TWAS hub - RNF167

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0620	0.0240	7.2e-04	0.020	0.015	0.026	0.016	0.021	1.4e-03	5.8e-03	3.1e-04	4.1e-03	1.2e-03
2	GTEx	Adipose Subcutaneous	0.1360	0.0420	5.6e-04	0.071	NA	0.029	NA	0.040	1.9e-06	NA	1.8e-03	NA	3.2e-04
3	GTEx	Artery Aorta	0.1290	0.0460	1.8e-03	0.076	NA	0.028	NA	0.039	5.4e-05	NA	1.1e-02	NA	3.4e-03
4	GTEx	Artery Tibial	0.1074	0.0368	1.2e-03	0.018	NA	0.045	NA	0.035	1.3e-02	NA	1.8e-04	NA	8.4e-04
5	GTEx	Cells Transformed fibroblasts	0.1110	0.0440	4.7e-03	0.074	NA	0.036	NA	0.064	3.2e-06	NA	9.7e-04	NA	1.4e-05
6	GTEx	Esophagus Muscularis	0.1820	0.0540	8.6e-05	0.020	NA	0.024	NA	0.029	2.0e-02	NA	1.3e-02	NA	6.8e-03
7	GTEx	Muscle Skeletal	0.0834	0.0331	3.2e-03	0.006	NA	0.000	NA	0.002	7.1e-02	NA	2.8e-01	NA	1.8e-01
8	METSIM	Adipose	0.0663	0.0262	4.9e-04	0.008	0.012	0.002	0.011	0.010	1.9e-02	5.0e-03	1.2e-01	6.3e-03	1.1e-02
9	NTR	Blood	0.0332	0.0108	1.4e-04	0.010	0.007	0.006	0.008	0.007	1.9e-04	1.6e-03	3.5e-03	1.3e-03	1.5e-03
10	YFS	Blood	0.2457	0.0299	0.0e+00	0.336	0.307	0.345	0.336	0.338	2.7e-114	7.3e-103	2.5e-118	1.4e-114	2.1e-115
11	TCGA	Pheochromocytoma and Paraganglioma	0.1870	0.0790	1.2e-03	0.114	0.084	0.068	NA	0.081	2.8e-05	3.2e-04	1.1e-03	NA	4.0e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Depression (Nagel 2018)	4.6	6.9	11.8	3.4	2.8	2.9	3.1	2.8	2.3	-2.1	3.3	1.6	-1.9	1.8
Chronic bronchitis/emphysema (mother)	4.0	4.6	11.5	-0.7	-2.9	-2.6	-2.5	-2.6	-2.4	0.7	-2.0	-0.5	0.2	-3.4
Illnesses of siblings: Diabetes	3.8	4.6	7.2	-1.9	-1.7	-1.4	-2.6	-1.7	-2.7	2.1	-2.6	-2.5	1.8	-2.3
Lung cancer (father)	3.7	4.3	10.6	-0.4	2.5	3.0	1.7	3.3	2.5	1.0	1.4	-0.8	1.3	2.7
HbA1C	3.4	3.8	11.3	-1.4	1.8	1.7	-1.0	1.5	0.9	3.3	-0.6	-2.3	3.4	1.3
Ever smoked	3.2	5.6	15.0	-3.4	1.5	1.6	-1.3	1.7	0.7	3.7	-1.5	-2.6	3.9	1.7
Medication: Allopurinol	3.0	4.0	8.6	-1.7	-2.1	-1.8	-2.4	-1.7	-1.4	2.9	-1.5	-2.9	1.6	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.8	3.8	8.9	1.4	2.4	2.3	3.0	2.6	1.5	-1.2	2.1	0.7	-0.9	1.7
Alzheimer’s Disease (in father)	2.7	2.9	8.4	0.8	1.5	1.5	2.9	1.4	2.4	-1.2	1.9	1.7	-1.3	0.9
Medication: Levothyroxine sodium	2.7	4.6	7.8	-2.0	-2.0	-2.8	-2.6	-2.3	-1.8	2.0	-1.9	-1.4	2.5	-2.1
Gout (self-reported)	2.7	3.8	8.5	-0.9	-2.1	-2.1	-2.9	-2.1	-2.1	2.2	-1.0	-2.2	0.9	-1.6
Rheumatoid Arthritis	2.5	3.4	9.4	-3.1	1.4	1.1	-0.8	1.3	0.7	2.4	-2.0	-1.7	2.8	1.3
Blood Platelet Count	2.5	28.9	80.5	6.1	5.2	0.1	3.4	1.8	1.0	-6.5	9.0	6.2	-7.6	-4.4
Smoking Status	2.5	6.1	16.0	-3.1	1.8	1.7	0.5	1.9	2.0	3.6	-0.9	-3.1	4.0	2.0
Mineral and other dietary supplements	2.5	3.4	11.6	-2.7	-1.3	-0.7	-0.4	-0.5	0.6	2.5	-3.4	-2.0	2.4	0.0
Alzheimer’s Disease (including proxy)	2.4	3.4	13.9	-0.8	1.3	0.6	3.5	1.3	3.7	-0.3	1.1	2.0	-0.6	1.0
Taking other prescription medications	2.4	3.7	8.4	-2.1	-0.5	-1.5	-2.2	-0.9	-1.7	2.6	-1.9	-2.9	2.4	-1.1
Past tobacco smoking	2.4	4.4	12.4	3.2	-0.9	-0.8	1.0	-1.4	-0.4	-3.3	1.5	2.3	-3.5	-1.5
Age started oral contraceptive pill	2.4	3.0	5.7	1.7	1.4	1.8	2.3	2.1	1.7	-0.9	2.4	0.6	-0.9	2.2
Lupus	2.3	3.5	8.9	-2.7	-0.2	-0.0	-1.8	0.5	-0.7	2.9	-1.8	-3.0	2.5	-0.8
Ulcerative Colitis	2.3	3.4	9.5	3.1	0.6	1.2	1.1	0.6	0.2	-2.3	2.8	2.0	-2.3	1.4
Financial situation satisfaction	2.3	2.8	8.1	2.8	0.4	0.6	1.4	0.6	0.7	-2.5	1.8	2.0	-2.4	0.6
Prostate Cancer	2.2	3.1	8.1	-0.1	2.1	2.2	2.5	2.1	2.8	-0.3	0.5	1.1	0.5	1.9
Medication for hormone replacement therapy	2.2	2.5	4.5	-1.5	-1.5	-1.1	-2.1	-2.0	-1.8	1.0	-1.8	-0.8	1.6	-1.7
Current tobacco smoking	2.2	3.6	11.4	-2.1	1.4	1.2	0.2	1.2	1.4	2.6	-1.2	-3.4	2.8	0.9
High blood pressure (siblings)	2.2	3.2	6.5	-1.9	-1.4	-1.5	-1.8	-1.9	-2.5	1.1	-1.6	-2.2	0.5	-2.4
Frequency of tenseness / restlessness in last 2 weeks	2.1	3.3	10.2	2.7	0.4	-0.1	2.0	0.4	0.1	-3.2	2.4	1.5	-2.5	0.2
Pulse rate, automated reading	2.1	6.9	18.3	4.2	0.4	-0.5	1.6	0.2	-0.4	-4.3	3.8	2.3	-4.2	-0.5
Average weekly red wine intake	2.1	3.1	11.1	1.8	0.6	-0.2	1.2	0.3	-1.1	-2.4	3.3	2.2	-2.5	0.2
Risk taking	2.1	3.1	6.8	-1.5	1.9	1.8	1.1	2.1	2.6	1.9	-0.0	-0.4	2.1	2.1
Ever used hormone-replacement therapy (HRT)	2.0	2.5	5.0	-0.6	2.1	2.1	1.0	2.2	1.9	1.4	0.7	-1.1	1.3	1.8
