -0.8
Hair/balding pattern: Pattern 2 0.4 0.5 2.2 0.6 0.1 -0.6 -0.2 0.5 -1.0 -0.6 -0.4 1.5
Had menopause 1.0 1.3 2.9 1.4 0.5 -1.6 0.2 0.5 -0.7 0.7 1.7 1.6
Had other major operations 0.5 0.6 2.2 0.9 0.3 0.4 -0.5 -0.6 -1.5 0.9 0.6 0.7
Forced vital capacity (FVC) 0.6 2.2 8.1 -0.9 0.2 2.6 1.4 0.5 1.0 0.9 -2.9 -0.5
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.2 1.0 0.3 -0.1 1.0 0.1 0.3 0.1 -0.4 -0.1 0.5
Ever unenthusiastic/disinterested for a whole week 1.0 1.2 3.3 0.8 0.9 -1.5 -0.1 1.0 -1.8 0.5 1.4 0.7
Qualifications: None of the above 3.1 6.6 14.0 -3.2 -3.7 -1.8 -2.0 -3.4 2.2 -3.1 -0.2 -1.1
Financial difficulties in last 2 years 1.7 2.3 3.0 -1.3 -1.6 -1.6 -1.4 -1.7 1.5 -1.6 1.6 -1.0
Mouth/teeth dental problems 1.4 2.2 4.4 1.7 1.7 1.7 2.1 1.7 -0.7 1.4 -0.8 0.9
Heart attack 1.2 1.5 4.2 -1.5 -1.3 -2.0 -0.4 -1.2 0.6 -1.4 1.1 -0.5
Allergy 0.4 0.9 3.0 -0.7 -0.6 -0.6 -1.7 -0.5 1.1 0.6 -0.7 -1.0
Pain all over the body in last month 0.6 0.6 1.4 0.8 0.1 -1.1 -0.6 0.6 -0.4 1.2 0.3 1.2
Diabetes (self-reported) 0.4 0.6 2.0 -0.5 -1.0 -1.4 -0.6 -0.6 0.1 -0.4 0.9 -0.3
Hayfever/allergic rhinitis (self-reported) 0.8 1.1 2.5 1.1 1.3 0.1 1.4 1.6 -0.3 0.7 0.8 1.0
Medication: Ramipril 0.3 0.4 1.0 0.2 -0.5 -0.9 -0.7 -0.6 -0.0 0.5 -0.4 -1.0
Medication: Simvastatin 2.7 4.0 12.2 -1.6 -2.2 -3.5 -2.3 -2.3 0.4 -1.7 1.7 0.6
Fluid intelligence score 1.4 2.9 6.1 2.5 2.3 -0.0 2.1 1.8 -1.8 1.4 1.4 0.6
Illnesses of siblings 0.4 0.6 1.0 0.7 0.9 0.2 0.6 0.7 -0.9 1.0 1.0 -0.4
Neuroticism score 2.4 5.0 7.9 -2.6 -2.1 -2.2 -1.6 -2.6 2.0 -2.4 1.2 -2.8
Weight 0.2 0.8 2.2 -1.0 -0.7 0.0 0.3 -0.4 1.5 -0.3 -1.2 -1.4
Impedance of arm (right) 0.3 1.3 2.6 -1.6 -1.5 0.2 -0.6 -1.3 1.2 -1.4 -0.6 1.2
Arm fat percentage (right) 0.5 2.1 3.9 -1.9 -1.7 -1.2 -1.0 -1.6 2.0 -1.2 0.2 -1.4
Trunk fat-free mass 0.4 2.5 7.0 0.3 1.1 2.3 1.5 1.2 1.2 1.4 -2.6 -1.4
Hip circumference 0.2 1.0 1.9 -1.3 -1.4 -1.4 0.2 -1.1 0.6 -1.0 0.1 -1.1
Time employed in main current job 0.5 0.6 1.3 -1.0 -0.6 0.7 0.1 -0.2 0.8 -0.6 -1.1 1.1
Alcohol intake versus 10 years previously 1.6 2.3 4.0 -1.5 -1.7 -0.8 -1.9 -1.7 1.6 -1.6 -0.1 -2.0
Father’s age at death 4.3 5.7 9.9 3.1 2.9 1.6 3.0 2.8 -1.9 2.6 -0.2 1.9
Worrier / anxious feelings 0.2 0.4 1.6 -0.5 0.2 -1.1 -0.7 0.3 0.3 -0.1 -0.2 -1.3
Frequency of tiredness / lethargy in last 2 weeks 1.3 2.1 4.1 -1.8 -1.3 -2.0 -1.0 -1.8 1.3 -1.2 0.8 -1.3
