TWAS hub - RHBDL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1090	0.0330	1.1e-05	0.054	NA	0.078	NA	0.081	3.3e-05	NA	5.7e-07	NA	3.6e-07
2	GTEx	Adipose Visceral Omentum	0.1620	0.0550	2.3e-04	0.132	NA	0.038	NA	0.098	2.4e-07	NA	4.4e-03	NA	8.6e-06
3	GTEx	Artery Aorta	0.1360	0.0460	3.3e-04	0.074	NA	0.109	NA	0.108	7.1e-05	NA	1.4e-06	NA	1.5e-06
4	GTEx	Breast Mammary Tissue	0.1290	0.0520	2.5e-03	0.011	NA	0.070	NA	0.065	8.8e-02	NA	1.8e-04	NA	3.1e-04
5	GTEx	Breast Mammary Tissue (Female)	0.1249	0.0654	3.4e-02	0.013	NA	0.017	NA	0.011	1.3e-01	NA	1.0e-01	NA	1.5e-01
6	GTEx	Cells EBV-transformed lymphocytes	0.4660	0.0820	2.7e-07	0.121	NA	0.160	NA	0.176	9.4e-05	NA	6.6e-06	NA	2.3e-06
7	GTEx	Cells Transformed fibroblasts	0.2240	0.0570	1.3e-05	0.101	NA	0.027	NA	0.075	5.0e-08	NA	3.6e-03	NA	2.9e-06
8	GTEx	Colon Sigmoid	0.3550	0.0990	1.3e-04	0.019	NA	0.055	NA	0.027	6.9e-02	NA	5.2e-03	NA	3.8e-02
9	GTEx	Lung	0.1023	0.0453	2.0e-03	0.053	NA	0.053	NA	0.058	6.4e-05	NA	6.5e-05	NA	3.0e-05
10	GTEx	Muscle Skeletal	0.0853	0.0350	2.4e-03	-0.003	NA	0.000	NA	0.000	8.8e-01	NA	3.3e-01	NA	3.2e-01
11	GTEx	Nerve Tibial	0.1757	0.0442	3.3e-08	0.087	NA	0.128	NA	0.132	1.0e-06	NA	2.6e-09	NA	1.4e-09
12	GTEx	Ovary	0.2660	0.1070	6.4e-03	0.016	NA	0.043	NA	0.035	1.3e-01	NA	3.3e-02	NA	4.7e-02
13	GTEx	Pancreas	0.1600	0.0600	1.6e-03	-0.001	NA	0.002	NA	-0.001	3.5e-01	NA	2.5e-01	NA	3.7e-01
14	GTEx	Skin Sun Exposed Lower leg	0.1150	0.0380	5.1e-05	0.048	NA	0.028	NA	0.041	7.0e-05	NA	2.0e-03	NA	2.5e-04
15	GTEx	Stomach	0.2360	0.0820	8.1e-04	0.006	NA	0.005	NA	0.006	1.6e-01	NA	1.8e-01	NA	1.5e-01
16	GTEx	Testis	0.2460	0.0630	5.7e-06	0.193	NA	0.136	NA	0.174	5.6e-09	NA	1.3e-06	NA	3.5e-08
17	GTEx	Thyroid	0.1200	0.0340	1.9e-06	0.095	NA	0.104	NA	0.117	9.8e-08	NA	2.5e-08	NA	2.9e-09
18	GTEx	Whole Blood	0.1000	0.0370	5.9e-04	0.064	NA	0.014	NA	0.047	1.6e-06	NA	1.6e-02	NA	3.6e-05
19	METSIM	Adipose	0.0596	0.0201	6.8e-06	0.044	0.036	0.038	0.034	0.050	3.0e-07	3.9e-06	1.7e-06	6.7e-06	4.6e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	14	15	16	17	18	19
Smoking Status	9.6	22.9	43.1	-5.3	-3.6	-6.0	-3.5	-0.3	-5.6	-4.6	-3.5	-4.9	-5.7	-5.4	-5.7	-6.2	0.1	-6.3	-6.6	-5.7	-3.1
Loud music exposure frequency	9.6	10.5	15.1	-3.6	-3.8	-3.7	-3.1	-2.3	-3.2	-3.2	-2.8	-3.5	-3.3	-3.6	-3.5	-3.9	-1.9	-3.4	-3.4	-3.4	-3.8
Average weekly champagne plus white wine intake	8.0	11.0	19.0	3.7	3.3	4.0	2.8	1.5	3.6	3.4	2.0	3.6	3.7	3.6	3.7	4.4	2.3	3.7	4.2	3.5	3.1
Standing height	7.8	77.2	127.7	10.3	8.5	10.7	7.5	2.5	9.3	8.7	8.3	7.3	9.8	10.4	9.9	11.3	2.8	10.2	10.5	9.9	8.7
Height	7.6	146.3	240.2	14.6	13.1	14.8	12.1	3.5	12.6	11.0	11.0	9.2	12.9	14.1	13.1	15.5	3.6	13.8	14.2	13.0	13.4
Comparative height size at age 10	7.6	41.8	66.1	7.9	7.3	7.9	6.2	2.5	6.5	6.7	5.4	4.4	7.1	7.5	6.5	8.1	3.5	7.1	7.2	7.2	7.3
Ever smoked	7.6	13.3	23.4	-4.2	-3.3	-4.6	-2.9	-0.5	-4.1	-3.2	-2.2	-4.1	-3.9	-4.2	-4.3	-4.7	-0.2	-4.8	-4.8	-4.1	-3.1
Sitting height	6.1	43.4	77.8	8.0	6.6	8.0	6.3	0.9	7.4	5.9	5.3	5.0	7.2	7.7	7.6	8.8	1.3	7.6	8.0	7.1	6.9
Age at first live birth	5.7	10.1	17.1	3.4	2.5	3.7	3.9	0.8	3.2	3.2	2.2	3.2	3.5	3.8	3.8	3.9	0.7	3.8	4.1	3.7	2.5
Past tobacco smoking	5.6	10.3	19.1	4.0	3.4	3.8	2.9	0.7	3.8	2.2	1.6	3.6	3.1	3.4	3.9	4.4	0.6	4.0	4.2	3.0	3.3
Number of incorrect matches in round	5.4	9.0	21.7	3.3	2.6	3.0	2.5	4.7	4.1	2.3	3.1	2.5	3.0	3.4	3.5	3.2	0.9	3.0	3.1	2.7	3.1
Alcohol intake frequency.	5.2	12.0	19.9	-4.5	-4.1	-4.0	-3.7	-1.4	-3.9	-3.0	-3.6	-2.3	-3.8	-3.8	-3.9	-4.3	-2.1	-3.3	-4.0	-3.2	-3.9
Qualifications: None of the above	5.0	10.8	21.1	-3.6	-2.1	-4.0	-1.3	0.3	-3.8	-3.0	-3.0	-3.3	-4.0	-4.0	-4.2	-4.4	-0.0	-4.2	-4.6	-3.7	-2.1
Current tobacco smoking	4.7	7.6	14.9	-2.8	-1.4	-3.4	-1.9	0.5	-3.5	-2.8	-2.8	-2.0	-3.3	-3.3	-3.3	-3.3	0.6	-3.8	-3.9	-3.5	-1.3
Townsend deprivation index at recruitment	4.6	6.5	11.1	-2.7	-2.1	-2.8	-2.9	-1.8	-2.7	-2.4	-1.5	-3.0	-2.9	-3.0	-3.3	-2.9	-1.8	-2.6	-3.0	-2.4	-2.6
Trunk predicted mass	4.5	25.5	41.6	5.4	4.9	6.5	5.4	4.5	4.7	5.8	4.4	2.8	5.7	5.7	4.9	6.4	2.0	5.7	5.7	6.2	4.5
Osteoarthritis (self-reported)	4.5	5.8	9.2	-2.8	-1.9	-2.7	-1.5	0.8	-2.8	-2.4	-1.8	-2.9	-2.7	-3.0	-3.0	-2.8	-1.0	-2.7	-3.0	-2.7	-2.5
Knee pain experienced in last month	4.4	6.9	13.7	-2.3	-1.5	-3.2	-2.1	-0.5	-2.9	-2.4	-2.8	-2.8	-2.5	-3.3	-3.7	-3.3	-0.1	-3.6	-3.6	-3.0	-1.4
Trunk fat-free mass	4.3	24.8	40.3	5.3	4.8	6.3	5.4	4.4	4.7	5.8	4.3	2.8	5.7	5.6	4.8	6.3	2.0	5.5	5.6	6.1	4.5
Alcohol intake versus 10 years previously	4.3	6.4	11.6	-3.4	-2.6	-2.8	-1.6	-1.2	-3.0	-1.9	-2.5	-2.8	-3.0	-2.5	-2.9	-3.2	-0.4	-2.7	-3.1	-2.5	-2.7
Qualifications: College or University degree	4.3	13.5	25.5	4.3	2.3	4.3	2.0	0.4	5.0	3.1	3.8	3.7	4.3	4.1	4.7	4.8	-0.4	4.9	5.1	4.0	1.6
Smoking status: Previous	4.2	6.3	11.9	-3.3	-2.9	-2.9	-2.3	-0.9	-3.1	-1.5	-0.9	-2.8	-2.5	-2.5	-2.9	-3.5	-0.1	-3.0	-3.1	-2.2	-2.8
Whole body fat-free mass	4.2	23.9	37.8	5.1	4.7	6.2	5.5	4.4	4.5	5.8	4.2	2.8	5.5	5.5	4.7	6.0	2.4	5.4	5.4	6.0	4.5
Pain type(s) experienced in last month: Hip pain	4.2	5.2	9.3	-2.2	-1.4	-2.7	-0.5	0.9	-2.2	-2.8	-3.1	-2.4	-2.7	-2.8	-2.7	-2.5	-1.0	-2.8	-2.9	-2.9	-1.6
Long-standing illness, disability or infirmity	4.0	6.2	11.2	-2.5	-3.2	-3.3	-1.8	0.8	-1.7	-3.3	-2.0	-2.0	-2.9	-2.9	-2.0	-3.1	-1.5	-2.5	-2.5	-3.3	-2.9
Back pain experienced in last month	4.0	5.8	11.8	-2.6	-2.1	-3.1	-2.7	-0.0	-2.6	-2.2	-1.6	-1.7	-2.5	-2.5	-3.2	-3.2	0.4	-3.2	-3.4	-2.9	-1.6
Smoking status: Current	4.0	6.4	12.8	-2.7	-1.4	-3.1	-1.9	0.1	-3.2	-2.5	-2.5	-1.7	-3.1	-2.9	-3.0	-3.1	0.5	-3.5	-3.6	-3.1	-1.1