Medication: Atenolol	2.0	2.6	7.8	2.8	-0.0	0.3	0.8	-0.2	-0.4	-2.5	2.2	1.0	-2.7	-0.4
Hearing difficulty/problems with background noise	2.0	3.1	9.1	1.6	1.9	1.4	2.1	1.8	2.0	-0.8	3.0	0.8	-1.0	1.8
Number of children fathered	2.0	2.2	7.0	-2.7	0.9	1.0	0.3	1.4	2.2	1.8	0.0	-0.2	2.1	1.2
Age at last live birth	2.0	2.9	8.8	-0.7	1.4	1.7	2.3	2.0	3.0	0.3	0.4	0.5	0.8	2.8
Smoking status: Current	2.0	3.1	9.4	-1.7	1.4	1.4	0.3	1.2	1.4	2.4	-0.7	-3.1	2.6	1.0
Schizophrenia vs Biploar Disorder	1.9	2.4	5.3	2.0	1.5	1.6	0.9	1.2	0.4	-2.3	1.1	2.0	-2.0	1.2
Qualifications: CSEs or equivalent	1.9	2.5	6.9	-2.0	-0.7	-1.3	-1.7	-0.9	-0.4	1.8	-1.6	-2.6	1.4	-1.9
Osteoporosis (self-reported)	1.9	2.4	5.7	-0.4	-1.5	-1.6	-2.2	-1.7	-2.4	-0.0	-1.0	-1.7	-0.0	-2.0
Eye problems/disorders: Glaucoma	1.8	2.1	6.2	-2.4	0.3	0.7	-0.2	0.3	0.3	2.2	-1.1	-2.5	2.0	0.4
Hypothyroidism (self reported)	1.7	4.0	7.9	-1.6	-1.9	-2.8	-2.2	-2.3	-1.8	1.8	-1.9	-1.2	2.0	-2.0
Hearing difficulty/problems: Yes	1.7	2.6	11.7	0.9	2.0	1.5	1.7	1.7	0.8	-0.5	3.4	0.4	-0.1	1.6
Average weekly fortified wine intake	1.7	2.0	4.7	1.8	-0.0	0.1	0.5	-0.8	-0.6	-2.2	1.4	1.9	-2.0	-1.6
Multivitamins +/- minerals	1.7	2.2	9.3	3.0	0.4	0.5	-0.2	-0.2	-1.0	-2.4	1.2	1.1	-2.2	0.1
Father’s age at death	1.7	2.3	7.0	2.6	0.1	0.4	1.0	0.4	1.1	-2.0	1.6	1.9	-2.2	0.8
Supplements: Fish oil (including cod liver oil)	1.7	2.2	6.4	2.5	1.4	1.1	-0.5	0.6	-0.7	-1.9	2.3	1.2	-1.7	0.3
Hair/balding pattern: Pattern 2	1.6	2.1	7.4	-0.8	1.6	1.4	1.9	1.7	2.7	0.6	-0.1	0.6	0.7	1.7
Hypothyroidism/myxoedema (self-reported)	1.6	3.2	8.6	-1.2	-1.9	-2.9	-2.0	-2.3	-1.2	1.1	-2.0	-0.3	1.2	-2.1
Qualifications: nursing, teaching	1.6	2.5	4.9	1.3	2.0	2.2	1.7	1.6	1.2	-1.5	2.2	1.4	-0.6	0.9
Commuting to job workplace: Walk	1.6	1.8	3.3	1.8	-1.6	-0.7	-0.3	-1.5	-1.5	-1.6	-1.2	-1.0	-1.1	-1.5
Ulcerative Colitis (UC)	1.5	2.8	9.0	3.0	-0.2	0.3	0.9	0.1	-0.3	-2.2	3.0	1.4	-2.1	0.8
Verbal and Numeric Reasoning (VNR)	1.5	3.7	8.9	-3.0	-1.2	-0.9	-1.7	-1.4	-1.2	2.2	-2.7	-1.6	2.4	-1.6
Ovarian Cancer	1.5	2.0	4.4	-0.2	-1.9	-1.9	-0.3	-2.1	-1.1	-1.7	-0.8	1.2	-1.1	-1.4
Neuroticism (2016)	1.5	2.2	6.7	2.3	-0.3	-0.6	1.6	0.1	-0.5	-2.5	1.0	1.2	-2.6	-0.0
Eye problems/disorders: Diabetes related eye disease	1.5	1.6	7.0	-1.1	-1.8	-1.5	-0.4	-1.9	-0.5	-0.3	-0.4	0.1	0.1	-2.6
Glaucoma (self-reported)	1.5	1.8	4.6	-2.2	0.0	0.4	-0.9	-0.1	-0.0	1.9	-1.8	-2.1	1.7	0.3
Health satisfaction	1.5	1.9	5.7	2.4	1.2	1.1	1.2	1.2	0.4	-1.9	1.6	0.8	-1.6	0.8
Commuting to job workplace: Car/motor vehicle	1.5	1.7	5.6	-2.4	0.4	-0.2	0.1	0.5	1.4	1.7	-2.1	-0.2	1.7	0.6
Smoking status: Previous	1.5	2.2	7.1	-2.7	0.1	-0.1	-1.2	0.6	-0.4	2.2	-1.5	-1.1	2.4	0.7
Medication: Co-codamol	1.4	1.7	7.7	1.4	1.7	1.6	0.6	1.3	0.3	-0.4	2.8	0.6	-0.4	0.7
Heart attack	1.4	1.8	4.8	0.6	-1.9	-1.2	-1.5	-1.8	-1.5	-0.3	-1.0	-0.5	-0.4	-2.2
Diabetes (self-reported)	1.4	2.1	7.0	-2.6	-1.4	-0.7	-1.2	-1.3	-0.1	1.2	-1.4	-0.7	1.4	-2.1
Prospective memory result	1.4	1.7	4.1	-0.8	1.9	1.8	0.5	2.0	1.2	0.8	-0.0	-1.1	0.7	1.6
Eye problems/disorders: None of the above	1.4	1.6	4.8	2.2	-0.5	-0.9	-0.1	-0.4	-0.2	-1.9	0.5	2.1	-1.9	0.4
Heart attack/myocardial infarction (self-reported)	1.4	1.8	4.5	0.6	-1.9	-1.2	-1.5	-1.8	-1.6	-0.2	-1.1	-0.7	-0.4	-2.1
Alcohol drinker status: Previous	1.4	1.5	4.5	-0.5	-2.1	-2.0	-0.4	-1.7	-1.0	-0.4	-0.8	-0.3	-0.4	-1.7
Depressed Affect (Nagel 2018)	1.3	2.6	7.2	2.2	1.0	1.1	2.7	1.6	1.6	-1.5	2.0	0.8	-1.3	0.9
Worry (Nagel 2018)	1.3	2.7	9.4	3.1	-0.2	0.5	0.3	0.3	1.1	-2.9	1.6	1.5	-2.3	0.2
Pulse rate	1.3	2.1	7.1	1.3	1.8	1.2	1.7	1.4	0.7	-1.5	2.7	0.5	-1.3	0.6
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	3.9	-1.2	0.8	0.3	0.7	1.0	1.7	2.0	-0.9	0.5	1.5	1.8
Number of full sisters	1.3	1.6	4.5	0.5	-1.2	-1.8	-1.8	-1.5	-2.1	-0.3	-0.4	0.9	-0.2	-1.3
Illness, injury, bereavement, stress in last 2 years	1.3	1.6	5.2	1.0	-1.3	-0.5	-1.7	-1.4	-2.3	-0.1	-1.0	-1.5	-0.5	-1.3
Supplements: Calcium	1.3	1.4	4.8	1.1	-0.7	-0.6	-0.4	-0.5	-0.9	-2.0	0.8	1.7	-2.2	-0.7
Fasting Glucose	1.2	1.5	4.0	-0.1	1.5	1.2	1.9	1.2	2.0	-0.0	0.7	0.6	0.5	1.4