Falls in the last year 0.4 0.6 1.2 -1.0 -0.9 0.2 -0.7 -0.6 1.1 -0.5 -0.5 -0.8
Hair/balding pattern: Pattern 3 0.8 1.2 2.8 0.5 1.0 1.5 1.5 0.5 -1.2 1.7 0.1 -0.6
Number of live births 0.9 1.3 2.3 -0.9 -1.2 -1.4 0.5 -1.0 1.4 -1.5 -0.9 1.0
Forced expiratory volume in 1-second (FEV1) 0.5 1.7 5.0 -1.6 -0.6 2.0 0.4 -0.4 1.6 0.0 -2.2 -0.5
Pulse rate 0.2 0.3 0.6 0.0 0.6 0.4 0.8 0.3 -0.1 0.8 -0.5 -0.6
Happiness 2.9 3.5 12.0 -1.6 -1.5 -1.7 -1.7 -1.9 1.8 -1.7 -0.1 -3.5
Noisy workplace 0.6 0.8 4.0 -0.6 -0.3 -0.5 -0.3 -0.8 0.3 -0.3 -1.3 -2.0
Qualifications: A levels/AS levels or equivalent 0.4 1.0 2.4 0.9 1.5 0.8 0.9 1.2 -0.5 1.5 0.0 -0.1
Serious illness, injury or assault of a close relative in last 2 years 2.0 2.3 4.6 1.3 2.1 1.1 2.0 1.8 -1.1 1.7 -0.3 1.2
Mouth/teeth dental problems: Dentures 0.5 0.9 2.6 -0.5 -1.0 -1.6 -1.2 -0.5 -0.2 -0.2 1.6 0.5
Asthma 0.7 1.3 3.1 1.5 1.8 -0.7 0.9 1.2 -0.2 1.2 1.6 -0.3
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 1.8 -1.1 -1.3 0.6 0.2 -1.3 0.7 -0.6 -0.4 -0.5
Medication: Cholesterol lowering 0.2 0.3 0.5 -0.7 -0.6 -0.7 -0.3 -0.5 0.6 -0.5 -0.1 0.6
Depression (self-reported) 3.3 3.9 5.9 -2.4 -2.0 -2.1 -2.0 -2.3 1.3 -2.0 1.4 -2.0
Medication: Lansoprazole 0.7 0.8 1.5 -0.9 -1.1 -0.3 -0.9 -1.0 -0.4 -0.9 1.2 1.0
Prospective memory result 0.9 1.1 4.6 1.2 1.3 -0.2 0.7 1.1 -2.1 0.5 0.1 0.3
Lung cancer (father) 2.1 2.5 5.4 -1.7 -1.4 -2.3 -1.7 -1.5 0.6 -1.4 1.6 -1.4
Illnesses of mother 1.7 2.0 4.8 1.4 1.4 0.9 2.2 1.9 0.4 1.7 -1.0 1.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.4 4.2 -0.6 0.5 1.8 1.0 0.3 1.2 1.1 -2.0 -0.9
Pulse wave Arterial Stiffness index 0.1 0.2 0.4 0.2 0.3 -0.6 -0.3 0.6 -0.3 0.2 0.4 -0.4
Impedance of arm (left) 0.2 0.9 2.8 -1.0 -1.1 0.2 0.2 -1.0 0.3 -1.2 -0.3 1.7
Arm fat mass (right) 0.3 1.4 3.3 -1.4 -1.2 -0.9 -0.6 -1.1 1.8 -0.9 -0.2 -1.6
Trunk predicted mass 0.4 2.5 6.6 0.3 1.1 2.3 1.5 1.2 1.1 1.4 -2.6 -1.5
Standing height 0.7 6.9 20.7 0.8 1.5 4.3 3.2 1.9 0.3 1.9 -4.5 1.1
Length of working week for main job 3.2 3.5 5.7 -2.1 -2.2 -1.3 -2.1 -2.4 1.5 -2.0 0.7 -1.9
Exposure to tobacco smoke at home 1.0 1.1 2.6 -1.5 -1.5 -0.6 -1.6 -1.0 0.7 -0.7 -0.4 0.7
Breastfed as a baby 1.9 2.4 5.0 1.7 0.9 1.6 1.1 1.2 -2.2 0.8 -1.9 1.9