Tense / ‘highly strung’	3.9	6.4	12.6	3.1	3.2	2.9	3.2	1.0	2.6	2.4	1.1	2.4	2.6	3.0	2.4	2.7	1.4	2.5	2.6	2.6	3.5
Leg fat-free mass (right)	3.9	20.9	32.3	4.7	4.2	5.6	5.3	4.2	4.3	5.6	3.8	2.9	5.3	5.1	4.4	5.4	2.5	5.0	5.0	5.7	4.0
Whole body water mass	3.9	22.0	34.9	4.9	4.5	5.9	5.2	4.4	4.3	5.6	4.1	2.6	5.4	5.2	4.5	5.8	2.3	5.2	5.2	5.8	4.2
Arm predicted mass (right)	3.8	19.5	30.5	4.7	4.7	5.5	5.0	4.3	3.8	5.3	3.5	2.4	5.0	5.0	4.1	5.3	2.4	4.7	4.6	5.4	4.6
Leg predicted mass (right)	3.8	20.4	31.8	4.6	4.1	5.6	5.3	4.1	4.2	5.5	3.8	2.9	5.3	5.0	4.4	5.3	2.5	5.0	4.9	5.6	3.9
Age at First Birth	3.6	5.3	10.0	2.3	2.1	3.0	2.5	-0.3	2.6	2.3	1.9	0.0	2.3	2.7	2.9	2.9	0.6	3.1	3.2	2.8	1.6
Leg fat-free mass (left)	3.6	19.2	29.4	4.5	4.1	5.4	5.2	4.3	4.0	5.3	3.6	2.6	5.0	4.8	4.1	5.1	2.5	4.8	4.7	5.4	3.9
Leg predicted mass (left)	3.6	18.9	28.9	4.4	4.1	5.4	5.2	4.3	4.0	5.3	3.6	2.6	5.0	4.8	4.1	5.1	2.5	4.7	4.7	5.4	3.9
Forced expiratory volume in 1-second (FEV1), predicted	3.6	7.4	14.4	3.8	2.7	3.1	2.8	0.4	3.3	2.5	2.1	1.6	3.4	3.3	3.0	3.3	1.9	3.1	2.9	2.6	2.6
Hearing aid user	3.6	4.1	7.0	-2.3	-2.2	-2.5	-0.9	0.8	-1.6	-1.8	-2.3	-2.1	-2.4	-2.6	-1.9	-2.6	-0.8	-2.3	-2.3	-2.0	-2.5
Blood Platelet Count	3.5	40.4	80.3	-7.2	-6.5	-7.6	-9.0	-1.9	-6.8	-6.8	-1.8	-5.2	-6.9	-7.3	-6.1	-7.6	-4.4	-7.1	-7.2	-7.1	-6.2
Respiratory disease	3.5	7.7	18.4	-2.9	-4.0	-3.3	-1.4	0.6	-1.3	-3.8	-2.7	-1.6	-3.0	-3.3	-2.0	-2.9	-2.7	-2.5	-2.3	-3.6	-4.3
Severe depression (siblings)	3.5	4.0	10.8	-2.2	-3.3	-2.1	-2.4	1.9	-1.5	-1.8	-0.3	-1.6	-1.2	-2.0	-1.8	-2.0	-1.9	-2.0	-1.7	-2.0	-3.2
Medication: Blood pressure	3.5	6.7	12.1	3.0	1.8	3.2	1.6	1.6	2.8	2.3	1.4	2.8	3.1	3.2	3.1	3.1	0.1	3.3	3.5	2.9	2.4
Alzheimer’s Disease (including proxy)	3.4	4.9	10.9	-2.2	-1.3	-2.3	-2.7	-2.3	-3.3	-1.9	-1.0	-2.4	-2.5	-2.5	-2.8	-2.4	0.4	-2.5	-2.5	-2.4	-1.8
Arm fat-free mass (right)	3.4	17.4	27.6	4.5	4.3	5.2	4.7	4.0	3.6	5.0	3.2	2.0	4.7	4.7	3.9	5.0	2.3	4.5	4.3	5.2	4.3
Basal metabolic rate	3.4	18.6	28.8	4.5	4.3	5.4	5.1	4.6	3.8	5.1	3.4	2.2	4.9	4.7	4.0	5.2	2.2	4.6	4.6	5.2	4.1
Frequency of tiredness / lethargy in last 2 weeks	3.3	5.4	9.1	-2.6	-2.5	-2.8	-1.7	1.1	-2.5	-2.8	-2.2	-1.6	-2.6	-2.5	-2.2	-2.8	-1.3	-2.9	-2.4	-3.0	-2.0
Unable to work because of sickness or disability	3.3	4.3	8.4	-2.5	-2.2	-2.7	-1.4	0.9	-2.1	-2.1	-2.2	-1.1	-2.4	-2.4	-1.8	-2.9	-0.2	-2.5	-2.4	-2.5	-2.1
Pulse rate	3.2	5.4	11.4	-2.7	-2.5	-2.6	-1.5	0.4	-2.1	-3.4	-3.1	-1.4	-3.1	-2.4	-1.5	-2.6	-2.5	-1.9	-2.2	-2.9	-2.1
Pain experienced in last month	3.2	5.4	10.2	2.1	1.2	2.9	1.7	-1.4	2.7	2.2	3.2	1.6	2.5	2.4	2.7	2.9	-1.0	3.2	3.2	2.9	0.6
Happiness	3.1	3.8	7.9	2.3	1.4	2.3	1.5	0.1	2.8	1.2	1.8	1.9	1.7	2.0	2.2	2.7	-1.1	2.7	2.7	2.0	1.4
Reaction Time	3.0	5.8	12.6	3.0	1.1	2.3	1.8	3.2	3.6	2.3	0.8	3.1	3.3	2.4	2.6	2.3	0.3	2.7	2.6	2.7	1.4
Wheeze or whistling in the chest in last year	3.0	5.3	10.0	-2.0	-1.3	-2.8	-1.4	0.7	-2.3	-2.9	-2.5	-2.4	-2.7	-2.9	-2.7	-2.5	-0.6	-3.1	-2.8	-3.2	-1.3
Pulse rate, automated reading	3.0	9.6	17.6	-3.9	-3.1	-3.8	-2.4	0.8	-3.3	-3.8	-2.8	-1.9	-4.2	-3.6	-2.7	-3.6	-1.8	-3.5	-3.3	-3.9	-2.9
Had major operations	2.9	3.4	7.1	-1.9	-1.4	-2.5	-0.6	0.1	-2.0	-1.8	-1.4	-1.2	-2.3	-2.4	-2.3	-2.2	-0.2	-2.7	-2.5	-2.2	-1.2
Average weekly spirits intake	2.8	3.4	8.5	1.8	1.0	1.9	1.6	1.3	2.0	1.2	1.5	2.9	1.6	2.1	2.8	2.1	-0.1	2.2	2.6	1.6	1.7
Comparative body size at age 10	2.7	7.5	13.9	-2.7	-1.4	-3.0	-1.8	0.9	-3.7	-2.7	-2.2	-3.4	-3.1	-3.4	-3.5	-3.2	0.2	-3.4	-3.4	-3.3	-2.1
Neck or shoulder pain in last month	2.7	3.9	6.7	-2.6	-2.0	-2.2	-1.8	-0.4	-2.5	-2.0	-2.1	-1.9	-2.5	-2.1	-1.8	-2.3	-0.6	-2.0	-2.2	-2.2	-1.9
Qualifications: NVQ or HND or HNC or equivalent	2.7	3.3	9.6	-1.6	-0.8	-1.9	-1.6	-1.0	-2.2	-2.1	-3.1	-1.9	-2.1	-2.0	-1.9	-1.8	-0.6	-2.1	-1.9	-2.1	-0.8
Arm fat-free mass (left)	2.7	13.5	21.7	3.8	3.9	4.7	4.3	3.9	3.0	4.6	2.9	1.4	4.2	4.0	3.1	4.5	2.1	3.8	3.8	4.6	3.6
Arm predicted mass (left)	2.7	14.0	22.7	3.9	4.0	4.8	4.3	4.0	3.1	4.6	3.0	1.5	4.3	4.1	3.1	4.5	1.9	3.9	3.8	4.7	3.7
Diabetes (father)	2.6	3.3	5.9	-1.8	-2.3	-2.3	-2.4	-0.5	-1.4	-1.9	-1.7	-1.1	-1.9	-2.0	-1.6	-2.1	-0.9	-2.0	-1.9	-2.1	-2.1
High blood pressure	2.6	7.3	13.1	2.8	1.5	3.1	1.6	2.2	2.3	2.7	1.9	3.6	3.1	3.4	3.6	3.1	0.8	3.2	3.5	3.0	2.6
Breastfed as a baby	2.6	3.2	7.3	1.9	0.3	2.1	-0.0	-0.1	2.3	1.2	2.1	1.4	2.5	1.8	2.1	2.5	-1.8	2.4	2.7	1.9	0.3
Age at last live birth	2.6	3.8	7.0	2.0	1.5	2.2	2.7	2.0	1.7	1.9	0.5	2.2	1.8	2.1	2.4	2.1	1.3	2.3	2.5	2.1	1.7
Asthma (self-reported)	2.6	5.1	11.6	-2.1	-3.3	-2.7	-1.8	0.3	-1.0	-2.7	-3.1	-1.8	-2.1	-2.6	-1.9	-2.3	-1.9	-2.1	-2.0	-2.6	-3.4
Tinnitus: Yes, now most or all of the time	2.6	3.1	7.5	-2.2	-2.2	-1.8	-2.7	1.1	-2.1	-0.6	-0.7	-1.4	-1.1	-1.9	-2.2	-2.2	-0.7	-1.8	-2.1	-1.1	-2.3
Medication: Bendroflumethiazide	2.6	3.9	6.6	2.0	1.6	2.4	1.3	0.6	1.5	2.3	2.1	2.4	2.3	2.4	2.3	2.3	-0.0	2.1	2.4	2.6	2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.5	3.0	4.5	1.9	2.0	2.0	1.4	1.7	1.2	1.8	1.4	1.9	1.5	1.7	1.5	2.1	2.0	1.9	2.0	1.8	1.9
Wears glasses or contact lenses	2.5	2.9	7.6	2.0	0.6	1.8	0.6	0.3	2.8	1.2	1.3	1.9	2.0	2.0	2.5	1.8	0.4	2.2	2.2	1.6	1.1
Alcohol usually taken with meals	2.4	3.9	7.5	2.3	2.0	2.5	0.1	0.5	1.9	2.2	1.4	2.7	2.6	2.2	2.2	2.5	0.6	2.2	2.1	2.4	1.8
Hypertension (Self-reported)	2.4	6.6	13.9	2.6	1.3	2.9	1.2	2.0	2.2	2.5	1.9	3.7	2.9	3.3	3.5	2.8	0.6	3.1	3.3	2.9	2.5
Mouth/teeth dental problems: Mouth ulcers	2.4	3.7	7.9	-2.2	-2.5	-2.2	-2.2	-0.4	-1.5	-1.4	-1.9	-1.6	-1.4	-2.3	-2.4	-2.3	-1.6	-2.1	-2.0	-1.6	-2.8
Deep venous thrombosis (DVT) (self-reported)	2.4	3.1	7.9	-1.7	-2.0	-1.9	-2.8	-0.9	-1.7	-1.6	-1.6	-1.3	-1.6	-2.2	-2.0	-1.9	-0.7	-1.8	-1.7	-1.8	-2.4
