TWAS hub - RHNO1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.2760	0.0540	6.5e-09	0.152	NA	0.117	NA	0.132	2.0e-12	NA	8.8e-10	NA	5.9e-11
2	GTEx	Artery Aorta	0.1780	0.0570	1.1e-03	0.109	NA	0.067	NA	0.083	1.4e-06	NA	1.5e-04	NA	2.4e-05
3	GTEx	Breast Mammary Tissue	0.1310	0.0480	3.8e-03	0.102	NA	0.060	NA	0.086	6.6e-06	NA	4.9e-04	NA	3.5e-05
4	GTEx	Breast Mammary Tissue (Female)	0.0804	0.0914	2.4e-01	-0.010	NA	-0.009	NA	-0.010	9.0e-01	NA	8.4e-01	NA	9.9e-01
5	GTEx	Cells Transformed fibroblasts	0.3190	0.0580	2.3e-10	0.196	NA	0.185	NA	0.188	1.1e-14	NA	7.6e-14	NA	4.6e-14
6	GTEx	Esophagus Mucosa	0.3250	0.0580	4.4e-10	0.263	NA	0.255	NA	0.250	1.0e-17	NA	3.7e-17	NA	8.1e-17
7	GTEx	Esophagus Muscularis	0.2100	0.0650	2.1e-04	0.010	NA	0.027	NA	0.038	7.9e-02	NA	8.8e-03	NA	2.3e-03
8	GTEx	Lung	0.0973	0.0398	8.1e-03	0.055	NA	0.027	NA	0.045	4.8e-05	NA	3.4e-03	NA	2.4e-04
9	GTEx	Nerve Tibial	0.1973	0.0561	3.1e-05	0.072	NA	0.101	NA	0.098	8.0e-06	NA	1.3e-07	NA	1.9e-07
10	GTEx	Skin Not Sun Exposed Suprapubic	0.2130	0.0680	1.2e-03	0.044	NA	0.056	NA	0.051	1.8e-03	NA	4.9e-04	NA	8.9e-04
11	GTEx	Skin Sun Exposed Lower leg	0.2160	0.0450	6.0e-09	0.140	NA	0.165	NA	0.159	1.1e-11	NA	1.4e-13	NA	3.9e-13
12	METSIM	Adipose	0.0791	0.0239	3.3e-05	0.060	0.015	0.039	0.039	0.047	2.2e-09	0.0022	1.5e-06	1.6e-06	1.3e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Chronic bronchitis/emphysema (father)	5.8	6.7	10.4	2.4	1.5	2.5	2.7	2.3	2.6	2.0	3.0	3.0	3.2	3.0	2.5
Mouth/teeth dental problems: Mouth ulcers	4.9	7.7	11.1	-2.8	-2.8	-3.2	-2.2	-2.8	-2.8	-2.0	-2.5	-3.3	-2.8	-3.1	-2.7
Breastfed as a baby	4.3	5.3	8.6	2.6	1.5	2.4	2.9	2.7	2.9	0.0	1.8	2.4	2.6	2.0	2.3
Chronic bronchitis/emphysema (mother)	3.8	4.5	9.7	1.8	1.6	3.1	1.7	2.0	2.0	2.4	2.0	1.7	2.0	2.6	1.9
Commuting to job workplace: Walk	3.8	4.1	8.8	2.0	2.3	3.0	0.9	1.6	1.6	2.2	1.2	2.1	2.2	2.7	1.8
Heart attack/myocardial infarction (self-reported)	3.8	4.9	8.9	1.9	2.8	2.1	0.7	2.0	2.0	2.5	1.8	2.6	3.0	2.4	2.0
Had menopause	3.5	4.4	7.9	2.5	2.8	1.8	1.0	2.6	2.7	0.2	1.5	2.1	1.7	2.1	2.5
Wears glasses or contact lenses	3.4	3.9	6.0	2.1	2.1	2.2	2.5	2.1	2.2	1.3	1.4	1.3	2.2	2.0	1.7
Breast cancer (self-reported)	3.1	3.7	7.0	-2.0	-2.0	-2.0	-2.2	-1.7	-1.7	-0.2	-1.3	-2.7	-1.9	-2.1	-2.1
Forced expiratory volume in 1-second (FEV1), predicted	2.9	6.1	18.6	-2.2	-1.7	-3.6	-1.7	-2.3	-2.3	-1.1	-1.8	-2.5	-4.3	-2.7	-1.9
Myopia	2.9	4.3	7.7	-2.4	-1.7	-2.2	-2.3	-2.6	-2.8	-0.3	-1.9	-2.0	-0.9	-2.0	-2.3
Qualifications: CSEs or equivalent	2.8	3.7	5.8	-2.2	-1.8	-1.7	-1.7	-2.4	-2.2	-1.5	-1.7	-2.2	-1.3	-2.1	-2.0
Heart attack	2.8	3.6	7.0	1.6	2.6	1.7	0.5	1.6	1.7	2.2	1.5	2.4	2.4	2.0	1.7
Age at last live birth	2.7	3.9	6.9	-1.9	-1.1	-2.6	-0.6	-2.2	-2.4	-1.1	-2.0	-2.6	-1.5	-2.4	-2.1
Fasting Glucose	2.5	3.0	9.2	2.6	2.7	0.8	0.3	1.2	2.0	1.6	0.6	1.0	0.7	1.7	3.0
Townsend deprivation index at recruitment	2.5	3.5	7.7	-2.1	-1.8	-0.8	-1.6	-2.3	-2.1	0.1	-2.0	-1.0	-2.8	-1.9	-2.2
Medication: Cholesterol lowering	2.4	3.8	11.6	1.1	1.6	3.0	-1.4	1.5	1.1	2.4	0.9	1.5	3.4	2.1	1.4
Age started oral contraceptive pill	2.3	2.9	5.7	1.9	2.4	0.9	1.0	1.8	1.8	0.5	1.7	1.9	2.1	1.4	1.8
Time employed in main current job	2.2	2.5	4.4	1.9	1.7	1.6	1.1	2.1	1.8	0.3	1.7	1.1	1.3	1.8	1.8
High cholesterol (Self-reported)	2.2	3.9	9.7	1.5	1.7	3.0	-0.0	1.9	1.6	0.9	1.9	1.6	3.1	2.6	1.8
Medication: Paracetamol	2.2	3.3	8.0	2.0	1.7	1.6	0.6	1.7	2.1	2.0	0.4	2.8	2.1	1.8	1.8
Medication: Atorvastatin	2.2	2.8	5.0	1.5	1.9	2.2	0.6	1.4	1.6	1.8	1.3	2.2	0.9	2.1	1.5
Supplements: Calcium	2.2	2.4	4.1	1.9	0.7	1.2	1.6	1.7	2.0	0.2	1.9	1.9	0.7	1.7	1.9
Migraine (self-reported)	2.1	2.6	4.0	-2.0	-1.6	-1.9	-1.2	-1.9	-1.7	-1.1	-2.0	-0.9	-1.2	-1.6	-1.9
Blood White Count	2.0	15.1	33.5	3.4	3.7	5.8	2.8	3.5	4.0	4.2	2.1	4.6	3.2	4.7	3.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.0	2.3	5.5	1.3	1.7	1.8	0.1	1.4	1.3	1.2	1.5	1.3	1.8	2.3	1.5
Lupus	1.9	2.8	5.6	-1.7	-2.4	-0.9	-2.1	-1.8	-1.8	-0.3	-2.1	-1.9	-0.6	-1.6	-1.6
HbA1C	1.8	2.0	4.8	1.8	1.2	0.4	1.1	0.9	1.4	0.7	1.3	1.9	2.2	1.3	1.9
Diabetes (mother)	1.8	2.3	4.3	-1.8	-1.3	-0.5	-0.6	-2.0	-1.7	-0.7	-2.1	-1.8	-1.0	-1.6	-1.9
Number of incorrect matches in round	1.8	3.0	6.2	1.7	1.7	2.2	1.1	1.8	1.6	1.3	1.5	2.5	1.6	1.8	1.6
Eye problems/disorders: None of the above	1.8	2.1	4.3	-1.6	-1.4	-2.1	-0.6	-1.6	-1.2	-2.0	-1.1	-0.8	-1.5	-1.6	-1.3
