Hub : Genes

RASL10B

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1030	0.0360	0.00015	0.036	NA	0.043	NA	0.039	5.5e-04	NA	1.8e-04	NA	3.5e-04
2	GTEx	Adipose Visceral Omentum	0.1080	0.0450	0.00460	0.046	NA	0.000	NA	0.021	2.0e-03	NA	3.1e-01	NA	2.7e-02
3	GTEx	Adrenal Gland	0.1833	0.0818	0.00410	-0.007	NA	0.002	NA	-0.001	6.7e-01	NA	2.8e-01	NA	3.6e-01
4	GTEx	Muscle Skeletal	0.0505	0.0196	0.00066	0.042	NA	0.061	NA	0.052	5.8e-05	NA	1.2e-06	NA	7.5e-06
5	GTEx	Pancreas	0.1910	0.0760	0.00130	0.028	NA	0.012	NA	0.027	2.3e-02	NA	9.4e-02	NA	2.6e-02
6	GTEx	Thyroid	0.1140	0.0380	0.00014	0.183	NA	0.145	NA	0.179	6.0e-14	NA	3.5e-11	NA	1.1e-13
7	METSIM	Adipose	0.0733	0.0230	0.00001	0.037	0.033	0.038	0.036	0.030	2.9e-06	8.6e-06	1.8e-06	3.8e-06	2.1e-05
8	YFS	Blood	0.0175	0.0085	0.00620	0.002	0.005	0.001	0.006	0.002	5.0e-02	6.8e-03	1.4e-01	4.0e-03	5.0e-02
9	TCGA	Pheochromocytoma and Paraganglioma	0.0570	0.0340	0.00860	0.067	0.035	0.051	NA	0.056	1.2e-03	1.5e-02	4.2e-03	NA	2.9e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.2	0.3	0.9	0.1	0.2	-1.0	0.2	-0.3	-0.8	-0.3	-0.8	-0.8
Bipolar Disorder or Schizophrenia	0.8	2.0	5.0	1.8	2.2	0.4	1.9	1.8	-0.7	1.2	-0.6	0.3
Depressed Affect (Nagel 2018)	3.0	6.3	10.8	-2.0	-2.1	-3.3	-2.7	-2.7	2.2	-2.1	2.1	-3.0
Depression (Nagel 2018)	4.1	6.1	11.4	-2.7	-2.6	-2.5	-3.4	-2.8	2.0	-2.5	0.7	-2.2
Intelligence (Savage-Jansen 2018)	0.8	2.4	4.1	1.6	1.9	1.4	2.0	1.8	-1.0	1.8	-0.1	1.3
Neuroticism (Nagel 2018)	1.8	4.2	7.0	-2.0	-1.8	-2.7	-2.0	-2.2	2.1	-1.7	1.1	-2.7
Schizophrenia (2018)	1.6	3.4	7.6	2.2	2.8	1.4	2.3	2.6	-0.3	1.7	-0.1	1.0
Schizophrenia vs Biploar Disorder	1.9	2.5	4.4	1.1	1.2	2.1	2.1	1.6	-1.2	0.7	-1.8	1.7
Worry (Nagel 2018)	0.6	1.4	3.7	-1.0	-0.8	-1.6	-1.2	-0.9	0.8	-0.6	1.1	-1.9
Alzheimer’s Disease (in mother)	0.8	1.0	2.2	1.2	1.3	1.2	-0.3	0.7	-0.7	1.5	-0.6	-0.8
Alzheimer’s Disease (in father)	0.2	0.2	0.8	-0.4	0.1	0.4	0.9	0.4	0.5	0.1	-0.2	0.5
Alzheimer’s Disease (including proxy)	0.4	0.5	1.2	0.8	1.0	0.7	-0.1	0.5	-0.2	1.1	-0.5	-0.8
Crohns Disease (2017)	0.0	0.1	0.2	0.1	-0.2	0.4	0.3	0.0	0.3	-0.1	-0.3	0.4
Irritable Bowel Disease (IBD)	0.1	0.3	2.0	0.3	-0.2	-0.2	-0.3	0.2	0.4	-0.2	-0.5	1.4
Ulcerative Colitis (UC)	0.4	0.7	3.7	0.1	-0.3	-0.1	-0.8	0.2	1.0	-0.3	-0.6	1.9
Major Depression (MDD)	0.8	0.9	2.6	-1.0	-1.3	-1.0	-1.6	-1.0	-0.2	-0.5	-0.0	0.9
Reaction Time	0.5	1.0	2.5	1.6	1.3	0.4	0.9	1.5	-0.5	0.8	0.4	1.1
Verbal and Numeric Reasoning (VNR)	1.9	4.6	8.2	2.7	2.7	1.3	2.9	2.4	-2.2	1.7	0.2	1.9
Breast Cancer	0.2	0.6	2.4	-0.6	-0.3	-0.5	0.6	0.0	0.9	-1.0	1.5	-0.1
Ovarian Cancer	1.1	1.4	2.9	-1.5	-1.4	-1.7	-0.2	-1.1	0.5	-1.3	1.5	0.7
Prostate Cancer	0.5	0.8	2.6	-1.1	-0.8	0.5	0.7	-0.8	0.9	-0.5	0.2	-1.6
Age at First Birth	6.0	8.7	11.9	3.0	3.2	2.7	3.1	3.2	-2.4	3.4	-3.5	1.6
Bipolar Disorder (2011)	0.5	0.5	2.2	-0.3	-0.2	1.2	0.5	-0.3	0.6	0.0	-1.5	-0.1
Body Mass Index (BMI) (2010)	0.6	0.9	2.2	-0.2	0.4	1.3	1.5	0.6	1.1	0.3	-1.4	-0.4
Coronary Artery Disease (CAD)	1.3	1.6	3.6	1.1	0.8	1.3	1.9	1.6	-0.5	1.4	-1.3	0.7
Crohns Disease (2012)	0.4	0.7	2.1	-0.5	-0.6	-0.5	-1.1	-0.8	1.4	-0.4	-0.1	-1.0
Mean Putamen Volume	1.6	1.8	3.7	1.9	1.8	-0.3	1.0	1.9	-1.0	1.9	-0.0	0.3
Fasting Glucose	0.3	0.3	0.8	-0.8	0.0	-0.8	0.2	-0.4	0.9	-0.0	-0.9	0.2
HbA1C	0.5	0.6	2.1	0.3	0.6	1.5	0.5	0.8	-0.6	-0.2	-0.3	1.0
HDL Cholesterol	0.6	1.0	3.4	1.3	0.9	-0.3	-0.0	0.7	-1.8	1.3	-0.6	-0.0
LDL Cholesterol	2.6	4.1	8.4	-2.5	-2.9	-0.6	-2.0	-2.9	1.7	-2.3	-0.6	-0.9
Lupus	0.4	0.6	1.4	0.5	0.4	-1.1	0.1	0.7	-1.0	1.2	0.7	0.6
Neuroticism (2016)	3.7	5.3	10.0	-2.3	-2.6	-3.1	-2.0	-3.2	1.8	-2.0	1.2	-1.8
Primary Biliary Cirrhosis	0.1	0.1	0.5	0.2	-0.2	-0.7	0.1	0.2	0.2	-0.1	-0.2	0.0
Rheumatoid Arthritis	0.3	0.4	1.2	1.1	0.7	0.6	-0.4	0.3	-0.5	0.1	0.7	-0.4
