Hub : Genes

RBM45

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0320	0.0160	1.5e-02	-0.002	-0.001	-0.002	0.000	-0.002	7.6e-01	3.9e-01	8.5e-01	3.0e-01	9.1e-01
2	GTEx	Artery Aorta	0.1660	0.0570	6.5e-04	0.027	NA	0.060	NA	0.027	1.2e-02	NA	3.1e-04	NA	1.2e-02
3	GTEx	Testis	0.1650	0.0640	3.6e-03	0.007	NA	0.005	NA	0.008	1.5e-01	NA	1.8e-01	NA	1.3e-01
4	YFS	Blood	0.0503	0.0155	2.4e-09	0.040	0.040	0.036	0.039	0.038	5.6e-13	6.1e-13	6.0e-12	7.9e-13	1.5e-12
5	TCGA	Breast Invasive Carcinoma	0.0324	0.0168	1.1e-04	0.019	0.018	0.006	NA	0.016	6.0e-05	9.9e-05	1.5e-02	NA	2.6e-04
6	TCGA	Kidney Renal Clear Cell Carcinoma	0.0417	0.0224	1.4e-03	0.033	0.020	0.018	NA	0.032	1.2e-04	2.4e-03	3.9e-03	NA	1.5e-04
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0740	0.0390	2.4e-03	0.080	0.046	0.037	NA	0.003	2.5e-05	1.2e-03	3.5e-03	NA	2.0e-01
8	TCGA	Lung Squamous Cell Carcinoma	0.0728	0.0330	1.4e-04	0.030	0.029	0.028	NA	0.024	2.0e-04	2.9e-04	3.6e-04	NA	7.6e-04
9	TCGA	Thyroid Carcinoma	0.0560	0.0250	5.8e-05	0.035	0.036	0.020	NA	0.029	2.1e-04	2.0e-04	3.9e-03	NA	7.3e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.4	0.7	2.7	0.5	0.1	-1.6	0.7	-0.2	-0.3	-0.8	-1.3	0.4
Bipolar Disorder or Schizophrenia	0.7	1.6	6.5	-0.7	0.4	-0.6	-0.2	-1.0	-1.4	-1.8	-2.5	-0.9
Depressed Affect (Nagel 2018)	1.6	3.4	6.6	-2.3	-0.8	2.6	-1.3	-1.9	-2.0	-1.7	-1.1	-2.3
Depression (Nagel 2018)	1.6	2.4	3.8	-1.9	-1.6	1.2	-1.7	-1.3	-1.7	-1.7	-1.4	-1.3
Intelligence (Savage-Jansen 2018)	0.4	1.2	6.4	-0.6	-2.5	0.5	0.1	-1.4	-0.8	-0.0	-0.1	-1.0
Neuroticism (Nagel 2018)	0.9	2.2	11.0	-1.6	-0.6	3.3	-0.7	-0.9	-1.1	-1.1	-0.3	-1.3
Schizophrenia (2018)	0.8	1.8	5.0	-1.1	0.6	0.4	-0.8	-1.1	-1.6	-1.6	-2.2	-1.4
Schizophrenia vs Biploar Disorder	2.1	2.8	4.9	-1.9	-0.7	2.2	-1.3	-1.1	-2.2	-2.1	-1.5	-1.5
Worry (Nagel 2018)	0.4	0.9	6.4	-0.9	-0.2	2.5	-0.4	0.1	-0.4	-0.1	0.3	-0.5
Alzheimer’s Disease (in mother)	0.2	0.3	1.2	-0.9	-0.0	-0.1	1.1	-0.2	-0.1	-0.4	0.5	0.4
Alzheimer’s Disease (in father)	1.5	1.7	7.8	1.9	2.8	-0.8	-0.0	0.8	0.8	1.3	0.2	0.1
Alzheimer’s Disease (including proxy)	1.2	1.8	5.0	0.5	2.2	-1.9	1.5	0.8	1.1	0.8	1.2	1.0
Crohns Disease (2017)	0.7	1.6	4.2	-1.2	-0.6	1.8	-0.3	-2.1	-1.2	-1.2	-0.4	-1.3
Irritable Bowel Disease (IBD)	0.5	1.1	3.5	-0.3	-0.4	1.7	0.2	-1.9	-1.1	-1.0	-0.3	-0.8
Ulcerative Colitis (UC)	0.2	0.4	1.8	0.8	0.2	1.4	0.1	-0.9	-0.6	-0.3	-0.1	-0.4
Major Depression (MDD)	0.5	0.6	1.4	-0.2	-0.4	0.6	-0.5	-0.9	-1.1	-0.9	-0.9	-1.2
Reaction Time	1.6	3.1	6.9	-1.2	-0.5	1.1	-2.3	-1.4	-2.3	-2.6	-1.6	-1.8
Verbal and Numeric Reasoning (VNR)	0.2	0.5	1.6	0.2	-0.7	1.3	0.0	-0.9	0.1	0.9	0.5	-0.8
Breast Cancer	0.2	0.6	1.3	-0.5	-0.3	1.1	-0.8	0.3	-0.5	-1.2	-1.1	-0.2
Ovarian Cancer	1.1	1.5	6.1	-1.0	-0.9	1.0	2.5	0.5	0.9	0.3	1.6	0.7
Prostate Cancer	1.4	1.9	6.6	1.1	-0.2	0.2	0.1	1.9	1.9	2.6	0.4	1.4
Age at First Birth	2.0	2.8	6.6	-0.3	-0.4	-1.2	1.1	1.4	2.1	2.6	2.4	1.9
Bipolar Disorder (2011)	1.0	1.0	3.1	-0.2	-0.2	-1.0	-1.0	-0.1	-1.0	-1.6	-1.8	-0.4
Body Mass Index (BMI) (2010)	0.6	0.8	2.1	-1.1	0.3	-1.1	1.4	1.2	0.4	0.3	0.3	0.8
Coronary Artery Disease (CAD)	0.9	1.1	2.8	0.8	0.7	-1.7	0.1	1.3	0.9	0.9	1.0	1.2
Crohns Disease (2012)	1.0	1.7	4.0	-1.2	-0.7	1.3	-0.8	-2.0	-1.4	-1.2	-0.9	-1.4
Mean Putamen Volume	0.7	0.8	3.0	0.1	1.2	0.2	1.7	1.0	0.5	-0.3	0.3	1.1
Fasting Glucose	1.2	1.4	4.2	0.5	0.6	0.4	0.5	1.6	1.8	2.0	1.2	0.6
HbA1C	0.5	0.5	3.7	-0.6	0.1	1.9	-0.1	-0.5	-0.1	-0.4	0.4	-0.4
HDL Cholesterol	0.2	0.3	1.1	1.0	-0.3	-0.5	0.1	-0.8	0.1	0.1	0.6	0.3
LDL Cholesterol	0.4	0.6	3.5	-1.9	-0.8	0.8	0.1	-0.3	-0.0	-0.9	0.4	-0.2
Lupus	1.6	2.4	5.5	0.7	0.8	-1.2	2.0	0.4	1.8	2.4	2.3	1.1
Neuroticism (2016)	0.9	1.3	3.8	-0.8	-1.3	1.9	0.9	-1.4	-0.9	-0.4	-0.5	-1.1
