Hub : Genes

RP11-434D12.1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Visceral Omentum 0.140 0.0460 0.00120 0.062 NA 0.003 NA 0.010 0.00037 NA 0.23000 NA 9.1e-02
2 GTEx Brain Cerebellum 0.344 0.1140 0.00260 0.037 NA -0.008 NA 0.000 0.03000 NA 0.67000 NA 3.2e-01
3 GTEx Colon Transverse 0.145 0.0580 0.00740 -0.001 NA 0.060 NA 0.010 0.37000 NA 0.00082 NA 9.9e-02
4 GTEx Esophagus Mucosa 0.120 0.0500 0.00660 -0.003 NA 0.015 NA -0.001 0.58000 NA 0.03300 NA 3.9e-01
5 GTEx Heart Atrial Appendage 0.200 0.0730 0.00410 -0.006 NA 0.025 NA 0.014 0.83000 NA 0.02600 NA 7.2e-02
6 GTEx Lung 0.105 0.0392 0.00260 0.026 NA 0.016 NA 0.018 0.00440 NA 0.01900 NA 1.4e-02
7 GTEx Skin Not Sun Exposed Suprapubic 0.151 0.0500 0.00048 0.069 NA 0.070 NA 0.098 0.00013 NA 0.00011 NA 4.7e-06
8 GTEx Skin Sun Exposed Lower leg 0.122 0.0420 0.00140 0.018 NA 0.037 NA 0.015 0.01100 NA 0.00046 NA 2.0e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.9 1.5 2.2 1.4 1.2 1.4 -0.1 1.3 1.4 0.9 1.5
Bipolar Disorder or Schizophrenia 0.5 1.1 2.7 1.1 1.5 1.2 0.2 1.6 0.7 0.8 0.7
Depressed Affect (Nagel 2018) 1.0 2.2 4.4 1.4 0.4 -1.1 1.3 2.0 1.0 2.1 1.7
Depression (Nagel 2018) 1.1 1.7 4.0 1.5 0.7 0.8 2.0 -0.3 1.2 1.8 1.2
Intelligence (Savage-Jansen 2018) 0.2 0.5 1.8 -0.1 -0.6 0.6 -0.5 -1.3 -0.8 -0.6 0.4
Neuroticism (Nagel 2018) 0.4 0.8 2.3 0.9 0.1 -1.0 0.3 1.5 1.0 1.2 0.3
Schizophrenia (2018) 0.1 0.3 1.0 0.2 1.0 0.5 0.1 1.0 -0.2 0.3 0.1
Schizophrenia vs Biploar Disorder 0.3 0.4 1.4 -0.5 1.2 1.1 -0.3 0.5 -0.3 0.0 0.2
Worry (Nagel 2018) 0.5 1.0 6.7 0.6 -0.2 -2.6 -0.4 0.5 0.5 0.4 -0.4
Alzheimer’s Disease (in mother) 0.7 0.8 3.7 -0.8 -0.3 0.2 -1.9 -0.7 0.8 -0.6 -0.8
Alzheimer’s Disease (in father) 1.7 1.8 6.9 -0.7 0.9 -2.6 1.9 -1.3 -0.2 -0.8 -0.3
Alzheimer’s Disease (including proxy) 0.1 0.2 0.8 -0.2 0.9 -0.7 0.5 -0.4 0.1 -0.2 -0.1
Crohns Disease (2017) 0.2 0.4 1.0 -0.6 -1.0 -0.3 -0.1 -0.2 -0.8 -0.2 -0.8
Irritable Bowel Disease (IBD) 0.5 1.2 3.6 -0.8 -1.9 -1.6 -0.0 -0.1 -0.6 -0.4 -1.4
Ulcerative Colitis (UC) 0.4 0.8 3.6 -0.2 -1.4 -1.9 0.2 -0.0 -0.5 -0.3 -0.9
Major Depression (MDD) 0.7 0.9 2.4 -1.3 -0.9 -1.6 -1.2 0.1 -0.1 -0.5 -0.7
Reaction Time 0.8 1.5 3.0 -1.1 -1.4 -0.9 -1.7 -0.7 -1.7 0.8 -0.9
Verbal and Numeric Reasoning (VNR) 0.3 0.6 1.8 -0.2 -1.2 0.6 -0.1 -1.0 -1.3 -0.0 -0.6
Breast Cancer 0.7 1.6 5.6 -0.8 -0.0 -1.5 0.7 -2.4 -1.6 -1.2 -0.4
Ovarian Cancer 1.5 2.0 6.2 1.3 -0.6 -0.3 2.5 1.6 -0.2 1.7 1.5
Prostate Cancer 0.3 0.4 1.4 0.5 0.9 0.6 -0.1 -0.0 1.2 0.1 -0.2
Age at First Birth 0.7 1.0 4.5 -0.0 0.2 -1.0 2.1 -0.7 0.5 1.4 0.4
Bipolar Disorder (2011) 0.2 0.2 0.5 0.4 0.4 0.7 -0.4 0.5 0.3 0.2 0.1
Body Mass Index (BMI) (2010) 0.2 0.3 0.8 -0.8 -0.9 -0.6 -0.8 0.2 -0.1 -0.3 -0.2
Coronary Artery Disease (CAD) 0.7 0.9 4.1 -0.0 1.2 0.9 0.5 -2.0 0.4 0.4 0.3
Crohns Disease (2012) 0.4 0.7 1.7 -0.8 -1.3 0.8 -0.7 -1.2 -0.0 -0.1 -0.7
Mean Putamen Volume 0.6 0.7 2.6 0.8 0.8 -0.6 0.1 0.4 0.7 1.6 0.8
Fasting Glucose 0.4 0.5 1.5 -0.2 -1.2 -0.9 -0.5 0.1 -0.1 -0.8 -0.8
HbA1C 1.9 2.2 11.4 -1.1 -0.1 -1.1 0.4 -3.4 -0.4 -0.8 -1.5
HDL Cholesterol 0.2 0.4 1.0 -0.5 -0.9 0.0 0.0 -1.0 0.7 -0.6 -0.2
LDL Cholesterol 0.3 0.4 2.5 -0.5 0.4 -0.5 -1.6 -0.4 -0.5 -0.2 -0.0
Lupus 0.1 0.1 0.3 0.6 -0.5 0.0 0.2 -0.5 -0.1 0.4 -0.1
Neuroticism (2016) 0.8 1.2 2.7 -1.6 1.0 -1.3 -0.8 1.0 0.1 -0.8 -1.3
Primary Biliary Cirrhosis 0.3 0.5 1.7 0.4 0.6 1.3 -0.9 0.7 -0.3 0.4 -0.1
Rheumatoid Arthritis 1.5 2.1 5.4 -1.7 -0.5 0.3 -0.7 -0.8 -2.1 -1.7 -2.3
