Hub : Genes

RN7SKP80

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Prostate 0.190 0.074 0.00370 0.225 NA 0.168 NA 0.227 2.3e-06 NA 5.3e-05 NA 2.1e-06
2 GTEx Skin Sun Exposed Lower leg 0.117 0.046 0.00088 0.001 NA 0.014 NA 0.000 2.5e-01 NA 2.3e-02 NA 3.2e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 2.8 4.5 8.9 -3.0 0.0
Bipolar Disorder or Schizophrenia 4.5 11.1 18.4 -4.3 1.9
Depressed Affect (Nagel 2018) 0.1 0.2 0.4 -0.3 0.6
Depression (Nagel 2018) 0.0 0.0 0.0 -0.1 0.1
Intelligence (Savage-Jansen 2018) 0.2 0.6 1.0 1.0 -0.4
Neuroticism (Nagel 2018) 0.2 0.4 0.5 0.5 0.7
Schizophrenia (2018) 3.7 7.7 9.6 -3.1 2.4
Schizophrenia vs Biploar Disorder 0.8 1.0 2.1 1.4 0.1
Worry (Nagel 2018) 0.0 0.0 0.0 -0.1 -0.1
Alzheimer’s Disease (in mother) 1.0 1.1 2.2 1.5 -0.4
Alzheimer’s Disease (in father) 0.1 0.1 0.2 -0.0 -0.4
Alzheimer’s Disease (including proxy) 0.3 0.4 0.8 0.9 -0.4
Crohns Disease (2017) 0.4 0.9 1.4 -0.6 -1.2
Irritable Bowel Disease (IBD) 0.6 1.4 2.5 -1.6 -0.7
Ulcerative Colitis (UC) 0.7 1.2 2.5 -1.6 0.1
Major Depression (MDD) 2.2 2.6 4.5 -2.1 0.9
Reaction Time 0.0 0.1 0.1 0.2 -0.4
Verbal and Numeric Reasoning (VNR) 0.1 0.1 0.1 0.4 0.3
Breast Cancer 0.0 0.1 0.2 -0.0 -0.5
Ovarian Cancer 0.6 0.9 1.0 0.9 1.0
Prostate Cancer 2.5 3.5 4.9 -2.2 1.4
Age at First Birth 0.3 0.4 0.7 -0.8 -0.3
Bipolar Disorder (2011) 3.7 3.5 7.1 -2.7 0.1
Body Mass Index (BMI) (2010) 0.1 0.2 0.2 0.4 0.4
Coronary Artery Disease (CAD) 0.2 0.2 0.4 -0.6 -0.1
Crohns Disease (2012) 1.0 1.6 3.1 -1.8 -0.2
Mean Putamen Volume 0.2 0.2 0.4 0.2 -0.6
Fasting Glucose 1.0 1.2 1.2 1.1 -1.1
HbA1C 0.7 0.7 1.3 -1.1 -0.4
HDL Cholesterol 0.5 0.9 1.1 1.0 0.9
LDL Cholesterol 0.7 1.0 1.7 -1.3 0.6
Lupus 0.7 1.0 1.9 -0.4 1.4
Neuroticism (2016) 0.6 0.9 1.4 -0.6 1.2
Primary Biliary Cirrhosis 0.1 0.2 0.4 0.1 0.6
Rheumatoid Arthritis 1.1 1.4 1.5 -1.2 1.2
Schizophrenia (2014) 2.9 6.4 9.8 -3.1 1.7
Triglycerides 0.5 0.8 1.4 0.4 -1.2
Type 2 Diabetes (T2D) (2012) 0.5 0.6 0.7 -0.7 0.9
Ulcerative Colitis 2.8 4.0 5.7 -2.4 1.5
Blood Eosinophil Count 0.4 3.0 3.7 1.9 1.5
Blood Platelet Count 18.3 212.0 338.6 18.4 -9.2
Blood Red Count 1.6 15.7 24.0 -2.7 4.9
Blood White Count 2.3 17.0 17.2 -4.1 4.2
Heel T-Score 0.0 0.1 0.2 0.4 0.2
BMI 0.4 2.4 4.0 -2.0 -0.9
Height 1.8 34.9 60.2 7.8 -3.1
Waist Hip Ratio (WHR) 3.0 13.3 21.1 -4.6 2.4
Systolic Blood Pressure 0.8 3.9 7.7 -2.8 0.3
Smoking Status 0.0 0.0 0.0 0.2 0.2
Allergy or Eczema 0.8 2.2 4.2 2.1 -0.4
Cardiovascular Disease 1.6 5.3 10.6 -3.3 0.1
Hypothyroidism (self reported) 0.4 0.8 1.5 1.2 -0.4