Tense / ‘highly strung’ 0.8 1.3 2.7 -1.4 -1.3 -0.8 -1.7 -1.2 1.2 -0.6 0.9 -1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.4 0.6 2.6 -0.1 -0.3 -0.8 -0.6 -0.5 0.6 -0.2 1.6 -0.9
Hair/balding pattern: Pattern 4 0.1 0.2 0.8 0.4 0.9 -0.2 0.3 0.6 0.1 0.4 0.1 -0.5
Birth weight of first child 0.1 0.2 1.2 -0.5 -0.1 0.6 -0.4 -0.0 0.3 0.2 -0.1 -1.1
Peak expiratory flow (PEF) 0.7 1.7 4.3 -2.1 -1.6 1.0 -0.3 -1.2 1.8 -0.9 -0.8 -1.2
Pulse wave reflection index 0.2 0.3 0.5 0.3 0.3 -0.7 -0.6 0.6 -0.5 -0.3 0.7 -0.4
Ever highly irritable/argumentative for 2 days 0.5 0.6 1.9 -1.4 -0.7 0.1 -1.0 -0.4 0.1 -0.8 -0.8 -0.2
Loud music exposure frequency 0.6 0.6 1.8 -1.3 -0.7 -0.3 -1.4 -0.6 0.5 -0.8 -0.3 0.6
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 3.3 -0.2 0.0 -0.4 -0.3 -0.4 0.2 -0.9 0.6 -1.8
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 3.4 -1.8 -1.2 0.1 -0.3 -1.2 1.0 -1.3 -1.7 -0.6
Blood clot in the leg (DVT) 0.4 0.5 1.2 -0.4 -0.6 -0.7 0.2 -0.9 -0.3 -0.8 0.9 -1.1
Medication: Paracetamol 0.3 0.6 2.6 0.0 0.2 1.6 0.9 0.3 0.1 0.9 -0.4 0.7
Headache pain in last month 0.7 1.2 2.4 -1.0 -1.4 -1.1 -1.1 -1.6 0.9 -0.8 0.2 -1.3
Medication for cholesterol, blood pressure or diabetes 0.5 0.8 1.5 1.2 1.2 0.5 0.9 1.1 -1.0 0.9 0.6 -0.0
Glaucoma (self-reported) 0.6 0.7 1.6 -0.8 -0.9 -0.1 -1.2 -1.1 1.3 -0.6 -0.1 -0.4
Gout (self-reported) 0.3 0.4 1.4 -1.2 -0.7 1.1 -0.6 -0.2 0.6 0.3 -0.2 -0.1
Hypothyroidism/myxoedema (self-reported) 0.0 0.1 0.3 0.0 0.4 0.6 0.3 0.4 0.2 0.1 0.3 -0.1
Medication: Amlodipine 0.5 0.8 1.7 -1.1 -0.9 -0.6 -1.3 -0.9 -0.1 -0.7 -0.8 -0.8
Medication: Ventolin 100micrograms inhaler 0.7 0.9 2.8 -0.9 -0.3 -0.6 -1.1 -0.4 1.4 -0.9 0.6 -1.7
Birth weight 1.6 3.6 5.6 2.4 2.1 0.5 2.1 2.2 -1.9 1.9 -1.3 1.8
Chronic bronchitis/emphysema (mother) 5.3 6.2 8.8 -3.0 -2.2 -2.3 -2.0 -2.7 2.9 -2.4 2.6 -2.1
High blood pressure (siblings) 1.3 1.9 4.4 -1.5 -2.1 -0.3 -1.6 -1.6 1.1 -1.7 -0.9 0.1
Forced vital capacity (FVC), Best measure 0.7 2.6 7.1 -0.0 1.1 2.4 1.8 1.2 0.6 1.9 -2.7 -0.8
Body fat percentage 0.4 1.6 3.1 -1.5 -1.8 -1.5 -0.7 -1.3 1.5 -1.3 0.1 -0.8
Leg fat percentage (right) 0.5 2.0 4.0 -1.4 -2.0 -1.5 -1.2 -1.4 1.7 -1.4 0.8 -0.6
Arm fat-free mass (right) 0.3 1.5 4.5 0.5 0.7 1.1 1.5 1.0 0.8 1.1 -2.1 -1.5
Exposure to tobacco smoke outside home 0.3 0.5 2.4 0.2 -0.0 -0.7 0.0 0.3 -0.2 -0.8 1.6 -0.7
Comparative body size at age 10 0.9 2.4 8.7 -1.7 -1.9 -2.9 -0.7 -2.2 0.5 -0.4 0.5 0.3