Schizophrenia (2014) 0.6 1.4 3.2 1.0 1.0 1.5 -0.1 1.8 0.8 1.0 1.4
Triglycerides 1.1 1.7 4.2 -1.7 -0.1 -0.1 -1.3 0.2 -1.1 -1.9 -2.0
Type 2 Diabetes (T2D) (2012) 0.4 0.5 1.3 1.2 -0.1 -0.1 0.7 0.3 0.8 0.7 0.8
Ulcerative Colitis 0.9 1.3 3.6 -1.0 -1.3 -1.5 -0.4 -0.1 -0.7 -1.0 -1.9
Blood Eosinophil Count 0.3 2.5 8.1 0.9 0.0 2.8 2.5 -0.5 2.0 0.6 0.5
Blood Platelet Count 0.4 4.7 11.1 -3.3 -1.3 -1.4 -0.8 -1.9 -1.1 -3.3 -2.6
Blood Red Count 0.4 3.9 20.2 -1.4 -4.5 -0.9 -0.2 -1.0 -1.4 -0.9 -2.1
Blood White Count 0.3 2.3 9.5 -0.4 0.4 -0.2 3.1 1.9 2.0 0.2 -1.1
Heel T-Score 0.4 2.8 7.6 2.7 2.3 -0.2 0.7 0.5 0.9 -0.5 2.8
BMI 0.1 0.5 1.6 -0.4 1.2 -0.9 0.7 0.9 0.5 -0.3 -0.1
Height 0.4 8.3 33.9 -2.3 -5.8 -1.4 -3.3 2.1 -1.8 -0.3 -2.5
Waist Hip Ratio (WHR) 0.4 1.6 6.8 0.2 -1.4 2.6 1.8 -0.5 -0.2 0.0 0.7
Systolic Blood Pressure 0.3 1.3 2.8 0.7 0.8 1.5 -1.7 -1.2 0.6 -1.0 1.0
Smoking Status 1.9 4.6 13.2 2.8 0.6 1.4 1.9 -0.2 0.9 3.6 2.9
Allergy or Eczema 0.2 0.5 2.9 0.3 -0.1 0.0 0.5 -0.6 -0.4 -0.4 -1.7
Cardiovascular Disease 0.2 0.7 4.0 -0.4 -0.0 0.4 0.8 -2.0 -0.5 -0.5 0.7
Hypothyroidism (self reported) 1.0 2.3 4.2 2.1 -0.2 1.3 1.6 0.8 1.7 2.0 1.5
Respiratory disease 0.2 0.5 2.5 -0.2 0.4 0.7 0.1 1.6 0.1 -0.6 0.3
Type 2 Diabetes (T2D) (2018) 0.5 0.9 3.3 -0.0 -0.4 1.8 -0.0 1.4 1.2 0.1 0.7
Lung FEV1/FVC ratio 0.7 3.6 16.6 1.1 -2.9 -0.1 -1.5 -0.1 -4.1 0.0 0.1
Lung FVC 0.9 4.4 8.4 -2.6 0.1 -2.7 -0.7 -2.1 -0.8 -2.9 -2.6
Neuroticism 0.8 2.0 4.6 1.1 1.0 -1.8 0.5 2.2 0.9 2.0 0.9
Chronotype (morning person) 0.6 1.4 3.3 -1.1 -1.5 -1.1 -0.3 -1.8 -0.9 -1.4 -0.7
Hair Pigment 0.0 0.5 1.3 -0.1 -1.2 -0.7 1.1 0.2 0.5 0.3 -0.4
Tanning 0.0 0.2 0.7 -0.4 0.7 -0.4 0.6 -0.8 0.2 0.0 -0.2
Hand grip strength (left) 0.3 0.8 2.3 -0.4 -0.3 1.5 -1.2 1.1 0.7 0.3 0.5
Number of treatments/medications taken 0.6 1.0 2.5 -0.6 -1.3 -0.9 0.8 -1.2 -1.6 -0.6 -0.6
Average weekly spirits intake 0.8 1.0 4.7 -0.3 -0.4 0.2 2.2 1.2 -1.1 0.1 -0.3
Sensitivity / hurt feelings 0.5 0.8 3.0 1.0 0.8 -0.1 0.2 1.7 0.1 1.4 0.2
Frequency of depressed mood in last 2 weeks 0.7 1.0 3.3 0.5 0.9 -0.3 1.3 0.2 1.8 1.3 0.5
Hearing difficulty/problems: Yes 0.9 1.3 3.9 1.3 0.2 0.8 0.0 1.7 -0.0 2.0 1.2
Relative age of first facial hair 0.7 1.5 3.8 1.6 -0.6 0.7 0.7 0.7 2.0 1.9 0.2
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 1.4 -0.5 -0.8 -0.4 -1.2 -0.5 -0.7 -1.0 0.1
Ever used hormone-replacement therapy (HRT) 1.3 1.7 3.8 -1.7 0.3 -1.9 -1.6 0.5 -1.3 -0.8 -1.2
Ever had hysterectomy (womb removed) 0.5 0.6 2.3 -0.3 -0.5 -1.3 -0.5 -0.5 -1.5 -0.0 -0.1
Systolic blood pressure, automated reading 0.4 1.2 5.1 0.8 0.1 2.3 -0.9 1.0 0.9 -0.2 1.3
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 2.0 -0.0 -0.3 1.4 -0.2 -0.7 0.4 0.3 0.6
Angina 0.3 0.4 1.1 0.3 -0.7 1.0 0.1 0.4 0.6 0.6 -0.5
Medication for hormone replacement therapy 1.3 1.4 3.4 -0.8 0.5 -1.8 -1.2 -0.8 -1.5 -0.7 -1.4
Vitamin and mineral supplements 1.1 1.5 3.8 1.1 -0.3 2.0 0.9 1.1 0.7 1.4 1.5
Supplements: Zinc 1.0 1.1 3.2 0.7 1.8 -0.3 0.1 1.1 1.4 1.0 0.9
Medication: Co-codamol 0.9 1.1 2.7 0.9 0.7 -0.2 1.6 1.6 1.1 0.6 0.6
Medication: Metformin 0.7 1.0 3.7 -0.2 -0.3 1.9 -1.6 -0.6 1.0 0.5 0.5
Diabetes (father) 1.7 2.1 4.2 -1.5 -1.1 -1.7 -0.1 -1.8 -2.1 -1.0 -1.2
Diabetes (mother) 0.2 0.2 0.8 -0.2 -0.0 0.9 0.2 -0.8 0.3 -0.1 -0.5
Severe depression (siblings) 0.3 0.3 1.1 0.2 1.0 -0.6 0.6 0.6 0.0 0.6 0.3
Pack years adult smoking proportion 0.4 0.6 1.3 -0.3 -0.7 1.0 1.1 -0.8 -0.9 0.2 -0.7