Primary Biliary Cirrhosis	0.5	0.7	1.9	0.4	1.4	0.1	1.2	-0.1	0.6	0.1	1.3	0.7
Rheumatoid Arthritis	0.4	0.5	1.6	1.0	-0.3	-0.5	-0.1	-0.6	-0.9	0.2	-0.8	-1.2
Schizophrenia (2014)	0.7	1.6	4.6	-0.8	0.5	0.3	-0.8	-1.0	-1.6	-1.8	-2.1	-1.1
Triglycerides	1.2	1.9	4.4	-2.1	-0.7	1.7	-0.4	0.4	-1.3	-1.6	-2.0	-0.9
Type 2 Diabetes (T2D) (2012)	1.4	1.6	4.7	-0.4	2.2	-0.1	1.3	1.8	1.1	0.8	1.3	1.1
Ulcerative Colitis	0.3	0.4	1.3	1.1	0.6	1.0	-0.4	0.1	0.2	0.7	-0.1	0.1
Blood Eosinophil Count	0.2	1.6	6.0	-0.0	1.3	2.5	-1.5	-0.0	-0.6	-0.6	-1.3	-1.2
Blood Platelet Count	0.3	3.9	10.2	1.6	3.2	-1.6	0.6	2.4	2.0	1.6	1.5	2.1
Blood Red Count	0.1	0.8	3.4	-0.5	-0.3	-1.9	-0.9	-0.9	-0.3	0.5	0.2	-1.2
Blood White Count	0.3	2.4	4.9	-2.1	-0.3	-0.8	-1.3	-1.3	-1.7	-1.8	-2.2	-1.5
Heel T-Score	0.1	0.7	3.2	0.4	-1.4	1.8	-0.4	-0.4	-0.3	-0.1	-0.4	-0.4
BMI	0.3	1.5	10.3	0.8	0.2	-3.2	0.3	0.3	1.1	0.8	0.7	0.5
Height	0.7	12.8	47.5	2.9	-2.4	-1.4	6.9	0.6	4.2	4.7	2.6	2.4
Waist Hip Ratio (WHR)	0.1	0.5	1.8	-1.3	-0.6	-0.7	1.3	0.4	0.1	-0.3	0.2	-0.3
Systolic Blood Pressure	1.0	5.0	17.9	0.4	4.2	-1.2	-0.0	2.8	2.8	2.7	1.0	1.2
Smoking Status	4.2	10.1	19.4	-3.3	-1.6	1.9	-2.9	-2.5	-3.6	-3.1	-4.1	-4.4
Allergy or Eczema	0.4	1.0	4.9	0.3	2.2	0.4	-1.0	-0.8	-0.3	-0.3	1.3	0.0
Cardiovascular Disease	0.5	1.7	5.4	-0.1	2.3	0.4	1.1	1.6	1.5	1.7	0.5	0.7
Hypothyroidism (self reported)	0.2	0.4	1.0	-1.0	-0.7	-0.0	-0.4	0.8	-0.5	-0.8	-0.0	0.4
Respiratory disease	0.8	1.7	4.8	0.2	2.2	-1.3	0.7	0.7	1.4	1.0	1.9	1.2
Type 2 Diabetes (T2D) (2018)	0.6	1.1	4.0	-0.5	-2.0	0.8	1.3	-1.1	-0.6	-0.7	-1.1	-0.3
Lung FEV1/FVC ratio	0.2	0.8	4.8	-0.5	-0.5	-2.2	-0.4	0.6	-0.0	-0.2	-1.3	0.3
Lung FVC	0.6	3.1	23.1	0.6	1.2	4.8	0.1	-0.3	-0.2	-0.6	-1.3	-0.7
Neuroticism	1.8	4.3	9.9	-2.3	-1.4	3.1	-1.2	-2.3	-2.0	-1.8	-1.3	-2.4
Chronotype (morning person)	0.8	1.8	3.4	1.0	0.8	-0.6	1.6	1.0	1.8	1.4	1.7	1.5
Hair Pigment	0.2	4.3	12.9	3.6	0.9	-2.5	0.9	1.7	2.1	1.5	1.8	2.4
Tanning	0.1	1.6	3.6	0.7	0.9	-0.4	-1.2	-1.9	-1.9	-1.4	-0.8	-1.4
Hand grip strength (left)	0.8	2.0	3.5	-1.6	-1.5	1.9	0.7	-1.5	-1.6	-1.4	-0.8	-1.5
Number of treatments/medications taken	0.2	0.3	1.1	-0.9	0.1	0.2	0.1	-0.2	-0.6	-0.3	-1.0	-0.8
Average weekly spirits intake	1.0	1.3	5.5	-0.8	-0.9	2.3	-1.3	-0.2	-0.8	0.6	-0.2	-1.3
Sensitivity / hurt feelings	0.5	0.8	4.5	-1.3	-0.6	2.1	0.4	0.4	-0.5	-0.5	0.0	-0.4
Frequency of depressed mood in last 2 weeks	0.6	0.9	4.5	-2.1	-1.1	0.9	-0.9	0.2	-0.5	-0.3	-0.3	-0.3
Hearing difficulty/problems: Yes	0.9	1.4	6.9	1.1	0.6	-2.6	1.5	-0.9	0.8	0.3	0.7	0.5
Relative age of first facial hair	0.7	1.4	3.6	1.9	-0.8	-0.9	1.0	1.2	0.9	0.7	1.2	1.5
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	2.5	-0.1	-0.0	-0.2	-1.6	-0.1	-0.1	0.5	0.1	-0.5
Ever used hormone-replacement therapy (HRT)	0.6	0.8	3.2	-0.9	0.3	0.1	-0.1	-1.1	-1.3	-1.8	-0.4	-0.2
Ever had hysterectomy (womb removed)	0.5	0.5	2.0	-0.1	1.4	0.3	-1.0	-0.6	-0.6	-0.6	-0.5	-0.6
Systolic blood pressure, automated reading	0.4	1.1	5.2	0.2	2.3	-1.4	-1.3	-0.1	0.3	0.4	-0.6	-0.5
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	2.5	-0.2	-0.9	-0.1	1.6	-0.6	0.4	-0.0	-0.0	0.3
Angina	0.4	0.5	1.2	-0.6	-0.5	0.2	-0.7	-0.7	-1.1	-1.1	0.1	-0.6
Medication for hormone replacement therapy	0.9	1.0	2.0	1.1	0.5	0.5	1.2	0.0	1.2	1.3	1.4	0.5
Vitamin and mineral supplements	0.3	0.4	1.1	0.4	1.1	0.3	-0.3	-1.0	-0.3	-0.5	0.0	-0.6
Supplements: Zinc	0.9	1.0	2.0	-1.1	-1.3	-0.3	-0.2	-1.0	-1.2	-1.4	-0.9	-0.8
Medication: Co-codamol	0.4	0.4	1.2	-0.1	0.4	-0.4	0.2	-1.1	-0.6	-0.7	-1.1	-0.7
Medication: Metformin	0.8	1.1	3.6	-0.8	-1.9	1.0	1.8	-0.9	-0.4	-0.7	-0.6	0.0
Diabetes (father)	0.5	0.6	1.5	-0.8	-1.2	-1.0	1.0	0.6	0.5	0.1	-0.4	0.7
Diabetes (mother)	2.3	2.9	6.6	-0.5	0.7	-1.0	0.7	2.6	2.5	2.4	1.4	1.8
