TWAS hub - RNF187

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Nucleus accumbens basal ganglia	0.2390	0.0910	6.5e-03	-0.007	NA	-0.009	NA	-0.006	5.6e-01	NA	6.9e-01	NA	5.2e-01
2	GTEx	Cells Transformed fibroblasts	0.1750	0.0630	1.2e-03	0.008	NA	0.056	NA	0.051	7.9e-02	NA	4.7e-05	NA	1.1e-04
3	GTEx	Heart Atrial Appendage	0.2840	0.1020	2.1e-03	-0.003	NA	0.062	NA	-0.006	5.0e-01	NA	9.6e-04	NA	7.2e-01
4	METSIM	Adipose	0.0708	0.0260	7.8e-05	0.018	0.021	0.029	0.023	0.030	9.1e-04	3.6e-04	3.2e-05	1.8e-04	2.2e-05
5	NTR	Blood	0.0211	0.0083	6.4e-04	0.015	0.007	0.010	0.011	0.013	9.4e-06	1.3e-03	2.4e-04	1.6e-04	4.0e-05
6	YFS	Blood	0.0623	0.0164	5.6e-17	0.049	0.059	0.070	0.064	0.070	1.3e-15	1.4e-18	9.5e-22	5.1e-20	7.0e-22
7	TCGA	Kidney Renal Clear Cell Carcinoma	0.0546	0.0293	3.3e-03	0.015	0.024	0.039	NA	0.035	7.3e-03	8.2e-04	3.0e-05	NA	7.0e-05
8	TCGA	Kidney Renal Papillary Cell Carcinoma	0.2480	0.1280	6.8e-04	0.020	0.029	0.001	NA	0.026	2.5e-02	8.6e-03	2.6e-01	NA	1.2e-02
9	TCGA	Brain Lower Grade Glioma	0.0824	0.0429	6.6e-04	0.030	0.022	0.032	NA	0.027	2.2e-04	1.3e-03	1.3e-04	NA	4.6e-04
10	TCGA	Ovarian Serous Cystadenocarcinoma	0.1990	0.0620	6.4e-07	0.113	0.127	0.106	NA	0.107	5.0e-08	6.2e-09	1.3e-07	NA	1.0e-07
11	TCGA	Pancreatic Adenocarcinoma	0.2750	0.1000	1.3e-03	-0.006	0.056	0.058	NA	-0.007	8.1e-01	2.4e-03	2.0e-03	NA	8.5e-01
12	TCGA	Prostate Adenocarcinoma	0.1436	0.0456	2.2e-08	0.090	0.085	0.097	NA	0.089	1.1e-09	3.4e-09	2.7e-10	NA	1.5e-09
13	TCGA	Soft Tissue Sarcoma	0.1370	0.0620	6.1e-03	0.021	0.033	0.010	NA	0.032	2.0e-02	4.4e-03	7.9e-02	NA	5.1e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Medication: Atorvastatin	3.2	4.0	15.4	0.6	2.8	0.5	3.9	3.2	-1.1	1.4	3.3	0.0	-0.4	-0.7	-0.2	2.0
Medication: Cholesterol lowering	2.6	4.1	15.2	1.0	3.0	1.5	3.9	3.0	-0.1	1.8	2.9	-0.5	0.4	-1.2	0.3	1.8
Average weekly spirits intake	2.3	2.8	8.2	-0.9	0.5	1.6	1.3	0.3	-0.4	2.2	0.7	0.2	2.2	2.6	2.4	2.9
Had major operations	2.3	2.7	8.8	0.6	1.8	-1.9	1.8	1.0	-3.0	0.5	-0.9	-1.7	-1.7	-1.6	-2.1	-0.6
Supplements: Vitamin C	2.3	2.7	14.9	-3.9	-1.2	-1.4	-2.2	-2.4	1.6	-0.5	-0.7	0.9	0.4	1.2	0.4	-0.6
Illnesses of siblings: Diabetes	2.2	2.7	10.8	3.3	1.3	-2.3	1.1	1.2	-0.3	-0.4	-1.0	-1.6	-1.9	-1.3	-2.2	-0.6
Impedance of arm (right)	2.1	9.8	26.2	2.0	5.1	3.6	4.2	3.2	-1.3	4.6	3.4	1.1	2.9	-0.7	1.2	3.1
Pack years adult smoking proportion	2.0	3.1	7.6	-2.2	-1.9	-1.5	-0.7	0.2	-0.4	-1.8	-2.3	-1.3	-1.4	-2.4	-1.8	-2.8
Hair/balding pattern: Pattern 2	2.0	2.6	9.0	-1.2	-1.9	-0.3	-3.0	-2.3	1.3	-0.5	-1.6	1.2	1.4	2.3	0.8	-1.1
Crohns Disease (2012)	1.9	3.0	10.2	-1.1	-2.4	0.2	-3.2	-1.7	1.0	-0.5	0.6	1.9	2.0	2.1	2.3	-0.3
Happiness	1.9	2.3	6.5	0.5	0.7	-0.9	-1.9	-0.5	2.0	-1.5	-0.7	1.9	0.6	-2.2	-1.4	-2.5
Ever had bowel cancer screening	1.9	2.2	8.9	0.9	3.0	0.7	2.5	1.5	-0.8	0.8	1.1	-1.4	-1.3	-1.9	-0.5	0.6
Myopia	1.9	2.7	7.7	2.8	2.1	1.9	2.6	1.9	-0.5	0.5	1.0	-1.9	-1.4	-1.1	-0.5	0.9
Had other major operations	1.8	2.2	6.0	-0.2	2.4	2.3	1.1	2.1	1.8	0.0	2.4	1.0	-0.2	-1.0	0.5	0.2
Impedance of arm (left)	1.8	8.5	21.6	1.7	4.7	3.8	3.9	3.0	-0.9	4.2	3.1	0.9	2.7	-0.7	1.3	3.0
Medication for cholesterol, blood pressure or diabetes	1.8	3.0	14.1	-1.7	-2.0	-0.3	-3.8	-2.1	1.0	-1.5	-1.8	1.4	0.2	1.3	0.6	-1.8
Medication: Blood pressure	1.8	3.1	14.1	2.1	1.8	-0.5	3.7	1.9	-2.0	1.5	0.7	-1.5	-0.5	-1.2	-1.0	1.8
Medication: Aspirin	1.8	2.4	9.8	0.4	2.8	0.6	3.1	2.8	-0.8	1.3	0.9	0.1	0.3	-0.6	-0.1	1.4
Friendships satisfaction	1.8	2.2	7.2	-0.4	0.8	-0.7	-1.4	-0.5	2.7	-2.6	-0.1	1.8	-0.4	-2.0	-1.1	-1.6
Pack years of smoking	1.8	2.7	7.3	-1.9	-1.3	-1.3	-0.4	0.5	-0.2	-1.6	-2.0	-1.1	-1.5	-2.7	-1.9	-2.7
Number of full brothers	1.7	2.2	4.9	1.2	-2.1	-2.1	0.7	0.1	-2.2	-0.4	-1.7	-2.2	-1.7	1.0	-0.6	-0.5
Age at first live birth	1.7	3.1	9.2	0.3	0.9	2.0	3.0	2.8	-0.9	1.8	2.5	0.2	0.9	0.1	1.2	2.4
Health satisfaction	1.7	2.2	4.8	1.4	-0.5	-1.0	-2.1	-1.5	1.8	-2.0	-1.5	0.5	-0.7	-0.9	-1.7	-2.2
Basal cell carcinoma (self-reported)	1.7	2.0	17.1	4.1	0.8	-0.8	1.9	1.1	0.5	0.5	0.9	-0.6	-0.3	0.1	-0.3	0.8
Coronary Artery Disease (CAD)	1.6	2.0	4.6	1.2	2.1	1.0	0.4	-0.2	1.0	1.4	0.5	2.0	2.1	0.4	1.6	1.9
Ever had hysterectomy (womb removed)	1.6	1.8	5.2	-0.9	0.2	-1.8	-0.6	-0.1	-0.5	-1.0	-1.7	-2.0	-2.3	-0.4	-1.9	-1.6
Cholesterol lowering medication	1.6	2.4	7.6	-0.3	0.8	-0.8	1.7	2.6	-0.2	-1.1	0.7	-1.6	-2.2	-2.8	-1.1	-1.3
HDL Cholesterol	1.5	2.5	11.5	0.8	0.3	-0.9	0.2	1.1	-1.4	-1.4	-0.5	-1.7	-1.8	-3.4	-2.2	-1.8
Number of incorrect matches in round	1.5	2.5	6.7	1.7	2.3	2.6	0.9	0.3	1.6	1.8	1.8	0.6	1.0	0.7	1.3	1.9