Impedance of leg (right) 0.9 4.4 12.6 3.5 -0.5 2.0 1.5 1.1 0.3 3.4 1.8
Leg fat-free mass (left) 0.2 1.2 3.0 -1.7 -1.3 -1.5 -0.6 0.2 -0.4 -0.8 -0.9
Trunk fat percentage 0.8 3.1 5.7 2.4 -0.7 0.8 2.3 2.0 0.7 2.3 1.6
Hand grip strength (right) 0.3 0.8 1.7 0.5 0.2 1.2 -0.7 1.3 0.5 0.8 1.3
Townsend deprivation index at recruitment 0.4 0.6 1.3 -0.9 -1.0 -0.5 -0.5 -1.2 -0.4 -0.4 -0.6
Current tobacco smoking 0.6 1.0 2.1 0.9 -0.7 0.6 1.5 -0.9 -0.4 1.4 1.1
Average weekly fortified wine intake 0.2 0.2 0.7 0.1 0.5 0.4 0.0 -0.8 -0.4 -0.3 -0.2
Maternal smoking around birth 0.5 0.8 2.2 0.1 -1.5 -0.5 1.0 0.0 1.4 0.6 -0.7
Fed-up feelings 0.4 0.7 1.8 0.3 -0.2 -1.0 0.5 0.9 0.9 1.3 0.8
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.5 1.6 0.6 0.5 -0.1 1.3 -0.1 -0.1 1.1 0.4
Relative age voice broke 0.2 0.3 0.7 0.8 -0.3 -0.4 0.0 0.8 0.5 0.7 0.1
Taking other prescription medications 0.6 0.9 3.2 -1.3 -0.2 -1.0 0.0 0.0 -1.8 -1.1 -0.6
Age when periods started (menarche) 0.7 1.6 4.6 -1.1 -1.5 -0.1 -0.5 -0.6 -1.7 -1.1 -2.1
Bilateral oophorectomy (both ovaries removed) 1.6 1.8 4.8 -1.3 -0.9 -0.5 -1.7 -0.2 -2.2 -1.4 -1.3
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.8 7.0 2.6 0.9 -0.3 0.4 1.5 1.3 0.5 1.4
Tinnitus: Yes, but not now, but have in the past 1.7 1.8 8.3 0.8 1.3 1.0 -0.6 -0.4 2.9 1.3 -0.8
Qualifications: CSEs or equivalent 0.5 0.7 1.9 1.4 0.7 -0.1 -0.6 -1.3 0.2 0.9 -0.0
Serious illness, injury or assault to yourself 0.8 1.0 4.5 -0.5 -2.1 -0.7 -0.4 -0.3 -0.9 -0.1 -1.2
High blood pressure 0.8 2.1 4.3 -1.8 -1.5 0.5 -1.5 -2.1 -1.4 -1.8 -0.0
Hayfever, allergic rhinitis or eczema 0.1 0.3 0.8 0.1 0.1 0.3 0.4 -0.9 -0.1 -0.5 -0.9
Multivitamins +/- minerals 1.1 1.4 3.3 -1.4 -0.3 -1.8 -0.4 -1.1 -0.8 -1.6 -1.3
Stomach or abdominal pain in last month 1.9 2.4 5.6 -1.0 -0.7 -1.9 -1.3 -1.9 -1.0 -1.3 -2.4
Supplements: Glucosamine 1.1 1.5 4.5 -1.8 0.3 -1.3 -0.2 -0.1 -0.2 -2.1 -1.5
Diverticular disease/diverticulitis (self-reported) 0.6 0.7 2.0 0.1 1.0 0.6 -1.3 -0.3 1.4 -0.5 -0.8
Medication: Atenolol 0.5 0.6 2.4 -0.2 -1.5 0.5 0.3 -0.8 1.2 0.2 -0.4
Medication: Levothyroxine sodium 0.2 0.3 1.0 0.3 -1.0 0.3 -0.8 -0.4 0.2 0.2 0.4
Sitting height 0.2 1.2 4.0 0.2 -0.5 -0.9 -0.8 1.3 1.4 2.0 0.6
Chronic bronchitis/emphysema (father) 1.9 2.3 8.1 1.4 0.9 1.3 1.7 0.1 2.8 1.6 0.6
High blood pressure (mother) 1.2 1.7 3.2 1.6 -0.3 1.8 0.9 0.6 1.8 1.5 1.0
Body mass index (BMI) 0.1 0.4 1.7 0.1 0.5 -0.3 1.3 0.5 0.3 0.1 0.7
Impedance of leg (left) 1.3 6.4 17.3 4.1 -0.6 2.4 1.6 1.3 1.0 4.2 2.5
Leg predicted mass (left) 0.2 1.1 2.9 -1.7 -1.4 -1.5 -0.6 0.2 -0.3 -0.7 -0.9
Trunk fat mass 0.4 1.9 4.2 1.6 -0.9 0.4 1.6 2.0 0.6 1.8 1.2
Waist circumference 0.2 0.6 2.5 0.2 -0.5 0.5 1.6 0.7 0.4 0.7 0.7
Number of incorrect matches in round 0.2 0.3 1.0 0.3 0.1 -0.9 -0.1 1.0 -0.3 0.5 0.2
Past tobacco smoking 2.6 4.7 13.7 -2.6 -0.6 -2.2 -1.6 -1.3 -1.8 -3.7 -2.1
Alcohol usually taken with meals 0.3 0.5 1.6 0.4 -0.4 1.1 -1.3 0.6 -0.4 0.7 0.1
Nervous feelings 0.4 0.7 1.5 0.8 0.4 0.3 1.2 0.6 1.2 1.0 0.4
Frequency of tenseness / restlessness in last 2 weeks 0.6 1.0 2.6 0.8 0.9 -0.5 1.5 0.1 1.6 1.2 0.3
Hearing difficulty/problems with background noise 0.4 0.7 2.3 0.1 0.3 -1.4 -0.5 1.5 -0.7 0.5 0.3
Hair/balding pattern: Pattern 2 1.6 2.0 5.1 -0.6 1.0 -1.7 1.0 -2.1 -2.3 -1.1 0.1
Had menopause 0.4 0.5 1.7 -1.3 -0.5 0.9 -0.3 -0.0 -0.5 -0.6 -0.9
Had other major operations 0.2 0.3 1.2 0.2 0.4 0.6 -0.3 -0.0 -1.1 0.0 0.4
