TWAS hub - RBM20

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.142	0.0517	3.6e-03	0.004	NA	0.005	NA	0.005	1.4e-01	NA	1.3e-01	NA	1.2e-01
2	GTEx	Esophagus Gastroesophageal Junction	0.250	0.0930	9.1e-03	0.007	NA	-0.006	NA	-0.007	1.7e-01	NA	6.5e-01	NA	7.4e-01
3	TCGA	Brain Lower Grade Glioma	0.164	0.0419	3.3e-08	0.065	0.088	0.075	NA	0.077	6.7e-08	3.7e-10	7.8e-09	NA	4.6e-09
4	TCGA	Ovarian Serous Cystadenocarcinoma	0.053	0.0250	9.4e-03	-0.003	0.006	-0.002	NA	-0.004	5.8e-01	1.1e-01	4.6e-01	NA	8.1e-01
5	TCGA	Thyroid Carcinoma	0.065	0.0280	5.6e-03	0.033	0.021	0.067	NA	0.059	3.1e-04	3.6e-03	4.6e-07	NA	2.2e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	3	4	5
Pulse rate, automated reading	5.0	16.1	41.8	-3.6	1.9	6.5	4.7
Medication: Lansoprazole	2.6	3.0	7.2	0.6	1.2	2.4	2.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.5	3.0	5.3	1.2	-1.9	-2.1	-2.3
Type 2 Diabetes (T2D) (2012)	2.0	2.3	5.1	-2.3	-1.0	2.2	-0.7
Ever had hysterectomy (womb removed)	2.0	2.3	8.4	-1.7	-2.9	0.1	-0.4
Father’s age at death	2.0	2.6	6.6	2.6	-1.1	-2.1	-1.0
Medication: Ventolin 100micrograms inhaler	2.0	2.5	7.6	2.8	-0.2	-2.2	-0.4
Medication: Ibuprofen	2.0	2.3	5.9	2.0	0.2	-2.4	-1.3
Ever had bowel cancer screening	2.0	2.4	8.0	2.8	0.6	-1.9	-0.1
Hayfever/allergic rhinitis (self-reported)	1.9	2.5	5.6	-1.3	2.0	2.4	1.0
Lung cancer (father)	1.9	2.3	5.9	-2.2	0.8	2.4	0.3
Mouth/teeth dental problems: Dentures	1.8	3.0	8.6	1.9	-0.6	-2.9	-1.4
Ever had prostate specific antigen (PSA) test	1.8	2.1	5.2	2.3	0.8	-2.1	-0.3
Forced vital capacity (FVC)	1.7	6.5	15.0	0.9	3.5	2.2	3.9
Hypertension (Self-reported)	1.7	4.8	12.5	-3.5	-0.4	3.4	-0.1
Maternal smoking around birth	1.6	2.3	4.8	1.8	1.7	-0.6	2.2
Hearing difficulty/problems with background noise	1.6	2.5	4.9	0.8	-2.2	-1.9	-1.8
High blood pressure (siblings)	1.6	2.2	6.3	1.9	2.5	-1.0	0.2
Forced vital capacity (FVC), Best measure	1.6	5.7	13.9	0.9	2.9	2.4	3.7
Age at First Birth	1.5	2.2	6.5	0.8	-1.5	-1.3	-2.5
Hayfever, allergic rhinitis or eczema	1.5	3.3	7.2	-0.4	2.7	2.2	2.0
Myopia	1.5	2.1	6.2	1.9	-0.8	-2.5	0.0
Vascular/heart problems diagnosed by doctor	1.5	4.0	10.2	3.2	0.2	-3.1	0.3
Allergy or Eczema	1.4	3.8	9.9	-1.1	2.1	3.1	1.9
High blood pressure	1.4	3.8	10.3	-3.2	-0.7	2.9	-0.5
Fasting Glucose	1.3	1.6	4.9	-1.5	-0.2	2.2	0.9
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	2.8	-0.5	1.4	1.7	1.4
Medication: Metformin	1.3	1.8	8.3	0.5	0.4	-0.4	-2.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	5.0	0.0	-0.9	-1.7	-2.2
Number of live births	1.3	1.8	4.5	1.8	0.4	-2.1	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.3	4.2	10.6	0.5	2.2	2.3	3.3