Schizophrenia (2014)	1.4	3.1	6.4	2.1	2.4	1.5	2.5	2.2	-0.5	1.4	-0.7	1.0
Triglycerides	0.6	1.1	3.3	-1.6	-0.8	-0.7	-1.1	-0.5	1.8	-0.2	-0.0	-1.0
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.5	-0.2	0.4	-0.4	0.3	0.8	1.2	0.5	-0.2	-0.3
Ulcerative Colitis	0.2	0.3	1.4	0.1	-0.1	-0.6	-0.3	0.0	0.4	-0.8	-0.6	1.2
Blood Eosinophil Count	0.3	2.2	3.7	1.0	1.2	1.3	1.9	1.7	-1.1	1.0	-1.9	1.7
Blood Platelet Count	4.4	51.0	123.2	-7.4	-7.1	6.1	5.9	-0.3	8.2	-5.2	-8.0	11.1
Blood Red Count	0.2	1.6	6.9	-0.4	-0.5	-1.5	-1.3	-0.6	0.0	-0.9	1.3	-2.6
Blood White Count	0.1	0.6	2.2	0.2	-0.8	-0.3	-1.5	0.0	0.8	-1.2	-0.2	0.7
Heel T-Score	0.1	0.9	2.4	0.3	0.8	1.6	0.1	1.1	-0.3	1.5	-0.8	-0.8
BMI	0.5	2.6	7.3	-1.7	-1.4	-0.5	-0.9	-1.2	2.7	-1.4	0.2	-2.6
Height	0.4	8.5	29.7	0.8	1.3	5.5	2.8	2.4	0.5	1.9	-5.2	0.7
Waist Hip Ratio (WHR)	0.2	0.8	3.1	-0.0	0.3	1.8	-0.1	0.5	0.2	-0.3	-1.2	1.4
Systolic Blood Pressure	0.3	1.5	3.8	-1.4	-1.5	-0.8	-1.3	-1.1	1.2	-1.9	-0.1	-0.7
Smoking Status	3.1	7.3	12.7	-2.8	-3.0	-2.4	-3.6	-3.1	2.5	-2.4	1.6	-2.4
Allergy or Eczema	0.3	0.8	2.3	0.8	0.6	0.8	1.1	0.8	-0.4	-1.0	0.2	1.5
Cardiovascular Disease	0.8	2.5	4.3	-1.8	-1.7	-1.9	-1.0	-1.3	2.1	-1.9	-1.1	-1.0
Hypothyroidism (self reported)	0.7	1.6	3.6	1.2	1.7	1.9	0.5	1.5	-0.9	1.6	0.0	0.8
Respiratory disease	0.0	0.1	0.3	0.1	0.4	-0.2	0.0	-0.1	0.2	0.4	0.5	-0.5
Type 2 Diabetes (T2D) (2018)	0.7	1.3	2.5	-1.3	-1.6	-1.2	-0.6	-1.2	1.4	-0.8	1.0	-0.3
Lung FEV1/FVC ratio	0.6	3.2	5.3	-1.8	-2.2	-1.9	-1.2	-2.3	0.6	-2.2	2.3	0.1
Lung FVC	0.3	1.7	6.9	0.8	1.5	1.1	0.5	1.4	-0.9	2.6	-1.2	-0.2
Neuroticism	1.6	4.0	6.5	-2.2	-1.9	-2.5	-1.3	-2.5	1.6	-1.7	1.1	-2.5
Chronotype (morning person)	5.7	13.2	31.2	5.6	5.5	1.7	3.2	4.1	-2.8	4.3	-0.7	-0.6
Hair Pigment	0.1	1.8	10.8	0.3	-0.1	1.9	0.3	0.3	1.0	-0.2	-3.3	0.6
Tanning	0.3	3.4	8.3	2.0	2.2	0.8	1.1	1.9	-2.9	2.7	-0.7	0.9
Hand grip strength (left)	0.6	1.5	4.5	-1.4	-0.8	2.1	0.5	-0.5	1.4	-1.0	-1.7	0.7
Number of treatments/medications taken	0.8	1.5	3.5	-1.9	-1.3	-1.4	-0.6	-1.7	0.9	-1.1	0.6	-0.7
Average weekly spirits intake	0.4	0.5	2.9	0.0	0.2	0.7	0.5	0.5	-0.6	0.6	-1.7	0.2
Sensitivity / hurt feelings	0.9	1.5	2.7	-1.6	-1.4	-1.3	-0.8	-1.7	1.2	-1.2	0.2	-0.9
Frequency of depressed mood in last 2 weeks	4.2	5.9	10.2	-2.5	-1.8	-3.2	-2.7	-2.5	2.0	-2.1	1.0	-3.2
Hearing difficulty/problems: Yes	0.5	0.7	2.0	-0.2	-0.4	0.2	-1.2	-0.9	-1.4	-0.3	1.2	0.7
Relative age of first facial hair	0.2	0.3	0.9	-0.3	-0.4	0.5	-1.0	-0.3	0.6	-0.5	0.6	-0.6
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.8	-0.6	-0.2	-1.2	-1.2	-0.9	0.1	-0.1	-0.1	-1.3
Ever used hormone-replacement therapy (HRT)	0.9	1.2	6.1	0.8	0.0	-0.4	0.4	0.1	-1.1	-0.2	2.5	1.6
Ever had hysterectomy (womb removed)	0.9	1.1	2.5	1.0	0.5	0.1	-0.8	1.1	-1.3	1.3	-1.0	1.6
Systolic blood pressure, automated reading	0.5	1.4	3.2	-1.0	-1.2	-1.5	-0.8	-1.2	0.5	-1.8	1.2	-0.8
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.2	-0.3	0.1	-0.4	1.1	-0.3	0.0	0.4	-0.8	0.5
Angina	1.2	1.6	4.0	-0.8	-1.2	-1.9	-1.2	-1.4	-0.1	-1.1	2.0	-0.1
Medication for hormone replacement therapy	0.3	0.3	1.9	-0.3	-0.1	1.4	-0.1	0.3	0.2	0.2	0.8	-0.3
Vitamin and mineral supplements	0.0	0.0	0.1	0.0	-0.1	0.1	-0.3	0.1	-0.0	-0.1	0.0	0.4
Supplements: Zinc	1.5	1.6	2.7	-1.4	-1.4	-1.0	-1.0	-1.6	1.2	-1.6	-0.1	-1.3
Medication: Co-codamol	1.5	1.7	5.2	-0.6	-0.9	-1.9	-2.3	-1.1	-0.1	-1.3	-0.1	-1.6
Medication: Metformin	0.1	0.1	0.6	-0.5	-0.5	-0.8	0.1	-0.3	0.3	-0.2	-0.2	0.1
Diabetes (father)	0.7	0.8	1.6	1.3	1.1	0.1	1.0	1.0	-0.6	0.8	-0.7	-0.9
Diabetes (mother)	2.4	3.0	4.7	-1.8	-2.0	-1.7	-1.6	-2.1	2.0	-2.2	0.6	-0.8
Severe depression (siblings)	0.6	0.6	2.3	0.0	0.3	-1.5	-0.8	-0.3	0.7	0.7	-0.5	-1.2
