TWAS hub - RASL12

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0600	0.0250	2.9e-04	0.047	0.027	0.045	0.032	0.044	1.9e-06	2.8e-04	3.3e-06	7.9e-05	4.2e-06
2	TCGA	Brain Lower Grade Glioma	0.0656	0.0320	3.1e-06	0.063	0.055	0.051	NA	0.057	1.1e-07	6.7e-07	1.9e-06	NA	4.9e-07
3	TCGA	Prostate Adenocarcinoma	0.0304	0.0188	1.8e-03	0.029	0.022	0.005	NA	0.025	4.4e-04	2.1e-03	8.0e-02	NA	1.1e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Alzheimer’s Disease (in father)	5.5	5.9	9.0	-3.0	-2.9	-0.4
Chest pain or discomfort	4.6	6.6	11.8	-3.4	-2.8	0.5
Glaucoma (self-reported)	4.1	4.9	5.3	2.2	2.1	2.3
Diabetes (mother)	3.9	5.0	10.8	1.4	1.5	3.3
Severe depression (siblings)	3.7	4.1	6.6	-2.3	-2.6	-0.8
Medication: Seretide 50 evohaler	3.7	4.3	6.8	-2.6	-2.3	0.8
Ever had stillbirth, spontaneous miscarriage or termination	3.6	3.8	5.2	-1.8	-1.7	2.3
Bipolar Disorder (2011)	3.3	3.2	3.6	1.9	1.7	1.8
Supplements: Glucosamine	3.3	4.3	5.6	2.4	2.3	1.3
Osteoarthritis (self-reported)	3.3	4.3	6.1	2.1	2.5	1.6
Fasting Glucose	3.2	3.8	6.7	-2.0	-2.6	-0.8
Supplements: Zinc	3.2	3.5	5.3	-2.3	-1.7	-1.6
Emphysema/chronic bronchitis	3.1	3.5	6.4	-2.5	-2.0	0.5
Ever had prostate specific antigen (PSA) test	2.9	3.3	4.8	1.9	2.2	1.2
Lung FEV1/FVC ratio	2.8	14.1	41.7	0.8	-0.3	-6.5
Medication: Lansoprazole	2.8	3.2	4.8	-2.0	-2.2	-0.9
Illnesses of siblings	2.7	3.8	10.8	-0.0	-0.8	-3.3
Eye problems/disorders: Glaucoma	2.7	3.2	4.4	2.1	1.9	1.2
Reason for reducing amount of alcohol drunk: Health precaution	2.5	2.9	3.1	1.8	1.8	1.6
Smoking status: Previous	2.5	3.7	6.3	-2.5	-1.9	1.2
Diabetes (father)	2.4	3.0	6.3	1.2	1.1	2.5
Pulse wave reflection index	2.4	3.0	5.3	-1.8	-2.3	-0.7
Relative age voice broke	2.3	3.5	5.7	-1.2	-1.8	-2.4
Illnesses of father: High blood pressure	2.3	2.8	8.0	-0.1	0.6	2.8
Depression (self-reported)	2.2	2.6	3.2	-1.6	-1.4	-1.8
Tense / ‘highly strung’	2.2	3.7	6.1	-2.0	-1.0	2.5
Supplements: Fish oil (including cod liver oil)	2.2	2.8	3.8	1.3	1.9	1.8
Unable to work because of sickness or disability	2.2	2.8	5.0	-2.2	-1.8	0.2
Angina	2.1	2.8	4.7	-2.2	-1.5	-1.2
High blood pressure (siblings)	2.1	3.0	5.0	-1.6	-1.1	2.2
Had major operations	2.1	2.4	4.1	-2.0	-1.4	1.1
Major Depression (MDD)	2.0	2.4	3.5	-1.8	-1.9	-0.7
Pulse rate	2.0	3.3	4.3	1.3	2.1	2.0
Commuting to job workplace: Walk	2.0	2.2	6.5	-0.2	-0.1	-2.6
Back pain experienced in last month	2.0	3.0	5.4	-2.3	-1.9	0.1
