TWAS hub - RPL32P3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2270	0.0480	1.5e-14	0.184	0.141	0.191	0.187	0.183	7.2e-22	8.1e-17	9.6e-23	3e-22	9.2e-22
2	GTEx	Adipose Subcutaneous	0.0940	0.0430	4.4e-03	0.026	NA	0.052	NA	0.050	2.9e-03	NA	4.0e-05	NA	5.9e-05
3	GTEx	Adrenal Gland	0.1315	0.0574	6.7e-03	0.036	NA	-0.005	NA	0.016	1.9e-02	NA	5.3e-01	NA	8.5e-02
4	GTEx	Brain Cerebellar Hemisphere	0.4240	0.1630	5.3e-03	0.008	NA	-0.006	NA	-0.009	2.0e-01	NA	4.8e-01	NA	6.7e-01
5	GTEx	Colon Transverse	0.1880	0.0820	5.2e-03	-0.004	NA	-0.004	NA	-0.003	5.5e-01	NA	6.1e-01	NA	4.8e-01
6	GTEx	Nerve Tibial	0.2323	0.0772	5.0e-05	0.019	NA	0.023	NA	0.032	1.6e-02	NA	8.8e-03	NA	2.3e-03
7	GTEx	Skin Sun Exposed Lower leg	0.1780	0.0560	5.7e-06	0.014	NA	0.040	NA	0.033	2.4e-02	NA	2.9e-04	NA	9.4e-04
8	TCGA	Breast Invasive Carcinoma	0.0195	0.0145	1.8e-03	0.009	0.013	0.011	NA	0.011	4.3e-03	7.9e-04	1.7e-03	NA	1.6e-03
9	TCGA	Brain Lower Grade Glioma	0.0341	0.0193	1.8e-04	0.041	0.028	0.034	NA	0.037	1.6e-05	3.2e-04	8.7e-05	NA	4.5e-05
10	TCGA	Lung Adenocarcinoma	0.0653	0.0395	1.0e-03	0.002	0.015	-0.002	NA	-0.002	1.6e-01	6.4e-03	6.7e-01	NA	5.6e-01
11	TCGA	Prostate Adenocarcinoma	0.0386	0.0235	4.1e-04	0.032	0.032	0.022	NA	0.028	2.5e-04	2.4e-04	1.9e-03	NA	6.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Waist Hip Ratio (WHR)	9.9	44.5	151.3	-5.2	1.7	5.4	1.9	12.3	5.8	-1.0	5.7	6.9	10.1	7.6
Number of children fathered	5.0	5.7	12.1	-0.1	-2.6	-2.7	-0.9	-3.5	-2.1	-1.8	-2.8	-2.4	-2.7	-2.7
Hearing aid user	4.3	4.9	9.5	0.3	-2.2	-2.1	-1.7	-1.7	-2.6	-0.6	-2.7	-2.4	-3.1	-2.9
Severe depression (siblings)	4.0	4.5	8.6	-0.6	1.7	2.4	1.6	1.9	2.9	0.8	2.8	2.3	2.2	2.5
Comparative body size at age 10	3.4	9.5	19.1	-1.7	-4.4	-3.4	-3.1	-1.8	-3.2	-4.3	-3.2	-2.5	-2.2	-2.8
Frequency of tenseness / restlessness in last 2 weeks	3.1	4.9	10.9	-0.7	1.7	1.9	1.7	2.8	2.3	0.6	2.0	2.7	3.3	2.9
Ever had bowel cancer screening	3.0	3.5	7.9	-1.2	-1.4	-2.4	-2.8	-2.5	-2.0	-1.4	-1.7	-1.0	-1.3	-1.9
Ever taken oral contraceptive pill	3.0	3.4	7.2	-1.7	0.5	2.2	1.4	2.7	1.6	-0.3	1.8	1.8	2.5	2.0
Supplements: Zinc	2.9	3.2	6.5	1.8	0.4	-2.1	-2.3	-1.2	-2.1	0.4	-2.2	-2.5	-1.2	-1.8
Body Mass Index (BMI) (2010)	2.8	3.8	7.9	1.2	-1.1	-1.7	-1.4	-0.6	-1.9	0.1	-2.8	-2.8	-2.8	-2.6
Hip circumference	2.7	11.8	45.8	0.2	-3.7	-3.3	-0.6	-6.8	-2.4	-1.8	-2.3	-2.4	-5.4	-3.1
Forced expiratory volume in 1-second (FEV1), predicted	2.7	5.6	13.7	0.7	1.5	3.4	3.7	1.9	2.9	2.0	2.9	1.7	0.3	2.6
Wears glasses or contact lenses	2.6	3.0	5.4	-0.3	-1.6	-2.1	-2.0	-1.1	-2.3	-2.0	-1.8	-1.7	-1.4	-1.9
LDL Cholesterol	2.4	3.9	9.3	0.2	1.7	3.0	1.4	3.0	2.1	1.6	2.1	1.7	1.3	1.9
Neuroticism	2.4	5.7	11.4	-2.2	0.8	2.1	0.5	2.8	2.4	-0.9	2.8	2.9	3.1	3.4