Alzheimer’s Disease (in father)	2.3	2.5	5.7	-1.4	-1.5	-1.9	-1.6	-0.0	-1.6	-2.0	-2.4	-0.6	-1.9	-2.1	-1.6	-1.5	-0.7	-1.6	-1.5	-2.0	-1.8
Prostate Cancer	2.3	3.2	6.8	2.2	1.6	1.8	1.9	1.5	2.6	1.0	0.9	2.6	1.8	2.0	2.3	1.5	1.2	1.7	1.8	1.2	2.1
Lung FVC	2.3	11.8	18.1	-4.1	-2.9	-3.9	-3.0	-3.1	-4.0	-3.6	-1.7	-4.2	-4.3	-3.8	-3.6	-3.7	-0.7	-3.9	-3.8	-4.1	-3.2
Sensitivity / hurt feelings	2.3	4.0	7.8	2.0	1.9	2.1	2.1	0.6	1.7	2.0	1.2	2.5	1.7	2.5	2.5	2.3	1.9	1.9	2.3	1.9	2.8
Pulse wave Arterial Stiffness index	2.3	2.7	11.6	1.4	0.8	1.6	1.5	0.8	1.6	1.1	-0.1	3.4	1.2	2.0	2.6	1.5	1.1	1.9	2.0	1.3	1.6
Medication: Amlodipine	2.3	3.3	8.0	1.5	1.0	2.1	1.3	1.1	1.3	2.2	1.3	2.8	1.7	2.1	2.4	2.3	0.9	2.0	2.4	2.2	1.4
Medication: Allopurinol	2.3	3.1	6.6	2.6	2.1	2.2	1.1	-0.7	2.1	1.4	0.8	1.1	1.8	1.9	1.8	2.4	1.1	2.2	2.3	1.6	1.9
Heart disease (mother)	2.3	2.9	7.6	2.5	1.4	2.1	1.0	0.8	2.7	1.4	1.3	1.0	2.4	1.9	1.6	1.6	-0.2	2.1	1.7	1.8	1.5
HbA1C	2.2	2.4	4.3	-2.1	-1.6	-1.7	-0.0	0.7	-1.9	-1.4	-1.5	0.0	-1.8	-2.0	-1.9	-1.8	-0.8	-1.9	-1.8	-1.7	-1.8
Illnesses of siblings	2.2	3.1	6.0	-1.8	-2.0	-2.0	-2.3	-2.0	-1.2	-1.4	-1.8	-1.0	-1.3	-2.0	-1.9	-2.1	-1.3	-1.7	-1.9	-1.5	-2.4
Qualifications: A levels/AS levels or equivalent	2.2	4.9	13.4	1.9	0.2	2.5	0.7	-1.4	2.7	1.6	1.9	2.4	2.3	2.3	3.2	3.2	-1.2	3.2	3.7	2.3	0.2
Asthma	2.2	4.3	10.2	-1.9	-3.1	-2.5	-1.6	0.1	-0.8	-2.4	-3.0	-1.5	-1.9	-2.3	-1.6	-2.2	-1.7	-1.9	-1.9	-2.3	-3.2
Ever highly irritable/argumentative for 2 days	2.2	2.6	5.2	-1.7	-1.0	-2.1	-1.8	-0.1	-1.5	-2.0	-1.5	-1.1	-2.3	-1.9	-1.6	-1.9	0.1	-2.0	-2.0	-2.3	-0.6
High blood pressure (siblings)	2.2	3.2	5.8	1.9	2.1	2.2	1.8	1.4	1.1	1.9	1.8	0.9	1.7	2.1	1.7	2.2	1.5	1.8	2.0	1.8	2.4
Chest pain or discomfort	2.2	3.1	5.5	-2.3	-1.5	-1.9	-0.8	2.1	-1.9	-1.2	-1.6	-2.1	-2.2	-2.1	-2.0	-1.9	0.4	-2.0	-2.0	-1.7	-1.9
Miserableness	2.2	3.9	7.0	-1.9	-1.1	-2.4	-1.2	-1.0	-2.3	-2.1	-2.2	-2.0	-2.4	-2.1	-2.5	-2.1	0.4	-2.7	-2.5	-2.6	-0.9
Medication: Lisinopril	2.2	2.8	6.2	1.9	0.7	1.7	1.5	0.6	2.5	1.4	-0.1	2.3	1.8	1.9	2.5	1.9	1.1	1.9	2.2	1.5	1.4
Shortness of breath walking on level ground	2.1	2.5	4.8	-1.4	-0.8	-1.9	-2.2	0.2	-1.3	-1.5	-1.6	-1.8	-1.9	-1.7	-1.4	-1.8	1.6	-2.1	-1.9	-2.2	-0.6
Medication: Blood pressure	2.1	3.6	7.3	1.5	1.2	2.1	0.5	0.0	1.4	2.5	1.6	2.7	1.8	2.5	2.6	2.0	0.7	2.2	2.2	2.7	2.0
Mean time to correctly identify matches	2.1	4.0	12.3	2.6	0.5	1.6	1.2	2.7	3.5	1.2	0.9	2.9	2.6	1.9	2.4	1.8	-0.9	2.3	2.2	1.8	0.9
Financial situation satisfaction	2.1	2.7	4.2	-1.8	-1.2	-1.7	-1.5	-0.6	-1.9	-1.6	-2.0	-1.8	-2.0	-2.0	-2.0	-1.5	-0.7	-1.8	-1.7	-1.7	-1.7
Number of operations (self-reported)	2.1	3.1	5.4	-1.8	-2.0	-2.3	-1.9	-0.2	-1.7	-2.2	-0.8	-1.4	-2.1	-2.0	-1.7	-2.0	-0.7	-2.1	-2.0	-2.3	-1.5
Exposure to tobacco smoke at home	2.0	2.3	5.0	-1.7	-1.1	-1.9	-0.2	0.3	-1.8	-1.5	-0.8	-2.0	-1.7	-1.6	-1.6	-2.2	0.3	-1.9	-2.0	-1.9	-1.1
Gout (self-reported)	2.0	2.7	6.1	2.1	1.5	2.1	0.8	-1.1	2.0	1.2	-0.1	1.0	1.6	2.0	2.0	2.1	0.4	2.5	2.4	1.7	1.3
Medication: Ventolin 100micrograms inhaler	2.0	2.5	6.2	-1.8	-2.1	-1.7	-1.7	0.3	-1.0	-1.8	-2.1	-1.3	-1.5	-1.7	-1.4	-1.4	-1.3	-1.4	-1.2	-1.8	-2.5
Mean Putamen Volume	1.9	2.2	4.8	-2.2	-1.7	-1.8	-1.5	0.6	-1.6	-1.1	-1.2	-0.8	-1.9	-1.7	-1.4	-1.6	-0.0	-1.8	-1.6	-1.5	-1.6
Leg fat percentage (right)	1.9	6.9	13.5	-2.1	-0.6	-2.9	-1.0	2.5	-3.0	-2.6	-3.1	-3.2	-3.0	-3.1	-3.5	-3.2	0.3	-3.5	-3.7	-3.1	-0.5
Vascular/heart problems diagnosed by doctor	1.9	5.1	10.6	-2.2	-1.2	-2.5	-1.3	-2.3	-1.6	-2.5	-1.7	-3.2	-2.5	-2.8	-2.9	-2.4	-1.1	-2.6	-2.7	-2.6	-2.2
Maternal smoking around birth	1.8	2.7	6.4	-2.1	-1.8	-1.5	-1.3	0.3	-1.8	-1.0	-1.9	-2.2	-1.5	-2.0	-1.9	-1.8	-0.4	-1.5	-1.7	-1.3	-2.5
Stomach or abdominal pain in last month	1.8	2.2	7.0	-1.8	-1.2	-1.6	0.2	1.6	-1.1	-1.3	-2.6	-1.0	-1.7	-1.9	-1.6	-1.3	-0.7	-1.8	-1.6	-1.5	-1.4
Schizophrenia (2018)	1.7	3.4	10.3	1.8	3.2	2.3	1.1	1.3	0.6	2.4	1.5	0.0	1.8	1.7	1.0	2.4	1.8	1.2	1.6	2.1	3.2
Fed-up feelings	1.7	3.0	6.6	-2.2	-1.6	-2.2	-0.4	-0.6	-1.9	-0.9	-2.2	-1.3	-1.7	-1.9	-2.1	-2.6	0.4	-2.4	-2.5	-1.5	-1.6
Supplements: Glucosamine	1.7	2.2	3.8	-1.9	-1.9	-1.9	-1.3	0.7	-1.5	-1.6	-0.9	-0.6	-1.9	-1.7	-1.0	-1.7	-0.7	-1.8	-1.3	-1.8	-1.9
Allergy	1.7	4.0	9.5	2.3	2.8	2.3	1.5	-1.5	1.5	1.8	2.3	1.7	1.9	2.4	2.1	2.1	1.0	1.9	1.8	2.0	3.1
Leg fat percentage (left)	1.7	6.1	11.9	-2.0	-0.4	-2.7	-0.9	2.4	-2.9	-2.3	-3.0	-2.8	-2.8	-2.9	-3.2	-3.0	0.6	-3.3	-3.5	-2.8	-0.3
Alcohol drinker status: Previous	1.7	1.9	3.3	-1.7	-1.8	-1.7	-0.7	-0.3	-0.9	-1.7	-1.7	-0.7	-1.8	-1.5	-1.0	-1.4	-1.4	-1.2	-1.3	-1.6	-1.8
Weight	1.6	7.8	23.9	3.0	3.1	3.2	3.9	4.9	2.3	2.9	1.2	1.0	2.7	2.8	2.3	3.0	1.9	2.6	2.6	3.0	3.1
Blood clot in the leg (DVT)	1.6	2.0	6.3	-1.4	-1.5	-1.4	-2.5	-0.8	-1.5	-1.2	-1.2	-0.9	-1.2	-1.8	-1.6	-1.5	-0.3	-1.5	-1.3	-1.4	-1.9
LDL Cholesterol	1.5	2.5	4.7	-2.1	-1.4	-1.8	-1.2	0.4	-2.2	-1.9	-0.5	0.0	-2.2	-1.7	-1.8	-1.5	-1.4	-1.8	-1.8	-1.8	-1.4
Multivitamins +/- minerals	1.5	2.0	6.0	1.4	0.7	1.5	0.2	0.9	1.8	1.1	2.4	1.7	1.4	1.3	1.7	1.7	0.2	1.7	1.9	1.4	0.6
Fluid intelligence score	1.5	3.1	7.4	1.6	0.1	2.2	0.6	0.3	2.4	1.1	2.2	1.2	1.9	2.3	2.5	2.0	-1.3	2.7	2.7	1.8	0.1
Illnesses of father: Heart disease	1.5	2.0	5.6	1.3	1.4	1.3	1.2	0.9	0.8	0.9	2.4	1.8	0.6	1.8	1.8	1.7	1.6	1.3	1.6	0.9	2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.8	7.6	-1.6	-0.8	-1.4	-1.4	0.3	-1.7	-0.5	-2.8	-0.6	-1.1	-1.2	-1.6	-1.4	0.6	-1.8	-1.6	-1.2	-0.8
Bipolar Disorder or Schizophrenia	1.4	3.4	10.3	1.5	3.0	2.1	1.6	1.8	0.6	2.4	1.1	0.0	1.4	1.8	1.2	2.2	2.5	1.1	1.5	2.0	3.2
Medication: Co-codamol	1.4	1.6	3.5	-1.4	-0.5	-1.5	-0.8	1.1	-1.6	-1.2	-0.4	-0.7	-1.4	-1.4	-1.7	-1.4	0.8	-1.9	-1.8	-1.6	-0.1