Number of full brothers 1.5 1.9 4.3 -2.1 -1.6 1.0 -0.6 -1.5 1.8 -1.4 -1.3 -0.2
Worry too long after embarrassment 0.5 0.8 2.1 -1.1 -0.7 -1.0 0.0 -0.6 1.5 -0.5 -0.8 -0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.9 1.1 4.3 0.5 0.3 -1.9 -0.8 -0.3 0.7 -0.3 2.1 -0.5
Wheeze or whistling in the chest in last year 0.2 0.4 1.7 0.6 0.3 -0.0 -0.1 0.0 -1.3 0.7 0.8 0.2
Number of children fathered 0.7 0.8 1.5 -0.8 -1.2 1.2 -0.3 -1.1 0.3 -0.9 -0.8 0.8
Reason for reducing amount of alcohol drunk: Health precaution 0.4 0.4 1.9 0.3 0.4 -0.1 0.0 0.7 -1.4 0.5 0.1 1.1
Age at first live birth 1.7 3.1 5.9 1.6 2.4 1.9 1.3 2.1 -0.6 1.9 -2.4 -0.3
Pulse wave peak to peak time 0.2 0.2 0.7 -0.2 -0.4 0.8 0.4 -0.6 0.4 -0.2 -0.5 0.4
Health satisfaction 1.2 1.5 3.4 -1.0 -1.1 -1.8 -1.3 -1.3 -0.5 -0.6 1.1 -1.8
Shortness of breath walking on level ground 0.3 0.4 1.5 0.4 0.3 1.2 0.6 0.3 -0.3 0.9 -0.3 0.6
Qualifications: College or University degree 1.5 4.8 8.5 2.8 2.9 1.1 1.5 2.8 -2.6 2.9 -0.6 0.8
Eye problems/disorders: None of the above 0.8 1.0 2.1 1.2 1.4 -0.1 0.3 1.5 -1.1 1.2 -0.3 0.5
Mouth/teeth dental problems: Loose teeth 2.2 2.6 7.5 -1.6 -2.1 0.4 -2.7 -2.0 0.2 -1.6 -0.3 -1.3
Emphysema/chronic bronchitis 1.3 1.4 3.2 -1.5 -1.7 0.4 -1.6 -1.8 0.8 -0.5 0.2 -1.0
Medication for pain relief, constipation, heartburn 0.6 0.9 2.4 1.4 1.3 0.5 0.4 1.6 -0.8 0.5 -1.0 -0.5
Neck or shoulder pain in last month 2.0 2.8 5.7 -2.1 -2.4 -0.5 -1.9 -2.2 1.6 -1.9 0.2 -0.2
Medication: Blood pressure 0.2 0.4 1.0 -0.7 -0.7 -1.0 -0.5 -0.5 0.6 -0.8 0.2 -0.1
Angina (self-reported) 1.0 1.3 3.3 -0.7 -1.2 -1.6 -1.1 -1.4 -0.2 -1.0 1.8 0.0
Migraine (self-reported) 1.3 1.6 3.1 1.5 1.7 -0.6 0.4 1.1 -1.6 1.8 0.9 0.8
Medication: Ibuprofen 1.7 2.1 5.3 -2.3 -2.1 0.2 -0.3 -2.2 1.0 -1.4 -0.4 -0.7
Medication: Allopurinol 0.3 0.4 1.3 0.1 0.0 0.4 -0.1 0.3 -1.1 0.9 0.6 1.0
Medication: Omeprazole 3.4 4.0 7.4 -2.7 -2.3 -1.4 -2.5 -2.2 2.6 -1.3 0.3 -1.5
Medication: Seretide 50 evohaler 0.9 1.0 2.7 -0.6 -1.0 -0.3 -0.1 -1.2 1.7 -0.9 0.3 -1.5
Mean time to correctly identify matches 1.2 2.3 4.7 2.2 1.9 -0.2 1.1 2.0 -1.1 1.4 1.2 1.6
Heart disease (mother) 0.2 0.2 1.1 0.2 0.3 0.5 0.0 0.6 0.2 -0.2 1.0 0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.1 1.3 3.0 -1.3 -1.7 -0.5 -1.6 -1.6 0.1 -1.1 0.3 0.6
