Hub : Genes

RP11-173B14.5

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.2500 0.0570 4.0e-07 0.092 NA 0.064 NA 0.072 5.5e-08 NA 5.8e-06 NA 1.6e-06
2 GTEx Adipose Visceral Omentum 0.1380 0.0550 4.6e-03 0.049 NA 0.053 NA 0.067 1.4e-03 NA 1.0e-03 NA 2.2e-04
3 GTEx Adrenal Gland 0.1890 0.0686 4.0e-03 -0.006 NA 0.007 NA -0.008 6.0e-01 NA 1.7e-01 NA 9.0e-01
4 GTEx Artery Aorta 0.4990 0.0620 8.1e-13 0.434 NA 0.420 NA 0.423 5.7e-26 NA 6.3e-25 NA 3.4e-25
5 GTEx Artery Tibial 0.5969 0.0466 0.0e+00 0.440 NA 0.465 NA 0.312 1.3e-37 NA 2.1e-40 NA 5.9e-25
6 GTEx Brain Caudate basal ganglia 0.2800 0.0940 4.8e-03 0.204 NA 0.113 NA 0.158 1.7e-06 NA 4.0e-04 NA 2.8e-05
7 GTEx Brain Cortex 0.3440 0.1030 2.1e-03 0.226 NA 0.116 NA 0.272 6.8e-07 NA 4.4e-04 NA 3.7e-08
8 GTEx Brain Frontal Cortex BA9 0.2253 0.0864 7.9e-03 0.120 NA 0.061 NA 0.098 4.5e-04 NA 1.1e-02 NA 1.5e-03
9 GTEx Brain Nucleus accumbens basal ganglia 0.2610 0.0870 2.1e-03 0.325 NA 0.175 NA 0.290 1.8e-09 NA 2.0e-05 NA 1.9e-08
10 GTEx Breast Mammary Tissue 0.2770 0.0950 2.2e-04 0.191 NA 0.172 NA 0.164 4.1e-10 NA 3.6e-09 NA 8.5e-09
11 GTEx Breast Mammary Tissue (Male) 0.0887 0.1089 2.5e-01 0.143 NA 0.077 NA 0.132 3.5e-04 NA 7.7e-03 NA 6.0e-04
12 GTEx Breast Mammary Tissue (Female) 0.0127 0.0989 4.6e-01 0.070 NA -0.005 NA 0.085 4.1e-03 NA 5.0e-01 NA 1.6e-03
13 GTEx Cells Transformed fibroblasts 0.5800 0.0510 0.0e+00 0.436 NA 0.450 NA 0.157 1.4e-35 NA 4.7e-37 NA 7.4e-12
14 GTEx Lung 0.2404 0.0518 5.7e-09 0.258 NA 0.223 NA -0.004 8.8e-20 NA 5.3e-17 NA 9.2e-01
15 GTEx Nerve Tibial 0.3882 0.0608 2.2e-12 0.303 NA 0.269 NA 0.281 8.1e-22 NA 3.4e-19 NA 4.6e-20
16 GTEx Prostate 0.4180 0.1200 4.5e-04 0.219 NA 0.009 NA 0.181 3.4e-06 NA 1.9e-01 NA 2.6e-05
17 GTEx Skin Not Sun Exposed Suprapubic 0.1720 0.0650 2.6e-03 0.016 NA 0.014 NA 0.031 4.1e-02 NA 5.6e-02 NA 8.3e-03
18 GTEx Skin Sun Exposed Lower leg 0.1380 0.0440 1.6e-04 0.159 NA 0.107 NA 0.054 4.3e-13 NA 3.7e-09 NA 2.6e-05
19 GTEx Testis 0.6280 0.0650 9.4e-13 0.418 NA 0.405 NA 0.124 4.6e-20 NA 2.6e-19 NA 3.7e-06
20 GTEx Thyroid 0.2840 0.0580 7.7e-11 0.233 NA 0.208 NA 0.231 8.0e-18 NA 7.4e-16 NA 1.3e-17
21 GTEx Vagina 0.5120 0.1210 1.3e-04 0.332 NA 0.456 NA 0.446 2.0e-08 NA 7.3e-12 NA 1.4e-11

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bipolar Disorder (2018) 0.9 1.4 3.0 1.7 1.0 -1.0 1.4 1.3 0.2 0.4 1.6 0.4 1.1 0.7 1.5 1.1 1.5 -1.6 0.3 1.2 1.5 0.9 1.6 1.0
Bipolar Disorder or Schizophrenia 0.4 1.0 2.4 1.4 0.8 0.3 1.2 1.2 0.0 -0.5 1.6 0.6 0.8 0.1 1.2 1.0 1.3 -1.2 0.1 0.7 1.2 1.1 1.4 0.7
Depressed Affect (Nagel 2018) 0.4 0.9 2.9 0.6 1.3 1.3 0.9 0.6 0.9 0.7 1.0 0.9 0.5 0.9 0.8 1.2 0.7 -0.8 0.5 0.7 0.9 1.3 0.9 1.7
Depression (Nagel 2018) 0.2 0.2 1.0 0.4 -0.0 0.8 0.2 -0.1 0.6 0.4 0.7 0.8 -0.3 -0.5 0.3 1.0 -0.0 -0.5 -0.3 0.0 0.3 0.6 0.5 -0.2
Intelligence (Savage-Jansen 2018) 0.2 0.7 4.0 -0.6 0.3 -0.2 -0.3 -0.7 -2.0 -0.3 -0.9 -1.8 0.1 0.4 -0.5 -1.3 -0.5 0.3 0.3 0.1 -0.8 -1.1 -0.7 -0.8
Neuroticism (Nagel 2018) 0.3 0.8 3.2 0.7 1.4 1.8 0.9 0.4 -0.6 0.5 0.5 -0.2 0.4 0.6 0.8 0.9 0.7 -0.8 0.4 0.6 0.6 1.4 0.7 1.6
Schizophrenia (2018) 0.1 0.2 1.5 0.5 0.2 1.2 0.4 0.4 -0.1 -0.9 0.7 0.5 0.1 -0.4 0.4 0.4 0.4 -0.2 -0.1 -0.1 0.4 0.6 0.5 0.1
Schizophrenia vs Biploar Disorder 0.5 0.7 5.6 0.2 0.2 2.4 0.7 0.8 1.0 0.6 0.6 1.1 0.7 0.6 0.6 0.5 0.4 -0.4 0.9 0.4 0.7 0.9 0.8 0.2
Worry (Nagel 2018) 2.3 4.8 8.8 2.5 3.0 2.9 2.5 1.7 -2.0 1.1 1.3 -1.5 1.6 1.8 2.5 1.8 2.4 -2.6 2.0 2.6 1.9 2.4 2.1 2.4
Alzheimer’s Disease (in mother) 2.6 3.0 7.6 -1.5 -2.0 -1.6 -1.7 -1.6 -0.5 -1.0 -1.9 -1.1 -2.8 -2.2 -1.6 -1.5 -1.9 1.6 -2.1 -2.2 -1.7 -2.1 -1.4 -1.4
Alzheimer’s Disease (in father) 0.3 0.3 1.4 0.4 1.1 -1.2 0.4 -0.1 -0.7 -0.3 0.3 -0.5 0.3 -0.9 0.4 0.6 0.3 -0.3 -0.8 0.1 0.2 -0.1 0.3 0.6
Alzheimer’s Disease (including proxy) 1.4 2.1 5.3 -1.0 -0.8 -1.7 -1.2 -1.3 -1.2 -1.0 -1.5 -1.4 -2.2 -2.0 -1.1 -1.0 -1.3 1.1 -2.3 -1.6 -1.3 -1.6 -1.1 -1.3
Crohns Disease (2017) 0.3 0.6 3.2 -0.1 -0.2 0.1 -0.4 -0.7 -1.8 -0.8 -0.8 -1.2 -1.3 -0.3 -0.4 -0.8 -0.2 0.4 -0.4 -0.2 -0.6 -0.3 -0.7 -1.6
Irritable Bowel Disease (IBD) 0.5 1.3 4.1 -0.9 -0.8 -0.9 -1.0 -1.2 -1.3 -0.6 -1.2 -1.0 -1.6 -0.5 -1.1 -1.4 -0.9 1.0 -0.4 -0.7 -1.2 -1.5 -1.1 -2.0
Ulcerative Colitis (UC) 0.2 0.4 2.3 -0.5 -0.3 -1.5 -0.5 -0.4 0.2 0.3 -0.2 0.1 -0.9 -0.0 -0.5 -0.6 -0.4 0.4 0.1 -0.2 -0.4 -1.5 -0.4 -0.9
Major Depression (MDD) 0.5 0.6 1.8 -1.0 -1.4 1.0 -0.7 -0.8 0.6 -0.2 -0.9 0.1 -0.6 -1.2 -0.6 -1.3 -0.9 0.4 -0.2 -0.5 -0.6 -0.2 -0.5 -0.9
Reaction Time 0.4 0.7 1.8 0.8 1.1 -0.9 1.0 0.7 -0.3 1.1 0.4 -0.3 0.7 1.3 0.9 0.6 1.1 -1.0 0.5 1.1 0.8 0.9 0.7 0.7
Verbal and Numeric Reasoning (VNR) 1.1 2.7 5.4 1.8 2.0 1.1 1.9 1.5 -1.7 0.6 1.3 -1.0 2.3 2.0 1.8 1.2 1.9 -1.9 1.8 2.2 1.4 1.2 1.4 1.1
Breast Cancer 0.5 1.1 4.5 0.2 -2.1 -0.1 -1.0 -0.8 -1.0 -0.7 -0.6 -1.0 -1.3 -1.9 -0.8 -0.5 -0.8 0.6 -1.5 -1.5 -0.9 -1.2 -0.6 -0.4
Ovarian Cancer 0.4 0.5 3.5 -0.2 -0.0 -0.4 -0.0 -0.7 -1.7 0.6 -1.3 -1.9 0.3 0.5 -0.2 -1.1 -0.1 0.0 0.3 0.2 -0.6 0.1 -0.2 0.5
Prostate Cancer 5.0 7.0 12.3 3.1 2.9 -0.2 3.0 3.3 1.5 3.5 2.8 1.5 1.8 2.6 2.9 2.4 2.9 -2.8 2.4 3.2 2.9 2.3 3.1 2.2
Age at First Birth 0.5 0.7 1.6 -1.3 -1.0 -0.5 -1.0 -0.6 0.7 -0.5 -0.2 0.7 -0.7 -0.9 -1.1 -0.8 -0.9 1.2 -1.0 -0.8 -0.8 -0.9 -1.0 -0.4
Bipolar Disorder (2011) 2.2 2.1 3.9 1.9 1.2 -0.9 1.7 1.6 -0.2 0.6 1.8 0.4 1.7 1.3 1.7 1.2 1.8 -1.9 1.0 2.0 1.6 1.4 1.6 0.9
Body Mass Index (BMI) (2010) 1.3 1.8 4.7 -1.3 -1.6 -0.2 -1.4 -1.7 -1.2 -2.2 -1.4 -1.2 -0.7 -1.4 -1.4 -1.3 -1.5 1.2 -0.7 -0.9 -1.5 -1.6 -1.4 -1.0
Coronary Artery Disease (CAD) 0.4 0.5 1.2 -0.4 -0.8 -1.1 -0.8 -0.7 0.4 -0.7 -0.0 0.3 -1.1 -0.6 -0.7 -0.5 -0.7 0.5 -0.8 -0.9 -0.6 -0.3 -0.7 -1.0
Crohns Disease (2012) 0.5 0.8 5.6 -0.1 -0.1 0.4 -0.4 -0.7 -2.4 -0.7 -1.1 -1.8 -0.8 -0.3 -0.6 -1.4 -0.3 0.6 0.1 0.3 -0.9 -0.5 -0.8 -0.8
Mean Putamen Volume 0.9 1.0 4.0 0.7 0.4 2.0 0.9 0.5 -0.6 1.1 0.3 -0.7 1.4 1.4 0.9 1.0 0.9 -1.0 1.3 0.7 0.7 1.2 0.7 1.0
Fasting Glucose 0.7 0.8 1.8 -1.0 -0.4 -0.7 -0.8 -1.4 -1.0 -1.1 -1.2 -1.1 -0.1 -0.5 -0.8 -0.6 -0.7 0.6 -1.3 -0.9 -0.9 -0.6 -1.1 -1.0
HbA1C 0.3 0.4 1.2 0.5 1.1 0.6 0.7 0.5 -0.8 0.5 -0.1 -0.7 0.1 0.8 0.5 0.7 0.6 -0.2 0.7 0.3 0.7 0.6 0.7 0.6