Severe depression (siblings)	0.5	0.6	3.1	0.7	1.1	1.8	-0.6	0.5	0.1	-0.3	0.1	0.2
Pack years adult smoking proportion	0.2	0.3	1.0	-0.1	1.0	0.3	0.4	-0.8	-0.1	-0.8	-0.3	0.1
Impedance of leg (right)	0.2	1.1	3.7	-1.9	-1.4	1.0	0.7	-0.3	-1.0	-0.9	-0.0	-0.8
Leg fat-free mass (left)	1.4	7.2	12.7	3.0	0.8	-2.6	2.7	1.6	3.6	3.4	2.4	2.8
Trunk fat percentage	0.5	2.0	11.6	0.9	-0.8	-3.4	1.1	-0.1	0.9	1.2	1.1	0.7
Hand grip strength (right)	0.2	0.5	1.6	-1.3	0.2	1.1	1.0	-0.6	-0.3	-0.3	0.2	-0.5
Townsend deprivation index at recruitment	0.4	0.5	2.0	-1.1	-1.4	0.1	-0.2	-0.6	-0.6	-0.5	-0.1	-0.7
Current tobacco smoking	2.3	3.7	10.6	-1.0	-1.5	1.1	-1.9	-1.5	-2.1	-1.4	-3.3	-2.5
Average weekly fortified wine intake	0.3	0.3	1.0	-0.4	0.8	0.3	-0.9	-1.0	-0.5	-0.2	0.1	-0.5
Maternal smoking around birth	0.4	0.5	1.4	0.5	0.6	-0.2	1.2	0.6	1.0	0.5	0.8	0.5
Fed-up feelings	2.2	4.0	7.3	-2.7	-2.0	2.5	-1.0	-1.6	-2.0	-1.6	-1.4	-2.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	4.6	-2.1	-1.4	1.1	-1.1	0.0	-0.8	-1.0	-1.3	-0.6
Relative age voice broke	0.3	0.4	0.9	0.9	-0.7	0.6	-0.0	0.9	0.5	0.1	0.7	1.0
Taking other prescription medications	0.2	0.2	1.2	-0.5	-0.4	-0.5	1.1	-0.1	-0.1	-0.5	0.3	-0.0
Age when periods started (menarche)	0.3	0.6	2.0	-1.0	0.5	1.4	0.6	-0.2	-0.0	-0.6	1.0	-0.6
Bilateral oophorectomy (both ovaries removed)	2.5	2.8	6.3	-0.5	1.3	1.6	-2.5	-1.2	-2.2	-2.0	-1.7	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	3.8	1.9	-0.1	-0.3	-0.8	0.1	0.2	0.3	0.9	0.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.4	-1.2	-0.3	0.6	0.0	-0.1	-0.1	-0.3	-0.0	-0.3
Qualifications: CSEs or equivalent	1.6	2.1	3.9	0.9	0.3	0.3	2.0	1.5	1.9	1.5	1.9	1.5
Serious illness, injury or assault to yourself	2.0	2.5	3.9	-0.5	-1.8	-1.5	-0.9	-1.8	-1.9	-1.8	-2.0	-1.3
High blood pressure	0.3	0.9	3.3	-1.0	1.8	-1.6	0.9	0.2	0.2	0.4	-0.3	0.2
Hayfever, allergic rhinitis or eczema	0.2	0.5	2.2	-0.3	1.5	0.7	-0.5	-0.8	-0.2	-0.4	0.8	-0.2
Multivitamins +/- minerals	1.0	1.2	3.5	0.6	-0.8	-0.5	1.3	1.9	1.0	0.8	0.2	1.8
Stomach or abdominal pain in last month	0.8	1.0	6.0	-0.4	-0.1	-2.4	1.4	-0.3	0.2	0.3	0.7	0.4
Supplements: Glucosamine	2.0	2.6	5.5	-2.3	-1.8	0.6	-0.9	-0.8	-1.9	-2.0	-2.1	-1.0
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.9	0.5	-1.0	-0.6	-0.6	-0.3	-0.6	-0.5	-0.8	-0.6
Medication: Atenolol	0.2	0.3	1.0	0.3	-0.1	1.0	-0.2	-0.5	0.1	0.8	0.3	-0.6
Medication: Levothyroxine sodium	0.3	0.5	1.8	0.0	0.0	-1.3	0.8	0.9	0.6	0.3	0.6	0.7
Sitting height	0.9	6.7	15.6	2.1	0.1	0.6	3.3	1.1	4.0	3.4	2.9	2.9
Chronic bronchitis/emphysema (father)	0.3	0.3	1.2	1.1	0.8	0.4	0.0	0.5	0.4	0.3	0.3	0.4
High blood pressure (mother)	0.5	0.7	2.9	1.1	0.0	0.6	-0.5	0.6	1.0	1.7	0.2	-0.1
Body mass index (BMI)	0.8	3.5	16.7	1.6	0.6	-4.1	0.9	0.4	1.8	1.5	1.6	1.6
Impedance of leg (left)	0.3	1.2	4.7	-2.2	-1.4	0.5	0.6	-0.6	-1.2	-1.0	0.1	-1.0
Leg predicted mass (left)	1.4	7.5	13.2	3.1	0.8	-2.6	2.7	1.7	3.6	3.5	2.5	2.9
Trunk fat mass	0.8	3.5	14.2	1.3	-0.5	-3.8	2.0	0.3	1.8	1.9	1.7	1.3
Waist circumference	1.3	4.7	16.0	1.7	-0.1	-4.0	2.5	1.0	2.3	1.9	2.0	1.9
Number of incorrect matches in round	0.6	1.1	3.5	0.4	1.9	-0.1	-0.2	1.2	1.2	1.0	1.4	0.4
Past tobacco smoking	1.4	2.5	6.3	1.9	0.5	0.2	1.4	1.1	1.7	1.8	1.7	2.5
Alcohol usually taken with meals	0.5	0.8	3.4	-0.6	-0.3	0.8	-1.9	0.6	-0.2	0.0	-1.2	-0.6
Nervous feelings	0.7	1.3	7.3	-1.7	-0.3	2.7	-0.5	0.5	-0.1	0.6	0.4	-0.6
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.5	4.9	-1.2	-1.6	2.2	-1.5	-0.4	-0.7	-0.0	-0.7	-1.2
Hearing difficulty/problems with background noise	1.5	2.5	3.8	-1.8	-1.2	-1.5	0.9	-1.9	-1.4	-2.0	-1.7	-1.4
Hair/balding pattern: Pattern 2	1.3	1.7	7.2	1.4	0.3	-0.7	2.7	0.5	1.0	0.2	1.3	1.6