Whole body fat mass 0.3 1.4 2.9 -1.5 -1.5 -0.9 -0.2 -1.1 1.7 -1.0 -0.4 -1.4
Leg fat mass (right) 0.4 1.6 3.8 -1.6 -1.7 -1.0 -0.4 -1.2 2.0 -1.1 -0.3 -1.3
Arm predicted mass (right) 0.4 2.0 4.9 0.7 1.0 1.5 1.8 1.3 0.8 1.3 -2.2 -1.3
Pulse rate, automated reading 0.1 0.2 0.7 0.2 0.8 -0.2 0.1 0.3 0.1 0.8 -0.0 -0.1
Alcohol intake frequency. 1.0 2.3 3.3 -0.8 -1.7 -1.8 -1.6 -1.7 0.9 -1.8 1.2 -1.6
Comparative height size at age 10 0.8 4.6 12.1 0.8 1.9 3.5 2.8 1.8 -0.9 1.7 -2.9 1.2
Number of full sisters 0.3 0.4 1.0 0.9 0.6 0.6 0.2 0.3 -1.0 -0.2 0.1 0.8
Suffer from ‘nerves’ 3.2 5.1 10.2 -2.2 -1.9 -2.6 -3.2 -2.1 1.8 -1.9 1.7 -2.4
Overall health rating 4.7 10.0 15.9 -3.0 -3.8 -3.6 -4.0 -3.8 1.8 -3.3 2.0 -2.2
Chest pain or discomfort 0.3 0.5 3.8 -0.1 0.2 -0.5 -0.2 0.1 -0.2 0.3 2.0 0.2
Had major operations 0.6 0.7 1.8 0.1 0.8 1.3 0.1 0.2 -0.3 0.9 -1.1 -1.4
Age at last live birth 2.6 3.8 8.3 2.2 2.9 1.5 2.1 2.6 -1.1 2.0 -1.3 0.8
Family relationship satisfaction 0.3 0.3 1.6 -0.1 0.6 0.5 -0.3 0.2 0.2 0.5 -0.6 -1.3
Leg pain on walking 0.5 0.7 1.9 -0.8 -0.8 0.4 -0.2 -1.0 1.4 -1.2 -0.4 0.0
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 1.3 0.4 0.9 1.0 0.7 1.0 0.5 1.1 -0.4 -0.1
Commuting to job workplace: Car/motor vehicle 0.4 0.4 2.2 -0.0 -0.3 -1.5 0.4 -0.6 -0.2 0.4 -0.9 -0.4
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 0.7 0.8 0.3 0.5 0.3 0.5 -0.4 0.1 0.7 0.1
Medication: Aspirin 0.5 0.7 1.8 -0.7 -0.9 -1.3 -0.5 -1.4 -0.7 -0.8 0.2 0.5
Supplements: Vitamin C 0.3 0.3 1.8 -0.2 -0.3 0.1 1.3 -0.4 0.5 -0.8 0.0 -0.3
Knee pain experienced in last month 1.0 1.6 9.8 -0.4 -0.9 -3.1 -1.6 -0.5 0.4 -0.8 0.2 0.3
Hypertension (Self-reported) 0.7 1.9 3.3 -1.8 -1.7 -1.7 -1.3 -1.6 0.8 -1.8 -0.3 -0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.3 1.7 -0.4 -0.2 0.3 0.4 0.1 0.8 0.4 0.3 1.3
Illnesses of father: Heart disease 0.9 1.2 2.9 -1.7 -1.1 -0.8 -0.3 -0.8 1.4 -1.2 -0.6 -1.4
Illnesses of siblings: Diabetes 1.3 1.6 4.6 1.2 1.3 0.6 2.1 1.3 -1.1 1.3 -1.0 1.0
Smoking status: Previous 1.8 2.7 6.5 -1.9 -2.1 -1.0 -2.6 -1.9 1.5 -1.3 1.2 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 1.3 2.7 8.4 0.5 0.8 2.9 2.3 1.1 0.7 1.1 -2.5 0.7
Whole body fat-free mass 0.4 2.1 5.5 0.1 0.9 1.7 1.4 1.0 1.4 1.2 -2.3 -1.9
Leg fat-free mass (right) 0.3 1.6 5.5 -0.5 0.5 0.7 1.0 0.6 1.6 0.7 -1.8 -2.4