HDL Cholesterol 0.1 0.2 0.5 -0.2 -0.3 0.2 -0.5 0.0 -0.0 -0.7 -0.1 0.1 -0.1 -0.5 -0.5 -0.5 -0.3 0.6 -0.1 -0.6 -0.4 -0.7 -0.4 0.1
LDL Cholesterol 1.0 1.6 6.1 -1.7 -0.5 -1.1 -1.3 -1.8 -0.6 -2.5 -1.0 -0.2 -0.6 -0.6 -1.4 -1.2 -1.4 1.4 -0.7 -1.2 -1.3 -1.3 -1.5 -0.1
Lupus 1.1 1.6 4.4 1.0 1.7 2.1 1.3 1.1 -0.2 0.8 1.3 0.4 1.1 1.4 1.2 0.6 1.3 -1.3 1.8 1.7 1.3 1.3 1.1 1.0
Neuroticism (2016) 0.3 0.4 1.3 -0.5 -0.7 0.0 -0.7 -1.1 -0.3 -0.8 -0.7 -0.7 -0.6 -0.2 -0.8 -0.9 -0.7 0.6 -0.2 -0.3 -0.9 -0.0 -0.8 -0.2
Primary Biliary Cirrhosis 0.4 0.5 1.9 -0.8 -1.4 -0.6 -0.6 -0.9 -0.3 -1.3 -0.3 -0.6 -0.6 -0.8 -0.6 -0.7 -0.6 0.6 -0.7 -0.4 -0.7 -0.6 -0.5 -0.8
Rheumatoid Arthritis 0.3 0.4 1.4 0.6 -0.3 -1.0 0.3 0.4 -1.1 1.1 -0.2 -1.2 0.1 0.5 0.3 -0.5 0.7 -0.7 0.8 0.5 0.0 -0.4 0.2 -0.1
Schizophrenia (2014) 0.9 2.0 3.5 1.6 1.5 1.7 1.7 1.7 0.3 0.2 1.9 1.1 1.3 0.6 1.7 1.4 1.7 -1.5 0.7 1.3 1.7 1.8 1.7 0.4
Triglycerides 0.3 0.5 1.6 -0.4 -0.4 0.1 -0.5 -0.9 -1.2 -1.1 -0.7 -0.8 -1.3 -0.7 -0.6 -0.6 -0.5 0.5 -0.6 -0.5 -0.7 -0.6 -0.7 -1.0
Type 2 Diabetes (T2D) (2012) 1.0 1.1 3.1 1.0 1.7 0.1 1.4 1.1 -0.5 0.8 0.9 0.2 1.3 0.7 1.3 1.0 1.3 -1.2 0.3 1.8 1.2 0.7 1.1 1.1
Ulcerative Colitis 0.2 0.3 1.7 -0.0 0.7 -1.3 0.3 0.2 -0.5 1.3 0.1 -0.3 0.0 0.7 0.2 -0.3 0.3 -0.2 0.9 0.7 0.1 -0.9 0.3 0.2
Blood Eosinophil Count 0.1 0.7 3.3 -0.3 -0.3 -1.8 -0.7 -0.3 -0.6 -0.1 -0.8 -0.9 -1.1 0.6 -0.7 -0.3 -0.5 0.8 -0.5 -0.4 -0.9 -0.9 -0.8 -1.5
Blood Platelet Count 0.1 1.0 6.7 0.9 0.8 0.9 0.4 0.1 -2.6 -1.0 -0.4 -2.4 0.0 1.1 0.4 0.2 0.8 -0.1 1.4 0.6 -0.2 0.1 0.1 0.6
Blood Red Count 3.3 31.6 73.4 -5.3 -6.5 -1.2 -5.2 -6.3 -8.6 -4.6 -7.8 -8.0 -4.3 -4.5 -5.1 -6.2 -4.6 4.3 -4.7 -4.9 -6.2 -4.0 -6.4 -4.5
Blood White Count 0.2 1.6 4.5 -1.3 -1.0 -2.1 -1.3 -1.4 -0.4 -0.9 -1.4 -0.7 -1.4 -1.0 -1.2 -1.1 -1.4 1.1 -1.4 -0.9 -1.4 -1.8 -1.3 -0.8
Heel T-Score 0.1 1.1 8.6 -0.5 -1.1 2.9 -0.6 -0.6 -1.9 -1.9 -0.6 -1.2 0.3 -0.6 -0.5 -0.4 -0.4 0.3 1.1 -0.2 -0.7 0.3 -0.5 0.6
BMI 1.2 6.7 12.1 -2.6 -2.8 -2.7 -3.0 -2.8 0.3 -3.4 -2.3 -0.1 -1.8 -2.2 -3.0 -2.5 -2.8 3.0 -2.6 -2.5 -2.7 -3.5 -2.9 -2.0
Height 0.4 8.4 15.6 3.4 1.5 2.5 3.1 3.3 -1.1 3.9 1.9 -0.0 4.0 2.5 3.4 3.1 3.8 -3.4 2.2 2.6 3.4 3.2 2.5 2.6
Waist Hip Ratio (WHR) 0.9 3.9 7.2 2.3 1.4 0.3 1.9 2.7 1.8 2.5 2.3 1.9 1.9 1.2 2.0 1.8 2.1 -2.2 1.0 2.1 2.3 2.3 2.0 1.7
Systolic Blood Pressure 0.2 1.1 2.4 1.6 1.4 1.4 1.0 1.4 0.3 1.1 0.6 0.7 0.5 0.1 1.0 1.0 1.2 -0.9 0.1 0.8 1.2 1.3 0.8 1.5
Smoking Status 0.3 0.8 4.6 1.0 -0.1 -1.0 0.4 1.0 2.1 1.2 1.2 1.3 -0.5 -0.5 0.6 0.2 0.4 -0.6 0.2 0.6 0.8 -0.5 0.8 0.3
Allergy or Eczema 0.3 0.7 2.8 0.4 -0.3 0.9 0.7 0.9 0.8 0.1 0.8 0.6 1.7 1.1 0.6 0.7 0.5 -0.8 1.5 0.6 0.6 0.7 0.9 1.1
Cardiovascular Disease 0.2 0.8 2.7 1.1 1.2 1.0 0.7 0.6 -1.6 -0.2 -0.0 -1.3 1.1 0.5 0.7 0.2 1.2 -0.8 0.1 0.9 0.5 0.7 0.1 1.5
Hypothyroidism (self reported) 0.4 0.9 4.0 0.3 0.1 1.7 0.6 0.8 0.6 -0.3 0.7 0.9 2.0 0.7 0.5 1.2 0.7 -0.5 0.5 0.5 0.7 1.1 0.4 1.7
Respiratory disease 0.1 0.2 0.7 -0.6 -0.1 -0.7 -0.6 -0.4 -0.1 0.0 -0.5 0.5 -0.3 -0.1 -0.7 -0.8 -0.4 0.8 -0.3 -0.4 -0.5 -0.6 -0.5 -0.2
Type 2 Diabetes (T2D) (2018) 0.5 0.9 4.0 1.7 2.0 0.6 0.8 1.0 -1.0 0.0 0.6 -0.8 0.5 1.2 0.9 0.8 1.1 -0.8 0.7 0.6 0.7 0.8 0.6 0.5
Lung FEV1/FVC ratio 0.1 0.7 6.0 -0.8 -0.5 1.6 -0.7 -0.5 -0.2 -2.4 -0.4 0.3 1.2 -0.4 -0.7 -0.2 -0.4 0.7 -0.2 -0.7 -0.5 0.1 -0.8 0.4
Lung FVC 0.0 0.2 1.6 0.1 0.0 1.3 0.2 -0.1 -0.2 -0.5 0.7 0.2 0.3 0.5 0.0 -0.3 0.2 -0.0 0.6 0.4 0.1 0.7 0.1 0.7
Neuroticism 1.8 4.4 10.3 2.2 2.9 2.1 2.4 1.8 -0.2 1.0 2.0 0.1 1.9 1.9 2.3 2.1 2.2 -2.3 1.9 2.2 2.1 2.4 2.1 3.2
Chronotype (morning person) 0.4 0.8 3.6 -0.7 -1.9 1.4 -0.6 -1.0 -1.6 -0.2 -0.9 -1.8 -0.2 -0.9 -0.5 -0.4 -0.4 0.3 -0.5 -0.5 -0.7 -0.0 -0.7 -0.2
Hair Pigment 0.4 12.4 22.2 4.0 4.7 1.3 3.9 4.3 2.8 3.4 4.1 2.8 2.5 2.4 3.9 4.5 3.5 -3.7 2.4 3.3 4.1 3.6 4.3 2.2
Tanning 0.1 0.9 2.9 1.5 0.2 -0.0 0.8 1.3 1.7 1.4 1.4 1.3 -0.4 0.1 1.0 0.8 0.8 -0.9 -0.1 0.6 1.2 0.1 1.2 0.3
Hand grip strength (left) 0.3 0.7 3.7 -0.3 -0.3 -1.2 -0.3 -0.7 -1.7 -0.3 -1.1 -1.9 -0.5 0.0 -0.4 -0.9 -0.1 0.2 -0.6 -0.3 -0.7 -0.9 -0.8 -1.3
Number of treatments/medications taken 0.6 1.0 2.3 1.1 1.3 0.9 1.0 0.7 -1.0 1.3 0.4 -1.0 0.6 1.1 0.9 0.2 1.1 -1.0 1.2 1.3 0.6 0.8 0.9 1.5
Average weekly spirits intake 1.1 1.4 3.9 -1.5 -1.6 -0.8 -1.4 -1.0 1.1 -1.3 -0.7 0.7 -0.4 -0.7 -1.5 -1.3 -1.4 1.5 -0.5 -1.0 -1.3 -2.0 -1.1 -0.5
Sensitivity / hurt feelings 0.3 0.6 3.1 -0.5 -0.7 0.4 -0.5 -0.7 -1.8 -0.2 -0.9 -1.7 0.0 -0.2 -0.5 -0.8 -0.4 0.5 -0.4 -0.5 -0.8 -0.2 -0.7 0.1
Frequency of depressed mood in last 2 weeks 0.3 0.4 2.2 0.6 -0.0 0.5 0.6 0.3 0.2 0.6 0.6 0.3 0.1 0.1 0.7 1.5 0.3 -0.8 0.2 -0.0 0.6 1.0 0.9 0.1
Hearing difficulty/problems: Yes 4.6 7.1 19.2 2.6 1.6 0.4 2.5 2.4 0.4 2.0 2.3 0.8 4.3 3.9 2.3 2.4 2.7 -2.6 4.4 2.9 2.3 2.0 2.4 3.9
Relative age of first facial hair 0.3 0.6 3.4 0.7 -0.4 1.0 0.5 0.1 -1.8 -1.1 -0.1 -1.4 0.9 0.3 0.5 0.4 0.7 -0.6 -0.2 0.2 0.2 1.3 0.1 0.1
Other serious medical condition/disability diagnosed by doctor 1.3 1.7 3.5 -1.5 -1.5 -0.4 -1.5 -1.3 -0.3 -0.8 -1.7 -0.6 -1.3 -1.2 -1.5 -1.9 -1.3 1.4 -0.5 -1.0 -1.5 -1.4 -1.5 -1.4
Ever used hormone-replacement therapy (HRT) 0.8 1.0 2.5 -1.3 -1.6 0.8 -1.2 -0.9 0.8 -1.1 -0.7 1.2 -0.3 -0.7 -1.3 -1.1 -1.4 1.4 -0.2 -0.8 -1.0 -0.2 -0.7 0.1
Ever had hysterectomy (womb removed) 1.4 1.5 3.2 1.0 1.8 1.3 1.1 1.2 0.5 0.9 1.1 0.8 1.5 1.6 1.0 0.7 1.2 -1.0 1.8 1.7 1.0 1.4 1.1 1.2
Systolic blood pressure, automated reading 0.3 0.8 2.0 -0.3 -0.5 -0.3 -1.1 -0.6 -0.2 -1.1 -0.9 0.1 -1.4 -1.4 -1.1 -0.9 -0.9 1.2 -0.9 -1.1 -0.9 -0.8 -1.0 -0.5
Eye problems/disorders: Diabetes related eye disease 2.2 2.4 5.2 -1.6 -1.1 -0.5 -1.7 -1.8 -1.4 -1.8 -1.5 -1.1 -1.4 -1.1 -1.8 -2.3 -1.8 1.8 -1.1 -1.1 -1.9 -1.6 -1.7 -1.4
Angina 0.1 0.1 0.4 -0.4 -0.6 0.2 -0.5 -0.4 -0.0 -0.6 -0.2 -0.0 0.1 0.3 -0.5 -0.6 -0.4 0.3 0.3 -0.2 -0.5 -0.1 -0.5 0.3
Medication for hormone replacement therapy 1.0 1.1 3.5 0.1 -0.1 1.7 0.6 0.5 1.2 0.7 0.7 1.5 1.9 0.9 0.5 0.8 0.3 -0.6 1.5 0.7 0.7 1.7 0.8 1.4
Vitamin and mineral supplements 0.3 0.4 0.8 0.7 0.8 0.6 0.7 0.4 -0.5 0.7 0.4 -0.4 0.2 0.2 0.7 0.6 0.8 -0.9 0.2 0.5 0.6 0.5 0.4 0.7
Supplements: Zinc 2.1 2.3 4.3 -1.9 -2.0 -0.7 -1.9 -1.6 0.4 -1.2 -1.5 0.3 -0.8 -1.2 -2.0 -1.5 -2.1 2.0 -1.4 -1.9 -1.8 -1.4 -1.5 -1.1