Number of treatments/medications taken	1.2	2.1	3.4	-1.3	-0.7	-1.8	-1.7	-1.4	-1.6	1.5	-0.6	-1.7	1.3	-1.8
Other serious medical condition/disability diagnosed by doctor	1.2	1.6	4.0	-2.0	1.7	0.2	1.7	1.1	1.3	1.3	-0.9	0.1	1.4	0.8
Medication: Metformin	1.2	1.6	5.9	-2.4	-0.3	-0.1	-0.7	-0.7	0.4	0.8	-1.4	-1.8	1.3	-1.8
Diabetes (father)	1.2	1.4	3.9	-0.1	-1.9	-1.2	-1.2	-2.0	-1.3	0.1	-0.4	-0.7	-0.3	-1.7
Pain all over the body in last month	1.2	1.3	3.4	1.1	0.6	0.5	0.6	-0.2	0.4	-1.6	1.8	1.6	-1.4	-1.0
Pulse wave reflection index	1.2	1.4	4.9	-1.1	-0.1	0.6	-1.0	-0.3	-0.6	2.0	-1.4	-1.3	2.2	-0.2
Birth weight	1.2	2.6	6.1	2.3	0.7	0.1	1.6	0.8	-0.3	-1.4	2.5	2.3	-2.2	1.1
Neck or shoulder pain in last month	1.2	1.7	3.4	-0.8	-0.9	-1.6	-1.7	-0.8	-1.7	1.0	-1.9	-1.1	1.7	-0.0
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	3.3	-0.5	1.3	1.4	1.6	1.1	1.8	-0.7	1.7	0.3	-0.2	1.0
Diabetes diagnosed by doctor	1.2	2.0	7.8	-2.8	-0.9	-0.5	-0.7	-1.1	0.4	1.4	-1.4	-1.4	1.7	-1.7
Illnesses of father: None of the above (group 1)	1.2	1.5	2.9	0.5	-1.3	-1.7	-0.6	-1.3	-1.6	-1.4	-0.0	1.2	-1.4	-1.4
Leg fat percentage (left)	1.2	4.3	15.5	-3.4	1.9	0.9	2.1	1.6	3.9	1.2	1.8	0.7	1.7	0.3
Alzheimer’s Disease (in mother)	1.1	1.3	7.1	-0.8	0.8	-0.0	1.8	0.9	2.7	0.2	0.3	0.2	0.3	1.3
Reaction Time	1.1	2.1	6.2	1.4	0.6	-0.1	1.0	0.4	0.9	-1.7	2.2	2.5	-2.2	-0.5
Blood White Count	1.1	7.9	26.2	-5.1	-1.6	-2.4	-2.5	-2.4	1.0	1.0	3.0	2.2	1.3	-4.7
Average weekly spirits intake	1.1	1.4	4.4	0.3	1.9	0.4	0.6	1.6	2.1	0.6	0.8	1.4	0.2	1.2
Hayfever, allergic rhinitis or eczema	1.1	2.4	6.0	0.6	2.1	1.3	2.3	1.6	2.4	-0.9	1.7	0.9	-0.4	1.0
Alcohol usually taken with meals	1.1	1.8	4.6	1.6	-0.6	-0.7	-0.3	-0.6	-1.8	-1.6	1.6	2.1	-1.9	-0.1
Illnesses of siblings	1.1	1.5	4.6	1.2	0.6	0.5	1.9	0.8	2.1	-0.6	0.6	1.7	-0.5	1.5
Falls in the last year	1.1	1.5	2.6	-0.7	1.6	0.7	1.4	1.4	0.9	1.1	1.3	-1.6	1.2	1.0
Illnesses of mother	1.1	1.3	3.8	1.6	0.1	-0.4	1.0	-0.3	0.7	-1.9	0.6	1.5	-1.9	0.3
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	2.5	0.9	-1.2	-1.0	-1.5	-1.3	-1.6	-0.6	-0.2	0.7	-1.3	-1.2
Mouth/teeth dental problems: Loose teeth	1.1	1.3	3.6	1.7	1.0	0.8	0.9	0.7	0.7	-1.9	0.9	0.9	-1.4	1.0
Mean time to correctly identify matches	1.1	2.2	5.3	1.8	1.1	0.4	0.8	0.8	0.6	-1.8	2.3	2.0	-2.2	-0.4
Suffer from ‘nerves’	1.1	1.7	4.0	1.8	-0.2	0.0	0.5	0.4	1.5	-1.7	1.8	1.6	-2.0	0.1
Mouth/teeth dental problems: Mouth ulcers	1.1	1.7	5.5	0.1	1.3	1.5	0.8	1.6	1.9	-0.0	2.3	0.7	0.3	1.4
Hearing aid user	1.1	1.2	4.9	0.4	-0.7	-0.8	-1.3	-1.1	-2.2	-1.1	0.2	0.4	-1.1	-1.3
Number of operations (self-reported)	1.1	1.7	3.7	0.7	1.8	1.9	1.1	1.9	1.7	0.2	0.7	0.6	0.6	1.5
Fractured/broken bones in last 5 years	1.1	1.4	3.6	-1.9	-0.4	-0.7	-1.2	-0.5	-0.9	1.6	-1.9	-1.2	1.1	-0.3
Breast Cancer	1.0	2.4	5.2	-0.5	-2.3	-1.9	-1.7	-1.9	-2.1	0.8	-1.9	-1.0	0.5	-0.9
BMI	1.0	5.7	21.3	-3.1	2.0	0.3	3.2	1.7	4.6	0.7	3.0	1.9	1.3	0.3
Type 2 Diabetes (T2D) (2018)	1.0	1.9	5.8	-2.4	0.4	0.4	0.1	0.3	1.8	1.7	-1.4	-1.2	2.3	-0.3
Frequency of depressed mood in last 2 weeks	1.0	1.4	4.6	2.1	0.9	1.2	1.0	1.2	1.1	-0.4	1.4	1.3	-0.6	0.6
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.3	-0.8	-1.3	-1.5	-0.9	-1.3	-1.2	0.7	-1.1	-0.5	0.1	-1.4
High blood pressure (mother)	1.0	1.4	4.1	-0.2	1.7	2.0	0.8	1.7	1.0	0.8	-0.2	-0.4	0.6	1.5
Body mass index (BMI)	1.0	4.3	16.2	-3.3	1.8	0.5	2.1	1.3	4.0	1.3	2.1	1.3	1.8	0.1
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	6.8	0.0	1.4	2.1	2.2	1.8	2.6	0.3	1.2	0.3	0.4	1.8
Medication: Ramipril	1.0	1.2	2.7	-0.4	-1.0	-1.1	-1.4	-1.3	-1.5	0.3	-0.8	-1.3	0.6	-1.6
Impedance of arm (right)	1.0	4.9	17.0	2.6	-2.1	-1.3	-2.3	-2.3	-4.1	-1.7	-0.7	-1.1	-2.1	-2.1
Asthma	1.0	2.0	4.2	-2.0	-0.4	-1.0	-2.0	-0.6	-0.9	1.8	-1.0	-2.0	1.7	-0.5
Tense / ‘highly strung’	1.0	1.7	3.8	1.9	0.7	1.2	1.4	1.3	1.5	-1.7	1.1	0.6	-1.2	1.0
Birth weight of first child	1.0	1.8	5.7	1.5	1.0	0.6	2.4	0.9	0.5	-1.4	2.0	1.0	-1.4	0.2
Leg fat percentage (right)	1.0	3.8	13.3	-3.4	1.8	0.7	1.7	1.4	3.6	1.4	1.5	0.7	1.8	0.2
Exposure to tobacco smoke outside home	1.0	1.3	2.6	-0.1	1.4	0.6	1.5	1.4	1.1	1.1	1.6	0.7	0.9	1.4
Leg fat mass (right)	1.0	3.8	13.9	-3.4	1.5	0.0	2.1	1.1	3.7	1.1	1.7	1.2	1.7	0.1