Forced vital capacity (FVC) 1.0 3.9 7.5 -2.1 -1.2 -2.7 -1.9 -1.9 -2.3 -1.6 -1.7
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.5 5.1 2.3 0.4 -1.2 0.1 1.6 0.5 0.0 1.6
Ever unenthusiastic/disinterested for a whole week 1.5 1.8 3.8 1.0 -0.3 -1.8 -0.2 1.9 -0.1 2.0 1.6
Qualifications: None of the above 0.2 0.5 1.7 0.0 -1.2 -0.0 1.3 -0.2 -0.6 0.4 -0.5
Financial difficulties in last 2 years 0.6 0.7 1.8 -1.3 0.8 -0.9 -0.4 -1.3 0.2 -0.3 -0.8
Mouth/teeth dental problems 0.2 0.2 1.2 -0.2 0.4 0.3 0.3 -1.1 0.3 0.0 -0.4
Heart attack 0.9 1.2 3.1 -1.4 -0.6 -0.8 -1.2 0.5 -0.9 -1.8 -0.7
Allergy 0.4 0.9 3.0 -1.1 0.3 -1.7 -1.4 -0.4 0.1 -0.6 -0.7
Pain all over the body in last month 0.3 0.4 1.5 -0.5 -0.4 0.2 0.1 1.2 -0.7 -0.4 -0.7
Diabetes (self-reported) 1.6 2.4 8.5 0.8 -0.8 2.9 -0.4 0.5 2.0 1.6 1.6
Hayfever/allergic rhinitis (self-reported) 1.9 2.6 6.3 -1.1 2.3 1.4 -1.0 -2.5 -1.1 -1.6 -1.0
Medication: Ramipril 0.9 1.1 2.1 -0.9 -0.8 1.5 -0.2 -1.4 -1.3 -1.4 -0.2
Medication: Simvastatin 0.8 1.2 2.9 -0.1 1.3 1.7 1.7 -1.3 0.6 0.1 0.5
Fluid intelligence score 0.6 1.3 3.2 -1.1 -1.8 0.1 -0.3 -1.1 -1.6 -0.4 -1.3
Illnesses of siblings 0.7 0.9 3.6 -0.2 1.2 -1.9 1.0 0.9 0.2 -0.3 -0.6
Neuroticism score 1.3 2.7 5.1 1.7 1.4 -1.7 1.0 2.2 0.5 2.3 1.5
Weight 0.1 0.4 1.6 -0.2 -1.3 -0.4 0.4 0.9 0.0 0.4 0.4
Impedance of arm (right) 0.3 1.5 4.2 1.9 -0.5 2.0 0.2 0.9 0.2 1.6 0.2
Arm fat percentage (right) 0.2 0.8 2.0 1.0 0.1 0.7 1.4 1.3 0.1 0.7 0.8
Trunk fat-free mass 0.2 1.2 4.1 -2.0 -1.2 -1.2 -1.3 0.2 -0.5 -0.9 -0.6
Hip circumference 0.1 0.3 0.8 -0.1 -0.1 -0.8 0.3 0.9 -0.4 0.6 0.3
Time employed in main current job 0.4 0.5 1.2 0.9 -0.4 0.6 -1.1 0.5 -0.8 0.7 0.0
Alcohol intake versus 10 years previously 0.2 0.2 1.0 0.4 1.0 -0.7 0.1 0.2 0.4 -0.2 0.2
Father’s age at death 1.0 1.4 7.0 0.2 -1.3 0.4 0.4 2.6 1.1 0.0 0.8
Worrier / anxious feelings 0.6 1.1 3.1 0.5 1.8 -1.7 0.2 0.9 0.6 1.1 0.3
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 3.1 1.2 0.7 -0.5 1.6 -0.1 -0.4 1.8 0.7
Falls in the last year 0.6 0.8 4.5 -0.5 -2.1 0.6 -0.9 -0.4 0.0 -0.2 -0.1
Hair/balding pattern: Pattern 3 0.5 0.8 2.9 0.9 -0.5 0.1 0.7 1.7 0.3 1.2 0.2
Number of live births 0.4 0.5 1.2 -1.1 -0.9 0.1 0.3 1.0 0.7 -0.7 -0.6
Forced expiratory volume in 1-second (FEV1) 1.7 5.7 10.5 -1.7 -2.2 -3.2 -2.7 -1.9 -3.2 -1.9 -1.7
Pulse rate 0.9 1.4 3.8 -1.4 -0.7 -1.2 -0.4 0.7 -2.0 -1.2 -1.3
Happiness 0.3 0.4 2.6 -0.3 0.3 -1.6 -0.2 0.2 -0.5 -0.0 -0.3
Noisy workplace 0.3 0.4 0.6 0.5 -0.6 0.8 -0.4 0.4 0.8 0.8 0.2
Qualifications: A levels/AS levels or equivalent 0.4 1.0 3.1 -0.9 0.1 0.7 -1.1 0.7 -1.2 -1.8 -0.1
Serious illness, injury or assault of a close relative in last 2 years 0.8 0.9 2.5 1.1 0.4 0.6 1.6 -0.8 0.9 1.2 0.6
Mouth/teeth dental problems: Dentures 0.4 0.7 2.0 0.5 -0.7 0.6 1.4 0.4 0.6 1.1 1.0
Asthma 0.2 0.3 1.7 0.4 0.4 0.5 0.2 1.3 0.4 0.2 0.4
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 1.4 1.2 0.8 -0.1 0.6 0.4 0.6 1.1 1.2
Medication: Cholesterol lowering 0.2 0.4 1.1 0.1 0.9 0.4 0.6 -0.6 1.0 0.1 0.3
Depression (self-reported) 1.1 1.3 5.5 0.9 1.2 -2.4 0.7 0.7 0.8 1.0 0.0
Medication: Lansoprazole 0.4 0.5 1.1 -0.9 0.1 1.0 -0.8 -0.8 -0.7 -0.3 -0.5
Prospective memory result 1.4 1.7 4.5 0.9 1.7 0.5 0.1 2.1 1.8 0.7 1.2
Lung cancer (father) 0.8 0.9 3.5 0.3 0.7 -1.3 1.9 -0.1 -1.2 0.4 -0.2
Illnesses of mother 1.4 1.8 4.6 -2.1 -1.2 -1.3 1.0 0.1 -1.3 -1.6 -1.0
Forced expiratory volume in 1-second (FEV1), Best measure 1.0 3.3 9.5 -1.5 -1.5 -3.1 -1.4 -1.6 -2.2 -1.4 -1.2