Diabetes (self-reported)	1.5	2.3	9.6	0.0	3.1	0.6	2.4	1.7	0.1	1.2	1.8	-1.2	-1.0	-1.7	-1.2	0.7
Illnesses of mother	1.5	1.9	5.9	-0.2	-0.5	1.2	-1.3	-0.7	0.1	0.6	0.5	1.5	2.2	2.4	2.2	1.3
Medication: Amlodipine	1.5	2.1	6.7	0.3	-1.0	-1.5	2.6	1.2	-2.5	1.5	0.7	-2.4	-0.4	-0.1	0.2	1.1
Guilty feelings	1.5	2.3	5.4	1.2	-1.4	-1.1	-1.8	-0.6	0.9	-2.1	-1.5	-0.4	-1.5	-1.5	-2.1	-2.3
Supplements: Calcium	1.5	1.6	5.4	-0.9	0.0	-1.4	-1.2	-0.6	1.6	-1.1	-0.8	0.3	-0.8	-1.9	-1.4	-2.3
Medication: Metformin	1.4	2.0	5.8	-0.4	1.8	2.4	1.8	0.9	0.8	1.4	2.2	-0.6	-0.5	0.3	1.3	1.6
Relative age voice broke	1.4	2.2	9.5	1.2	2.1	-0.2	1.8	1.0	-0.0	-0.9	1.0	-0.7	-1.9	-3.1	-1.6	-0.0
Illnesses of siblings	1.4	1.9	5.4	-2.2	0.7	2.1	-0.3	-0.8	0.7	0.8	0.4	1.9	2.3	0.9	1.1	1.4
Number of live births	1.4	1.9	5.6	-0.9	-2.3	-0.9	-2.4	-2.0	0.8	-1.4	-1.3	-0.1	-0.8	0.6	-0.6	-1.7
Lung cancer (father)	1.4	1.6	7.6	-1.0	-1.1	-1.6	-1.5	-0.2	0.2	-1.1	-2.8	-0.3	-0.1	0.1	-1.6	-1.7
Medication: Aspirin	1.4	1.9	7.3	0.4	2.5	0.0	2.7	2.6	-0.2	0.6	0.7	-0.2	-0.4	-1.3	-0.6	0.9
Illnesses of father: High blood pressure	1.4	1.7	7.2	0.8	-1.6	-2.1	0.3	-1.3	-1.3	-0.7	-1.0	-0.4	-0.8	2.7	0.2	1.1
Ever had prostate specific antigen (PSA) test	1.4	1.6	4.9	-0.0	0.9	-0.7	2.2	2.2	-1.3	0.1	1.1	-1.3	-1.8	-0.3	-1.4	0.4
Alcohol drinker status: Previous	1.4	1.5	4.8	-0.8	-0.4	-0.6	0.6	-0.5	-0.9	-0.2	-2.2	-2.2	-1.9	-0.5	-1.9	-0.8
Fasting Glucose	1.3	1.6	5.5	0.8	-0.2	-0.3	-1.6	-0.5	2.3	-1.9	-1.0	0.6	-0.5	-1.0	-1.5	-1.6
Had menopause	1.3	1.6	8.1	0.8	1.3	1.1	0.7	1.6	0.2	-0.8	0.2	-1.1	-1.5	-2.9	-0.8	-1.1
Diabetes diagnosed by doctor	1.3	2.1	9.5	0.6	3.1	0.5	2.3	1.5	-0.3	1.1	1.7	-1.1	-0.9	-1.6	-1.0	0.6
Unable to work because of sickness or disability	1.3	1.7	4.5	2.0	1.9	-1.1	2.1	1.4	-0.1	1.2	1.8	-0.7	-0.8	-0.6	-0.7	0.6
Body Mass Index (BMI) (2010)	1.2	1.6	4.8	-1.5	-1.1	-2.0	-1.9	-2.0	-0.2	-0.2	-2.2	0.1	0.1	0.4	-0.3	-0.9
Sensitivity / hurt feelings	1.2	2.0	8.2	2.9	2.0	-0.3	1.4	1.5	1.1	0.4	1.2	-0.9	-1.1	-1.9	-0.6	0.7
Hearing difficulty/problems with background noise	1.2	2.0	6.2	0.7	0.3	-0.4	-0.8	0.1	0.1	-2.0	-0.7	-1.3	-2.5	-2.1	-1.6	-2.2
Pain all over the body in last month	1.2	1.3	3.5	1.4	1.8	1.6	0.7	0.8	0.5	1.2	0.3	0.5	1.9	0.6	0.5	1.6
Worrier / anxious feelings	1.2	2.2	6.7	2.2	2.6	0.4	2.1	1.5	0.2	2.0	0.8	-0.7	0.8	-1.1	-0.6	1.6
Length of working week for main job	1.2	1.3	3.7	0.2	1.4	-1.3	-0.1	1.3	0.2	-1.6	0.8	0.7	-0.4	-1.9	-1.6	-1.2
Mouth/teeth dental problems: Bleeding gums	1.2	1.5	4.1	1.9	1.2	0.4	1.9	1.0	-1.0	2.0	1.6	-0.6	0.6	0.4	0.8	1.1
High blood pressure (siblings)	1.2	1.7	7.1	1.5	-1.3	-2.7	-0.0	-0.5	-1.8	0.1	-1.1	-1.8	-1.4	0.1	-0.5	-0.9
Breast cancer (self-reported)	1.2	1.4	4.8	-0.5	-1.7	-0.8	-0.8	-2.1	-0.7	0.3	-0.2	-1.2	-0.9	2.2	1.2	0.4
Commuting to job workplace: Cycle	1.2	1.5	5.9	1.1	-1.7	-1.5	-0.1	-0.7	-2.4	-0.0	-0.7	-1.8	-1.0	1.1	0.3	-0.4
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	4.6	0.2	1.1	0.5	1.4	0.1	-0.4	2.1	1.0	0.4	0.7	1.6	1.3	2.2
Impedance of whole body	1.2	6.0	16.4	1.9	4.0	3.5	2.8	2.5	0.4	3.6	2.5	0.7	2.2	-1.4	1.1	1.8
Type 2 Diabetes (T2D) (2012)	1.1	1.3	3.5	-1.3	1.9	1.1	-0.1	0.5	0.7	0.8	1.8	1.6	1.5	-0.7	0.5	0.1
Angina	1.1	1.4	6.5	0.8	1.0	1.2	1.9	2.5	0.4	0.4	1.6	0.0	-0.3	-1.4	-0.0	0.2
Supplements: Zinc	1.1	1.2	4.2	-1.2	0.1	-2.1	-1.1	-0.5	1.0	-0.7	-1.2	0.8	-0.2	-0.6	-1.4	-1.6
Diabetes (mother)	1.1	1.4	4.3	-0.9	1.7	0.1	1.0	2.1	1.9	0.4	1.3	0.7	0.3	-1.7	-0.8	-0.2
Nervous feelings	1.1	2.1	7.7	1.6	1.4	-0.3	2.8	1.6	-0.3	2.4	0.9	-1.2	0.2	-0.3	0.7	1.8
Heart attack	1.1	1.4	7.4	1.0	0.4	1.0	2.1	2.7	-1.1	0.2	-0.4	-1.3	-0.8	-0.8	-0.4	-0.2
Noisy workplace	1.1	1.4	4.7	-0.7	-1.2	-0.9	-2.0	-2.2	1.0	-1.4	-1.1	0.7	-0.2	1.3	-0.1	-0.7
Medication: Lansoprazole	1.1	1.2	4.4	-0.6	0.6	1.4	-0.1	-0.4	0.0	1.8	1.7	0.1	1.0	0.9	2.1	1.0
Angina (self-reported)	1.1	1.4	5.7	0.6	1.1	1.2	1.9	2.4	0.6	0.2	1.6	0.2	-0.3	-1.6	-0.1	0.3
Mean time to correctly identify matches	1.1	2.0	6.9	-0.1	2.6	0.6	2.6	2.2	1.2	-0.1	0.6	-0.0	-0.5	-1.9	-1.3	0.7
Family relationship satisfaction	1.1	1.3	4.8	0.8	-0.5	-0.3	-2.2	-1.9	1.4	-0.9	-0.4	1.7	1.0	-0.3	0.2	-1.1
Number of self-reported non-cancer illnesses	1.1	1.9	6.9	0.7	2.6	0.5	1.9	1.7	0.8	1.5	1.6	1.0	0.7	-1.3	0.1	1.0
Tinnitus: Yes, now most or all of the time	1.1	1.3	5.1	0.7	-0.8	1.8	0.1	-0.5	-1.0	0.8	1.1	-0.3	0.7	1.6	2.3	0.9
Vascular/heart problems diagnosed by doctor	1.1	3.1	13.8	-1.4	-0.4	0.3	-3.7	-2.4	1.9	-2.2	0.4	2.4	0.1	-0.9	-0.7	-1.6
Heart attack/myocardial infarction (self-reported)	1.1	1.4	7.6	0.8	0.5	1.4	2.0	2.8	-0.9	0.1	-0.4	-1.1	-0.6	-1.0	-0.4	-0.1