Wheeze or whistling in the chest in last year	1.9	3.3	7.5	-1.4	-0.8	2.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.9	4.1	11.0	1.1	0.2	-3.3
Fractured/broken bones in last 5 years	1.9	2.4	3.6	-1.9	-1.9	-0.1
Eye problems/disorders: None of the above	1.8	2.1	3.8	-1.3	-0.9	-1.9
Loud music exposure frequency	1.7	1.9	3.5	-1.9	-1.3	0.6
Angina (self-reported)	1.7	2.2	3.2	-1.8	-1.2	-1.4
Worry (Nagel 2018)	1.6	3.3	6.7	-2.6	-1.8	0.2
Primary Biliary Cirrhosis	1.6	2.3	3.3	1.8	1.3	-1.4
Type 2 Diabetes (T2D) (2012)	1.6	1.8	2.2	-1.0	-1.5	-1.4
Pulse wave Arterial Stiffness index	1.6	1.9	2.8	-1.7	-1.6	0.3
Pulse wave peak to peak time	1.6	1.9	3.0	1.7	1.7	-0.3
Age at last live birth	1.6	2.3	3.0	-1.5	-1.7	-1.3
Relative age of first facial hair	1.5	3.1	3.9	-1.4	-2.0	-1.9
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.4	3.4	-1.8	-1.0	1.7
Medication: Atorvastatin	1.5	1.8	2.8	-1.4	-1.7	0.8
Alzheimer’s Disease (including proxy)	1.4	2.0	3.2	-1.8	-1.5	-0.6
Financial difficulties in last 2 years	1.4	1.9	3.8	0.5	1.3	2.0
Lung cancer (father)	1.4	1.6	2.0	-1.0	-1.4	-1.4
Hair/balding pattern: Pattern 4	1.4	3.3	4.6	1.7	1.6	2.1
Overall health rating	1.4	2.9	4.8	-2.2	-1.9	0.6
Wears glasses or contact lenses	1.4	1.6	2.8	-1.3	-1.7	-0.4
Number of operations (self-reported)	1.4	2.1	3.6	-1.9	-1.4	0.8
Heart disease (siblings)	1.4	1.7	2.6	1.0	1.2	1.6
Crohns Disease (2017)	1.3	2.8	3.5	-1.9	-1.9	-1.2
High blood pressure	1.3	3.5	8.7	-1.4	-0.2	3.0
Stomach or abdominal pain in last month	1.3	1.6	2.5	-1.6	-1.5	0.2
Pain all over the body in last month	1.3	1.4	2.5	-1.2	-0.6	1.6
Birth weight of first child	1.3	2.3	3.0	-1.6	-1.7	-1.2
Birth weight	1.3	2.8	4.1	-1.3	-2.0	-1.6
Number of full brothers	1.3	1.7	3.1	-1.8	-1.2	-0.6
Medication: Allopurinol	1.3	1.8	2.7	-1.1	-1.2	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.8	4.2	-2.0	-2.0	-0.4
Verbal and Numeric Reasoning (VNR)	1.2	2.8	4.7	-1.6	-1.0	-2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	2.4	-0.9	-1.2	-1.5
Leg pain on walking	1.2	1.6	2.8	1.4	1.7	0.2
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	2.5	-1.3	-1.6	0.2
Illnesses of father: None of the above (group 1)	1.2	1.4	2.5	-0.9	-1.0	-1.6
Commuting to job workplace: Public transport	1.2	1.4	2.0	1.2	1.4	-0.9
Frequency of depressed mood in last 2 weeks	1.1	1.5	2.7	-1.6	-1.0	-0.9
Hand grip strength (right)	1.1	3.0	4.2	-2.0	-2.0	-1.0
Hair/balding pattern: Pattern 2	1.1	1.4	2.7	-1.2	-1.6	-0.1
Father’s age at death	1.1	1.5	4.1	0.3	0.5	-2.0