Ever had hysterectomy (womb removed)	2.4	2.7	4.5	0.6	-0.8	-2.0	-1.8	-1.4	-1.3	-1.2	-2.0	-1.9	-1.9	-2.1
Myopia	2.4	3.5	6.5	-0.6	1.1	2.5	2.3	2.2	2.0	-0.1	2.0	1.8	1.7	2.4
Glaucoma (self-reported)	2.3	2.7	6.7	-0.3	1.6	2.6	1.7	-0.1	2.4	1.6	1.7	1.6	1.2	1.6
Miserableness	2.3	4.0	8.6	-1.5	0.2	2.4	1.6	2.9	1.6	0.2	2.4	2.5	2.1	2.4
Irritability	2.3	3.8	6.5	-2.5	-0.5	1.9	0.6	2.3	1.9	-1.7	1.9	2.5	2.3	2.1
Leg fat percentage (right)	2.2	7.9	18.1	-0.6	-2.8	-4.2	-2.9	-2.8	-3.4	-2.9	-2.9	-2.0	-2.1	-2.6
Neuroticism score	2.1	4.4	8.9	-1.1	1.0	2.2	1.1	3.0	2.9	-0.3	2.4	2.3	2.4	2.4
Breast cancer (self-reported)	2.1	2.5	8.8	1.6	0.3	-1.6	-1.7	-3.0	-1.2	0.1	-1.6	-1.6	-1.5	-1.2
Leg fat percentage (left)	2.1	7.7	17.7	-1.3	-3.1	-4.2	-2.8	-3.0	-3.2	-3.2	-2.6	-1.6	-1.8	-2.3
Mother’s age at death	2.0	2.5	5.4	1.6	0.0	-1.4	-0.9	-2.3	-0.9	0.1	-2.1	-2.2	-1.6	-2.1
Alcohol drinker status: Previous	2.0	2.3	5.2	-0.0	1.7	1.6	-0.3	2.3	1.9	0.4	2.1	1.5	1.1	1.7
Rheumatoid Arthritis	1.9	2.6	5.7	1.0	2.2	1.6	1.1	1.4	1.3	2.4	1.1	0.9	2.2	1.7
Qualifications: None of the above	1.9	4.2	8.2	-0.1	-1.7	-2.5	-2.9	-2.1	-2.4	-1.1	-2.3	-1.8	-1.8	-2.2
Noisy workplace	1.9	2.3	6.8	-2.1	-2.6	-1.2	-1.4	-1.3	-0.9	-2.4	-1.4	-0.5	-0.4	-0.4
Loud music exposure frequency	1.9	2.1	9.7	-1.1	-2.2	-0.7	-0.7	-1.1	-0.9	-3.1	-1.4	-0.6	-0.8	-1.1
Bipolar Disorder (2018)	1.8	2.8	6.0	-1.2	-1.1	-2.2	-2.5	-1.6	-2.2	-1.3	-1.9	-1.4	-0.3	-1.6
Alzheimer’s Disease (in father)	1.8	2.0	4.7	0.5	2.0	1.8	-0.1	0.4	1.2	2.1	2.2	1.2	0.4	1.4
Prostate Cancer	1.8	2.6	7.7	2.2	2.6	0.7	0.7	1.3	1.4	2.8	0.6	0.0	1.7	1.2
Lung FVC	1.8	9.0	17.6	0.1	-2.8	-2.9	-1.6	-4.2	-3.5	-2.8	-3.4	-3.2	-2.8	-3.5
Pulse wave reflection index	1.8	2.2	8.2	-0.5	-1.3	-1.4	-1.2	-2.9	-1.6	-1.2	-0.9	-0.9	-1.7	-1.4
Medication: Amlodipine	1.8	2.5	5.4	-1.0	-1.8	-2.2	-2.3	-0.7	-1.9	-1.7	-1.8	-1.0	-0.3	-1.4
Illnesses of siblings: Diabetes	1.8	2.2	7.7	-2.2	-1.8	-1.8	-1.8	-0.0	-1.0	-2.8	-0.5	0.4	0.3	-0.6
Number of incorrect matches in round	1.7	2.8	7.2	2.7	1.7	-0.8	-1.0	-1.6	-1.3	1.7	-2.1	-2.5	-0.4	-1.1
Ever unenthusiastic/disinterested for a whole week	1.7	2.0	4.9	-0.1	1.4	1.8	0.3	1.2	1.3	0.2	2.2	2.0	1.4	1.9
Father’s age at death	1.7	2.3	6.6	-1.2	-0.2	2.2	2.6	1.7	1.0	0.7	1.4	1.8	1.0	1.3
Qualifications: O levels/GCSEs or equivalent	1.7	2.7	10.0	-0.2	0.5	2.0	3.2	0.8	2.4	0.9	1.5	1.3	0.9	1.7
Number of live births	1.6	2.3	6.2	0.7	-0.4	-1.2	-1.5	-1.0	-1.8	-0.2	-1.5	-1.7	-2.5	-2.1
Suffer from ‘nerves’	1.6	2.5	6.5	0.8	2.3	1.8	1.1	0.7	2.5	1.0	1.2	0.9	2.1	1.5
Supplements: Vitamin C	1.6	1.9	8.7	-1.8	-1.5	-1.7	-1.1	-0.1	-0.8	-3.0	-1.0	-0.7	-0.3	-0.9
Friendships satisfaction	1.6	2.0	4.0	-0.5	1.1	1.8	1.2	1.3	1.7	0.1	1.5	1.5	1.7	2.0