Basal cell carcinoma (self-reported)	1.8	2.1	4.8	-1.8	-1.2	-0.8	-0.7	-1.6	-1.7	-1.5	-2.2	-1.1	0.9	-1.3	-1.7
Age when periods started (menarche)	1.7	4.1	10.9	-1.2	-1.9	-3.2	-1.3	-1.3	-1.5	-2.0	-0.6	-2.2	-3.3	-2.4	-1.6
Bilateral oophorectomy (both ovaries removed)	1.7	2.0	3.1	1.5	1.0	1.5	-0.0	1.5	1.7	1.8	0.6	1.7	1.3	1.7	1.6
Medication: Ramipril	1.7	2.1	4.7	1.4	1.0	1.9	-0.4	1.3	1.2	1.4	0.9	1.7	2.2	1.8	1.6
Ever had bowel cancer screening	1.7	2.0	4.1	-1.3	-1.3	-1.8	-1.1	-1.4	-1.5	0.6	-2.0	-1.9	-0.5	-1.4	-1.5
Medication: Gliclazide	1.7	1.9	6.8	1.1	1.2	2.3	0.7	1.1	1.0	2.6	1.2	0.9	0.7	1.5	0.7
Primary Biliary Cirrhosis	1.6	2.3	4.5	-1.7	-2.1	-0.3	-0.1	-1.9	-1.6	2.1	-1.7	-1.3	-0.5	-1.1	-1.9
High blood pressure (mother)	1.6	2.2	4.6	-1.3	-0.5	-2.1	-1.1	-1.3	-1.4	-1.7	-2.0	-1.6	-1.2	-1.7	-1.2
Supplements: Vitamin C	1.6	1.9	2.7	-1.3	-1.5	-1.1	-1.1	-1.5	-1.3	-1.6	-1.6	-1.1	-1.3	-1.5	-1.4
Schizophrenia vs Biploar Disorder	1.5	2.0	9.8	-1.0	-0.9	-1.5	-1.0	-1.0	-1.0	-3.1	-1.1	-1.1	-1.7	-1.2	-0.8
Average weekly spirits intake	1.5	1.9	4.4	1.3	2.1	0.0	0.0	1.9	1.8	0.3	1.0	1.4	1.8	1.0	1.5
Supplements: Zinc	1.5	1.6	3.3	1.8	1.1	0.3	1.6	1.4	1.5	0.2	1.5	1.2	0.3	1.2	1.7
Standing height	1.5	14.7	30.1	-3.8	-3.1	-4.4	-2.5	-3.8	-3.9	-2.6	-2.9	-4.6	-5.5	-4.4	-3.4
Guilty feelings	1.5	2.3	3.3	-1.8	-1.3	-1.7	-1.8	-1.7	-1.8	-0.7	-1.0	-1.4	-1.6	-1.4	-1.6
Height	1.4	26.7	39.0	-5.0	-4.4	-6.1	-3.6	-5.3	-5.5	-4.4	-3.9	-6.1	-6.2	-6.0	-4.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.4	3.1	4.9	-1.9	-2.0	-1.2	-1.8	-1.9	-2.0	1.3	-2.2	-1.9	-1.3	-1.3	-1.8
Bipolar Disorder (2018)	1.3	2.1	3.0	1.6	1.3	1.2	1.7	1.5	1.6	1.6	1.1	1.7	1.2	1.3	1.6
Leg fat-free mass (left)	1.3	6.8	10.8	-3.1	-2.4	-1.3	-1.3	-3.1	-2.9	-1.9	-2.6	-3.0	-3.3	-2.8	-2.9
Leg predicted mass (left)	1.3	6.8	10.3	-3.1	-2.4	-1.2	-1.3	-3.1	-2.9	-1.8	-2.6	-3.0	-3.2	-2.8	-2.9
Exposure to tobacco smoke at home	1.3	1.5	2.7	1.1	0.9	1.6	1.1	1.0	1.1	1.6	1.2	1.3	1.2	1.3	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	1.9	3.0	-1.7	-1.5	-0.9	-1.5	-1.5	-1.6	-0.3	-1.7	-1.3	-1.5	-1.2	-1.3
Medication: Amlodipine	1.3	1.9	3.2	-1.1	-1.2	-1.2	-1.6	-1.4	-1.5	-1.8	-1.1	-1.2	-1.4	-1.6	-1.3
Number of full brothers	1.3	1.6	2.9	1.3	1.4	1.7	1.3	1.2	1.4	-0.1	1.1	1.4	1.4	1.1	1.1
Osteoarthritis (self-reported)	1.3	1.7	4.4	1.0	0.8	2.0	0.5	1.2	1.2	-0.3	1.3	1.2	2.1	1.5	1.2
Angina	1.2	1.5	3.2	0.7	1.5	1.8	-0.1	1.0	0.9	1.5	0.9	1.5	1.3	1.6	1.0
Medication: Co-codamol	1.2	1.4	3.8	1.3	0.5	1.1	1.2	0.8	1.2	1.2	0.8	1.7	1.9	1.0	1.0
Trunk fat-free mass	1.2	6.7	13.3	-3.0	-2.7	-1.4	-0.3	-2.9	-2.7	-1.2	-2.3	-3.2	-3.6	-2.9	-2.7
Hip circumference	1.2	5.0	7.9	-2.8	-2.1	-1.0	-1.5	-2.7	-2.6	-2.2	-2.7	-2.1	-0.6	-2.5	-2.7
Trunk predicted mass	1.2	6.7	13.2	-3.0	-2.7	-1.4	-0.2	-2.9	-2.7	-1.2	-2.3	-3.2	-3.6	-2.8	-2.7
Emphysema/chronic bronchitis	1.2	1.4	5.3	0.8	1.7	1.4	0.0	0.4	0.7	2.3	0.6	1.0	-0.9	1.7	0.8
Overall health rating	1.2	2.6	4.7	-1.6	-0.9	-2.0	-2.2	-1.5	-1.3	-1.9	-1.2	-1.1	-2.0	-1.6	-1.3
Family relationship satisfaction	1.2	1.4	4.5	-1.1	0.3	-0.8	-0.8	-0.8	-0.7	-2.1	-1.7	0.2	-1.7	-1.4	-1.0
Whole body fat-free mass	1.2	7.0	13.8	-3.1	-2.6	-1.4	-0.7	-3.0	-2.8	-1.5	-2.4	-3.2	-3.7	-2.9	-2.8
Basal metabolic rate	1.2	6.8	10.8	-3.1	-2.5	-1.3	-0.9	-3.0	-2.9	-1.7	-2.5	-3.0	-3.3	-2.9	-2.9
Number of operations (self-reported)	1.2	1.8	4.9	1.7	0.9	0.2	0.5	1.8	1.7	0.9	0.9	2.2	0.6	1.2	1.6
Irritability	1.2	2.0	7.4	0.4	1.2	2.2	0.7	0.7	0.5	2.7	1.2	0.6	2.2	1.6	0.6
Alcohol drinker status: Previous	1.2	1.4	4.0	-1.3	-0.5	-1.4	-0.6	-1.2	-1.0	-1.2	-1.3	-0.2	-2.0	-1.2	-1.1
Pack years of smoking	1.2	1.8	4.7	-1.4	-0.6	-0.5	-2.2	-1.0	-1.2	-1.9	-1.3	-1.8	-0.9	-1.2	-1.3
Depression (Nagel 2018)	1.1	1.7	3.4	1.2	1.0	0.8	1.3	1.4	1.4	0.1	1.2	1.9	1.2	1.6	1.5
Hearing difficulty/problems: Yes	1.1	1.7	6.4	-1.4	-0.7	-0.5	-2.5	-1.6	-1.7	0.7	-0.9	-1.7	-0.7	-0.6	-1.1
Current tobacco smoking	1.1	1.8	4.6	1.3	0.9	1.0	-0.7	1.6	1.7	0.5	1.0	2.1	0.5	1.8	1.5
Hearing difficulty/problems with background noise	1.1	1.7	6.7	-1.5	-1.0	-0.6	-2.6	-1.3	-1.5	-0.4	-0.7	-1.9	-0.9	-0.7	-1.1
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	3.8	1.2	1.8	0.2	1.9	1.1	1.4	-0.6	1.0	1.4	0.3	0.7	1.0
Pulse rate	1.1	1.8	3.9	1.7	2.0	1.0	-0.3	1.8	1.5	1.7	0.8	0.9	0.3	1.3	1.4