Length of working week for main job	1.3	1.4	4.4	-0.1	0.6	2.1	1.5
Family relationship satisfaction	1.3	1.6	3.8	1.4	-0.1	-1.9	-1.5
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	6.4	0.2	-1.1	-0.8	-2.5
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.8	5.9	1.6	2.4	0.2	2.3
Financial situation satisfaction	1.3	1.6	5.1	1.5	-0.3	-2.3	-0.8
Irritability	1.3	2.2	5.6	2.4	1.6	-1.7	-0.1
Prostate Cancer	1.2	1.7	4.8	-1.0	1.2	2.2	1.0
Forced expiratory volume in 1-second (FEV1)	1.2	4.2	10.7	1.0	2.8	1.1	3.3
Pulse rate	1.2	2.0	4.8	-1.3	0.0	2.2	1.9
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	4.0	1.6	0.3	-2.0	-0.9
Headache pain in last month	1.2	2.0	3.7	1.6	-0.5	-1.9	-1.9
Age at first live birth	1.2	2.1	5.5	-1.2	1.7	2.3	0.5
Angina (self-reported)	1.2	1.6	4.4	-1.6	-0.7	2.1	-0.7
Mineral and other dietary supplements	1.2	1.6	5.9	-0.8	-0.8	0.7	-2.4
Medication: Aspirin	1.2	1.6	5.5	-0.9	-1.2	0.4	-2.4
Heart attack/myocardial infarction (self-reported)	1.2	1.6	5.1	-2.3	0.1	1.7	0.2
Alzheimer’s Disease (in mother)	1.1	1.3	3.3	-1.6	0.2	1.0	1.8
Lupus	1.1	1.7	4.5	0.2	1.6	1.1	2.1
Severe depression (siblings)	1.1	1.2	2.6	1.3	1.6	-0.0	1.4
Heart attack	1.1	1.4	5.0	-2.2	0.3	1.5	-0.1
Illnesses of siblings	1.1	1.5	4.8	-1.4	-2.2	0.3	-0.8
Impedance of arm (right)	1.1	5.0	9.4	-3.1	2.7	2.7	0.9
Number of full brothers	1.1	1.4	4.1	0.3	-1.0	-2.0	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	3.0	1.7	0.7	-0.7	1.6
Neck or shoulder pain in last month	1.1	1.6	3.7	1.4	1.9	-0.3	1.5
Smoking status: Previous	1.1	1.6	2.7	-1.6	-1.6	1.3	-1.0
Smoking status: Current	1.1	1.8	4.9	1.1	2.2	-1.1	1.2
Cardiovascular Disease	1.0	3.4	11.2	-3.3	-0.7	2.3	-0.4
Lung FVC	1.0	5.1	12.6	-0.9	0.1	3.5	3.5
Sensitivity / hurt feelings	1.0	1.6	3.5	-1.5	1.2	1.9	0.9
Angina	1.0	1.3	3.8	-1.5	-0.4	2.0	-0.6
Average weekly fortified wine intake	1.0	1.1	3.0	1.0	1.2	-0.3	1.7
Happiness	1.0	1.2	2.2	0.9	1.2	-1.2	-1.5
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	3.9	-0.7	-0.0	2.0	1.1
Alcohol intake frequency.	1.0	2.4	4.4	-2.0	-2.1	1.8	-0.4
Illnesses of father: Heart disease	1.0	1.4	3.5	-0.3	-0.6	1.9	1.8
Friendships satisfaction	1.0	1.2	3.2	1.2	-0.2	-1.2	-1.8
Back pain experienced in last month	1.0	1.4	4.4	1.2	0.8	-2.1	-0.9
Irritable Bowel Disease (IBD)	0.9	2.2	5.8	-0.5	0.7	2.4	2.1
Ulcerative Colitis (UC)	0.9	1.8	5.7	-1.0	-0.0	2.4	1.5
Coronary Artery Disease (CAD)	0.9	1.1	3.9	-1.2	-0.1	2.0	-0.0
Hypothyroidism (self reported)	0.9	2.1	6.6	1.9	0.1	-2.6	-0.6
Pack years adult smoking proportion	0.9	1.4	5.1	-2.3	-0.5	1.2	-0.3
Townsend deprivation index at recruitment	0.9	1.2	3.9	1.0	-0.3	-2.0	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	5.2	2.3	0.9	-1.9	0.9
