TWAS hub - RBBP6

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Glioblastoma Multiforme	0.219	0.093	0.0001	0.157	0.169	0.108	NA	0.144	1.7e-05	7.8e-06	0.00036	NA	3.8e-05
2	TCGA	Liver Hepatocellular Carcinoma	0.131	0.062	0.0070	0.011	0.057	0.014	NA	0.014	9.2e-02	1.2e-03	0.07000	NA	7.3e-02
3	TCGA	Pheochromocytoma and Paraganglioma	0.169	0.075	0.0086	0.033	0.046	0.056	NA	0.050	1.8e-02	6.6e-03	0.00300	NA	4.6e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Impedance of arm (right)	3.5	16.2	46.4	-6.8	-1.5
Impedance of arm (left)	3.3	15.1	42.2	-6.5	-1.8
Impedance of whole body	2.6	13.1	37.8	-6.2	-1.3
Body mass index (BMI)	2.5	10.6	31.8	5.6	0.3
Chronotype (morning person)	2.4	5.5	15.4	3.9	1.0
Handedness (chirality/laterality): Left-handed	2.4	2.9	6.7	1.4	-2.6
BMI	1.9	10.8	32.4	5.7	0.4
Impedance of leg (right)	1.9	9.4	27.7	-5.3	-0.7
Exposure to tobacco smoke outside home	1.9	2.6	6.3	1.2	2.5
Ever had stillbirth, spontaneous miscarriage or termination	1.9	2.1	3.5	-1.9	1.6
Ever depressed for a whole week	1.9	2.4	6.1	1.0	2.5
LDL Cholesterol	1.8	2.8	7.0	2.7	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.3	5.5	2.3	1.2
Impedance of leg (left)	1.7	8.4	25.1	-5.0	-0.3
Hearing difficulty/problems: Yes	1.6	2.4	3.9	2.0	-1.8
Mean Putamen Volume	1.5	1.8	3.4	1.8	-1.4
Relative age of first facial hair	1.5	3.1	6.1	1.8	-2.5
Relative age voice broke	1.5	2.4	4.1	1.7	-2.0
Mouth/teeth dental problems: Loose teeth	1.5	1.8	3.4	-1.9	1.4
Illnesses of father: Heart disease	1.5	2.1	5.9	2.4	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	4.9	-2.2	-0.6
Number of children fathered	1.4	1.5	4.5	2.1	0.3
Breast cancer (self-reported)	1.4	1.6	4.5	-0.7	2.1
Alzheimer’s Disease (in mother)	1.3	1.5	3.5	1.0	1.9
Chronic bronchitis/emphysema (father)	1.3	1.5	4.5	0.3	-2.1
Age at first live birth	1.3	2.4	5.2	-2.3	-1.4
Supplements: Calcium	1.3	1.4	3.0	-1.7	1.1
Bipolar Disorder (2018)	1.2	1.9	5.6	-2.4	-0.2
Schizophrenia vs Biploar Disorder	1.2	1.6	3.8	1.9	1.1
Body Mass Index (BMI) (2010)	1.2	1.7	4.5	2.1	-0.7
Smoking Status	1.2	3.0	8.8	-0.3	3.0
Medication: Levothyroxine sodium	1.2	2.0	5.1	-0.9	-2.3
Suffer from ‘nerves’	1.2	1.8	4.6	0.9	-2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.2	2.5	7.4	0.3	2.7
Leg fat percentage (left)	1.2	4.4	13.2	3.6	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	4.2	2.0	0.9
Leg fat percentage (right)	1.1	4.1	12.2	3.5	0.0
Alcohol drinker status: Previous	1.1	1.3	2.8	-1.0	1.7
Leg fat mass (left)	1.1	4.4	13.2	3.6	0.1
Primary Biliary Cirrhosis	1.0	1.4	3.2	1.8	0.9
Schizophrenia (2014)	1.0	2.1	4.3	-1.4	2.1
Average weekly spirits intake	1.0	1.3	3.7	-1.9	-0.4
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	2.2	1.0	1.5
Allergy	1.0	2.2	5.5	1.1	2.3
Diabetes (self-reported)	1.0	1.5	4.3	-2.1	-0.5
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	2.1	-1.3	-1.4
Happiness	1.0	1.2	3.5	-1.9	-0.4
Asthma	1.0	1.9	5.5	-0.3	-2.4
Arm fat mass (right)	1.0	3.9	11.7	3.4	-0.3