Medication: Co-codamol 1.3 1.5 4.2 1.0 1.4 2.0 1.3 1.4 0.1 1.6 1.2 0.6 0.6 0.6 1.4 1.3 1.1 -1.1 0.7 1.3 1.4 1.6 1.4 0.5
Medication: Metformin 0.2 0.3 1.6 0.3 1.1 1.0 0.0 0.3 -0.2 -0.0 0.1 -0.3 0.1 1.3 -0.1 -0.2 0.2 0.1 1.1 0.5 -0.2 -0.3 -0.0 0.3
Diabetes (father) 0.3 0.4 2.6 -0.7 -0.2 -0.4 -0.5 -0.7 -0.1 -1.6 -0.3 0.0 -1.1 -0.5 -0.7 -0.5 -0.9 0.6 -0.2 -0.6 -0.7 0.0 -0.3 -0.3
Diabetes (mother) 0.1 0.2 1.0 0.4 0.6 -1.0 0.1 -0.1 -0.6 -0.9 -0.3 -0.6 -0.6 -0.1 0.1 -0.1 0.0 -0.2 -0.4 0.4 -0.1 0.1 0.1 -0.1
Severe depression (siblings) 0.3 0.3 1.2 0.5 1.1 0.1 0.6 0.6 0.4 -0.2 0.7 0.7 0.4 -0.1 0.6 0.6 0.6 -0.3 0.2 0.7 0.8 0.5 0.6 0.6
Pack years adult smoking proportion 1.4 2.1 5.2 -1.2 -1.4 -2.0 -1.8 -0.9 2.3 -0.7 -0.5 1.4 -1.4 -1.8 -1.6 -0.8 -1.6 1.6 -1.7 -1.6 -1.1 -1.9 -1.4 -0.1
Impedance of leg (right) 0.2 1.0 4.6 -0.9 -2.1 0.7 -0.9 -0.3 1.5 -0.2 -0.3 0.9 -1.0 -1.3 -0.7 -0.4 -0.9 0.7 -1.3 -1.0 -0.5 -0.1 -0.6 -1.5
Leg fat-free mass (left) 0.1 0.5 3.1 0.6 0.8 -0.3 0.3 -0.1 -1.8 -0.5 -0.4 -1.3 1.3 0.9 0.3 0.2 0.6 -0.5 0.6 0.3 0.1 0.0 -0.1 0.7
Trunk fat percentage 2.4 9.5 14.2 -3.7 -3.6 -2.3 -3.7 -3.0 1.6 -3.3 -2.4 1.2 -2.6 -2.5 -3.8 -2.8 -3.6 3.7 -3.1 -3.3 -3.1 -3.4 -3.5 -2.8
Hand grip strength (right) 0.4 1.0 5.3 -0.4 -0.4 -1.5 -0.2 -0.9 -2.2 -0.5 -1.3 -2.3 -0.2 0.3 -0.3 -0.9 -0.0 -0.1 -0.6 -0.3 -0.7 -0.7 -0.7 -1.2
Townsend deprivation index at recruitment 0.9 1.3 2.9 1.2 1.7 1.1 1.3 1.4 0.1 1.7 0.8 0.4 0.9 0.2 1.4 1.6 1.2 -1.2 0.2 0.8 1.3 1.4 1.1 0.6
Current tobacco smoking 0.5 0.7 5.4 0.7 -0.7 -1.2 -0.0 0.8 2.3 0.9 1.0 1.3 -0.7 -1.1 0.3 0.7 -0.1 -0.4 -0.8 -0.2 0.5 -0.3 0.5 -0.3
Average weekly fortified wine intake 0.7 0.8 2.1 -0.6 -0.7 -1.4 -1.0 -0.8 0.6 -0.2 -0.7 0.2 -1.0 -0.8 -1.1 -1.1 -0.9 1.1 -1.0 -1.1 -0.9 -1.4 -0.9 -0.7
Maternal smoking around birth 0.8 1.1 2.8 -0.3 -1.1 -1.1 -1.1 -0.8 0.1 -0.8 -0.7 0.1 -1.5 -1.5 -1.0 -0.8 -0.9 0.9 -1.5 -1.2 -0.9 -1.2 -0.9 -1.7
Fed-up feelings 0.1 0.1 0.8 -0.1 0.3 0.4 -0.1 -0.4 0.0 0.4 -0.1 -0.4 -0.0 0.1 -0.1 0.3 -0.3 0.1 -0.4 -0.4 -0.2 0.6 -0.3 0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.4 0.5 1.8 1.1 0.8 0.4 0.8 0.5 0.1 1.0 0.9 0.1 0.2 0.3 0.8 1.3 0.7 -1.0 0.2 0.6 0.8 1.0 0.7 0.3
Relative age voice broke 1.8 2.8 10.0 -1.7 -1.6 1.1 -1.4 -1.9 -2.6 -3.2 -1.8 -2.2 -0.9 -1.0 -1.5 -1.6 -1.3 1.4 -1.4 -1.1 -1.8 -0.3 -1.8 -1.3
Taking other prescription medications 0.4 0.6 2.1 0.8 1.5 -0.0 0.8 0.5 -0.9 1.2 0.4 -0.9 0.2 0.9 0.7 0.3 0.8 -0.8 0.9 1.0 0.5 0.0 0.5 0.6
Age when periods started (menarche) 1.2 2.9 4.8 -2.2 -1.3 -0.0 -1.7 -1.8 -1.6 -2.0 -2.2 -1.7 -1.4 -1.0 -1.8 -2.1 -1.7 1.9 -1.5 -1.6 -1.9 -1.0 -2.1 -1.8
Bilateral oophorectomy (both ovaries removed) 0.9 1.0 7.7 0.2 0.4 0.8 0.3 1.2 2.8 0.8 0.8 2.5 0.7 0.2 0.3 0.7 0.2 -0.1 0.4 0.4 0.7 1.0 0.8 0.4
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.7 3.2 -0.6 -0.5 -1.3 -0.9 -0.5 0.1 -1.8 -0.6 -0.1 -0.6 -0.4 -0.9 -0.8 -0.9 0.9 -0.4 -0.8 -0.9 -1.3 -0.7 -0.3
Tinnitus: Yes, but not now, but have in the past 1.1 1.1 4.5 -0.9 -0.9 -1.6 -0.9 -0.5 -0.2 -0.3 -1.0 -0.5 -1.4 -1.2 -0.9 -1.1 -1.1 0.9 -1.4 -0.8 -1.0 -1.3 -0.7 -2.1
Qualifications: CSEs or equivalent 0.2 0.3 0.8 -0.5 -0.1 0.9 -0.5 -0.5 -0.7 -0.9 -0.3 -0.5 -0.3 -0.7 -0.4 -0.4 -0.5 0.3 -0.9 -0.2 -0.5 -0.0 -0.6 -0.0
Serious illness, injury or assault to yourself 0.2 0.3 1.7 0.4 0.1 -0.2 0.3 0.4 -1.3 0.9 -0.4 -1.1 0.5 0.2 0.3 -0.0 0.5 -0.3 0.3 0.5 0.1 0.1 -0.0 0.6
High blood pressure 0.2 0.7 3.0 1.0 1.2 0.4 0.7 0.8 -1.7 0.4 -0.2 -1.1 0.9 0.6 0.7 0.0 1.1 -0.7 0.3 1.0 0.5 0.7 0.2 0.7
Hayfever, allergic rhinitis or eczema 0.1 0.2 1.0 0.1 -0.5 0.8 0.4 0.4 0.1 -0.3 0.2 -0.2 1.0 0.3 0.4 0.4 0.1 -0.6 1.0 0.2 0.2 0.4 0.5 0.2
Multivitamins +/- minerals 0.3 0.4 0.9 -0.5 -0.6 -0.8 -0.8 -0.4 0.5 -0.7 -0.6 0.8 -0.4 -0.2 -0.9 -0.8 -0.7 1.0 -0.0 -0.6 -0.6 -0.6 -0.5 -0.1
Stomach or abdominal pain in last month 0.3 0.3 1.2 -0.4 -0.5 -0.2 -0.4 -0.6 -0.3 -0.6 -0.5 -0.3 -1.1 -0.6 -0.3 -0.0 -0.5 0.4 -1.1 -0.9 -0.4 0.0 -0.3 -0.8
Supplements: Glucosamine 2.0 2.6 4.4 -1.7 -2.0 -0.5 -1.5 -2.1 -1.7 -1.9 -2.0 -1.8 -1.2 -1.1 -1.5 -1.7 -1.8 1.6 -1.2 -1.4 -1.9 -1.4 -1.7 -1.6
Diverticular disease/diverticulitis (self-reported) 0.2 0.3 0.9 -0.8 -0.6 -0.2 -0.4 -0.6 -0.4 1.0 -0.7 -0.4 0.2 -0.7 -0.4 -0.4 -0.5 0.3 -0.6 -0.5 -0.4 -0.6 -0.5 -0.3
Medication: Atenolol 1.9 2.4 4.9 1.6 1.2 -0.2 1.7 1.2 0.3 0.9 1.7 0.3 2.0 1.7 1.7 1.1 1.8 -1.9 1.5 1.9 1.6 1.9 1.7 2.2
Medication: Levothyroxine sodium 0.2 0.4 1.8 -0.8 -1.0 0.2 -0.6 -0.5 -0.3 -1.3 -0.4 -0.4 0.4 -0.4 -0.6 -0.2 -0.4 0.5 -0.6 -0.5 -0.6 -0.6 -0.9 0.2
Sitting height 0.6 4.3 8.9 2.5 1.3 3.0 2.2 2.3 -0.3 2.2 1.5 0.6 2.5 1.3 2.4 2.4 2.3 -2.4 2.2 1.5 2.3 2.4 2.2 1.7
Chronic bronchitis/emphysema (father) 0.4 0.4 5.9 0.1 0.2 -2.4 -0.3 -0.3 0.4 -0.1 -0.1 0.2 -0.9 -0.2 -0.3 -0.2 -0.2 0.3 -0.7 -0.4 -0.2 -0.8 -0.2 -0.3
High blood pressure (mother) 0.3 0.4 1.8 0.6 1.4 0.7 0.5 0.5 -1.0 -0.4 -0.3 -1.2 -0.0 0.9 0.4 0.0 0.7 -0.2 0.7 0.5 0.2 0.2 0.1 -0.2
Body mass index (BMI) 0.8 3.3 7.9 -1.7 -1.5 -2.1 -2.1 -2.0 0.0 -2.8 -1.6 -0.1 -1.5 -1.1 -2.2 -1.7 -2.0 2.2 -1.4 -1.8 -2.0 -2.5 -2.0 -1.3
Impedance of leg (left) 0.2 1.1 4.6 -1.0 -2.1 0.8 -0.9 -0.1 1.9 0.1 0.0 1.4 -1.0 -1.4 -0.7 -0.2 -0.9 0.8 -1.3 -1.1 -0.4 -0.2 -0.5 -1.2
Leg predicted mass (left) 0.1 0.6 3.5 0.7 0.8 -0.4 0.4 -0.0 -1.9 -0.4 -0.4 -1.4 1.3 0.9 0.3 0.2 0.7 -0.6 0.6 0.4 0.1 0.1 -0.1 0.8
Trunk fat mass 1.2 5.2 7.9 -2.5 -2.6 -2.0 -2.8 -2.3 0.9 -2.7 -1.9 0.7 -1.7 -1.7 -2.8 -2.0 -2.6 2.8 -2.3 -2.5 -2.3 -2.7 -2.7 -1.9
Waist circumference 0.5 1.9 4.8 -1.3 -1.5 -1.4 -1.7 -1.3 0.6 -2.2 -1.0 0.5 -0.7 -0.9 -1.7 -1.2 -1.5 1.6 -1.1 -1.3 -1.4 -1.6 -1.6 -0.9
Number of incorrect matches in round 0.9 1.5 3.4 1.2 1.9 -0.5 1.2 1.4 1.3 1.7 1.4 1.3 -0.5 1.0 1.2 1.5 1.3 -0.9 0.5 0.6 1.4 1.4 1.3 1.4
Past tobacco smoking 0.1 0.2 1.1 0.1 0.4 1.1 0.4 0.0 -0.0 -0.2 0.4 0.2 0.5 0.5 0.3 0.7 0.1 -0.3 0.3 0.2 0.3 0.7 0.4 0.3
Alcohol usually taken with meals 1.5 2.5 10.8 0.4 1.2 1.1 0.9 1.6 2.8 1.6 2.0 3.3 1.2 1.5 0.9 1.9 0.8 -0.5 2.2 0.7 1.5 0.2 1.4 1.1
Nervous feelings 2.0 3.7 6.9 2.1 2.6 2.0 2.2 1.8 -0.2 0.7 1.6 -0.2 1.4 2.4 2.1 1.6 2.2 -2.0 2.5 2.3 1.8 2.1 2.0 1.9