Pulse wave Arterial Stiffness index 0.6 0.6 1.6 0.3 -0.1 0.6 1.3 -1.1 1.2 -0.2 0.7
Impedance of arm (left) 0.3 1.6 4.7 2.2 -1.1 2.0 0.5 0.4 -0.1 1.6 0.2
Arm fat mass (right) 0.1 0.5 1.4 0.5 -0.3 0.2 1.1 1.2 0.2 0.7 0.8
Trunk predicted mass 0.2 1.3 4.4 -2.1 -1.3 -1.1 -1.3 0.1 -0.5 -0.9 -0.6
Standing height 0.3 2.5 13.5 -0.6 -3.7 -0.3 -1.8 1.3 -0.3 0.9 -0.4
Length of working week for main job 0.6 0.7 2.2 -0.6 0.2 0.1 1.0 1.2 0.5 -0.1 -1.5
Exposure to tobacco smoke at home 2.7 3.0 7.2 1.5 0.7 -0.9 2.7 0.9 2.3 2.2 1.5
Breastfed as a baby 0.7 0.9 2.9 -1.2 -1.7 -0.7 0.1 -0.8 -0.2 -1.2 -0.3
Tense / ‘highly strung’ 0.2 0.3 0.6 0.7 0.8 -0.2 0.1 0.7 0.3 0.5 -0.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.3 2.6 1.6 0.9 -0.8 1.3 0.0 0.8 1.6 1.2
Hair/balding pattern: Pattern 4 0.4 0.9 3.4 0.2 -1.9 -0.9 -0.2 1.0 -1.3 0.4 0.1
Birth weight of first child 2.6 4.7 16.3 2.4 1.8 -1.6 -0.4 4.0 0.4 2.6 1.8
Peak expiratory flow (PEF) 1.7 4.0 7.5 -0.9 -2.0 -1.4 -2.6 -2.6 -2.7 -1.8 -1.1
Pulse wave reflection index 2.0 2.4 6.2 1.9 1.4 0.6 1.4 -0.4 2.5 1.6 1.7
Ever highly irritable/argumentative for 2 days 0.8 0.9 3.5 -0.4 -0.5 -1.9 -0.4 1.0 0.3 1.3 -0.7
Loud music exposure frequency 1.0 1.1 3.3 -0.8 -1.5 -0.3 0.5 1.2 -1.8 -0.7 -0.1
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 1.2 0.5 0.9 0.6 -0.7 1.1 1.1 -0.1 0.9
Mouth/teeth dental problems: Bleeding gums 0.8 1.0 2.1 1.1 1.0 1.2 0.1 1.5 0.8 0.6 1.2
Blood clot in the leg (DVT) 2.2 2.8 6.9 2.3 1.2 -0.1 1.3 0.6 0.8 2.6 2.5
Medication: Paracetamol 0.2 0.3 2.0 -0.1 -0.5 -0.3 0.1 1.4 -0.6 0.2 0.2
Headache pain in last month 0.6 1.1 3.5 -0.7 -0.3 -1.9 -1.3 0.2 0.8 0.1 -1.4
Medication for cholesterol, blood pressure or diabetes 0.1 0.1 0.4 0.4 0.1 -0.2 -0.6 0.4 0.1 -0.1 -0.4
Glaucoma (self-reported) 0.4 0.5 1.3 0.4 -1.1 -0.3 -1.1 0.6 -0.3 0.7 0.0
Gout (self-reported) 0.2 0.3 1.5 -0.3 -0.6 -0.6 0.5 -0.1 1.2 0.2 0.1
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 1.4 0.7 -1.2 -0.0 0.6 -0.1 0.8 0.9 0.5
Medication: Amlodipine 0.4 0.6 2.1 -0.1 -1.0 1.4 -0.0 -0.7 1.1 -0.0 0.5
Medication: Ventolin 100micrograms inhaler 0.7 0.9 3.5 -0.1 1.4 0.9 -0.3 1.9 0.8 0.4 0.6
Birth weight 0.7 1.4 5.8 -1.0 0.6 -1.5 -2.4 0.3 -0.4 -1.4 -0.1
Chronic bronchitis/emphysema (mother) 0.5 0.6 1.1 -0.7 0.2 -1.0 -0.9 -1.0 -0.7 -0.9 -0.8
High blood pressure (siblings) 0.8 1.2 3.8 -0.9 -0.1 1.0 -1.5 -1.9 -0.4 -1.3 0.1
Forced vital capacity (FVC), Best measure 0.6 2.3 7.3 -1.8 -0.8 -2.7 -1.0 -1.5 -0.8 -1.3 -1.4
Body fat percentage 0.7 2.6 5.0 2.2 -0.5 0.8 2.1 1.8 0.6 2.0 1.6
Leg fat percentage (right) 0.8 2.9 5.2 2.3 0.1 0.6 2.2 2.1 0.3 2.1 1.9
Arm fat-free mass (right) 0.1 0.7 2.1 -1.1 -1.5 -1.2 -0.3 0.4 0.1 -0.0 0.2
Exposure to tobacco smoke outside home 1.4 1.9 3.3 1.6 1.5 -0.7 1.8 -0.3 1.5 1.8 0.9
Comparative body size at age 10 0.5 1.4 3.6 1.5 1.9 -0.2 -0.1 1.5 0.4 0.3 1.8
Number of full brothers 0.4 0.5 2.8 0.6 -0.8 0.1 0.1 1.7 0.5 0.1 0.6
Worry too long after embarrassment 0.7 1.2 3.0 0.7 1.2 -0.4 0.6 1.6 1.1 1.7 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.3 4.1 -1.0 0.6 -2.0 -0.4 0.5 -0.5 -1.0 -1.7
Wheeze or whistling in the chest in last year 0.3 0.6 2.1 0.6 -0.0 -0.3 -0.0 1.5 1.1 0.7 0.8
Number of children fathered 0.9 1.0 3.8 0.8 2.0 -0.4 1.0 0.6 1.2 0.3 0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.1 2.9 1.0 -0.5 -0.6 1.7 1.6 -0.7 0.8 0.8
Age at first live birth 0.2 0.4 1.4 0.1 1.2 0.1 -0.6 -0.5 1.1 0.4 -0.0