Medication: Paracetamol	1.0	1.6	4.8	-2.2	0.3
Shortness of breath walking on level ground	1.0	1.2	3.2	-0.6	1.8
Leg fat mass (right)	1.0	4.0	12.1	3.5	-0.1
Comparative height size at age 10	1.0	5.6	14.4	-3.8	1.6
Age at last live birth	1.0	1.5	3.4	-1.9	-1.0
Arm fat mass (left)	1.0	4.2	12.7	3.6	-0.2
Myopia	1.0	1.5	2.4	-1.5	1.5
Bipolar Disorder or Schizophrenia	0.9	2.3	5.4	-2.3	1.2
Height	0.9	17.0	50.8	-7.1	0.3
Hayfever, allergic rhinitis or eczema	0.9	1.9	3.0	-1.7	-1.7
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.8	0.7	-1.7
Waist circumference	0.9	3.1	9.4	3.1	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	2.9	1.7	-1.1
Tense / ‘highly strung’	0.9	1.6	4.7	-2.2	-0.1
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	2.5	1.1	-1.6
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	1.7	-1.2	-1.3
Alcohol intake frequency.	0.9	2.0	4.5	1.3	2.1
Chest pain or discomfort	0.9	1.2	2.3	1.5	-1.2
Arm fat percentage (left)	0.9	3.7	10.2	3.2	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	4.2	2.1	0.2
Asthma (self-reported)	0.9	1.9	5.4	-0.4	-2.3
Pain type(s) experienced in last month: Hip pain	0.9	1.1	3.1	1.8	0.5
Schizophrenia (2018)	0.8	1.6	3.4	-1.2	1.8
Ovarian Cancer	0.8	1.1	3.3	0.2	1.8
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	2.0	1.4	-1.1
Angina	0.8	1.0	2.0	1.1	1.4
Hair/balding pattern: Pattern 2	0.8	1.0	1.7	-1.1	1.3
Fluid intelligence score	0.8	1.6	3.2	1.8	-1.3
Arm fat percentage (right)	0.8	3.2	8.8	3.0	-0.9
Standing height	0.8	8.4	25.0	-5.0	0.3
Length of working week for main job	0.8	0.9	2.7	-1.6	0.2
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	4.7	0.0	-2.2
Medication: Ventolin 100micrograms inhaler	0.8	1.0	2.3	-1.5	0.9
Migraine (self-reported)	0.8	1.0	1.8	-1.3	-1.1
Leg pain on walking	0.8	1.0	2.5	0.7	1.6
Knee pain experienced in last month	0.8	1.3	2.6	1.6	-1.1
Diabetes diagnosed by doctor	0.8	1.3	4.0	-2.0	-0.0
Illnesses of father: None of the above (group 1)	0.8	1.0	1.8	-1.1	1.3
Wears glasses or contact lenses	0.8	1.0	2.7	0.4	-1.7
Diastolic blood pressure, automated reading	0.8	2.4	5.0	1.4	-2.2
Age at First Birth	0.7	1.0	2.4	-0.8	-1.6
Bipolar Disorder (2011)	0.7	0.7	1.7	-1.3	0.5
Allergy or Eczema	0.7	2.0	3.2	-1.6	-1.8
Hypothyroidism (self reported)	0.7	1.6	4.7	-0.2	-2.2
Neuroticism	0.7	1.6	4.6	-2.1	-0.5
Pack years adult smoking proportion	0.7	1.1	2.8	0.8	1.7
Current tobacco smoking	0.7	1.1	3.4	0.2	1.8
Medication: Atenolol	0.7	0.9	2.2	1.5	0.7
Pain all over the body in last month	0.7	0.8	2.3	1.5	0.2
Falls in the last year	0.7	0.9	1.9	1.4	-1.0
Exposure to tobacco smoke at home	0.7	0.8	2.4	-0.3	1.6
Chronic bronchitis/emphysema (mother)	0.7	0.9	2.4	-0.4	-1.6
Arm fat-free mass (right)	0.7	3.5	9.5	3.1	0.9
Angina (self-reported)	0.7	0.9	1.8	1.0	1.4
Whole body fat mass	0.7	2.7	8.0	2.8	-0.5
Arm predicted mass (right)	0.7	3.8	10.0	3.2	1.1
Had major operations	0.7	0.9	2.6	-0.1	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	2.4	1.6	-0.2
Friendships satisfaction	0.7	0.9	2.5	0.5	-1.6