HbA1C	1.0	1.1	4.3	0.1	-0.7	-1.6	-0.6	-1.0	-0.3	0.3	-2.1	-1.1	-0.2	2.1	-0.0	-0.3
Rheumatoid Arthritis	1.0	1.4	8.6	0.5	-0.5	0.1	0.8	0.3	-1.6	0.8	0.8	-0.2	0.1	2.9	1.4	1.6
BMI	1.0	5.7	13.7	-0.6	-3.7	-1.5	-3.4	-3.3	0.6	-3.7	-3.1	0.0	-1.6	2.0	-1.4	-1.9
Type 2 Diabetes (T2D) (2018)	1.0	2.0	6.2	1.6	2.1	0.3	2.5	1.7	-0.9	0.9	1.2	-1.7	-1.3	-0.7	-0.6	0.7
Hearing difficulty/problems: Yes	1.0	1.5	4.8	-1.0	-0.7	-0.0	-2.2	-1.3	0.8	-1.7	-0.5	-0.1	-1.5	-0.8	-0.3	-2.2
Supplements: Glucosamine	1.0	1.3	5.6	0.5	-1.2	-1.7	-1.7	-1.2	0.2	0.1	-0.7	0.6	0.4	2.4	1.0	0.4
Loud music exposure frequency	1.0	1.1	6.2	-0.8	-2.0	-2.5	-0.8	-0.1	0.9	0.1	-0.6	-0.6	-0.5	0.5	-0.2	-1.0
Worry too long after embarrassment	1.0	1.7	6.5	1.7	2.6	0.5	1.1	1.1	1.7	0.5	1.2	0.2	0.1	-1.9	-1.1	0.5
Illnesses of father: None of the above (group 1)	1.0	1.2	4.4	0.3	0.5	-0.2	-1.4	0.0	1.3	-1.3	-0.3	1.2	-0.1	-2.1	-1.2	-1.5
Neuroticism (2016)	0.9	1.2	6.5	1.6	2.5	0.2	1.1	0.3	-1.1	1.4	-0.2	0.1	0.8	0.4	0.2	1.3
Primary Biliary Cirrhosis	0.9	1.3	3.8	1.1	0.7	-0.2	0.7	0.2	0.4	0.8	1.6	1.2	1.0	1.6	1.4	2.0
Number of treatments/medications taken	0.9	1.6	6.0	1.2	1.6	-0.3	2.0	1.1	-1.0	2.5	0.7	-1.0	0.6	-0.1	0.6	1.2
Eye problems/disorders: Diabetes related eye disease	0.9	0.9	5.9	0.2	0.9	0.3	0.8	0.7	2.4	0.3	1.4	1.1	0.5	0.5	0.2	0.7
Medication for hormone replacement therapy	0.9	1.0	3.2	-0.0	1.8	0.9	-0.4	-0.3	0.3	0.8	0.8	1.7	1.7	0.3	0.9	0.7
Medication: Co-codamol	0.9	1.1	2.6	0.4	1.6	1.6	0.8	0.3	0.2	-1.3	1.3	-0.5	-1.6	-1.0	-0.9	-0.5
Average weekly fortified wine intake	0.9	1.1	2.2	0.6	1.1	1.1	0.9	0.1	0.6	1.2	1.4	0.4	0.8	1.1	1.4	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.8	0.3	1.8	0.3	0.3	-0.1	0.3	1.9	1.1	0.7	1.9	1.0	1.1	0.7
Pulse wave reflection index	0.9	1.1	7.0	0.6	-0.9	-0.4	-1.0	0.3	0.1	-1.4	-1.1	-0.1	-1.0	-0.4	-0.4	-2.6
Glaucoma (self-reported)	0.9	1.0	2.7	0.1	1.4	0.1	1.6	0.8	-1.1	0.7	1.3	-0.8	-0.3	1.3	0.4	1.4
Arm fat-free mass (right)	0.9	4.6	15.9	-1.0	-2.5	-2.6	-1.2	-1.2	1.8	-4.0	-1.4	-0.7	-2.8	-1.8	-2.2	-2.1
Medication for pain relief, constipation, heartburn	0.9	1.6	5.0	-2.2	-1.2	0.4	-1.7	-0.8	1.2	-2.2	0.3	0.5	-0.2	-0.5	-0.8	-1.6
Medication: Omeprazole	0.9	1.1	3.4	0.2	0.7	0.0	1.7	0.3	-0.9	1.7	1.1	-0.2	0.1	1.2	1.0	1.9
Hypertension (Self-reported)	0.9	2.4	10.0	1.3	0.2	-0.8	3.2	1.2	-2.0	1.7	-0.8	-2.5	-0.6	1.0	0.1	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.9	0.9	3.4	-1.0	0.4	-0.1	-1.8	-1.5	1.3	-0.3	-0.5	1.6	0.1	0.2	0.3	-0.6
Eye problems/disorders: Glaucoma	0.9	1.0	3.8	-0.0	0.8	0.2	2.0	0.9	-1.3	0.9	1.0	-0.9	-0.5	0.9	0.5	1.4
Pain type(s) experienced in last month: Hip pain	0.9	1.1	4.1	-0.8	0.7	-0.9	-0.8	-0.9	2.0	-1.6	-1.0	0.3	-0.9	-1.3	-0.7	-0.6
High cholesterol (Self-reported)	0.9	1.7	7.6	0.4	1.4	-0.5	2.8	2.1	-0.7	0.3	1.1	-1.0	-0.9	-1.9	-0.4	0.4
Medication: Lisinopril	0.9	1.2	3.0	0.8	0.5	-1.1	1.6	0.2	-1.3	-0.7	-0.8	-1.2	-1.4	-1.7	-1.4	-0.3
Risk taking	0.9	1.3	6.2	-2.5	-1.2	-0.2	-1.7	-1.2	-0.2	-0.0	-1.1	0.3	0.6	1.5	0.1	-0.7
Age at First Birth	0.8	1.1	3.9	1.5	0.7	1.4	1.1	1.1	1.3	-0.1	2.0	1.1	0.1	-0.2	0.1	0.7
Hypothyroidism (self reported)	0.8	1.8	7.6	-0.5	-2.8	-0.7	-1.4	-1.9	0.7	-1.5	-1.8	-0.8	-1.1	-0.6	-0.9	-0.9
Tinnitus: Yes, but not now, but have in the past	0.8	0.8	2.9	1.7	0.8	-1.0	0.1	-0.1	-0.7	0.0	-1.5	-0.3	-0.9	-0.7	-1.6	0.3
High blood pressure	0.8	2.3	9.5	1.4	0.1	-0.8	3.1	1.6	-1.9	1.7	-0.8	-2.5	-0.4	0.8	0.2	1.2
Medication: Simvastatin	0.8	1.2	4.1	-0.2	0.9	0.7	2.0	1.6	-0.1	-0.3	1.3	-1.1	-0.9	-1.8	0.3	-0.2
Number of children fathered	0.8	0.9	6.0	0.6	2.4	1.0	-0.4	-0.3	-0.6	0.2	0.3	1.1	0.3	-1.1	-1.1	-0.0
Leg pain on walking	0.8	1.0	5.3	-0.7	0.3	1.0	-0.9	-0.3	2.3	-1.9	-0.2	1.2	-0.0	0.5	0.1	-0.4
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.7	-0.5	1.3	1.6	-0.6	-0.6	1.6	-1.2	0.4	1.0	-0.1	-0.7	-0.3	-0.1
Knee pain experienced in last month	0.8	1.3	4.2	0.2	-1.1	-0.9	-1.2	-2.1	0.8	-0.6	-1.6	-1.4	-1.0	0.6	0.4	-1.2
Illnesses of father: Heart disease	0.8	1.1	3.9	-1.2	0.3	0.9	1.3	0.1	-1.1	2.0	1.0	-1.3	0.4	0.4	1.3	0.7
Commuting to job workplace: Walk	0.8	0.9	3.7	-1.2	-1.6	-0.9	-1.0	-0.6	1.9	-0.7	-0.3	-0.2	-0.5	0.0	0.4	-0.6
Eye problems/disorders: Cataract	0.8	0.9	5.9	-1.0	1.1	-0.9	0.0	0.7	0.4	0.1	0.3	-0.3	0.1	-2.4	-1.0	-1.1
Back pain experienced in last month	0.8	1.2	7.1	-0.0	0.7	0.4	-0.3	-0.2	2.7	-1.4	0.4	0.3	-1.1	-1.8	-0.8	-0.2
Average weekly champagne plus white wine intake	0.8	1.1	4.2	-1.9	-1.1	-0.3	-1.3	-0.7	-0.2	-2.0	-0.3	0.8	-0.1	0.2	-0.8	-1.1
Medication: Blood pressure	0.8	1.4	4.8	0.2	-0.6	-1.6	1.2	0.4	-1.3	1.8	-1.4	-2.2	0.3	0.8	1.3	0.2