Chest pain or discomfort	0.9	1.2	4.2	-0.5	2.0	1.0	0.9
Medication: Aspirin	0.9	1.2	3.9	-1.0	-1.0	0.5	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	2.7	1.6	-0.4	-0.3	1.6
Diabetes diagnosed by doctor	0.9	1.5	3.8	1.9	0.2	-0.7	-1.7
Fractured/broken bones in last 5 years	0.9	1.1	2.4	-1.0	-1.4	0.5	-1.6
Unable to work because of sickness or disability	0.9	1.2	3.3	1.8	0.3	-1.4	0.7
Pack years of smoking	0.9	1.4	4.8	-2.2	-0.7	1.2	-0.5
Schizophrenia vs Biploar Disorder	0.8	1.1	4.7	-0.7	0.5	2.2	0.2
Type 2 Diabetes (T2D) (2018)	0.8	1.5	4.0	2.0	0.2	-0.7	-1.8
Supplements: Zinc	0.8	0.9	2.9	1.1	-0.2	-1.7	-0.6
Medication: Levothyroxine sodium	0.8	1.3	3.3	1.6	0.7	-1.8	0.3
Pain all over the body in last month	0.8	0.8	2.4	-0.8	0.3	1.5	1.0
Impedance of arm (left)	0.8	3.9	8.5	-2.9	2.3	2.4	0.2
Breastfed as a baby	0.8	1.0	4.1	0.8	0.6	-0.1	2.0
Peak expiratory flow (PEF)	0.8	1.8	4.2	0.5	2.0	0.7	2.0
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	5.0	1.3	0.9	-2.2	-0.2
Exposure to tobacco smoke outside home	0.8	1.1	2.2	-1.5	1.0	1.3	0.9
Pulse wave peak to peak time	0.8	0.9	2.7	0.6	1.2	-0.4	1.6
Medication: Blood pressure	0.8	1.4	2.9	-1.7	-0.1	1.6	-1.2
Illnesses of siblings: Diabetes	0.8	1.0	2.8	1.7	0.5	-1.2	-0.5
Supplements: Fish oil (including cod liver oil)	0.8	1.1	4.3	0.3	0.7	-0.7	2.1
Medication: Lisinopril	0.8	1.0	2.8	-1.2	-0.3	1.7	-0.7
Commuting to job workplace: Cycle	0.8	1.0	5.0	-0.0	0.1	0.1	-2.2
Schizophrenia (2018)	0.7	1.5	3.7	0.0	-1.0	1.6	1.9
Ovarian Cancer	0.7	0.9	2.1	-0.6	-0.7	1.2	-1.5
Bipolar Disorder (2011)	0.7	0.7	1.7	-0.8	-1.3	0.7	0.8
Current tobacco smoking	0.7	1.2	3.2	0.8	1.8	-1.2	0.9
Supplements: Glucosamine	0.7	0.9	4.0	0.3	-0.5	-0.2	2.0
Medication: Atenolol	0.7	0.9	2.3	-1.2	0.8	1.5	-0.2
Alcohol intake versus 10 years previously	0.7	1.0	2.6	-0.7	-0.2	1.6	1.3
Pulse wave reflection index	0.7	0.8	2.4	-1.1	-0.7	-0.3	-1.5
Shortness of breath walking on level ground	0.7	0.9	2.6	-1.0	-1.6	0.3	-0.8
Eye problems/disorders: None of the above	0.7	0.9	1.9	0.8	-0.6	-1.4	-1.2
Medication for cholesterol	0.7	1.1	2.6	1.6	-0.2	-1.1	-1.3
Osteoporosis (self-reported)	0.7	0.8	3.3	-0.3	-0.8	1.8	0.4
Medication: Gliclazide	0.7	0.8	3.4	0.2	-0.5	-0.5	-1.9
Medication: Blood pressure	0.7	1.4	4.2	-2.1	0.9	1.2	0.6
Medication: Paracetamol	0.7	1.0	2.5	0.0	0.6	1.5	1.6
Medication: Atorvastatin	0.7	0.9	2.6	-1.6	-0.3	1.3	0.1
Risk taking	0.7	1.0	2.2	1.5	-0.0	-1.4	-0.7
Age started oral contraceptive pill	0.7	0.9	3.4	-0.7	-1.8	0.4	-0.7
Pain experienced in last month	0.7	1.2	3.9	-2.0	-1.0	0.9	0.3
Basal cell carcinoma (self-reported)	0.7	0.9	2.3	-0.5	-1.1	1.5	0.8