Pack years adult smoking proportion	1.3	2.0	3.8	-1.4	-2.0	-1.0	-1.4	-1.6	0.8	-1.9	1.3	0.5
Impedance of leg (right)	0.4	1.9	10.2	-0.4	-1.4	1.1	-0.0	-0.8	-0.2	-1.2	-1.1	3.2
Leg fat-free mass (left)	0.3	1.6	4.7	-0.5	0.4	0.7	1.2	0.5	1.7	0.6	-1.9	-2.2
Trunk fat percentage	0.4	1.5	3.0	-1.6	-1.7	-1.2	-0.6	-1.2	1.5	-1.4	-0.2	-0.7
Hand grip strength (right)	0.6	1.7	4.5	-1.7	-1.1	0.4	-0.1	-1.1	2.1	-1.2	-1.9	-0.6
Townsend deprivation index at recruitment	1.6	2.2	4.3	-1.6	-1.5	-1.5	-2.1	-1.2	1.3	-1.1	0.4	-2.0
Current tobacco smoking	0.5	0.9	1.8	-0.8	-1.2	-1.3	-0.5	-1.3	0.2	-1.1	0.2	-0.9
Average weekly fortified wine intake	1.6	1.9	11.1	1.1	1.0	3.3	0.9	1.1	-0.9	0.5	-0.9	-0.1
Maternal smoking around birth	0.6	0.8	1.8	-0.6	-0.2	-1.4	-1.3	-0.6	1.1	-0.3	1.3	-0.5
Fed-up feelings	2.6	4.7	8.6	-2.5	-2.3	-1.9	-1.7	-2.4	1.9	-2.9	0.7	-2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.8	2.4	4.8	-1.7	-1.2	-2.2	-1.8	-1.5	1.6	-1.1	-0.6	-1.6
Relative age voice broke	0.7	1.1	3.5	-0.7	-0.8	-0.6	-1.4	-1.1	0.7	-0.5	1.9	-0.7
Taking other prescription medications	1.9	3.0	5.1	-1.8	-1.5	-1.8	-2.2	-2.0	1.4	-1.4	1.0	-2.0
Age when periods started (menarche)	0.1	0.3	1.4	0.4	0.5	-0.4	-0.3	0.3	0.2	0.2	0.1	-1.2
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	5.0	0.8	0.5	-0.3	-0.3	0.3	-2.2	0.4	1.1	1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.3	-0.1	-0.4	1.1	-0.7	0.0	0.4	-0.7	0.4	0.1
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	3.6	1.1	0.9	-0.2	1.9	1.0	-1.5	1.7	-0.7	1.2
Qualifications: CSEs or equivalent	0.4	0.5	1.9	-0.5	-0.5	-0.2	-0.4	-0.4	1.4	-0.9	0.8	-0.8
Serious illness, injury or assault to yourself	1.2	1.5	3.5	-1.1	-0.7	-1.6	-1.2	-1.5	0.1	-0.9	-1.1	-1.9
High blood pressure	0.8	2.3	3.9	-2.0	-1.9	-1.9	-1.4	-1.6	0.9	-1.9	0.1	-0.8
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.4	0.3	0.2	0.6	1.2	0.3	-0.8	-1.2	0.5	1.2
Multivitamins +/- minerals	0.9	1.2	2.4	-1.5	-1.3	-0.3	-0.7	-1.5	1.1	-0.9	-0.2	-1.4
Stomach or abdominal pain in last month	0.2	0.2	0.5	0.3	0.3	-0.5	-0.4	0.6	-0.3	0.6	0.7	-0.5
Supplements: Glucosamine	0.5	0.7	1.7	0.4	0.5	-1.2	0.2	0.2	-0.1	1.2	1.3	-1.0
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.4	-0.0	-0.2	-0.9	-0.5	-0.2	0.1	-0.8	0.2	1.2
Medication: Atenolol	4.2	5.2	10.9	-3.0	-3.3	-0.9	-1.8	-2.9	2.2	-2.9	0.9	-0.7
Medication: Levothyroxine sodium	0.1	0.2	0.5	-0.6	-0.7	-0.2	-0.4	-0.5	0.3	-0.4	0.4	0.4
Sitting height	1.1	8.0	21.1	1.5	2.5	4.2	3.4	2.6	0.4	2.5	-4.6	0.7
Chronic bronchitis/emphysema (father)	1.2	1.4	3.4	-1.0	-1.6	-1.8	-1.0	-1.4	-0.5	-0.6	1.5	-0.4
High blood pressure (mother)	0.8	1.1	2.9	-1.0	-1.3	-1.0	-1.7	-1.4	-0.9	-0.8	-0.2	0.4
Body mass index (BMI)	0.5	2.1	4.3	-1.5	-1.5	-1.8	-1.2	-1.4	1.5	-1.1	0.7	-2.1
Impedance of leg (left)	0.4	1.9	9.1	-0.4	-1.4	1.3	-0.4	-0.7	-0.3	-1.2	-1.3	3.0
Leg predicted mass (left)	0.3	1.5	4.7	-0.5	0.4	0.7	1.1	0.5	1.7	0.7	-1.8	-2.2
Trunk fat mass	0.2	1.0	2.7	-1.4	-1.3	-0.6	-0.0	-0.8	1.6	-0.8	-0.7	-1.0
Waist circumference	0.1	0.5	0.8	-0.9	-0.9	-0.7	-0.2	-0.6	0.8	-0.8	-0.1	-0.5
Number of incorrect matches in round	0.3	0.4	2.4	0.5	0.7	0.1	0.5	0.1	-0.2	0.4	0.3	1.5
Past tobacco smoking	1.3	2.3	6.0	1.8	1.8	1.4	2.5	1.6	-1.2	1.1	-1.0	-0.1
Alcohol usually taken with meals	4.6	7.4	11.8	3.0	2.5	2.5	3.3	2.5	-2.7	2.5	-1.4	3.4
Nervous feelings	0.3	0.6	1.8	-0.3	-0.3	-1.1	-0.8	-0.7	0.5	-0.6	0.2	-1.3
Frequency of tenseness / restlessness in last 2 weeks	2.4	3.7	7.4	-2.1	-1.9	-2.7	-1.6	-2.2	1.8	-1.6	1.5	-1.7
Hearing difficulty/problems with background noise	1.1	1.8	3.3	-1.8	-1.7	-0.6	-1.5	-1.6	1.2	-1.7	0.3	-0.8
Hair/balding pattern: Pattern 2	0.4	0.5	2.2	0.6	0.1	-0.6	-0.2	0.5	-1.0	-0.6	-0.4	1.5
Had menopause	1.0	1.3	2.9	1.4	0.5	-1.6	0.2	0.5	-0.7	0.7	1.7	1.6