Medication: Ventolin 100micrograms inhaler	1.1	1.4	6.2	1.1	1.4	-0.0	0.5	0.8	1.0	2.5	1.2	1.0	0.1	1.3	1.2
Leg fat-free mass (right)	1.1	6.1	11.5	-2.9	-2.3	-1.2	-1.3	-2.9	-2.7	-1.5	-2.2	-2.9	-3.4	-2.6	-2.7
Asthma (self-reported)	1.1	2.1	4.1	1.7	2.0	0.6	0.0	1.8	1.8	-0.3	1.4	1.7	1.1	1.6	1.7
Whole body water mass	1.1	6.4	13.1	-3.0	-2.5	-1.3	-0.7	-2.9	-2.7	-1.4	-2.3	-3.0	-3.6	-2.7	-2.7
Leg predicted mass (right)	1.1	6.0	11.5	-2.9	-2.3	-1.2	-1.3	-2.9	-2.7	-1.5	-2.2	-2.8	-3.4	-2.6	-2.6
Number of treatments/medications taken	1.0	1.8	3.4	1.3	1.6	1.2	-0.6	1.3	1.3	1.6	0.2	1.7	1.9	1.4	1.3
Sitting height	1.0	7.0	19.7	-2.8	-1.9	-2.5	-2.3	-2.8	-2.8	-1.4	-2.1	-2.8	-4.4	-2.7	-2.2
Financial difficulties in last 2 years	1.0	1.3	9.1	-0.8	0.3	-1.4	-1.4	-0.7	-0.6	-0.5	-0.8	-0.2	-3.0	-0.7	-0.6
Medication: Simvastatin	1.0	1.5	5.4	0.5	0.5	2.0	-1.4	0.7	0.5	0.9	0.9	0.4	2.3	1.7	0.8
Prospective memory result	1.0	1.2	2.5	1.2	0.9	1.6	0.6	1.3	1.2	0.9	1.1	1.0	0.6	1.2	1.0
Medication for cholesterol, blood pressure or diabetes	1.0	1.6	9.2	-0.3	-0.4	-1.7	2.3	-0.5	-0.1	-0.7	0.3	-0.3	-3.0	-0.9	-0.6
Medication: Seretide 50 evohaler	1.0	1.2	2.4	-1.2	-0.5	-0.0	-1.4	-1.2	-1.3	0.7	-1.3	-1.5	-0.8	-0.5	-1.2
Arm predicted mass (right)	1.0	5.1	10.2	-2.7	-2.2	-1.1	-0.8	-2.6	-2.4	-1.4	-2.0	-2.7	-3.2	-2.5	-2.5
Alcohol intake frequency.	1.0	2.4	9.2	-1.7	-0.9	-1.4	0.5	-1.9	-0.9	-0.7	-2.0	-0.5	-3.0	-1.6	-1.6
Medication: Aspirin	1.0	1.3	5.3	0.8	1.2	1.2	-0.9	0.5	0.4	2.3	0.3	1.0	1.5	1.2	0.7
Pain type(s) experienced in last month: Hip pain	1.0	1.2	5.9	0.6	0.5	2.4	-0.3	0.8	0.8	1.0	0.6	0.9	0.9	1.8	0.9
Arm fat-free mass (left)	1.0	5.2	8.4	-2.8	-2.1	-1.2	-0.7	-2.6	-2.5	-1.8	-1.9	-2.6	-2.9	-2.5	-2.5
Medication for hormone replacement therapy	0.9	1.0	3.4	1.0	1.3	1.9	-0.3	0.9	0.9	1.0	0.4	0.7	-0.6	1.3	1.0
Hand grip strength (right)	0.9	2.5	4.8	-2.2	-1.4	-0.4	-0.6	-2.2	-2.2	0.8	-1.6	-1.8	-0.8	-1.2	-2.0
Relative age voice broke	0.9	1.4	3.4	1.1	1.1	0.5	1.7	1.1	1.4	0.3	1.8	1.1	-0.4	1.1	1.2
Asthma	0.9	1.9	3.3	1.6	1.8	0.4	-0.4	1.6	1.7	-0.3	1.3	1.7	1.1	1.5	1.6
Lung cancer (father)	0.9	1.1	9.2	-0.8	-1.0	0.2	-3.0	-0.5	-0.8	-0.7	0.3	-0.8	-0.4	0.1	-0.4
Blood clot in the leg (DVT)	0.9	1.2	2.3	-1.4	-0.9	0.5	0.1	-1.5	-1.0	0.9	-1.4	-1.1	-1.2	-0.7	-1.4
Arm fat-free mass (right)	0.9	4.8	8.7	-2.6	-2.2	-1.1	-0.8	-2.5	-2.3	-1.2	-2.0	-2.7	-2.9	-2.5	-2.4
Worry too long after embarrassment	0.9	1.4	2.7	-1.2	-1.0	-1.6	-1.6	-1.0	-1.3	-0.7	-1.3	-1.1	-0.7	-1.3	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.1	5.0	-0.8	-2.2	-0.4	-0.5	-0.7	-1.0	-0.2	-1.0	-1.4	-0.4	-1.2	-1.0
Angina (self-reported)	0.9	1.2	3.1	0.5	1.3	1.5	-0.1	0.8	0.8	1.8	0.6	1.2	1.0	1.3	0.9
Suffer from ‘nerves’	0.9	1.3	2.9	-1.4	-1.1	-0.5	-0.2	-1.5	-1.5	-0.6	-1.7	-1.0	-0.2	-1.2	-1.5
Eye problems/disorders: Cataract	0.9	1.0	7.1	1.0	1.1	0.4	0.2	0.7	0.7	2.7	0.4	0.5	-0.1	0.6	0.7
Type 2 Diabetes (T2D) (2012)	0.8	0.9	2.6	0.9	0.9	1.2	1.4	0.7	0.9	0.6	0.4	1.6	0.7	0.9	0.5
Frequency of depressed mood in last 2 weeks	0.8	1.1	2.3	0.9	0.9	0.7	0.6	1.1	1.1	0.5	1.0	1.5	1.2	1.3	1.1
Ever used hormone-replacement therapy (HRT)	0.8	1.1	2.3	0.8	1.4	1.5	-0.6	0.8	1.0	0.8	0.5	1.2	0.7	1.4	0.9
Stomach or abdominal pain in last month	0.8	1.1	8.7	-0.3	0.8	-0.9	-0.3	-0.5	-0.3	-0.9	-0.5	-0.8	-2.9	-0.6	-0.3
Qualifications: None of the above	0.8	1.7	4.0	1.8	1.0	1.1	0.0	1.8	1.5	0.6	2.0	1.4	0.5	1.1	1.6
Pain all over the body in last month	0.8	0.9	1.9	-0.8	-0.9	-0.3	-0.4	-1.3	-1.2	0.5	-1.4	-1.2	-0.9	-0.7	-0.9
Weight	0.8	4.1	6.8	-2.6	-1.8	-0.6	-0.9	-2.5	-2.3	-1.6	-2.4	-2.2	-1.5	-2.3	-2.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.5	5.4	-1.9	-2.0	0.1	-0.9	-1.8	-2.1	0.8	-2.3	-1.7	-0.8	-0.9	-1.8
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	2.9	-1.4	-1.0	-0.7	-1.7	-1.3	-1.3	0.3	-1.1	-0.8	-1.0	-0.7	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	3.3	-0.7	-0.4	-0.7	-1.8	-0.7	-0.9	-1.6	-1.2	-0.4	0.2	-0.5	-0.3
Smoking status: Current	0.8	1.2	4.1	1.1	0.7	0.7	-0.6	1.4	1.5	0.3	0.5	2.0	0.4	1.5	1.2
Average weekly champagne plus white wine intake	0.8	1.1	2.1	1.2	1.1	1.3	1.4	1.0	0.9	1.3	0.3	1.1	0.8	0.9	0.8
Tinnitus: Yes, now most or all of the time	0.8	0.9	1.7	1.2	0.5	1.0	0.6	1.3	1.2	-0.4	1.0	0.8	1.2	0.9	1.1
Eye problems/disorders: Glaucoma	0.8	0.9	2.9	0.9	1.0	1.7	1.0	0.9	0.6	0.5	0.4	0.7	1.5	0.7	0.8