Arm fat percentage (left) 0.4 1.8 3.1 -1.7 -1.6 -1.3 -0.6 -1.4 1.8 -1.2 0.3 -1.3
Average weekly red wine intake 2.1 3.0 5.6 2.1 1.9 0.9 1.7 1.9 -2.3 2.4 -0.1 1.1
Handedness (chirality/laterality): Left-handed 2.3 2.8 5.3 -2.3 -1.9 -0.6 -1.0 -2.2 2.2 -2.2 -0.1 -0.2
Mood swings 1.9 3.4 6.2 -1.0 -1.2 -2.5 -2.2 -1.8 0.8 -1.9 2.5 -1.9
Loneliness, isolation 0.4 0.6 2.2 -0.2 -0.4 -0.9 -0.4 -0.8 1.5 -0.6 -0.1 -1.1
Long-standing illness, disability or infirmity 0.4 0.6 2.3 0.7 0.4 -1.5 -0.3 0.2 -0.3 0.6 1.0 1.1
Ever had bowel cancer screening 0.4 0.5 1.3 0.8 0.9 -0.8 -0.1 0.4 -0.9 0.5 1.2 -0.2
Diabetes diagnosed by doctor 0.4 0.6 2.4 -0.4 -0.8 -1.6 -0.5 -0.6 0.2 -0.1 1.2 -0.1
Ever had stillbirth, spontaneous miscarriage or termination 1.7 1.9 7.1 -1.3 -0.9 2.3 0.4 -0.0 2.7 -0.7 -1.1 0.2
Friendships satisfaction 0.1 0.2 0.5 -0.3 0.2 0.2 0.4 -0.3 0.5 -0.3 0.5 -0.7
Qualifications: nursing, teaching 1.6 2.5 5.6 1.5 1.4 0.7 1.3 1.6 -2.2 2.4 -1.3 1.2
Commuting to job workplace: Walk 0.7 0.8 3.1 0.5 0.9 0.2 0.8 0.9 -0.6 0.7 0.9 1.8
Eye problems/disorders: Cataract 0.4 0.4 0.9 -0.8 -0.9 0.9 -0.3 -0.6 0.4 -0.8 0.5 -0.1
Mouth/teeth dental problems: Mouth ulcers 1.3 2.0 7.2 -0.2 -0.2 -2.0 -2.0 -1.0 0.1 -0.8 2.7 -1.0
Medication for cholesterol 0.1 0.2 0.5 0.4 0.6 -0.4 -0.2 0.7 0.6 -0.4 0.3 0.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 0.9 -0.7 -0.6 -0.9 -0.9 -0.4 0.7 -0.4 0.4 -0.8
Back pain experienced in last month 0.5 0.7 3.6 0.1 0.3 -1.9 -0.1 0.1 -0.4 1.3 0.9 -0.1
Mineral and other dietary supplements 0.5 0.7 2.2 0.4 0.6 1.2 0.4 1.2 -0.2 0.3 -1.5 0.6
Breast cancer (self-reported) 0.9 1.0 2.7 -0.8 -1.0 -1.6 -1.5 -1.1 1.2 -0.3 -0.1 -0.1
Asthma (self-reported) 0.7 1.4 3.1 1.5 1.8 -0.6 1.1 1.2 -0.4 1.1 1.7 -0.1
Osteoporosis (self-reported) 0.8 0.9 2.1 -0.4 -0.8 -1.4 -0.7 -1.5 -1.2 -0.9 0.8 0.2
Osteoarthritis (self-reported) 0.2 0.2 1.2 -0.1 -0.5 -0.1 -0.4 -0.3 0.4 0.4 1.1 -0.3
Medication: Aspirin 0.8 1.0 2.6 -1.0 -1.1 -1.4 -0.8 -1.6 -0.4 -1.2 0.1 0.1
Medication: Gliclazide 0.6 0.7 1.4 -1.2 -0.7 -1.0 -0.0 -0.9 0.8 -0.2 1.2 -0.8
Illnesses of father: None of the above (group 1) 0.5 0.7 1.4 -0.7 -0.7 0.6 -0.7 -0.6 1.2 -1.2 -0.9 -0.6
Smoking status: Current 0.5 0.9 2.3 -0.9 -1.1 -1.5 -0.7 -1.2 0.3 -0.9 0.2 -0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 1.9 -1.0 -0.1 -0.3 0.7 0.1 1.4 0.1 0.9 -0.9