Osteoporosis (self-reported)	0.7	0.8	2.3	-1.5	-0.5
Medication: Aspirin	0.7	0.9	2.0	1.4	-0.8
Hearing aid user	0.7	0.8	1.6	-0.9	-1.3
Risk taking	0.7	1.0	2.5	1.6	-0.8
Worry (Nagel 2018)	0.6	1.3	2.0	-1.4	-1.4
Alzheimer’s Disease (in father)	0.6	0.7	2.0	-1.4	-0.0
Type 2 Diabetes (T2D) (2018)	0.6	1.2	2.1	-1.5	-1.2
Medication for hormone replacement therapy	0.6	0.7	1.5	-0.7	1.2
Fed-up feelings	0.6	1.0	3.1	-0.0	1.8
Age when periods started (menarche)	0.6	1.4	2.1	-1.4	-1.4
Stomach or abdominal pain in last month	0.6	0.7	1.2	1.1	-1.0
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.8	0.5	1.3
Weight	0.6	3.1	9.1	3.0	0.3
Hip circumference	0.6	2.6	7.8	2.8	-0.1
Hair/balding pattern: Pattern 4	0.6	1.5	3.9	2.0	0.7
Body fat percentage	0.6	2.4	6.8	2.6	-0.6
Eye problems/disorders: None of the above	0.6	0.7	1.1	1.1	1.0
Emphysema/chronic bronchitis	0.6	0.7	2.0	-1.4	0.3
Number of full sisters	0.6	0.7	2.1	1.4	-0.2
Qualifications: nursing, teaching	0.6	1.0	2.8	-0.2	-1.7
Commuting to job workplace: Walk	0.6	0.7	1.8	0.4	1.4
Mineral and other dietary supplements	0.6	0.8	2.2	1.5	0.2
Osteoarthritis (self-reported)	0.6	0.8	1.4	1.2	-1.0
Arm fat-free mass (left)	0.6	3.1	8.4	2.9	0.9
Pack years of smoking	0.6	0.9	2.6	0.4	1.6
Reaction Time	0.5	0.9	2.3	-1.5	0.6
Prostate Cancer	0.5	0.8	2.2	-0.2	1.5
Crohns Disease (2012)	0.5	0.8	2.4	-0.1	1.6
Lupus	0.5	0.8	2.3	-1.5	-0.1
Diabetes (father)	0.5	0.6	1.2	0.7	-1.1
Severe depression (siblings)	0.5	0.5	0.8	0.9	-0.9
Townsend deprivation index at recruitment	0.5	0.7	1.5	0.7	1.2
Qualifications: CSEs or equivalent	0.5	0.7	1.1	-0.9	1.1
Hearing difficulty/problems with background noise	0.5	0.8	2.2	1.5	-0.5
Time employed in main current job	0.5	0.6	1.7	-1.3	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.7	2.0	0.4	-1.4
Medication: Lansoprazole	0.5	0.6	1.7	0.4	1.3
Forced vital capacity (FVC), Best measure	0.5	1.9	3.8	-2.0	1.3
Wheeze or whistling in the chest in last year	0.5	0.9	2.0	-1.4	-0.8
Medication for pain relief, constipation, heartburn	0.5	0.8	1.4	1.0	-1.2
Medication: Seretide 50 evohaler	0.5	0.5	1.3	0.5	-1.1
Supplements: Vitamin C	0.5	0.6	1.8	-0.0	-1.3
Illnesses of siblings: Diabetes	0.5	0.6	1.3	-0.6	-1.1
Leg fat-free mass (right)	0.5	2.4	7.3	2.7	0.1
Smoking status: Current	0.5	0.8	2.4	-0.0	1.6
Leg predicted mass (right)	0.5	2.4	7.3	2.7	0.2
Ever taken oral contraceptive pill	0.5	0.6	1.8	1.3	0.1
Medication: Bendroflumethiazide	0.5	0.8	2.1	1.4	-0.5
Medication: Paracetamol	0.5	0.7	2.2	-1.5	0.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.2	-0.8	1.1
Heart disease (siblings)	0.5	0.6	1.2	1.1	-0.9
Arm predicted mass (left)	0.5	2.7	7.6	2.8	0.8
Depression (Nagel 2018)	0.4	0.6	1.9	-0.0	-1.4
Crohns Disease (2017)	0.4	1.0	2.9	-1.7	0.3
Blood White Count	0.4	2.7	4.8	-2.2	-1.8
Cardiovascular Disease	0.4	1.4	2.9	1.7	-1.1
Number of treatments/medications taken	0.4	0.7	1.8	-1.4	-0.3
Systolic blood pressure, automated reading	0.4	1.1	3.3	1.8	0.1
Leg fat-free mass (left)	0.4	2.2	6.5	2.5	-0.1