Supplements: Glucosamine	1.5	1.9	6.8	-2.0	-2.6	-1.2	-0.5	-1.6	-0.4	-1.8	-0.8	-0.8	-0.9	-0.8
Health satisfaction	1.5	2.0	4.7	-1.0	-0.2	1.6	1.7	0.7	2.2	-0.2	1.0	1.8	1.7	1.7
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	4.5	-1.3	0.3	1.8	0.8	1.3	1.3	0.7	1.4	1.2	1.5	2.1
Number of operations (self-reported)	1.5	2.2	7.5	-1.4	-2.4	-1.5	-1.6	-0.0	-0.9	-2.7	-0.7	-0.5	-1.0	-1.0
Ever depressed for a whole week	1.5	1.8	4.3	-1.0	0.6	1.1	0.6	1.2	1.2	-0.2	2.1	2.1	1.5	1.8
Triglycerides	1.4	2.2	6.0	0.7	-0.8	-1.5	-2.1	-0.4	-1.6	-0.8	-2.4	-2.1	-0.7	-1.6
Blood Eosinophil Count	1.4	10.6	50.3	3.4	2.0	1.9	7.1	3.1	-0.3	5.8	0.0	-0.5	1.8	0.6
Relative age of first facial hair	1.4	2.9	10.2	3.0	2.9	1.5	0.3	0.8	1.0	3.2	0.5	-0.4	-0.0	0.1
Hayfever/allergic rhinitis (self-reported)	1.4	1.8	4.5	1.0	1.9	1.6	1.0	1.2	0.6	2.1	1.0	0.3	1.8	1.2
Medication: Ramipril	1.4	1.8	6.1	-0.8	-1.0	-1.8	-2.5	-0.8	-1.5	-1.3	-1.7	-0.9	0.5	-0.8
Fluid intelligence score	1.4	2.9	6.9	0.4	1.5	2.6	2.1	0.6	2.2	1.8	2.1	1.7	0.4	1.6
Illnesses of siblings	1.4	1.9	6.9	1.0	1.1	1.7	2.2	0.5	1.2	2.6	1.3	0.3	0.0	0.9
Pulse wave Arterial Stiffness index	1.4	1.7	5.1	-2.3	-1.7	-1.2	-1.6	-1.0	-1.5	-1.6	-0.3	0.5	0.3	0.0
Pulse wave peak to peak time	1.4	1.7	4.1	1.9	1.4	1.4	2.0	1.0	1.8	1.4	0.6	-0.2	-0.3	0.2
Leg fat mass (right)	1.4	5.4	10.9	-0.8	-3.3	-3.0	-1.4	-2.8	-2.3	-2.8	-2.0	-1.3	-2.4	-1.9
Alcohol drinker status: Never	1.4	1.6	4.9	-1.9	-1.9	-1.5	-1.1	-0.7	-1.1	-2.2	-0.5	0.1	0.2	-0.3
Type 2 Diabetes (T2D) (2018)	1.3	2.5	9.5	0.5	1.5	1.6	0.1	3.1	1.7	1.5	1.0	0.8	2.2	1.2
Pack years adult smoking proportion	1.3	2.0	9.2	-3.0	-1.6	-0.4	-0.2	-0.0	0.1	-2.3	-0.6	0.8	1.8	0.4
Worrier / anxious feelings	1.3	2.4	6.5	-0.6	0.4	1.9	1.4	2.5	1.9	-0.1	1.7	1.6	1.7	1.6
Mouth/teeth dental problems: Mouth ulcers	1.3	2.1	3.5	-1.4	-0.3	1.6	1.0	1.7	1.3	-1.7	1.6	1.9	1.4	1.6
Mineral and other dietary supplements	1.3	1.7	5.9	1.9	2.4	1.0	-0.3	1.7	0.5	2.1	0.4	-0.1	0.5	0.7
Medication: Gliclazide	1.3	1.4	4.2	-0.3	0.4	1.5	1.0	2.1	1.4	0.1	1.1	1.3	1.5	0.9
Pack years of smoking	1.3	2.0	8.1	-2.9	-1.7	-0.7	-0.4	-0.4	-0.3	-2.6	-1.0	0.4	1.4	-0.0
Leg fat mass (left)	1.3	5.2	12.2	-1.3	-3.5	-2.9	-1.3	-2.8	-2.2	-3.0	-1.8	-0.9	-2.2	-1.6
Bipolar Disorder or Schizophrenia	1.2	2.9	7.3	0.6	0.2	-1.7	-2.1	-2.4	-1.4	0.7	-2.7	-2.4	-0.3	-1.8
Worry (Nagel 2018)	1.2	2.5	5.2	0.0	1.9	2.1	0.7	1.4	1.8	0.9	1.3	1.3	2.3	2.0
Lung FEV1/FVC ratio	1.2	6.2	10.3	-0.3	2.4	3.0	0.1	2.7	3.0	0.9	3.0	3.2	2.8	3.0
Body mass index (BMI)	1.2	5.2	11.1	-1.0	-3.3	-2.8	-1.8	-2.7	-2.3	-2.7	-2.0	-1.1	-2.2	-1.9
Hair/balding pattern: Pattern 3	1.2	1.9	3.9	1.7	-0.7	-0.9	0.2	-1.4	-0.9	0.8	-1.7	-1.8	-2.0	-1.7
Impedance of arm (left)	1.2	5.6	18.2	2.1	4.3	3.0	1.1	0.9	2.6	3.2	2.4	0.8	0.7	1.9