Arm fat-free mass (left)	0.8	4.1	13.9	-1.0	-2.3	-2.5	-1.2	-1.2	1.6	-3.7	-1.6	-0.4	-2.5	-1.6	-2.4	-2.0
Irritability	0.8	1.3	3.6	1.8	1.5	0.5	0.4	0.3	-1.7	0.3	-0.3	-1.9	-1.1	-1.5	-0.5	-1.0
Worry (Nagel 2018)	0.7	1.5	5.6	2.4	2.1	-0.2	1.8	0.8	0.6	1.0	0.9	-0.6	-0.1	-1.2	-0.7	1.3
Prostate Cancer	0.7	0.9	3.5	-0.5	0.4	1.3	-0.5	-0.8	1.9	-1.3	0.1	1.7	0.2	-0.4	-0.1	0.8
Mean Putamen Volume	0.7	0.8	2.4	-0.4	1.0	1.0	-0.3	-0.0	1.3	-0.2	1.5	1.4	1.0	-0.2	0.8	0.3
LDL Cholesterol	0.7	1.1	3.5	1.8	-0.8	-0.9	-0.2	-0.8	-0.0	-0.7	-1.9	-1.0	-1.2	-0.8	-1.2	-0.7
Respiratory disease	0.7	1.5	4.2	-1.3	-1.4	-1.2	-1.8	-2.0	-0.3	-0.7	-0.7	-0.9	-1.1	1.6	0.4	-0.9
Impedance of leg (right)	0.7	3.4	9.6	2.1	3.1	2.8	1.4	2.0	2.0	1.9	2.0	0.4	0.8	-2.0	0.3	0.1
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.7	1.6	1.0	0.8	0.9	1.3	0.5	-0.8	-0.3	-0.7	-0.9	-0.3	-1.4	0.0
Serious illness, injury or assault to yourself	0.7	0.9	2.9	-0.0	1.0	1.1	1.6	1.2	0.1	1.7	1.3	-0.7	-0.3	-0.5	-0.2	0.2
Stomach or abdominal pain in last month	0.7	0.9	1.9	-0.9	0.8	0.9	1.4	0.9	0.6	1.1	1.3	0.6	0.6	0.5	0.8	1.4
Medication: Levothyroxine sodium	0.7	1.2	4.4	0.3	-2.1	-0.6	-1.4	-1.2	1.4	-1.0	-2.0	-0.4	-0.3	-0.4	-0.6	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	3.7	0.5	1.2	1.8	1.2	0.7	1.8	0.8	1.4	1.9	0.8	0.6	0.5	1.5
Pulse rate	0.7	1.2	3.9	0.7	0.5	1.5	1.6	0.9	-1.0	2.0	1.4	-0.4	0.8	-0.2	0.0	1.4
Pulse wave Arterial Stiffness index	0.7	0.9	3.9	-0.4	-0.2	1.4	-1.1	-0.4	0.3	-1.6	0.2	0.7	-0.1	-0.8	-0.1	-2.0
Hair/balding pattern: Pattern 4	0.7	1.8	8.8	0.2	1.4	-0.8	1.2	3.0	-1.1	1.0	0.7	0.7	0.2	-2.3	-1.4	-0.6
Headache pain in last month	0.7	1.3	4.2	0.7	1.6	0.5	1.3	1.6	0.4	1.4	2.1	0.3	0.4	-0.7	0.5	1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	2.8	-0.7	0.9	0.3	0.9	1.6	-0.1	-0.6	0.2	-0.9	-1.2	-1.7	-0.6	-0.2
Pulse wave peak to peak time	0.7	0.8	4.2	0.3	0.5	-1.1	1.3	0.6	-0.1	1.5	0.1	-0.5	0.1	0.5	0.1	2.0
Neck or shoulder pain in last month	0.7	1.0	3.7	0.1	0.7	1.3	0.3	0.4	0.3	1.7	1.9	0.5	1.2	-0.0	1.5	-0.2
Arm predicted mass (right)	0.7	3.7	13.2	-1.0	-2.6	-2.2	-1.2	-1.2	1.7	-3.6	-1.4	-0.5	-2.5	-1.3	-1.8	-1.8
Suffer from ‘nerves’	0.7	1.1	3.6	1.9	1.8	0.6	1.6	0.7	0.3	0.8	1.4	0.1	0.0	-1.1	-0.5	0.7
Qualifications: nursing, teaching	0.7	1.2	3.3	1.3	-0.2	-0.3	0.5	0.3	-0.1	-1.8	-0.1	-0.7	-1.8	-1.6	-1.8	-0.5
Ever taken oral contraceptive pill	0.7	0.8	2.9	-0.4	1.3	1.2	0.7	1.7	0.3	-0.3	1.3	1.2	0.3	0.2	0.1	0.0
Average weekly beer plus cider intake	0.7	1.1	3.4	-0.1	-1.8	0.4	-1.1	-1.0	1.4	-0.9	-0.3	0.1	-0.3	-1.4	-0.1	-1.8
Arm predicted mass (left)	0.7	3.6	11.3	-0.6	-2.5	-2.5	-1.1	-1.5	1.4	-3.4	-1.6	-0.6	-2.4	-1.2	-2.0	-1.6
Crohns Disease (2017)	0.6	1.2	3.5	0.5	-0.5	1.3	-1.4	-0.5	1.5	-0.2	1.6	0.9	1.0	1.0	1.9	0.4
Irritable Bowel Disease (IBD)	0.6	1.5	5.3	1.0	1.2	2.3	-0.3	0.2	1.5	0.5	1.9	1.1	0.9	-0.0	1.8	0.6
Ulcerative Colitis (UC)	0.6	1.0	4.6	0.9	1.9	2.1	0.3	0.1	0.9	0.8	0.7	0.8	0.7	-0.3	1.0	0.4
Lupus	0.6	1.0	2.7	0.9	0.2	-1.4	-0.3	-1.0	0.9	-0.5	0.5	-0.3	-1.4	-1.6	-1.4	-0.7
Height	0.6	12.2	39.9	2.8	4.9	2.5	6.3	5.0	3.2	1.4	4.1	1.4	0.4	-4.1	-1.2	2.6
Smoking Status	0.6	1.4	6.3	-0.6	-1.0	-0.3	0.3	0.0	-2.5	1.7	-2.2	-1.0	0.6	0.1	1.0	0.2
Cardiovascular Disease	0.6	2.0	8.6	0.6	-0.1	-0.7	2.9	0.7	-2.0	2.0	-0.3	-1.4	0.2	1.7	0.4	1.6
Neuroticism	0.6	1.4	6.2	2.5	1.4	0.1	0.6	-0.1	1.0	0.0	0.8	-1.0	-1.2	-2.0	-1.4	-0.3
Ever used hormone-replacement therapy (HRT)	0.6	0.8	2.6	1.4	0.4	-0.7	-0.0	0.9	-1.6	0.7	-1.0	-1.4	0.1	-0.6	0.1	-0.4
Vitamin and mineral supplements	0.6	0.8	2.2	1.1	-0.3	1.5	1.1	1.0	-0.5	0.6	1.3	-0.4	0.7	0.6	0.9	0.9
Diabetes (father)	0.6	0.7	5.0	-2.2	-0.6	-1.0	-0.0	-0.2	-0.9	0.3	-0.8	0.4	0.8	0.3	-0.2	0.5
Severe depression (siblings)	0.6	0.6	4.8	0.5	2.2	0.1	0.6	1.0	0.1	1.0	0.6	0.4	-0.3	-0.2	-0.2	0.2
Sitting height	0.6	4.5	16.6	1.9	2.4	-1.1	4.1	2.2	0.7	-0.3	2.0	-0.5	-2.0	-3.5	-2.2	0.2
Body mass index (BMI)	0.6	2.4	5.9	-1.2	-2.3	-0.8	-2.4	-2.4	0.6	-2.4	-1.6	0.5	-0.5	1.4	-0.2	-1.1
Impedance of leg (left)	0.6	3.1	8.5	1.9	2.9	2.5	1.3	1.7	2.2	2.0	2.0	0.8	1.1	-1.7	0.3	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	3.3	1.1	1.5	-0.0	-0.4	-0.5	1.0	-0.6	-0.1	-0.5	-0.5	-1.8	-1.7	-1.0
Fluid intelligence score	0.6	1.2	6.0	0.4	-0.2	0.2	-0.1	0.9	0.4	-1.5	-0.6	-0.8	-1.1	-2.4	-1.6	-1.5
Neuroticism score	0.6	1.3	4.6	1.9	2.1	0.4	0.9	0.5	1.0	1.1	1.1	-0.7	-0.2	-1.9	-0.5	0.3
Time employed in main current job	0.6	0.7	2.5	-0.2	-1.0	-0.1	-1.1	-1.3	-0.9	0.4	-0.7	-0.4	0.1	1.6	0.7	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	4.7	2.2	1.3	-1.2	0.7	0.7	0.7	0.2	1.0	-0.8	-0.9	-0.4	-0.7	-0.3