Whole body water mass 0.4 2.0 5.1 0.2 1.0 1.6 1.4 1.0 1.2 1.2 -2.2 -1.8
Leg predicted mass (right) 0.3 1.6 5.6 -0.5 0.5 0.8 1.0 0.5 1.7 0.7 -1.8 -2.4
Arm fat mass (left) 0.3 1.3 2.8 -1.5 -1.3 -0.8 -0.3 -1.1 1.7 -0.9 -0.3 -1.6
Number of self-reported non-cancer illnesses 1.0 1.7 6.2 -1.0 -0.9 -2.5 -1.0 -1.1 1.1 -1.3 1.2 -0.7
Average weekly champagne plus white wine intake 0.1 0.1 0.3 0.5 -0.2 0.0 0.5 0.1 0.2 0.1 -0.6 -0.1
Miserableness 4.1 7.0 11.7 -2.8 -2.3 -2.4 -2.5 -2.6 2.8 -3.2 1.5 -3.4
Guilty feelings 1.0 1.5 2.9 -1.6 -1.1 -0.6 -0.0 -1.5 1.7 -1.6 -0.4 -1.2
Wears glasses or contact lenses 1.1 1.2 2.2 1.3 1.1 1.1 0.6 1.1 -1.3 1.2 0.5 1.5
Ever taken oral contraceptive pill 0.4 0.5 1.7 -0.4 -0.4 1.0 0.4 -0.1 1.3 -0.0 0.9 0.5
Hearing aid user 0.3 0.3 1.1 0.5 0.1 0.7 -1.0 0.1 -0.2 0.4 0.8 0.1
Mother’s age at death 0.0 0.1 0.2 0.1 0.3 -0.1 -0.2 0.1 -0.5 0.2 0.1 -0.1
Financial situation satisfaction 0.9 1.2 4.6 -1.1 -0.4 -0.1 0.1 -0.4 1.6 -0.2 -1.3 -2.1
Tinnitus: Yes, now most or all of the time 0.4 0.5 1.0 -0.8 -0.5 -0.5 -1.0 -0.4 0.5 -0.4 0.9 -0.9
Commuting to job workplace: Public transport 0.2 0.3 0.8 0.1 -0.2 0.4 -0.9 -0.7 0.4 -0.5 0.8 -0.2
Eye problems/disorders: Glaucoma 0.3 0.4 1.2 -0.3 -0.6 1.1 -0.2 -0.4 1.0 -0.6 -0.5 -0.3
Medication: Blood pressure 0.5 0.9 2.7 -0.9 -1.2 -0.6 -1.1 -1.6 -0.7 -0.6 -0.2 -0.6
Pain type(s) experienced in last month: Hip pain 0.5 0.6 1.7 -0.5 -0.2 -1.2 0.7 0.0 0.8 0.6 -0.5 -1.3
Supplements: Fish oil (including cod liver oil) 0.3 0.4 1.2 -0.7 -0.7 -0.3 0.0 -1.1 0.8 -0.2 0.8 -0.2
High cholesterol (Self-reported) 0.5 0.9 3.4 -0.9 -1.2 -1.8 -0.2 -1.4 0.4 -0.6 0.2 0.0
Medication: Bendroflumethiazide 0.9 1.4 2.8 1.7 1.7 -0.9 0.9 1.0 -1.5 0.9 0.9 0.1
Medication: Paracetamol 0.2 0.4 1.7 -0.6 -0.3 1.3 0.5 -0.4 -0.4 0.0 -0.4 0.7
Medication: Lisinopril 0.4 0.5 1.1 0.7 0.7 -0.6 1.0 1.0 -0.7 0.2 -0.5 0.5
Medication: Atorvastatin 0.1 0.2 0.4 -0.2 -0.1 -0.7 0.5 -0.0 -0.2 0.3 0.6 -0.5
Illnesses of father: High blood pressure 0.2 0.2 0.7 0.5 0.1 -0.8 0.1 0.1 -0.3 0.6 -0.7 -0.1
Alcohol drinker status: Never 0.8 0.9 3.8 0.1 -0.2 -1.9 -0.8 -0.5 0.1 -0.4 0.9 -1.6
Ever smoked 0.3 0.5 1.1 -0.8 -0.8 -0.3 -1.1 -0.6 0.7 -0.6 -0.5 0.5
Basal metabolic rate 0.3 1.7 4.8 -0.2 0.5 1.4 1.1 0.7 1.5 0.8 -2.2 -1.8
Leg fat percentage (left) 0.6 2.0 3.7 -1.5 -1.9 -1.4 -1.4 -1.4 1.8 -1.3 0.7 -0.9