Noisy workplace	1.1	1.4	2.9	-1.7	-1.1	0.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.4	9.7	-0.2	-0.6	-3.1
Number of children fathered	1.1	1.3	1.6	1.3	1.1	1.0
Guilty feelings	1.1	1.6	3.2	-1.8	-0.9	-0.8
Diastolic blood pressure, automated reading	1.1	3.5	10.2	-0.2	0.5	3.2
Commuting to job workplace: Cycle	1.1	1.3	1.7	1.1	1.3	-1.0
HDL Cholesterol	1.0	1.6	2.5	1.6	1.5	-0.3
Blood Platelet Count	1.0	11.5	17.0	2.1	3.6	4.1
Hand grip strength (left)	1.0	2.6	4.0	-1.8	-2.0	-0.8
Qualifications: CSEs or equivalent	1.0	1.3	3.2	-0.6	-0.5	1.8
Impedance of leg (left)	1.0	5.0	7.2	-2.7	-2.7	0.8
Number of live births	1.0	1.4	1.9	0.9	1.2	1.4
Gout (self-reported)	1.0	1.4	2.7	-0.8	-1.0	-1.6
Age at first live birth	1.0	1.7	2.9	-1.1	-1.1	-1.7
Family relationship satisfaction	1.0	1.3	2.8	0.8	1.7	0.6
Medication: Blood pressure	1.0	1.8	2.8	-1.4	-0.8	1.7
Rheumatoid Arthritis	0.9	1.2	1.6	1.2	1.2	0.8
Waist Hip Ratio (WHR)	0.9	3.9	5.1	-2.0	-2.3	-1.6
Respiratory disease	0.9	2.1	2.4	-1.5	-1.3	1.5
Past tobacco smoking	0.9	1.6	2.8	1.7	1.2	-0.7
Hair/balding pattern: Pattern 3	0.9	1.4	2.1	1.1	1.5	0.9
Forced expiratory volume in 1-second (FEV1)	0.9	3.1	9.2	0.2	-0.2	-3.0
Suffer from ‘nerves’	0.9	1.5	2.3	-1.5	-1.4	-0.5
Hypertension (Self-reported)	0.9	2.4	5.3	-1.4	-0.3	2.3
Illnesses of siblings: Diabetes	0.9	1.1	2.9	-0.2	0.5	1.7
Diabetes diagnosed by doctor	0.9	1.5	3.0	0.4	1.2	1.7
Vascular/heart problems diagnosed by doctor	0.9	2.6	3.8	1.8	0.8	-1.9
Impedance of whole body	0.9	4.6	6.9	-2.6	-2.6	0.5
Lung FVC	0.8	4.3	6.1	2.1	1.5	-2.5
Hearing difficulty/problems: Yes	0.8	1.2	2.8	-1.7	-0.8	-0.2
Medication: Metformin	0.8	1.1	1.4	0.8	1.2	1.2
Maternal smoking around birth	0.8	1.2	2.1	-1.4	-1.2	-0.1
Chronic bronchitis/emphysema (father)	0.8	1.0	1.5	1.2	1.2	-0.1
Impedance of arm (left)	0.8	3.5	5.4	-2.2	-2.3	-0.3
Neck or shoulder pain in last month	0.8	1.2	1.6	0.8	1.3	1.2
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	1.6	-1.0	-1.3	-0.6
Knee pain experienced in last month	0.8	1.2	2.5	0.5	0.9	1.6
Friendships satisfaction	0.8	1.0	1.9	1.0	1.4	-0.1
Medication: Gliclazide	0.8	0.9	1.0	1.0	0.9	0.9
Medication: Paracetamol	0.8	1.3	2.9	0.3	0.9	1.7
Depression (Nagel 2018)	0.7	1.0	1.3	-1.1	-1.0	-0.9
Neuroticism (Nagel 2018)	0.7	1.6	3.7	-1.9	-0.9	-0.5
Alzheimer’s Disease (in mother)	0.7	0.8	1.6	-1.3	-0.8	-0.4
Prostate Cancer	0.7	1.0	1.9	1.4	1.0	0.5