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 2.2 1.1 0.7 0.8 1.1 0.8 0.2 0.7 0.8 0.0 0.5 0.3 1.2 1.3 0.8 -1.3 0.7 0.8 1.0 1.5 1.1 0.4
Hearing difficulty/problems with background noise 0.9 1.5 6.1 0.7 0.5 1.4 0.8 0.7 0.6 0.4 1.0 1.2 2.4 1.5 0.7 1.1 0.7 -0.7 2.5 1.0 0.8 1.3 0.8 2.0
Hair/balding pattern: Pattern 2 0.5 0.6 3.6 0.7 -0.3 0.2 0.5 0.9 0.9 -0.0 1.1 0.8 0.8 0.5 0.6 1.0 0.6 -0.7 0.7 0.4 0.7 0.4 0.7 1.9
Had menopause 0.1 0.1 0.7 -0.4 0.0 0.8 -0.2 0.0 0.1 -0.1 -0.2 0.5 -0.1 -0.3 -0.2 -0.3 -0.0 0.1 0.8 -0.3 -0.1 0.4 -0.2 -0.2
Had other major operations 0.1 0.1 0.7 0.0 0.5 0.4 -0.2 0.1 0.8 0.2 0.2 0.8 0.3 0.1 -0.2 0.3 -0.3 0.2 0.4 0.1 0.0 0.2 -0.0 0.3
Forced vital capacity (FVC) 0.7 2.7 5.2 2.0 0.9 2.1 1.8 1.6 -0.7 1.8 1.3 -0.1 1.9 0.9 1.9 1.6 2.0 -2.1 1.2 1.5 1.8 2.3 1.7 1.2
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.8 4.7 -1.1 -1.4 -1.5 -1.5 -1.1 0.4 -2.2 -1.0 -0.1 -1.5 -1.2 -1.5 -1.5 -1.5 1.5 -1.4 -1.2 -1.4 -1.6 -1.2 -1.2
Ever unenthusiastic/disinterested for a whole week 0.2 0.3 1.4 0.9 0.3 0.1 0.5 0.7 -0.1 1.2 0.4 -0.2 0.2 0.1 0.6 0.5 0.6 -0.9 0.0 0.6 0.6 0.5 0.6 0.3
Qualifications: None of the above 0.2 0.4 1.1 -0.9 -0.1 0.0 -0.5 -0.5 1.1 0.6 -0.4 0.8 -1.0 -1.0 -0.5 -0.2 -0.7 0.6 -1.0 -0.8 -0.3 0.3 -0.4 -0.2
Financial difficulties in last 2 years 1.7 2.2 5.6 1.4 0.9 -1.0 1.4 1.6 2.4 1.7 2.0 2.4 1.1 0.5 1.5 1.9 1.1 -1.5 0.4 1.4 1.8 0.9 1.8 0.7
Mouth/teeth dental problems 0.2 0.3 1.9 -0.1 0.7 0.5 0.4 0.1 0.0 -0.4 0.5 0.6 1.4 0.6 0.3 0.6 0.4 -0.3 0.9 0.2 0.4 0.5 0.3 1.0
Heart attack 0.2 0.2 1.3 0.4 -0.2 0.4 0.1 0.4 0.4 0.4 0.5 0.4 1.2 0.9 0.2 -0.0 0.3 -0.3 0.7 0.5 0.3 0.4 0.3 0.4
Allergy 0.0 0.1 0.7 0.0 0.2 -0.2 -0.2 -0.2 -0.4 -0.0 -0.1 -0.4 -0.4 -0.2 -0.1 -0.1 -0.0 0.4 -0.8 -0.1 -0.1 -0.2 -0.4 0.0
Pain all over the body in last month 0.3 0.3 2.2 0.1 0.2 -0.7 0.1 0.3 1.5 -0.5 0.8 1.5 -0.2 -0.3 0.1 0.5 -0.2 0.0 -0.5 0.2 0.3 0.2 0.5 0.3
Diabetes (self-reported) 0.2 0.3 0.8 0.0 0.4 0.2 -0.5 -0.3 -0.9 -0.7 -0.4 -0.8 -0.7 0.4 -0.5 -0.5 -0.3 0.5 0.2 -0.4 -0.6 -0.5 -0.6 -0.6
Hayfever/allergic rhinitis (self-reported) 0.1 0.1 0.6 -0.0 0.1 0.4 0.2 0.2 -0.4 -0.3 0.0 -0.2 0.5 0.3 0.1 -0.0 0.1 -0.1 0.8 0.6 0.0 -0.1 0.1 0.1
Medication: Ramipril 1.0 1.3 2.7 1.2 1.5 0.8 1.0 1.3 1.2 1.6 1.0 1.4 1.4 1.1 0.9 0.9 0.9 -0.9 0.9 1.3 1.0 0.7 1.2 0.9
Medication: Simvastatin 0.2 0.2 1.2 -0.2 1.1 0.5 0.2 0.4 1.0 0.6 0.3 0.8 0.2 0.6 0.1 -0.0 0.1 -0.1 0.5 0.5 0.3 0.3 0.1 0.4
Fluid intelligence score 1.4 2.8 6.1 2.0 1.4 0.8 1.8 1.3 -2.4 1.3 0.9 -1.8 2.5 1.4 1.9 0.9 2.0 -2.3 1.2 2.3 1.4 1.4 1.4 1.3
Illnesses of siblings 0.5 0.7 2.7 0.5 0.0 1.6 0.8 0.6 -0.5 0.6 0.5 -0.3 1.6 0.9 0.8 0.4 1.0 -1.0 0.8 0.9 0.7 1.0 0.7 0.9
Neuroticism score 0.9 2.0 3.9 1.6 2.0 1.5 1.6 1.2 -0.7 0.7 1.0 -0.7 1.0 1.5 1.6 1.2 1.5 -1.5 1.4 1.6 1.2 1.7 1.4 1.8
Weight 0.2 0.9 3.1 -0.7 -0.9 -0.9 -1.1 -1.0 -0.5 -1.8 -1.0 -0.2 -0.1 -0.3 -1.1 -0.7 -0.8 1.1 -0.6 -1.1 -1.0 -1.2 -1.3 -0.5
Impedance of arm (right) 1.1 5.1 10.7 -3.2 -3.3 0.9 -2.4 -1.6 3.3 -0.6 -1.2 2.5 -2.2 -2.4 -2.3 -1.5 -2.7 2.3 -2.3 -2.2 -1.5 -1.1 -2.0 -3.1
Arm fat percentage (right) 2.5 9.7 14.5 -3.6 -3.6 -2.0 -3.8 -3.3 1.4 -3.8 -2.6 0.9 -2.7 -2.5 -3.8 -3.0 -3.7 3.7 -2.7 -3.1 -3.2 -3.5 -3.5 -2.8
Trunk fat-free mass 0.6 3.2 6.2 2.4 1.9 0.7 1.8 1.3 -2.5 0.5 0.7 -1.7 2.5 2.1 1.9 1.6 2.2 -2.0 2.0 1.5 1.4 1.4 1.4 2.2
Hip circumference 0.8 3.6 9.1 -1.9 -2.4 -0.8 -2.4 -2.3 0.0 -3.0 -1.7 0.0 -1.1 -1.3 -2.4 -1.7 -2.1 2.4 -1.2 -2.1 -2.1 -2.3 -2.3 -1.0
Time employed in main current job 0.5 0.5 1.3 1.0 0.0 0.3 0.8 0.6 -0.1 0.9 0.5 -0.3 1.1 0.6 0.7 0.6 0.7 -1.1 0.9 0.9 0.6 0.9 0.7 0.5
Alcohol intake versus 10 years previously 0.1 0.2 0.8 -0.5 0.5 0.6 -0.3 -0.2 -0.9 -0.6 -0.7 -0.4 -0.4 0.0 -0.3 -0.3 -0.2 0.2 -0.2 -0.1 -0.3 0.3 -0.6 -0.9
Father’s age at death 0.7 1.0 2.4 0.8 1.0 1.0 0.9 0.8 -0.8 1.1 0.1 -0.7 1.6 1.4 0.8 0.7 1.1 -0.7 1.0 1.0 0.7 1.5 0.5 1.5
Worrier / anxious feelings 0.5 0.9 3.2 1.2 1.2 0.5 1.1 0.7 -1.6 0.6 0.1 -1.8 0.3 0.3 1.2 0.6 1.1 -1.3 -0.3 1.1 0.7 1.1 0.6 0.7
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 1.3 1.1 0.7 -0.4 0.6 0.6 -1.1 0.7 0.4 -1.1 0.4 0.3 0.7 0.8 0.6 -0.9 -0.5 0.6 0.4 0.9 0.3 -0.1
Falls in the last year 0.8 1.1 2.4 -0.4 -1.3 -0.5 -1.2 -1.1 0.0 -1.1 -0.9 -0.4 -1.5 -1.4 -1.1 -1.3 -0.9 1.0 -0.5 -0.9 -1.1 -1.4 -1.0 -1.1
Hair/balding pattern: Pattern 3 0.3 0.5 1.0 0.6 1.0 0.1 0.8 0.9 0.8 0.8 0.6 1.0 0.5 0.4 0.6 0.8 0.8 -0.4 0.0 0.2 0.8 0.7 0.7 -0.2
Number of live births 0.4 0.6 1.3 0.9 0.9 0.6 0.8 0.9 0.6 0.1 0.6 0.6 0.9 1.1 0.7 1.0 0.6 -0.6 1.0 0.5 0.7 1.1 0.9 0.4
Forced expiratory volume in 1-second (FEV1) 0.5 1.5 4.6 1.5 0.7 2.1 1.4 1.1 -1.0 0.4 0.9 -0.3 1.8 0.5 1.4 1.2 1.5 -1.5 0.8 0.9 1.3 1.8 1.2 0.8
Pulse rate 0.2 0.3 2.0 -0.4 -0.4 0.5 -0.2 -0.1 0.2 0.6 -0.5 -0.2 -0.3 -0.8 -0.2 -0.2 -0.4 0.4 -1.1 -0.3 -0.2 -0.4 -0.2 -1.4
Happiness 1.7 2.1 4.2 1.6 1.6 0.7 1.4 1.5 1.1 0.4 1.7 1.1 1.8 2.0 1.3 1.5 1.2 -1.3 2.1 1.7 1.3 1.4 1.5 1.0
Noisy workplace 1.5 1.9 3.5 -1.1 -1.2 -1.1 -1.5 -1.5 -1.5 -1.9 -1.5 -1.5 -1.5 -0.9 -1.5 -1.6 -1.4 1.4 -0.8 -1.4 -1.7 -1.1 -1.5 -1.0
Qualifications: A levels/AS levels or equivalent 2.3 5.2 10.7 2.4 1.9 2.0 2.6 1.9 -1.2 2.1 1.7 -0.4 3.3 2.4 2.6 1.8 2.5 -2.9 2.6 2.6 2.3 2.4 2.3 2.5
Serious illness, injury or assault of a close relative in last 2 years 1.2 1.4 3.5 1.4 1.8 -0.7 1.4 0.9 -1.9 0.5 0.6 -1.5 1.3 1.3 1.3 0.7 1.7 -1.3 1.2 1.2 1.0 0.1 0.7 0.6
Mouth/teeth dental problems: Dentures 0.4 0.6 1.8 -0.3 -0.8 -0.6 -0.9 -0.4 1.3 0.5 -0.3 0.6 -1.3 -0.3 -0.9 -0.7 -0.8 0.9 -0.8 -0.7 -0.7 -1.0 -0.6 -1.4
Asthma 0.1 0.3 1.0 -0.0 -0.2 -1.0 -0.3 -0.6 -0.4 0.8 -0.4 -0.2 -1.0 -0.6 -0.3 -0.6 -0.3 0.2 -0.7 -0.3 -0.3 -0.1 -0.2 -0.9
Medication: Ibuprofen (e.g. Nurofen) 0.8 1.0 3.4 1.2 0.2 1.2 0.8 0.3 -1.8 0.5 0.2 -1.6 1.1 0.8 0.8 0.3 0.8 -1.0 1.6 1.4 0.3 0.7 0.7 1.3
Medication: Cholesterol lowering 0.1 0.2 1.1 -0.3 0.8 -1.0 -0.1 -0.3 0.1 -0.6 -0.3 -0.2 -0.8 0.2 -0.2 -0.6 -0.2 0.3 -0.5 -0.1 -0.3 -0.2 -0.3 -0.1
Depression (self-reported) 0.7 0.8 2.6 0.9 1.0 0.3 0.7 0.7 1.2 -0.7 1.6 1.5 0.9 0.4 0.7 0.8 0.8 -0.6 0.3 0.7 0.9 0.8 0.8 1.3