Hair/balding pattern: Pattern 2	1.4	1.8	3.7	1.4	1.8	1.6	1.9	0.3	1.2	0.8	1.6	1.3	1.1	1.4	1.4	1.6	-0.3	1.5	1.6	1.3	1.5
Forced vital capacity (FVC)	1.4	5.2	8.9	2.3	2.4	2.7	1.9	-2.0	1.9	2.6	2.6	1.0	2.2	2.6	2.5	3.0	2.4	2.3	2.6	2.4	2.2
Commuting to job workplace: Walk	1.4	1.5	4.9	-0.9	-1.8	-1.3	-2.2	-1.4	-0.1	-1.1	-0.7	-1.1	-0.4	-0.9	-1.1	-1.4	-1.6	-0.9	-1.3	-1.0	-1.3
Worry (Nagel 2018)	1.3	2.8	8.9	1.8	1.3	1.7	1.0	-0.2	1.6	1.5	0.6	3.0	1.4	2.4	2.1	1.7	0.9	1.7	1.9	1.6	2.6
Vitamin and mineral supplements	1.3	1.7	6.1	-1.3	-0.4	-1.4	-0.5	-0.7	-1.7	-0.9	-2.5	-1.0	-1.2	-1.2	-1.6	-1.6	0.3	-1.9	-2.0	-1.4	-0.1
Peak expiratory flow (PEF)	1.3	3.1	6.0	1.7	1.9	2.2	1.6	-1.5	1.4	2.1	0.9	0.8	1.9	2.1	1.7	2.4	1.9	1.9	2.0	1.9	1.8
Exposure to tobacco smoke outside home	1.3	1.7	3.6	-1.9	-1.1	-1.5	-1.3	-0.5	-1.6	-0.8	-1.3	-0.5	-1.9	-1.5	-1.3	-1.1	1.7	-1.7	-1.3	-1.5	-0.6
Mouth/teeth dental problems: Loose teeth	1.3	1.5	6.5	-0.7	-2.0	-1.2	-0.9	-1.2	0.3	-1.4	-1.3	-0.6	-0.6	-1.0	-0.3	-1.3	-2.5	-0.4	-0.5	-0.9	-2.4
Ever had hysterectomy (womb removed)	1.2	1.4	5.7	0.7	0.9	1.1	-0.5	0.1	0.3	1.8	2.4	1.4	0.9	1.2	1.0	1.0	1.7	1.1	1.0	1.5	1.2
Arm fat percentage (right)	1.2	4.7	9.1	-2.1	-1.1	-2.4	-0.3	3.0	-2.2	-2.1	-2.7	-2.3	-2.5	-2.5	-2.6	-2.6	0.2	-2.6	-2.6	-2.5	-1.1
Hip circumference	1.2	5.3	27.7	2.4	2.6	2.4	3.6	5.3	1.9	1.7	0.6	0.4	1.8	1.9	1.6	2.4	1.0	1.9	2.0	1.9	2.6
Time employed in main current job	1.2	1.4	4.6	1.1	1.3	1.3	1.3	2.2	1.1	1.3	-0.0	0.9	1.3	1.0	0.9	1.3	0.6	1.2	1.1	1.4	1.1
Forced expiratory volume in 1-second (FEV1)	1.2	4.2	7.8	1.9	2.4	2.5	1.6	-1.9	1.4	2.4	1.7	0.8	1.9	2.4	2.1	2.8	2.6	2.1	2.3	2.2	2.0
Length of working week for main job	1.2	1.3	8.7	-0.9	-0.8	-1.1	-0.6	3.0	-0.7	-1.4	-0.8	-0.4	-1.0	-1.2	-0.9	-0.7	-0.5	-1.2	-0.9	-1.4	-0.9
Illness, injury, bereavement, stress in last 2 years	1.2	1.4	2.5	1.3	0.5	1.3	0.5	-0.7	1.5	1.5	1.5	0.7	1.2	1.3	1.4	1.5	1.2	1.6	1.5	1.4	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	11.4	-1.0	0.1	-0.9	-0.6	3.4	-1.1	-0.9	-1.9	-0.5	-1.3	-1.1	-1.1	-0.7	-0.1	-1.1	-1.1	-1.0	0.1
Friendships satisfaction	1.2	1.5	4.2	1.4	1.2	1.6	1.6	0.7	1.6	0.6	0.6	0.2	0.7	1.1	1.3	2.1	-0.2	1.7	1.8	1.1	0.6
Breast cancer (self-reported)	1.2	1.5	3.3	1.7	0.8	1.2	1.4	1.2	1.8	0.5	0.8	1.0	1.5	1.3	1.8	1.4	-0.3	1.4	1.5	0.9	0.6
Commuting to job workplace: Cycle	1.2	1.4	4.2	1.9	0.7	1.2	-0.0	-0.7	2.1	0.4	0.6	0.7	1.4	1.3	1.6	1.4	-1.0	1.6	1.7	1.0	0.7
Schizophrenia (2014)	1.1	2.5	10.4	1.3	3.2	1.9	1.0	1.1	0.1	2.0	1.6	0.0	1.1	1.2	0.4	1.8	2.1	0.7	1.0	1.6	2.9
Allergy or Eczema	1.1	2.8	7.6	-2.2	-2.3	-1.7	-1.1	1.0	-1.3	-1.0	-1.4	-2.0	-1.3	-2.0	-2.0	-2.0	-1.3	-1.5	-1.8	-1.2	-2.8
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	3.3	-1.6	-1.7	-1.4	-0.8	-0.0	-1.0	-1.2	-0.5	-1.5	-1.3	-1.4	-1.3	-1.4	-0.7	-1.3	-1.0	-1.3	-1.8
Age when periods started (menarche)	1.1	2.6	8.0	-2.1	-2.8	-1.8	-2.0	-1.2	-2.0	-0.9	-0.8	-0.6	-1.0	-1.3	-1.2	-2.0	-1.5	-1.4	-1.5	-1.1	-2.5
Serious illness, injury or assault to yourself	1.1	1.3	3.1	-1.4	-0.5	-1.2	1.5	1.6	-1.2	-1.3	-1.8	-0.6	-1.8	-1.2	-0.7	-0.7	0.2	-1.1	-0.9	-1.4	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.6	6.6	-1.3	-0.2	-1.6	0.8	-0.0	-2.1	-1.1	-2.3	-2.5	-1.6	-2.0	-2.6	-1.4	0.7	-2.0	-2.1	-1.6	-1.0
Father’s age at death	1.1	1.4	3.5	1.3	0.3	1.3	0.7	0.9	1.7	0.7	-0.9	1.7	1.0	1.1	1.7	1.5	0.6	1.7	1.9	0.9	0.5
Forced vital capacity (FVC), Best measure	1.1	4.2	8.2	1.9	1.7	2.4	1.7	-1.3	2.0	2.3	2.9	0.8	2.1	2.4	2.5	2.6	1.8	2.3	2.4	2.3	1.5
Number of full sisters	1.1	1.4	3.7	-1.2	-0.9	-1.3	-1.9	-1.7	-1.2	-1.3	0.6	-0.1	-1.1	-1.1	-1.0	-1.3	-1.0	-1.4	-1.2	-1.4	-1.0
Ever had prostate specific antigen (PSA) test	1.1	1.3	7.8	-0.8	-1.2	-1.1	-0.2	2.8	-0.0	-1.4	-1.5	-0.6	-1.0	-0.8	-0.6	-1.2	-1.5	-0.7	-0.9	-1.1	-0.9
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	6.8	-1.0	-0.1	-0.9	-0.4	2.6	-1.4	-0.2	-1.9	-0.4	-0.9	-0.6	-1.2	-1.0	1.3	-1.5	-1.4	-0.8	0.7
Verbal and Numeric Reasoning (VNR)	1.0	2.4	5.4	1.0	-1.0	1.5	-0.4	-1.1	2.0	0.7	1.9	1.2	1.7	1.8	2.1	1.5	-2.2	2.2	2.3	1.4	-0.7
Cardiovascular Disease	1.0	3.4	7.3	1.8	1.6	1.8	1.2	2.4	0.9	1.8	1.6	2.7	1.9	2.1	2.1	1.8	1.6	1.7	1.8	1.8	2.4
Nervous feelings	1.0	1.9	4.8	1.5	1.4	1.3	1.3	-1.4	1.3	1.3	-0.3	2.1	1.1	1.7	1.2	1.3	1.9	1.1	1.3	1.1	2.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.2	5.5	1.4	1.6	2.2	1.6	-1.2	1.6	2.2	1.9	0.7	1.7	2.1	2.2	2.4	2.0	2.0	2.2	2.0	1.4
Pulse wave peak to peak time	1.0	1.2	8.2	-0.7	-0.2	-0.8	-0.9	-0.7	-0.9	-0.5	0.8	-2.9	-0.6	-1.3	-1.8	-0.8	-0.5	-1.2	-1.3	-0.6	-0.9
Angina (self-reported)	1.0	1.3	6.2	0.6	0.8	1.2	0.4	0.0	0.6	2.5	0.7	1.0	1.2	1.2	0.6	1.0	1.6	1.0	0.9	2.0	0.8
Arm fat percentage (left)	1.0	3.9	10.6	-1.8	-0.8	-2.1	-0.2	3.3	-2.0	-1.9	-2.5	-2.0	-2.2	-2.1	-2.2	-2.4	0.5	-2.3	-2.4	-2.2	-0.6
Depressed Affect (Nagel 2018)	0.9	2.0	4.1	-1.6	-1.3	-1.9	-0.5	-0.3	-1.3	-1.3	-1.8	-0.1	-1.8	-1.4	-1.2	-2.0	0.8	-1.9	-1.8	-1.8	-0.9
Crohns Disease (2012)	0.9	1.4	3.6	1.7	0.0	1.6	1.3	-0.1	1.3	0.9	0.0	0.0	1.5	1.3	1.2	1.9	0.0	1.4	1.6	1.1	1.4
Blood Eosinophil Count	0.9	6.6	11.0	3.3	3.2	3.1	2.1	0.2	3.0	2.0	2.8	2.3	2.7	2.9	2.6	3.3	1.1	2.6	2.9	2.4	3.0
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	6.2	0.9	0.6	0.7	-0.1	-0.7	0.7	0.8	2.5	1.7	0.9	1.3	1.3	0.4	1.3	0.8	0.7	0.6	1.2
Impedance of leg (left)	0.9	4.3	19.7	-1.0	-0.1	-2.3	-3.1	-4.4	-1.9	-2.7	-0.8	-0.8	-2.2	-1.9	-1.8	-1.8	-0.5	-2.4	-2.2	-2.7	0.1
Had other major operations	0.9	1.1	3.0	-0.8	-1.5	-1.3	-1.2	1.3	0.1	-1.7	-0.6	0.1	-1.1	-1.0	-0.1	-1.1	-1.2	-0.9	-0.7	-1.5	-1.2