Townsend deprivation index at recruitment	0.7	1.0	1.6	-1.3	-1.0	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	2.9	1.7	0.5	-1.2
Medication: Atenolol	0.7	0.9	1.1	-1.0	-1.0	0.8
Nervous feelings	0.7	1.2	2.1	-1.5	-0.8	-0.9
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	1.6	-1.3	-1.0	-0.1
Allergy	0.7	1.7	2.8	1.7	1.4	-0.6
Impedance of arm (right)	0.7	3.0	4.3	-1.9	-2.1	-1.0
Medication: Paracetamol	0.7	1.2	3.4	-0.1	0.4	1.9
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.6	-0.9	-1.3	0.1
Mineral and other dietary supplements	0.7	1.0	1.9	-0.7	-1.4	-0.8
Medication: Bendroflumethiazide	0.7	1.0	1.3	0.7	1.1	1.2
Body Mass Index (BMI) (2010)	0.6	0.9	1.9	1.4	0.9	-0.0
HbA1C	0.6	0.7	1.9	-0.3	0.1	-1.4
BMI	0.6	3.4	5.7	2.1	2.4	0.2
Allergy or Eczema	0.6	1.6	2.4	-1.6	-1.5	-0.3
Type 2 Diabetes (T2D) (2018)	0.6	1.2	2.3	0.8	1.5	0.8
Age when periods started (menarche)	0.6	1.6	4.0	-0.1	-0.8	-2.0
Heart attack	0.6	0.8	1.5	-1.2	-0.8	0.0
Time employed in main current job	0.6	0.6	1.5	0.5	0.4	1.2
Standing height	0.6	5.5	9.0	-3.0	-2.6	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	2.0	-1.4	-1.0	-0.1
Medication: Amlodipine	0.6	0.8	1.6	-1.3	-0.7	-0.5
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.4	-0.2	0.1	1.6
Exposure to tobacco smoke outside home	0.6	0.8	2.3	-0.2	0.4	1.5
Comparative body size at age 10	0.6	1.7	3.3	1.0	0.8	-1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.2	1.1	0.9	0.4
Asthma (self-reported)	0.6	1.1	2.9	-0.4	-0.5	1.7
Osteoporosis (self-reported)	0.6	0.7	1.1	-1.1	-1.0	-0.1
Medication: Lisinopril	0.6	0.7	1.5	-0.7	-0.5	1.2
Irritable Bowel Disease (IBD)	0.5	1.2	2.1	-1.4	-1.0	-0.6
Reaction Time	0.5	1.0	2.0	1.4	0.9	0.5
Blood White Count	0.5	3.6	4.2	1.6	2.1	1.9
Systolic Blood Pressure	0.5	2.3	3.0	-1.6	-1.1	1.7
Chronotype (morning person)	0.5	1.2	1.8	1.3	1.3	0.4
Ever had hysterectomy (womb removed)	0.5	0.5	0.8	-0.6	-0.7	-0.9
Fed-up feelings	0.5	0.9	2.2	-1.5	-0.8	-0.0
High blood pressure (mother)	0.5	0.7	1.3	0.2	0.8	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	2.1	1.1	-0.0	-1.4
Fluid intelligence score	0.5	1.1	2.0	-1.4	-0.9	-0.7
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.9	-1.4	-0.6	-0.2
Length of working week for main job	0.5	0.6	1.1	0.4	0.7	1.0
Qualifications: O levels/GCSEs or equivalent	0.5	0.8	2.4	0.1	0.3	1.5
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.1	-1.1	-0.8	-0.4
Shortness of breath walking on level ground	0.5	0.7	1.9	0.1	0.2	-1.4