Falls in the last year	0.6	0.8	2.7	1.3	-0.2	-1.2	-1.1	-0.6	0.3	1.7	-0.5	0.7	1.3	0.1	0.2	-0.9
Standing height	0.6	5.7	20.6	1.6	3.0	0.1	3.9	3.1	2.0	-0.4	2.4	0.4	-1.1	-4.5	-2.4	0.3
Tense / ‘highly strung’	0.6	1.0	4.9	2.2	1.8	-0.9	0.7	-0.2	-0.1	1.3	0.3	-0.7	0.0	-1.2	-0.7	0.0
Exposure to tobacco smoke outside home	0.6	0.8	3.8	-0.8	-0.8	-0.4	-1.4	-1.9	0.2	-0.8	-0.6	0.0	-0.5	-0.4	-1.0	-1.0
Eye problems/disorders: None of the above	0.6	0.7	3.3	1.0	-1.8	0.0	-0.7	-1.0	-1.5	-0.7	-0.0	-0.3	-0.6	0.4	0.3	-0.6
Migraine (self-reported)	0.6	0.7	1.6	-1.1	-0.5	0.1	-1.1	-1.0	1.1	1.0	0.1	0.5	1.3	0.8	0.9	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	4.2	0.1	0.0	0.1	0.3	0.6	-1.3	1.1	-0.6	-2.0	-0.9	0.1	-0.4	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	3.3	0.2	-1.2	0.4	-0.7	-0.7	1.1	0.4	0.3	0.3	0.1	1.8	1.2	-0.1
Handedness (chirality/laterality): Left-handed	0.6	0.7	3.8	-1.9	0.9	-0.1	-0.2	-0.2	0.3	0.1	1.2	1.6	0.1	0.5	-0.1	0.3
Long-standing illness, disability or infirmity	0.6	0.8	3.1	-0.0	1.8	1.2	1.6	0.7	0.3	1.1	1.0	-0.2	0.4	-0.3	-0.1	0.8
Mother’s age at death	0.6	0.8	3.0	0.4	1.7	1.3	0.4	0.7	1.5	0.0	0.9	0.6	0.1	-0.9	-0.7	-0.2
Financial situation satisfaction	0.6	0.8	3.7	-1.9	-0.8	0.6	-0.7	0.6	0.7	0.1	0.4	1.2	1.0	0.6	1.0	-0.5
Commuting to job workplace: Public transport	0.6	0.7	2.6	-0.4	-0.1	-1.6	0.6	0.6	-1.0	0.3	-0.1	-0.9	-0.6	-0.8	-1.6	0.1
Medication: Paracetamol	0.6	0.9	3.3	-0.1	-1.0	-0.1	0.2	-0.1	-0.6	1.8	-1.4	-1.0	0.9	0.9	1.3	0.9
Ever smoked	0.6	1.1	4.4	-0.6	-0.6	-1.0	-0.0	-0.7	-2.1	1.5	-1.9	-1.2	0.3	0.0	0.5	0.0
Number of operations (self-reported)	0.6	0.9	5.2	0.5	2.3	-0.5	1.0	1.1	0.3	-0.2	0.1	-0.3	-0.9	-1.2	-1.2	-0.5
Age started oral contraceptive pill	0.6	0.8	2.9	1.6	-0.2	0.7	-1.1	-0.5	1.7	-1.3	-0.2	-0.1	-0.4	-0.6	0.4	-0.8
Depression (Nagel 2018)	0.5	0.7	2.4	0.6	1.4	-0.5	-0.3	-0.6	0.9	0.9	1.1	0.7	1.5	-0.5	0.3	0.1
Neuroticism (Nagel 2018)	0.5	1.1	4.4	2.1	1.6	-0.1	1.1	0.7	1.0	0.4	0.7	-0.6	-0.5	-1.5	-0.8	0.2
Schizophrenia vs Biploar Disorder	0.5	0.6	1.8	0.2	-0.5	1.0	-1.2	-1.3	1.3	-0.3	-0.1	1.0	0.3	0.3	0.9	0.3
Alzheimer’s Disease (in father)	0.5	0.6	2.2	1.3	-0.2	1.0	-0.6	-0.8	1.5	-0.5	0.6	0.8	-0.1	-0.0	-0.0	-0.3
Major Depression (MDD)	0.5	0.6	1.7	1.1	1.3	-1.1	0.2	-0.5	-0.3	0.9	0.9	0.7	0.9	-0.3	0.6	0.6
Ovarian Cancer	0.5	0.6	2.5	0.0	-0.3	0.2	-1.4	-1.1	1.1	-1.6	-0.0	0.4	-0.9	0.1	-0.3	-0.5
Systolic Blood Pressure	0.5	2.6	7.2	-0.1	1.0	-2.3	2.3	0.0	-2.7	2.1	-1.1	-2.6	-0.7	0.3	-1.3	0.1
Townsend deprivation index at recruitment	0.5	0.7	1.7	-0.6	-1.2	-1.1	-0.6	-1.1	-1.0	0.1	-0.6	-0.6	-0.1	1.3	0.7	0.0
Taking other prescription medications	0.5	0.8	2.2	0.3	1.5	0.6	1.0	0.5	1.1	1.5	1.4	0.4	0.4	-0.3	0.7	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	5.4	1.1	0.6	1.4	-0.1	0.2	2.3	-0.2	0.5	2.1	0.9	0.0	-0.0	0.6
Chronic bronchitis/emphysema (father)	0.5	0.6	3.2	0.2	0.0	0.6	-1.0	-0.6	-0.6	-0.7	-0.5	0.9	0.3	1.8	-0.2	-0.6
Past tobacco smoking	0.5	0.9	5.2	0.6	0.3	1.1	-0.4	-0.0	2.3	-1.2	1.3	1.1	0.3	0.5	-0.1	0.2
Qualifications: None of the above	0.5	1.0	4.6	0.4	-0.4	-0.7	0.8	-0.5	-0.6	0.5	-1.7	-2.1	-1.7	0.5	-0.7	0.1
Financial difficulties in last 2 years	0.5	0.7	2.1	-0.1	-0.6	0.1	-0.9	-1.0	-0.1	1.5	0.5	0.1	1.0	0.9	1.4	-0.2
Father’s age at death	0.5	0.7	2.0	-0.9	-0.0	0.6	-1.1	-0.7	0.0	-0.6	-0.8	1.4	0.5	-0.7	-1.3	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.5	-0.5	1.1	-0.2	0.3	-0.5	0.5	-0.9	-0.1	0.6	-1.2	-1.2	-0.8	-0.5
Mouth/teeth dental problems: Dentures	0.5	0.9	2.2	0.8	-0.5	-1.5	-1.0	-0.9	0.2	-1.2	-0.5	-0.1	-1.5	-1.2	-1.0	-0.6
Depression (self-reported)	0.5	0.6	1.6	0.8	0.5	-1.2	-1.1	-1.2	-0.1	0.5	-1.1	-0.5	0.2	-0.0	0.4	-0.9
Prospective memory result	0.5	0.6	1.6	0.2	-0.4	-0.9	0.8	0.5	-1.0	0.6	0.7	-1.3	-1.1	1.2	0.2	0.3
Medication: Paracetamol	0.5	0.8	2.8	0.7	-0.3	-0.2	0.6	-0.2	-0.6	1.7	-1.2	-1.1	0.5	0.7	1.5	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.1	-1.0	1.0	-0.3	1.1	0.6	-0.4	1.4	0.9	-0.9	-0.4	0.0	0.3	0.5
Medication: Allopurinol	0.5	0.7	1.9	0.7	-0.6	-1.0	1.0	0.9	0.1	-0.6	0.7	-1.2	-1.4	-1.0	-0.4	-0.1
Pulse rate, automated reading	0.5	1.6	5.4	-0.4	0.1	2.3	1.4	0.6	-1.8	2.0	1.2	-0.9	0.6	-0.4	1.1	1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.5	0.9	3.0	1.4	1.6	-0.6	1.1	-0.5	-0.1	0.7	1.7	1.1	0.1	0.1	0.5	1.1
Average weekly red wine intake	0.5	0.7	2.1	0.6	-0.2	-0.6	-1.4	-1.4	0.5	-1.3	-0.5	0.5	-0.3	0.6	-1.0	-0.3
Loneliness, isolation	0.5	0.7	2.9	-0.3	1.7	0.4	-0.2	-0.5	0.5	1.5	0.5	1.0	1.4	0.6	0.0	0.3
Medication for cholesterol	0.5	0.7	2.3	-0.0	-0.7	0.2	-1.4	-1.1	0.6	-1.3	-0.4	0.6	-0.5	-0.3	-1.5	-0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.2	0.1	1.5	0.4	1.2	0.2	0.0	0.5	0.8	-0.3	-1.2	0.2	0.1	1.0