Handedness (chirality/laterality): Left-handed	1.0	1.2	4.2	-0.2	-0.9	-0.7	-1.9	-0.9	-2.0	0.3	-0.3	-1.1	0.7	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.2	8.2	0.1	1.5	1.5	1.6	1.8	2.9	0.2	0.5	1.1	-0.2	1.9
Number of self-reported non-cancer illnesses	1.0	1.7	3.7	-1.9	-0.3	-1.0	-1.3	-0.5	-0.8	1.7	-1.0	-1.8	1.4	-1.5
Ever depressed for a whole week	1.0	1.3	3.2	-0.6	-1.6	-1.4	-0.8	-1.2	-0.4	1.2	-1.3	-0.8	0.4	-1.8
Heart disease (siblings)	1.0	1.3	4.0	-1.2	0.3	-0.2	-1.1	0.4	-0.9	1.5	-1.4	-2.0	1.5	-0.2
Leg fat mass (left)	1.0	3.9	14.5	-3.1	1.5	0.1	2.3	1.2	3.8	1.0	2.0	1.3	1.6	0.2
Maternal smoking around birth	0.9	1.2	4.2	-1.6	0.6	0.6	0.6	1.1	2.1	1.3	0.3	-0.9	1.2	0.7
Fed-up feelings	0.9	1.7	5.1	0.6	0.4	0.5	2.3	1.0	2.0	-1.1	1.7	1.5	-1.2	0.6
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	2.5	0.7	0.3	0.9	0.8	0.3	1.2	-1.6	1.0	1.5	-1.1	0.5
Financial difficulties in last 2 years	0.9	1.3	3.3	0.0	1.0	0.6	1.8	1.0	1.2	-1.1	1.4	1.1	-0.5	1.5
Worrier / anxious feelings	0.9	1.8	5.0	1.2	0.7	0.6	0.7	1.0	1.7	-1.8	1.0	2.2	-1.4	1.1
Number of live births	0.9	1.3	6.4	-2.5	-0.8	-1.3	0.2	-0.7	-0.3	1.4	-0.5	-1.0	1.4	-0.6
Depression (self-reported)	0.9	1.0	2.3	1.5	0.8	0.9	1.3	0.8	0.9	-1.4	0.0	1.3	-0.9	0.3
Exposure to tobacco smoke at home	0.9	1.0	4.8	1.2	0.8	0.8	0.8	0.6	0.6	-1.1	2.2	-0.1	-1.0	-0.3
Headache pain in last month	0.9	1.5	3.4	-0.3	1.1	0.3	1.2	1.5	0.8	1.6	-1.2	-0.9	1.7	1.8
Migraine (self-reported)	0.9	1.1	4.7	0.2	-0.5	-0.3	-0.9	-0.5	-1.9	1.0	-2.2	-0.6	0.7	-0.1
Ever taken oral contraceptive pill	0.9	1.0	3.0	-0.4	0.4	0.9	1.3	0.4	1.6	-0.1	1.7	1.4	-0.0	0.2
Unable to work because of sickness or disability	0.9	1.1	3.3	0.5	-0.8	-1.3	1.2	-1.0	-0.1	-1.8	0.7	1.3	-1.3	-0.6
Neuroticism (Nagel 2018)	0.8	1.8	3.8	2.0	0.7	0.8	1.7	1.3	1.9	-1.4	1.2	0.6	-1.3	0.9
Schizophrenia (2018)	0.8	1.6	3.4	-1.8	1.6	1.7	1.0	1.5	1.6	0.7	-0.8	-0.1	0.7	1.2
Body Mass Index (BMI) (2010)	0.8	1.1	3.5	-1.3	-1.3	-1.9	-0.6	-1.2	-0.7	0.9	0.5	0.5	0.9	-0.8
Schizophrenia (2014)	0.8	1.9	3.5	0.4	1.8	1.8	1.5	1.8	1.9	-0.8	0.3	1.1	-0.5	1.6
Lung FEV1/FVC ratio	0.8	4.0	13.0	0.5	2.4	3.6	2.3	2.4	2.8	-0.6	1.4	0.8	0.1	1.8
Chronotype (morning person)	0.8	1.8	6.1	1.4	2.0	2.5	0.7	1.4	-0.3	-0.5	1.8	-1.0	-0.5	0.9
Time employed in main current job	0.8	0.9	2.5	-1.0	0.7	1.1	0.0	1.3	1.6	0.1	0.3	1.2	0.4	1.2
Mouth/teeth dental problems: Dentures	0.8	1.4	4.5	0.9	2.1	1.4	0.5	1.5	0.3	-0.5	1.9	-1.0	-0.7	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.1	3.3	0.4	1.2	0.9	1.1	1.4	1.1	0.9	0.8	0.5	0.5	1.8
Impedance of arm (left)	0.8	3.8	15.0	2.4	-1.7	-0.7	-2.0	-1.9	-3.9	-1.4	-0.8	-1.2	-1.8	-1.8
Length of working week for main job	0.8	0.9	2.7	-0.5	1.0	0.6	0.1	0.9	0.8	1.6	1.1	-0.5	1.4	0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	2.8	1.4	-0.0	-0.1	0.1	-0.4	1.1	-1.5	1.7	0.8	-1.2	-0.6
Heart disease (mother)	0.8	1.0	2.7	-1.5	-0.3	0.2	-0.6	0.1	-1.1	1.6	-0.6	-1.3	1.5	-0.4
Asthma (self-reported)	0.8	1.6	3.7	-1.8	-0.2	-1.0	-1.8	-0.5	-0.7	1.6	-0.9	-1.9	1.5	-0.4
Guilty feelings	0.8	1.2	2.7	-1.0	-1.7	-1.7	-1.1	-1.0	-0.3	0.2	-1.2	-1.2	0.5	-1.3
Tinnitus: Yes, now most or all of the time	0.8	0.9	3.2	1.2	0.1	0.0	0.3	-0.2	-0.2	-1.4	1.6	0.6	-1.8	-0.4
Medication: Atorvastatin	0.8	1.0	3.5	-1.5	-0.5	-0.0	-0.5	-0.6	-0.6	1.2	-0.3	-1.9	1.1	-0.9
Irritability	0.8	1.4	5.1	-1.2	0.8	1.3	1.5	1.5	2.3	0.3	-0.1	1.1	0.4	0.8
Ever had prostate specific antigen (PSA) test	0.8	0.9	4.1	0.6	0.8	0.4	0.5	0.8	0.4	-1.2	0.9	2.0	-0.9	0.5
Commuting to job workplace: Cycle	0.8	1.0	6.2	-1.0	-0.8	-0.8	-0.2	-0.3	-0.8	1.1	-0.3	-2.5	0.2	-0.5
Allergy or Eczema	0.7	1.8	6.0	-0.5	1.8	1.0	2.2	1.5	2.4	0.0	1.1	0.4	0.4	1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	4.5	-0.8	1.2	2.1	1.7	1.6	2.0	0.7	0.3	-0.2	0.8	1.3
Chronic bronchitis/emphysema (father)	0.7	0.8	2.0	0.9	1.4	0.4	0.7	1.3	0.4	0.3	1.4	-0.7	-0.4	0.9
Waist circumference	0.7	2.5	11.4	-2.4	1.0	0.1	1.7	0.6	3.4	0.7	1.7	1.3	1.1	-0.1
Qualifications: None of the above	0.7	1.5	5.5	-0.5	-0.9	-0.8	-1.3	-0.5	-1.3	1.4	-1.6	-2.4	0.7	-0.9
Noisy workplace	0.7	0.8	4.1	2.0	-0.4	-0.4	0.4	-0.1	-0.8	-1.2	-0.0	0.6	-1.2	0.6