Shortness of breath walking on level ground	1.2	1.4	2.9	-1.3	-1.5	-1.6	-1.2	-1.2	-1.3	-1.7	-1.0	0.1	0.3	-0.5
Angina (self-reported)	1.2	1.6	5.1	-0.8	-2.2	-1.4	-1.0	-0.6	-1.3	-1.9	-1.2	-0.7	-0.4	-1.0
Medication: Allopurinol	1.2	1.6	4.9	-1.4	-2.0	-2.2	-0.9	-1.6	-1.0	-1.4	-0.4	-0.1	-0.1	-0.8
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	3.2	0.9	-0.2	-1.0	-1.0	-1.4	-1.6	0.1	-0.9	-1.6	-1.8	-1.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.5	5.2	-1.4	-0.2	0.4	0.8	1.6	1.1	-1.1	0.5	1.0	2.3	1.4
Ever smoked	1.2	2.1	5.0	-1.3	-0.7	2.2	1.1	1.8	2.0	-0.6	1.5	1.4	0.6	1.4
Risk taking	1.2	1.8	5.3	0.0	-0.9	-1.7	-2.3	-0.7	-1.2	-1.2	-2.0	-1.2	-0.1	-1.2
Major Depression (MDD)	1.1	1.3	3.1	0.0	1.1	1.8	1.2	1.1	1.0	0.1	1.1	1.1	1.6	1.4
Neuroticism (2016)	1.1	1.5	3.3	-0.3	1.3	1.3	1.1	1.5	1.4	0.1	1.1	1.1	1.8	1.5
Vitamin and mineral supplements	1.1	1.5	7.4	2.7	1.1	0.6	0.3	-0.3	-0.2	2.1	-1.0	-1.1	-0.3	-0.5
Fed-up feelings	1.1	2.1	5.4	-0.2	0.5	2.3	1.3	2.1	2.0	-0.1	1.1	1.3	1.2	1.6
Medication: Simvastatin	1.1	1.7	4.3	-2.1	-0.6	0.1	-0.1	2.0	0.5	-1.5	1.1	1.5	1.8	0.8
Impedance of arm (right)	1.1	5.2	18.1	2.0	4.3	2.9	0.7	1.4	2.5	2.9	2.4	0.8	0.7	1.9
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	2.5	0.5	1.5	1.4	0.9	1.6	1.1	1.2	0.6	0.7	1.6	0.8
Depression (self-reported)	1.1	1.4	5.2	-2.3	-1.1	-0.4	-0.4	-0.2	0.0	-2.1	0.5	1.3	1.0	0.9
Peak expiratory flow (PEF)	1.1	2.5	5.7	-0.9	-1.1	2.4	2.4	0.8	2.1	-0.7	2.0	1.7	-0.7	1.1
Headache pain in last month	1.1	1.8	7.4	0.3	1.5	1.1	0.9	2.7	-0.3	1.2	0.3	0.7	1.9	1.7
Worry too long after embarrassment	1.1	1.8	4.3	-1.7	-0.5	0.9	1.0	0.8	1.5	-1.2	1.5	2.1	1.1	1.6
Pain type(s) experienced in last month: Hip pain	1.1	1.4	4.6	-1.6	-1.3	-1.2	-2.1	-0.7	-0.6	-1.7	-1.0	-0.5	0.2	-0.3
Supplements: Fish oil (including cod liver oil)	1.1	1.4	5.0	-1.9	-2.2	-1.0	0.3	-1.6	-0.5	-1.4	-0.3	0.4	-0.8	-0.4
Depressed Affect (Nagel 2018)	1.0	2.1	5.5	-1.1	0.3	1.7	0.8	2.3	1.6	-0.7	1.6	1.6	1.3	1.7
Neuroticism (Nagel 2018)	1.0	2.4	4.6	-1.1	0.2	1.6	0.7	2.0	1.6	-0.5	1.4	2.1	2.1	2.0
Alzheimer’s Disease (including proxy)	1.0	1.5	4.3	0.8	2.1	1.5	0.2	1.0	1.3	1.6	1.4	0.8	0.6	0.6
Crohns Disease (2017)	1.0	2.2	5.7	-0.7	1.0	1.6	2.4	1.1	1.3	0.9	1.1	1.3	2.0	2.0
Mean Putamen Volume	1.0	1.1	2.4	-0.2	0.8	1.2	0.0	0.4	1.5	1.5	1.1	1.2	0.8	1.4
Fasting Glucose	1.0	1.2	3.1	0.7	-0.1	-1.1	-1.2	0.8	-1.3	0.0	-1.8	-1.5	-0.4	-1.3
BMI	1.0	5.7	13.9	-0.3	-3.7	-2.7	-1.3	-2.7	-2.5	-2.5	-1.9	-1.1	-2.9	-2.5
Hand grip strength (left)	1.0	2.6	11.2	-1.5	-1.9	1.3	3.3	-1.6	1.6	-0.5	1.0	1.5	0.2	1.2
Angina	1.0	1.3	4.6	-0.9	-2.2	-1.3	-0.7	-0.2	-1.0	-1.8	-1.1	-0.6	-0.3	-0.8
Medication: Metformin	1.0	1.5	4.3	0.6	0.1	-0.8	-2.1	1.8	-1.3	0.1	-1.7	-1.2	0.8	-0.9