Pulse wave peak to peak time 0.6 0.7 2.2 -0.3 -0.4 -0.5 -1.5 1.1 -1.3 0.2 -0.6
Health satisfaction 0.3 0.3 1.1 0.1 -0.3 -1.0 0.6 0.7 -0.4 0.5 -0.5
Shortness of breath walking on level ground 0.8 0.9 3.9 0.4 -1.4 0.3 2.0 1.0 0.3 0.1 0.0
Qualifications: College or University degree 0.4 1.3 3.5 -1.4 1.9 -0.6 -1.0 0.0 0.3 -1.7 0.2
Eye problems/disorders: None of the above 0.6 0.7 2.6 0.2 1.2 -0.1 0.9 1.6 0.4 -0.7 0.1
Mouth/teeth dental problems: Loose teeth 0.5 0.6 2.6 -0.2 0.5 -0.6 -1.6 1.0 -0.8 -0.2 -0.3
Emphysema/chronic bronchitis 0.4 0.4 1.1 0.3 -1.1 0.7 0.3 0.6 -0.3 -0.3 1.1
Medication for pain relief, constipation, heartburn 0.8 1.4 3.0 1.1 1.6 1.4 0.3 0.7 1.7 1.1 0.9
Neck or shoulder pain in last month 0.8 1.1 3.5 0.6 -1.1 -1.5 0.4 -1.9 0.7 1.0 0.3
Medication: Blood pressure 0.2 0.3 0.8 -0.7 -0.9 0.3 0.5 -0.6 -0.3 -0.4 0.5
Angina (self-reported) 0.3 0.3 1.1 0.3 -0.5 1.1 0.2 0.1 0.7 0.8 -0.4
Migraine (self-reported) 0.8 1.0 2.0 1.1 0.6 -0.6 0.0 0.2 1.4 1.4 1.2
Medication: Ibuprofen 0.9 1.0 3.3 1.3 0.9 -0.3 0.8 0.5 0.2 1.2 1.8
Medication: Allopurinol 1.0 1.3 6.9 0.5 -0.1 0.1 0.7 0.5 2.6 1.1 1.1
Medication: Omeprazole 1.6 1.9 3.7 -1.6 0.2 -1.9 -1.2 -0.4 -1.4 -1.5 -1.9
Medication: Seretide 50 evohaler 0.7 0.9 5.5 0.3 0.5 0.3 0.8 2.4 -0.2 0.2 -0.4
Mean time to correctly identify matches 0.4 0.8 1.3 -0.2 -1.1 -1.1 -0.8 1.1 -0.8 1.1 -0.3
Heart disease (mother) 0.9 1.1 2.6 1.3 1.0 0.6 -0.6 0.1 1.6 1.6 0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 2.5 0.6 -0.8 1.6 -0.2 -0.3 0.1 0.4 -0.6
Whole body fat mass 0.4 1.5 3.0 1.3 -0.8 0.4 1.4 1.7 0.5 1.6 1.2
Leg fat mass (right) 0.4 1.6 3.5 1.3 -0.8 0.1 1.7 1.9 0.3 1.5 1.3
Arm predicted mass (right) 0.1 0.5 1.4 -1.0 -1.2 -1.1 -0.6 0.3 0.2 0.2 0.1
Pulse rate, automated reading 0.7 2.3 6.3 -1.1 -0.0 -1.3 -2.3 0.3 -2.5 -1.0 -1.6
Alcohol intake frequency. 0.2 0.6 2.1 -0.4 -0.6 -1.5 -0.9 -0.2 -0.7 -0.3 -0.6
Comparative height size at age 10 0.5 2.7 10.8 -1.8 -3.3 0.0 -1.8 -0.8 -1.5 -0.2 -1.2
Number of full sisters 0.8 1.0 2.1 -0.5 1.4 -1.3 -0.2 -1.2 -0.1 -1.4 0.3
Suffer from ‘nerves’ 0.8 1.3 3.9 1.1 1.0 -2.0 1.0 0.9 0.2 1.2 0.8
Overall health rating 0.3 0.6 2.0 -1.1 -0.3 -0.6 -0.3 -0.5 -1.4 -0.5 -0.9
Chest pain or discomfort 0.3 0.5 2.9 0.1 0.4 -0.2 -0.1 -0.8 -1.7 0.3 0.1
Had major operations 0.9 1.0 4.4 -0.3 -0.9 -2.1 0.8 0.2 0.3 0.3 -1.4
Age at last live birth 0.8 1.1 3.5 -0.6 1.9 0.9 -1.3 -0.7 1.4 -0.5 -0.3
Family relationship satisfaction 1.3 1.6 4.6 2.1 0.2 1.2 0.5 1.0 0.5 1.5 1.6
Leg pain on walking 1.2 1.5 3.5 0.9 0.8 0.6 1.9 1.9 1.1 1.2 1.0
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.5 1.1 -0.3 -0.8 0.9 -0.0 -1.0 -0.5 -1.0 -0.5
Commuting to job workplace: Car/motor vehicle 0.2 0.3 0.6 -0.4 0.8 0.6 0.1 -0.8 0.4 -0.4 -0.2
Illness, injury, bereavement, stress in last 2 years 1.0 1.2 5.6 1.0 -0.0 0.9 -0.9 2.4 0.2 0.0 1.1
Medication: Aspirin 0.3 0.5 1.7 -0.8 -0.9 -0.1 0.3 -1.3 0.5 -0.4 -0.2
Supplements: Vitamin C 0.2 0.2 0.8 -0.1 0.4 0.2 -0.9 -0.9 -0.0 -0.4 0.2
Knee pain experienced in last month 1.5 2.4 9.6 -1.7 -0.1 -3.1 -0.3 -1.7 -0.7 -1.3 -1.2
Hypertension (Self-reported) 0.6 1.8 3.7 -1.5 -1.7 0.3 -1.2 -1.9 -1.1 -1.6 -0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.8 -0.4 1.3 0.4 -0.4 -0.2 0.7 -0.9 -0.4
Illnesses of father: Heart disease 0.3 0.4 1.1 0.7 0.9 -0.3 0.0 0.5 1.1 0.4 0.6
Illnesses of siblings: Diabetes 2.8 3.4 5.5 -2.3 -1.0 -1.1 -1.8 -2.1 -1.9 -2.1 -2.0