Respiratory disease 0.6 1.3 1.4 1.2 1.2
Type 2 Diabetes (T2D) (2018) 1.2 2.3 4.5 -2.1 0.3
Lung FEV1/FVC ratio 1.5 7.7 13.2 -3.6 -1.5
Lung FVC 1.1 5.6 8.4 2.9 1.7
Neuroticism 0.0 0.1 0.2 -0.2 0.4
Chronotype (morning person) 0.7 1.6 3.0 -1.7 0.4
Hair Pigment 0.0 0.8 1.1 0.7 -1.1
Tanning 0.1 0.9 1.5 0.6 -1.2
Hand grip strength (left) 0.8 2.0 2.1 1.4 -1.4
Number of treatments/medications taken 0.2 0.4 0.7 0.2 0.8
Average weekly spirits intake 1.3 1.6 3.1 1.8 0.2
Sensitivity / hurt feelings 0.0 0.1 0.1 0.3 -0.1
Frequency of depressed mood in last 2 weeks 0.9 1.2 1.9 0.7 -1.4
Hearing difficulty/problems: Yes 0.5 0.8 0.8 0.9 0.9
Relative age of first facial hair 0.8 1.6 2.1 1.1 -1.5
Other serious medical condition/disability diagnosed by doctor 0.0 0.1 0.1 0.3 0.1
Ever used hormone-replacement therapy (HRT) 2.2 2.7 4.9 0.7 -2.2
Ever had hysterectomy (womb removed) 0.5 0.6 1.0 -1.0 -0.3
Systolic blood pressure, automated reading 0.4 1.3 2.4 -1.6 -0.4
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.2 -0.4 -0.5
Angina 1.7 2.2 2.5 1.4 -1.6
Medication for hormone replacement therapy 1.6 1.8 3.2 0.6 -1.8
Vitamin and mineral supplements 0.4 0.5 1.0 -1.0 -0.1
Supplements: Zinc 0.1 0.1 0.2 0.1 -0.4
Medication: Co-codamol 1.6 1.8 3.1 -0.8 1.8
Medication: Metformin 0.8 1.1 2.2 -0.3 1.5
Diabetes (father) 0.4 0.5 1.0 -1.0 -0.0
Diabetes (mother) 1.9 2.4 2.8 -1.5 1.7
Severe depression (siblings) 0.4 0.5 0.6 -0.6 0.8
Pack years adult smoking proportion 0.8 1.2 2.1 -1.4 -0.6
Impedance of leg (right) 0.3 1.5 1.9 1.0 -1.4
Leg fat-free mass (left) 0.3 1.6 2.9 1.7 -0.6
Trunk fat percentage 0.1 0.3 0.5 0.7 -0.4
Hand grip strength (right) 0.9 2.5 3.6 1.2 -1.9
Townsend deprivation index at recruitment 0.7 0.9 1.5 1.2 0.6
Current tobacco smoking 1.4 2.3 3.4 -1.8 1.1
Average weekly fortified wine intake 0.0 0.0 0.0 -0.1 -0.1
Maternal smoking around birth 0.3 0.5 0.8 0.4 -0.9
Fed-up feelings 0.0 0.1 0.1 0.1 -0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.7 0.8 0.8 0.9
Relative age voice broke 0.8 1.2 1.9 0.7 -1.4
Taking other prescription medications 1.6 2.4 4.2 -0.8 2.1
Age when periods started (menarche) 1.1 2.5 4.3 2.1 -0.9
Bilateral oophorectomy (both ovaries removed) 0.1 0.1 0.2 0.4 0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.2 0.4 0.8 -0.0 0.9
Tinnitus: Yes, but not now, but have in the past 0.7 0.7 1.5 0.1 1.2
Qualifications: CSEs or equivalent 1.5 2.0 2.1 -1.5 1.4
Serious illness, injury or assault to yourself 3.9 4.7 4.9 -2.2 2.1
High blood pressure 2.4 6.7 12.9 -3.6 0.6