Medication: Cholesterol lowering	0.7	1.1	2.9	-0.7	-0.7	-0.2	-1.4	-1.1	-1.2	0.6	-0.7	-1.7	0.6	-1.5
Ever highly irritable/argumentative for 2 days	0.7	0.8	1.7	0.2	-1.3	-1.3	1.0	-1.0	1.0	-0.6	0.0	1.2	-0.9	-0.5
Medication: Amlodipine	0.7	1.0	2.8	-0.2	1.1	0.9	1.4	1.6	1.0	0.2	-0.4	-0.7	0.5	1.7
Arm fat-free mass (right)	0.7	3.6	13.4	-1.2	1.1	-0.2	3.0	1.2	3.7	0.3	1.9	2.5	0.5	1.8
Medication: Ibuprofen	0.7	0.8	2.7	0.4	0.7	0.6	1.1	0.9	1.2	0.5	0.8	0.9	0.4	1.6
Alcohol intake frequency.	0.7	1.6	5.1	0.0	-2.2	-2.1	-0.5	-2.1	-0.6	-0.5	-0.3	-0.1	-0.7	-1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	3.7	1.4	-1.2	-1.3	0.9	-1.1	-0.9	-1.9	0.8	1.0	-1.8	-0.5
Loneliness, isolation	0.7	1.0	4.3	2.1	-0.7	-0.5	0.9	-0.0	-0.1	-0.8	1.0	1.1	-1.4	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	1.5	0.9	1.0	1.0	1.0	1.2	-0.7	-0.1	0.2	-1.2	-0.0	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.9	2.0	-0.6	1.3	1.4	1.4	1.2	0.6	-0.2	0.6	-0.3	-0.2	1.0
Average weekly champagne plus white wine intake	0.7	1.0	2.9	0.2	1.0	1.1	0.4	1.0	-0.2	0.9	-0.5	-1.2	1.3	1.7
Myopia	0.7	1.1	3.0	1.3	1.3	1.0	-0.4	1.5	-0.2	0.0	-0.3	-1.1	0.6	1.7
Pain experienced in last month	0.7	1.1	5.4	0.5	-0.2	-0.0	0.6	-0.3	-0.1	-1.6	0.7	1.5	-2.3	-1.0
Irritable Bowel Disease (IBD)	0.6	1.5	6.7	1.3	0.2	-0.2	0.9	0.8	1.6	-0.5	2.6	1.3	-1.0	1.3
Crohns Disease (2012)	0.6	0.9	5.7	-0.3	0.4	-0.2	1.2	0.5	2.4	0.5	1.1	0.7	-0.1	0.4
Mean Putamen Volume	0.6	0.7	4.0	-0.5	-0.4	-0.2	-2.0	-0.8	-1.0	0.5	-0.3	0.5	0.5	-0.9
Triglycerides	0.6	1.0	2.7	-0.7	1.1	1.0	0.8	1.0	1.0	-0.6	-0.4	0.2	1.3	1.6
Cardiovascular Disease	0.6	1.9	6.9	-2.6	-1.2	-1.0	-0.8	-0.8	0.2	1.9	-1.2	-1.2	1.9	-0.5
Ever had hysterectomy (womb removed)	0.6	0.7	2.1	1.5	0.7	0.4	-0.1	0.5	0.7	-1.0	1.0	1.0	-1.0	0.6
Had other major operations	0.6	0.7	2.3	0.6	1.1	1.3	-0.4	1.0	0.0	0.2	1.5	0.3	0.6	0.7
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	2.0	1.0	-1.1	-0.8	0.1	-0.9	0.1	-0.8	0.5	-0.1	-1.4	-1.4
Mouth/teeth dental problems	0.6	0.9	4.2	-0.6	-1.2	-1.1	-0.9	-1.1	-0.7	0.7	-2.0	-0.0	0.5	0.0
Weight	0.6	2.8	9.7	-1.6	0.7	-0.7	2.4	0.5	3.1	0.0	2.5	2.2	0.4	0.2
Hip circumference	0.6	2.5	11.3	-1.9	1.1	-0.2	1.8	0.8	3.4	0.5	1.7	1.9	0.8	0.1
Alcohol intake versus 10 years previously	0.6	0.8	2.7	0.6	-1.0	-0.9	-0.8	-0.6	-0.5	-0.9	0.2	1.6	-1.2	-0.7
Arm fat mass (right)	0.6	2.3	7.6	-2.5	0.7	-0.7	1.6	0.1	2.8	0.7	2.0	1.1	1.1	-0.9
Wheeze or whistling in the chest in last year	0.6	1.0	3.6	-0.5	1.1	0.5	1.1	1.2	0.7	0.4	1.5	-1.9	0.2	0.3
Age at first live birth	0.6	1.1	3.0	-0.3	0.4	1.1	0.9	1.0	1.2	-0.2	0.9	1.7	0.1	1.7
Angina (self-reported)	0.6	0.8	2.9	0.4	-1.0	-0.5	-0.9	-1.3	-0.8	-0.6	0.1	0.6	-0.3	-1.7
Arm predicted mass (right)	0.6	3.0	10.6	-1.2	1.0	-0.3	2.8	1.1	3.3	0.4	2.0	2.1	0.5	1.5
Leg pain on walking	0.6	0.7	2.2	1.5	0.9	-0.0	0.9	0.8	0.6	-1.0	0.6	0.9	-0.3	0.9
Illnesses of father: Heart disease	0.6	0.8	4.9	0.5	1.0	1.2	0.8	0.8	0.2	-0.4	2.2	-0.1	0.1	0.3
Mood swings	0.6	1.0	3.0	0.9	0.7	0.9	1.7	1.5	1.1	-0.7	0.3	0.7	-0.4	1.3
Ever had bowel cancer screening	0.6	0.7	2.6	-0.7	0.9	0.6	-0.6	0.8	-0.1	0.9	0.5	-1.6	1.1	-0.0
Eye problems/disorders: Cataract	0.6	0.6	4.3	0.4	0.6	2.1	0.1	0.2	0.5	-0.4	1.4	0.3	0.2	0.0
Back pain experienced in last month	0.6	0.9	1.8	-0.6	-1.0	-1.1	-0.4	-1.2	-0.7	0.9	-1.3	-0.8	1.1	-0.9
Breast cancer (self-reported)	0.6	0.7	4.1	-0.4	-0.2	0.4	-2.0	0.1	-0.9	1.1	1.0	-0.6	0.5	0.3
Medication: Gliclazide	0.6	0.7	2.5	-1.1	0.3	-1.1	-0.2	-0.0	-0.2	1.1	-0.8	-0.9	1.6	-0.1
Arm fat mass (left)	0.6	2.4	8.3	-2.5	0.7	-0.5	1.6	0.2	2.9	0.8	1.9	1.3	1.1	-0.7
Arm fat-free mass (left)	0.6	2.9	10.3	-1.3	0.8	-0.4	2.7	0.8	3.2	0.4	2.0	2.2	0.5	1.3
Impedance of whole body	0.6	2.8	11.2	2.5	-1.4	-0.3	-1.4	-1.2	-3.3	-1.3	-0.8	-0.9	-2.0	-1.0
Arm predicted mass (left)	0.6	3.1	11.8	-1.3	0.7	-0.4	2.7	0.8	3.4	0.4	2.0	2.5	0.5	1.4
Intelligence (Savage-Jansen 2018)	0.5	1.4	3.8	-2.0	0.5	0.5	-0.8	0.4	0.0	1.9	-1.6	-0.9	1.9	0.1
Major Depression (MDD)	0.5	0.6	2.0	0.0	-0.8	-1.2	-0.9	-0.8	0.0	-0.4	-0.7	0.2	-0.2	-1.4
Blood Eosinophil Count	0.5	4.1	17.4	-4.2	0.2	-0.1	0.2	0.4	1.4	2.3	-2.1	-3.1	2.4	0.1