Hand grip strength (right)	1.0	2.8	14.4	-1.0	-1.3	1.7	3.8	-1.0	2.2	-0.2	0.7	1.4	0.6	1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.4	2.9	-1.7	-0.7	0.4	0.4	1.4	0.4	-1.7	1.1	1.6	1.3	1.1
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	2.7	-0.7	-1.5	-0.5	-1.7	0.5	-1.0	-1.6	-1.0	-0.9	-0.8	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.2	6.5	0.5	1.1	-1.5	-2.4	-2.6	-0.8	0.4	-1.1	-1.4	-1.1	-1.6
Happiness	1.0	1.2	3.1	-1.2	-0.6	1.0	1.8	0.1	1.4	-0.9	0.7	1.1	1.3	1.2
Breastfed as a baby	1.0	1.2	4.4	0.4	-0.6	-1.4	0.3	-1.0	-1.2	-0.1	-2.1	-1.4	-0.5	-1.4
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	3.7	0.9	1.9	1.5	-0.1	1.5	1.6	1.0	1.1	0.3	-0.1	-0.0
Chronic bronchitis/emphysema (mother)	1.0	1.2	3.0	-0.6	0.0	1.4	0.2	1.7	1.4	-0.5	1.0	1.4	1.0	1.4
Migraine (self-reported)	1.0	1.2	5.5	-0.0	-0.4	-1.4	-1.3	-0.4	-2.4	-0.1	-1.2	-1.2	-0.6	-0.6
Medication: Ibuprofen	1.0	1.2	4.6	0.5	0.9	1.0	0.6	1.4	0.2	1.0	0.6	0.5	2.1	1.5
Average weekly red wine intake	1.0	1.5	4.4	-2.1	-0.2	-0.1	0.6	-0.0	0.8	-1.5	1.9	1.8	0.3	1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	7.3	-0.7	-0.2	0.1	0.2	2.7	-0.4	-1.3	-0.5	-0.2	1.1	0.4
Commuting to job workplace: Walk	1.0	1.1	4.3	-0.7	-2.1	-0.4	-0.8	-0.6	-0.8	-1.4	-0.5	0.2	-1.5	-0.8
High cholesterol (Self-reported)	1.0	1.8	4.0	-1.1	0.3	1.0	1.4	0.9	1.4	1.0	1.3	1.6	2.0	1.8
Age started oral contraceptive pill	1.0	1.3	2.7	-0.6	-0.3	-1.2	-1.6	-1.6	-1.6	-1.4	-1.2	-0.6	0.5	-0.4
Schizophrenia (2018)	0.9	1.9	4.5	1.7	1.1	-0.4	-0.7	-1.7	-0.5	2.1	-1.9	-1.9	-0.1	-1.0
Ovarian Cancer	0.9	1.2	4.7	-1.7	-1.5	-1.3	-0.7	-0.6	-0.7	-2.2	-0.4	0.2	0.6	-0.3
Standing height	0.9	8.5	33.5	-1.7	-1.6	3.5	5.8	0.1	3.9	-0.3	3.2	2.9	-1.4	2.5
Exposure to tobacco smoke at home	0.9	1.0	4.1	-2.0	-1.4	0.4	0.4	0.0	0.3	-1.4	-0.4	0.5	1.4	0.6
Mouth/teeth dental problems: Loose teeth	0.9	1.1	5.2	-0.3	-0.8	-0.9	-2.3	0.4	-1.5	-1.0	-0.7	-1.0	0.0	-0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	2.9	-1.4	-0.5	0.3	0.7	0.9	0.9	-1.4	0.7	1.7	0.3	1.0
Illnesses of father: Heart disease	0.9	1.2	5.1	0.9	-0.4	-1.7	-1.4	0.0	-0.8	-0.2	-2.2	-1.1	-0.2	-0.9
Diastolic blood pressure, automated reading	0.9	2.6	6.2	-1.3	-2.1	-1.9	-1.3	-2.2	-1.1	-2.5	-1.1	-0.6	-1.6	-1.1
Commuting to job workplace: Cycle	0.9	1.1	3.9	2.0	1.5	0.8	0.5	0.6	0.7	1.5	0.1	-0.3	-0.8	-0.7
Crohns Disease (2012)	0.8	1.2	4.6	0.0	1.2	1.0	1.4	0.9	0.5	0.7	0.6	0.9	2.1	1.3
HbA1C	0.8	0.9	3.4	-0.1	1.8	0.6	-0.5	0.9	0.3	0.4	1.1	0.8	1.4	0.9
Lupus	0.8	1.2	3.8	1.6	1.9	0.4	0.2	-1.0	-0.2	2.0	-0.5	-0.3	0.8	1.0
Average weekly spirits intake	0.8	1.0	3.1	0.5	-0.2	-1.4	-0.5	-0.1	-1.8	-0.7	-0.6	-1.1	-1.4	-1.1
Systolic blood pressure, automated reading	0.8	2.3	7.0	-0.4	-1.0	-2.0	-2.2	-2.6	-1.1	-1.3	-1.7	-1.1	-0.7	-1.1