Had menopause	1.8	2.3	5.0	0.5	-0.2	2.2	-1.7	-0.9	-1.8	-1.7	-2.0	-1.3
Had other major operations	1.3	1.5	4.0	-0.7	-0.6	-1.3	-2.0	-0.4	-1.3	-2.0	-1.1	-0.5
Forced vital capacity (FVC)	0.8	2.9	5.7	1.4	1.4	2.1	2.0	1.5	2.4	2.0	0.9	1.3
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	3.5	1.6	-0.1	-0.1	-1.9	-0.5	-0.6	-0.4	-0.2	-0.0
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	3.8	1.1	1.3	1.9	-0.2	-0.5	-0.4	-1.0	-0.5	-0.1
Qualifications: None of the above	0.5	1.1	1.9	-1.3	0.3	-1.1	-1.3	-1.1	-1.0	-0.8	-0.7	-1.4
Financial difficulties in last 2 years	0.5	0.6	3.0	0.7	0.7	-1.7	0.4	0.4	0.2	-0.3	0.6	0.9
Mouth/teeth dental problems	1.7	2.6	5.1	1.6	1.6	0.6	0.0	2.2	1.6	2.2	1.6	1.6
Heart attack	0.3	0.4	2.0	0.5	-1.4	0.0	0.3	0.7	0.3	0.8	0.3	0.4
Allergy	0.1	0.3	1.4	0.2	-1.2	-0.1	-0.0	0.2	-0.3	-0.1	-0.9	-0.4
Pain all over the body in last month	1.6	1.7	3.4	0.7	-0.1	-1.8	1.4	0.5	1.1	1.5	1.8	1.5
Diabetes (self-reported)	0.5	0.7	2.6	-0.8	-1.6	1.2	1.1	0.1	0.4	0.2	-0.3	0.5
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	1.3	-0.2	-0.2	1.1	-0.7	-0.1	-0.7	-0.8	-0.2	-0.1
Medication: Ramipril	0.7	0.9	3.1	0.2	1.2	0.9	-0.7	1.8	-0.2	0.0	-1.4	-0.2
Medication: Simvastatin	0.7	1.0	5.3	-1.1	-1.2	2.3	0.2	-0.0	-0.3	-0.1	-0.9	-0.3
Fluid intelligence score	0.4	0.8	4.6	0.6	-0.8	2.1	0.0	-0.0	0.6	1.0	0.2	-0.6
Illnesses of siblings	0.2	0.2	0.6	-0.4	-0.6	-0.3	0.6	0.1	-0.8	-0.7	-0.1	0.0
Neuroticism score	1.7	3.5	11.0	-2.2	-2.1	3.3	-0.9	-1.4	-1.6	-1.1	-0.9	-2.0
Weight	1.5	7.1	15.7	2.3	-0.0	-4.0	3.0	0.9	3.2	2.9	2.7	2.7
Impedance of arm (right)	0.2	0.9	2.2	-0.2	-1.5	1.5	0.4	-0.8	-1.1	-0.4	-0.4	-1.2
Arm fat percentage (right)	0.5	2.0	14.2	0.9	-0.3	-3.8	0.8	-0.2	0.7	0.9	0.8	0.6
Trunk fat-free mass	1.2	7.2	14.1	2.2	1.0	-1.9	3.6	1.6	3.8	3.2	2.6	2.9
Hip circumference	1.0	4.5	10.8	2.6	0.4	-3.3	1.7	1.2	2.4	2.0	1.7	2.2
Time employed in main current job	0.4	0.5	1.4	1.2	0.7	0.5	0.2	0.1	0.7	0.4	0.8	0.9
Alcohol intake versus 10 years previously	0.4	0.6	2.0	-0.9	-1.4	-1.3	0.4	-0.1	-0.6	-0.0	-0.8	-0.5
Father’s age at death	0.2	0.3	0.9	0.9	-0.4	0.9	0.1	-0.2	0.1	0.5	0.8	-0.4
Worrier / anxious feelings	1.3	2.4	7.0	-2.6	-2.3	2.6	0.4	-0.6	-0.8	-0.5	-0.3	-1.0
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	7.3	-2.7	-1.8	-0.8	1.9	-0.4	-0.2	-1.1	0.1	0.3
Falls in the last year	0.5	0.6	2.2	0.1	-0.8	-1.5	0.3	0.0	0.6	0.8	1.1	0.5
Hair/balding pattern: Pattern 3	0.2	0.3	0.9	0.8	-0.1	-0.0	0.5	-0.5	0.4	0.8	0.9	0.1
Number of live births	0.6	0.8	1.7	1.0	1.1	-0.4	0.3	1.3	1.1	0.2	0.4	1.2
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	4.5	1.0	1.0	1.1	1.7	1.5	2.1	1.7	0.5	1.4
Pulse rate	1.2	2.1	12.1	3.5	1.0	-1.5	1.3	-0.2	0.8	0.9	0.4	0.5
Happiness	0.9	1.1	3.3	-0.3	-0.6	1.8	0.1	-1.2	-1.0	-1.6	-0.4	-0.7
Noisy workplace	0.2	0.2	0.7	-0.8	0.1	-0.2	0.8	-0.6	-0.1	-0.5	-0.4	-0.1
Qualifications: A levels/AS levels or equivalent	1.0	2.2	4.4	1.7	1.7	0.9	-0.4	2.0	1.7	2.1	1.0	0.8
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.3	1.3	0.3	0.2	0.7	1.1	1.5	1.0	0.7	1.1
Mouth/teeth dental problems: Dentures	1.7	2.9	6.0	-1.1	-2.1	-0.7	-0.9	-1.4	-1.8	-2.3	-2.5	-1.6
Asthma	1.5	2.9	6.2	1.4	2.5	-1.4	0.9	1.5	2.1	1.8	1.7	1.6
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	3.0	-0.4	-0.7	1.3	0.7	-1.2	-1.2	-1.7	-0.9	-0.9
Medication: Cholesterol lowering	0.5	0.7	2.0	-1.4	-1.4	1.1	-0.1	-0.3	-0.6	-0.0	-0.5	-0.7
Depression (self-reported)	0.8	0.9	4.0	0.0	2.0	-0.3	0.1	0.1	0.9	0.7	1.5	0.9
Medication: Lansoprazole	0.8	0.9	1.7	-0.7	1.1	0.6	-0.3	-1.3	-1.2	-1.1	-0.3	-1.1
Prospective memory result	0.8	1.0	2.1	-0.1	-0.8	-0.1	-1.4	-0.8	-1.3	-1.4	-1.2	-0.6
Lung cancer (father)	1.1	1.3	6.6	-0.9	-0.1	-0.5	2.6	-0.3	0.7	0.5	1.7	0.8