Medication: Gliclazide	0.5	0.5	2.2	-1.3	-0.3	0.1	-0.1	0.0	-0.3	1.5	0.2	-0.0	1.1	0.8	0.9	0.3
Alcohol drinker status: Never	0.5	0.6	5.4	2.3	0.2	-0.5	0.0	-0.0	-1.3	-0.4	-0.6	-0.3	-0.1	-0.2	-0.0	-0.2
Fractured/broken bones in last 5 years	0.5	0.7	3.9	0.3	0.1	0.1	1.0	2.0	-1.0	1.1	-0.2	-0.8	-0.8	-0.7	-0.3	-0.4
Diastolic blood pressure, automated reading	0.5	1.4	5.7	-2.4	-1.4	-1.2	-1.0	-1.1	-0.9	-0.3	-1.3	-0.5	0.3	1.3	1.1	-1.0
Pain experienced in last month	0.5	0.8	4.1	-0.5	-1.1	-1.4	-0.8	-0.6	-2.0	-0.0	-0.8	-0.0	-0.1	1.3	-0.0	-0.4
Heart disease (siblings)	0.5	0.7	2.1	1.3	-0.3	0.3	-0.1	1.0	0.6	-1.5	0.6	-0.1	-0.8	-0.8	0.4	-1.1
Reaction Time	0.4	0.7	2.4	-0.7	1.6	0.7	1.5	0.4	1.1	0.1	0.5	0.7	0.4	0.2	-0.1	1.0
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.1	-0.5	-0.1	1.3	0.0	1.4	0.1	-1.4	-0.8	-0.8	-0.4	-1.3	-0.7	-1.2
Triglycerides	0.4	0.6	3.0	-1.7	-0.0	0.1	0.4	-0.6	1.2	0.2	0.3	1.3	0.3	-0.6	0.5	0.7
Ulcerative Colitis	0.4	0.5	1.4	0.9	1.2	0.9	-0.3	-0.4	1.2	0.7	-0.1	0.3	0.7	-0.8	0.5	-0.3
Allergy or Eczema	0.4	1.1	3.2	0.3	1.3	-0.6	0.6	1.6	-1.5	0.4	0.4	-0.1	-0.9	-1.8	-1.6	-0.7
Relative age of first facial hair	0.4	0.9	3.5	0.9	-0.1	-1.1	0.2	0.0	0.7	-1.1	-0.4	-0.4	-1.3	-1.9	-1.2	-0.8
Other serious medical condition/disability diagnosed by doctor	0.4	0.6	2.2	-0.0	1.2	-0.2	1.3	0.4	1.5	0.2	0.6	-0.2	-0.8	-0.6	-0.3	0.5
Maternal smoking around birth	0.4	0.6	2.4	-0.6	-0.5	0.7	-0.8	1.3	-0.3	-0.6	0.5	0.8	0.3	-0.4	0.1	-1.6
Fed-up feelings	0.4	0.8	4.3	0.6	1.2	2.1	-0.6	-0.4	1.3	-0.1	1.0	0.7	0.2	-0.3	0.1	-0.4
Age when periods started (menarche)	0.4	1.0	2.6	1.4	0.4	0.4	1.6	1.5	-0.3	0.1	1.2	-0.5	-1.2	-1.6	0.0	0.6
Medication: Atenolol	0.4	0.5	2.1	-1.1	1.4	-0.2	0.3	-0.0	-0.5	-0.6	-0.4	-0.3	-0.4	-1.1	-0.9	-0.4
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.0	-0.8	-0.9	-0.9	-1.4	-0.3	-0.2	0.1	0.4	1.2	0.0	1.0	-0.0	0.0
Medication: Ramipril	0.4	0.6	3.5	1.9	-0.5	-0.8	0.9	0.9	-0.9	0.3	-0.1	-0.1	0.0	0.3	-0.3	-0.2
Trunk fat-free mass	0.4	2.5	8.8	-0.5	-1.5	-2.2	0.1	-0.3	1.5	-3.0	-0.6	-0.2	-2.2	-1.7	-2.1	-1.1
Hip circumference	0.4	1.5	7.5	-1.0	-0.2	-0.4	-1.2	-0.9	1.7	-2.7	-0.4	1.5	-0.6	-0.8	-1.5	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	4.1	1.2	-0.9	-2.0	0.9	-0.1	-1.4	2.0	-0.3	-1.2	0.8	0.8	0.8	0.2
Trunk predicted mass	0.4	2.5	8.8	-0.5	-1.5	-2.2	0.1	-0.3	1.5	-3.0	-0.7	-0.2	-2.2	-1.8	-2.2	-1.1
Exposure to tobacco smoke at home	0.4	0.4	1.6	0.6	-1.2	-0.3	-0.6	-0.9	-0.5	0.7	-0.6	-0.3	0.4	0.3	1.0	0.1
Peak expiratory flow (PEF)	0.4	0.9	2.6	0.6	-1.4	-1.2	0.8	1.1	-0.7	1.6	0.1	-0.6	1.1	0.8	0.7	0.2
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.6	-1.0	-0.9	-0.5	-0.9	-0.1	0.0	-1.0	-0.5	0.5	-0.6	0.4	0.1	-1.2
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.1	-0.6	0.7	0.2	0.5	0.4	0.8	-1.1	0.7	1.5	-0.6	-0.8	-1.1	0.8
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	4.7	-0.2	-2.2	0.1	-0.4	-1.2	0.8	0.2	-1.3	-0.4	0.6	0.2	0.4	0.7
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.4	-1.1	-0.1	0.2	0.8	0.0	1.2	0.5	0.6	0.8	-0.1	0.0	0.5	1.2
Comparative body size at age 10	0.4	1.2	5.2	0.5	-2.3	-0.3	-0.2	0.3	-1.5	-0.0	-0.7	-1.1	0.9	1.7	1.4	-0.0
Medication: Ibuprofen	0.4	0.4	1.4	1.2	0.4	-0.0	-0.3	-0.5	-0.7	1.2	0.4	-0.4	0.5	0.7	0.8	0.5
Medication: Seretide 50 evohaler	0.4	0.4	1.5	-0.8	1.2	0.9	0.4	0.5	0.4	0.6	0.7	0.2	0.1	-1.0	0.0	-0.2
Number of full sisters	0.4	0.5	1.9	0.8	-0.2	0.2	-1.2	0.2	0.9	-0.9	-0.1	0.7	0.2	0.4	0.7	-1.4
Overall health rating	0.4	0.8	4.7	1.5	1.1	0.7	0.7	-0.1	2.2	0.5	0.9	-0.1	-0.0	-0.3	0.3	0.2
Whole body fat-free mass	0.4	2.3	8.0	-0.8	-1.7	-2.4	-0.1	-0.7	1.1	-2.8	-0.8	-0.2	-2.0	-1.2	-1.9	-0.9
Osteoarthritis (self-reported)	0.4	0.6	1.5	0.7	-0.3	-1.2	0.4	0.1	1.1	-1.0	-0.2	-0.2	-1.2	-0.3	-1.2	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	3.9	0.7	0.3	-0.2	0.6	-0.2	-0.6	2.0	-0.0	-0.4	1.5	1.1	1.0	0.8
Whole body water mass	0.4	2.4	8.5	-0.8	-1.8	-2.4	-0.2	-0.8	1.0	-2.9	-1.0	-0.2	-2.1	-1.1	-2.0	-1.0
Wears glasses or contact lenses	0.4	0.4	1.7	0.7	0.3	0.5	-0.1	1.1	0.7	-0.1	-0.2	-1.3	-0.7	-0.8	-0.3	-0.5
Hearing aid user	0.4	0.4	1.3	1.1	-0.6	-0.4	-0.4	-0.6	-0.7	-0.1	-0.4	-1.1	0.3	-0.3	1.1	-0.0
Basal metabolic rate	0.4	2.1	7.9	-0.8	-1.6	-2.2	-0.3	-0.9	1.1	-2.8	-0.8	-0.1	-1.9	-1.0	-1.9	-1.0
Bipolar Disorder (2018)	0.3	0.5	1.5	-0.8	-0.1	-1.1	-1.0	-1.2	0.7	-0.9	0.0	0.2	-0.3	0.1	-0.5	-0.8
Schizophrenia (2018)	0.3	0.5	2.1	-0.6	-0.7	1.4	-0.4	-0.8	-0.0	-0.4	-0.5	-0.2	0.2	0.7	1.4	0.3