Arm predicted mass (left)	0.8	4.2	7.6	-2.5	-1.9	-0.9	-0.4	-2.3	-2.1	-1.6	-1.7	-2.4	-2.8	-2.3	-2.3
Intelligence (Savage-Jansen 2018)	0.7	2.2	5.3	-1.5	-1.1	-2.3	-0.4	-1.6	-1.5	0.7	-1.5	-1.3	-1.6	-1.9	-1.5
Mean Putamen Volume	0.7	0.8	2.0	-0.9	-1.4	-0.1	-1.1	-0.6	-0.9	1.3	-0.5	-0.8	0.6	-0.6	-0.9
HDL Cholesterol	0.7	1.2	2.4	-1.1	-0.6	-1.3	-0.5	-1.5	-1.2	0.0	-1.1	-1.4	-1.4	-1.1	-1.0
Hand grip strength (left)	0.7	2.0	3.8	-1.8	-1.1	-0.4	0.9	-1.9	-1.8	1.4	-1.6	-1.3	-0.2	-1.2	-1.8
Hair/balding pattern: Pattern 2	0.7	0.9	7.8	-0.5	-1.0	0.3	-2.8	-0.5	-0.4	0.0	0.7	-0.6	-0.1	0.5	-0.2
Happiness	0.7	0.9	1.9	-1.2	-0.5	-1.4	-1.0	-0.9	-1.0	-0.2	-1.0	-0.2	-0.8	-1.1	-1.0
Qualifications: A levels/AS levels or equivalent	0.7	1.6	3.8	-1.9	-0.9	-0.3	0.2	-1.7	-1.6	1.3	-1.6	-1.0	-0.3	-0.9	-1.8
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	3.7	0.8	0.4	1.2	0.6	0.2	0.4	1.9	0.8	0.9	-0.2	1.0	0.7
Medication: Lansoprazole	0.7	0.8	2.9	-0.7	-0.8	-1.2	0.4	-0.6	-0.5	-1.0	-0.8	-0.4	-1.7	-0.9	-0.7
Length of working week for main job	0.7	0.8	1.6	0.9	0.2	1.0	1.3	0.6	0.8	0.9	0.8	1.2	0.8	0.8	0.8
Pulse wave reflection index	0.7	0.8	1.4	-1.1	-0.7	-0.3	-0.0	-1.2	-1.1	0.2	-1.1	-1.1	-1.2	-0.9	-1.0
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.4	-1.1	-0.6	-1.2	-0.1	-0.8	-1.1	-0.9	-0.7	-0.6	-0.0	-1.6	-1.1
Birth weight	0.7	1.5	3.1	-1.1	-1.7	-1.8	-1.3	-0.8	-0.9	-1.4	-0.8	-1.3	-0.1	-1.5	-1.0
Comparative body size at age 10	0.7	1.9	8.1	0.7	-0.4	1.6	2.9	0.3	0.8	2.6	0.1	0.8	1.4	0.8	0.5
Pulse rate, automated reading	0.7	2.4	5.1	2.0	2.3	1.0	1.0	1.7	2.0	1.2	0.4	2.1	0.4	1.5	1.5
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	1.8	-0.9	-1.3	-0.5	-0.2	-1.1	-1.2	-1.1	-0.5	-1.0	0.8	-0.8	-1.1
Medication for cholesterol	0.7	1.1	2.6	-1.2	-1.6	-0.2	-0.3	-1.1	-1.4	0.4	-0.8	-1.4	0.2	-1.1	-1.3
Mineral and other dietary supplements	0.7	1.0	2.1	-1.4	-1.1	0.0	-0.3	-1.0	-1.4	-0.6	-0.8	-1.2	-0.0	-1.0	-1.5
Medication: Aspirin	0.7	1.0	4.8	0.4	1.0	0.9	-0.9	0.1	0.1	2.2	0.0	0.9	1.4	1.0	0.4
Number of self-reported non-cancer illnesses	0.7	1.1	2.7	1.1	1.2	0.7	-0.0	1.1	1.2	0.4	0.8	1.7	1.1	1.3	1.2
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.6	-1.1	-0.6	0.7	0.4	-1.2	-0.7	1.2	-1.0	-0.9	-1.3	-0.6	-1.1
Verbal and Numeric Reasoning (VNR)	0.6	1.5	5.8	-0.9	-0.9	-2.4	-0.4	-1.2	-0.8	-0.3	-1.4	-0.3	-1.9	-1.5	-0.9
Lung FVC	0.6	3.0	13.5	1.0	0.1	3.1	0.6	1.1	1.1	3.7	-0.5	0.7	1.3	2.3	1.0
Pack years adult smoking proportion	0.6	0.9	2.7	-0.9	-0.1	-0.2	-1.6	-0.5	-0.7	-1.6	-0.9	-1.2	-1.0	-0.6	-0.8
Alcohol usually taken with meals	0.6	1.0	5.0	0.8	1.1	1.3	2.2	0.6	0.8	1.4	0.3	0.5	0.3	0.6	0.3
Mouth/teeth dental problems	0.6	1.0	2.6	0.5	0.3	1.6	0.1	0.1	0.3	1.4	1.0	1.0	1.4	1.5	0.6
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	4.1	-1.7	-2.0	0.3	-0.5	-1.7	-1.8	0.8	-2.0	-1.3	-0.7	-0.8	-1.5
Mouth/teeth dental problems: Dentures	0.6	1.1	2.6	1.3	1.2	0.5	0.7	1.6	1.6	-0.5	0.7	0.6	0.9	0.8	1.3
Medication: Paracetamol	0.6	1.0	3.6	1.0	0.5	0.9	0.1	0.7	1.0	1.9	-0.5	1.6	0.7	0.8	0.8
Wheeze or whistling in the chest in last year	0.6	1.1	3.1	0.6	1.8	1.4	-0.9	0.7	0.8	1.6	0.2	0.7	0.6	1.5	0.8
Age at first live birth	0.6	1.0	3.1	-0.8	-0.6	-1.8	-0.9	-1.0	-1.1	0.2	-0.7	-1.4	-0.5	-1.0	-0.8
Medication: Blood pressure	0.6	1.0	6.3	-0.0	-0.2	0.9	-2.5	-0.2	-0.5	-0.1	-0.4	-0.7	2.0	0.3	0.1
Number of full sisters	0.6	0.7	1.7	1.0	-0.0	0.4	1.0	1.0	1.2	-0.5	0.8	1.3	-0.1	0.8	1.0
Chest pain or discomfort	0.6	0.9	3.9	0.3	2.0	-0.2	-1.8	0.4	0.4	1.3	-0.1	0.2	-0.7	0.8	0.7
Long-standing illness, disability or infirmity	0.6	0.9	3.8	-1.1	-0.8	-0.4	-2.0	-1.0	-1.1	-0.2	-1.1	-0.5	-0.4	-0.5	-1.0
Hearing aid user	0.6	0.7	2.9	0.2	0.6	0.4	-1.7	0.5	0.4	0.8	0.2	0.4	1.4	1.0	0.7
Commuting to job workplace: Public transport	0.6	0.7	4.0	0.4	-0.2	-0.2	-1.9	0.1	-0.0	0.0	0.1	0.4	-2.0	0.4	0.6
Ever had prostate specific antigen (PSA) test	0.6	0.7	6.1	-0.0	0.2	-0.3	-2.5	0.2	-0.4	0.5	0.1	-0.6	1.0	-0.0	0.3
Bipolar Disorder or Schizophrenia	0.5	1.2	2.4	1.3	1.4	0.7	1.5	1.1	1.2	0.4	0.5	0.9	1.1	1.1	1.3
Age at First Birth	0.5	0.7	3.3	0.8	0.7	0.1	-1.0	0.5	0.3	1.8	0.7	0.1	0.2	1.0	0.9
Coronary Artery Disease (CAD)	0.5	0.6	5.0	0.4	-0.2	0.7	-0.1	0.2	0.1	2.2	0.3	0.7	-0.2	0.9	0.5
Rheumatoid Arthritis	0.5	0.6	1.9	1.2	0.2	0.1	0.2	1.2	1.4	0.0	0.5	1.1	0.5	0.5	1.0
Ever had hysterectomy (womb removed)	0.5	0.5	2.8	0.6	0.2	-0.0	0.8	0.6	0.9	-1.7	-0.4	0.8	0.1	0.2	0.6