Pain all over the body in last month	0.9	1.0	2.2	-0.9	-0.9	-1.2	-1.0	0.4	-0.8	-1.4	-1.4	-1.0	-1.2	-1.0	-0.8	-1.0	-0.0	-1.1	-0.9	-1.5	-0.6
Falls in the last year	0.9	1.3	8.9	-1.3	-0.6	-0.9	0.4	3.0	-0.6	0.2	-1.1	0.5	-0.5	-0.6	-0.5	-1.1	2.2	-1.4	-1.0	-0.7	-0.3
Pulse wave reflection index	0.9	1.1	4.0	1.1	0.7	1.1	0.5	0.3	0.9	1.1	0.8	2.0	1.3	1.2	1.2	1.1	1.1	1.0	1.3	1.0	1.0
Qualifications: O levels/GCSEs or equivalent	0.9	1.4	7.4	0.3	0.3	1.4	-0.4	-2.7	0.2	1.4	1.6	0.7	1.5	1.0	1.0	1.6	-0.3	1.1	1.5	1.4	-0.3
Number of full brothers	0.9	1.1	9.1	-0.5	0.0	-1.0	0.6	3.0	-0.3	-1.1	-0.4	0.7	-1.1	-0.5	-0.2	-0.8	1.0	-1.2	-0.9	-1.4	0.8
Number of children fathered	0.9	1.0	2.3	-0.9	-0.2	-1.0	0.3	1.5	-1.0	-1.3	0.4	-1.5	-1.4	-1.2	-0.9	-1.0	-0.5	-1.3	-1.3	-1.3	-0.3
Supplements: Vitamin C	0.9	1.1	2.5	0.3	-0.4	1.1	0.2	1.2	0.8	1.5	1.4	0.9	0.9	0.9	1.2	1.2	0.9	1.3	1.6	1.3	-0.7
Risk taking	0.9	1.3	3.9	-1.2	-0.9	-1.1	-0.8	1.6	-0.7	-2.0	-1.2	-1.1	-1.7	-1.3	-0.6	-0.5	-1.3	-0.9	-0.6	-1.6	-1.0
Alzheimer’s Disease (in mother)	0.8	0.9	3.0	-1.1	-0.5	-0.7	-1.3	-1.1	-1.6	0.1	0.3	-1.7	-0.7	-0.8	-1.3	-0.8	0.9	-1.0	-1.0	-0.5	-0.7
Fasting Glucose	0.8	1.0	4.5	-1.6	-1.3	-0.5	-0.3	0.4	-1.6	0.0	-2.1	0.0	-0.9	-1.1	-1.0	-0.7	-0.4	-0.6	-0.4	-0.2	-1.6
Blood Red Count	0.8	7.5	26.5	3.2	3.8	2.6	2.1	5.2	1.8	1.2	1.1	2.5	1.5	2.8	3.1	2.8	1.9	1.9	2.3	1.5	5.1
Chronotype (morning person)	0.8	1.9	7.9	1.6	2.5	1.1	2.8	2.3	0.3	0.4	0.0	0.4	0.9	1.0	0.8	1.1	1.3	0.5	0.7	0.4	2.6
Other serious medical condition/disability diagnosed by doctor	0.8	1.1	3.4	-0.6	-1.1	-1.3	-0.9	0.1	-0.1	-1.8	-1.4	-0.3	-1.1	-1.1	-0.7	-0.8	-1.0	-1.2	-0.8	-1.7	-0.9
Supplements: Zinc	0.8	0.9	3.4	-1.2	-1.7	-0.9	-0.8	1.4	-0.8	-0.5	0.5	0.0	-0.5	-0.6	-0.4	-1.1	-1.4	-0.5	-0.5	-0.4	-1.8
Impedance of leg (right)	0.8	3.6	15.7	-0.8	0.0	-2.0	-2.8	-4.0	-1.7	-2.8	-0.6	-0.9	-2.1	-1.7	-1.7	-1.5	-0.7	-2.2	-2.0	-2.6	0.2
Taking other prescription medications	0.8	1.3	12.0	-0.9	-0.9	-1.2	-0.4	3.5	-0.6	-0.8	-1.3	0.3	-1.0	-0.8	-0.5	-0.9	0.5	-1.1	-1.0	-1.1	-0.4
Medication: Atenolol	0.8	1.0	2.5	1.1	1.3	1.2	0.6	-0.1	1.0	1.5	-0.3	0.8	1.0	1.0	0.7	1.2	0.9	0.9	1.0	1.4	1.6
Body mass index (BMI)	0.8	3.5	15.7	-1.7	-0.5	-1.6	0.7	4.0	-1.9	-0.9	-2.5	-2.4	-1.7	-1.9	-2.3	-2.1	0.7	-2.0	-2.2	-1.4	-0.6
Worrier / anxious feelings	0.8	1.6	3.4	1.3	0.8	1.4	0.3	-0.5	1.1	1.3	0.7	1.6	1.2	1.9	1.6	1.7	0.7	1.3	1.8	1.3	1.5
Headache pain in last month	0.8	1.4	3.3	-1.0	-0.5	-1.4	-0.3	1.8	-0.7	-1.6	-1.6	-0.7	-1.5	-1.3	-0.9	-1.3	0.6	-1.6	-1.3	-1.8	-0.5
Overall health rating	0.8	1.8	4.2	-1.7	-1.3	-1.6	-0.3	1.8	-1.5	-0.4	-2.1	-0.2	-1.2	-1.2	-1.4	-2.0	0.7	-1.7	-1.7	-1.0	-0.8
Qualifications: nursing, teaching	0.8	1.3	7.0	0.7	0.3	1.2	-0.2	0.6	1.3	1.1	2.6	0.6	1.1	0.9	1.2	1.6	-0.3	1.2	1.5	1.2	-0.2
Medication for cholesterol	0.8	1.2	2.4	-1.4	-0.5	-1.2	-0.2	-1.2	-1.3	-0.6	-0.5	-1.5	-1.3	-1.3	-1.4	-1.4	0.5	-1.4	-1.5	-1.0	-1.1
Ever depressed for a whole week	0.8	1.0	11.7	0.7	0.5	0.1	0.8	3.4	0.9	-1.0	0.2	-0.0	-0.4	-0.0	0.4	0.9	-1.2	0.1	0.5	-0.5	0.7
Intelligence (Savage-Jansen 2018)	0.7	2.2	7.9	0.7	-1.2	1.3	-1.5	-1.0	1.5	0.4	1.9	0.8	1.5	1.6	1.9	1.1	-2.8	2.1	2.1	1.2	-1.1
Breast Cancer	0.7	1.7	5.0	-1.5	-2.2	-1.3	-0.9	1.1	-0.8	-1.3	-1.3	-1.6	-1.1	-1.4	-0.8	-1.2	-1.8	-0.7	-0.7	-1.1	-2.2
Systolic Blood Pressure	0.7	3.5	7.6	1.6	1.6	2.1	2.8	2.0	1.0	2.3	0.1	1.9	1.6	2.0	2.1	2.2	1.6	2.0	2.0	2.2	2.0
Angina	0.7	1.0	5.1	0.5	0.7	1.1	0.2	0.0	0.5	2.3	0.4	0.8	1.0	0.9	0.4	0.8	1.4	0.9	0.7	1.9	0.6
Qualifications: CSEs or equivalent	0.7	0.9	2.2	-1.1	-1.0	-1.0	-0.3	-0.2	-0.9	-0.5	-1.5	-0.9	-0.8	-1.2	-1.2	-1.2	-0.1	-1.0	-1.0	-0.7	-1.5
Had menopause	0.7	0.9	2.7	1.2	0.7	0.9	-0.2	1.1	1.5	0.2	1.6	1.2	0.7	0.8	1.2	1.0	-0.6	1.1	1.1	0.6	0.7
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	3.6	-0.1	0.6	-0.8	0.5	1.9	-0.4	-1.3	-0.8	0.0	-1.4	-0.5	-0.3	-0.2	1.3	-1.0	-0.6	-1.5	1.2
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	5.4	-1.3	-2.3	-1.4	-1.3	-0.4	-0.9	-0.7	0.4	-0.3	-0.4	-1.0	-1.2	-1.4	-1.0	-0.8	-1.2	-0.8	-2.0
Emphysema/chronic bronchitis	0.7	0.8	2.5	-0.7	-0.4	-0.9	-1.6	-0.3	-1.0	-0.9	0.7	-1.2	-0.7	-1.1	-1.2	-0.9	0.1	-1.2	-1.0	-1.1	-0.4
Medication: Omeprazole	0.7	0.8	7.8	-0.5	0.2	-0.4	0.0	2.8	-0.9	0.2	-0.9	0.1	-0.5	0.0	-0.4	-0.6	1.6	-0.8	-0.9	-0.3	1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	3.1	-0.8	0.3	-0.7	-0.4	1.8	-1.6	-0.3	0.0	-1.1	-0.8	-0.7	-0.9	-1.1	0.7	-1.0	-1.2	-0.6	0.3
Osteoporosis (self-reported)	0.7	0.8	2.6	-0.9	-1.0	-1.2	-1.0	-0.5	-0.5	-1.6	-0.1	0.7	-1.3	-0.7	0.0	-0.6	-1.1	-1.0	-0.4	-1.5	-0.7
Ever taken oral contraceptive pill	0.7	0.7	3.0	-0.5	-0.1	-0.7	-0.5	-1.1	-1.1	-1.0	-0.5	-1.7	-0.9	-1.1	-0.9	-0.4	-0.8	-0.7	-0.5	-0.9	-1.0
Mother’s age at death	0.7	0.9	4.0	-0.8	-1.1	-1.1	-2.0	-1.5	-0.5	-0.5	0.8	-0.2	-0.6	-1.2	-0.8	-1.1	0.1	-0.8	-1.1	-0.7	-1.2
BMI	0.6	3.3	12.5	-1.9	-0.4	-1.6	0.9	3.5	-2.0	-0.6	-2.9	-1.5	-1.7	-1.9	-2.2	-2.1	0.9	-2.3	-2.3	-1.2	-0.6
Hypothyroidism (self reported)	0.6	1.5	7.2	-1.4	-2.7	-1.4	-1.6	-0.3	-0.6	-0.8	0.4	0.0	-0.5	-1.0	-0.7	-1.3	-1.3	-0.6	-0.8	-0.8	-2.6
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	2.6	0.9	0.1	0.5	0.4	0.5	1.6	0.7	0.8	0.7	0.9	0.9	1.1	0.5	1.4	0.6	0.7	0.5	0.5
Pack years adult smoking proportion	0.6	1.0	2.8	-1.2	0.2	-0.9	0.5	1.6	-1.7	-0.3	-0.5	-0.1	-1.3	-0.8	-0.8	-1.1	1.3	-1.2	-1.4	-0.7	0.4
Relative age voice broke	0.6	0.9	4.9	0.8	1.6	0.8	0.1	-0.4	0.6	0.5	2.2	1.0	0.5	1.0	0.8	0.7	0.4	0.6	0.5	0.6	1.6
Hayfever, allergic rhinitis or eczema	0.6	1.4	4.6	-1.6	-1.9	-1.0	-0.6	1.6	-1.0	-0.3	-1.5	-1.2	-0.7	-1.2	-1.2	-1.1	-0.6	-0.8	-0.8	-0.5	-2.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	3.7	-0.6	-0.5	-0.5	-1.5	-0.0	-0.1	-1.6	-0.3	-0.5	-1.4	-0.6	0.1	-0.0	-1.9	-0.2	0.1	-1.0	-0.4