Medication: Lansoprazole 0.7 0.8 3.1 -0.7 -0.8 -1.6 -0.7 -0.4 0.5 0.3 -0.8 -0.3 -1.1 -0.9 -0.7 -0.7 -0.8 0.6 -1.1 -0.7 -0.7 -1.1 -0.7 -1.8
Prospective memory result 1.5 1.9 4.6 -1.4 -1.4 -1.9 -1.5 -1.2 0.2 -0.2 -1.2 0.1 -2.1 -0.8 -1.6 -1.3 -1.3 1.7 -1.0 -1.4 -1.4 -2.1 -1.4 -1.2
Lung cancer (father) 1.8 2.1 6.4 -1.3 -0.9 -1.1 -1.3 -0.9 -0.0 -1.4 -1.0 -0.2 -2.3 -1.6 -1.3 -1.1 -1.2 1.2 -2.3 -1.9 -1.1 -1.6 -1.3 -2.5
Illnesses of mother 0.9 1.1 3.0 -1.4 -1.7 -0.5 -1.1 -1.3 1.0 -0.6 -0.3 0.8 -0.5 -1.5 -1.1 -0.5 -1.4 1.0 -1.7 -1.4 -0.8 -0.6 -0.8 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 1.8 4.1 1.7 0.8 1.6 1.5 1.2 -1.2 -0.1 1.1 -0.7 2.0 1.0 1.5 1.2 1.9 -1.6 1.2 1.2 1.3 1.8 1.1 1.2
Pulse wave Arterial Stiffness index 1.5 1.7 3.8 1.9 0.9 0.9 1.5 1.5 -0.8 1.1 1.2 -0.4 1.1 1.2 1.6 1.4 1.7 -1.8 1.8 1.3 1.4 1.0 1.3 0.5
Impedance of arm (left) 1.7 7.7 16.1 -4.0 -3.6 0.3 -3.1 -2.2 3.3 -1.4 -1.7 2.5 -2.8 -2.9 -3.1 -2.3 -3.4 3.1 -2.9 -2.8 -2.2 -1.9 -2.7 -3.4
Arm fat mass (right) 1.4 5.8 10.4 -2.5 -2.6 -2.1 -2.9 -2.6 0.5 -3.2 -2.1 0.3 -1.9 -1.7 -2.9 -2.3 -2.7 2.9 -2.2 -2.5 -2.6 -2.8 -2.8 -1.9
Trunk predicted mass 0.5 3.1 6.2 2.4 1.9 0.6 1.8 1.3 -2.5 0.5 0.7 -1.6 2.5 2.1 1.8 1.5 2.1 -2.0 2.0 1.5 1.4 1.4 1.4 2.2
Standing height 0.4 3.9 7.9 2.2 1.2 2.5 2.0 2.2 -0.8 2.0 1.3 0.2 2.8 2.0 2.1 2.2 2.5 -2.3 1.6 1.3 2.1 2.6 1.6 1.7
Length of working week for main job 2.7 3.0 8.4 -2.0 -1.2 -2.0 -2.0 -1.5 0.5 -1.1 -1.5 0.1 -1.0 -1.7 -2.1 -1.7 -1.9 2.3 -1.5 -1.9 -1.9 -2.9 -2.0 -1.2
Exposure to tobacco smoke at home 2.5 2.8 7.6 -1.2 -1.2 -1.0 -1.3 -1.8 -2.7 -1.6 -2.2 -2.8 -1.4 -1.9 -1.3 -1.2 -1.2 1.0 -2.0 -1.9 -1.6 -1.2 -1.8 -1.5
Breastfed as a baby 2.2 2.8 5.1 2.1 1.8 0.1 1.9 1.6 -1.8 1.8 0.8 -1.2 2.3 2.1 1.8 1.4 2.2 -1.7 1.2 1.5 1.4 1.4 1.4 1.8
Tense / ‘highly strung’ 0.3 0.5 3.0 0.7 0.6 0.4 0.5 0.7 -0.0 0.8 0.5 0.2 0.7 0.5 0.5 0.7 0.4 -0.3 1.2 0.6 0.4 0.6 0.6 1.7
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 1.1 1.1 0.7 -0.4 0.9 0.8 0.1 0.1 0.9 0.3 0.6 0.2 1.0 0.7 0.8 -1.0 -0.2 0.7 0.9 1.1 0.9 0.1
Hair/balding pattern: Pattern 4 0.1 0.3 1.4 -0.3 -0.0 1.2 -0.2 0.1 0.8 0.1 0.2 1.1 -0.4 -0.6 -0.1 -0.3 -0.2 0.3 -0.7 0.1 0.2 0.2 0.0 -0.7
Birth weight of first child 0.2 0.3 1.3 -0.1 -1.1 -0.2 -0.2 -0.5 -1.0 -0.2 -0.6 -1.1 -0.6 -0.5 -0.1 -0.3 -0.2 -0.1 -0.9 -0.3 -0.4 0.4 -0.2 -0.8
Peak expiratory flow (PEF) 0.1 0.1 0.7 0.2 -0.8 0.2 -0.0 -0.1 -0.3 -0.1 -0.2 -0.1 0.3 -0.7 0.1 0.1 0.1 -0.3 -0.6 -0.4 0.1 0.4 -0.0 -0.4
Pulse wave reflection index 1.3 1.6 3.4 1.5 1.0 0.1 1.4 1.2 -0.4 1.0 1.1 -0.1 1.7 1.3 1.4 1.0 1.4 -1.8 1.5 1.3 1.2 1.3 1.3 1.5
Ever highly irritable/argumentative for 2 days 1.3 1.6 2.9 1.4 0.5 1.6 1.1 1.4 1.2 1.0 1.4 1.0 1.6 1.2 1.1 1.7 1.1 -1.3 0.9 1.4 1.3 1.5 1.1 1.0
Loud music exposure frequency 0.7 0.8 2.1 -0.7 -1.3 -0.8 -0.8 -0.8 -0.2 -0.1 -0.8 -0.4 -1.0 -1.3 -0.6 -0.5 -0.8 0.5 -1.4 -1.1 -0.7 -0.7 -0.7 -1.5
Qualifications: O levels/GCSEs or equivalent 1.5 2.4 5.1 1.6 0.7 1.1 1.8 1.2 -1.0 1.0 0.8 -0.8 2.0 2.3 1.7 1.0 1.8 -2.1 2.1 2.0 1.4 1.9 1.5 1.0
Mouth/teeth dental problems: Bleeding gums 1.1 1.4 4.8 -0.7 -1.2 -0.0 -1.0 -1.1 -1.4 -0.8 -1.4 -1.4 -1.4 -1.9 -0.8 -0.6 -0.9 0.9 -2.2 -1.2 -1.0 -0.8 -1.2 -1.2
Blood clot in the leg (DVT) 0.4 0.5 1.4 0.8 0.5 1.2 0.6 0.7 0.4 -0.2 0.8 0.4 0.6 0.7 0.6 0.9 0.8 -0.8 0.7 0.3 0.7 0.7 0.5 0.9
Medication: Paracetamol 0.1 0.1 0.4 -0.0 -0.5 0.1 -0.2 -0.2 -0.1 -0.5 0.0 -0.6 0.2 -0.6 -0.1 0.0 -0.5 -0.1 -0.0 -0.1 -0.4 0.2 0.1 0.2
Headache pain in last month 0.4 0.7 4.3 -0.3 0.8 1.2 0.1 -0.2 -2.1 -0.2 -0.8 -1.7 0.9 1.5 -0.0 -0.1 0.1 -0.1 1.1 0.5 -0.4 0.1 -0.3 0.3
Medication for cholesterol, blood pressure or diabetes 0.2 0.3 1.0 -0.1 -0.3 1.0 0.2 0.4 0.9 0.7 0.6 0.9 0.9 0.2 0.3 0.6 0.0 -0.2 0.8 0.2 0.4 0.6 0.5 0.1
Glaucoma (self-reported) 0.1 0.1 0.4 -0.3 0.6 0.1 -0.0 -0.5 -0.2 0.2 -0.2 -0.4 -0.1 0.0 -0.2 -0.7 -0.1 0.3 0.2 -0.0 -0.2 -0.0 -0.3 -0.1
Gout (self-reported) 0.3 0.4 0.9 -0.3 -0.7 -0.9 -0.6 -0.7 -0.9 -0.8 -0.7 -0.8 -0.3 -0.1 -0.7 -0.9 -0.6 0.8 -0.5 -0.2 -0.9 -0.5 -0.6 -0.1
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 1.3 -0.5 -0.4 1.2 -0.2 -0.0 -0.4 -0.8 -0.1 -0.0 1.0 -0.1 -0.2 0.2 -0.1 0.1 -0.1 -0.1 -0.2 0.1 -0.4 0.7
Medication: Amlodipine 0.6 0.8 1.9 -0.7 -0.7 -1.4 -0.9 -1.1 -0.8 -1.3 -1.2 -0.8 -0.3 -0.8 -0.9 -1.0 -0.9 0.7 -0.9 -0.3 -1.1 -0.6 -1.0 -0.0
Medication: Ventolin 100micrograms inhaler 1.0 1.2 3.5 -0.9 -1.1 -0.6 -1.4 -0.8 -0.2 -0.6 -0.9 0.3 -1.0 -1.9 -1.3 -1.0 -1.2 1.4 -1.6 -1.5 -1.1 -1.4 -1.2 -0.1
Birth weight 1.1 2.5 4.3 1.7 1.2 0.9 1.8 1.4 0.4 1.5 1.5 0.6 1.9 2.0 1.8 1.6 1.6 -1.9 1.4 1.7 1.7 2.1 1.7 1.3
Chronic bronchitis/emphysema (mother) 1.9 2.2 4.9 2.2 1.7 -0.2 1.9 1.5 -1.2 1.5 0.8 -0.9 1.2 1.1 1.9 1.4 2.0 -2.0 0.9 1.5 1.6 1.5 1.6 1.2
High blood pressure (siblings) 0.2 0.2 1.1 0.2 0.4 -0.6 -0.0 -0.3 -1.1 -0.7 -0.6 -1.0 -0.6 0.2 -0.1 -0.2 -0.2 0.0 -0.1 -0.1 -0.4 0.3 -0.2 -0.5
Forced vital capacity (FVC), Best measure 0.6 2.3 4.3 2.0 1.0 1.1 1.7 1.3 -1.6 0.8 1.1 -1.1 2.0 1.3 1.7 1.2 2.1 -2.0 1.4 1.5 1.4 2.1 1.3 1.1
Body fat percentage 2.3 9.0 13.5 -3.5 -3.5 -2.2 -3.7 -3.0 1.5 -3.4 -2.3 1.1 -2.6 -2.5 -3.7 -2.7 -3.5 3.6 -3.0 -3.2 -3.1 -3.4 -3.4 -2.7
Leg fat percentage (right) 1.5 5.5 10.1 -2.3 -2.7 -1.8 -2.9 -2.4 1.2 -3.2 -1.8 0.7 -2.0 -2.0 -2.9 -2.2 -2.7 2.8 -2.1 -2.4 -2.4 -2.9 -2.6 -1.8
Arm fat-free mass (right) 0.5 2.6 5.6 2.1 1.9 0.1 1.6 1.2 -2.3 0.1 0.7 -1.5 2.4 1.8 1.6 1.3 1.9 -1.7 1.6 1.4 1.2 1.2 1.1 2.4
Exposure to tobacco smoke outside home 1.0 1.3 2.4 1.5 0.9 0.5 1.1 1.3 1.2 1.5 1.5 1.3 1.1 0.3 1.2 1.3 1.1 -1.1 0.3 1.2 1.4 0.8 1.3 1.2
Comparative body size at age 10 0.5 1.4 2.9 1.4 1.7 0.2 1.3 0.9 0.4 0.3 1.2 0.9 1.1 1.1 1.3 1.2 1.3 -1.3 1.3 1.4 1.4 0.9 1.3 1.2
Number of full brothers 1.4 1.8 6.5 1.4 1.8 0.9 1.3 1.3 0.7 0.5 1.4 0.7 0.7 1.8 1.2 1.4 1.4 -1.0 2.5 1.0 1.3 1.5 1.2 1.0
Worry too long after embarrassment 0.0 0.1 0.6 -0.2 0.2 0.8 0.0 -0.1 0.1 -0.4 0.3 0.1 -0.3 -0.3 -0.0 0.1 -0.1 0.2 -0.3 -0.3 -0.0 -0.0 0.0 0.2
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 1.7 0.6 0.2 0.1 0.4 0.3 -1.3 -1.0 0.1 -0.9 0.3 -0.3 0.4 0.6 0.5 -0.6 -0.1 0.2 0.2 0.4 0.2 0.1