Had other major operations	0.5	0.6	2.2	0.9	0.3	0.4	-0.5	-0.6	-1.5	0.9	0.6	0.7
Forced vital capacity (FVC)	0.6	2.2	8.1	-0.9	0.2	2.6	1.4	0.5	1.0	0.9	-2.9	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	1.0	0.3	-0.1	1.0	0.1	0.3	0.1	-0.4	-0.1	0.5
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	3.3	0.8	0.9	-1.5	-0.1	1.0	-1.8	0.5	1.4	0.7
Qualifications: None of the above	3.1	6.6	14.0	-3.2	-3.7	-1.8	-2.0	-3.4	2.2	-3.1	-0.2	-1.1
Financial difficulties in last 2 years	1.7	2.3	3.0	-1.3	-1.6	-1.6	-1.4	-1.7	1.5	-1.6	1.6	-1.0
Mouth/teeth dental problems	1.4	2.2	4.4	1.7	1.7	1.7	2.1	1.7	-0.7	1.4	-0.8	0.9
Heart attack	1.2	1.5	4.2	-1.5	-1.3	-2.0	-0.4	-1.2	0.6	-1.4	1.1	-0.5
Allergy	0.4	0.9	3.0	-0.7	-0.6	-0.6	-1.7	-0.5	1.1	0.6	-0.7	-1.0
Pain all over the body in last month	0.6	0.6	1.4	0.8	0.1	-1.1	-0.6	0.6	-0.4	1.2	0.3	1.2
Diabetes (self-reported)	0.4	0.6	2.0	-0.5	-1.0	-1.4	-0.6	-0.6	0.1	-0.4	0.9	-0.3
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	2.5	1.1	1.3	0.1	1.4	1.6	-0.3	0.7	0.8	1.0
Medication: Ramipril	0.3	0.4	1.0	0.2	-0.5	-0.9	-0.7	-0.6	-0.0	0.5	-0.4	-1.0
Medication: Simvastatin	2.7	4.0	12.2	-1.6	-2.2	-3.5	-2.3	-2.3	0.4	-1.7	1.7	0.6
Fluid intelligence score	1.4	2.9	6.1	2.5	2.3	-0.0	2.1	1.8	-1.8	1.4	1.4	0.6
Illnesses of siblings	0.4	0.6	1.0	0.7	0.9	0.2	0.6	0.7	-0.9	1.0	1.0	-0.4
Neuroticism score	2.4	5.0	7.9	-2.6	-2.1	-2.2	-1.6	-2.6	2.0	-2.4	1.2	-2.8
Weight	0.2	0.8	2.2	-1.0	-0.7	0.0	0.3	-0.4	1.5	-0.3	-1.2	-1.4
Impedance of arm (right)	0.3	1.3	2.6	-1.6	-1.5	0.2	-0.6	-1.3	1.2	-1.4	-0.6	1.2
Arm fat percentage (right)	0.5	2.1	3.9	-1.9	-1.7	-1.2	-1.0	-1.6	2.0	-1.2	0.2	-1.4
Trunk fat-free mass	0.4	2.5	7.0	0.3	1.1	2.3	1.5	1.2	1.2	1.4	-2.6	-1.4
Hip circumference	0.2	1.0	1.9	-1.3	-1.4	-1.4	0.2	-1.1	0.6	-1.0	0.1	-1.1
Time employed in main current job	0.5	0.6	1.3	-1.0	-0.6	0.7	0.1	-0.2	0.8	-0.6	-1.1	1.1
Alcohol intake versus 10 years previously	1.6	2.3	4.0	-1.5	-1.7	-0.8	-1.9	-1.7	1.6	-1.6	-0.1	-2.0
Father’s age at death	4.3	5.7	9.9	3.1	2.9	1.6	3.0	2.8	-1.9	2.6	-0.2	1.9
Worrier / anxious feelings	0.2	0.4	1.6	-0.5	0.2	-1.1	-0.7	0.3	0.3	-0.1	-0.2	-1.3
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	4.1	-1.8	-1.3	-2.0	-1.0	-1.8	1.3	-1.2	0.8	-1.3
Falls in the last year	0.4	0.6	1.2	-1.0	-0.9	0.2	-0.7	-0.6	1.1	-0.5	-0.5	-0.8
Hair/balding pattern: Pattern 3	0.8	1.2	2.8	0.5	1.0	1.5	1.5	0.5	-1.2	1.7	0.1	-0.6
Number of live births	0.9	1.3	2.3	-0.9	-1.2	-1.4	0.5	-1.0	1.4	-1.5	-0.9	1.0
Forced expiratory volume in 1-second (FEV1)	0.5	1.7	5.0	-1.6	-0.6	2.0	0.4	-0.4	1.6	0.0	-2.2	-0.5
Pulse rate	0.2	0.3	0.6	0.0	0.6	0.4	0.8	0.3	-0.1	0.8	-0.5	-0.6
Happiness	2.9	3.5	12.0	-1.6	-1.5	-1.7	-1.7	-1.9	1.8	-1.7	-0.1	-3.5
Noisy workplace	0.6	0.8	4.0	-0.6	-0.3	-0.5	-0.3	-0.8	0.3	-0.3	-1.3	-2.0
Qualifications: A levels/AS levels or equivalent	0.4	1.0	2.4	0.9	1.5	0.8	0.9	1.2	-0.5	1.5	0.0	-0.1
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	4.6	1.3	2.1	1.1	2.0	1.8	-1.1	1.7	-0.3	1.2
Mouth/teeth dental problems: Dentures	0.5	0.9	2.6	-0.5	-1.0	-1.6	-1.2	-0.5	-0.2	-0.2	1.6	0.5
Asthma	0.7	1.3	3.1	1.5	1.8	-0.7	0.9	1.2	-0.2	1.2	1.6	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.8	-1.1	-1.3	0.6	0.2	-1.3	0.7	-0.6	-0.4	-0.5
Medication: Cholesterol lowering	0.2	0.3	0.5	-0.7	-0.6	-0.7	-0.3	-0.5	0.6	-0.5	-0.1	0.6
Depression (self-reported)	3.3	3.9	5.9	-2.4	-2.0	-2.1	-2.0	-2.3	1.3	-2.0	1.4	-2.0
Medication: Lansoprazole	0.7	0.8	1.5	-0.9	-1.1	-0.3	-0.9	-1.0	-0.4	-0.9	1.2	1.0
Prospective memory result	0.9	1.1	4.6	1.2	1.3	-0.2	0.7	1.1	-2.1	0.5	0.1	0.3
Lung cancer (father)	2.1	2.5	5.4	-1.7	-1.4	-2.3	-1.7	-1.5	0.6	-1.4	1.6	-1.4
Illnesses of mother	1.7	2.0	4.8	1.4	1.4	0.9	2.2	1.9	0.4	1.7	-1.0	1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	4.2	-0.6	0.5	1.8	1.0	0.3	1.2	1.1	-2.0	-0.9