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	3.3	0.7	0.7	-0.8	-1.8	1.2	-0.9	-0.1	-1.0	-1.1	-0.4	-0.9
Past tobacco smoking	0.8	1.5	2.5	1.6	1.5	-1.4	-0.4	-1.1	-1.2	1.5	-1.1	-1.5	-0.3	-1.2
Alcohol usually taken with meals	0.8	1.3	3.9	-0.6	-0.8	-1.8	0.1	-0.8	-0.7	-2.0	-0.6	-0.5	-1.5	-1.2
Financial difficulties in last 2 years	0.8	1.1	3.7	-1.4	-1.0	1.0	0.7	0.3	0.9	-1.9	0.8	1.1	0.7	0.7
Mouth/teeth dental problems	0.8	1.2	4.2	-0.2	-1.2	-1.4	0.9	-2.0	-1.0	0.4	-1.0	-0.9	-1.2	-0.6
Alcohol intake versus 10 years previously	0.8	1.2	3.7	-0.7	-0.7	0.8	0.6	1.9	1.0	1.0	0.3	0.9	1.8	1.3
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	10.8	-1.2	-1.9	1.9	3.3	-0.1	1.5	-1.1	1.7	1.4	-1.3	0.9
Qualifications: A levels/AS levels or equivalent	0.8	1.9	4.9	0.5	1.4	1.9	2.2	0.7	1.7	1.9	0.9	0.3	0.7	1.2
Medication: Cholesterol lowering	0.8	1.3	4.1	-1.1	0.1	0.7	0.0	1.2	0.3	0.0	1.3	1.7	2.0	1.4
Arm fat mass (right)	0.8	3.3	7.6	-0.3	-2.6	-1.9	-0.7	-2.8	-1.4	-1.9	-1.3	-0.9	-2.7	-1.4
Tense / ‘highly strung’	0.8	1.3	3.5	0.7	1.3	1.1	0.7	1.6	1.2	1.3	-0.0	0.4	1.9	1.2
Hair/balding pattern: Pattern 4	0.8	1.9	3.6	-1.9	-1.2	0.9	0.9	1.6	0.8	-1.4	1.2	1.6	1.7	1.2
Gout (self-reported)	0.8	1.1	3.3	-0.9	-1.8	-1.5	-0.0	-1.6	-0.9	-0.8	-0.2	-0.3	-0.7	-1.0
Birth weight	0.8	1.7	4.9	-1.9	-1.9	-0.2	1.7	-0.5	0.8	-2.2	0.7	1.2	0.1	0.4
Body fat percentage	0.8	3.0	7.1	-0.6	-1.8	-2.4	-1.7	-2.7	-1.6	-2.1	-1.3	-0.9	-1.7	-1.1
Medication: Seretide 50 evohaler	0.8	0.9	2.3	0.2	0.9	1.1	0.6	1.5	1.2	0.5	1.1	0.8	1.0	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	2.6	1.6	0.1	0.0	-0.1	-1.4	-0.5	0.8	-1.1	-0.8	-1.4	-1.1
Had major operations	0.8	0.9	4.3	-1.1	-2.1	-0.2	0.1	0.7	0.2	-2.0	0.1	0.2	-0.2	-0.1
Family relationship satisfaction	0.8	0.9	5.5	-0.8	-0.7	0.6	0.4	0.5	1.0	-2.3	0.4	1.1	0.5	0.6
Long-standing illness, disability or infirmity	0.8	1.2	4.4	-1.8	-1.5	-0.0	-1.7	-0.3	-0.1	-2.1	-0.2	0.6	0.5	0.0
Commuting to job workplace: Public transport	0.8	0.9	4.4	-1.0	0.8	0.2	-1.0	0.3	-0.3	-0.7	0.1	1.0	2.1	1.2
Arm fat-free mass (left)	0.8	3.9	17.9	-2.1	-4.2	-0.9	1.7	-2.0	-0.4	-2.7	-0.4	0.3	-2.4	-0.6
Depression (Nagel 2018)	0.7	1.0	2.5	-1.5	-0.0	0.1	0.3	0.6	0.6	-1.1	1.2	1.4	1.6	1.2
Ulcerative Colitis	0.7	1.0	1.7	-0.1	-1.1	-1.2	-0.8	-0.5	-0.7	-1.0	-1.3	-1.3	-1.1	-1.1
Smoking Status	0.7	1.8	4.9	-1.9	-2.2	1.3	-0.0	1.7	1.1	-1.7	0.3	1.2	0.8	0.9
Chronotype (morning person)	0.7	1.5	3.3	-1.8	-0.9	0.9	1.1	1.8	1.0	-0.0	1.4	1.5	0.7	1.4
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.5	-1.0	-0.1	0.7	0.8	0.5	0.8	-0.5	0.9	1.3	1.6	1.5
Hearing difficulty/problems: Yes	0.7	1.1	3.9	-1.6	-1.0	-0.5	-1.0	0.5	-0.5	-2.0	1.1	1.0	-1.0	0.0