Illnesses of mother	2.2	2.7	6.3	-0.0	-1.7	0.2	-0.6	-2.5	-2.3	-1.9	-1.6	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.2	4.9	1.3	0.7	0.9	2.0	1.5	2.2	1.9	0.4	1.2
Pulse wave Arterial Stiffness index	0.4	0.4	1.2	0.4	-0.9	0.7	0.7	-0.4	-0.3	0.0	-0.7	-1.1
Impedance of arm (left)	0.2	1.1	5.3	-0.5	-1.4	2.3	-0.0	-0.4	-0.9	-0.1	-0.5	-1.3
Arm fat mass (right)	0.8	3.4	16.6	1.4	-0.3	-4.1	1.6	0.2	1.6	1.7	1.3	1.3
Trunk predicted mass	1.4	7.8	14.8	2.3	1.0	-2.1	3.7	1.6	3.9	3.3	2.7	3.1
Standing height	0.7	7.3	23.6	1.8	-1.0	-0.2	4.9	1.1	3.5	3.4	2.6	2.4
Length of working week for main job	0.4	0.5	3.1	-0.1	1.8	-0.8	0.4	0.1	0.7	0.1	-0.2	0.1
Exposure to tobacco smoke at home	1.0	1.1	4.2	-0.3	1.7	-0.4	2.0	-0.3	0.7	0.3	1.4	0.6
Breastfed as a baby	0.6	0.8	2.8	1.7	0.7	0.8	0.2	0.1	-0.6	-0.9	-1.4	-0.1
Tense / ‘highly strung’	0.3	0.4	2.6	-0.7	0.1	1.6	-0.6	-0.0	-0.4	-0.2	-0.1	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	5.8	-0.3	0.6	0.4	2.4	-0.2	0.8	0.0	1.8	0.9
Hair/balding pattern: Pattern 4	0.4	1.0	5.2	0.3	1.1	0.5	-2.3	1.2	0.1	-0.3	-0.2	0.5
Birth weight of first child	1.3	2.3	4.9	0.8	1.7	0.7	0.3	1.4	2.1	2.2	1.8	1.4
Peak expiratory flow (PEF)	0.8	1.7	3.8	-0.2	0.6	0.4	1.7	1.7	2.0	1.6	0.8	1.6
Pulse wave reflection index	0.5	0.7	1.2	-1.1	-0.8	1.1	1.1	0.8	0.6	0.8	0.3	-0.4
Ever highly irritable/argumentative for 2 days	0.4	0.4	2.8	-1.7	0.6	0.4	0.3	0.1	-0.1	-0.6	0.2	0.3
Loud music exposure frequency	3.1	3.4	5.4	2.2	1.5	-2.3	1.7	1.2	2.1	1.3	1.9	1.9
Qualifications: O levels/GCSEs or equivalent	1.5	2.3	7.1	2.7	1.1	0.1	1.0	1.0	1.6	1.6	1.8	1.7
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	3.7	-0.1	-0.8	-1.1	1.9	-0.7	0.4	-0.0	0.6	0.2
Blood clot in the leg (DVT)	0.2	0.3	0.9	0.8	-1.0	-0.3	-0.7	-0.1	-0.1	-0.3	-0.5	-0.4
Medication: Paracetamol	0.5	0.9	2.6	-1.6	1.1	0.5	0.2	-0.5	-1.0	-1.6	-0.2	-0.3
Headache pain in last month	1.0	1.7	4.9	-1.5	0.1	0.5	-1.0	-1.3	-2.0	-2.2	-1.1	-0.8
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.3	1.5	1.1	-0.0	0.3	0.4	0.8	0.1	0.9	0.9
Glaucoma (self-reported)	0.7	0.8	2.3	1.2	0.3	-0.5	0.7	1.0	1.1	1.5	0.7	0.5
Gout (self-reported)	0.8	1.1	6.2	-2.5	-0.6	-0.0	0.9	-1.0	-0.6	-0.6	-0.3	-1.0
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.2	-0.3	-0.3	-0.2	-0.2	1.1	0.3	0.1	0.3	0.7
Medication: Amlodipine	0.4	0.5	1.8	0.5	0.6	-0.7	-0.5	1.4	0.5	1.0	0.1	0.6
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.8	0.4	1.1	0.0	1.3	0.8	1.7	1.7	1.0	1.1
Birth weight	0.4	0.8	4.2	-2.1	-1.2	0.4	-0.0	0.8	0.2	-0.3	-0.8	-0.2
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.0	-1.1	1.4	-0.4	-1.0	0.2	0.2	0.0	1.1	0.5
High blood pressure (siblings)	0.3	0.5	1.8	-0.0	0.7	1.2	-1.4	0.3	0.2	0.5	0.1	-0.6
Forced vital capacity (FVC), Best measure	0.9	3.4	7.1	1.8	1.0	1.5	2.3	1.9	2.7	2.1	1.1	1.7
Body fat percentage	0.7	2.7	16.6	0.9	-0.5	-4.1	1.4	-0.1	1.0	1.1	1.4	0.9
Leg fat percentage (right)	0.7	2.5	16.7	0.4	-0.5	-4.1	1.0	0.1	0.9	1.0	1.2	0.8
Arm fat-free mass (right)	1.1	5.6	10.8	1.8	0.9	-2.3	2.7	1.6	3.3	2.8	2.3	2.7
Exposure to tobacco smoke outside home	0.8	1.1	7.0	-0.2	-0.5	-0.6	2.6	-0.5	-0.3	-0.9	0.7	0.6
Comparative body size at age 10	0.3	0.7	1.5	-1.2	0.6	0.4	-1.0	-0.5	-0.9	-1.0	-0.9	-0.9
Number of full brothers	2.7	3.4	7.7	2.8	1.7	-1.3	1.6	1.0	2.2	1.4	1.8	2.2
Worry too long after embarrassment	0.5	0.9	6.0	0.9	-0.1	2.5	0.1	-0.4	0.1	-0.2	1.0	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.5	2.0	7.5	-0.4	0.3	1.0	-0.2	-1.8	-1.7	-2.7	-1.4	-0.9
Wheeze or whistling in the chest in last year	0.2	0.4	1.9	-0.6	0.2	-0.7	0.3	-1.4	-0.7	-0.6	-0.2	-0.4
Number of children fathered	0.5	0.6	2.4	0.8	1.0	1.6	-0.2	0.4	-0.4	-0.9	0.1	0.3
Reason for reducing amount of alcohol drunk: Health precaution	1.5	1.8	9.5	-3.1	-0.2	0.6	-0.5	-0.9	-1.4	-1.1	-0.6	-1.1