Pulse wave Arterial Stiffness index	0.1	0.2	0.4	0.2	0.3	-0.6	-0.3	0.6	-0.3	0.2	0.4	-0.4
Impedance of arm (left)	0.2	0.9	2.8	-1.0	-1.1	0.2	0.2	-1.0	0.3	-1.2	-0.3	1.7
Arm fat mass (right)	0.3	1.4	3.3	-1.4	-1.2	-0.9	-0.6	-1.1	1.8	-0.9	-0.2	-1.6
Trunk predicted mass	0.4	2.5	6.6	0.3	1.1	2.3	1.5	1.2	1.1	1.4	-2.6	-1.5
Standing height	0.7	6.9	20.7	0.8	1.5	4.3	3.2	1.9	0.3	1.9	-4.5	1.1
Length of working week for main job	3.2	3.5	5.7	-2.1	-2.2	-1.3	-2.1	-2.4	1.5	-2.0	0.7	-1.9
Exposure to tobacco smoke at home	1.0	1.1	2.6	-1.5	-1.5	-0.6	-1.6	-1.0	0.7	-0.7	-0.4	0.7
Breastfed as a baby	1.9	2.4	5.0	1.7	0.9	1.6	1.1	1.2	-2.2	0.8	-1.9	1.9
Tense / ‘highly strung’	0.8	1.3	2.7	-1.4	-1.3	-0.8	-1.7	-1.2	1.2	-0.6	0.9	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.6	-0.1	-0.3	-0.8	-0.6	-0.5	0.6	-0.2	1.6	-0.9
Hair/balding pattern: Pattern 4	0.1	0.2	0.8	0.4	0.9	-0.2	0.3	0.6	0.1	0.4	0.1	-0.5
Birth weight of first child	0.1	0.2	1.2	-0.5	-0.1	0.6	-0.4	-0.0	0.3	0.2	-0.1	-1.1
Peak expiratory flow (PEF)	0.7	1.7	4.3	-2.1	-1.6	1.0	-0.3	-1.2	1.8	-0.9	-0.8	-1.2
Pulse wave reflection index	0.2	0.3	0.5	0.3	0.3	-0.7	-0.6	0.6	-0.5	-0.3	0.7	-0.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.9	-1.4	-0.7	0.1	-1.0	-0.4	0.1	-0.8	-0.8	-0.2
Loud music exposure frequency	0.6	0.6	1.8	-1.3	-0.7	-0.3	-1.4	-0.6	0.5	-0.8	-0.3	0.6
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	3.3	-0.2	0.0	-0.4	-0.3	-0.4	0.2	-0.9	0.6	-1.8
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	3.4	-1.8	-1.2	0.1	-0.3	-1.2	1.0	-1.3	-1.7	-0.6
Blood clot in the leg (DVT)	0.4	0.5	1.2	-0.4	-0.6	-0.7	0.2	-0.9	-0.3	-0.8	0.9	-1.1
Medication: Paracetamol	0.3	0.6	2.6	0.0	0.2	1.6	0.9	0.3	0.1	0.9	-0.4	0.7
Headache pain in last month	0.7	1.2	2.4	-1.0	-1.4	-1.1	-1.1	-1.6	0.9	-0.8	0.2	-1.3
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	1.5	1.2	1.2	0.5	0.9	1.1	-1.0	0.9	0.6	-0.0
Glaucoma (self-reported)	0.6	0.7	1.6	-0.8	-0.9	-0.1	-1.2	-1.1	1.3	-0.6	-0.1	-0.4
Gout (self-reported)	0.3	0.4	1.4	-1.2	-0.7	1.1	-0.6	-0.2	0.6	0.3	-0.2	-0.1
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.3	0.0	0.4	0.6	0.3	0.4	0.2	0.1	0.3	-0.1
Medication: Amlodipine	0.5	0.8	1.7	-1.1	-0.9	-0.6	-1.3	-0.9	-0.1	-0.7	-0.8	-0.8
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.8	-0.9	-0.3	-0.6	-1.1	-0.4	1.4	-0.9	0.6	-1.7
Birth weight	1.6	3.6	5.6	2.4	2.1	0.5	2.1	2.2	-1.9	1.9	-1.3	1.8
Chronic bronchitis/emphysema (mother)	5.3	6.2	8.8	-3.0	-2.2	-2.3	-2.0	-2.7	2.9	-2.4	2.6	-2.1
High blood pressure (siblings)	1.3	1.9	4.4	-1.5	-2.1	-0.3	-1.6	-1.6	1.1	-1.7	-0.9	0.1
Forced vital capacity (FVC), Best measure	0.7	2.6	7.1	-0.0	1.1	2.4	1.8	1.2	0.6	1.9	-2.7	-0.8
Body fat percentage	0.4	1.6	3.1	-1.5	-1.8	-1.5	-0.7	-1.3	1.5	-1.3	0.1	-0.8
Leg fat percentage (right)	0.5	2.0	4.0	-1.4	-2.0	-1.5	-1.2	-1.4	1.7	-1.4	0.8	-0.6
Arm fat-free mass (right)	0.3	1.5	4.5	0.5	0.7	1.1	1.5	1.0	0.8	1.1	-2.1	-1.5
Exposure to tobacco smoke outside home	0.3	0.5	2.4	0.2	-0.0	-0.7	0.0	0.3	-0.2	-0.8	1.6	-0.7
Comparative body size at age 10	0.9	2.4	8.7	-1.7	-1.9	-2.9	-0.7	-2.2	0.5	-0.4	0.5	0.3
Number of full brothers	1.5	1.9	4.3	-2.1	-1.6	1.0	-0.6	-1.5	1.8	-1.4	-1.3	-0.2
Worry too long after embarrassment	0.5	0.8	2.1	-1.1	-0.7	-1.0	0.0	-0.6	1.5	-0.5	-0.8	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.1	4.3	0.5	0.3	-1.9	-0.8	-0.3	0.7	-0.3	2.1	-0.5
Wheeze or whistling in the chest in last year	0.2	0.4	1.7	0.6	0.3	-0.0	-0.1	0.0	-1.3	0.7	0.8	0.2
Number of children fathered	0.7	0.8	1.5	-0.8	-1.2	1.2	-0.3	-1.1	0.3	-0.9	-0.8	0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.9	0.3	0.4	-0.1	0.0	0.7	-1.4	0.5	0.1	1.1