Crohns Disease (2012)	0.6	0.9	1.7	-1.3	-1.1	1.2	0.1
Stomach or abdominal pain in last month	0.6	0.8	2.3	1.0	0.3	-1.5	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	3.0	0.5	-0.2	-1.1	-1.7
Had menopause	0.6	0.7	2.1	-0.8	-1.5	0.5	-0.6
Allergy	0.6	1.5	4.2	0.3	-2.0	-0.9	-1.5
Diabetes (self-reported)	0.6	0.9	2.7	1.6	0.1	-0.8	-1.1
Time employed in main current job	0.6	0.7	1.6	-1.0	-1.2	-0.1	-0.9
Prospective memory result	0.6	0.7	2.4	0.6	-1.6	0.3	0.7
Illnesses of mother	0.6	0.7	3.3	0.3	-1.8	0.2	0.3
Pulse wave Arterial Stiffness index	0.6	0.7	2.0	-0.2	-1.1	0.4	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	3.0	0.8	1.7	-0.7	-0.7
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.5	1.2	-0.5	-1.2	0.3
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	2.4	-0.9	-1.6	0.6	-0.8
Blood clot in the leg (DVT)	0.6	0.8	1.8	0.4	-1.4	-1.3	-0.5
Qualifications: College or University degree	0.6	2.0	4.4	2.0	2.1	0.0	1.2
Mean time to correctly identify matches	0.6	1.2	4.9	0.5	0.0	-2.2	-1.0
Suffer from ‘nerves’	0.6	0.9	1.5	1.2	1.2	-0.9	0.7
Commuting to job workplace: Car/motor vehicle	0.6	0.6	2.8	0.4	0.3	0.3	1.7
Supplements: Vitamin C	0.6	0.7	2.2	1.5	0.4	-0.9	-0.7
Loneliness, isolation	0.6	0.9	2.9	1.7	0.1	-1.2	-0.3
Number of operations (self-reported)	0.6	0.8	3.8	-0.2	-2.0	0.4	-0.3
Impedance of whole body	0.6	3.2	7.6	-2.2	2.8	1.7	0.6
Alzheimer’s Disease (including proxy)	0.5	0.8	1.7	-1.2	-0.7	0.5	1.3
Breast Cancer	0.5	1.1	3.7	1.9	-1.0	-0.9	0.5
Mean Putamen Volume	0.5	0.5	1.6	-1.2	-0.7	-0.5	-0.6
Neuroticism (2016)	0.5	0.7	2.3	0.5	1.1	0.2	1.5
Ulcerative Colitis	0.5	0.7	1.6	-1.0	0.3	1.3	0.9
Respiratory disease	0.5	1.0	3.9	0.8	0.1	-2.0	-0.8
Lung FEV1/FVC ratio	0.5	2.8	5.8	-1.1	-2.4	-2.2	-1.4
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.0	1.4	0.0	-1.0	-0.4
Taking other prescription medications	0.5	0.7	3.1	0.4	-1.8	-0.3	-0.4
Tinnitus: Yes, but not now, but have in the past	0.5	0.6	2.0	0.7	1.4	-0.6	0.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.5	1.5	-1.2	0.2	0.4	-1.0
Chronic bronchitis/emphysema (father)	0.5	0.5	1.2	-0.3	0.9	0.8	1.1
High blood pressure (mother)	0.5	0.7	1.7	1.2	1.3	0.3	-0.5
Hair/balding pattern: Pattern 2	0.5	0.7	2.4	0.7	-0.6	-1.5	-0.0
Worrier / anxious feelings	0.5	0.9	2.3	0.0	1.2	0.7	1.5
Qualifications: A levels/AS levels or equivalent	0.5	1.1	3.0	1.1	1.7	0.7	-0.9
Depression (self-reported)	0.5	0.6	1.7	-1.3	0.8	0.9	0.0
Exposure to tobacco smoke at home	0.5	0.6	1.5	-0.9	-1.2	-0.3	-0.8
Birth weight of first child	0.5	0.8	1.9	1.4	1.1	-0.6	-0.9
Gout (self-reported)	0.5	0.7	1.8	0.3	0.8	1.0	1.3
Medication: Amlodipine	0.5	0.7	2.9	0.8	0.1	0.2	1.7