Hayfever, allergic rhinitis or eczema 1.1 2.3 4.4 2.1 -0.4
Multivitamins +/- minerals 0.2 0.3 0.5 0.7 0.3
Stomach or abdominal pain in last month 0.3 0.4 0.8 -0.1 0.9
Supplements: Glucosamine 0.3 0.4 0.9 0.9 0.0
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 0.6 0.1 -0.8
Medication: Atenolol 0.2 0.3 0.6 -0.8 0.1
Medication: Levothyroxine sodium 0.2 0.4 0.7 -0.3 0.8
Sitting height 3.5 24.6 35.3 5.9 -3.7
Chronic bronchitis/emphysema (father) 1.1 1.2 1.7 -1.3 0.9
High blood pressure (mother) 1.2 1.7 3.5 -1.9 0.0
Body mass index (BMI) 0.3 1.2 2.4 -1.6 -0.0
Impedance of leg (left) 0.5 2.3 2.5 1.6 -1.5
Leg predicted mass (left) 0.3 1.8 3.2 1.8 -0.6
Trunk fat mass 0.2 0.7 1.0 1.0 -0.7
Waist circumference 0.5 1.9 3.3 -1.8 0.7
Number of incorrect matches in round 3.1 5.1 9.5 -3.1 0.8
Past tobacco smoking 0.1 0.2 0.3 -0.5 -0.3
Alcohol usually taken with meals 2.0 3.2 4.0 1.5 -2.0
Nervous feelings 0.1 0.1 0.2 -0.5 -0.2
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 1.0 -1.0 0.2
Hearing difficulty/problems with background noise 0.2 0.3 0.7 0.8 0.0
Hair/balding pattern: Pattern 2 0.4 0.5 0.6 0.8 -0.7
Had menopause 0.6 0.8 1.2 -1.1 0.6
Had other major operations 1.2 1.5 2.6 -0.7 1.6
Forced vital capacity (FVC) 2.0 7.8 15.6 4.0 0.0
Heel bone mineral density (BMD) T-score, automated (right) 0.7 1.6 2.7 1.6 0.6
Ever unenthusiastic/disinterested for a whole week 3.0 3.7 5.1 -2.3 1.5
Qualifications: None of the above 0.5 1.1 1.6 -0.8 1.2
Financial difficulties in last 2 years 1.3 1.8 2.3 -1.1 1.5
Mouth/teeth dental problems 2.3 3.5 6.8 2.6 0.3
Heart attack 0.5 0.7 1.2 -0.5 -1.1
Allergy 0.6 1.3 2.7 -1.6 -0.1
Pain all over the body in last month 0.0 0.0 0.0 -0.1 0.2
Diabetes (self-reported) 1.5 2.3 3.5 -1.9 1.1
Hayfever/allergic rhinitis (self-reported) 1.8 2.3 3.5 1.9 1.1
Medication: Ramipril 0.1 0.1 0.2 -0.3 0.4
Medication: Simvastatin 0.3 0.5 0.9 -1.0 -0.0
Fluid intelligence score 0.0 0.1 0.2 0.1 0.4
Illnesses of siblings 0.2 0.3 0.5 -0.0 0.7
Neuroticism score 0.0 0.0 0.1 -0.2 0.0
Weight 0.2 1.0 1.2 1.1 -0.9
Impedance of arm (right) 0.2 0.9 0.9 1.0 0.9
Arm fat percentage (right) 0.2 0.9 1.8 -1.3 0.2
Trunk fat-free mass 0.4 2.3 2.5 1.6 -1.4
Hip circumference 0.1 0.4 0.7 0.4 -0.8
Time employed in main current job 0.5 0.6 0.9 1.0 -0.5
Alcohol intake versus 10 years previously 1.1 1.7 2.9 -1.7 -0.7
Father’s age at death 0.5 0.7 1.0 0.5 -1.0
Worrier / anxious feelings 0.1 0.1 0.1 0.4 -0.4
Frequency of tiredness / lethargy in last 2 weeks 0.0 0.1 0.1 -0.3 -0.1