Age at first live birth	1.7	3.1	5.9	1.6	2.4	1.9	1.3	2.1	-0.6	1.9	-2.4	-0.3
Pulse wave peak to peak time	0.2	0.2	0.7	-0.2	-0.4	0.8	0.4	-0.6	0.4	-0.2	-0.5	0.4
Health satisfaction	1.2	1.5	3.4	-1.0	-1.1	-1.8	-1.3	-1.3	-0.5	-0.6	1.1	-1.8
Shortness of breath walking on level ground	0.3	0.4	1.5	0.4	0.3	1.2	0.6	0.3	-0.3	0.9	-0.3	0.6
Qualifications: College or University degree	1.5	4.8	8.5	2.8	2.9	1.1	1.5	2.8	-2.6	2.9	-0.6	0.8
Eye problems/disorders: None of the above	0.8	1.0	2.1	1.2	1.4	-0.1	0.3	1.5	-1.1	1.2	-0.3	0.5
Mouth/teeth dental problems: Loose teeth	2.2	2.6	7.5	-1.6	-2.1	0.4	-2.7	-2.0	0.2	-1.6	-0.3	-1.3
Emphysema/chronic bronchitis	1.3	1.4	3.2	-1.5	-1.7	0.4	-1.6	-1.8	0.8	-0.5	0.2	-1.0
Medication for pain relief, constipation, heartburn	0.6	0.9	2.4	1.4	1.3	0.5	0.4	1.6	-0.8	0.5	-1.0	-0.5
Neck or shoulder pain in last month	2.0	2.8	5.7	-2.1	-2.4	-0.5	-1.9	-2.2	1.6	-1.9	0.2	-0.2
Medication: Blood pressure	0.2	0.4	1.0	-0.7	-0.7	-1.0	-0.5	-0.5	0.6	-0.8	0.2	-0.1
Angina (self-reported)	1.0	1.3	3.3	-0.7	-1.2	-1.6	-1.1	-1.4	-0.2	-1.0	1.8	0.0
Migraine (self-reported)	1.3	1.6	3.1	1.5	1.7	-0.6	0.4	1.1	-1.6	1.8	0.9	0.8
Medication: Ibuprofen	1.7	2.1	5.3	-2.3	-2.1	0.2	-0.3	-2.2	1.0	-1.4	-0.4	-0.7
Medication: Allopurinol	0.3	0.4	1.3	0.1	0.0	0.4	-0.1	0.3	-1.1	0.9	0.6	1.0
Medication: Omeprazole	3.4	4.0	7.4	-2.7	-2.3	-1.4	-2.5	-2.2	2.6	-1.3	0.3	-1.5
Medication: Seretide 50 evohaler	0.9	1.0	2.7	-0.6	-1.0	-0.3	-0.1	-1.2	1.7	-0.9	0.3	-1.5
Mean time to correctly identify matches	1.2	2.3	4.7	2.2	1.9	-0.2	1.1	2.0	-1.1	1.4	1.2	1.6
Heart disease (mother)	0.2	0.2	1.1	0.2	0.3	0.5	0.0	0.6	0.2	-0.2	1.0	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.0	-1.3	-1.7	-0.5	-1.6	-1.6	0.1	-1.1	0.3	0.6
Whole body fat mass	0.3	1.4	2.9	-1.5	-1.5	-0.9	-0.2	-1.1	1.7	-1.0	-0.4	-1.4
Leg fat mass (right)	0.4	1.6	3.8	-1.6	-1.7	-1.0	-0.4	-1.2	2.0	-1.1	-0.3	-1.3
Arm predicted mass (right)	0.4	2.0	4.9	0.7	1.0	1.5	1.8	1.3	0.8	1.3	-2.2	-1.3
Pulse rate, automated reading	0.1	0.2	0.7	0.2	0.8	-0.2	0.1	0.3	0.1	0.8	-0.0	-0.1
Alcohol intake frequency.	1.0	2.3	3.3	-0.8	-1.7	-1.8	-1.6	-1.7	0.9	-1.8	1.2	-1.6
Comparative height size at age 10	0.8	4.6	12.1	0.8	1.9	3.5	2.8	1.8	-0.9	1.7	-2.9	1.2
Number of full sisters	0.3	0.4	1.0	0.9	0.6	0.6	0.2	0.3	-1.0	-0.2	0.1	0.8
Suffer from ‘nerves’	3.2	5.1	10.2	-2.2	-1.9	-2.6	-3.2	-2.1	1.8	-1.9	1.7	-2.4
Overall health rating	4.7	10.0	15.9	-3.0	-3.8	-3.6	-4.0	-3.8	1.8	-3.3	2.0	-2.2
Chest pain or discomfort	0.3	0.5	3.8	-0.1	0.2	-0.5	-0.2	0.1	-0.2	0.3	2.0	0.2
Had major operations	0.6	0.7	1.8	0.1	0.8	1.3	0.1	0.2	-0.3	0.9	-1.1	-1.4
Age at last live birth	2.6	3.8	8.3	2.2	2.9	1.5	2.1	2.6	-1.1	2.0	-1.3	0.8
Family relationship satisfaction	0.3	0.3	1.6	-0.1	0.6	0.5	-0.3	0.2	0.2	0.5	-0.6	-1.3
Leg pain on walking	0.5	0.7	1.9	-0.8	-0.8	0.4	-0.2	-1.0	1.4	-1.2	-0.4	0.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	1.3	0.4	0.9	1.0	0.7	1.0	0.5	1.1	-0.4	-0.1
Commuting to job workplace: Car/motor vehicle	0.4	0.4	2.2	-0.0	-0.3	-1.5	0.4	-0.6	-0.2	0.4	-0.9	-0.4
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.7	0.8	0.3	0.5	0.3	0.5	-0.4	0.1	0.7	0.1
Medication: Aspirin	0.5	0.7	1.8	-0.7	-0.9	-1.3	-0.5	-1.4	-0.7	-0.8	0.2	0.5
Supplements: Vitamin C	0.3	0.3	1.8	-0.2	-0.3	0.1	1.3	-0.4	0.5	-0.8	0.0	-0.3
Knee pain experienced in last month	1.0	1.6	9.8	-0.4	-0.9	-3.1	-1.6	-0.5	0.4	-0.8	0.2	0.3
Hypertension (Self-reported)	0.7	1.9	3.3	-1.8	-1.7	-1.7	-1.3	-1.6	0.8	-1.8	-0.3	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.7	-0.4	-0.2	0.3	0.4	0.1	0.8	0.4	0.3	1.3
Illnesses of father: Heart disease	0.9	1.2	2.9	-1.7	-1.1	-0.8	-0.3	-0.8	1.4	-1.2	-0.6	-1.4
Illnesses of siblings: Diabetes	1.3	1.6	4.6	1.2	1.3	0.6	2.1	1.3	-1.1	1.3	-1.0	1.0