Age at first live birth	0.7	1.2	2.3	-0.8	-0.2	0.7	1.5	0.9	1.4	1.2	1.3	1.0
Pulse wave peak to peak time	0.4	0.5	1.6	-0.3	0.8	-0.8	-0.5	0.5	0.5	0.1	0.9	1.3
Health satisfaction	0.5	0.6	2.8	0.5	-0.1	-0.2	1.7	-1.1	-0.2	-0.9	-0.3	-0.0
Shortness of breath walking on level ground	3.5	4.1	6.4	-2.5	-2.5	0.2	-1.2	-1.9	-2.1	-2.3	-2.4	-2.0
Qualifications: College or University degree	0.4	1.2	4.0	1.4	0.3	0.4	0.2	1.3	1.4	2.0	0.9	0.8
Eye problems/disorders: None of the above	0.7	0.9	2.8	-0.8	-0.8	0.1	-1.5	0.9	-0.4	-0.5	-1.7	0.2
Mouth/teeth dental problems: Loose teeth	1.0	1.2	2.6	-1.6	0.4	0.8	-1.6	-0.3	-1.3	-1.4	-0.6	-0.5
Emphysema/chronic bronchitis	0.2	0.3	0.7	-0.5	-0.6	0.9	0.0	-0.8	-0.3	-0.2	0.3	-0.2
Medication for pain relief, constipation, heartburn	1.6	2.6	5.5	1.8	0.1	-1.3	0.1	1.8	2.2	2.3	1.6	1.7
Neck or shoulder pain in last month	0.7	1.0	5.4	-0.6	2.3	-1.5	0.1	-0.1	-0.1	-0.9	-0.4	0.1
Medication: Blood pressure	0.2	0.3	1.0	-0.7	0.5	-1.0	-0.3	0.2	-0.0	0.7	-0.5	-0.5
Angina (self-reported)	0.2	0.3	0.8	-0.4	-0.4	0.3	-0.2	-0.4	-0.9	-0.9	0.0	-0.3
Migraine (self-reported)	0.4	0.5	1.9	-0.1	0.9	-1.4	-0.6	0.2	-0.0	-0.1	0.9	0.9
Medication: Ibuprofen	1.5	1.8	4.2	-0.4	-0.1	1.4	-0.0	-1.9	-1.5	-2.1	-1.3	-1.5
Medication: Allopurinol	1.3	1.8	4.0	-0.5	2.0	-1.6	1.4	1.0	1.3	0.7	1.3	1.4
Medication: Omeprazole	0.9	1.1	4.2	-1.2	-0.5	-1.1	2.0	-0.2	0.4	0.5	1.4	0.4
Medication: Seretide 50 evohaler	0.5	0.6	2.9	0.6	0.9	-0.2	1.7	-0.0	0.5	0.3	0.4	0.7
Mean time to correctly identify matches	4.0	7.6	14.8	-1.9	-1.3	1.6	-3.2	-2.5	-3.6	-3.9	-2.7	-3.0
Heart disease (mother)	3.3	4.0	11.3	0.4	1.5	-1.1	-0.1	3.4	2.5	2.7	1.2	2.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.5	-0.3	0.3	0.3	-1.2	-0.6	-0.9	-1.1	-0.1	-0.4
Whole body fat mass	1.1	4.5	19.1	1.6	-0.3	-4.4	2.2	0.6	2.0	2.0	1.7	1.7
Leg fat mass (right)	1.2	4.5	20.2	1.4	-0.2	-4.5	2.3	0.5	2.0	1.9	1.7	1.6
Arm predicted mass (right)	1.1	5.7	11.1	1.7	0.8	-2.5	2.8	1.6	3.3	2.8	2.2	2.7
Pulse rate, automated reading	2.5	8.2	33.1	5.8	3.4	-4.1	0.8	0.5	1.8	1.7	1.6	1.8
Alcohol intake frequency.	0.2	0.4	1.7	0.2	-0.9	-1.3	-0.4	0.3	-0.1	0.1	-0.5	0.3
Comparative height size at age 10	0.5	2.7	8.4	1.2	-0.5	-0.8	2.2	0.5	2.3	2.9	1.4	1.2
Number of full sisters	3.2	3.8	7.8	1.6	1.0	-2.8	2.5	1.3	2.0	1.8	1.5	2.3
Suffer from ‘nerves’	0.5	0.8	2.8	0.6	-0.1	1.2	-0.7	1.1	0.8	1.7	0.6	-0.4
Overall health rating	0.3	0.7	2.6	-1.4	-1.6	-0.4	0.7	-0.2	-0.5	-0.8	-0.5	0.3
Chest pain or discomfort	0.3	0.4	1.2	-1.0	0.0	-0.3	-0.0	-0.9	-0.6	-1.1	0.1	-0.1
Had major operations	0.4	0.4	1.7	0.3	1.0	-1.3	-0.6	0.2	0.2	0.3	0.5	0.2
Age at last live birth	0.2	0.3	0.7	-0.8	-0.2	0.4	0.7	0.6	0.7	0.4	0.8	0.2
Family relationship satisfaction	0.2	0.3	0.9	-0.0	0.1	0.1	0.6	-0.2	-0.0	-0.8	0.9	0.7
Leg pain on walking	0.2	0.3	1.6	-1.3	-0.2	-0.1	0.4	0.1	-0.4	-0.6	-0.6	-0.2
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	3.8	0.7	0.5	-0.6	0.9	1.9	1.5	1.8	0.5	1.1
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.7	-0.8	0.8	0.6	-1.0	0.1	-0.6	-1.3	-0.9	-0.0
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.8	0.1	1.2	1.7	0.4	-0.1	0.1	0.5	-0.1	-0.5
Medication: Aspirin	1.2	1.5	3.3	-0.5	-0.6	1.0	-1.4	-0.9	-1.8	-0.9	-1.6	-1.6
Supplements: Vitamin C	0.5	0.6	1.2	-1.1	-0.9	-0.3	0.0	-0.4	-1.0	-0.9	-0.8	-0.9
Knee pain experienced in last month	0.1	0.1	0.5	0.0	0.7	0.4	-0.4	0.2	0.4	0.0	0.1	0.4
Hypertension (Self-reported)	0.4	1.0	4.2	-0.3	2.1	-1.4	1.0	0.6	0.6	0.7	0.0	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.9	3.5	-1.0	-0.4	-0.3	1.9	-1.1	-0.5	-1.0	0.7	-0.0
Illnesses of father: Heart disease	1.7	2.3	5.1	-1.4	-0.7	-0.3	-0.6	-1.8	-2.2	-1.1	-2.3	-1.9