Falls in the last year 0.3 0.4 0.5 -0.5 0.7
Hair/balding pattern: Pattern 3 0.1 0.2 0.3 0.2 0.5
Number of live births 0.8 1.1 2.2 -0.0 -1.5
Forced expiratory volume in 1-second (FEV1) 0.9 2.9 5.8 2.4 0.0
Pulse rate 0.8 1.3 2.4 -0.4 -1.6
Happiness 0.1 0.1 0.2 0.2 -0.5
Noisy workplace 0.1 0.1 0.2 -0.4 -0.1
Qualifications: A levels/AS levels or equivalent 0.8 1.7 1.8 1.3 -1.2
Serious illness, injury or assault of a close relative in last 2 years 2.4 2.7 5.3 2.3 -0.4
Mouth/teeth dental problems: Dentures 0.4 0.6 1.3 -1.1 -0.1
Asthma 0.5 1.1 2.0 1.4 0.3
Medication: Ibuprofen (e.g. Nurofen) 8.6 11.0 12.1 3.5 -3.1
Medication: Cholesterol lowering 0.1 0.2 0.2 0.4 -0.4
Depression (self-reported) 1.3 1.6 3.0 -1.7 0.4
Medication: Lansoprazole 0.9 1.0 1.3 1.1 -0.8
Prospective memory result 1.4 1.7 2.1 -1.5 -1.1
Lung cancer (father) 0.4 0.4 0.6 -0.8 -0.5
Illnesses of mother 0.2 0.2 0.4 0.6 0.3
Forced expiratory volume in 1-second (FEV1), Best measure 1.4 4.4 8.7 3.0 -0.3
Pulse wave Arterial Stiffness index 1.5 1.7 3.2 0.4 1.8
Impedance of arm (left) 0.3 1.5 2.5 1.6 0.7
Arm fat mass (right) 0.1 0.3 0.3 -0.6 -0.6
Trunk predicted mass 0.4 2.4 2.7 1.6 -1.5
Standing height 1.9 19.2 33.5 5.8 -2.2
Length of working week for main job 0.4 0.4 0.6 0.5 0.8
Exposure to tobacco smoke at home 0.1 0.1 0.1 -0.0 -0.4
Breastfed as a baby 0.0 0.1 0.1 0.0 0.3
Tense / ‘highly strung’ 1.6 2.7 4.8 0.7 -2.2
Seen doctor (GP) for nerves, anxiety, tension or depression 2.1 3.2 6.2 -2.5 0.5
Hair/balding pattern: Pattern 4 0.2 0.6 1.0 -0.3 1.0
Birth weight of first child 0.7 1.2 1.5 1.0 -1.2
Peak expiratory flow (PEF) 0.1 0.3 0.4 0.6 0.3
Pulse wave reflection index 1.1 1.3 2.2 -0.7 1.5
Ever highly irritable/argumentative for 2 days 0.6 0.7 1.0 -0.6 1.0
Loud music exposure frequency 0.2 0.3 0.4 0.4 -0.6
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 0.9 1.0 -0.5
Mouth/teeth dental problems: Bleeding gums 0.6 0.8 0.9 -0.9 -0.9
Blood clot in the leg (DVT) 0.5 0.7 0.8 -0.8 0.9
Medication: Paracetamol 0.7 1.1 1.9 1.4 -0.6
Headache pain in last month 0.3 0.6 1.0 -1.0 0.5
Medication for cholesterol, blood pressure or diabetes 0.1 0.2 0.3 0.2 0.6
Glaucoma (self-reported) 1.7 1.9 2.4 -1.5 1.2
Gout (self-reported) 1.7 2.3 3.5 1.0 -1.9
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 0.5 0.7 0.0
Medication: Amlodipine 2.9 4.1 5.5 -2.3 1.7
Medication: Ventolin 100micrograms inhaler 1.1 1.4 2.1 1.5 0.9
Birth weight 0.1 0.1 0.2 0.3 0.5
Chronic bronchitis/emphysema (mother) 0.5 0.6 1.1 -1.1 0.2
High blood pressure (siblings) 0.4 0.6 0.8 -0.9 -0.6