Smoking status: Previous	1.8	2.7	6.5	-1.9	-2.1	-1.0	-2.6	-1.9	1.5	-1.3	1.2	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.7	8.4	0.5	0.8	2.9	2.3	1.1	0.7	1.1	-2.5	0.7
Whole body fat-free mass	0.4	2.1	5.5	0.1	0.9	1.7	1.4	1.0	1.4	1.2	-2.3	-1.9
Leg fat-free mass (right)	0.3	1.6	5.5	-0.5	0.5	0.7	1.0	0.6	1.6	0.7	-1.8	-2.4
Arm fat percentage (left)	0.4	1.8	3.1	-1.7	-1.6	-1.3	-0.6	-1.4	1.8	-1.2	0.3	-1.3
Average weekly red wine intake	2.1	3.0	5.6	2.1	1.9	0.9	1.7	1.9	-2.3	2.4	-0.1	1.1
Handedness (chirality/laterality): Left-handed	2.3	2.8	5.3	-2.3	-1.9	-0.6	-1.0	-2.2	2.2	-2.2	-0.1	-0.2
Mood swings	1.9	3.4	6.2	-1.0	-1.2	-2.5	-2.2	-1.8	0.8	-1.9	2.5	-1.9
Loneliness, isolation	0.4	0.6	2.2	-0.2	-0.4	-0.9	-0.4	-0.8	1.5	-0.6	-0.1	-1.1
Long-standing illness, disability or infirmity	0.4	0.6	2.3	0.7	0.4	-1.5	-0.3	0.2	-0.3	0.6	1.0	1.1
Ever had bowel cancer screening	0.4	0.5	1.3	0.8	0.9	-0.8	-0.1	0.4	-0.9	0.5	1.2	-0.2
Diabetes diagnosed by doctor	0.4	0.6	2.4	-0.4	-0.8	-1.6	-0.5	-0.6	0.2	-0.1	1.2	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.9	7.1	-1.3	-0.9	2.3	0.4	-0.0	2.7	-0.7	-1.1	0.2
Friendships satisfaction	0.1	0.2	0.5	-0.3	0.2	0.2	0.4	-0.3	0.5	-0.3	0.5	-0.7
Qualifications: nursing, teaching	1.6	2.5	5.6	1.5	1.4	0.7	1.3	1.6	-2.2	2.4	-1.3	1.2
Commuting to job workplace: Walk	0.7	0.8	3.1	0.5	0.9	0.2	0.8	0.9	-0.6	0.7	0.9	1.8
Eye problems/disorders: Cataract	0.4	0.4	0.9	-0.8	-0.9	0.9	-0.3	-0.6	0.4	-0.8	0.5	-0.1
Mouth/teeth dental problems: Mouth ulcers	1.3	2.0	7.2	-0.2	-0.2	-2.0	-2.0	-1.0	0.1	-0.8	2.7	-1.0
Medication for cholesterol	0.1	0.2	0.5	0.4	0.6	-0.4	-0.2	0.7	0.6	-0.4	0.3	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	0.9	-0.7	-0.6	-0.9	-0.9	-0.4	0.7	-0.4	0.4	-0.8
Back pain experienced in last month	0.5	0.7	3.6	0.1	0.3	-1.9	-0.1	0.1	-0.4	1.3	0.9	-0.1
Mineral and other dietary supplements	0.5	0.7	2.2	0.4	0.6	1.2	0.4	1.2	-0.2	0.3	-1.5	0.6
Breast cancer (self-reported)	0.9	1.0	2.7	-0.8	-1.0	-1.6	-1.5	-1.1	1.2	-0.3	-0.1	-0.1
Asthma (self-reported)	0.7	1.4	3.1	1.5	1.8	-0.6	1.1	1.2	-0.4	1.1	1.7	-0.1
Osteoporosis (self-reported)	0.8	0.9	2.1	-0.4	-0.8	-1.4	-0.7	-1.5	-1.2	-0.9	0.8	0.2
Osteoarthritis (self-reported)	0.2	0.2	1.2	-0.1	-0.5	-0.1	-0.4	-0.3	0.4	0.4	1.1	-0.3
Medication: Aspirin	0.8	1.0	2.6	-1.0	-1.1	-1.4	-0.8	-1.6	-0.4	-1.2	0.1	0.1
Medication: Gliclazide	0.6	0.7	1.4	-1.2	-0.7	-1.0	-0.0	-0.9	0.8	-0.2	1.2	-0.8
Illnesses of father: None of the above (group 1)	0.5	0.7	1.4	-0.7	-0.7	0.6	-0.7	-0.6	1.2	-1.2	-0.9	-0.6
Smoking status: Current	0.5	0.9	2.3	-0.9	-1.1	-1.5	-0.7	-1.2	0.3	-0.9	0.2	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.9	-1.0	-0.1	-0.3	0.7	0.1	1.4	0.1	0.9	-0.9
Whole body water mass	0.4	2.0	5.1	0.2	1.0	1.6	1.4	1.0	1.2	1.2	-2.2	-1.8
Leg predicted mass (right)	0.3	1.6	5.6	-0.5	0.5	0.8	1.0	0.5	1.7	0.7	-1.8	-2.4
Arm fat mass (left)	0.3	1.3	2.8	-1.5	-1.3	-0.8	-0.3	-1.1	1.7	-0.9	-0.3	-1.6
Number of self-reported non-cancer illnesses	1.0	1.7	6.2	-1.0	-0.9	-2.5	-1.0	-1.1	1.1	-1.3	1.2	-0.7
Average weekly champagne plus white wine intake	0.1	0.1	0.3	0.5	-0.2	0.0	0.5	0.1	0.2	0.1	-0.6	-0.1
Miserableness	4.1	7.0	11.7	-2.8	-2.3	-2.4	-2.5	-2.6	2.8	-3.2	1.5	-3.4
Guilty feelings	1.0	1.5	2.9	-1.6	-1.1	-0.6	-0.0	-1.5	1.7	-1.6	-0.4	-1.2
Wears glasses or contact lenses	1.1	1.2	2.2	1.3	1.1	1.1	0.6	1.1	-1.3	1.2	0.5	1.5
Ever taken oral contraceptive pill	0.4	0.5	1.7	-0.4	-0.4	1.0	0.4	-0.1	1.3	-0.0	0.9	0.5
Hearing aid user	0.3	0.3	1.1	0.5	0.1	0.7	-1.0	0.1	-0.2	0.4	0.8	0.1
Mother’s age at death	0.0	0.1	0.2	0.1	0.3	-0.1	-0.2	0.1	-0.5	0.2	0.1	-0.1
Financial situation satisfaction	0.9	1.2	4.6	-1.1	-0.4	-0.1	0.1	-0.4	1.6	-0.2	-1.3	-2.1