Breast Cancer	0.3	0.7	2.6	-0.3	-1.2	0.2	-0.3	0.7	1.4	0.1	0.2	0.6	1.1	-1.6	-0.8	-0.6
Bipolar Disorder (2011)	0.3	0.3	1.2	1.1	-0.1	-0.2	-0.5	0.2	0.3	-1.1	-0.1	0.3	-0.3	0.4	-0.6	-0.6
Lung FVC	0.3	1.6	8.9	-0.0	-1.9	-1.4	0.9	0.4	-3.0	1.2	-1.2	-1.4	0.5	0.3	-0.2	-0.4
Chronotype (morning person)	0.3	0.6	4.4	0.1	-0.6	-2.1	-0.9	-0.1	0.0	-0.5	-0.8	-0.5	-0.3	-0.0	-0.8	-0.7
Qualifications: CSEs or equivalent	0.3	0.4	1.3	0.0	0.3	0.2	-0.3	-0.6	0.8	1.0	-0.4	1.1	0.5	0.9	0.4	0.3
Multivitamins +/- minerals	0.3	0.3	1.3	0.6	0.4	-1.2	-0.3	-0.7	0.3	0.3	-1.0	-0.4	-0.7	0.3	-0.4	-0.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	0.7	-0.9	-0.8	-0.8	-0.6	-0.7	-0.4	0.6	-0.8	0.5	0.5	-0.3	-0.5	0.0
High blood pressure (mother)	0.3	0.4	1.5	0.0	0.2	-0.9	1.2	0.3	-0.5	0.7	-0.1	-1.2	-0.6	-0.4	-0.3	0.4
Waist circumference	0.3	1.1	4.2	-1.1	-0.8	-0.4	-1.1	-0.7	1.0	-2.0	-0.7	0.1	-1.1	-0.9	-1.1	-1.3
Forced vital capacity (FVC)	0.3	1.2	3.4	0.7	-1.2	-1.5	1.5	0.3	-1.7	1.8	-0.3	-1.0	0.8	0.5	0.8	0.4
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	2.1	1.5	0.9	0.1	-0.4	-0.4	-0.4	-0.2	-0.4	-0.4	-0.3	0.2	-0.3	-0.6
Hair/balding pattern: Pattern 3	0.3	0.5	2.2	-0.8	-0.4	-1.5	0.4	1.2	-1.1	-0.3	0.1	-0.5	0.2	-0.2	-0.6	0.1
Forced expiratory volume in 1-second (FEV1)	0.3	1.1	2.7	0.8	-1.6	-1.4	0.8	-0.1	-1.3	1.5	-0.5	-1.1	0.7	1.0	0.9	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	3.5	1.9	0.4	-0.1	-0.3	-0.1	-0.6	0.7	0.0	-0.6	0.2	0.4	0.3	0.5
Birth weight of first child	0.3	0.5	1.3	-0.1	0.1	0.6	-0.3	0.6	0.5	-0.6	0.4	1.1	0.8	-1.1	-1.0	-0.7
Blood clot in the leg (DVT)	0.3	0.4	1.3	0.2	0.2	-1.0	-0.8	0.1	1.1	0.5	0.3	0.0	0.3	-0.7	0.3	-1.0
Gout (self-reported)	0.3	0.4	2.8	-0.1	-0.7	-1.7	-0.1	-0.0	-0.0	-0.3	-0.3	-0.6	-0.5	-0.7	-0.4	-0.1
Forced vital capacity (FVC), Best measure	0.3	1.3	4.5	1.4	-0.5	-1.6	1.3	-0.0	-1.4	2.1	-0.2	-1.3	0.8	0.0	0.9	0.6
Wheeze or whistling in the chest in last year	0.3	0.5	2.7	-1.6	-0.7	0.5	0.4	0.5	-0.1	0.4	0.7	-0.8	-0.6	0.6	1.0	0.1
Shortness of breath walking on level ground	0.3	0.4	1.8	0.6	0.4	0.2	-0.1	-0.7	-0.1	0.0	-0.2	-1.3	-1.1	0.7	0.0	-0.3
Mouth/teeth dental problems: Loose teeth	0.3	0.4	1.9	0.0	0.7	1.4	0.1	-0.3	-0.1	0.5	0.3	0.3	0.0	1.0	0.9	0.6
Heart disease (mother)	0.3	0.4	1.7	0.7	0.8	0.6	0.6	0.5	-0.1	0.3	0.1	-0.8	-0.3	-1.3	-0.4	-0.3
Comparative height size at age 10	0.3	1.6	4.3	1.8	2.1	-0.2	1.7	0.3	1.6	-0.4	-0.0	-0.3	-0.8	-2.0	-1.5	-0.0
Chest pain or discomfort	0.3	0.5	2.3	-0.8	-0.4	-0.2	0.6	1.5	-0.2	-0.0	0.0	-1.2	-0.1	-0.3	0.8	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	1.2	0.2	-0.4	0.1	-0.9	-1.1	-0.3	-0.0	-0.4	0.5	0.1	-0.7	-0.2	-1.1
Smoking status: Previous	0.3	0.4	2.6	-0.2	-0.4	-1.0	0.4	0.2	-1.6	0.5	-0.7	-0.5	-0.6	-0.4	0.0	-0.3
Mood swings	0.3	0.5	2.8	0.7	-0.2	0.6	-0.9	-1.7	-0.3	0.6	-0.3	-0.8	-0.3	-0.7	0.7	-0.5
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.9	0.8	1.2	0.7	-0.1	0.2	1.4	-0.0	1.3	0.6	0.1	-0.4	0.2	0.0
Asthma (self-reported)	0.3	0.6	2.7	-0.9	0.3	0.5	-0.4	-1.7	0.3	0.2	0.3	-0.3	-0.3	1.6	0.4	0.6
Miserableness	0.3	0.6	1.7	1.3	0.7	-0.2	1.0	0.3	-0.9	1.0	-0.2	-1.1	-0.5	-0.1	-0.2	0.7
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.0	-0.4	0.9	-0.8	-0.4	-0.5	1.0	0.8	0.9	0.1	0.1	-0.3	0.9	0.7
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.3	0.5	0.2	-0.9	-0.9	0.0	1.1	0.4	0.2	-0.2	0.0	-0.8	0.2	-1.1
Bipolar Disorder or Schizophrenia	0.2	0.5	1.9	-1.0	-0.6	0.5	-1.0	-1.4	0.5	-0.8	-0.4	-0.0	-0.1	0.6	0.8	-0.3
Depressed Affect (Nagel 2018)	0.2	0.5	2.6	1.6	0.2	0.7	-0.6	-0.6	1.3	0.4	0.2	-0.2	0.3	-0.4	0.5	-0.3
Intelligence (Savage-Jansen 2018)	0.2	0.7	4.2	-2.0	0.4	0.7	0.7	1.4	-0.5	0.2	-0.4	0.6	0.7	0.2	0.5	0.2
Alzheimer’s Disease (in mother)	0.2	0.2	0.6	-0.7	-0.6	-0.1	-0.5	-0.4	0.5	-0.7	0.0	0.0	-0.5	-0.1	-0.5	-0.8
Alzheimer’s Disease (including proxy)	0.2	0.2	0.5	0.6	-0.6	0.2	-0.4	0.0	0.7	0.0	0.6	0.7	0.6	0.5	0.2	-0.2
Schizophrenia (2014)	0.2	0.5	1.4	-0.1	-0.3	1.2	-1.0	-0.8	1.2	-0.9	-0.6	0.4	0.2	0.0	0.9	-0.6
Blood Eosinophil Count	0.2	1.5	7.4	2.7	1.2	0.1	0.5	2.4	1.1	-0.3	-0.3	-0.2	-0.9	-0.9	-1.4	-0.4
Blood White Count	0.2	1.7	4.4	-0.8	1.6	1.6	-0.6	-0.3	1.2	-0.5	1.4	2.1	1.9	0.0	1.9	0.5
Heel T-Score	0.2	1.4	6.0	0.5	-0.4	-1.0	0.7	0.5	-2.5	2.1	-1.8	-1.1	0.4	0.5	-0.1	0.6
Waist Hip Ratio (WHR)	0.2	1.0	2.8	0.2	0.6	0.1	1.6	1.4	-1.1	1.4	1.0	-1.7	-0.5	-0.4	0.6	0.1
Frequency of depressed mood in last 2 weeks	0.2	0.3	2.3	0.3	1.5	0.1	0.4	-0.4	0.1	0.9	0.7	-0.3	-0.1	-0.2	0.1	0.1
Systolic blood pressure, automated reading	0.2	0.5	1.7	-0.0	0.6	-1.3	0.4	-0.1	-0.9	-0.0	-1.0	-0.7	-0.4	-0.2	-0.7	-0.9