Sitting height	0.4	2.6	7.7	-2.8	-0.4
Leg predicted mass (left)	0.4	2.2	6.5	2.5	-0.0
Trunk fat mass	0.4	1.8	5.3	2.3	-0.2
Number of incorrect matches in round	0.4	0.7	1.8	-1.4	0.4
Nervous feelings	0.4	0.7	2.2	0.1	-1.5
Forced vital capacity (FVC)	0.4	1.6	4.5	-2.1	0.5
Worrier / anxious feelings	0.4	0.7	2.1	-1.5	0.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	3.1	-1.8	0.9
Medication: Cholesterol lowering	0.4	0.5	1.5	0.4	1.2
Prospective memory result	0.4	0.5	1.6	0.0	-1.3
Lung cancer (father)	0.4	0.5	0.8	0.9	0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	2.1	-1.3	1.5
Pulse wave Arterial Stiffness index	0.4	0.4	1.3	-1.1	-0.1
Pulse wave peak to peak time	0.4	0.4	1.2	1.1	-0.2
Medication: Blood pressure	0.4	0.7	1.0	1.0	1.0
Medication: Aspirin	0.4	0.6	1.5	1.2	-0.4
Ever had bowel cancer screening	0.4	0.5	0.9	-1.0	-0.8
Financial situation satisfaction	0.4	0.5	1.4	1.2	-0.1
Medication: Blood pressure	0.4	0.8	1.8	0.7	-1.3
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.3	-0.5	-1.1
Illnesses of father: High blood pressure	0.4	0.5	0.7	0.8	-0.8
Basal metabolic rate	0.4	2.2	6.4	2.5	0.4
Pain experienced in last month	0.4	0.6	1.8	-1.3	-0.4
Irritable Bowel Disease (IBD)	0.3	0.7	2.1	-1.4	0.2
Coronary Artery Disease (CAD)	0.3	0.4	0.5	0.7	0.7
Fasting Glucose	0.3	0.3	0.5	0.6	-0.7
Rheumatoid Arthritis	0.3	0.4	0.8	-0.5	0.9
Systolic Blood Pressure	0.3	1.7	3.0	1.7	-1.5
Hand grip strength (left)	0.3	0.7	1.9	0.2	1.4
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.9	0.2	-0.9
Supplements: Zinc	0.3	0.3	0.9	1.0	-0.0
Medication: Metformin	0.3	0.4	0.8	-0.9	-0.7
Trunk fat percentage	0.3	1.3	3.5	1.9	-0.6
Taking other prescription medications	0.3	0.4	1.2	-1.1	-0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.7	-0.8	-0.6
Serious illness, injury or assault to yourself	0.3	0.4	0.7	-0.7	-0.8
Had other major operations	0.3	0.4	0.9	0.9	-0.5
Qualifications: None of the above	0.3	0.6	1.9	0.1	1.4
Mouth/teeth dental problems	0.3	0.5	1.4	-1.2	0.1
Heart attack	0.3	0.4	1.0	1.0	0.3
Medication: Ramipril	0.3	0.4	0.7	0.7	0.8
Medication: Simvastatin	0.3	0.5	1.5	1.2	0.1
Illnesses of siblings	0.3	0.5	1.4	-0.0	1.2
Hair/balding pattern: Pattern 3	0.3	0.5	1.2	-0.5	-1.1
Mouth/teeth dental problems: Dentures	0.3	0.4	1.1	0.4	1.0
Illnesses of mother	0.3	0.3	0.9	0.3	-0.9
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.8	0.4	0.9
Loud music exposure frequency	0.3	0.3	1.0	0.1	-1.0
Glaucoma (self-reported)	0.3	0.4	1.0	-0.3	-1.0
Medication: Amlodipine	0.3	0.4	1.0	-1.0	0.6
Comparative body size at age 10	0.3	0.7	2.0	1.4	-0.3
Medication: Allopurinol	0.3	0.5	1.0	-0.6	1.0
Pulse rate, automated reading	0.3	1.0	2.3	-0.9	-1.5
Family relationship satisfaction	0.3	0.3	0.6	-0.8	-0.6
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.6	0.6	-0.8
Whole body fat-free mass	0.3	1.8	5.1	2.3	0.5
Average weekly red wine intake	0.3	0.5	0.8	0.8	-0.9
Mood swings	0.3	0.5	0.9	0.8	0.9
Eye problems/disorders: Cataract	0.3	0.3	0.9	-0.3	-0.9