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.2	0.6	1.1	0.3
Medication for pain relief, constipation, heartburn	0.5	0.9	2.3	0.6	-0.3	-1.5
Handedness (chirality/laterality): Left-handed	0.5	0.5	1.6	-0.1	0.2	-1.3
Number of self-reported non-cancer illnesses	0.5	0.9	1.2	-1.1	-0.6	1.0
Ever taken oral contraceptive pill	0.5	0.5	0.7	-0.3	-0.8	-0.9
Ever depressed for a whole week	0.5	0.6	0.8	-0.9	-0.8	-0.4
Basal cell carcinoma (self-reported)	0.5	0.6	1.2	1.1	0.3	-0.7
Heart attack/myocardial infarction (self-reported)	0.5	0.7	1.5	-1.2	-0.8	0.0
Intelligence (Savage-Jansen 2018)	0.4	1.1	1.5	-1.2	-0.7	-1.2
Ovarian Cancer	0.4	0.5	1.4	-0.2	0.3	-1.2
Mean Putamen Volume	0.4	0.4	1.3	-0.1	-0.2	-1.1
Heel T-Score	0.4	3.2	6.0	2.4	0.1	-1.9
Average weekly spirits intake	0.4	0.5	1.4	0.0	-0.0	-1.2
Medication for hormone replacement therapy	0.4	0.5	0.7	-0.3	-0.8	-0.8
Pack years adult smoking proportion	0.4	0.6	1.2	-1.1	-0.8	-0.1
Impedance of leg (right)	0.4	2.1	3.0	-1.7	-1.7	0.6
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.3	-1.1	-1.0	-0.4
Sitting height	0.4	2.7	4.3	-2.1	-1.7	-0.9
Worrier / anxious feelings	0.4	0.7	1.8	-1.4	-0.6	-0.1
Happiness	0.4	0.4	0.8	-0.9	-0.4	0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.7	-0.9	-0.3	-1.3
Asthma	0.4	0.8	2.1	-0.2	-0.4	1.4
Pulse rate, automated reading	0.4	1.4	2.4	1.4	1.6	0.2
Alcohol intake frequency.	0.4	1.0	2.8	0.2	0.1	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	0.8	-0.7	-0.9	0.0
Qualifications: nursing, teaching	0.4	0.7	1.0	0.3	1.0	-1.0
Eye problems/disorders: Cataract	0.4	0.4	1.0	-0.3	-0.4	1.0
Medication for cholesterol	0.4	0.7	1.3	1.2	0.8	-0.0
Miserableness	0.4	0.7	2.0	-1.4	-0.2	-0.1
Mother’s age at death	0.4	0.5	0.7	0.6	0.6	0.8
Ever smoked	0.4	0.6	0.9	-0.9	-1.0	0.5
Irritability	0.4	0.6	1.8	-1.3	-0.2	0.2
Schizophrenia (2018)	0.3	0.5	0.9	-1.0	-0.8	0.2
Crohns Disease (2012)	0.3	0.5	1.5	-0.1	-0.3	-1.2
Blood Eosinophil Count	0.3	2.2	2.3	-1.5	-1.5	1.4
Blood Red Count	0.3	3.0	5.1	0.2	2.2	2.0
Height	0.3	5.6	10.5	-3.2	-2.5	0.6
Smoking Status	0.3	0.7	1.3	-1.1	-0.8	0.3
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.1	-0.0	0.1	-1.1
Body mass index (BMI)	0.3	1.1	2.0	1.1	1.4	0.3
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	0.7	-0.0	-0.5	-0.9
Neuroticism score	0.3	0.7	1.4	-1.2	-0.0	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.7	-0.9	-0.6	-0.2
Exposure to tobacco smoke at home	0.3	0.3	0.6	-0.4	-0.3	-0.8