Systolic blood pressure, automated reading	0.5	1.5	4.7	-2.2	0.9	0.9	-0.1	1.2	1.5	1.8	0.4	-0.1	1.6	0.7
Vitamin and mineral supplements	0.5	0.7	2.2	-1.5	-0.4	-0.5	0.9	-0.1	1.1	1.1	-0.8	0.1	0.9	-0.5
Age when periods started (menarche)	0.5	1.2	4.8	-0.5	-0.9	0.1	-1.8	-0.2	-1.4	1.0	-0.5	-2.2	0.9	-0.2
Serious illness, injury or assault to yourself	0.5	0.6	1.2	-1.1	0.9	0.6	0.5	1.0	0.9	0.3	0.8	0.0	0.9	0.4
Supplements: Glucosamine	0.5	0.7	1.7	1.3	0.3	-0.3	0.4	-0.1	-0.6	-1.2	1.3	1.3	-0.6	-0.2
Number of incorrect matches in round	0.5	0.8	2.3	0.9	1.2	1.5	0.0	1.2	0.4	-0.6	0.3	0.0	-0.7	1.0
Nervous feelings	0.5	1.0	3.8	1.9	-0.8	-0.7	-1.1	-0.6	-0.5	-1.2	-0.1	-0.7	-1.3	-0.7
Arm fat percentage (right)	0.5	2.1	8.6	-2.9	0.4	-0.7	0.7	-0.2	2.3	1.0	1.4	0.5	1.3	-1.6
Qualifications: A levels/AS levels or equivalent	0.5	1.1	4.4	-0.9	0.9	0.5	1.4	1.2	0.5	-0.4	0.4	1.4	0.1	2.1
Breastfed as a baby	0.5	0.6	1.2	0.6	0.9	0.3	0.4	1.1	0.1	-1.0	0.9	0.5	-0.8	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	1.9	1.0	-0.5	-1.0	-0.6	-0.8	-0.1	-1.1	0.2	0.5	-1.4	-1.2
Hair/balding pattern: Pattern 4	0.5	1.2	3.2	-1.4	0.1	0.6	-1.4	0.1	-1.2	1.8	-0.6	-1.0	1.6	0.2
Peak expiratory flow (PEF)	0.5	1.1	3.3	0.8	0.2	1.1	1.8	0.5	1.3	0.2	1.5	1.1	-0.1	1.1
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	3.2	0.9	0.1	-0.5	0.5	0.4	1.0	-0.8	0.9	1.8	-0.9	0.5
Body fat percentage	0.5	2.1	7.8	-2.8	0.8	-0.1	1.3	0.3	2.6	0.8	1.6	0.7	1.2	-0.9
Number of full brothers	0.5	0.6	1.9	0.8	1.0	0.3	1.1	0.7	0.9	0.1	1.4	-0.2	-0.2	0.4
Shortness of breath walking on level ground	0.5	0.6	1.5	-0.0	0.9	0.2	1.2	1.0	1.1	-1.2	-0.2	0.9	-0.6	0.3
Whole body fat mass	0.5	2.1	7.2	-2.3	0.7	-0.5	1.5	0.3	2.7	0.6	2.0	1.1	1.1	-0.6
Hypertension (Self-reported)	0.5	1.3	5.6	-2.4	-0.2	-0.8	-0.4	-0.3	-0.0	1.4	-1.4	-1.5	1.2	-0.1
Arm fat percentage (left)	0.5	2.1	7.5	-2.7	0.7	-0.4	1.0	0.1	2.6	0.9	1.7	0.7	1.2	-1.4
Medication for cholesterol	0.5	0.8	1.8	1.3	1.2	0.9	1.1	1.1	0.1	-0.6	0.9	0.4	-1.2	0.3
Wears glasses or contact lenses	0.5	0.5	1.2	1.0	0.7	-0.4	-1.0	0.3	-0.4	-0.4	1.1	0.3	-0.9	-0.8
Illnesses of father: High blood pressure	0.5	0.6	2.2	0.7	-0.3	0.2	0.9	-0.8	-0.7	-0.5	0.2	-1.5	-0.8	-0.8
Alcohol drinker status: Never	0.5	0.7	2.4	1.1	-0.1	0.1	-0.3	-0.8	-0.4	-1.6	0.3	0.5	-0.9	-1.2
Vascular/heart problems diagnosed by doctor	0.5	1.3	3.2	1.8	0.8	1.0	0.8	0.7	0.2	-1.5	1.4	1.8	-1.1	0.4
Basal cell carcinoma (self-reported)	0.5	0.6	2.4	-0.1	0.1	0.4	-0.2	0.4	1.1	1.2	-0.8	-0.1	1.5	0.7
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.4	-0.3	1.2	0.3	0.1	0.9	0.6	0.8	-1.0	1.1	1.0	0.4
Bipolar Disorder (2018)	0.4	0.7	2.1	1.4	-0.6	-0.2	-0.5	-0.9	-0.2	-0.8	0.6	0.8	-1.2	-1.0
Crohns Disease (2017)	0.4	0.9	5.9	-0.4	0.1	-0.9	0.1	0.5	2.4	0.9	1.1	0.9	0.0	0.5
Age at First Birth	0.4	0.6	3.1	0.1	-0.4	-0.7	0.6	-0.3	-0.2	-0.7	-0.4	1.8	-1.1	-0.1
Primary Biliary Cirrhosis	0.4	0.5	1.6	1.3	0.5	0.5	-0.9	0.6	-0.2	-0.3	1.1	-0.7	-0.3	0.8
Type 2 Diabetes (T2D) (2012)	0.4	0.4	2.2	-0.6	0.6	0.2	0.6	0.6	1.5	-0.1	-0.2	0.4	0.3	0.6
Blood Red Count	0.4	4.2	17.5	-0.7	-2.1	-1.9	1.0	-1.7	1.8	-2.1	0.4	4.2	-2.6	-1.5
Height	0.4	8.1	15.5	3.4	-2.9	-2.6	-0.4	-2.6	-3.1	-3.8	3.1	2.4	-3.9	-1.1
Supplements: Zinc	0.4	0.4	0.9	0.8	0.7	0.6	-0.9	0.1	-0.8	-0.2	0.8	-0.7	-0.3	-0.5
Leg fat-free mass (left)	0.4	2.0	6.8	-1.4	0.4	-1.0	2.0	0.1	2.6	0.2	2.0	1.8	0.6	0.2
Trunk fat percentage	0.4	1.6	5.0	-2.2	0.5	-0.3	1.1	0.0	2.0	0.6	1.9	0.7	0.8	-1.3
Tinnitus: Yes, but not now, but have in the past	0.4	0.5	2.5	-0.4	-0.0	-0.6	1.6	0.1	1.1	-0.7	-0.1	0.1	-0.6	0.3
Sitting height	0.4	2.5	7.1	1.7	0.5	0.1	2.4	0.6	1.0	-1.6	2.7	1.8	-1.0	1.9
Leg predicted mass (left)	0.4	2.0	7.0	-1.6	0.4	-1.0	1.9	0.1	2.6	0.3	1.9	1.8	0.7	0.2
Trunk fat mass	0.4	1.9	5.9	-2.1	0.5	-0.6	1.5	0.0	2.4	0.4	2.2	1.2	0.7	-0.9
Had menopause	0.4	0.4	1.5	-0.5	1.2	0.9	0.5	1.1	0.2	0.2	-0.6	-0.3	0.1	0.7
Trunk fat-free mass	0.4	2.2	6.7	-0.2	0.2	-0.9	2.4	0.3	2.5	-0.3	1.9	2.6	-0.2	1.2
Hair/balding pattern: Pattern 3	0.4	0.6	1.4	0.5	-1.0	-1.2	-0.3	-1.1	-0.8	-0.4	-0.4	0.7	-0.3	-0.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	4.2	0.5	-0.3	0.2	1.9	0.0	2.0	0.2	0.7	2.0	-0.2	1.5