Forced vital capacity (FVC), Best measure 2.4 8.6 17.2 4.1 -0.3
Body fat percentage 0.0 0.1 0.2 -0.1 -0.4
Leg fat percentage (right) 0.2 0.7 1.0 -1.0 -0.6
Arm fat-free mass (right) 0.5 2.5 2.9 1.7 -1.4
Exposure to tobacco smoke outside home 0.1 0.1 0.2 -0.3 0.4
Comparative body size at age 10 1.7 4.8 7.5 -2.7 1.4
Number of full brothers 0.6 0.8 0.8 0.9 -0.8
Worry too long after embarrassment 0.8 1.3 2.6 0.2 1.6
Seen a psychiatrist for nerves, anxiety, tension or depression 4.8 6.2 9.4 -3.1 1.7
Wheeze or whistling in the chest in last year 0.2 0.4 0.7 0.8 0.4
Number of children fathered 0.7 0.8 1.5 0.4 -1.2
Reason for reducing amount of alcohol drunk: Health precaution 0.0 0.0 0.0 0.1 -0.1
Age at first live birth 2.5 4.5 4.8 2.2 -2.1
Pulse wave peak to peak time 1.8 2.1 4.3 0.1 -2.1
Health satisfaction 0.0 0.0 0.0 -0.2 -0.2
Shortness of breath walking on level ground 0.0 0.0 0.0 -0.1 -0.0
Qualifications: College or University degree 2.0 6.4 8.5 2.9 -2.0
Eye problems/disorders: None of the above 1.6 1.9 2.8 1.0 -1.7
Mouth/teeth dental problems: Loose teeth 1.2 1.4 2.7 -1.7 0.2
Emphysema/chronic bronchitis 4.3 4.8 5.9 -2.4 1.9
Medication for pain relief, constipation, heartburn 2.4 4.0 6.8 -2.6 1.1
Neck or shoulder pain in last month 0.0 0.0 0.1 -0.3 -0.0
Medication: Blood pressure 0.2 0.3 0.6 -0.8 -0.0
Angina (self-reported) 2.4 3.1 3.7 1.6 -1.9
Migraine (self-reported) 2.2 2.7 3.2 -1.5 -1.8
Medication: Ibuprofen 7.1 8.5 8.9 3.0 -2.8
Medication: Allopurinol 0.7 1.0 1.8 -0.4 -1.3
Medication: Omeprazole 0.2 0.2 0.3 -0.4 0.6
Medication: Seretide 50 evohaler 0.1 0.1 0.1 -0.3 0.1
Mean time to correctly identify matches 0.2 0.4 0.7 0.3 -0.9
Heart disease (mother) 0.1 0.1 0.1 0.4 0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.6 1.0 -1.0 -0.3
Whole body fat mass 0.1 0.4 0.5 0.6 -0.7
Leg fat mass (right) 0.1 0.5 1.0 -0.2 -1.0
Arm predicted mass (right) 0.5 2.6 3.6 1.9 -1.3
Pulse rate, automated reading 0.2 0.5 0.6 -0.6 -0.8
Alcohol intake frequency. 4.2 9.8 15.9 -4.0 1.9
Comparative height size at age 10 0.7 4.0 7.5 2.7 -0.7
Number of full sisters 4.1 5.0 7.4 2.7 -1.6
Suffer from ‘nerves’ 0.1 0.1 0.2 -0.4 -0.3
Overall health rating 0.3 0.7 0.9 -0.9 0.7
Chest pain or discomfort 0.8 1.1 2.1 1.4 -0.3
Had major operations 2.0 2.3 3.4 -1.1 1.9
Age at last live birth 2.3 3.4 5.0 2.2 -1.3
Family relationship satisfaction 0.2 0.3 0.4 0.6 -0.4
Leg pain on walking 0.2 0.2 0.3 -0.4 0.6
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 2.4 -0.5 1.5