Wheeze or whistling in the chest in last year 0.5 0.9 2.5 1.3 0.5 0.1 1.0 1.1 -0.1 1.6 0.7 0.2 0.8 0.7 1.1 1.0 1.1 -1.2 0.3 0.9 1.0 1.3 1.0 0.4
Number of children fathered 1.2 1.3 5.7 0.6 -0.4 2.4 0.4 0.8 1.2 -0.1 1.2 1.7 2.1 1.1 0.3 0.4 0.6 -0.4 1.9 0.8 0.7 1.0 0.6 1.5
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 0.8 -0.1 -0.4 0.5 0.2 -0.1 -0.9 -0.7 -0.2 -0.9 0.1 0.2 0.2 -0.2 0.4 -0.3 0.4 0.6 0.1 0.8 -0.1 -0.1
Age at first live birth 0.1 0.2 0.7 0.2 0.2 0.1 0.2 0.1 -0.4 -0.9 0.5 -0.3 0.2 0.6 0.2 0.2 0.4 -0.2 0.3 0.5 0.2 0.5 -0.0 0.7
Pulse wave peak to peak time 1.3 1.6 3.4 -1.8 -0.9 -0.7 -1.5 -1.3 1.1 -1.2 -1.1 0.7 -1.0 -1.1 -1.5 -1.3 -1.6 1.8 -1.6 -1.3 -1.3 -0.9 -1.3 -0.5
Health satisfaction 0.1 0.1 0.8 0.1 0.9 -0.2 0.2 0.4 0.4 0.3 0.1 0.0 -0.0 0.9 0.1 0.2 0.2 0.0 0.4 0.5 0.1 -0.0 0.0 0.5
Shortness of breath walking on level ground 1.8 2.2 4.8 1.3 1.3 1.6 1.4 1.5 0.8 1.1 1.4 1.2 1.7 2.2 1.3 1.4 1.3 -1.2 2.1 1.7 1.4 1.6 1.6 1.2
Qualifications: College or University degree 0.1 0.4 1.5 0.8 1.2 -0.5 0.7 0.1 -0.9 0.6 0.4 -0.4 0.2 0.5 0.7 0.1 0.8 -0.7 0.8 0.8 0.6 -0.4 0.6 0.2
Eye problems/disorders: None of the above 1.0 1.2 3.5 1.0 1.5 0.7 0.9 1.1 1.8 0.3 1.4 1.9 0.7 0.9 0.8 1.7 0.7 -0.6 0.6 0.4 1.1 0.5 1.2 1.0
Mouth/teeth dental problems: Loose teeth 0.3 0.4 1.1 -0.7 0.4 0.2 -0.5 -0.4 -1.1 -0.8 -0.8 -0.9 -0.4 -0.1 -0.5 -0.4 -0.5 0.5 -0.5 -0.8 -0.6 -0.0 -0.8 -0.1
Emphysema/chronic bronchitis 0.2 0.2 0.7 -0.6 -0.1 -0.5 -0.4 -0.2 0.9 0.8 -0.4 0.7 -0.1 -0.1 -0.4 -0.5 -0.5 0.2 -0.1 -0.4 -0.2 -0.6 -0.3 -0.5
Medication for pain relief, constipation, heartburn 0.6 1.0 2.9 -1.7 -0.8 0.7 -1.0 -0.9 0.2 -0.2 -1.1 0.3 -0.8 -1.2 -1.0 -0.5 -1.0 1.2 -1.5 -1.7 -0.7 -0.6 -1.2 -1.0
Neck or shoulder pain in last month 0.3 0.5 2.9 -0.6 -0.1 1.5 -0.1 0.1 1.6 0.7 0.4 1.7 -0.1 0.2 -0.2 0.5 -0.5 0.5 0.8 -0.1 0.1 0.1 0.2 0.1
Medication: Blood pressure 0.2 0.4 2.9 0.5 0.3 -0.8 -0.1 -0.1 -1.7 -0.5 -0.7 -1.6 -0.5 -0.1 -0.1 -0.8 0.3 -0.1 -0.7 0.2 -0.3 -0.4 -0.5 -0.1
Angina (self-reported) 0.1 0.1 0.4 -0.2 -0.4 0.5 -0.3 -0.3 -0.0 -0.7 -0.1 0.0 0.4 0.4 -0.3 -0.4 -0.2 0.1 0.5 0.1 -0.3 0.2 -0.2 0.5
Migraine (self-reported) 0.2 0.2 1.1 0.1 0.6 -0.6 0.4 0.5 0.2 -0.5 0.6 0.1 -0.0 -0.0 0.4 0.1 0.3 -0.3 -0.5 0.6 0.4 0.3 0.4 1.0
Medication: Ibuprofen 0.6 0.7 2.4 1.1 0.3 1.1 0.6 0.3 -1.6 0.5 0.1 -1.4 0.8 0.5 0.7 0.2 0.7 -0.8 1.2 1.1 0.3 0.6 0.5 1.2
Medication: Allopurinol 0.4 0.6 4.5 -0.0 -0.3 -2.1 -0.4 -0.4 -1.1 -0.3 -0.4 -1.0 -0.9 -0.5 -0.4 -0.8 -0.4 0.4 -0.9 -0.0 -0.6 -0.7 -0.4 -1.1
Medication: Omeprazole 0.4 0.5 2.8 0.4 -0.2 -1.7 -0.0 -0.2 -1.4 -0.8 -0.2 -1.6 -0.8 -0.3 0.0 -0.0 0.1 -0.3 -0.5 -0.1 -0.4 -0.4 -0.1 -1.1
Medication: Seretide 50 evohaler 0.3 0.3 1.1 0.5 0.5 -0.6 0.4 0.7 0.7 -0.0 0.9 0.8 0.6 0.8 0.3 0.5 0.5 -0.2 0.5 0.3 0.5 0.5 0.4 1.1
Mean time to correctly identify matches 0.3 0.6 2.4 0.4 0.9 -0.4 0.6 0.8 0.6 0.9 0.7 0.7 0.5 1.5 0.5 0.4 0.8 -0.5 1.2 1.0 0.7 0.6 0.6 0.6
Heart disease (mother) 0.3 0.4 1.4 0.3 1.1 -0.5 0.1 0.3 1.0 0.1 0.7 1.2 0.6 0.6 -0.0 0.5 0.0 0.0 1.2 0.4 0.2 -0.0 0.3 0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 0.9 2.7 -0.5 -1.4 -0.8 -0.9 -0.7 0.4 -0.3 -0.5 0.3 -1.5 -1.6 -0.9 -0.7 -0.9 0.7 -1.6 -1.3 -0.7 -0.5 -0.7 -1.3
Whole body fat mass 1.1 4.7 7.9 -2.2 -2.4 -1.9 -2.7 -2.2 0.4 -2.8 -1.9 0.3 -1.7 -1.6 -2.7 -2.0 -2.4 2.6 -2.1 -2.3 -2.3 -2.6 -2.6 -1.9
Leg fat mass (right) 0.7 2.9 6.8 -1.5 -1.7 -1.8 -2.0 -1.7 0.4 -2.6 -1.5 0.2 -1.2 -1.1 -2.0 -1.5 -1.8 2.0 -1.5 -1.8 -1.8 -2.2 -2.0 -1.4
Arm predicted mass (right) 0.4 1.9 5.5 1.9 1.6 -0.1 1.3 0.9 -2.4 -0.0 0.4 -1.5 2.0 1.6 1.3 1.0 1.6 -1.3 1.4 1.1 0.9 0.9 0.9 2.0
Pulse rate, automated reading 0.1 0.4 1.4 1.0 0.6 1.1 0.4 0.8 0.6 1.2 0.5 0.7 -0.3 -0.4 0.5 0.7 0.5 -0.4 -0.1 0.4 0.7 -0.1 0.6 -0.3
Alcohol intake frequency. 1.0 2.2 5.9 1.5 2.4 0.4 1.2 2.1 2.2 0.7 2.1 2.4 0.5 0.6 1.2 2.3 1.2 -0.7 0.2 0.5 1.6 1.1 1.6 1.3
Comparative height size at age 10 1.8 10.1 17.4 3.7 2.8 2.9 3.3 3.6 0.3 4.2 2.7 1.3 3.6 3.0 3.5 3.5 3.8 -3.5 3.1 2.7 3.6 3.3 3.1 2.7
Number of full sisters 0.3 0.4 1.5 1.2 0.1 -0.4 0.6 0.8 -0.2 -0.1 0.8 -0.4 0.5 0.4 0.6 0.8 0.8 -0.7 -0.1 0.4 0.5 0.9 0.6 0.4
Suffer from ‘nerves’ 4.5 7.0 11.0 3.2 3.3 2.1 3.2 2.6 -0.9 1.8 2.1 -0.6 2.1 2.0 3.2 2.6 3.0 -3.3 2.5 3.1 2.8 2.9 3.0 3.2
Overall health rating 1.5 3.3 6.7 2.0 2.6 -0.4 1.7 2.1 2.4 2.0 2.2 2.0 0.9 0.8 1.7 2.1 1.5 -1.5 0.9 1.7 1.9 1.7 1.9 2.4
Chest pain or discomfort 0.6 0.9 3.3 0.7 1.4 -0.5 0.9 1.1 0.3 0.9 0.8 0.5 1.2 1.8 0.8 0.9 0.9 -0.6 1.5 1.1 0.8 0.5 0.8 0.5
Had major operations 1.1 1.3 3.9 -1.1 -1.0 -2.0 -1.0 -0.9 -0.8 0.9 -1.6 -1.3 -0.6 -1.2 -0.9 -1.0 -1.1 1.0 -1.4 -0.9 -1.1 -1.6 -1.1 0.4
Age at last live birth 0.9 1.3 3.2 0.9 1.5 0.6 1.3 1.0 -0.3 0.1 1.2 0.1 0.8 1.7 1.1 1.1 1.4 -1.1 1.2 1.5 1.2 1.8 0.9 0.8
Family relationship satisfaction 3.0 3.7 10.2 1.8 1.7 1.1 1.9 1.8 1.2 0.8 1.9 1.1 2.6 2.3 1.7 1.9 1.6 -1.6 3.2 2.3 1.7 1.8 2.1 2.3
Leg pain on walking 0.7 0.8 2.6 -0.9 -1.1 -1.6 -0.9 -0.7 0.5 -1.2 -0.3 0.5 -0.9 -1.0 -0.9 -0.3 -1.1 0.9 -1.2 -1.2 -0.8 -0.9 -0.5 -0.6
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.0 2.3 -0.7 -1.5 -0.3 -1.2 -1.2 -0.6 -1.4 -0.9 -0.9 -0.4 -1.0 -1.2 -0.7 -1.2 0.9 -1.0 -1.3 -1.3 -0.8 -1.2 0.0
Commuting to job workplace: Car/motor vehicle 2.9 3.4 8.9 2.1 1.2 0.7 1.9 2.0 0.8 1.9 2.1 1.0 3.0 1.8 2.0 1.9 1.8 -2.1 1.8 1.8 1.9 1.1 2.2 2.0
Illness, injury, bereavement, stress in last 2 years 2.8 3.4 5.8 -2.2 -2.4 0.5 -2.3 -2.2 -0.8 -1.9 -1.9 -1.0 -1.9 -1.0 -2.3 -2.2 -2.1 2.2 -0.6 -1.9 -2.3 -1.3 -2.2 -1.2
Medication: Aspirin 0.6 0.8 2.2 0.9 0.8 -0.0 0.7 1.0 0.9 0.6 1.1 1.3 0.9 1.5 0.6 0.5 0.9 -0.7 1.5 1.3 0.9 0.4 0.8 0.7
Supplements: Vitamin C 0.7 0.9 3.0 -1.7 -1.0 0.7 -0.9 -1.2 -0.8 -0.6 -1.3 -1.0 0.0 -0.1 -1.0 -0.8 -1.0 1.1 -0.0 -0.7 -1.1 -0.5 -1.2 -0.8
Knee pain experienced in last month 1.0 1.5 3.3 -1.0 -1.4 -1.8 -1.2 -1.2 0.1 -1.0 -1.0 -0.3 -1.8 -1.5 -1.2 -1.2 -1.3 1.1 -1.5 -1.2 -1.1 -1.6 -1.0 -0.9
Hypertension (Self-reported) 0.2 0.4 2.6 0.9 1.0 0.1 0.5 0.6 -1.6 -0.0 -0.1 -0.9 0.7 0.4 0.5 -0.0 0.9 -0.5 0.0 0.7 0.3 0.4 0.0 0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 1.7 -0.3 -0.3 -0.4 -0.5 -0.5 -1.0 -0.7 -1.1 -1.1 -1.3 -0.6 -0.5 -0.8 -0.5 0.4 -0.1 -0.7 -0.7 -0.8 -0.7 -1.2