Leg fat-free mass (left)	0.2	1.2	4.3	-0.9	-1.2	-2.0	0.2	-0.7	0.2	-2.1	-0.5	-0.1	-1.4	-0.5	-1.3	-0.1
Hand grip strength (right)	0.2	0.5	2.2	0.6	-0.1	-0.9	0.7	-0.2	0.7	-0.5	-0.7	0.3	0.1	-1.5	-1.0	0.2
Current tobacco smoking	0.2	0.4	2.0	-0.2	0.1	0.1	0.8	0.6	-1.4	0.7	-0.8	-0.2	0.5	0.1	0.2	0.6
Hayfever, allergic rhinitis or eczema	0.2	0.4	2.1	-0.4	0.6	-0.0	0.1	0.8	-1.1	0.2	-0.0	0.2	-0.7	-0.3	-1.4	-0.2
Leg predicted mass (left)	0.2	1.2	4.4	-0.9	-1.3	-2.0	0.2	-0.8	0.2	-2.1	-0.5	-0.1	-1.4	-0.4	-1.3	-0.1
Alcohol usually taken with meals	0.2	0.3	1.8	0.8	0.4	0.3	-0.2	-1.3	-0.0	-0.0	0.5	0.1	0.3	0.0	0.4	0.9
Mouth/teeth dental problems	0.2	0.3	1.4	-1.0	-0.9	-0.1	-0.1	-0.1	-0.6	-0.3	-1.2	-0.3	-0.1	0.4	-0.2	-0.6
Allergy	0.2	0.4	1.5	1.1	-0.5	0.5	0.3	-0.4	0.6	0.1	-0.1	0.1	0.8	0.6	1.2	0.9
Weight	0.2	1.1	5.8	-0.6	-0.9	-0.6	-0.6	-0.9	1.4	-2.4	-0.4	0.6	-1.0	-0.7	-1.2	-0.8
Alcohol intake versus 10 years previously	0.2	0.2	1.4	-0.4	1.2	0.6	0.7	-0.3	-0.2	0.4	0.6	-0.3	-0.3	-0.1	0.0	0.2
Asthma	0.2	0.5	2.6	-0.6	0.5	0.4	-0.6	-1.6	0.7	-0.2	0.3	-0.1	-0.3	1.1	0.1	0.5
Arm fat mass (right)	0.2	0.7	3.1	-0.6	-1.1	-0.3	-0.9	-1.3	0.7	-1.7	-0.7	0.6	-0.5	0.4	-0.7	-0.4
Breastfed as a baby	0.2	0.2	0.7	-0.3	0.6	0.7	-0.6	-0.4	0.8	-0.2	-0.4	-0.2	-0.1	-0.7	-0.2	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.4	0.3	1.1	0.1	0.5	-0.0	0.1	1.2	0.1	0.1	0.5	0.4	0.1	0.1
Birth weight	0.2	0.4	1.3	-0.5	-0.2	-1.2	-0.6	-0.3	-1.1	-0.8	0.2	-0.6	-0.9	-0.1	-0.2	-0.8
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.0	-0.6	-0.4	0.1	0.2	0.6	-0.4	0.1	-0.3	-1.0	-0.4	0.0	-0.2	-0.9
Qualifications: College or University degree	0.2	0.8	1.9	-1.0	0.6	0.5	-0.6	0.1	-1.1	0.0	0.7	1.4	1.4	0.8	0.9	0.9
Emphysema/chronic bronchitis	0.2	0.2	0.6	-0.4	-0.3	-0.5	-0.6	-0.3	-0.3	0.2	-0.0	0.7	0.8	0.3	0.8	0.2
Leg fat mass (right)	0.2	0.6	3.2	-0.4	-0.5	-0.1	-0.5	-0.4	1.2	-1.8	-0.2	0.4	-0.8	-0.3	-0.8	-0.7
Alcohol intake frequency.	0.2	0.5	2.2	0.4	0.2	0.1	0.6	0.2	-0.2	-0.7	-0.2	-1.4	-1.5	-0.2	-0.9	-0.6
Age at last live birth	0.2	0.3	1.2	0.3	-0.7	0.8	0.6	0.2	-0.6	0.5	0.7	0.2	0.0	0.6	0.4	1.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	1.2	-0.4	-0.4	-0.4	0.5	0.6	-0.0	0.0	0.3	-1.1	-0.0	0.2	0.4	0.6
Leg fat-free mass (right)	0.2	1.3	5.2	-1.1	-1.3	-2.3	0.1	-1.0	0.1	-2.0	-0.6	0.1	-1.3	-0.2	-1.3	-0.0
Mineral and other dietary supplements	0.2	0.3	1.3	0.2	-0.2	1.1	0.6	0.4	-0.6	-0.8	-0.3	0.1	0.3	0.1	-0.5	0.1
Osteoporosis (self-reported)	0.2	0.3	1.3	1.1	-0.4	0.1	-0.6	-0.4	-0.3	-0.3	-0.0	-0.5	0.0	-0.5	0.9	0.0
Smoking status: Current	0.2	0.3	1.5	-0.3	0.0	-0.1	0.5	0.2	-1.2	0.7	-0.9	0.1	0.5	0.3	0.3	0.5
Leg predicted mass (right)	0.2	1.3	5.3	-1.1	-1.3	-2.3	0.1	-1.0	0.1	-2.0	-0.5	0.1	-1.3	-0.3	-1.3	-0.0
Arm fat mass (left)	0.2	0.9	3.9	-0.6	-1.2	-0.3	-1.0	-1.4	0.9	-2.0	-0.7	0.5	-0.5	0.3	-0.7	-0.6
Medication: Bendroflumethiazide	0.2	0.4	1.5	-0.4	0.4	-0.1	-0.9	-0.9	0.7	-0.1	-1.2	-0.3	0.8	-0.0	-0.1	-0.2
Leg fat percentage (left)	0.2	0.7	2.1	-0.2	-0.3	0.6	-1.4	-0.8	1.4	-1.5	-0.5	0.9	-0.1	0.0	-0.5	-0.9
Ever depressed for a whole week	0.2	0.3	2.0	0.1	0.2	0.1	-0.4	-0.5	-1.4	-0.1	-0.8	-0.7	-0.1	0.3	0.0	-0.6
Leg fat mass (left)	0.2	0.7	3.8	-0.4	-0.6	-0.1	-0.7	-0.7	1.4	-1.9	-0.2	0.8	-0.7	-0.2	-0.9	-0.7
Blood Platelet Count	0.1	1.1	5.0	2.2	-1.0	0.1	-1.0	0.2	0.1	-1.3	-1.5	0.4	0.1	-0.9	-0.7	-1.4
Blood Red Count	0.1	0.7	3.7	0.2	-1.1	-1.9	-0.5	0.0	-1.0	0.1	-1.3	-0.8	0.1	-0.5	-0.5	-0.8
Lung FEV1/FVC ratio	0.1	0.7	2.3	0.3	-0.2	-1.5	0.6	0.4	-0.8	1.0	-0.1	0.8	1.3	1.2	0.4	0.6
Hair Pigment	0.1	1.6	6.6	-2.6	0.2	2.0	-0.9	-0.5	1.1	-0.0	-0.3	1.1	1.7	1.6	0.7	0.9
Tanning	0.1	1.0	4.1	-1.2	0.4	-1.0	0.6	0.0	-2.0	1.0	0.2	0.0	0.5	1.7	0.9	1.3
Hand grip strength (left)	0.1	0.4	1.3	-0.2	0.3	-0.6	1.2	0.4	0.5	-0.2	-0.1	0.8	0.5	-0.6	-0.7	0.7
Trunk fat percentage	0.1	0.3	1.1	0.3	0.6	1.1	-0.1	-0.2	1.1	-0.5	0.3	0.9	0.5	0.0	-0.2	0.2
Trunk fat mass	0.1	0.5	1.9	0.1	0.2	0.4	-0.0	-0.2	1.3	-1.4	0.2	0.8	-0.2	-0.6	-0.9	-0.2
Arm fat percentage (right)	0.1	0.3	0.9	-0.3	-0.1	0.6	-0.5	-0.9	0.5	-0.5	-0.1	0.9	0.5	0.9	-0.1	0.3
Qualifications: A levels/AS levels or equivalent	0.1	0.3	1.0	0.2	-0.6	-0.7	0.2	0.8	-0.2	-1.0	0.4	0.2	-0.6	-0.2	-0.9	-0.1
Body fat percentage	0.1	0.4	1.8	0.2	0.3	1.0	-0.5	-0.4	1.3	-0.8	0.2	1.0	0.5	0.2	-0.1	-0.1
Leg fat percentage (right)	0.1	0.5	1.5	-0.0	-0.2	0.8	-1.2	-0.5	1.2	-1.2	-0.5	0.5	-0.1	0.0	-0.4	-0.9
Whole body fat mass	0.1	0.5	2.5	0.1	-0.1	0.1	-0.3	-0.4	1.4	-1.6	0.1	0.7	-0.4	-0.3	-0.8	-0.4
Arm fat percentage (left)	0.1	0.4	1.2	-0.3	-0.3	0.6	-0.7	-1.0	0.7	-1.1	-0.2	0.9	0.3	0.8	-0.2	0.1

Hub : Genes

RNF187

Models

Trait associations