Diabetes (father)	0.5	0.6	1.5	-0.7	-0.7	-0.7	1.1	-0.8	-0.4	1.1	-0.2	-0.0	-1.2	-0.3	-0.8
Trunk fat mass	0.5	2.3	4.1	-2.0	-1.0	-0.3	-0.8	-1.9	-1.8	-1.5	-1.8	-1.4	0.4	-1.8	-2.0
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	1.8	-0.8	-0.7	-1.1	-1.3	-1.0	-0.9	-0.5	-0.6	-0.8	-0.9	-0.7	-0.7
Arm fat mass (right)	0.5	2.2	4.0	-1.9	-1.2	0.1	-0.3	-1.8	-1.7	-1.5	-2.0	-1.3	0.3	-1.6	-2.0
Hair/balding pattern: Pattern 4	0.5	1.2	3.2	1.4	1.2	-0.1	1.8	1.1	1.4	-1.3	0.8	1.0	0.8	0.5	1.0
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.5	-1.2	-0.6	-0.4	0.4	-0.9	-1.0	0.0	-0.5	-0.5	0.2	-1.0	-1.2
Forced vital capacity (FVC), Best measure	0.5	1.9	4.1	-1.5	-1.6	0.1	-1.2	-1.4	-1.6	1.4	-2.0	-1.4	-1.2	-0.5	-1.3
Health satisfaction	0.5	0.6	3.0	-0.8	-0.7	-0.5	-1.7	-0.6	-0.5	-0.6	-1.1	0.1	0.1	-0.5	-0.5
Shortness of breath walking on level ground	0.5	0.5	1.8	-0.8	-0.7	-0.1	-0.7	-0.8	-0.8	0.2	-1.4	-0.8	-0.5	-0.7	-0.6
Medication for pain relief, constipation, heartburn	0.5	0.8	3.8	-0.5	-0.5	-1.0	0.0	-0.4	-0.5	-1.9	0.9	-1.5	-0.8	-0.6	-0.3
Neck or shoulder pain in last month	0.5	0.7	4.9	-0.3	-0.0	-0.2	-1.2	-0.2	-0.2	-2.2	-1.0	-0.1	-0.4	-0.2	-0.4
Medication: Ibuprofen	0.5	0.6	1.5	-0.7	-0.3	-1.2	-0.0	-0.9	-0.7	0.0	-1.0	-0.1	-0.9	-1.1	-0.9
Whole body fat mass	0.5	2.0	3.6	-1.9	-1.0	-0.2	-0.6	-1.8	-1.6	-1.5	-1.8	-1.2	0.5	-1.7	-1.9
Leg fat mass (right)	0.5	1.9	3.8	-1.9	-0.9	0.3	-0.2	-1.7	-1.5	-1.4	-1.9	-0.8	0.9	-1.5	-1.9
Qualifications: nursing, teaching	0.5	0.8	3.2	0.6	1.1	0.7	1.8	0.5	0.7	1.3	0.2	0.8	0.7	0.7	0.6
Back pain experienced in last month	0.5	0.7	1.6	0.9	1.3	0.9	-0.6	1.0	1.0	0.8	-0.4	0.6	0.9	0.7	0.5
Alcohol drinker status: Never	0.5	0.5	3.8	0.5	-0.2	0.4	1.9	0.4	0.7	0.6	-0.4	0.3	1.0	0.2	0.3
Ovarian Cancer	0.4	0.5	3.0	0.5	-0.2	-0.3	0.9	0.5	0.5	-1.1	0.5	0.3	-1.7	-0.1	0.4
Blood Red Count	0.4	4.1	12.7	-2.5	-1.4	-1.8	-3.6	-2.2	-2.4	-0.6	-2.4	-1.0	0.3	-2.0	-1.9
Allergy or Eczema	0.4	1.0	4.3	-0.3	-0.0	-0.2	0.6	-0.5	-0.4	-2.1	-1.2	-0.2	1.8	-1.2	-0.9
Chronotype (morning person)	0.4	0.9	2.4	0.8	0.6	0.9	1.4	0.8	1.1	1.0	0.7	0.7	-1.6	0.6	0.6
Sensitivity / hurt feelings	0.4	0.6	1.3	0.7	1.1	0.1	-0.2	0.8	0.8	-0.8	1.0	1.1	0.7	0.5	0.8
Systolic blood pressure, automated reading	0.4	1.1	2.0	1.1	1.4	0.7	0.2	1.3	1.1	-0.6	1.1	0.8	1.2	1.2	1.1
Vitamin and mineral supplements	0.4	0.5	2.2	-0.3	0.7	1.0	-0.3	-0.1	-0.4	1.2	0.4	-0.3	1.5	0.7	0.0
Severe depression (siblings)	0.4	0.4	1.1	-0.7	-0.5	-0.4	1.1	-0.6	-0.3	0.0	-0.7	0.3	-0.7	-0.9	-1.0
Trunk fat percentage	0.4	1.5	2.7	-1.4	-0.5	-0.2	-0.9	-1.4	-1.4	-1.6	-1.4	-0.8	1.4	-1.4	-1.5
Average weekly fortified wine intake	0.4	0.5	1.4	-0.9	-0.6	1.2	-0.4	-0.8	-0.8	0.8	0.0	-0.8	-0.1	0.1	-0.8
Hayfever, allergic rhinitis or eczema	0.4	0.9	3.0	-0.6	-0.4	0.1	0.9	-0.7	-0.6	-1.6	-1.1	-0.6	1.7	-1.0	-0.9
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	3.4	-0.2	0.4	-0.8	-0.3	0.0	-0.0	-1.9	-0.9	-0.1	-0.3	-0.7	-0.1
Fluid intelligence score	0.4	0.7	3.8	-0.3	-0.4	-2.0	0.0	-0.7	-0.4	-0.2	-0.4	-0.2	-1.8	-0.8	-0.2
Worrier / anxious feelings	0.4	0.7	3.1	0.6	1.8	0.6	0.1	0.6	0.6	0.7	1.2	0.3	0.4	1.0	0.8
Falls in the last year	0.4	0.5	2.7	-0.6	-0.6	-0.3	0.0	-0.5	-0.3	-1.6	-0.4	0.3	-1.3	-0.6	-0.6
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.6	1.8	-0.6	-0.3	-1.1	0.2	-0.7	-0.5	0.1	-1.1	0.1	-1.3	-0.9	-0.8
Peak expiratory flow (PEF)	0.4	1.0	3.2	-1.3	-1.8	0.7	-0.3	-1.0	-1.1	0.8	-0.8	-0.6	0.9	-0.3	-1.2
Gout (self-reported)	0.4	0.5	1.5	-0.0	0.2	-0.7	-1.1	0.4	0.5	-1.2	-0.1	1.1	-1.0	-0.5	0.3
Leg fat percentage (right)	0.4	1.3	7.5	-1.0	-0.1	1.2	0.8	-0.8	-0.6	-0.8	-1.1	0.2	2.7	-0.7	-1.2
Heart disease (mother)	0.4	0.4	1.3	0.6	0.6	0.8	-0.8	0.7	0.4	0.1	0.7	0.1	1.1	0.6	0.6
Commuting to job workplace: Car/motor vehicle	0.4	0.4	2.5	-0.4	-0.9	-0.1	-0.2	-0.2	-0.3	-0.7	-0.5	-0.6	1.6	-0.3	-0.4
Loneliness, isolation	0.4	0.6	2.1	-0.5	-0.6	-1.3	-0.4	-0.5	-0.3	-1.5	-0.5	0.4	-1.3	-0.6	-0.2
Illnesses of father: None of the above (group 1)	0.4	0.5	1.2	-0.6	-0.2	-0.4	-0.6	-0.8	-0.9	-0.4	-0.8	-1.1	-1.1	-0.7	-0.5
Arm fat mass (left)	0.4	1.8	3.4	-1.8	-1.0	0.3	-0.3	-1.7	-1.6	-1.2	-1.8	-1.3	0.4	-1.4	-1.8
Miserableness	0.4	0.7	2.4	-0.6	-0.5	-1.6	-1.2	-0.6	-0.6	-0.6	-0.1	-0.6	-0.8	-1.0	-0.6
Medication: Blood pressure	0.4	0.7	1.8	1.0	1.3	-0.2	0.5	0.8	1.1	0.9	0.4	1.1	0.1	0.6	1.0