Chronic bronchitis/emphysema (father)	0.6	0.7	1.9	-1.1	-0.5	-1.0	-0.3	0.3	-0.9	-0.5	-0.4	-0.7	-1.0	-0.9	-0.8	-1.2	0.8	-1.4	-1.0	-1.0	-0.4
High blood pressure (mother)	0.6	0.9	2.8	0.5	-0.5	0.9	-0.3	-1.6	0.9	0.3	1.7	0.6	0.7	1.0	1.3	0.9	-1.1	1.1	1.4	0.7	-0.3
Waist circumference	0.6	2.3	25.9	0.9	1.3	0.9	2.2	5.1	0.4	1.0	-0.6	0.3	0.6	0.6	0.6	0.7	1.5	0.5	0.5	0.8	1.5
Hearing difficulty/problems with background noise	0.6	1.0	3.7	-0.4	-1.1	-1.1	-1.5	-0.8	0.1	-1.9	0.3	0.2	-1.1	-0.9	-0.4	-1.1	-1.3	-0.7	-0.6	-1.6	-0.8
Financial difficulties in last 2 years	0.6	0.8	2.6	-0.8	-0.2	-0.9	0.2	1.6	-1.0	-0.9	-1.3	-0.5	-1.0	-1.0	-1.0	-1.0	-0.1	-1.2	-1.1	-1.0	-0.4
Diabetes (self-reported)	0.6	0.9	2.4	1.1	0.8	1.0	0.1	0.2	1.3	0.1	0.2	1.4	0.2	0.8	1.5	1.5	0.8	1.4	1.5	0.4	1.1
Medication: Ramipril	0.6	0.8	4.0	0.7	0.2	0.8	-0.4	1.3	0.6	0.7	2.0	0.9	0.8	1.1	1.0	0.9	0.0	1.2	1.0	0.9	0.6
Noisy workplace	0.6	0.8	3.6	-0.4	-0.6	-1.1	-0.8	1.9	-0.4	-0.7	-0.6	-0.5	-0.3	-0.7	-0.3	-1.4	0.7	-1.1	-1.1	-1.1	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	4.9	-0.2	-0.6	0.8	1.7	2.2	0.4	0.8	-0.0	-0.2	0.5	0.6	0.8	0.5	-0.2	1.1	0.9	0.9	-1.1
Prospective memory result	0.6	0.8	3.2	0.4	0.0	0.9	-0.1	-1.3	0.0	1.8	0.7	0.2	1.2	1.1	0.5	0.5	1.0	0.8	0.8	1.5	0.7
Glaucoma (self-reported)	0.6	0.7	3.5	0.4	-0.4	0.3	-0.8	1.1	0.8	0.9	0.6	1.9	0.7	1.1	1.3	0.2	0.6	0.6	0.7	0.8	0.4
Body fat percentage	0.6	2.6	6.0	-1.1	-0.1	-1.8	-0.3	2.5	-1.7	-1.6	-2.1	-1.4	-1.8	-1.6	-1.8	-2.0	0.9	-2.1	-2.1	-2.0	0.4
Illnesses of siblings: Diabetes	0.6	0.7	2.4	-0.7	-0.5	-0.9	-0.7	0.4	-0.6	-0.9	-0.7	-1.5	-0.6	-1.0	-1.1	-0.9	-0.1	-1.1	-1.1	-1.1	-0.5
Loneliness, isolation	0.6	0.9	2.0	-0.9	-1.0	-1.1	-0.1	0.3	-0.6	-1.0	-0.9	-0.2	-0.9	-1.4	-0.9	-1.3	0.2	-1.3	-1.0	-1.2	-1.1
Ever had bowel cancer screening	0.6	0.7	1.9	-1.2	-0.2	-0.8	-1.0	1.0	-1.4	-0.7	-0.2	-1.1	-1.2	-0.8	-1.0	-0.6	0.4	-1.0	-1.0	-1.0	-0.2
Diabetes diagnosed by doctor	0.6	0.9	2.6	1.1	0.4	0.7	0.4	1.1	1.6	-0.3	-0.5	1.4	0.1	0.9	1.6	1.2	0.5	1.3	1.3	0.1	1.1
Mineral and other dietary supplements	0.6	0.8	5.7	0.8	1.7	0.7	0.8	-0.2	0.1	1.0	-0.0	-0.2	0.6	0.4	-0.1	0.4	2.4	0.3	0.1	0.6	1.3
Number of self-reported non-cancer illnesses	0.6	1.0	4.4	-0.8	-1.6	-1.2	-0.9	2.1	-0.4	-1.2	-0.8	-0.1	-1.0	-1.0	-0.5	-0.8	-0.6	-0.7	-0.7	-1.1	-1.1
Supplements: Fish oil (including cod liver oil)	0.6	0.8	1.6	-0.7	-0.6	-0.9	-1.2	-0.3	-0.9	-1.2	0.1	-0.8	-0.8	-1.0	-1.0	-0.8	-1.3	-1.1	-0.9	-1.0	-0.7
Fractured/broken bones in last 5 years	0.6	0.7	2.0	-0.8	-0.7	-1.0	-1.2	-0.5	-1.1	-0.5	0.4	-0.3	-0.5	-0.8	-1.4	-1.2	-0.3	-1.4	-1.3	-0.8	-0.2
Supplements: Calcium	0.6	0.7	4.0	-1.0	-1.3	-0.4	-2.0	-0.6	-0.6	0.1	0.7	0.4	-0.3	-0.3	-0.0	-0.3	-1.6	-0.3	0.0	0.2	-1.1
Heart disease (siblings)	0.6	0.8	1.8	-0.7	-0.5	-0.9	0.6	1.1	-1.3	-1.4	-0.6	-0.7	-1.2	-0.9	-0.9	-0.7	-0.7	-0.8	-0.9	-1.2	-0.4
Body Mass Index (BMI) (2010)	0.5	0.7	3.1	-0.9	0.1	-0.5	0.1	1.3	-1.6	0.3	-0.4	0.0	-0.6	-0.5	-1.0	-0.6	1.8	-1.0	-0.9	-0.3	0.3
Ever used hormone-replacement therapy (HRT)	0.5	0.7	3.0	-0.6	-0.8	-0.8	-1.0	0.4	-0.1	-1.7	-0.8	-0.2	-1.5	-0.8	-0.0	-0.4	-1.1	-0.4	-0.2	-1.3	-0.3
Systolic blood pressure, automated reading	0.5	1.3	8.2	1.0	1.2	0.9	2.9	2.4	0.5	0.8	-0.2	0.3	0.7	0.7	0.8	0.9	1.3	0.7	0.6	0.7	1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	3.0	-0.9	-0.2	-0.9	0.5	0.3	-1.6	-0.6	-1.5	-1.7	-1.0	-1.2	-1.7	-0.7	0.5	-1.3	-1.1	-0.9	-0.7
Trunk fat mass	0.5	2.2	12.5	1.5	2.2	1.2	1.9	3.5	0.7	0.9	0.0	0.5	0.8	1.1	0.8	1.1	1.6	0.7	0.7	0.8	2.6
Mouth/teeth dental problems: Dentures	0.5	0.8	3.5	1.2	1.4	0.6	0.2	1.2	0.7	0.7	1.3	1.3	1.1	0.7	0.2	0.0	0.8	0.1	-0.2	0.5	1.9
Depression (self-reported)	0.5	0.6	2.6	1.0	1.1	0.8	0.4	0.9	0.5	0.3	0.5	0.8	0.8	0.9	0.7	0.9	0.3	0.6	0.7	0.5	1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.4	-0.7	-0.7	-1.0	0.7	1.4	-0.3	-1.6	-0.1	-0.6	-1.4	-0.5	-0.1	-0.9	-0.3	-0.7	-0.7	-1.4	0.0
Health satisfaction	0.5	0.6	2.0	0.9	0.2	0.4	0.6	1.3	1.4	-0.7	-0.7	0.5	-0.1	0.6	1.2	0.9	-1.1	0.6	1.1	-0.1	0.6
Leg pain on walking	0.5	0.6	2.3	0.5	-0.5	0.1	-0.5	0.5	1.0	0.5	0.8	1.2	0.6	1.0	1.5	0.2	1.4	0.4	0.6	0.2	0.8
Eye problems/disorders: Cataract	0.5	0.5	1.5	1.0	1.2	0.8	0.7	-0.3	0.7	0.4	0.4	0.9	0.9	0.9	0.9	0.6	0.3	0.6	0.5	0.5	1.2
Eye problems/disorders: Glaucoma	0.5	0.6	1.7	0.9	0.0	0.4	-0.7	0.0	1.3	0.5	1.2	1.1	0.9	0.9	1.0	0.4	-0.4	0.8	0.6	0.7	0.5
Irritability	0.5	0.8	2.0	-0.5	1.0	-0.4	0.9	-1.1	-1.3	-0.9	-0.9	-1.1	-1.4	-0.4	-0.5	-0.2	1.1	-0.8	-0.4	-1.1	0.9
Diastolic blood pressure, automated reading	0.5	1.4	5.5	1.3	1.9	1.3	2.3	0.8	0.3	1.1	0.5	0.5	0.9	1.0	0.8	1.2	1.7	0.5	0.9	0.8	1.9
Depression (Nagel 2018)	0.4	0.6	2.0	-1.1	-1.4	-0.9	0.2	1.0	-0.4	-0.8	-0.5	-0.4	-1.4	-0.8	-0.6	-0.8	-0.4	-0.4	-0.5	-0.8	-1.1
HDL Cholesterol	0.4	0.7	1.8	0.9	0.7	1.0	1.1	-0.8	1.3	0.4	1.0	0.0	0.7	0.8	1.3	0.8	-0.5	1.1	1.2	0.8	0.4
Neuroticism (2016)	0.4	0.6	3.0	0.5	0.1	0.4	1.3	0.3	1.2	0.5	0.5	1.7	0.3	0.8	1.1	0.3	1.1	0.6	0.7	0.3	0.6
Heel T-Score	0.4	3.3	10.7	-0.8	-0.1	-1.8	0.1	-1.7	-2.2	-2.6	-1.0	-3.3	-1.7	-2.2	-2.5	-1.4	-1.0	-1.7	-2.2	-2.4	-1.2
Number of treatments/medications taken	0.4	0.7	6.7	-0.5	-1.2	-0.8	-0.6	2.6	0.1	-0.6	-0.8	0.7	-0.4	-0.3	0.2	-0.8	-0.2	-0.5	-0.5	-0.6	-0.4
Hearing difficulty/problems: Yes	0.4	0.6	2.2	0.7	-0.4	-0.4	-0.1	1.4	1.3	-1.3	-0.8	0.6	-0.2	0.0	0.7	-0.5	-1.5	0.2	-0.0	-0.7	0.3
Relative age of first facial hair	0.4	0.8	3.5	1.1	1.4	0.8	1.9	-0.1	1.3	-0.0	1.1	-0.4	0.4	0.7	0.7	1.3	-0.1	0.7	0.8	0.3	1.0