Birth weight	0.5	1.0	3.4	1.8	1.2	-0.2	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.8	-1.7	0.4	0.7	-0.4
Wheeze or whistling in the chest in last year	0.5	0.9	1.6	-1.2	-1.3	0.5	-1.1
Average weekly red wine intake	0.5	0.8	2.3	1.5	-0.2	-0.8	-1.0
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.1	-0.1	0.5	-0.7	1.4
Miserableness	0.5	0.9	3.3	0.9	1.8	-0.6	-0.2
Guilty feelings	0.5	0.8	1.5	1.1	1.2	-0.4	1.0
Wears glasses or contact lenses	0.5	0.6	2.2	-0.8	-0.5	0.0	-1.5
Medication: Bendroflumethiazide	0.5	0.7	3.3	0.5	1.8	0.2	0.3
Cholesterol lowering medication	0.5	0.7	1.8	-1.4	-0.3	1.0	0.9
Bipolar Disorder or Schizophrenia	0.4	1.1	2.8	-0.5	-1.0	1.2	1.7
Depression (Nagel 2018)	0.4	0.5	1.8	0.4	-1.4	-0.3	-0.8
Intelligence (Savage-Jansen 2018)	0.4	1.1	2.1	0.6	1.4	-1.3	-1.1
Alzheimer’s Disease (in father)	0.4	0.4	1.1	-0.5	-1.1	0.8	0.0
Crohns Disease (2017)	0.4	0.8	1.8	0.2	0.8	1.2	1.3
Schizophrenia (2014)	0.4	0.9	1.9	0.3	-1.0	1.4	1.1
Medication for hormone replacement therapy	0.4	0.4	1.2	-0.4	-0.1	1.1	0.9
Vitamin and mineral supplements	0.4	0.5	1.6	-0.4	-1.3	-0.0	-0.8
Qualifications: CSEs or equivalent	0.4	0.5	1.1	1.0	-0.8	-0.7	-0.7
Alcohol usually taken with meals	0.4	0.6	1.4	1.2	-0.9	-1.0	-0.2
Qualifications: None of the above	0.4	0.8	1.8	-1.2	-1.3	0.3	-0.7
Financial difficulties in last 2 years	0.4	0.5	1.1	-1.0	0.6	-0.1	0.9
Mouth/teeth dental problems	0.4	0.6	1.2	-0.5	0.7	1.1	0.9
Neuroticism score	0.4	0.9	3.1	1.0	1.8	-0.5	0.5
Falls in the last year	0.4	0.5	1.3	0.5	0.4	-0.9	-1.2
Glaucoma (self-reported)	0.4	0.5	2.0	-1.4	-0.1	-0.5	0.3
Chronic bronchitis/emphysema (mother)	0.4	0.5	0.9	0.6	1.0	0.6	0.9
Health satisfaction	0.4	0.5	1.6	0.1	-1.3	-0.6	-0.5
Age at last live birth	0.4	0.5	1.9	-0.1	0.5	0.6	-1.4
Mood swings	0.4	0.7	1.8	-0.5	1.3	0.2	1.3
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	2.3	-0.2	0.8	0.7	1.5
Asthma (self-reported)	0.4	0.8	2.4	0.8	-0.4	-1.6	-0.8
Illnesses of father: None of the above (group 1)	0.4	0.5	1.3	-1.0	1.1	-0.4	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	1.9	1.4	0.6	0.4	1.3
Hearing aid user	0.4	0.4	1.8	0.2	0.4	0.5	1.3
Supplements: Calcium	0.4	0.4	1.6	0.2	0.3	0.7	1.3
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.3	0.2	-1.0	-1.1	-0.3
Alcohol drinker status: Previous	0.4	0.5	1.2	-1.1	-1.0	0.3	0.3
Reaction Time	0.3	0.6	2.1	0.7	0.5	-1.4	-0.1
Rheumatoid Arthritis	0.3	0.5	1.0	-0.9	-0.0	1.0	0.7
Triglycerides	0.3	0.5	1.9	1.4	0.3	-0.3	0.7
Blood Red Count	0.3	2.6	4.9	-0.8	2.2	1.8	2.1
Neuroticism	0.3	0.6	2.2	0.7	1.5	-0.0	0.7
Hearing difficulty/problems: Yes	0.3	0.4	1.2	0.3	-1.1	-0.8	-0.5