Smoking status: Previous 2.1 3.1 9.8 2.3 0.8 1.3 1.1 1.0 1.0 3.1 2.0
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.6 2.6 -0.4 -1.0 -1.6 -0.7 -0.2 0.5 0.4 -0.7
Whole body fat-free mass 0.2 1.2 3.8 -1.9 -1.3 -1.3 -1.0 0.2 -0.3 -0.8 -0.7
Leg fat-free mass (right) 0.2 1.0 2.7 -1.6 -1.2 -1.4 -0.7 0.2 -0.0 -0.6 -0.6
Arm fat percentage (left) 0.2 1.0 3.1 1.2 -0.3 0.7 1.8 1.1 0.2 0.7 0.9
Average weekly red wine intake 0.6 0.9 6.0 0.1 0.4 2.4 -0.2 0.3 -0.0 0.4 0.9
Handedness (chirality/laterality): Left-handed 0.5 0.6 2.0 -0.3 1.4 -0.9 0.7 0.1 0.9 -0.5 -0.2
Mood swings 3.0 5.4 12.8 2.9 0.7 -1.8 2.6 2.1 1.3 3.6 2.4
Loneliness, isolation 0.4 0.6 2.0 1.0 -0.5 -0.4 0.6 -0.7 -0.3 0.3 1.4
Long-standing illness, disability or infirmity 0.9 1.4 4.0 -1.4 -2.0 -1.4 -1.0 -0.8 -0.3 -0.2 -1.2
Ever had bowel cancer screening 0.9 1.1 5.6 -0.2 1.2 -0.0 -1.0 2.4 0.7 0.4 0.0
Diabetes diagnosed by doctor 0.9 1.4 7.9 -0.2 -0.8 2.8 -0.8 0.3 1.1 0.2 0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.9 1.8 0.4 0.8 -0.4 1.3 -1.2 1.4 0.6 0.9
Friendships satisfaction 0.7 0.9 3.2 1.0 0.1 -1.3 0.0 1.8 0.5 0.9 0.4
Qualifications: nursing, teaching 0.4 0.7 1.9 -0.1 0.7 -1.1 -0.5 1.4 -1.2 -0.5 0.3
Commuting to job workplace: Walk 0.2 0.2 0.7 0.3 -0.5 0.5 -0.7 -0.0 -0.0 0.2 0.8
Eye problems/disorders: Cataract 0.3 0.4 1.7 0.1 0.4 -1.3 -0.6 -0.7 0.0 0.6 -0.1
Mouth/teeth dental problems: Mouth ulcers 1.0 1.6 5.7 1.2 -0.5 -1.5 -0.9 2.4 0.1 1.2 0.9
Medication for cholesterol 1.2 1.9 4.5 1.1 0.2 0.1 1.8 2.1 1.8 1.5 0.7
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.3 1.7 -0.3 0.1 -0.5 -0.6 0.3 -1.3 -0.3 0.2
Back pain experienced in last month 0.6 0.8 3.3 0.7 -0.2 0.4 0.8 -0.2 1.8 1.1 0.7
Mineral and other dietary supplements 1.2 1.6 3.5 1.9 -0.1 1.5 0.6 0.6 0.1 1.8 1.6
Breast cancer (self-reported) 0.6 0.7 5.0 0.2 0.3 -0.0 -0.0 0.6 -2.2 0.3 0.2
Asthma (self-reported) 0.1 0.3 1.4 0.3 0.4 0.4 -0.0 1.2 0.5 0.0 0.0
Osteoporosis (self-reported) 1.5 1.8 4.1 1.5 0.3 0.7 2.0 0.8 0.5 2.0 1.7
Osteoarthritis (self-reported) 1.0 1.4 5.6 -0.5 -0.2 -2.4 -0.1 -0.6 -2.0 -0.5 -0.6
Medication: Aspirin 0.3 0.4 1.7 -0.8 -0.4 -0.3 0.4 -1.3 0.3 -0.2 -0.2
Medication: Gliclazide 0.3 0.3 1.1 0.4 0.1 0.7 -1.1 -0.0 0.0 0.8 0.3
Illnesses of father: None of the above (group 1) 0.7 0.9 3.9 0.1 -2.0 -0.4 -0.7 0.3 -1.4 0.6 -0.4
Smoking status: Current 0.6 0.9 2.1 1.0 -0.4 0.6 1.3 -0.8 -0.1 1.4 1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 2.9 6.1 11.0 -2.8 -2.1 -2.1 -2.4 -2.7 -1.9 -3.3 -2.1
Whole body water mass 0.2 1.0 3.5 -1.9 -1.2 -1.2 -0.9 0.2 -0.2 -0.8 -0.6
Leg predicted mass (right) 0.2 1.0 2.6 -1.6 -1.3 -1.5 -0.7 0.2 -0.1 -0.6 -0.6
Arm fat mass (left) 0.2 0.8 2.5 0.7 -0.6 0.3 1.6 1.2 0.4 0.8 1.0
Number of self-reported non-cancer illnesses 0.4 0.7 2.5 -0.6 -1.0 -0.8 0.4 -1.6 -0.7 -0.4 0.1
Average weekly champagne plus white wine intake 0.4 0.6 2.2 0.8 0.6 1.5 0.1 -0.4 0.2 0.8 0.6
Miserableness 2.3 3.9 7.4 2.0 1.7 -0.9 1.1 2.3 2.2 2.7 2.2
Guilty feelings 0.7 1.1 2.8 0.5 1.3 -0.2 0.0 1.7 -1.4 -0.5 1.4
Wears glasses or contact lenses 0.2 0.2 0.9 0.5 -0.5 0.1 0.2 -0.5 -0.9 0.6 0.2
Ever taken oral contraceptive pill 0.1 0.1 0.6 0.0 -0.2 -0.8 -0.1 0.4 -0.1 -0.2 0.3
Hearing aid user 1.2 1.4 3.7 0.9 1.4 -0.6 1.2 1.9 0.8 1.2 1.0
Mother’s age at death 0.4 0.5 2.0 0.5 1.2 -1.4 -0.1 0.1 -0.7 0.1 -0.0
Financial situation satisfaction 0.4 0.5 3.0 -0.0 0.3 -0.4 0.1 -1.7 -0.5 0.1 0.5