Illnesses of father: Heart disease 0.5 0.7 3.2 -0.7 0.5 1.8 -0.5 -1.0 -1.5 -0.3 -0.9 -1.5 0.3 0.1 -0.5 -0.7 -0.6 0.5 1.0 -0.2 -0.8 -0.3 -0.7 0.8
Illnesses of siblings: Diabetes 0.7 0.9 2.3 1.2 0.5 -0.5 0.9 1.0 1.5 0.2 1.4 1.5 0.3 -0.0 1.0 1.4 0.7 -0.9 0.3 0.6 1.1 0.9 1.4 -0.1
Smoking status: Previous 0.1 0.1 0.8 -0.3 0.1 -0.8 -0.2 -0.1 -0.2 0.4 -0.6 -0.2 -0.1 0.4 -0.3 -0.9 -0.0 0.3 0.3 0.2 -0.3 -0.4 -0.3 -0.0
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.2 2.8 1.1 0.3 -0.1 1.1 1.0 0.1 1.5 1.2 0.2 1.5 0.5 1.3 1.7 1.3 -1.5 0.4 0.7 1.3 1.3 1.0 1.4
Whole body fat-free mass 0.4 2.2 5.6 1.9 1.6 0.4 1.4 0.9 -2.4 0.4 0.4 -1.6 2.3 1.8 1.4 1.2 1.8 -1.6 1.6 1.2 1.0 1.0 0.9 1.9
Leg fat-free mass (right) 0.1 0.7 2.6 0.9 1.1 -0.0 0.7 0.3 -1.6 0.1 0.0 -1.0 1.6 1.1 0.7 0.6 0.9 -0.8 0.9 0.7 0.4 0.3 0.3 1.2
Arm fat percentage (left) 2.7 10.7 16.1 -3.9 -3.5 -2.2 -4.0 -3.5 1.4 -3.9 -2.7 1.0 -2.8 -2.7 -4.0 -3.2 -3.9 4.0 -2.9 -3.3 -3.4 -3.7 -3.7 -2.8
Average weekly red wine intake 0.5 0.8 1.5 -1.2 -0.6 -0.4 -0.9 -1.1 -0.3 -0.9 -0.7 -0.2 -0.4 -1.2 -0.9 -1.1 -1.0 1.0 -1.0 -0.8 -0.8 -1.2 -0.9 -0.5
Handedness (chirality/laterality): Left-handed 0.2 0.2 1.8 -0.2 0.2 0.4 -0.0 0.0 1.3 -0.3 0.1 1.1 0.1 0.1 -0.1 0.0 -0.2 0.2 0.1 0.4 0.1 0.7 0.1 0.2
Mood swings 0.1 0.2 0.9 0.2 0.5 0.5 -0.0 -0.3 -0.8 0.7 -0.6 -0.9 -0.9 0.1 0.0 0.3 -0.1 0.0 -0.2 -0.4 -0.2 0.5 -0.1 0.3
Loneliness, isolation 0.2 0.3 1.0 -0.7 -1.0 -0.0 -0.6 -0.9 0.3 -0.7 -0.4 0.1 -0.1 -0.3 -0.6 -0.2 -0.8 0.5 0.3 -0.1 -0.6 0.0 -0.4 0.1
Long-standing illness, disability or infirmity 0.1 0.2 1.1 0.5 1.1 -0.1 0.3 0.3 -0.1 1.0 0.1 -0.2 0.1 -0.1 0.2 0.1 0.3 -0.2 0.1 0.6 0.2 0.6 0.1 0.5
Ever had bowel cancer screening 0.7 0.8 3.7 -0.4 -0.7 -0.7 -0.5 -0.9 -1.9 -0.4 -1.0 -1.7 -1.1 0.0 -0.5 -0.6 -0.6 0.4 0.3 -0.8 -1.0 -0.5 -0.4 -1.5
Diabetes diagnosed by doctor 0.1 0.2 0.6 0.1 0.6 0.1 -0.4 -0.3 -0.3 -0.7 -0.2 -0.4 -0.8 0.0 -0.4 -0.2 -0.4 0.5 0.0 -0.4 -0.5 -0.4 -0.3 -0.6
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 1.8 1.3 0.4 0.3 0.6 0.9 -0.0 0.6 0.7 0.0 0.4 0.5 0.8 1.1 0.8 -0.9 -0.3 0.2 0.8 1.3 0.6 -0.2
Friendships satisfaction 0.5 0.6 3.6 -0.5 -0.6 -0.4 -0.5 -0.2 1.7 -0.2 0.5 1.9 0.3 0.2 -0.6 -0.2 -0.6 0.8 1.2 -0.0 -0.2 -1.2 -0.0 0.2
Qualifications: nursing, teaching 0.2 0.4 1.8 0.8 -0.4 -0.3 0.1 0.1 -1.3 -0.3 -0.3 -1.1 0.5 0.7 0.0 -0.5 0.5 -0.2 1.1 0.2 -0.2 -1.0 0.0 0.4
Commuting to job workplace: Walk 0.6 0.7 2.3 0.3 1.1 -0.4 0.7 0.4 1.0 0.6 0.8 0.8 0.5 -0.2 0.8 1.4 0.5 -0.6 -1.0 0.5 0.9 1.0 0.7 1.5
Eye problems/disorders: Cataract 2.3 2.7 5.7 -1.7 -2.0 -0.9 -1.8 -1.6 -0.5 -0.8 -1.5 -0.9 -2.0 -1.5 -1.7 -2.2 -1.6 1.8 -1.9 -1.4 -1.7 -1.3 -2.0 -2.4
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 0.8 0.2 -0.1 0.1 -0.0 -0.3 -0.5 -0.7 -0.2 -0.9 -0.5 0.2 -0.1 -0.5 -0.1 0.0 0.8 0.6 -0.3 -0.5 0.0 0.9
Medication for cholesterol 0.6 1.0 5.3 -0.4 -0.7 -2.3 -0.5 -0.7 -0.6 0.2 -0.9 -1.4 -1.8 -0.7 -0.5 -0.5 -0.6 0.6 -0.9 -0.8 -0.7 -1.5 -0.5 -1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 0.9 2.4 1.3 -0.1 1.1 0.7 0.5 -1.5 0.5 0.5 -1.5 1.2 0.7 0.8 0.2 1.0 -1.1 1.5 1.1 0.4 0.9 0.7 1.0
Back pain experienced in last month 0.5 0.8 2.0 -1.4 -1.1 0.4 -1.0 -0.9 0.8 -0.5 -0.8 0.3 -0.7 -0.8 -1.1 -0.9 -1.4 1.3 0.0 -0.7 -1.1 -1.1 -0.6 -0.1
Mineral and other dietary supplements 1.6 2.2 4.3 1.2 1.5 0.4 1.4 1.5 1.9 2.0 1.8 2.1 1.4 0.3 1.5 1.6 1.4 -1.4 0.6 1.5 1.8 1.2 1.5 1.9
Breast cancer (self-reported) 0.9 1.1 3.2 -1.3 -0.8 -0.4 -1.2 -0.8 0.4 -0.6 -0.8 0.3 -1.8 -1.1 -1.2 -1.4 -1.1 1.4 -0.4 -1.0 -1.0 -1.2 -1.1 -1.5
Asthma (self-reported) 0.1 0.3 1.3 -0.1 -0.2 -1.2 -0.3 -0.5 -0.3 0.7 -0.3 -0.0 -0.9 -0.7 -0.3 -0.5 -0.3 0.3 -0.8 -0.3 -0.3 -0.3 -0.2 -0.8
Osteoporosis (self-reported) 0.8 1.0 4.0 -0.9 -0.6 -0.6 -0.9 -0.8 -0.1 -1.0 -0.7 -0.1 -1.8 -2.0 -0.8 -0.8 -1.1 0.8 -2.0 -1.1 -0.8 -0.5 -0.8 -0.8
Osteoarthritis (self-reported) 0.7 0.9 3.6 -0.9 -0.1 -1.1 -0.9 -1.0 -0.4 -0.6 -0.8 -0.7 -1.9 -1.3 -0.9 -1.1 -1.2 1.0 -0.5 -0.6 -1.1 -1.3 -0.7 0.1
Medication: Aspirin 0.5 0.7 1.7 0.9 0.7 -0.3 0.6 0.9 0.9 0.6 1.1 1.3 0.7 1.3 0.5 0.4 0.8 -0.6 1.1 1.2 0.8 0.3 0.7 0.4
Medication: Gliclazide 0.6 0.7 2.0 -0.3 -0.1 -1.4 -0.5 -0.6 -0.9 0.2 -1.1 -1.0 -1.1 -0.8 -0.5 -0.5 -0.7 0.4 -0.8 -0.8 -0.7 -1.2 -0.5 -1.4
Illnesses of father: None of the above (group 1) 0.4 0.5 1.7 0.3 -0.1 0.0 0.5 0.9 1.2 0.8 0.7 1.3 0.4 1.1 0.5 0.4 0.5 -0.5 0.7 0.4 0.7 0.3 0.7 -0.8
Smoking status: Current 0.4 0.6 4.0 0.6 -0.9 -0.6 -0.1 0.6 2.0 0.8 0.8 1.0 -0.6 -1.2 0.2 0.5 -0.1 -0.3 -0.9 -0.3 0.4 -0.2 0.4 -0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.3 3.1 -0.0 -0.5 0.5 -0.2 -0.3 -0.7 -1.8 0.2 -0.2 0.5 0.4 -0.3 -0.1 0.0 0.4 0.4 -0.0 -0.3 0.2 -0.2 -0.0
Whole body water mass 0.4 2.1 5.8 1.8 1.6 0.4 1.4 0.9 -2.4 0.2 0.4 -1.6 2.2 1.8 1.4 1.1 1.7 -1.6 1.6 1.2 1.0 1.0 0.9 1.9
Leg predicted mass (right) 0.1 0.8 2.7 0.9 1.1 -0.1 0.7 0.3 -1.6 0.1 0.0 -1.1 1.6 1.1 0.7 0.6 1.0 -0.9 1.0 0.7 0.4 0.3 0.3 1.2
Arm fat mass (left) 1.4 5.6 10.3 -2.6 -2.5 -2.0 -2.9 -2.6 0.5 -3.2 -2.0 0.4 -1.8 -1.6 -2.9 -2.2 -2.7 2.9 -2.1 -2.5 -2.5 -2.8 -2.8 -1.9
Number of self-reported non-cancer illnesses 0.1 0.2 0.8 -0.1 0.9 0.0 0.0 0.3 0.6 -0.5 0.2 0.7 0.2 0.7 -0.1 -0.4 0.1 0.1 0.8 0.6 0.1 -0.4 -0.0 0.6
Average weekly champagne plus white wine intake 2.9 4.0 12.1 2.1 1.6 2.5 1.8 2.0 0.5 0.7 1.7 1.0 2.6 2.4 1.7 1.6 2.0 -1.5 3.5 2.2 1.8 1.5 1.9 2.9
Miserableness 3.3 5.7 10.4 2.2 3.2 2.8 2.6 2.4 1.1 1.8 2.4 1.2 1.9 2.5 2.5 2.6 2.5 -2.3 2.1 2.4 2.6 2.8 2.4 2.6
Guilty feelings 0.1 0.2 0.8 -0.8 0.9 0.6 -0.0 -0.4 -0.1 -0.5 -0.3 0.2 0.2 0.5 -0.2 -0.5 -0.3 0.4 0.7 0.2 -0.2 0.0 -0.1 0.4
Wears glasses or contact lenses 0.3 0.3 0.8 -0.7 0.5 0.1 -0.5 -0.4 -0.9 -0.5 -0.4 -0.4 -0.3 0.2 -0.6 -0.7 -0.5 0.8 -0.3 -0.6 -0.6 -0.8 -0.6 -0.8
Ever taken oral contraceptive pill 0.5 0.5 2.1 0.5 0.0 0.8 0.6 0.2 -0.9 0.9 0.1 -0.6 1.4 0.8 0.7 0.4 0.7 -1.1 0.9 0.7 0.5 1.0 0.5 0.2
Hearing aid user 0.2 0.2 1.5 0.2 0.0 0.0 0.3 0.0 -0.5 -1.0 0.2 -0.4 0.9 0.3 0.3 0.5 0.3 -0.5 1.2 0.6 0.2 0.2 0.3 0.3
Mother’s age at death 0.4 0.5 5.5 -0.5 -0.3 2.3 -0.0 0.0 0.5 0.8 -0.1 0.6 0.8 0.8 -0.1 -0.1 0.0 0.2 0.9 0.1 0.0 0.6 -0.2 -0.1