Medication: Bendroflumethiazide	0.4	0.6	3.1	-0.2	-0.5	-1.4	-1.8	-0.5	-0.4	-0.0	0.3	-1.0	0.0	-0.5	-0.0
Medication: Lisinopril	0.4	0.5	1.3	0.7	0.3	1.1	0.1	0.6	0.7	1.1	0.2	0.5	0.4	1.0	0.8
Ever smoked	0.4	0.7	1.6	0.8	1.1	0.1	0.6	1.1	1.2	-0.7	0.5	1.3	-0.6	0.4	0.7
Diastolic blood pressure, automated reading	0.4	1.1	2.2	1.1	1.2	0.9	0.7	1.1	1.1	-0.6	0.6	1.5	0.6	1.3	1.2
Heart disease (siblings)	0.4	0.5	2.4	0.5	0.0	0.6	0.3	0.4	0.5	1.0	1.1	0.5	1.5	0.5	0.4
Leg fat mass (left)	0.4	1.4	2.8	-1.6	-0.8	0.5	-0.3	-1.5	-1.3	-1.3	-1.5	-0.6	1.3	-1.2	-1.7
Alzheimer’s Disease (in mother)	0.3	0.3	2.0	0.5	-0.5	-0.4	0.3	0.2	0.5	-1.4	0.0	0.8	-0.2	0.1	0.1
Alzheimer’s Disease (including proxy)	0.3	0.5	1.7	-0.2	-1.3	-0.6	-1.0	-0.7	-0.5	-1.2	-0.3	-0.3	-0.3	-0.5	-0.3
Crohns Disease (2017)	0.3	0.6	1.7	-1.2	-0.9	0.3	0.1	-1.0	-0.7	-0.1	-1.3	-0.4	-0.7	-0.6	-0.9
Body Mass Index (BMI) (2010)	0.3	0.4	0.9	0.8	0.2	0.4	1.0	0.7	0.7	0.3	1.0	0.1	0.0	0.8	0.9
Triglycerides	0.3	0.5	2.0	-0.4	-0.6	-1.4	1.0	-0.5	-0.2	0.4	-0.3	0.2	-1.1	-0.9	-0.4
Ulcerative Colitis	0.3	0.5	3.5	0.0	-0.6	0.6	0.1	-0.1	0.3	1.9	-0.3	0.6	1.0	0.5	0.0
Smoking Status	0.3	0.7	4.5	0.5	0.1	0.4	0.0	0.9	1.1	-1.2	-0.2	2.1	0.1	0.4	0.5
Respiratory disease	0.3	0.7	3.7	0.9	1.9	0.4	0.4	0.9	1.0	0.1	0.2	0.8	0.2	0.9	0.7
Relative age of first facial hair	0.3	0.7	2.9	-0.6	-1.1	-1.3	-0.1	-0.6	-0.5	-1.7	0.0	-0.6	-0.6	-0.8	-0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	3.1	0.4	-0.2	1.8	0.4	0.6	0.3	-0.0	0.5	0.2	0.4	0.5	0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.5	-0.2	-0.2	-0.6	-1.0	-0.1	-0.1	0.1	-0.2	1.2	-0.9	-0.0	0.1
Serious illness, injury or assault to yourself	0.3	0.3	1.3	-0.6	-0.4	-0.4	-1.1	-0.4	-0.4	0.3	-0.3	-0.2	-0.8	-0.5	-0.4
Medication: Atenolol	0.3	0.4	3.3	-0.2	-0.1	-0.3	-1.8	-0.1	-0.3	0.4	-0.2	-1.0	-0.2	-0.2	0.2
Medication: Levothyroxine sodium	0.3	0.5	1.5	1.2	0.9	0.1	0.2	1.1	0.7	0.5	1.1	0.0	0.3	0.4	0.8
Waist circumference	0.3	1.1	2.2	-1.3	-0.6	0.2	-0.4	-1.1	-0.9	-1.5	-1.5	-0.7	0.9	-1.1	-1.3
Past tobacco smoking	0.3	0.5	1.6	-0.7	-0.6	0.0	-0.7	-0.8	-0.8	1.2	-0.1	-1.2	0.8	0.0	-0.5
Had other major operations	0.3	0.4	1.0	-0.0	-1.0	-0.7	0.8	-0.1	0.1	-0.5	-0.5	-0.2	-1.0	-0.8	-0.3
Forced vital capacity (FVC)	0.3	1.3	3.0	-1.2	-1.6	0.4	-0.3	-1.3	-1.3	1.1	-1.7	-1.1	-1.1	-0.4	-1.1
Diabetes (self-reported)	0.3	0.4	1.4	0.5	-0.3	1.2	-0.1	0.5	0.5	0.3	0.8	0.8	0.7	0.6	0.5
Arm fat percentage (right)	0.3	1.3	3.9	-1.3	-0.5	0.8	0.3	-1.2	-1.1	-1.0	-1.4	-0.4	2.0	-0.8	-1.5
Illnesses of mother	0.3	0.4	1.0	0.5	0.4	0.5	0.7	0.8	0.6	0.2	0.9	1.0	0.7	0.5	0.6
Pulse wave Arterial Stiffness index	0.3	0.3	0.7	-0.4	0.1	-0.7	-0.8	-0.5	-0.5	-0.1	-0.8	-0.8	-0.5	-0.6	-0.3
Tense / ‘highly strung’	0.3	0.4	2.8	-0.3	0.9	0.6	-1.7	0.1	-0.2	-0.5	0.3	-0.2	0.3	0.8	0.0
High blood pressure (siblings)	0.3	0.5	3.1	-0.1	0.5	-0.2	0.1	0.0	0.0	1.8	0.9	-0.7	-0.8	0.3	-0.0
Body fat percentage	0.3	1.2	4.2	-1.2	-0.3	0.4	-0.3	-1.1	-1.0	-1.2	-1.3	-0.4	2.1	-1.0	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.2	0.6	0.6	0.3	0.5	0.6	0.4	0.4	0.3	1.1	0.8	0.6	0.5
Mouth/teeth dental problems: Loose teeth	0.3	0.3	2.2	-0.3	-0.3	-0.3	-0.2	-0.1	-0.3	-0.8	-0.2	-0.6	-1.5	-0.5	-0.3
Medication: Allopurinol	0.3	0.3	1.5	-0.2	0.3	-0.4	-1.2	0.4	0.3	-1.2	-0.3	0.7	-0.2	-0.3	0.2
Mean time to correctly identify matches	0.3	0.5	3.8	0.8	0.2	0.5	-0.4	0.8	0.7	-2.0	0.0	-0.0	0.2	0.2	0.5
Had major operations	0.3	0.4	1.3	0.5	0.8	-1.1	0.6	0.5	0.4	0.3	0.6	0.9	0.6	0.0	0.4
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	3.4	0.2	0.1	0.0	0.6	0.2	-0.1	-0.7	-0.0	-0.4	1.8	-0.1	0.1
Knee pain experienced in last month	0.3	0.4	3.3	-0.3	0.3	0.3	-0.9	-0.2	0.0	-0.6	-0.0	-0.1	-1.8	-0.1	-0.1
Arm fat percentage (left)	0.3	1.1	3.7	-1.1	-0.4	1.1	0.3	-1.1	-0.9	-0.7	-1.3	-0.4	1.9	-0.6	-1.3
Friendships satisfaction	0.3	0.4	1.4	0.2	1.2	0.8	-0.2	0.3	0.5	0.7	0.2	0.9	-0.0	0.8	0.5
Osteoporosis (self-reported)	0.3	0.4	1.5	-0.2	-0.2	-0.0	-1.2	-0.6	-0.4	0.5	-0.7	-0.8	-0.9	0.1	-0.2
Leg fat percentage (left)	0.3	1.2	9.0	-0.8	-0.0	1.3	0.6	-0.6	-0.5	-0.6	-0.7	0.3	3.0	-0.4	-1.0
Average weekly beer plus cider intake	0.3	0.4	1.0	-0.7	-1.0	0.5	-0.6	-0.6	-0.6	-0.8	0.4	-0.4	-0.7	-0.2	-0.6
Risk taking	0.3	0.4	1.9	0.5	0.3	-0.6	-0.3	0.4	0.5	-0.0	-0.1	1.4	-1.1	0.3	0.4