Commuting to job workplace: Car/motor vehicle 0.3 0.3 0.4 -0.4 0.7
Illness, injury, bereavement, stress in last 2 years 1.7 2.0 2.2 1.5 -1.4
Medication: Aspirin 0.5 0.6 1.0 0.5 1.0
Supplements: Vitamin C 0.1 0.1 0.2 0.0 -0.4
Knee pain experienced in last month 1.9 3.0 5.6 -0.6 2.4
Hypertension (Self-reported) 2.4 6.6 13.0 -3.6 0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.3 0.4 -0.6 -0.3
Illnesses of father: Heart disease 0.9 1.2 2.3 1.5 0.3
Illnesses of siblings: Diabetes 0.3 0.4 0.8 -0.3 0.9
Smoking status: Previous 0.8 1.2 2.0 1.4 -0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.7 1.5 2.0 1.4 -1.0
Whole body fat-free mass 0.4 2.3 3.3 1.8 -1.1
Leg fat-free mass (right) 0.4 2.0 3.8 2.0 -0.5
Arm fat percentage (left) 0.1 0.5 1.0 -1.0 0.2
Average weekly red wine intake 1.4 2.1 3.9 2.0 -0.5
Handedness (chirality/laterality): Left-handed 1.6 2.0 3.5 0.6 -1.9
Mood swings 0.1 0.2 0.4 0.1 -0.6
Loneliness, isolation 0.2 0.3 0.4 0.6 0.3
Long-standing illness, disability or infirmity 0.3 0.5 0.9 -0.0 1.0
Ever had bowel cancer screening 1.5 1.7 2.3 1.5 -1.1
Diabetes diagnosed by doctor 1.3 2.2 3.5 -1.9 0.9
Ever had stillbirth, spontaneous miscarriage or termination 1.2 1.2 1.4 1.0 -1.2
Friendships satisfaction 0.5 0.6 1.0 -0.4 1.0
Qualifications: nursing, teaching 0.2 0.3 0.6 0.1 -0.8
Commuting to job workplace: Walk 1.4 1.5 2.2 -0.9 1.5
Eye problems/disorders: Cataract 1.2 1.3 2.0 -1.4 0.8
Mouth/teeth dental problems: Mouth ulcers 0.0 0.0 0.1 0.2 -0.2
Medication for cholesterol 1.6 2.5 4.7 2.2 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.9 1.1 1.3 -0.9 -1.1
Back pain experienced in last month 0.4 0.5 0.9 0.4 0.9
Mineral and other dietary supplements 1.5 2.0 2.6 -1.6 1.2
Breast cancer (self-reported) 0.1 0.1 0.2 0.2 0.5
Asthma (self-reported) 0.4 0.8 1.4 1.2 0.3
Osteoporosis (self-reported) 0.0 0.0 0.0 0.1 0.2
Osteoarthritis (self-reported) 0.1 0.1 0.1 -0.2 0.3
Medication: Aspirin 0.3 0.4 0.8 -0.1 0.9
Medication: Gliclazide 0.1 0.1 0.2 -0.3 0.4
Illnesses of father: None of the above (group 1) 0.8 1.0 1.0 1.0 -1.0
Smoking status: Current 1.5 2.4 3.6 -1.9 1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 0.7 0.8 0.5
Whole body water mass 0.4 2.2 3.2 1.8 -1.1
Leg predicted mass (right) 0.4 2.1 3.9 2.0 -0.6
Arm fat mass (left) 0.0 0.2 0.2 -0.4 -0.4
Number of self-reported non-cancer illnesses 1.2 2.1 3.8 -2.0 0.6
Average weekly champagne plus white wine intake 1.6 2.2 2.9 1.2 -1.7
Miserableness 0.5 0.9 1.7 0.3 -1.3
Guilty feelings 1.5 2.3 3.7 1.9 0.9