Illnesses of siblings: Diabetes	0.5	0.6	2.8	0.1	-0.1	-1.7	1.1	0.1	0.8	0.1	0.4	0.9
Smoking status: Previous	0.8	1.2	3.4	-1.8	-0.1	-0.5	-1.0	-0.5	-0.9	-1.4	-0.7	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	2.4	5.1	12.6	2.2	0.2	-0.7	3.5	1.3	2.8	2.8	2.5	2.0
Whole body fat-free mass	1.3	7.5	13.8	2.5	0.8	-2.4	3.3	1.5	3.7	3.3	2.7	3.0
Leg fat-free mass (right)	1.2	6.4	11.6	2.8	0.7	-2.5	2.5	1.4	3.4	3.3	2.4	2.6
Arm fat percentage (left)	0.6	2.5	13.8	1.2	-0.1	-3.7	0.9	0.3	1.2	1.5	1.2	0.9
Average weekly red wine intake	0.4	0.5	3.3	-0.3	0.4	-0.3	-1.8	-0.1	-0.2	0.4	-0.6	-0.8
Handedness (chirality/laterality): Left-handed	0.3	0.4	1.1	-0.8	-0.5	-1.1	0.2	0.6	0.3	0.6	0.5	0.5
Mood swings	0.3	0.5	1.5	-1.2	-1.2	1.0	0.1	0.2	0.1	0.2	0.8	-0.2
Loneliness, isolation	0.2	0.3	1.3	-0.2	-0.7	1.1	-0.1	0.2	0.3	0.9	0.3	0.3
Long-standing illness, disability or infirmity	0.2	0.4	1.3	-0.9	-0.4	-1.2	0.4	0.1	0.0	-0.2	-0.7	0.6
Ever had bowel cancer screening	1.1	1.3	2.6	-1.6	-1.6	0.3	0.7	-1.1	-1.3	-1.4	-0.3	-1.1
Diabetes diagnosed by doctor	0.7	1.1	5.1	-0.6	-2.3	0.8	1.6	-0.6	0.0	-0.2	-0.8	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.9	-0.6	0.2	-0.6	0.9	0.6	0.2	0.7	-0.2	-0.7
Friendships satisfaction	0.7	0.9	2.5	1.3	0.9	-0.2	1.6	-0.1	0.1	-1.4	-0.5	1.0
Qualifications: nursing, teaching	0.4	0.6	3.1	0.9	0.4	1.8	-0.6	0.5	0.3	0.4	0.1	0.2
Commuting to job workplace: Walk	0.4	0.4	1.4	1.2	0.2	0.4	0.7	0.2	0.7	1.1	0.3	-0.1
Eye problems/disorders: Cataract	1.4	1.6	6.4	0.9	1.0	0.8	1.7	-0.2	0.9	1.3	2.5	0.4
Mouth/teeth dental problems: Mouth ulcers	1.0	1.6	3.3	0.6	1.1	-0.3	1.5	0.8	1.8	1.2	1.7	1.6
Medication for cholesterol	2.6	4.0	5.7	-2.2	-2.2	1.1	-2.0	-1.4	-2.2	-2.0	-2.4	-2.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	4.2	0.1	-0.8	2.1	-0.4	0.2	-0.6	-0.7	-1.3	-0.9
Back pain experienced in last month	0.6	0.9	1.5	-1.2	1.1	-0.2	-1.0	-0.8	-0.6	-0.6	-1.0	-1.2
Mineral and other dietary supplements	0.8	1.1	4.2	1.1	-0.0	-0.4	1.2	-0.5	0.6	1.5	2.0	0.1
Breast cancer (self-reported)	0.6	0.7	2.6	-0.3	0.2	-0.9	-1.2	0.4	-0.6	-1.1	-1.6	-0.0
Asthma (self-reported)	0.9	1.8	4.5	1.0	2.1	-1.1	0.5	1.1	1.8	1.5	1.2	1.1
Osteoporosis (self-reported)	0.1	0.2	0.5	0.7	-0.5	-0.0	0.6	-0.7	-0.0	-0.1	0.0	-0.3
Osteoarthritis (self-reported)	0.6	0.8	1.6	-0.3	0.9	0.0	0.6	1.2	1.2	0.8	1.3	1.0
Medication: Aspirin	1.9	2.4	4.9	-0.8	-0.9	1.1	-1.4	-1.4	-2.2	-1.4	-2.0	-2.1
Medication: Gliclazide	1.1	1.2	4.7	0.0	-2.1	0.8	2.2	-0.5	0.5	0.6	-0.5	-0.1
Illnesses of father: None of the above (group 1)	0.7	0.9	3.6	-0.4	-0.6	0.2	1.9	0.0	0.5	-0.6	1.5	1.0
Smoking status: Current	2.1	3.3	8.9	-1.0	-1.6	0.9	-1.7	-1.5	-2.0	-1.2	-3.0	-2.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	5.4	1.0	2.3	0.6	-0.1	0.1	1.1	1.4	0.9	0.4
Whole body water mass	1.2	7.1	13.3	2.5	0.8	-2.3	3.3	1.5	3.6	3.2	2.5	2.9
Leg predicted mass (right)	1.2	6.6	11.8	2.8	0.7	-2.4	2.6	1.4	3.4	3.3	2.5	2.6
Arm fat mass (left)	0.9	3.8	14.7	1.5	-0.0	-3.8	1.9	0.7	2.0	1.9	1.6	1.6
Number of self-reported non-cancer illnesses	0.3	0.5	1.6	-0.3	0.3	-0.3	0.0	0.6	1.0	1.2	1.3	0.4
Average weekly champagne plus white wine intake	1.7	2.3	4.8	1.1	0.4	-0.9	0.5	2.2	1.9	1.9	1.8	1.8
Miserableness	4.0	7.0	15.0	-2.7	-2.2	3.9	-1.6	-2.5	-2.6	-2.3	-2.2	-3.2
Guilty feelings	1.2	1.8	4.0	-2.0	-1.2	1.9	0.0	-1.1	-1.1	-1.3	-1.1	-1.4
Wears glasses or contact lenses	0.2	0.2	0.9	-0.9	0.4	0.2	-0.5	0.0	-0.4	0.3	-0.3	-0.6
Ever taken oral contraceptive pill	0.2	0.3	1.2	-1.1	-0.0	-0.4	-0.1	0.2	-0.2	-0.6	-0.1	0.7
Hearing aid user	0.8	0.9	2.0	-1.2	0.4	1.0	-1.4	-1.2	-0.7	-0.4	-0.0	-1.4
Mother’s age at death	0.5	0.6	2.8	-1.7	-0.9	0.4	0.7	0.6	0.2	0.3	0.8	0.2
Financial situation satisfaction	0.4	0.5	2.4	0.7	1.6	-0.1	0.6	0.7	0.6	0.5	0.3	0.6