Fractured/broken bones in last 5 years	0.3	0.4	1.2	0.1	1.0	0.6	1.1	0.2	0.2	0.5	1.0	0.4	0.7	0.3	0.4
Ever depressed for a whole week	0.3	0.3	1.3	0.5	1.1	-0.7	0.2	0.7	0.4	-0.9	0.1	0.3	-0.1	-0.0	0.6
Unable to work because of sickness or disability	0.3	0.4	1.0	0.4	0.8	0.6	-0.2	0.5	0.6	0.1	0.3	1.0	0.8	0.8	0.6
Cholesterol lowering medication	0.3	0.4	1.1	0.6	0.9	0.6	0.4	0.5	0.8	-0.1	0.6	0.7	0.4	1.1	0.7
Depressed Affect (Nagel 2018)	0.2	0.4	1.1	0.6	0.7	-0.1	-0.8	0.6	0.5	0.1	1.0	0.4	0.6	0.6	0.8
Worry (Nagel 2018)	0.2	0.3	1.6	0.2	1.2	0.0	-1.3	0.2	-0.0	0.3	-0.1	-0.2	0.3	0.6	0.3
Ulcerative Colitis (UC)	0.2	0.4	1.6	0.4	0.3	0.8	0.7	0.3	0.5	1.2	-0.1	0.5	0.7	0.6	0.4
Major Depression (MDD)	0.2	0.3	2.1	0.5	0.1	0.4	0.1	0.6	0.7	0.3	-0.1	0.3	1.4	0.0	0.3
Reaction Time	0.2	0.4	3.3	0.2	0.2	0.5	-0.7	0.3	0.1	-1.8	-0.1	-0.3	0.1	-0.2	-0.1
Neuroticism (2016)	0.2	0.3	1.1	-0.4	-0.8	-0.0	-0.2	-0.7	-0.5	0.4	-0.8	-0.3	-1.1	-0.4	-0.3
Schizophrenia (2014)	0.2	0.4	0.9	0.7	0.9	0.3	0.1	0.7	0.6	-0.8	0.5	-0.2	1.0	0.8	0.8
BMI	0.2	1.1	2.9	-1.4	-0.8	1.0	0.2	-1.2	-1.0	-0.7	-1.7	-0.4	0.5	-1.0	-1.5
Maternal smoking around birth	0.2	0.3	1.6	-0.2	-0.0	-0.4	-1.3	0.1	-0.2	-1.2	0.1	-0.4	-0.8	-0.4	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	0.7	0.5	0.2	-0.5	0.8	0.5	0.7	-0.7	0.5	0.8	-0.2	0.2	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	3.3	0.5	0.0	0.3	-0.1	0.5	0.3	-0.4	0.6	0.8	1.8	0.8	0.6
Multivitamins +/- minerals	0.2	0.2	0.5	0.6	-0.4	-0.7	0.3	0.3	0.4	-0.6	0.1	0.5	-0.7	-0.1	0.4
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	1.1	-0.4	0.3	1.0	0.3	-0.4	-0.5	0.5	0.1	0.2	0.2	0.3	-0.4
Body mass index (BMI)	0.2	0.8	1.9	-1.1	-0.5	1.4	0.2	-0.9	-0.7	-0.6	-1.3	-0.3	1.0	-0.5	-1.1
Nervous feelings	0.2	0.4	1.9	0.5	1.4	0.0	-0.6	0.7	0.5	-0.1	0.1	0.9	0.3	0.3	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.6	0.5	-0.3	0.6	0.5	0.4	0.1	-0.1	1.0	0.9	1.3	0.8	0.5
Illnesses of siblings	0.2	0.3	1.0	-0.4	-0.2	-0.3	-0.1	-0.5	-0.4	-1.0	-1.0	-0.1	0.2	-0.7	-0.4
Alcohol intake versus 10 years previously	0.2	0.3	1.6	-0.4	-0.3	-0.4	-0.4	-0.2	0.0	-0.3	-1.3	0.3	-0.5	-0.7	-0.4
Hair/balding pattern: Pattern 3	0.2	0.3	2.5	-0.3	0.2	-0.2	0.2	-0.5	-0.5	1.6	-0.3	-0.4	-0.7	-0.3	-0.2
Number of live births	0.2	0.3	1.6	0.1	0.7	-0.7	0.6	-0.1	-0.0	-1.3	-0.6	-0.4	0.4	-0.6	-0.3
Noisy workplace	0.2	0.2	1.0	-0.4	-0.5	0.1	0.3	-0.5	-0.3	-0.1	-1.0	-0.2	0.4	-0.6	-0.5
Birth weight of first child	0.2	0.3	1.5	-0.1	-0.0	0.2	-1.2	-0.3	-0.5	0.1	0.7	-1.1	0.2	0.5	-0.2
Headache pain in last month	0.2	0.4	1.0	-0.7	-0.2	-0.8	-0.2	-0.7	-0.6	-0.2	-0.9	-0.1	-1.0	-0.8	-0.7
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.9	0.9	0.8	0.6	-0.3	0.9	0.5	0.8	0.9	0.0	0.1	0.5	0.6
Exposure to tobacco smoke outside home	0.2	0.3	1.4	-0.4	-0.3	0.6	-1.2	-0.4	-0.5	-0.6	-0.5	0.0	-0.4	0.2	-0.5
Number of children fathered	0.2	0.2	0.5	-0.2	-0.0	-0.4	-0.7	-0.5	-0.5	-0.1	-0.5	-0.6	-0.6	-0.4	-0.3
Qualifications: College or University degree	0.2	0.7	2.1	-0.8	0.3	-1.1	1.5	-0.9	-0.6	-0.6	-1.1	-0.3	-1.0	-0.9	-0.7
Medication: Omeprazole	0.2	0.3	1.2	-0.1	-0.1	-0.6	0.5	0.0	0.0	-1.1	-1.0	-0.0	0.1	-0.5	-0.1
Comparative height size at age 10	0.2	1.0	3.0	-1.0	-0.5	-0.6	-1.0	-0.8	-1.0	0.5	-0.9	-1.4	-1.7	-1.1	-0.8
Leg pain on walking	0.2	0.3	0.9	0.2	-0.3	0.2	-1.0	0.5	0.4	-0.5	0.3	0.9	0.5	0.3	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.9	-0.5	-0.8	0.3	0.2	-0.2	-0.2	-1.0	-0.3	-0.4	0.2	-0.4	-0.6
Illnesses of siblings: Diabetes	0.2	0.3	0.4	0.7	0.2	0.4	0.2	0.6	0.4	-0.2	0.6	0.7	0.6	0.6	0.6
Smoking status: Previous	0.2	0.4	1.3	0.4	0.3	-0.1	1.0	0.4	0.4	-0.9	-0.1	0.6	-1.1	-0.4	0.3
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.8	0.9	0.3	-0.1	0.5	0.7	0.5	0.0	0.1	0.9	-0.4	0.1	0.7
Diabetes diagnosed by doctor	0.2	0.3	0.8	0.2	-0.6	0.9	-0.9	0.3	0.2	0.4	0.8	0.0	0.5	0.5	0.2
Ever taken oral contraceptive pill	0.2	0.2	0.7	-0.4	-0.8	0.7	-0.3	-0.3	-0.5	-0.6	0.3	0.2	0.1	0.3	-0.1
Mother’s age at death	0.2	0.2	1.4	0.1	0.3	-0.9	0.4	-0.2	-0.1	1.2	0.2	0.2	0.5	0.1	0.3
Financial situation satisfaction	0.2	0.2	1.1	0.2	0.4	0.1	0.5	0.5	0.6	-0.5	-0.5	1.0	0.3	-0.0	0.3
Commuting to job workplace: Cycle	0.2	0.2	0.6	0.4	0.5	0.4	0.8	0.3	0.2	0.1	0.6	0.1	-0.3	0.7	0.2
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.3	-0.8	-1.1	-0.8	0.3	-0.7	-0.7	-1.2	-0.1	-0.5	-0.7	-1.0	-0.8