Whole body water mass	0.3	1.8	5.1	2.3	0.7
Number of self-reported non-cancer illnesses	0.3	0.5	1.4	0.1	-1.2
Average weekly champagne plus white wine intake	0.3	0.4	1.2	-0.2	-1.1
Mother’s age at death	0.3	0.4	1.0	-1.0	0.4
High cholesterol (Self-reported)	0.3	0.5	1.1	0.7	1.0
Medication: Lisinopril	0.3	0.3	0.6	-0.8	0.6
Number of operations (self-reported)	0.3	0.4	0.7	-0.8	0.7
Ever had prostate specific antigen (PSA) test	0.3	0.4	0.8	-0.9	0.6
Age started oral contraceptive pill	0.3	0.4	1.2	-1.1	-0.1
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.2	-1.5	0.6
Basal cell carcinoma (self-reported)	0.3	0.3	0.6	-0.8	0.6
Intelligence (Savage-Jansen 2018)	0.2	0.6	1.5	-0.6	-1.2
Alzheimer’s Disease (including proxy)	0.2	0.3	0.7	-0.4	0.8
Ulcerative Colitis (UC)	0.2	0.3	0.9	-0.9	0.0
Major Depression (MDD)	0.2	0.3	0.6	0.4	0.8
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.1	0.8	-1.0
Breast Cancer	0.2	0.5	1.4	0.2	1.2
HbA1C	0.2	0.2	0.4	-0.5	0.7
Triglycerides	0.2	0.3	0.8	0.9	-0.3
Blood Platelet Count	0.2	2.2	3.6	1.8	-1.9
Lung FEV1/FVC ratio	0.2	1.0	2.5	0.7	1.6
Lung FVC	0.2	1.1	3.4	0.1	1.9
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.6	0.5	-0.8
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.7	0.8	-0.5
Hand grip strength (right)	0.2	0.4	1.3	0.1	1.1
Average weekly fortified wine intake	0.2	0.3	0.6	-0.8	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.8	0.2	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.0	0.5	-1.0
High blood pressure	0.2	0.5	1.2	1.1	-0.5
High blood pressure (mother)	0.2	0.3	0.7	-0.9	0.5
Neuroticism score	0.2	0.4	1.2	-1.1	-0.1
Trunk fat-free mass	0.2	1.0	2.2	1.5	0.8
Number of live births	0.2	0.3	0.9	0.9	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.5	-0.4	0.7
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	0.4	0.7	0.7
Trunk predicted mass	0.2	0.9	1.9	1.4	0.9
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.8	0.1	-0.9
Headache pain in last month	0.2	0.3	0.6	0.7	-0.5
Gout (self-reported)	0.2	0.3	0.8	-0.1	0.9
Number of full brothers	0.2	0.2	0.6	0.1	0.8
Worry too long after embarrassment	0.2	0.3	0.9	-0.3	-0.9
Neck or shoulder pain in last month	0.2	0.3	0.4	0.6	-0.6
Medication: Ibuprofen	0.2	0.3	0.8	0.9	0.1
Medication: Omeprazole	0.2	0.3	0.5	-0.7	0.6
Mean time to correctly identify matches	0.2	0.3	0.9	-0.9	0.3
Overall health rating	0.2	0.4	0.7	0.7	-0.9
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.4	-0.6	-0.6
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.3	0.5	-0.6
Hypertension (Self-reported)	0.2	0.5	1.3	1.1	-0.4
Long-standing illness, disability or infirmity	0.2	0.3	0.7	0.9	0.3
Guilty feelings	0.2	0.3	0.8	-0.9	-0.3
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.4	-0.6	0.5
Commuting to job workplace: Public transport	0.2	0.2	0.6	0.3	0.8
Eye problems/disorders: Glaucoma	0.2	0.2	0.3	-0.6	-0.6
Medication: Atorvastatin	0.2	0.2	0.3	-0.6	-0.5
Alcohol drinker status: Never	0.2	0.2	0.5	0.4	0.7