Tinnitus: Yes, now most or all of the time	0.4	0.5	1.0	-0.8	-0.5	-0.5	-1.0	-0.4	0.5	-0.4	0.9	-0.9
Commuting to job workplace: Public transport	0.2	0.3	0.8	0.1	-0.2	0.4	-0.9	-0.7	0.4	-0.5	0.8	-0.2
Eye problems/disorders: Glaucoma	0.3	0.4	1.2	-0.3	-0.6	1.1	-0.2	-0.4	1.0	-0.6	-0.5	-0.3
Medication: Blood pressure	0.5	0.9	2.7	-0.9	-1.2	-0.6	-1.1	-1.6	-0.7	-0.6	-0.2	-0.6
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.7	-0.5	-0.2	-1.2	0.7	0.0	0.8	0.6	-0.5	-1.3
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.2	-0.7	-0.7	-0.3	0.0	-1.1	0.8	-0.2	0.8	-0.2
High cholesterol (Self-reported)	0.5	0.9	3.4	-0.9	-1.2	-1.8	-0.2	-1.4	0.4	-0.6	0.2	0.0
Medication: Bendroflumethiazide	0.9	1.4	2.8	1.7	1.7	-0.9	0.9	1.0	-1.5	0.9	0.9	0.1
Medication: Paracetamol	0.2	0.4	1.7	-0.6	-0.3	1.3	0.5	-0.4	-0.4	0.0	-0.4	0.7
Medication: Lisinopril	0.4	0.5	1.1	0.7	0.7	-0.6	1.0	1.0	-0.7	0.2	-0.5	0.5
Medication: Atorvastatin	0.1	0.2	0.4	-0.2	-0.1	-0.7	0.5	-0.0	-0.2	0.3	0.6	-0.5
Illnesses of father: High blood pressure	0.2	0.2	0.7	0.5	0.1	-0.8	0.1	0.1	-0.3	0.6	-0.7	-0.1
Alcohol drinker status: Never	0.8	0.9	3.8	0.1	-0.2	-1.9	-0.8	-0.5	0.1	-0.4	0.9	-1.6
Ever smoked	0.3	0.5	1.1	-0.8	-0.8	-0.3	-1.1	-0.6	0.7	-0.6	-0.5	0.5
Basal metabolic rate	0.3	1.7	4.8	-0.2	0.5	1.4	1.1	0.7	1.5	0.8	-2.2	-1.8
Leg fat percentage (left)	0.6	2.0	3.7	-1.5	-1.9	-1.4	-1.4	-1.4	1.8	-1.3	0.7	-0.9
Arm fat-free mass (left)	0.3	1.6	4.1	0.3	0.8	1.5	1.0	0.9	1.3	1.1	-2.0	-1.8
Number of operations (self-reported)	1.2	1.7	5.3	-0.7	-0.9	-0.8	-0.9	-1.8	-0.4	-0.8	2.3	-1.9
Average weekly beer plus cider intake	0.3	0.5	1.9	-0.6	-0.3	-0.9	-1.0	0.0	1.4	-0.1	0.7	-0.2
Irritability	0.5	0.8	3.7	-1.2	-0.2	0.4	-0.6	-0.7	0.4	-0.5	-0.5	-1.9
Risk taking	0.2	0.2	1.1	0.2	0.3	-0.4	-0.0	0.5	-0.4	-0.2	1.0	0.5
Ever had prostate specific antigen (PSA) test	0.7	0.8	4.4	0.5	0.2	0.8	0.6	0.5	-0.9	0.5	-2.1	0.8
Fractured/broken bones in last 5 years	0.8	1.0	3.7	-0.4	-0.3	-1.9	-0.9	-0.5	0.6	-0.5	1.4	-1.2
Age started oral contraceptive pill	3.9	4.9	10.8	3.3	2.7	-0.0	1.7	2.1	-3.1	2.7	1.0	1.0
Diastolic blood pressure, automated reading	1.5	4.6	7.7	-2.7	-2.3	-1.8	-0.4	-2.5	2.8	-2.5	1.0	-2.0
Ever depressed for a whole week	0.9	1.2	4.9	0.6	1.0	-2.2	-0.3	0.8	-1.5	0.6	0.8	-0.3
Unable to work because of sickness or disability	1.3	1.6	9.1	-0.3	-0.9	-3.0	-0.2	-1.3	-0.9	-1.1	0.7	0.6
Commuting to job workplace: Cycle	1.0	1.3	2.7	1.0	1.3	1.0	0.9	1.4	-0.7	1.3	0.2	1.6
Myopia	3.2	4.7	8.6	2.8	2.9	0.6	2.0	2.9	-2.1	2.5	0.0	1.4
Vascular/heart problems diagnosed by doctor	1.3	3.5	6.2	2.5	2.3	2.5	1.8	2.0	-1.1	2.1	-0.3	0.9
Cholesterol lowering medication	1.8	2.6	7.1	-0.6	-1.7	-2.7	-1.1	-1.9	-1.7	-0.5	2.1	1.0
Medication: Omeprazole (e.g. Zanprol)	2.4	2.9	5.5	-2.4	-1.8	-1.3	-2.2	-2.0	2.0	-1.2	0.4	-1.1
Pain experienced in last month	0.8	1.3	9.7	0.3	0.3	3.1	0.7	0.1	-1.0	-0.6	-0.0	-0.1
Supplements: Calcium	0.8	0.9	2.1	-0.7	-0.1	-1.4	0.0	-0.8	-0.7	-0.9	1.4	-1.3
Basal cell carcinoma (self-reported)	0.8	0.9	2.0	-1.1	-1.4	-0.1	-0.8	-1.4	0.4	-1.3	-0.4	-0.1
Heart attack/myocardial infarction (self-reported)	1.2	1.5	4.6	-1.4	-1.2	-2.1	-0.5	-1.2	0.5	-1.3	1.3	-0.3
Deep venous thrombosis (DVT) (self-reported)	0.6	0.7	1.8	-0.7	-0.9	-0.8	-0.1	-1.1	-0.1	-0.8	0.8	-1.4
Heart disease (siblings)	3.2	3.9	14.1	-1.6	-1.9	-2.1	-3.8	-1.8	1.4	-2.0	0.7	-0.9
Alcohol drinker status: Previous	0.9	1.0	2.1	1.2	0.6	-0.7	0.6	0.7	-1.5	1.4	1.0	0.7
Pack years of smoking	1.4	2.0	4.1	-1.4	-2.0	-0.8	-1.6	-1.7	0.9	-1.8	1.3	0.5
Impedance of whole body	0.3	1.4	5.3	-0.9	-1.6	0.4	-0.5	-1.1	-0.0	-1.6	-0.5	2.3
Leg fat mass (left)	0.4	1.7	4.0	-1.6	-1.6	-1.1	-0.5	-1.2	2.0	-1.1	-0.3	-1.5
Arm predicted mass (left)	0.3	1.4	3.5	0.3	0.6	1.3	0.9	0.7	1.2	0.9	-1.9	-1.8