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.2	-0.4	-0.2	0.8	1.1
Systolic blood pressure, automated reading	0.3	1.0	3.1	-0.9	-1.8	0.6	-0.9
Impedance of leg (right)	0.3	1.4	5.7	-0.8	2.4	-0.1	0.7
Relative age voice broke	0.3	0.4	1.3	0.3	-1.1	-0.7	0.4
Serious illness, injury or assault to yourself	0.3	0.4	1.2	-0.5	-0.6	-0.2	-1.1
Impedance of leg (left)	0.3	1.4	4.4	-1.4	2.1	0.5	0.5
Noisy workplace	0.3	0.3	0.9	0.9	-0.6	-0.1	0.7
Asthma	0.3	0.7	1.7	0.7	-0.5	-1.3	-1.0
Medication: Cholesterol lowering	0.3	0.4	1.3	0.9	-0.0	-0.1	-1.1
Tense / ‘highly strung’	0.3	0.6	1.1	1.0	1.1	-0.7	-0.5
Medication: Paracetamol	0.3	0.5	1.2	0.7	0.4	0.7	1.1
Comparative body size at age 10	0.3	0.7	1.5	1.2	-0.0	1.2	0.9
Medication: Allopurinol	0.3	0.4	1.2	0.3	0.8	0.4	1.1
Medication: Omeprazole	0.3	0.4	1.4	0.5	-1.2	-0.4	0.0
Number of full sisters	0.3	0.4	1.5	0.3	0.5	-1.2	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.0	0.2	0.5	1.0	-0.3
Commuting to job workplace: Walk	0.3	0.3	0.6	-0.8	0.8	0.7	-0.0
Breast cancer (self-reported)	0.3	0.3	1.0	-1.0	0.5	0.5	0.2
High cholesterol (Self-reported)	0.3	0.5	1.1	0.8	-0.9	-0.1	1.0
Average weekly beer plus cider intake	0.3	0.5	1.2	1.1	0.4	-1.0	0.1
Diastolic blood pressure, automated reading	0.3	0.9	3.6	-0.9	-0.0	1.9	0.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.1	0.4	-1.0	0.5	0.8
Neuroticism (Nagel 2018)	0.2	0.4	1.4	0.5	1.2	-0.1	0.7
Worry (Nagel 2018)	0.2	0.5	1.4	0.3	1.2	0.2	0.9
Body Mass Index (BMI) (2010)	0.2	0.2	0.6	-0.8	-0.7	-0.0	0.5
HDL Cholesterol	0.2	0.3	1.0	0.0	-1.0	-0.4	0.5
LDL Cholesterol	0.2	0.3	1.1	0.4	1.0	-0.2	0.2
Primary Biliary Cirrhosis	0.2	0.3	1.6	1.3	-0.3	-0.2	0.1
Waist Hip Ratio (WHR)	0.2	1.0	1.9	1.4	1.1	-1.3	0.3
Number of treatments/medications taken	0.2	0.4	1.0	-0.7	-0.9	-0.0	-1.0
Average weekly spirits intake	0.2	0.3	0.6	-0.8	-0.3	0.6	0.6
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.5	-0.7	-0.5	0.5	0.3
Diabetes (mother)	0.2	0.3	1.0	1.0	0.1	-0.6	-0.2
Trunk fat percentage	0.2	1.0	2.2	-0.6	1.5	1.1	-1.0
Age when periods started (menarche)	0.2	0.4	1.1	-0.0	0.3	-1.0	-1.0
Multivitamins +/- minerals	0.2	0.3	0.9	-0.5	0.1	0.7	0.9
Past tobacco smoking	0.2	0.4	1.6	1.3	0.0	-0.7	0.2
Had other major operations	0.2	0.2	0.7	0.2	-0.8	-0.4	-0.0
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.2	1.0	0.1	-1.1	0.3
Medication: Ramipril	0.2	0.2	0.7	-0.5	-0.4	0.4	-0.8
Fluid intelligence score	0.2	0.4	1.1	-0.2	0.8	-0.6	-1.1
Trunk fat-free mass	0.2	0.9	4.2	2.0	0.1	-0.2	0.5
Hip circumference	0.2	0.7	2.4	-0.6	0.1	1.6	-0.9
Hair/balding pattern: Pattern 3	0.2	0.4	0.9	-0.2	-1.0	0.4	-0.8
Trunk predicted mass	0.2	0.9	4.2	2.0	-0.1	-0.2	0.5