Peak expiratory flow (PEF)	0.3	0.7	1.9	-0.1	-0.6	-1.4
Blood clot in the leg (DVT)	0.3	0.4	0.7	0.9	0.1	-0.7
Headache pain in last month	0.3	0.5	1.0	-1.0	-0.5	-0.4
Health satisfaction	0.3	0.3	0.9	0.3	0.2	-0.9
Breast cancer (self-reported)	0.3	0.4	1.0	1.0	0.5	-0.2
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.0	0.1	-0.1	-1.0
Age started oral contraceptive pill	0.3	0.4	0.6	0.6	0.3	-0.8
Cholesterol lowering medication	0.3	0.5	1.3	0.2	1.2	0.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	0.6	-0.5	-0.5	0.8
Bipolar Disorder or Schizophrenia	0.2	0.4	0.5	-0.7	-0.7	0.6
Schizophrenia vs Biploar Disorder	0.2	0.3	0.5	-0.7	-0.6	0.2
Coronary Artery Disease (CAD)	0.2	0.2	0.4	0.3	-0.6	0.3
LDL Cholesterol	0.2	0.4	1.2	-0.1	0.1	1.1
Neuroticism (2016)	0.2	0.3	1.0	-1.0	0.0	-0.2
Ulcerative Colitis	0.2	0.2	0.5	0.3	0.7	0.2
Cardiovascular Disease	0.2	0.6	1.0	-1.0	-0.1	0.8
Neuroticism	0.2	0.4	1.2	-1.1	0.0	0.2
Number of treatments/medications taken	0.2	0.4	1.3	-0.1	0.2	1.1
Sensitivity / hurt feelings	0.2	0.3	0.9	-1.0	-0.3	-0.1
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.4	0.6	0.5	0.4
Trunk fat percentage	0.2	0.6	1.0	-1.0	-0.7	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.5	-0.4	-0.1	-0.7
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.4	0.6	0.0	-0.4
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.7	0.1	-0.2	0.8
Had menopause	0.2	0.3	0.4	-0.3	-0.7	-0.6
Qualifications: None of the above	0.2	0.4	0.6	0.8	0.6	-0.6
Diabetes (self-reported)	0.2	0.3	0.7	-0.6	0.1	0.8
Medication: Simvastatin	0.2	0.3	0.4	0.0	0.6	-0.6
Hip circumference	0.2	0.7	1.2	0.7	1.1	0.5
Alcohol intake versus 10 years previously	0.2	0.4	0.9	-0.4	-0.1	-1.0
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.6	0.1	0.8	0.2
Prospective memory result	0.2	0.2	0.4	-0.2	-0.6	0.4
Illnesses of mother	0.2	0.2	0.6	-0.1	-0.1	-0.8
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.7	0.1	-0.0	-0.8
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.9	-0.1	0.1	-0.9
Forced vital capacity (FVC), Best measure	0.2	0.6	1.3	-0.5	-0.6	-1.1
Worry too long after embarrassment	0.2	0.3	0.8	0.4	0.9	0.0
Medication: Blood pressure	0.2	0.3	0.4	-0.7	-0.4	0.6
Medication: Ibuprofen	0.2	0.2	0.5	0.4	0.7	-0.3
Medication: Omeprazole	0.2	0.3	0.4	-0.5	-0.5	0.7
Supplements: Vitamin C	0.2	0.2	0.4	-0.6	-0.3	-0.5
Loneliness, isolation	0.2	0.3	0.7	0.2	0.9	0.4
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.5	-0.3	0.7	0.7