Wears glasses or contact lenses 1.2 1.4 1.6 1.1 -1.3
Ever taken oral contraceptive pill 1.4 1.6 1.7 -1.2 1.3
Hearing aid user 0.3 0.3 0.6 0.8 -0.0
Mother’s age at death 3.6 4.4 5.3 1.9 -2.3
Financial situation satisfaction 0.4 0.6 1.0 1.0 0.4
Tinnitus: Yes, now most or all of the time 0.4 0.4 0.7 0.4 0.9
Commuting to job workplace: Public transport 1.2 1.4 1.9 -1.0 1.4
Eye problems/disorders: Glaucoma 1.9 2.2 2.4 -1.4 1.6
Medication: Blood pressure 2.5 4.7 8.6 -2.9 0.9
Pain type(s) experienced in last month: Hip pain 0.0 0.0 0.1 -0.2 -0.1
Supplements: Fish oil (including cod liver oil) 1.8 2.3 4.0 2.0 -0.8
High cholesterol (Self-reported) 0.2 0.3 0.6 0.1 0.8
Medication: Bendroflumethiazide 2.0 3.1 6.1 -2.5 -0.2
Medication: Paracetamol 1.6 2.4 3.0 1.4 -1.7
Medication: Lisinopril 2.9 3.7 5.7 -2.4 1.3
Medication: Atorvastatin 0.4 0.5 0.9 -0.3 0.9
Illnesses of father: High blood pressure 0.4 0.5 0.6 -0.6 -0.8
Alcohol drinker status: Never 0.9 1.1 2.2 -1.5 -0.0
Ever smoked 0.1 0.2 0.4 0.2 0.6
Basal metabolic rate 0.4 2.4 3.0 1.7 -1.3
Leg fat percentage (left) 0.1 0.5 0.8 -0.9 -0.5
Arm fat-free mass (left) 0.4 2.1 2.8 1.2 -1.7
Number of operations (self-reported) 1.5 2.2 2.9 -1.7 1.2
Average weekly beer plus cider intake 0.0 0.1 0.1 0.1 -0.4
Irritability 0.4 0.8 1.5 0.2 -1.2
Risk taking 0.4 0.6 0.9 0.9 -0.5
Ever had prostate specific antigen (PSA) test 0.1 0.1 0.2 0.4 0.1
Fractured/broken bones in last 5 years 0.1 0.1 0.2 -0.4 0.4
Age started oral contraceptive pill 0.6 0.8 1.5 -0.2 -1.2
Diastolic blood pressure, automated reading 0.6 1.8 2.4 -1.6 -1.1
Ever depressed for a whole week 5.8 7.1 12.9 -3.6 1.2
Unable to work because of sickness or disability 4.1 5.3 5.7 -2.4 2.2
Commuting to job workplace: Cycle 1.6 2.0 3.8 0.4 -1.9
Myopia 2.7 4.0 7.5 2.7 0.7
Vascular/heart problems diagnosed by doctor 1.8 5.0 10.0 3.2 0.3
Cholesterol lowering medication 0.4 0.6 0.7 -0.8 0.7
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 0.7 -0.3 0.8
Pain experienced in last month 0.3 0.5 0.9 -0.2 -1.0
Supplements: Calcium 0.1 0.1 0.1 0.3 -0.3
Basal cell carcinoma (self-reported) 0.3 0.3 0.6 0.8 -0.1
Heart attack/myocardial infarction (self-reported) 0.7 0.9 1.4 -0.7 -1.2
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 1.2 -0.6 1.1
Heart disease (siblings) 0.9 1.2 1.4 1.2 -1.0
Alcohol drinker status: Previous 1.7 2.0 2.4 -1.3 1.5
Pack years of smoking 0.7 1.0 1.3 -1.1 -0.8
Impedance of whole body 0.3 1.5 2.9 1.7 -0.3
Leg fat mass (left) 0.1 0.4 0.9 -0.1 -0.9
Arm predicted mass (left) 0.3 1.6 2.1 1.1 -1.5