Standing height	0.2	2.0	6.0	0.7	2.4	1.4	1.2
Hair/balding pattern: Pattern 4	0.2	0.6	1.4	1.0	0.7	-1.2	0.3
Loud music exposure frequency	0.2	0.2	0.9	0.0	0.1	0.5	1.0
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.9	0.2	0.5	-0.5	1.0
Body fat percentage	0.2	0.7	1.6	-0.4	1.2	0.8	-1.0
Arm fat-free mass (right)	0.2	1.1	5.1	2.3	0.0	-0.5	-0.1
Worry too long after embarrassment	0.2	0.3	0.7	0.2	-0.4	0.9	0.8
Number of children fathered	0.2	0.3	0.9	-0.3	0.4	1.0	0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.3	1.2	0.4	-0.1	-1.1	0.2
Emphysema/chronic bronchitis	0.2	0.3	0.8	-0.3	0.9	-0.6	0.2
Medication for pain relief, constipation, heartburn	0.2	0.3	0.9	-0.9	-0.2	0.6	-0.0
Medication: Seretide 50 evohaler	0.2	0.2	0.6	-0.8	0.2	-0.7	0.2
Arm predicted mass (right)	0.2	1.2	5.9	2.4	0.0	-0.5	0.2
Leg pain on walking	0.2	0.3	1.0	-1.0	0.3	-0.3	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	1.1	-0.0	0.0	0.0	1.1
Long-standing illness, disability or infirmity	0.2	0.3	1.0	1.0	0.4	0.6	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.5	-0.1	-0.7	0.6	-0.1
Osteoarthritis (self-reported)	0.2	0.2	0.4	-0.6	0.2	0.5	0.6
Average weekly champagne plus white wine intake	0.2	0.3	1.1	0.8	1.0	-0.2	-0.1
Mother’s age at death	0.2	0.3	0.6	-0.7	0.8	0.1	0.4
Commuting to job workplace: Public transport	0.2	0.2	0.7	0.6	0.8	0.0	0.1
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.5	-0.4	-0.7	-0.6	-0.2
Illnesses of father: High blood pressure	0.2	0.3	0.8	-0.8	-0.1	0.9	-0.0
Alcohol drinker status: Never	0.2	0.2	0.9	0.2	-0.9	-0.3	0.2
Ever smoked	0.2	0.4	1.0	-0.5	0.8	0.2	1.0
Arm fat-free mass (left)	0.2	1.0	4.8	2.2	-0.0	-0.3	0.5
Ever depressed for a whole week	0.2	0.3	0.7	0.6	-0.5	-0.3	-0.8
Heart disease (siblings)	0.2	0.3	1.2	-0.2	1.1	0.5	-0.0
Arm predicted mass (left)	0.2	1.3	5.7	2.4	0.2	-0.5	0.5
Bipolar Disorder (2018)	0.1	0.1	0.6	-0.7	-0.2	-0.1	0.3
Depressed Affect (Nagel 2018)	0.1	0.3	0.4	0.7	0.6	-0.5	0.4
Major Depression (MDD)	0.1	0.1	0.3	-0.0	0.2	0.1	0.6
Verbal and Numeric Reasoning (VNR)	0.1	0.1	0.6	0.2	0.8	0.3	0.1
HbA1C	0.1	0.1	0.2	-0.5	-0.2	0.2	0.1
Blood Platelet Count	0.1	0.8	1.7	1.1	0.8	-0.5	1.3
Heel T-Score	0.1	0.6	1.5	1.2	0.0	-1.1	0.6
Height	0.1	1.4	2.8	0.3	1.6	1.4	1.7
Systolic Blood Pressure	0.1	0.6	1.8	-0.7	-0.7	0.4	-1.3
Hair Pigment	0.1	1.8	5.9	1.0	0.0	-2.4	-1.5
Hand grip strength (left)	0.1	0.2	0.4	0.6	0.4	-0.1	0.6
Relative age of first facial hair	0.1	0.2	0.8	-0.9	0.2	0.0	-0.3
Medication: Co-codamol	0.1	0.1	0.3	0.3	-0.4	-0.1	0.5
Diabetes (father)	0.1	0.1	0.5	0.2	-0.3	0.7	-0.1
Leg fat-free mass (left)	0.1	0.7	2.1	1.4	0.7	0.8	0.3