Tinnitus: Yes, now most or all of the time 2.1 2.5 6.3 1.4 0.1 0.4 0.1 2.5 -2.1 1.4 2.2
Commuting to job workplace: Public transport 0.6 0.8 1.8 -0.6 -0.9 -0.7 -1.3 -0.4 -1.3 -0.4 -0.7
Eye problems/disorders: Glaucoma 0.9 1.1 3.9 1.4 -0.1 0.6 0.9 0.3 0.1 2.0 1.2
Medication: Blood pressure 1.6 3.0 5.1 -2.3 -0.9 -0.1 -2.1 -2.1 -1.9 -2.1 -1.3
Pain type(s) experienced in last month: Hip pain 1.7 2.2 7.5 -1.5 -0.6 -2.7 -0.3 -1.1 -1.0 -1.4 -1.9
Supplements: Fish oil (including cod liver oil) 0.1 0.1 0.4 -0.3 0.2 -0.4 0.2 0.2 0.5 -0.2 -0.6
High cholesterol (Self-reported) 1.0 1.7 4.5 -1.2 -1.2 1.3 0.9 -2.1 -0.5 -1.8 -0.5
Medication: Bendroflumethiazide 1.4 2.1 5.9 -1.9 -0.0 0.3 -0.7 -0.3 -2.3 -2.4 -1.3
Medication: Paracetamol 0.4 0.6 2.2 0.5 -0.0 0.2 0.8 1.5 -0.7 0.8 0.9
Medication: Lisinopril 0.7 0.9 2.7 -1.2 0.5 -1.1 0.2 -1.6 -0.3 -0.6 -1.1
Medication: Atorvastatin 0.6 0.7 2.2 -0.4 -1.5 1.0 -1.1 -0.7 -0.8 -0.3 -0.2
Illnesses of father: High blood pressure 0.2 0.3 1.4 -0.5 1.2 -0.0 0.1 0.4 0.4 -0.3 0.3
Alcohol drinker status: Never 0.4 0.4 1.7 0.3 -0.6 0.6 0.1 1.3 -0.7 -0.6 -0.4
Ever smoked 2.8 4.8 12.2 2.4 1.3 2.5 1.5 1.2 2.1 3.5 2.2
Basal metabolic rate 0.1 0.6 1.6 -1.3 -1.2 -1.1 -0.5 0.4 -0.1 -0.3 -0.2
Leg fat percentage (left) 1.0 3.5 6.2 2.5 0.2 0.8 2.1 2.2 0.8 2.4 2.3
Arm fat-free mass (left) 0.1 0.4 0.9 -0.9 -0.9 -0.9 -0.4 0.6 0.3 0.3 0.3
Number of operations (self-reported) 0.4 0.6 2.8 0.8 -0.7 -1.7 0.5 -0.1 -0.5 0.6 -0.1
Average weekly beer plus cider intake 1.7 2.5 5.4 1.8 -0.1 1.6 1.9 0.8 1.7 2.3 1.2
Irritability 0.5 0.9 2.4 0.6 0.2 -0.9 0.3 1.0 -0.5 1.5 1.6
Risk taking 0.3 0.5 1.6 -0.2 0.1 -0.8 1.3 -0.1 -0.9 -0.5 0.7
Ever had prostate specific antigen (PSA) test 0.4 0.4 1.2 -0.7 0.3 1.1 -1.1 0.4 -0.3 -0.5 -0.2
Fractured/broken bones in last 5 years 1.0 1.3 2.9 1.1 -1.7 -0.9 1.2 1.1 0.5 1.6 0.1
Age started oral contraceptive pill 1.8 2.2 4.0 -1.7 -1.7 0.6 -1.7 -1.4 -0.4 -2.0 -1.6
Diastolic blood pressure, automated reading 0.9 2.7 12.2 -1.6 -0.7 -0.4 -3.5 0.5 -1.2 -1.6 -1.2
Ever depressed for a whole week 1.6 2.0 10.1 -0.0 -0.8 -3.2 -0.8 1.1 -1.2 1.3 0.4
Unable to work because of sickness or disability 0.5 0.6 2.5 -0.6 -0.7 -0.6 0.5 -1.6 -0.4 0.8 -0.4
Commuting to job workplace: Cycle 0.3 0.4 1.2 -0.5 -0.1 1.1 -1.0 0.6 0.7 -0.0 0.1
Myopia 0.1 0.2 0.5 -0.3 0.7 0.1 0.5 -0.3 0.7 -0.3 0.3
Vascular/heart problems diagnosed by doctor 0.8 2.3 4.3 2.0 1.3 -0.6 1.4 2.1 1.5 2.0 0.2
Cholesterol lowering medication 0.5 0.7 2.5 -0.8 -0.5 0.9 0.9 -1.6 -0.5 -0.8 -0.2
Medication: Omeprazole (e.g. Zanprol) 1.2 1.5 2.5 -1.5 -0.9 -1.3 -1.0 -0.5 -1.4 -1.2 -1.6
Pain experienced in last month 0.4 0.7 2.9 0.4 0.3 1.7 0.3 0.5 -0.1 -0.2 1.3
Supplements: Calcium 1.0 1.1 3.1 -1.8 -0.1 -0.7 0.5 -0.7 -0.6 -1.8 -1.1
Basal cell carcinoma (self-reported) 0.5 0.6 2.1 0.4 1.2 0.7 0.4 1.5 0.0 -0.4 0.7
Heart attack/myocardial infarction (self-reported) 0.8 1.1 2.9 -1.3 -0.6 -0.9 -1.2 0.5 -0.9 -1.7 -0.7
Deep venous thrombosis (DVT) (self-reported) 2.1 2.7 6.5 2.3 1.0 -0.1 1.3 0.5 0.8 2.6 2.4
Heart disease (siblings) 0.9 1.1 3.1 0.3 -1.0 0.8 -1.4 1.2 1.8 0.6 0.1
Alcohol drinker status: Previous 0.8 0.9 2.9 -1.2 -0.6 -0.5 -1.7 -0.1 -1.1 -0.5 -1.0
Pack years of smoking 0.5 0.8 1.6 -0.5 -1.1 1.2 1.2 -0.4 -1.1 0.0 -0.8
Impedance of whole body 0.7 3.8 11.1 3.3 -0.8 2.3 1.1 1.0 0.5 3.1 1.2
Leg fat mass (left) 0.4 1.5 3.4 1.3 -0.6 0.0 1.4 1.9 0.5 1.6 1.4
Arm predicted mass (left) 0.1 0.4 1.1 -1.0 -0.9 -0.9 -0.1 0.3 0.4 0.4 0.1