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.1	0.6	0.7	0.7	0.6	1.0	0.5	0.5	-0.4	0.5	0.3	0.7	0.8	1.0	0.7	0.6	0.9	0.5	0.9
Medication: Levothyroxine sodium	0.4	0.7	1.8	-0.6	-1.3	-1.1	-1.1	-0.3	-0.6	-1.0	-0.1	-0.6	-0.5	-1.0	-1.0	-1.0	-0.8	-0.6	-1.0	-0.9	-1.2
Heart attack	0.4	0.5	1.4	-0.8	-1.0	-0.7	-1.0	0.9	-0.4	-0.1	0.6	-0.7	-0.7	-0.8	-0.7	-0.7	0.2	-0.3	-0.7	-0.2	-1.2
Hair/balding pattern: Pattern 3	0.4	0.6	2.0	0.8	1.4	0.8	-0.9	-0.9	-0.4	1.1	0.3	0.8	1.0	0.9	-0.1	0.5	0.5	0.0	0.1	0.9	1.4
Number of live births	0.4	0.6	5.0	-1.0	-1.2	-0.5	-0.4	2.2	-0.5	0.0	-0.7	0.1	-0.4	-0.6	-0.3	-0.8	-0.4	-0.2	-0.5	-0.0	-1.2
Lung cancer (father)	0.4	0.4	1.6	0.5	0.8	0.6	0.7	-0.3	0.5	0.6	-0.4	0.4	0.6	0.8	0.8	0.5	1.3	0.4	0.6	0.4	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.5	-0.7	-1.0	-0.8	-0.2	1.6	-0.3	-1.3	-0.6	0.3	-1.2	-0.4	0.0	-0.5	-1.0	-0.5	-0.2	-1.1	-0.2
Birth weight	0.4	0.9	6.6	-1.1	-0.7	-0.2	-2.6	-2.0	-1.2	0.2	0.9	-0.8	-0.3	-0.3	-0.7	-0.6	0.4	-0.5	-0.5	-0.1	-0.8
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.5	-1.0	-0.1	-0.5	-0.1	-0.6	-1.1	-0.2	-1.2	-0.3	-0.7	-1.0	-1.1	-0.4	-0.4	-0.8	-0.5	-0.3	-0.8
Medication for pain relief, constipation, heartburn	0.4	0.6	5.2	0.8	1.1	0.4	0.4	-2.3	0.4	-0.6	0.1	-0.2	-0.3	-0.1	-0.0	1.0	-1.3	0.4	0.5	-0.0	0.5
Medication: Ibuprofen	0.4	0.4	4.3	-0.4	-0.6	0.0	1.2	2.1	-0.1	-0.0	-0.4	-0.6	-0.2	-0.1	0.1	-0.1	-0.1	0.2	0.0	-0.0	-1.0
Leg fat mass (right)	0.4	1.5	11.8	-0.2	0.9	-0.4	1.3	3.4	-1.0	-0.1	-1.2	-1.5	-0.6	-0.6	-1.2	-0.8	1.1	-1.1	-1.3	-0.5	1.1
Commuting to job workplace: Car/motor vehicle	0.4	0.5	3.6	0.1	0.6	0.1	1.7	1.9	0.2	-0.2	0.5	0.4	-0.5	-0.2	0.1	0.1	0.9	-0.1	0.0	-0.2	0.4
Average weekly beer plus cider intake	0.4	0.5	2.2	0.8	0.3	0.3	1.2	1.1	0.8	-0.4	-1.5	0.3	0.3	0.7	0.7	0.6	-0.7	0.4	0.6	-0.1	0.7
Age started oral contraceptive pill	0.4	0.5	1.3	1.2	1.0	0.6	0.9	-0.5	0.8	0.3	-0.9	0.5	0.6	0.3	0.4	1.1	-0.3	0.7	0.6	0.6	1.0
Myopia	0.4	0.6	4.3	-0.2	0.6	0.4	0.1	-1.3	-1.1	1.1	-0.5	1.5	-0.1	0.2	0.0	0.6	2.1	-0.0	0.3	0.5	0.4
Heart attack/myocardial infarction (self-reported)	0.4	0.6	1.5	-0.8	-0.8	-0.8	-1.0	1.2	-0.4	-0.2	0.9	-0.6	-0.7	-0.9	-0.8	-0.7	0.1	-0.5	-0.8	-0.3	-1.1
Pack years of smoking	0.4	0.5	3.1	-0.6	0.6	-0.3	0.8	1.8	-1.1	0.1	-0.1	0.3	-0.7	-0.4	-0.2	-0.5	1.2	-0.6	-0.7	-0.2	0.7
Bipolar Disorder (2018)	0.3	0.5	2.5	0.1	0.7	0.5	1.1	1.4	0.3	0.8	-0.0	0.0	-0.0	0.7	0.6	0.6	1.6	0.2	0.4	0.5	1.1
Lupus	0.3	0.4	1.8	1.0	0.2	0.4	-0.7	-1.2	1.3	0.3	1.0	0.2	0.9	0.2	0.6	0.4	0.1	0.6	0.6	0.4	-0.1
Primary Biliary Cirrhosis	0.3	0.5	1.8	0.2	0.5	-0.6	-0.0	0.8	-0.3	-1.3	-1.1	-1.0	-0.6	-0.7	-0.6	-0.2	-0.8	-0.7	-0.6	-1.1	0.4
Blood White Count	0.3	1.9	3.8	-1.2	-1.4	-1.8	-1.0	0.4	-1.2	-1.3	-1.9	-1.0	-1.2	-1.4	-1.6	-1.9	-0.8	-1.7	-1.9	-1.4	-0.7
Medication: Metformin	0.3	0.5	1.6	0.7	0.4	0.3	0.4	0.8	0.8	-0.6	-0.4	1.3	-0.3	0.6	1.2	0.7	0.2	0.7	0.7	-0.2	1.2
Trunk fat percentage	0.3	1.0	6.2	-0.0	0.8	-0.8	0.3	2.5	-0.6	-0.9	-1.3	-0.4	-0.9	-0.6	-0.7	-0.9	1.1	-1.0	-1.0	-1.1	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.5	0.5	-0.1	0.3	1.0	1.2	0.9	-0.0	-0.4	0.9	0.3	0.7	1.0	0.1	0.7	0.5	0.6	-0.0	0.7
Mouth/teeth dental problems	0.3	0.5	2.1	0.1	0.7	0.8	1.3	0.1	0.1	0.9	0.2	0.0	0.2	0.6	0.7	1.1	1.4	0.6	0.9	0.7	0.4
Neuroticism score	0.3	0.6	4.1	0.4	0.8	0.3	0.8	0.1	0.1	0.4	-1.0	1.1	0.1	0.7	0.5	0.4	2.0	-0.2	0.4	-0.1	1.6
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.8	0.7	0.8	0.6	0.1	-0.6	0.2	-0.1	1.4	0.4	0.3	0.4	0.4	0.6	-0.5	0.6	0.6	0.3	0.7
Impedance of arm (left)	0.3	1.3	7.6	1.1	0.3	0.0	-1.1	-2.8	1.3	-1.0	1.5	2.1	0.2	0.8	1.5	0.6	-0.1	0.7	1.0	-0.6	0.8
Arm fat mass (right)	0.3	1.3	15.8	-0.2	0.6	-0.1	1.4	4.0	-0.5	-0.0	-1.2	-1.2	-0.4	-0.5	-0.8	-0.4	0.9	-0.5	-0.7	-0.2	0.6
Mouth/teeth dental problems: Bleeding gums	0.3	0.3	1.9	0.8	0.7	0.5	1.4	0.2	0.5	-0.0	-0.2	-1.0	0.1	0.2	0.2	0.8	-0.5	0.5	0.6	0.3	0.3
Medication: Paracetamol	0.3	0.5	3.5	-0.8	-0.9	-0.3	0.6	1.9	0.1	0.2	-0.1	-0.9	-0.1	-0.5	-0.4	-0.5	0.9	-0.3	-0.3	-0.2	-1.2
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	1.6	-0.4	-0.5	-0.7	-0.0	-0.2	-0.1	-1.2	-0.2	-1.0	-0.5	-0.9	-0.8	-0.6	-0.7	-0.7	-0.6	-1.2	-1.0
Whole body fat mass	0.3	1.3	13.0	0.7	1.5	0.4	1.6	3.6	-0.0	0.4	-0.4	-0.3	0.1	0.4	-0.0	0.2	1.4	-0.1	-0.1	0.2	1.9
Suffer from ‘nerves’	0.3	0.5	2.2	-0.4	0.4	-0.2	-0.6	-0.9	-0.8	0.1	-1.4	-0.1	-0.3	0.1	-0.5	-0.3	1.5	-0.9	-0.5	-0.4	1.2
Medication: Aspirin	0.3	0.3	1.4	0.1	-1.0	-0.1	-1.2	0.9	0.2	0.3	0.8	1.0	0.6	0.6	0.7	-0.4	-0.4	0.2	0.1	0.3	0.2
Illnesses of father: None of the above (group 1)	0.3	0.3	1.2	-0.2	-0.7	0.0	1.1	-0.9	0.3	0.5	0.1	-0.7	0.7	-0.1	-0.2	-0.6	-1.0	0.2	-0.3	0.6	-0.9
Arm fat mass (left)	0.3	1.4	16.7	-0.2	0.7	-0.1	1.3	4.1	-0.7	0.1	-1.1	-1.1	-0.3	-0.4	-0.8	-0.4	1.2	-0.6	-0.7	-0.2	0.8
Guilty feelings	0.3	0.4	1.7	-0.3	-0.6	-0.8	-1.0	0.1	-0.4	-0.7	0.2	0.1	-0.8	-0.4	-0.2	-0.5	1.3	-0.8	-0.4	-1.1	0.1
Commuting to job workplace: Public transport	0.3	0.4	5.6	-0.1	0.0	0.0	-0.9	-2.4	-0.4	-0.3	0.1	-0.6	-0.4	-0.2	-0.2	0.2	-0.3	0.2	0.1	-0.1	-0.4
Medication: Paracetamol	0.3	0.4	4.0	-0.3	-0.5	-0.2	1.1	2.0	0.3	0.2	-0.4	-0.5	0.1	-0.3	-0.2	-0.4	1.1	-0.2	-0.4	-0.2	-0.7
Illnesses of father: High blood pressure	0.3	0.4	1.5	0.2	-0.5	0.2	-1.0	0.9	0.3	0.1	-1.2	1.1	0.3	0.3	0.4	0.5	-0.8	0.5	0.6	0.3	-0.3
Alcohol drinker status: Never	0.3	0.4	0.8	0.5	0.7	0.9	0.3	-0.3	0.5	0.9	0.3	0.8	0.6	0.5	0.2	0.7	0.4	0.7	0.6	0.9	0.6
Cholesterol lowering medication	0.3	0.4	1.5	-0.2	-0.5	-0.7	-1.2	0.8	-0.0	-1.1	-1.0	0.4	-0.6	-0.4	-0.2	-0.5	-0.1	-0.6	-0.4	-1.0	0.1
Impedance of whole body	0.3	1.5	16.3	0.7	0.6	-0.7	-1.9	-4.0	0.2	-1.6	0.5	1.1	-0.5	-0.1	0.2	-0.1	-0.2	-0.4	-0.2	-1.3	1.0