Medication: Aspirin	0.2	0.2	0.6	-0.8	0.0	0.3
Smoking status: Current	0.2	0.4	0.5	0.7	0.7	0.4
Alcohol drinker status: Never	0.2	0.3	0.5	0.3	0.7	0.5
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.3	0.5	-0.1	-0.5
Alcohol drinker status: Previous	0.2	0.2	0.5	-0.2	-0.1	-0.7
Pack years of smoking	0.2	0.2	0.5	-0.7	-0.4	-0.1
Bipolar Disorder (2018)	0.1	0.2	0.5	0.1	-0.1	0.7
Depressed Affect (Nagel 2018)	0.1	0.2	0.3	-0.6	0.3	0.1
Ulcerative Colitis (UC)	0.1	0.2	0.3	-0.5	0.3	0.6
Breast Cancer	0.1	0.3	0.4	0.5	0.5	0.6
Lupus	0.1	0.2	0.3	0.1	0.4	0.6
Schizophrenia (2014)	0.1	0.2	0.5	0.0	0.1	0.7
Systolic blood pressure, automated reading	0.1	0.3	1.0	-0.1	0.0	1.0
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.2	-0.4	0.2	0.3
Vitamin and mineral supplements	0.1	0.2	0.3	0.3	-0.4	-0.5
Leg fat-free mass (left)	0.1	0.3	0.9	0.0	0.2	-0.9
Current tobacco smoking	0.1	0.2	0.4	0.3	0.4	0.6
Average weekly fortified wine intake	0.1	0.1	0.2	0.5	0.0	-0.5
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.1	-0.4	0.3	0.3
Leg predicted mass (left)	0.1	0.3	1.0	-0.0	0.2	-1.0
Trunk fat mass	0.1	0.3	0.6	-0.8	-0.5	0.1
Number of incorrect matches in round	0.1	0.2	0.5	-0.1	-0.1	-0.7
Hearing difficulty/problems with background noise	0.1	0.2	0.4	-0.7	0.1	0.4
Had other major operations	0.1	0.1	0.3	0.2	0.6	0.1
Forced vital capacity (FVC)	0.1	0.3	0.8	0.2	0.1	-0.9
Mouth/teeth dental problems	0.1	0.2	0.3	0.3	-0.5	0.4
Trunk fat-free mass	0.1	0.4	1.1	-0.2	0.1	-1.0
Falls in the last year	0.1	0.1	0.4	-0.6	0.1	-0.1
Mouth/teeth dental problems: Dentures	0.1	0.1	0.2	0.0	0.4	-0.5
Medication: Cholesterol lowering	0.1	0.1	0.2	-0.0	0.3	0.5
Trunk predicted mass	0.1	0.4	1.0	-0.1	0.2	-1.0
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.4	0.2	-0.3	-0.6
Leg fat percentage (right)	0.1	0.3	0.5	0.4	0.7	0.3
Qualifications: College or University degree	0.1	0.3	0.5	0.6	0.7	-0.3
Migraine (self-reported)	0.1	0.1	0.3	-0.1	-0.1	-0.6
Mean time to correctly identify matches	0.1	0.3	0.5	0.7	0.5	0.1
Heart disease (mother)	0.1	0.1	0.1	-0.2	-0.3	0.4
Comparative height size at age 10	0.1	0.7	1.3	-1.1	-0.8	0.4
Number of full sisters	0.1	0.1	0.2	-0.2	-0.1	0.4
Medication: Aspirin	0.1	0.1	0.2	-0.4	0.4	0.3
Whole body fat-free mass	0.1	0.3	0.9	-0.3	-0.1	-1.0
Leg fat-free mass (right)	0.1	0.5	1.1	-0.4	-0.3	-1.1
Average weekly red wine intake	0.1	0.1	0.2	-0.5	-0.0	0.1
Mood swings	0.1	0.1	0.2	-0.5	0.4	0.2