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	2.5	-0.2	0.5	1.5	0.5	1.6	1.3	-0.2	0.7	0.8	1.1	0.9
Medication: Co-codamol	0.7	0.8	2.4	-1.3	-1.5	-0.7	-0.7	-1.2	-0.3	-1.3	-0.2	-0.2	-0.6	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	5.2	0.5	1.1	-1.1	-1.7	-2.3	-0.6	0.2	-1.6	-1.6	-0.3	-1.2
Nervous feelings	0.7	1.3	4.0	0.4	1.2	1.3	0.7	1.1	2.0	1.1	0.4	0.6	1.7	1.0
Hair/balding pattern: Pattern 2	0.7	0.9	3.3	0.7	1.8	-0.1	0.4	1.8	0.1	1.2	0.4	0.3	1.1	0.4
Had menopause	0.7	0.8	2.8	1.7	0.9	-0.9	-0.2	-0.1	-1.1	0.1	-0.7	-1.1	-0.2	-1.3
Forced vital capacity (FVC)	0.7	2.8	11.3	-1.4	-2.9	0.8	3.4	-1.1	0.7	-1.5	0.7	0.7	-1.9	0.0
Weight	0.7	3.7	13.9	-1.6	-3.7	-1.2	0.8	-2.6	-0.5	-2.5	-0.5	0.1	-2.8	-0.8
Illnesses of mother	0.7	0.9	1.8	-0.0	0.8	1.2	1.1	0.9	0.7	0.8	1.3	0.9	0.7	1.4
Length of working week for main job	0.7	0.8	1.4	1.2	0.5	-0.9	-1.1	1.1	-1.1	-0.1	-1.0	-1.1	-0.5	-0.7
Ever highly irritable/argumentative for 2 days	0.7	0.8	2.2	-1.2	-0.3	1.5	0.8	0.4	1.1	-0.9	1.0	1.1	0.2	0.6
Arm fat-free mass (right)	0.7	3.6	16.2	-1.9	-4.0	-0.6	2.2	-1.9	-0.1	-2.4	-0.4	0.4	-2.2	-0.4
Whole body fat mass	0.7	3.1	7.7	-1.1	-2.8	-1.9	-0.5	-2.7	-1.1	-2.5	-1.0	-0.5	-2.1	-0.9
Arm fat mass (left)	0.7	2.9	7.3	-0.6	-2.6	-1.7	-0.4	-2.7	-1.2	-2.2	-1.0	-0.6	-2.4	-1.1
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.7	-1.3	0.1	0.0	0.4	-0.8	1.0	-0.7	1.2	1.2	0.5	1.3
Medication: Bendroflumethiazide	0.7	1.1	2.5	0.5	-0.1	-1.3	-1.6	-1.4	-0.9	0.4	-1.4	-1.1	-0.8	-0.9
Medication: Paracetamol	0.7	1.1	2.5	-0.5	-0.2	1.3	1.4	1.2	0.9	0.9	1.2	1.0	0.7	1.6
Supplements: Calcium	0.7	0.8	1.6	0.8	0.3	-1.2	-0.9	-0.5	-0.6	-0.3	-0.5	-1.3	-1.1	-1.1
Basal cell carcinoma (self-reported)	0.7	0.8	3.4	0.1	-0.2	-1.1	-0.8	0.8	-0.6	-0.1	-0.6	-0.7	-1.9	-1.2
Arm predicted mass (left)	0.7	3.8	17.5	-1.8	-4.2	-0.9	1.8	-1.9	-0.6	-2.5	-0.5	0.2	-2.4	-0.6
Breast Cancer	0.6	1.5	6.8	-0.8	-0.6	-2.6	-1.2	-0.3	-1.9	-0.6	-1.3	-0.5	0.9	-0.9
Schizophrenia (2014)	0.6	1.4	2.9	1.1	1.6	-0.6	-1.2	-1.6	-0.8	1.7	-1.3	-1.4	0.6	-0.5
Type 2 Diabetes (T2D) (2012)	0.6	0.7	4.6	-0.2	0.7	0.1	-0.6	2.2	0.2	0.5	-0.4	-0.2	1.4	0.3
Blood White Count	0.6	4.2	13.5	-1.3	-3.2	-2.5	-2.5	1.4	-0.9	-3.7	-1.5	-0.7	-0.7	-1.5
Hypothyroidism (self reported)	0.6	1.3	3.4	0.4	1.5	1.1	1.3	1.8	1.4	0.5	0.9	0.8	0.8	1.1
Average weekly fortified wine intake	0.6	0.7	2.4	0.7	1.6	0.5	0.6	0.9	1.2	0.1	0.0	0.4	1.1	0.9
Maternal smoking around birth	0.6	0.9	5.1	-0.7	-2.2	-0.2	1.1	-1.4	-0.2	-0.8	-0.3	-0.0	-0.2	-0.3
Relative age voice broke	0.6	0.8	2.8	1.0	1.7	1.0	-0.1	0.5	0.9	1.3	0.9	0.4	0.5	0.8
Tinnitus: Yes, but not now, but have in the past	0.6	0.6	2.0	-1.4	-0.5	0.4	0.6	0.4	0.6	-0.4	1.3	1.2	-0.2	0.7