Leg fat mass (left)	0.3	1.4	11.0	-0.1	1.1	-0.3	1.3	3.3	-1.0	0.0	-1.1	-1.3	-0.5	-0.5	-1.1	-0.7	1.3	-1.0	-1.2	-0.3	1.2
Irritable Bowel Disease (IBD)	0.2	0.5	2.2	0.7	1.3	0.6	1.5	0.8	-0.0	0.6	0.3	-0.3	0.4	0.3	0.0	1.0	1.1	0.3	0.5	0.5	0.8
Ovarian Cancer	0.2	0.3	2.4	0.7	1.6	0.5	0.8	0.5	-0.0	0.4	-0.2	0.2	0.1	0.0	0.1	0.5	0.5	0.1	0.2	0.4	0.9
Rheumatoid Arthritis	0.2	0.3	1.4	-0.1	0.5	0.4	-0.4	-1.2	-0.6	0.7	0.6	-0.5	0.2	-0.1	-0.7	0.5	0.5	0.2	0.1	0.6	-0.0
Triglycerides	0.2	0.3	0.7	-0.1	0.2	-0.6	-0.7	-0.7	-0.8	-0.8	0.4	0.0	-0.5	-0.5	-0.7	-0.5	-0.7	-0.7	-0.7	-0.7	0.3
Lung FEV1/FVC ratio	0.2	1.0	3.1	0.6	1.5	1.2	0.9	-0.3	0.2	1.8	0.2	0.8	0.8	1.2	0.4	0.7	1.3	0.8	0.4	1.6	1.7
Neuroticism	0.2	0.5	2.9	0.1	0.1	-0.2	0.8	0.5	0.2	0.0	-1.4	1.0	-0.4	0.5	0.7	-0.1	1.7	-0.1	0.3	-0.3	1.0
Hair Pigment	0.2	5.1	11.4	1.8	1.9	2.6	2.2	1.6	1.2	3.4	1.3	2.6	2.3	2.5	2.5	2.3	3.0	2.3	2.3	2.9	1.9
Frequency of depressed mood in last 2 weeks	0.2	0.2	1.5	-0.1	-0.5	-0.1	1.0	1.2	0.0	-0.1	-0.6	-0.5	-0.3	-0.4	-0.1	0.1	0.3	0.0	0.3	-0.1	-0.5
Medication for hormone replacement therapy	0.2	0.2	1.5	0.4	0.0	-0.2	0.7	1.2	0.6	-0.5	-0.0	0.8	-0.1	0.1	0.5	-0.2	-0.7	0.2	-0.1	-0.2	0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	2.0	-0.6	-0.3	-0.4	-0.5	1.4	-0.5	-0.3	-0.7	-0.1	-0.5	-0.6	-0.5	-0.3	-0.5	-0.5	-0.5	-0.4	-0.2
Impedance of arm (right)	0.2	1.1	10.4	0.5	0.1	-0.5	-1.2	-3.2	0.7	-1.5	1.1	1.3	-0.4	-0.1	0.6	0.2	-0.6	0.0	0.3	-1.1	0.1
Illnesses of mother	0.2	0.2	0.9	-0.5	0.1	-0.5	0.9	0.4	-0.6	-0.1	-0.8	0.1	-0.3	-0.2	-0.3	-0.4	0.6	-0.6	-0.6	-0.4	0.2
Birth weight of first child	0.2	0.4	2.6	0.4	-0.0	0.4	1.1	1.1	0.7	0.6	0.2	-0.1	0.5	0.1	0.1	0.1	1.6	0.8	0.2	0.4	-0.4
Worry too long after embarrassment	0.2	0.3	1.4	0.5	0.1	0.2	1.2	0.8	0.7	0.5	-0.4	0.6	0.6	0.6	0.3	0.2	1.1	0.1	0.4	0.2	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	0.9	-0.5	-0.1	-0.6	-0.3	0.8	-0.4	-0.3	-0.6	-0.3	-0.4	-0.2	-0.2	-1.0	0.6	-0.8	-0.8	-0.6	0.3
Migraine (self-reported)	0.2	0.2	1.6	-0.3	-0.9	-0.1	0.6	1.3	0.5	-0.3	0.1	0.1	-0.1	-0.0	0.3	0.2	-0.4	0.4	0.4	-0.1	-0.7
Medication: Seretide 50 evohaler	0.2	0.2	1.7	-0.3	-0.8	-0.3	-0.2	0.5	-0.1	-0.3	-1.3	-0.0	-0.2	-0.2	-0.2	-0.5	-0.2	-0.3	-0.1	-0.3	-0.7
Medication: Aspirin	0.2	0.3	2.4	-0.1	-1.2	-0.5	-1.5	0.7	-0.0	0.2	0.2	0.7	0.4	0.2	0.3	-0.7	-0.3	-0.2	-0.3	0.0	-0.2
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.2	0.2	-0.3	-0.1	0.2	-1.1	0.4	-0.6	0.9	1.0	0.1	0.1	0.1	-0.1	-1.0	-0.1	0.1	-0.3	-0.2
Mood swings	0.2	0.3	3.3	-0.4	0.2	-0.3	0.5	0.7	-0.5	-0.1	0.5	0.1	-0.5	0.0	0.1	-0.3	1.8	-0.7	-0.2	-0.6	0.6
Medication: Gliclazide	0.2	0.3	1.4	-0.3	-1.2	-0.5	-1.0	0.4	-0.2	-0.4	-0.0	-0.5	-0.4	-0.4	0.3	-0.6	-0.1	0.1	-0.2	-0.4	-0.8
High cholesterol (Self-reported)	0.2	0.4	3.8	1.0	0.5	0.1	-0.5	2.0	0.4	-0.2	-0.1	0.3	0.3	0.2	0.2	0.5	0.9	0.2	0.3	-0.1	1.0
Medication: Atorvastatin	0.2	0.3	2.6	0.6	0.5	0.0	0.2	1.6	0.1	0.2	-0.4	0.9	0.6	0.4	0.1	-0.3	0.7	-0.2	-0.1	-0.1	0.8
Basal cell carcinoma (self-reported)	0.2	0.2	0.8	-0.4	0.1	-0.4	0.2	-0.9	-0.2	-0.7	-0.2	0.3	-0.5	-0.3	-0.2	-0.6	-0.5	-0.4	-0.6	-0.5	0.3
Neuroticism (Nagel 2018)	0.1	0.3	1.8	-0.1	-0.1	-0.4	0.2	-0.3	-0.1	-0.2	-0.6	1.4	-0.5	0.4	0.3	-0.3	1.2	-0.3	-0.1	-0.5	0.9
Crohns Disease (2017)	0.1	0.3	1.6	0.7	1.3	0.5	1.0	-0.4	-0.1	0.3	-0.2	-0.2	0.3	0.1	-0.0	0.9	0.8	0.1	0.3	0.3	0.9
Ulcerative Colitis (UC)	0.1	0.1	1.1	0.1	0.2	-0.1	1.1	1.0	0.0	0.0	0.3	-0.1	-0.0	-0.1	-0.1	0.3	0.2	-0.1	0.1	0.0	-0.1
Ulcerative Colitis	0.1	0.1	0.6	0.3	0.2	-0.3	0.8	-0.0	0.2	-0.3	0.1	0.0	0.1	0.1	0.0	-0.4	0.7	-0.2	-0.3	-0.4	0.3
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.6	-0.3	-0.3	-0.4	-0.7	-0.2	-0.2	-0.6	-0.7	0.4	-0.8	-0.4	-0.1	-0.1	0.8	-0.2	-0.2	-0.7	0.2
Tanning	0.1	1.8	9.2	1.0	2.5	1.0	3.0	2.5	0.7	0.3	0.5	0.2	0.1	1.0	0.6	1.3	0.1	0.5	0.5	0.6	2.5
Hand grip strength (left)	0.1	0.4	2.0	0.3	0.8	0.7	1.1	-0.0	-0.5	0.8	0.4	-1.4	0.3	0.1	-0.2	0.7	0.7	0.4	0.2	0.7	-0.1
Diabetes (mother)	0.1	0.1	0.6	0.2	0.1	-0.2	-0.6	-0.8	0.5	-0.5	-0.1	-0.1	-0.1	-0.3	-0.3	-0.2	0.5	-0.1	-0.2	-0.5	0.2
Hand grip strength (right)	0.1	0.4	1.8	-0.1	0.7	0.3	-0.7	-1.1	-1.3	0.5	0.2	-1.4	0.1	-0.3	-0.7	0.5	0.6	-0.1	-0.2	0.3	-0.3
Average weekly fortified wine intake	0.1	0.2	1.5	0.3	0.2	-0.0	1.2	-0.1	0.3	0.1	-0.4	-0.6	-0.0	0.2	0.0	-0.2	0.6	0.2	-0.1	0.1	0.5
Medication: Simvastatin	0.1	0.2	0.7	0.3	-0.2	-0.0	-0.8	0.8	0.5	0.1	-0.5	0.7	-0.0	0.2	0.4	0.4	0.4	0.2	0.3	0.2	0.4
Medication: Cholesterol lowering	0.1	0.2	0.6	0.2	0.1	0.3	-0.4	0.1	0.0	0.7	-0.6	0.8	0.2	0.5	0.5	0.2	0.8	0.4	0.3	0.6	0.6
Medication: Lansoprazole	0.1	0.2	0.7	0.3	0.1	0.3	0.2	0.2	0.9	0.0	0.3	0.7	0.1	0.2	0.4	0.6	0.2	0.5	0.7	0.1	0.3
Hair/balding pattern: Pattern 4	0.1	0.3	1.5	-0.3	-1.2	0.2	0.0	0.2	0.0	0.8	-0.9	0.9	0.3	0.6	0.7	0.0	0.7	0.6	0.6	0.6	-0.5
Eye problems/disorders: None of the above	0.1	0.2	0.6	-0.6	-0.3	0.1	0.1	-0.6	-0.5	0.5	-0.6	-0.2	-0.1	-0.3	-0.6	0.1	0.4	0.1	0.0	0.3	-0.8
Family relationship satisfaction	0.1	0.1	0.4	-0.0	0.7	0.4	-0.2	-0.4	-0.4	0.0	-0.2	0.4	-0.5	0.1	0.1	0.6	-0.3	0.2	0.4	0.2	0.4
Average weekly red wine intake	0.1	0.1	1.2	0.3	0.1	-0.0	-0.6	-0.1	-0.2	0.1	0.6	-1.1	0.4	-0.2	-0.3	-0.2	0.2	-0.1	-0.5	-0.1	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	3.0	-0.2	-0.5	0.0	0.4	-1.7	0.6	-0.4	-0.6	-0.5	-0.4	0.0	0.5	0.4	-0.5	0.4	0.5	-0.1	-0.5
Schizophrenia vs Biploar Disorder	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Waist Hip Ratio (WHR)	0.0	0.2	1.4	0.0	-0.0	0.1	-0.1	0.4	0.1	0.7	-0.7	1.2	0.2	0.1	0.5	-0.1	1.0	-0.1	0.0	0.3	0.5

Hub : Genes

RHBDL1

Models

Trait associations