Pain experienced in last month	0.2	0.3	1.6	0.1	-0.8	-1.3	0.6	-0.0	-0.2	-0.4	0.8	0.0	0.5	-0.6	0.1
Neuroticism (Nagel 2018)	0.1	0.3	2.7	0.1	0.7	-0.3	-1.7	0.1	-0.2	0.1	0.3	-0.2	0.6	0.3	0.3
Schizophrenia (2018)	0.1	0.2	0.6	0.4	0.7	-0.0	0.6	0.2	0.3	-0.8	-0.2	-0.1	0.6	0.3	0.4
Alzheimer’s Disease (in father)	0.1	0.1	0.4	-0.3	-0.6	0.1	-0.4	-0.4	-0.2	0.2	0.4	-0.6	0.0	-0.2	-0.2
Irritable Bowel Disease (IBD)	0.1	0.3	1.4	-0.3	-0.3	1.0	0.6	-0.2	0.0	1.2	-0.7	0.3	0.6	0.3	-0.1
Crohns Disease (2012)	0.1	0.2	0.5	-0.6	-0.7	0.7	0.3	-0.6	-0.2	0.3	-0.6	0.1	-0.5	0.0	-0.5
Blood Eosinophil Count	0.1	0.5	2.9	0.2	0.4	0.9	1.7	0.1	0.4	-1.1	-0.7	0.2	0.6	0.3	-0.2
Blood Platelet Count	0.1	0.8	6.2	-0.4	0.2	0.9	0.7	-0.6	-0.3	2.5	-0.7	0.4	0.7	0.5	-0.4
Heel T-Score	0.1	1.0	4.6	0.9	0.4	0.3	-1.1	1.3	0.7	-0.3	1.0	0.3	2.1	1.0	0.9
Waist Hip Ratio (WHR)	0.1	0.6	3.8	-0.7	-0.0	0.4	0.0	-0.5	-0.5	0.4	-0.9	-0.4	1.9	-0.4	-0.8
Systolic Blood Pressure	0.1	0.4	3.2	0.2	0.4	0.5	-0.7	-0.2	-0.3	1.8	0.6	-0.0	-0.1	0.7	0.2
Cardiovascular Disease	0.1	0.2	0.9	-0.1	0.5	0.2	-0.8	0.2	-0.0	1.0	-0.3	0.0	-0.3	0.4	0.1
Hypothyroidism (self reported)	0.1	0.2	0.7	0.5	0.6	0.1	-0.4	0.6	0.2	0.4	0.8	0.2	0.2	0.2	0.2
Type 2 Diabetes (T2D) (2018)	0.1	0.3	1.0	-0.3	-0.6	0.3	-1.0	-0.2	-0.3	0.8	0.7	-0.3	0.4	0.0	-0.3
Lung FEV1/FVC ratio	0.1	0.5	1.6	-0.2	-1.3	-0.5	0.3	-0.2	-0.5	-1.3	-0.3	-0.2	1.1	-0.7	-0.5
Neuroticism	0.1	0.2	1.3	-0.3	0.5	-0.6	-1.1	-0.2	-0.5	-0.2	-0.5	-0.4	-0.0	-0.4	-0.3
Hair Pigment	0.1	3.3	9.4	-1.6	-1.0	-1.9	-3.1	-1.6	-2.0	0.1	-1.6	-2.3	-2.0	-1.5	-1.5
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.7	-0.1	0.2	0.2	-0.7	-0.1	0.0	0.9	-0.3	0.2	0.1	0.4	0.1
Medication: Metformin	0.1	0.1	0.2	0.4	0.1	0.2	-0.4	0.4	0.3	0.1	0.4	0.4	-0.0	0.3	0.3
Impedance of leg (right)	0.1	0.6	4.2	-0.1	0.2	-2.0	-0.1	-0.1	-0.2	-1.3	-0.1	0.4	0.8	-1.0	-0.2
Fed-up feelings	0.1	0.2	1.0	0.4	0.5	0.1	0.2	0.5	0.5	0.4	1.0	0.6	0.5	0.5	0.4
Taking other prescription medications	0.1	0.2	0.7	-0.5	0.5	0.3	-0.8	-0.3	-0.3	-0.3	-0.5	0.2	0.6	-0.1	-0.4
Supplements: Glucosamine	0.1	0.1	1.0	0.2	-0.3	-0.0	-0.2	0.0	0.0	1.0	0.2	-0.5	0.4	0.2	0.3
Impedance of leg (left)	0.1	0.6	3.7	0.1	0.2	-1.9	-0.2	0.1	-0.1	-1.0	0.4	0.7	1.1	-0.7	-0.0
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.4	0.2	0.3	0.7	0.0	0.4	0.4	-0.1	-0.0	0.3	0.6	0.6	0.4
Allergy	0.1	0.2	0.9	-0.3	-0.9	-0.1	-0.1	-0.2	-0.4	0.6	0.0	-0.4	-0.9	-0.3	-0.3
Neuroticism score	0.1	0.1	0.7	-0.2	0.5	-0.5	-0.8	-0.2	-0.3	0.2	0.1	-0.1	-0.0	-0.1	-0.2
Impedance of arm (right)	0.1	0.6	3.7	0.0	0.2	-1.9	-0.3	-0.2	-0.3	-1.3	-0.1	0.4	0.5	-0.7	-0.1
Father’s age at death	0.1	0.1	0.5	0.0	0.3	-0.6	0.1	0.1	0.1	-0.2	-0.1	0.7	0.5	-0.2	0.1
Depression (self-reported)	0.1	0.1	0.3	-0.4	-0.4	-0.5	-0.0	-0.4	-0.5	0.1	-0.1	0.3	0.4	-0.2	-0.2
Impedance of arm (left)	0.1	0.5	3.5	0.4	0.3	-1.9	-0.5	0.1	-0.1	-1.1	0.1	0.2	0.4	-0.5	0.2
Loud music exposure frequency	0.1	0.1	0.4	-0.0	0.6	-0.4	-0.4	0.1	0.3	-0.5	-0.2	0.4	-0.1	-0.0	0.4
Glaucoma (self-reported)	0.1	0.1	0.2	0.3	0.5	-0.1	-0.1	0.1	-0.3	-0.3	0.1	-0.2	-0.0	-0.4	0.2
Pulse wave peak to peak time	0.1	0.1	0.3	-0.0	-0.4	0.1	0.5	0.0	0.0	-0.1	0.6	0.3	-0.0	0.2	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.4	0.3	0.4	-0.0	-0.2	0.2	0.2	0.1	0.6	0.2	-0.6	0.5	0.4
Illnesses of father: Heart disease	0.1	0.2	0.4	-0.6	-0.2	0.2	-0.5	-0.1	-0.1	-0.7	-0.4	0.4	0.6	-0.2	-0.4
Average weekly red wine intake	0.1	0.2	1.1	-0.2	-0.1	0.4	1.0	-0.1	-0.2	0.0	0.3	-0.3	-0.8	-0.3	-0.4
Mood swings	0.1	0.1	0.5	0.3	0.7	-0.3	-0.6	0.2	0.1	0.0	0.1	-0.0	-0.7	0.3	0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.9	0.4	0.0	-0.4	0.3	0.2	0.5	-0.2	0.1	1.0	0.3	0.3	0.5
Illnesses of father: High blood pressure	0.1	0.1	0.3	-0.2	0.5	0.4	0.5	0.0	-0.1	-0.0	-0.5	0.2	0.0	0.2	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.5	0.0	0.3	0.0	0.3	0.3	0.3	0.1	-0.3	0.4	0.7	0.2	0.2
Impedance of whole body	0.1	0.6	4.5	0.1	0.4	-2.1	-0.7	-0.0	-0.1	-1.1	0.2	0.4	0.6	-0.7	0.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.1	-0.2	0.3	0.2	-0.2	0.0	0.0	0.1	-0.0	0.3	0.3	-0.1	-0.2
Tanning	0.0	0.1	0.6	0.0	0.1	0.3	0.0	0.2	0.1	-0.4	0.4	0.1	-0.8	-0.3	0.0
High blood pressure	0.0	0.1	0.2	0.2	0.4	0.2	-0.4	0.1	0.1	0.4	-0.4	-0.2	0.3	0.2	0.1
Hypertension (Self-reported)	0.0	0.1	0.2	0.2	0.2	0.1	-0.5	-0.0	0.0	0.4	-0.4	-0.0	0.1	0.1	0.1

Hub : Genes

RHNO1

Models

Trait associations