Long-standing illness, disability or infirmity	0.1	0.1	0.3	-0.5	-0.2	0.2
Ever had bowel cancer screening	0.1	0.1	0.2	-0.4	0.5	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.2	0.4	0.3	0.6	-0.0
Whole body water mass	0.1	0.3	0.9	-0.2	0.0	-1.0
Leg predicted mass (right)	0.1	0.4	0.9	-0.4	-0.3	-1.0
Average weekly champagne plus white wine intake	0.1	0.1	0.3	-0.1	0.3	0.5
Hearing aid user	0.1	0.1	0.2	-0.4	0.0	0.3
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.4	-0.2	0.3	0.6
High cholesterol (Self-reported)	0.1	0.2	0.6	0.1	0.3	-0.8
Average weekly beer plus cider intake	0.1	0.2	0.3	-0.5	-0.5	-0.2
Risk taking	0.1	0.1	0.1	-0.3	-0.4	0.0
Myopia	0.1	0.1	0.3	0.2	0.5	-0.1
Pain experienced in last month	0.1	0.2	0.4	0.3	0.2	-0.6
Supplements: Calcium	0.1	0.2	0.3	-0.4	-0.5	0.2
Age at First Birth	0.0	0.1	0.1	0.3	-0.1	-0.4
Triglycerides	0.0	0.1	0.1	-0.1	0.3	0.2
Hypothyroidism (self reported)	0.0	0.0	0.1	0.2	-0.1	0.2
Hair Pigment	0.0	0.7	1.8	0.4	-0.2	-1.3
Tanning	0.0	0.6	1.4	-1.2	-0.4	0.5
Medication: Co-codamol	0.0	0.0	0.1	-0.1	-0.1	0.2
Taking other prescription medications	0.0	0.0	0.1	-0.1	-0.1	0.3
Serious illness, injury or assault to yourself	0.0	0.0	0.1	0.3	0.2	-0.2
Multivitamins +/- minerals	0.0	0.0	0.1	0.1	0.3	-0.1
Medication: Levothyroxine sodium	0.0	0.0	0.0	-0.1	-0.2	-0.0
Waist circumference	0.0	0.0	0.1	-0.1	0.3	0.1
Alcohol usually taken with meals	0.0	0.0	0.1	0.4	0.0	0.0
Medication: Ramipril	0.0	0.0	0.1	-0.3	0.1	0.1
Weight	0.0	0.0	0.0	-0.2	0.2	-0.0
Arm fat percentage (right)	0.0	0.2	0.4	0.3	0.6	-0.3
Arm fat mass (right)	0.0	0.1	0.1	0.0	0.4	-0.3
Breastfed as a baby	0.0	0.0	0.0	0.0	-0.0	0.1
Hypothyroidism/myxoedema (self-reported)	0.0	0.1	0.2	-0.1	-0.4	-0.2
Body fat percentage	0.0	0.2	0.5	-0.3	-0.0	0.7
Arm fat-free mass (right)	0.0	0.1	0.1	-0.3	-0.1	-0.2
Whole body fat mass	0.0	0.1	0.2	-0.4	0.1	0.4
Leg fat mass (right)	0.0	0.2	0.4	0.3	0.6	0.0
Arm predicted mass (right)	0.0	0.2	0.2	-0.4	-0.3	-0.5
Illnesses of father: Heart disease	0.0	0.0	0.1	-0.2	-0.3	0.1
Arm fat percentage (left)	0.0	0.2	0.3	0.3	0.6	-0.2
Arm fat mass (left)	0.0	0.1	0.3	0.2	0.6	-0.3
Financial situation satisfaction	0.0	0.0	0.1	0.0	0.4	-0.0
Basal metabolic rate	0.0	0.2	0.6	-0.2	0.1	-0.8
Leg fat percentage (left)	0.0	0.0	0.0	-0.1	0.1	0.2
Arm fat-free mass (left)	0.0	0.0	0.0	-0.2	0.2	-0.1
Leg fat mass (left)	0.0	0.0	0.1	-0.0	0.3	-0.1
Arm predicted mass (left)	0.0	0.1	0.3	-0.3	0.0	-0.6

Hub : Genes

RASL12

Models

Trait associations