Happiness	0.4	0.5	3.6	0.5	-0.5	-0.4	-0.2	-0.1	-0.8	0.1	-1.9	-0.3	-0.2	0.0
Trunk predicted mass	0.4	2.2	6.4	-0.1	0.3	-0.9	2.4	0.3	2.5	-0.3	1.9	2.5	-0.1	1.2
Standing height	0.4	4.5	10.4	3.2	-2.1	-2.5	1.1	-1.7	-1.6	-2.6	1.3	2.3	-2.8	0.2
Loud music exposure frequency	0.4	0.4	1.1	-0.9	-1.1	-0.8	0.5	-0.8	0.2	0.1	-0.6	-0.8	-0.1	-0.5
Blood clot in the leg (DVT)	0.4	0.5	1.4	-0.0	1.2	0.2	0.1	0.9	0.5	0.7	-0.6	1.1	0.8	0.3
Medication: Ventolin 100micrograms inhaler	0.4	0.6	2.7	0.5	-0.5	-1.1	-0.1	-0.4	0.1	-0.9	1.6	0.5	-0.6	-0.3
Worry too long after embarrassment	0.4	0.6	2.4	0.4	-1.5	-1.6	-0.1	-0.6	0.1	-0.7	0.4	-0.0	-0.7	-0.7
Medication: Seretide 50 evohaler	0.4	0.5	1.5	0.4	-0.4	-0.7	-0.8	-0.5	-1.2	0.9	-0.8	-0.0	0.8	-0.1
Comparative height size at age 10	0.4	2.4	8.4	2.9	-0.1	-0.1	2.5	-0.1	-0.7	-1.8	1.0	0.6	-2.4	0.8
Family relationship satisfaction	0.4	0.5	2.3	1.5	-0.1	0.1	-0.2	-0.2	-0.6	-0.6	-0.2	1.1	-1.0	-0.4
Whole body fat-free mass	0.4	2.4	8.0	-0.9	0.5	-0.8	2.4	0.3	2.8	-0.0	2.0	2.4	0.3	0.9
Leg fat-free mass (right)	0.4	2.0	6.9	-1.3	0.4	-1.0	2.0	0.1	2.6	0.1	2.0	2.0	0.5	0.2
Whole body water mass	0.4	2.4	8.1	-0.8	0.5	-0.8	2.4	0.4	2.9	-0.1	2.0	2.4	0.2	1.0
Leg predicted mass (right)	0.4	2.2	7.6	-1.3	0.5	-0.8	2.2	0.2	2.8	0.0	2.1	2.1	0.5	0.3
Medication: Bendroflumethiazide	0.4	0.6	2.1	-0.5	-0.2	-0.5	-1.1	-0.1	-0.3	1.3	-0.5	-1.4	1.0	-0.1
Medication: Lisinopril	0.4	0.6	2.6	0.5	0.6	0.9	1.2	0.6	1.6	-0.3	0.6	-0.3	-0.1	0.2
Basal metabolic rate	0.4	2.3	7.7	-1.1	0.3	-1.0	2.3	0.1	2.8	0.0	2.0	2.3	0.4	0.6
Cholesterol lowering medication	0.4	0.5	2.3	-1.0	0.2	0.3	0.3	0.7	1.5	-0.0	0.2	0.4	0.9	1.0
Coronary Artery Disease (CAD)	0.3	0.3	0.9	0.8	-0.7	-0.4	-0.3	-0.2	-0.2	-0.7	0.2	0.9	-0.2	0.8
HDL Cholesterol	0.3	0.6	1.3	0.2	-1.0	-0.8	-0.7	-0.8	0.3	-0.4	0.9	-0.2	-1.0	-1.1
Heel T-Score	0.3	2.8	11.2	-1.7	1.1	1.6	1.7	1.4	3.4	0.1	-0.6	2.0	0.5	1.7
Respiratory disease	0.3	0.6	2.2	-0.5	-0.1	-0.6	-1.5	-0.3	-0.4	0.9	1.0	-1.1	0.7	-0.2
Neuroticism	0.3	0.7	1.9	0.8	0.2	0.9	0.7	1.0	1.4	-0.9	1.3	0.3	-0.7	0.1
Angina	0.3	0.4	1.9	0.5	-0.6	-0.2	-0.6	-0.9	-0.4	-0.5	0.4	0.5	-0.3	-1.4
Pack years adult smoking proportion	0.3	0.5	1.9	-0.8	-0.5	-0.3	-1.4	-0.3	0.6	0.9	-0.9	-0.0	0.2	-0.2
Impedance of leg (right)	0.3	1.7	6.8	1.9	-1.2	-0.1	-1.1	-0.8	-2.6	-0.9	-1.1	-0.8	-1.5	-0.2
Hand grip strength (right)	0.3	0.8	5.0	0.4	0.0	-0.1	1.1	-0.1	1.0	-0.6	0.7	2.2	-0.8	0.4
Townsend deprivation index at recruitment	0.3	0.4	1.4	-0.4	-0.8	-0.1	-0.1	-0.6	-0.4	0.5	-0.3	-1.2	0.3	-0.8
High blood pressure	0.3	0.9	2.7	-1.6	-0.4	-0.8	-0.5	-0.3	-0.3	1.1	-1.1	-1.5	0.8	-0.2
Impedance of leg (left)	0.3	1.6	5.9	1.9	-1.1	0.1	-0.6	-0.7	-2.4	-1.2	-0.9	-0.6	-1.7	-0.2
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.4	-1.2	-0.3	-0.6	-0.5	-0.5	-0.6	-0.2	-1.0	-0.6	-0.1	-0.7
Qualifications: College or University degree	0.3	1.0	3.7	0.3	0.3	0.4	1.0	0.9	0.2	-0.5	1.4	1.9	-0.2	1.5
Medication for pain relief, constipation, heartburn	0.3	0.5	1.6	1.0	-0.4	0.0	0.2	-0.5	-0.5	-1.3	-0.4	0.7	-1.1	0.0
Medication: Blood pressure	0.3	0.5	2.9	-0.5	0.0	0.2	0.0	-0.0	-0.4	0.7	-0.9	-1.7	0.8	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.3	-0.9	-0.5	-0.2	-1.2	-0.4	0.4	0.6	-0.5	-0.3	0.6	0.0
Supplements: Vitamin C	0.3	0.4	3.2	-0.7	-0.2	-0.4	-1.8	-0.4	-0.0	0.2	0.5	-0.2	0.0	-0.0
Knee pain experienced in last month	0.3	0.5	1.3	0.3	0.5	-0.2	0.4	0.5	-0.0	1.2	1.1	-0.7	1.1	0.7
Long-standing illness, disability or infirmity	0.3	0.5	1.3	-0.2	1.1	0.3	-0.2	0.8	0.2	0.7	0.8	-1.1	0.8	0.6
Medication: Aspirin	0.3	0.4	1.5	-0.0	0.9	1.0	0.5	0.8	0.3	0.1	1.2	-0.2	0.0	-0.1
Mother’s age at death	0.3	0.3	0.7	0.4	0.2	-0.4	-0.9	0.2	0.6	-0.9	0.7	0.4	-0.8	-0.2
Commuting to job workplace: Public transport	0.3	0.3	1.1	0.9	-0.1	-0.1	-0.5	-0.1	-1.0	0.2	0.9	-0.3	-0.2	-0.6
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.1	0.6	0.1	-0.8	-0.1	-0.3	-0.1	-0.9	0.8	1.0	-0.1	-0.2
High cholesterol (Self-reported)	0.3	0.5	1.9	-1.4	-0.6	-0.2	-0.9	-0.2	0.4	0.6	-0.4	-0.5	1.2	-0.3
Medication: Paracetamol	0.3	0.5	1.9	-0.0	0.4	0.2	0.7	0.5	1.2	-0.3	1.4	0.9	0.1	0.0