Financial situation satisfaction 2.3 2.8 7.2 1.5 0.7 2.0 1.5 1.5 2.4 1.0 2.7 2.6 1.2 0.5 1.6 2.0 1.2 -1.5 1.0 1.8 1.9 1.6 2.0 0.6
Tinnitus: Yes, now most or all of the time 0.6 0.7 4.2 -0.0 -0.3 0.7 0.6 0.0 -2.0 0.2 -0.3 -1.8 1.7 1.0 0.6 0.1 0.6 -0.8 0.9 0.7 0.1 0.6 0.3 0.4
Commuting to job workplace: Public transport 0.6 0.8 1.9 -0.6 -1.2 0.2 -1.0 -0.8 -0.5 -1.2 -0.8 -0.3 -1.4 -0.9 -0.9 -0.8 -0.7 1.0 -0.4 -0.9 -0.8 -0.4 -1.0 -1.3
Eye problems/disorders: Glaucoma 0.6 0.7 1.6 -1.2 -0.8 0.4 -0.9 -1.3 -0.2 -0.3 -0.9 -0.4 -0.5 -0.9 -0.9 -1.2 -1.1 1.1 -0.7 -0.8 -1.0 -0.3 -0.8 -0.4
Medication: Blood pressure 1.5 2.8 5.0 1.9 2.2 2.0 1.8 1.7 -0.9 0.7 1.3 0.1 2.2 1.8 1.7 1.0 2.0 -1.8 1.6 2.2 1.6 1.9 1.5 1.6
Pain type(s) experienced in last month: Hip pain 0.6 0.7 2.7 0.7 0.2 1.2 0.5 0.7 0.8 1.0 1.1 0.7 0.7 1.1 0.4 0.4 0.6 -0.4 1.6 0.9 0.5 0.5 0.8 1.2
Supplements: Fish oil (including cod liver oil) 0.7 0.9 2.9 -0.9 -0.7 0.2 -0.8 -0.8 -1.7 -0.9 -1.3 -1.7 -0.8 0.4 -0.9 -0.9 -0.8 0.8 0.1 -1.2 -1.2 -0.5 -0.9 -1.1
High cholesterol (Self-reported) 0.3 0.6 2.5 -1.1 -0.1 0.5 -0.7 -0.8 -0.1 -1.6 -0.6 -0.2 -1.0 -0.4 -0.8 -1.1 -0.6 0.8 -0.3 -0.4 -0.8 -0.8 -0.9 -0.4
Medication: Bendroflumethiazide 0.2 0.4 2.4 0.7 0.3 0.6 0.3 0.2 -1.6 -0.2 0.0 -0.9 0.8 0.1 0.3 -0.1 0.6 -0.5 0.3 0.8 0.1 0.1 0.1 1.2
Medication: Paracetamol 0.1 0.1 0.4 0.1 -0.3 -0.6 -0.2 -0.2 0.1 -0.2 0.2 -0.4 -0.2 -0.6 -0.2 -0.1 -0.4 0.0 -0.1 -0.2 -0.4 -0.2 0.1 0.5
Medication: Lisinopril 0.3 0.4 2.6 0.2 0.3 0.2 -0.0 -0.0 -1.6 0.2 -0.9 -1.6 -0.6 -0.1 0.0 -0.4 0.2 -0.1 -0.1 0.2 -0.3 -0.4 -0.4 -0.6
Medication: Atorvastatin 0.3 0.4 3.9 0.3 0.5 -0.9 0.0 -0.4 -0.1 -2.0 0.3 -0.4 -1.2 -0.0 -0.0 -0.4 0.3 -0.0 -0.7 -0.3 -0.0 0.1 0.0 -0.5
Illnesses of father: High blood pressure 1.3 1.6 3.8 -1.0 -1.6 -0.3 -1.3 -1.3 -0.7 -1.5 -1.2 -0.8 -0.9 -1.9 -1.2 -1.2 -1.2 1.1 -1.9 -1.2 -1.2 -1.1 -1.4 -0.9
Alcohol drinker status: Never 1.6 1.9 3.8 1.1 1.0 1.7 1.2 1.5 1.4 0.9 1.7 1.2 1.7 1.4 1.1 1.4 1.2 -1.0 1.8 1.2 1.2 1.2 1.4 2.0
Ever smoked 0.2 0.4 1.1 0.7 0.1 -1.0 0.4 1.1 1.0 0.7 0.9 0.9 -0.1 -0.2 0.6 0.6 0.6 -0.7 0.1 0.2 0.8 0.2 0.6 -0.1
Basal metabolic rate 0.1 0.8 3.8 1.1 0.8 -0.0 0.6 0.3 -2.0 -0.3 -0.1 -1.3 1.6 1.1 0.7 0.6 1.0 -0.8 0.9 0.5 0.4 0.3 0.2 1.2
Leg fat percentage (left) 1.7 6.3 10.3 -2.6 -2.9 -1.9 -3.1 -2.5 1.2 -3.1 -1.9 0.9 -2.2 -2.3 -3.1 -2.3 -2.9 3.1 -2.2 -2.7 -2.6 -3.2 -2.8 -1.9
Arm fat-free mass (left) 0.3 1.7 3.8 1.7 1.5 0.1 1.2 0.9 -1.9 0.1 0.5 -1.2 2.0 1.7 1.2 1.1 1.5 -1.3 1.5 1.0 0.9 0.7 0.9 1.9
Number of operations (self-reported) 0.8 1.2 2.9 -1.2 -0.7 -0.9 -1.1 -1.0 -1.6 -0.7 -1.5 -1.6 0.0 -0.7 -1.1 -1.7 -1.2 1.2 -0.4 -0.1 -1.4 -0.9 -1.2 0.5
Average weekly beer plus cider intake 3.1 4.5 7.2 -1.8 -2.5 -2.3 -2.3 -2.1 -0.5 -2.0 -1.8 -0.9 -2.4 -2.7 -2.2 -1.9 -2.3 2.0 -2.2 -2.3 -2.3 -2.3 -2.0 -2.5
Irritability 1.1 1.9 3.9 1.6 2.0 1.0 1.5 1.2 -0.4 1.2 0.9 -0.2 1.3 1.8 1.4 1.6 1.5 -1.4 1.6 1.6 1.2 1.7 1.2 1.3
Risk taking 0.3 0.5 1.6 -0.7 -0.8 0.3 -0.8 -0.6 0.2 -0.3 -0.5 0.3 -0.5 -1.1 -0.8 -0.6 -0.6 1.0 -0.6 -0.7 -0.6 -1.3 -0.8 0.6
Ever had prostate specific antigen (PSA) test 1.0 1.2 3.5 1.2 1.9 0.5 1.2 1.3 -0.2 1.0 1.2 0.5 0.8 1.1 1.1 1.1 1.2 -0.9 0.5 0.9 1.1 1.2 1.1 1.1
Fractured/broken bones in last 5 years 0.2 0.2 0.8 0.5 0.9 -0.5 0.4 -0.1 -0.6 0.6 -0.1 -0.8 -0.4 -0.8 0.4 0.1 0.2 -0.2 -0.6 0.0 0.2 0.1 0.3 0.0
Age started oral contraceptive pill 0.8 1.0 2.4 0.8 0.9 1.5 0.7 0.8 -0.2 -1.0 1.2 0.2 0.6 1.1 0.6 0.2 0.9 -0.7 1.5 1.4 0.6 1.3 0.7 1.5
Diastolic blood pressure, automated reading 0.3 1.0 5.9 0.0 -0.1 0.2 -0.7 -0.4 -2.4 -0.2 -1.7 -2.0 -0.4 -1.1 -0.6 -0.7 -0.2 0.5 -1.0 -0.8 -0.8 -0.7 -1.3 0.2
Ever depressed for a whole week 0.7 0.8 3.3 -0.6 -0.6 0.9 -0.7 -0.8 -1.6 0.5 -1.5 -1.8 -0.9 -0.5 -0.6 -1.3 -0.5 0.3 -0.6 -0.5 -0.9 -0.6 -1.1 -0.7
Unable to work because of sickness or disability 0.1 0.1 0.6 0.5 0.3 0.1 0.2 0.5 -0.3 0.8 -0.1 -0.2 -0.3 -0.2 0.3 0.1 0.3 -0.3 -0.1 0.2 0.2 0.2 0.2 0.0
Commuting to job workplace: Cycle 1.1 1.3 4.7 1.0 2.2 -0.0 1.4 1.2 -0.0 1.2 1.2 0.3 0.7 1.4 1.3 0.8 1.4 -1.4 0.7 1.4 1.4 1.4 0.9 0.7
Myopia 3.8 5.5 10.1 2.6 2.7 -0.1 2.8 2.6 1.2 2.2 2.5 1.4 2.2 1.6 2.9 3.2 2.5 -2.8 1.8 2.2 2.8 2.1 2.9 2.0
Vascular/heart problems diagnosed by doctor 0.1 0.2 0.9 -0.5 -0.7 -0.2 -0.2 -0.5 1.0 -0.1 0.3 0.4 -0.6 -0.2 -0.2 0.3 -0.6 0.2 -0.1 -0.5 -0.2 -0.4 0.1 -0.5
Cholesterol lowering medication 0.6 0.8 3.1 -1.1 -0.5 0.2 -1.1 -0.8 0.8 -1.8 -0.2 0.9 -0.9 -0.7 -1.1 -0.8 -1.0 1.1 -0.9 -0.9 -0.8 -0.4 -0.9 -0.7
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 1.7 0.6 0.3 -1.3 0.2 0.2 -0.9 -0.8 0.2 -1.0 -0.4 -0.1 0.2 0.1 0.3 -0.3 -0.2 0.2 -0.0 -0.1 0.1 -0.5
Pain experienced in last month 0.1 0.1 0.8 0.2 0.2 -0.7 0.0 0.1 -0.9 0.1 -0.2 -0.6 0.1 -0.1 0.1 -0.2 0.2 -0.1 -0.3 -0.2 -0.0 -0.1 -0.0 0.1
Supplements: Calcium 0.1 0.2 1.2 0.2 0.5 0.3 0.2 0.6 -0.4 1.1 0.1 -0.0 -0.5 0.1 0.3 0.3 0.2 -0.3 0.3 0.1 0.3 -0.2 0.3 -0.6
Basal cell carcinoma (self-reported) 2.5 3.0 5.3 -2.1 -2.3 -0.7 -1.8 -1.6 0.3 -1.6 -1.6 -0.1 -1.6 -2.3 -1.8 -1.7 -2.1 1.9 -1.9 -1.8 -1.7 -1.7 -1.4 -2.2
Heart attack/myocardial infarction (self-reported) 0.2 0.3 1.6 0.4 -0.1 0.1 0.2 0.5 0.5 0.4 0.6 0.4 1.3 1.1 0.2 -0.0 0.3 -0.3 0.9 0.7 0.3 0.4 0.3 0.5
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 0.9 0.8 0.3 0.9 0.5 0.7 0.3 -0.4 0.8 0.4 0.5 0.6 0.5 1.0 0.8 -0.7 0.5 0.2 0.6 0.6 0.4 1.0
Heart disease (siblings) 0.6 0.7 3.2 0.4 1.2 -0.3 0.5 0.7 1.8 0.2 1.5 1.3 0.3 0.1 0.5 1.1 0.2 -0.3 0.8 0.7 0.7 0.2 0.8 1.0
Alcohol drinker status: Previous 0.6 0.6 3.2 1.0 1.8 -0.1 0.8 0.9 0.6 0.7 0.8 0.8 0.1 -0.2 0.8 0.7 0.8 -0.7 -0.8 0.4 1.0 0.7 0.8 0.7
Pack years of smoking 1.2 1.7 5.9 -1.1 -1.1 -1.7 -1.6 -0.7 2.4 -0.5 -0.3 1.6 -1.3 -1.5 -1.5 -0.8 -1.4 1.4 -1.3 -1.3 -0.9 -1.7 -1.2 -0.0
Impedance of whole body 0.8 3.9 9.4 -2.7 -3.1 0.6 -2.1 -1.2 2.9 -0.5 -0.9 2.2 -1.9 -2.3 -2.0 -1.3 -2.3 2.0 -2.3 -2.0 -1.3 -0.9 -1.7 -2.5
Leg fat mass (left) 0.7 2.9 6.0 -1.6 -1.8 -1.7 -2.1 -1.7 0.6 -2.4 -1.4 0.5 -1.2 -1.2 -2.1 -1.5 -1.8 2.1 -1.6 -1.9 -1.8 -2.2 -2.0 -1.3
Arm predicted mass (left) 0.3 1.5 4.4 1.7 1.3 -0.0 1.1 0.8 -2.1 -0.0 0.3 -1.4 1.8 1.6 1.1 0.9 1.5 -1.2 1.3 0.9 0.7 0.7 0.7 1.7