Arm fat-free mass (left) 0.3 1.6 4.1 0.3 0.8 1.5 1.0 0.9 1.3 1.1 -2.0 -1.8
Number of operations (self-reported) 1.2 1.7 5.3 -0.7 -0.9 -0.8 -0.9 -1.8 -0.4 -0.8 2.3 -1.9
Average weekly beer plus cider intake 0.3 0.5 1.9 -0.6 -0.3 -0.9 -1.0 0.0 1.4 -0.1 0.7 -0.2
Irritability 0.5 0.8 3.7 -1.2 -0.2 0.4 -0.6 -0.7 0.4 -0.5 -0.5 -1.9
Risk taking 0.2 0.2 1.1 0.2 0.3 -0.4 -0.0 0.5 -0.4 -0.2 1.0 0.5
Ever had prostate specific antigen (PSA) test 0.7 0.8 4.4 0.5 0.2 0.8 0.6 0.5 -0.9 0.5 -2.1 0.8
Fractured/broken bones in last 5 years 0.8 1.0 3.7 -0.4 -0.3 -1.9 -0.9 -0.5 0.6 -0.5 1.4 -1.2
Age started oral contraceptive pill 3.9 4.9 10.8 3.3 2.7 -0.0 1.7 2.1 -3.1 2.7 1.0 1.0
Diastolic blood pressure, automated reading 1.5 4.6 7.7 -2.7 -2.3 -1.8 -0.4 -2.5 2.8 -2.5 1.0 -2.0
Ever depressed for a whole week 0.9 1.2 4.9 0.6 1.0 -2.2 -0.3 0.8 -1.5 0.6 0.8 -0.3
Unable to work because of sickness or disability 1.3 1.6 9.1 -0.3 -0.9 -3.0 -0.2 -1.3 -0.9 -1.1 0.7 0.6
Commuting to job workplace: Cycle 1.0 1.3 2.7 1.0 1.3 1.0 0.9 1.4 -0.7 1.3 0.2 1.6
Myopia 3.2 4.7 8.6 2.8 2.9 0.6 2.0 2.9 -2.1 2.5 0.0 1.4
Vascular/heart problems diagnosed by doctor 1.3 3.5 6.2 2.5 2.3 2.5 1.8 2.0 -1.1 2.1 -0.3 0.9
Cholesterol lowering medication 1.8 2.6 7.1 -0.6 -1.7 -2.7 -1.1 -1.9 -1.7 -0.5 2.1 1.0
Medication: Omeprazole (e.g. Zanprol) 2.4 2.9 5.5 -2.4 -1.8 -1.3 -2.2 -2.0 2.0 -1.2 0.4 -1.1
Pain experienced in last month 0.8 1.3 9.7 0.3 0.3 3.1 0.7 0.1 -1.0 -0.6 -0.0 -0.1
Supplements: Calcium 0.8 0.9 2.1 -0.7 -0.1 -1.4 0.0 -0.8 -0.7 -0.9 1.4 -1.3
Basal cell carcinoma (self-reported) 0.8 0.9 2.0 -1.1 -1.4 -0.1 -0.8 -1.4 0.4 -1.3 -0.4 -0.1
Heart attack/myocardial infarction (self-reported) 1.2 1.5 4.6 -1.4 -1.2 -2.1 -0.5 -1.2 0.5 -1.3 1.3 -0.3
Deep venous thrombosis (DVT) (self-reported) 0.6 0.7 1.8 -0.7 -0.9 -0.8 -0.1 -1.1 -0.1 -0.8 0.8 -1.4
Heart disease (siblings) 3.2 3.9 14.1 -1.6 -1.9 -2.1 -3.8 -1.8 1.4 -2.0 0.7 -0.9
Alcohol drinker status: Previous 0.9 1.0 2.1 1.2 0.6 -0.7 0.6 0.7 -1.5 1.4 1.0 0.7
Pack years of smoking 1.4 2.0 4.1 -1.4 -2.0 -0.8 -1.6 -1.7 0.9 -1.8 1.3 0.5
Impedance of whole body 0.3 1.4 5.3 -0.9 -1.6 0.4 -0.5 -1.1 -0.0 -1.6 -0.5 2.3
Leg fat mass (left) 0.4 1.7 4.0 -1.6 -1.6 -1.1 -0.5 -1.2 2.0 -1.1 -0.3 -1.5
Arm predicted mass (left) 0.3 1.4 3.5 0.3 0.6 1.3 0.9 0.7 1.2 0.9 -1.9 -1.8