Diastolic blood pressure, automated reading	0.3	0.8	2.7	-1.4	0.4	-0.0	-0.4	0.5	1.6	0.5	1.6	0.2	0.6	0.0
Pack years of smoking	0.3	0.4	1.9	-0.5	-0.5	-0.3	-1.4	-0.4	0.4	0.5	-0.7	0.4	-0.1	-0.5
Bipolar Disorder or Schizophrenia	0.2	0.4	1.3	-0.5	0.9	1.1	0.5	0.6	1.1	0.1	-0.3	0.4	-0.2	0.4
LDL Cholesterol	0.2	0.3	1.1	0.7	-0.3	0.1	-0.1	0.2	0.7	-1.0	0.9	-0.4	-0.0	0.7
Systolic Blood Pressure	0.2	1.1	3.1	-1.6	-1.8	-1.3	-0.5	-1.1	-0.1	1.0	-1.2	0.1	0.1	-0.6
Lung FVC	0.2	1.1	3.3	-1.5	-0.1	-0.4	-0.4	-0.3	1.1	1.8	-1.3	-0.8	1.4	-0.7
Hand grip strength (left)	0.2	0.6	1.4	-0.5	-1.2	-1.1	-1.0	-0.9	-0.7	0.7	-0.3	0.8	0.3	-0.5
Relative age of first facial hair	0.2	0.5	2.1	-1.5	-0.7	-0.3	-1.0	-0.3	-0.0	0.4	-1.2	-0.1	0.5	0.0
Diabetes (mother)	0.2	0.2	0.8	0.3	-0.5	-0.3	-0.8	-0.2	-0.9	0.1	-0.1	-0.3	0.1	-0.5
Severe depression (siblings)	0.2	0.3	1.3	0.6	0.4	0.6	0.3	0.3	1.1	-0.4	0.3	0.3	-0.2	0.1
Stomach or abdominal pain in last month	0.2	0.2	0.8	-0.9	-0.1	-0.1	0.2	0.0	0.7	-0.2	-0.0	-0.3	0.5	-0.8
Forced vital capacity (FVC)	0.2	0.7	1.8	0.5	-0.7	-0.7	1.3	-0.3	1.2	0.2	0.2	1.4	-0.2	1.3
Allergy	0.2	0.4	2.2	-0.1	-1.5	-0.2	-0.7	-0.8	-0.6	0.2	-0.7	-0.3	0.0	0.2
Neuroticism score	0.2	0.3	2.1	-0.1	-0.3	0.1	0.5	0.7	1.5	-0.5	0.5	0.2	-0.5	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.7	0.1	0.5	0.4	0.5	0.4	0.6	-0.7	0.7	0.8	-0.5	0.1
Medication: Lansoprazole	0.2	0.2	0.8	-0.4	-0.3	-0.2	-0.9	-0.4	-0.4	0.5	-0.8	-0.0	0.4	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	3.1	-0.1	-1.0	-0.5	1.1	-0.6	0.9	-0.2	-0.1	1.8	-0.7	0.5
Pulse wave Arterial Stiffness index	0.2	0.2	0.6	-0.4	-0.4	-0.2	-0.6	-0.6	-0.5	-0.2	-0.4	0.3	-0.2	-0.7
Qualifications: O levels/GCSEs or equivalent	0.2	0.4	1.8	-1.2	0.1	-0.5	0.2	-0.2	0.6	0.0	-0.3	1.3	0.2	0.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	0.8	-0.3	-0.7	-0.9	-0.0	-0.5	-0.5	0.2	-0.3	-0.2	0.2	-0.5
Medication: Paracetamol	0.2	0.3	1.2	-0.9	-0.0	-0.2	0.1	0.2	1.1	0.6	0.7	0.2	0.7	-0.2
Emphysema/chronic bronchitis	0.2	0.2	0.9	-0.5	0.1	-0.6	-0.3	0.2	-0.4	0.6	0.9	-0.1	-0.1	-0.5
Medication: Omeprazole	0.2	0.3	1.6	-0.0	0.1	0.4	0.3	0.1	0.1	0.8	-0.6	-1.3	0.2	-0.4
Overall health rating	0.2	0.4	1.8	0.5	0.5	0.1	0.1	0.3	-0.1	-0.1	1.1	-1.4	0.5	0.2
Chest pain or discomfort	0.2	0.2	0.9	0.3	-0.4	-0.6	-0.4	-0.4	-0.3	-0.4	-0.1	1.0	-0.5	-0.3
Had major operations	0.2	0.3	0.9	0.2	0.6	0.2	-0.2	0.9	0.5	0.5	-0.2	-0.6	0.7	0.8
Medication: Aspirin	0.2	0.3	1.1	-0.3	0.6	0.6	-0.1	0.5	-0.4	0.4	1.0	-0.6	0.2	-0.5
Friendships satisfaction	0.2	0.3	1.1	0.5	-0.6	-1.0	-0.1	-0.1	-0.3	0.6	-0.1	-0.6	-0.5	-0.3
Osteoarthritis (self-reported)	0.2	0.3	1.0	-0.7	0.5	-0.1	0.6	0.1	1.0	0.5	-0.8	-0.1	0.2	-0.4
Miserableness	0.2	0.4	1.1	0.3	-0.0	-0.1	1.0	0.5	0.7	-0.6	1.0	-0.1	-0.8	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.7	-0.0	0.2	0.3	0.2	0.4	0.3	0.8	-0.8	-0.8	0.3	0.2
Waist Hip Ratio (WHR)	0.1	0.3	0.9	0.1	-0.9	0.1	0.6	-0.5	0.0	-0.5	0.4	0.3	-0.8	-0.3
Sensitivity / hurt feelings	0.1	0.2	0.4	-0.4	0.4	0.6	-0.6	0.5	0.4	0.3	-0.4	0.0	0.3	0.2
Relative age voice broke	0.1	0.1	0.7	-0.8	-0.6	0.5	0.2	0.1	0.2	0.1	0.1	-0.1	0.0	0.1
Medication: Simvastatin	0.1	0.1	0.3	-0.5	0.0	-0.1	-0.6	0.2	0.1	-0.3	-0.2	-0.3	0.4	0.2
Fluid intelligence score	0.1	0.3	0.9	-0.7	-0.3	-0.1	0.1	-0.6	0.1	0.2	0.1	0.8	0.4	-1.0
Forced vital capacity (FVC), Best measure	0.1	0.5	1.7	0.2	-0.7	-0.4	1.0	-0.2	0.6	-0.2	-0.2	1.3	-0.6	1.1
Comparative body size at age 10	0.1	0.2	0.7	0.8	0.1	-0.1	0.1	-0.4	-0.7	-0.1	0.8	-0.3	-0.1	-0.4
Pulse wave peak to peak time	0.1	0.1	0.5	0.7	-0.0	-0.1	0.5	0.3	0.2	-0.1	0.3	0.0	-0.1	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.4	-0.1	-0.2	-0.1	-0.6	-0.1	-0.2	0.5	-0.6	0.0	-0.1	-0.4
Medication: Blood pressure	0.1	0.2	0.8	-0.8	0.0	-0.3	-0.4	0.0	0.2	0.9	-0.2	-0.7	0.4	0.2
Average weekly beer plus cider intake	0.1	0.2	0.6	-0.4	0.3	0.5	0.5	0.2	0.7	-0.1	0.3	0.6	0.5	-0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.6	2.1	-0.5	-0.4	-0.2	-0.1	-0.4	0.7	1.3	-0.6	-1.5	1.2	-0.2
Tanning	0.0	0.4	1.2	-1.1	0.6	0.2	1.0	0.5	0.9	0.6	-0.4	0.4	0.3	0.3

Hub : Genes

RNF167

Models

Trait associations