Tinnitus: Yes, now most or all of the time	0.5	0.6	3.8	-1.9	-0.0	1.0	0.6	-0.4	-0.1	-0.2	0.2	-0.6
Commuting to job workplace: Public transport	0.5	0.6	3.4	1.8	-0.9	-0.0	0.5	-0.3	0.1	0.8	0.1	-0.1
Eye problems/disorders: Glaucoma	0.3	0.3	0.9	0.5	-0.7	0.4	0.6	0.8	0.5	0.9	-0.1	-0.1
Medication: Blood pressure	0.6	1.1	6.9	0.3	2.6	-0.9	0.2	0.6	0.4	0.2	0.7	0.7
Pain type(s) experienced in last month: Hip pain	0.6	0.8	2.4	-0.4	-0.2	-1.1	1.5	0.2	0.8	0.3	1.1	1.1
Supplements: Fish oil (including cod liver oil)	0.5	0.7	1.7	-0.4	1.0	0.4	-0.6	1.3	0.3	-0.7	-1.3	0.5
High cholesterol (Self-reported)	0.2	0.3	1.5	-0.6	0.3	1.2	0.5	0.6	0.5	0.5	0.4	0.1
Medication: Bendroflumethiazide	0.1	0.2	0.6	0.6	0.6	-0.8	-0.2	-0.4	-0.5	-0.2	-0.2	-0.0
Medication: Paracetamol	0.5	0.8	3.0	-0.9	1.0	0.6	-0.2	-1.0	-1.0	-1.7	-0.3	-0.5
Medication: Lisinopril	0.4	0.5	1.2	0.7	1.0	-0.6	1.1	-0.1	0.6	0.8	-0.1	0.6
Medication: Atorvastatin	2.5	3.1	5.6	2.1	1.4	-1.6	0.6	1.5	1.9	2.3	2.4	1.4
Illnesses of father: High blood pressure	0.3	0.4	1.0	0.7	-0.6	0.2	-1.0	0.7	0.5	0.9	-0.5	-0.2
Alcohol drinker status: Never	1.3	1.6	3.3	-1.1	0.5	1.8	-1.7	-0.6	-1.2	-0.5	-1.6	-1.3
Ever smoked	3.3	5.8	12.0	-3.2	-1.8	1.0	-1.6	-2.0	-2.5	-2.2	-2.7	-3.5
Basal metabolic rate	1.5	8.1	14.6	2.6	0.7	-2.9	3.4	1.6	3.8	3.4	2.8	3.1
Leg fat percentage (left)	0.7	2.4	17.4	0.3	-0.5	-4.2	0.9	-0.2	0.7	0.8	1.1	0.6
Arm fat-free mass (left)	1.0	5.2	9.3	2.0	0.7	-2.6	2.9	1.1	3.0	2.4	2.1	2.6
Number of operations (self-reported)	0.6	0.9	3.4	1.2	1.1	-1.1	-1.9	0.6	0.2	0.3	0.1	0.4
Average weekly beer plus cider intake	0.9	1.4	6.3	0.0	-0.4	0.2	2.5	0.2	1.1	0.1	1.7	1.4
Irritability	3.3	5.5	9.5	-2.2	-2.8	3.1	-1.4	-2.1	-2.7	-2.4	-1.9	-2.3
Risk taking	2.3	3.4	6.9	-1.9	-2.3	-0.3	1.2	-1.8	-1.9	-2.6	-1.9	-1.4
Ever had prostate specific antigen (PSA) test	1.4	1.7	3.1	1.8	-0.3	-1.8	0.9	1.0	1.0	0.8	1.7	1.5
Fractured/broken bones in last 5 years	0.8	1.0	2.4	0.9	-1.2	0.1	1.2	0.7	1.2	1.5	1.0	0.1
Age started oral contraceptive pill	4.8	6.0	7.5	-2.7	-2.7	2.6	-2.4	-2.3	-2.6	-1.9	-2.1	-2.6
Diastolic blood pressure, automated reading	1.2	3.8	8.4	2.5	2.7	-2.9	-0.6	1.1	2.2	2.0	1.2	1.0
Ever depressed for a whole week	0.5	0.6	2.7	0.7	1.3	1.6	0.2	-0.5	0.3	-0.1	0.0	-0.1
Unable to work because of sickness or disability	1.6	2.1	6.1	1.8	2.5	-0.9	0.6	1.3	1.3	0.7	1.2	1.8
Commuting to job workplace: Cycle	0.1	0.2	0.7	-0.3	0.1	-0.2	0.8	0.4	0.2	-0.2	0.5	0.4
Myopia	5.2	7.6	16.6	3.6	-0.1	-1.3	2.5	1.6	3.0	4.1	3.3	2.8
Vascular/heart problems diagnosed by doctor	0.2	0.5	2.1	0.6	-1.4	1.2	-0.6	-0.1	-0.1	-0.5	0.2	-0.1
Cholesterol lowering medication	0.5	0.7	1.6	1.0	-0.4	0.0	1.2	1.3	0.6	0.2	0.3	1.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	3.2	-1.8	0.1	-0.8	1.2	-0.4	-0.3	-0.4	0.5	-0.1
Pain experienced in last month	0.4	0.7	3.9	2.0	-0.9	-0.5	-0.8	0.6	0.2	0.4	0.0	0.7
Supplements: Calcium	0.2	0.3	1.1	-0.3	0.1	1.1	-1.0	-0.3	-0.2	-0.0	-0.2	-0.2
Basal cell carcinoma (self-reported)	0.6	0.7	1.8	-0.9	-0.7	0.4	-0.4	-1.0	-0.9	0.2	-1.0	-1.3
Heart attack/myocardial infarction (self-reported)	0.3	0.3	2.2	0.5	-1.5	0.3	0.1	0.4	0.1	0.6	0.1	0.3
Deep venous thrombosis (DVT) (self-reported)	0.3	0.3	0.9	0.6	-0.9	-0.1	-0.9	-0.2	-0.2	-0.5	-0.6	-0.6
Heart disease (siblings)	0.6	0.7	2.8	-0.3	0.7	-1.7	0.8	-1.1	-0.5	-0.8	-0.5	-0.4
Alcohol drinker status: Previous	0.5	0.6	1.4	0.5	0.6	-0.8	0.6	1.1	0.5	-0.0	1.0	1.2
Pack years of smoking	0.4	0.6	1.6	-0.6	0.7	0.5	0.1	-1.3	-0.9	-1.3	-0.7	-0.4
Impedance of whole body	0.3	1.3	2.3	-1.4	-1.5	1.5	0.1	-0.7	-1.4	-0.8	-0.5	-1.4
Leg fat mass (left)	1.1	4.4	20.3	1.3	-0.1	-4.5	2.0	0.5	2.0	1.9	1.7	1.6
Arm predicted mass (left)	1.1	5.4	10.0	1.9	0.5	-2.8	3.2	1.1	3.0	2.5	2.0	2.6