Average weekly beer plus cider intake	0.2	0.2	0.7	0.1	0.8
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.9	0.9	0.2
Neuroticism (Nagel 2018)	0.1	0.2	0.4	-0.6	-0.5
HDL Cholesterol	0.1	0.2	0.6	0.1	-0.8
Neuroticism (2016)	0.1	0.2	0.6	-0.1	-0.8
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.2	-0.5	0.4
Heel T-Score	0.1	1.0	2.9	-0.2	1.7
Waist Hip Ratio (WHR)	0.1	0.6	1.1	-1.0	-0.9
Respiratory disease	0.1	0.1	0.3	-0.4	-0.5
Hair Pigment	0.1	1.8	5.2	2.3	0.2
Tanning	0.1	1.0	1.7	-1.1	-1.3
Diabetes (mother)	0.1	0.1	0.2	0.4	0.3
Maternal smoking around birth	0.1	0.1	0.2	0.5	0.4
Multivitamins +/- minerals	0.1	0.1	0.3	-0.1	-0.6
Supplements: Glucosamine	0.1	0.2	0.5	-0.2	-0.7
Past tobacco smoking	0.1	0.2	0.7	0.8	-0.2
Had menopause	0.1	0.1	0.1	-0.3	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.6	-0.6	-0.8
Financial difficulties in last 2 years	0.1	0.1	0.3	0.0	-0.5
Alcohol intake versus 10 years previously	0.1	0.2	0.5	0.3	0.7
Father’s age at death	0.1	0.1	0.2	-0.5	0.1
Pulse rate	0.1	0.2	0.4	0.3	-0.7
Noisy workplace	0.1	0.1	0.2	0.4	-0.4
Depression (self-reported)	0.1	0.1	0.2	0.4	0.4
Breastfed as a baby	0.1	0.1	0.3	0.4	0.5
Peak expiratory flow (PEF)	0.1	0.2	0.5	-0.7	0.2
Pulse wave reflection index	0.1	0.1	0.3	-0.6	-0.0
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.4	-0.6	-0.6
Birth weight	0.1	0.3	0.8	0.2	0.9
High blood pressure (siblings)	0.1	0.1	0.3	0.6	-0.2
Qualifications: College or University degree	0.1	0.3	0.7	-0.8	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.2	0.2	0.4
Loneliness, isolation	0.1	0.1	0.2	0.1	0.5
Back pain experienced in last month	0.1	0.2	0.3	0.6	0.5
Ever smoked	0.1	0.2	0.3	-0.6	0.4
Irritability	0.1	0.2	0.4	0.7	0.2
Commuting to job workplace: Cycle	0.1	0.2	0.4	0.1	0.7
Cholesterol lowering medication	0.1	0.1	0.2	-0.0	0.5
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.5	0.1	-0.7
Depressed Affect (Nagel 2018)	0.0	0.1	0.2	-0.3	0.4
Ulcerative Colitis	0.0	0.0	0.0	0.2	0.0
Blood Eosinophil Count	0.0	0.1	0.2	0.4	-0.1
Blood Red Count	0.0	0.1	0.1	-0.2	-0.4
Sensitivity / hurt feelings	0.0	0.1	0.2	-0.5	-0.1
Ever had hysterectomy (womb removed)	0.0	0.0	0.1	-0.0	-0.2
Vitamin and mineral supplements	0.0	0.0	0.1	-0.3	0.1
Medication: Co-codamol	0.0	0.0	0.1	0.3	0.1
Alcohol usually taken with meals	0.0	0.0	0.1	-0.3	-0.0
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.0	0.1	-0.2
Birth weight of first child	0.0	0.0	0.0	0.2	-0.1
Blood clot in the leg (DVT)	0.0	0.0	0.1	0.0	-0.4
Health satisfaction	0.0	0.1	0.2	-0.4	-0.0
Heart disease (mother)	0.0	0.0	0.1	0.4	0.0
Smoking status: Previous	0.0	0.0	0.0	-0.2	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.0	0.0	-0.0	0.1
Medication for cholesterol	0.0	0.0	0.0	0.1	-0.1
Medication: Gliclazide	0.0	0.0	0.0	-0.0	-0.1
Miserableness	0.0	0.0	0.1	-0.3	-0.2
Fractured/broken bones in last 5 years	0.0	0.0	0.0	0.1	0.0
Unable to work because of sickness or disability	0.0	0.0	0.0	-0.2	0.2

Hub : Genes

RBBP6

Models

Trait associations