Fed-up feelings	0.1	0.1	0.3	-0.4	-0.1	0.4	0.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.2	0.5	-0.3	-0.7	-0.3	-0.3
Sitting height	0.1	0.6	1.9	0.6	0.9	1.4	0.2
Leg predicted mass (left)	0.1	0.7	2.2	1.5	0.7	0.9	0.3
Trunk fat mass	0.1	0.6	1.7	0.2	1.3	0.8	-0.9
Waist circumference	0.1	0.3	0.9	0.6	0.2	0.2	-0.9
Number of incorrect matches in round	0.1	0.1	0.2	0.3	-0.5	-0.2	0.4
Nervous feelings	0.1	0.2	0.6	-0.2	0.7	0.4	0.1
Medication: Simvastatin	0.1	0.1	0.3	0.6	-0.1	-0.5	-0.2
Weight	0.1	0.3	0.7	0.8	0.4	0.8	-0.2
Arm fat percentage (right)	0.1	0.5	1.1	-0.6	0.9	1.0	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	0.3	0.4	0.5	-0.6	-0.4
Arm fat mass (right)	0.1	0.2	0.6	0.4	0.5	0.8	-0.2
Heart disease (mother)	0.1	0.2	0.4	0.5	0.3	-0.2	-0.6
Whole body fat mass	0.1	0.4	0.7	0.4	0.9	0.7	-0.7
Leg fat mass (right)	0.1	0.3	1.0	1.0	0.7	0.3	-0.4
Overall health rating	0.1	0.2	0.3	-0.5	-0.3	0.5	-0.5
Had major operations	0.1	0.1	0.3	0.3	-0.5	0.1	0.2
Whole body fat-free mass	0.1	0.8	3.8	1.9	0.3	0.2	0.5
Leg fat-free mass (right)	0.1	0.5	1.3	1.1	0.5	1.0	0.3
Arm fat percentage (left)	0.1	0.5	1.1	-0.6	0.8	1.1	-0.8
Qualifications: nursing, teaching	0.1	0.1	0.4	0.2	-0.3	0.6	0.4
Eye problems/disorders: Cataract	0.1	0.1	0.6	-0.3	-0.2	0.8	0.0
Whole body water mass	0.1	0.8	3.9	2.0	0.1	0.1	0.4
Leg predicted mass (right)	0.1	0.6	1.4	1.2	0.6	0.9	0.4
Arm fat mass (left)	0.1	0.2	0.7	0.2	0.5	0.9	-0.4
Number of self-reported non-cancer illnesses	0.1	0.2	0.4	-0.0	-0.2	0.6	0.6
Ever taken oral contraceptive pill	0.1	0.1	0.3	-0.1	0.3	-0.5	0.6
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.2	-0.2	0.0	-0.2	-0.4
Eye problems/disorders: Glaucoma	0.1	0.1	0.5	-0.2	0.3	-0.7	0.3
Basal metabolic rate	0.1	0.7	3.3	1.8	0.5	0.3	0.3
Leg fat mass (left)	0.1	0.2	0.6	0.8	0.5	0.5	-0.4
Blood Eosinophil Count	0.0	0.3	0.6	-0.8	0.3	-0.8	-0.6
Blood White Count	0.0	0.3	0.8	0.4	0.6	-0.5	0.9
BMI	0.0	0.3	0.5	-0.7	-0.6	0.5	-0.6
Smoking Status	0.0	0.1	0.4	-0.2	0.6	-0.3	0.2
Chronotype (morning person)	0.0	0.1	0.3	0.3	-0.5	0.3	0.1
Tanning	0.0	0.5	1.4	-1.2	-0.2	0.9	-0.7
Hand grip strength (right)	0.0	0.1	0.2	0.3	0.2	0.5	-0.1
Body mass index (BMI)	0.0	0.2	0.3	0.5	-0.6	0.2	-0.6
Ever unenthusiastic/disinterested for a whole week	0.0	0.0	0.1	-0.1	-0.2	-0.1	-0.3
Qualifications: O levels/GCSEs or equivalent	0.0	0.1	0.1	-0.3	0.3	0.4	0.3
Leg fat percentage (right)	0.0	0.1	0.5	0.3	0.3	-0.1	-0.7
Migraine (self-reported)	0.0	0.0	0.1	0.1	0.3	-0.1	0.3
Comparative height size at age 10	0.0	0.2	0.4	0.0	0.6	0.5	0.5
Knee pain experienced in last month	0.0	0.1	0.2	-0.4	0.1	-0.1	0.4
Leg fat percentage (left)	0.0	0.2	0.9	-0.1	0.0	0.1	-0.9

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