Serious illness, injury or assault to yourself	0.6	0.8	1.7	0.3	1.1	0.9	-0.4	1.0	0.8	0.8	1.3	0.6	1.1	0.7
Hayfever, allergic rhinitis or eczema	0.6	1.3	3.6	0.9	1.6	1.7	0.9	0.6	0.3	1.9	1.4	0.5	0.4	0.9
Multivitamins +/- minerals	0.6	0.8	2.5	-1.6	-0.0	0.4	0.1	0.9	0.7	-0.7	1.3	1.4	0.1	0.9
Medication: Atenolol	0.6	0.7	1.6	0.6	-0.5	-1.1	-1.2	-0.3	-1.3	-0.6	-0.2	-0.8	-1.0	-0.9
Trunk fat-free mass	0.6	3.4	14.2	-1.7	-3.8	0.2	3.0	-1.1	0.4	-1.9	0.2	0.7	-2.5	-0.2
Trunk predicted mass	0.6	3.4	14.3	-1.7	-3.8	0.2	2.9	-1.1	0.4	-1.9	0.1	0.6	-2.5	-0.2
Exposure to tobacco smoke outside home	0.6	0.8	3.3	-0.2	-0.3	-0.8	-0.5	1.1	-1.3	-1.8	-0.7	-0.6	0.0	-0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	3.0	-1.5	-0.4	-0.4	0.0	-0.1	0.7	-1.7	0.6	1.1	0.6	0.9
Medication: Blood pressure	0.6	1.1	4.0	-0.5	-0.6	-1.2	-2.0	0.4	-1.6	-1.2	-1.3	-0.4	0.6	-0.3
Mean time to correctly identify matches	0.6	1.1	4.3	-1.6	-1.1	-1.1	-1.1	-1.1	-0.7	-2.1	-0.4	0.1	0.0	-0.3
Arm predicted mass (right)	0.6	3.3	15.6	-1.7	-4.0	-0.6	2.1	-1.8	-0.3	-2.1	-0.5	0.3	-2.2	-0.5
Leg fat-free mass (right)	0.6	3.4	11.8	-1.3	-2.7	1.6	3.4	-1.0	1.6	-0.8	1.5	1.6	-2.0	0.8
Eye problems/disorders: Cataract	0.6	0.7	1.9	1.0	0.6	-0.9	-0.3	-0.4	-0.7	0.4	-0.6	-1.4	-1.2	-1.0
Whole body water mass	0.6	3.2	12.2	-1.6	-3.5	0.7	3.0	-1.2	0.8	-1.6	0.6	1.0	-2.3	0.1
Leg predicted mass (right)	0.6	3.3	11.5	-1.4	-2.7	1.6	3.4	-1.0	1.6	-0.8	1.5	1.6	-2.0	0.8
Medication: Blood pressure	0.6	1.1	3.5	0.3	-0.3	-1.9	-1.5	-0.2	-1.5	0.1	-1.2	-0.8	-0.1	-1.4
Basal metabolic rate	0.6	3.0	12.0	-1.4	-3.5	0.3	2.6	-1.6	0.5	-1.6	0.4	0.7	-2.5	-0.1
Heart disease (siblings)	0.6	0.7	2.2	-0.7	-0.8	-1.1	-1.5	-0.6	-0.6	-1.3	-0.7	-0.3	-0.2	-0.5
Schizophrenia vs Biploar Disorder	0.5	0.6	1.1	0.1	0.8	0.9	0.7	0.1	1.0	0.5	0.6	1.1	0.9	1.0
Bipolar Disorder (2011)	0.5	0.5	1.9	-0.0	0.0	0.0	0.0	0.0	0.0	0.0	-1.1	-1.2	-0.7	-1.4
Primary Biliary Cirrhosis	0.5	0.8	2.4	1.2	1.5	0.3	-0.6	-1.1	-0.3	1.5	-0.3	-0.6	0.3	-0.1
Heel T-Score	0.5	3.9	14.8	1.4	3.9	-0.7	-3.0	-3.1	-0.9	2.1	-0.6	-0.7	0.7	0.2
Allergy or Eczema	0.5	1.3	2.3	0.1	1.1	1.5	0.7	1.4	1.0	1.5	1.4	1.0	0.8	1.1
Sensitivity / hurt feelings	0.5	0.8	2.2	-1.5	-0.9	0.1	0.4	0.6	0.9	-1.1	1.2	1.1	0.5	0.3
Diabetes (father)	0.5	0.6	2.6	-0.4	0.7	0.4	-0.2	0.9	-0.2	-0.4	0.7	1.0	1.6	1.0
Leg fat-free mass (left)	0.5	2.6	9.8	-0.7	-2.5	1.4	3.1	-1.0	1.2	-0.7	1.0	1.1	-2.3	0.4
Trunk fat percentage	0.5	1.8	6.7	-0.8	-1.6	-1.7	-1.0	-2.6	-0.8	-1.8	-0.6	-0.2	-1.4	-0.4
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.6	0.9	1.3	-0.7	-0.8	0.3	-0.4	0.8	-0.7	-1.1	0.2	-0.6
Sitting height	0.5	3.7	17.9	-0.5	-1.1	2.6	4.2	0.3	2.5	0.7	1.7	1.2	-1.5	1.0
Leg predicted mass (left)	0.5	2.6	9.5	-0.7	-2.5	1.3	3.1	-1.0	1.2	-0.7	0.9	1.0	-2.3	0.4
Trunk fat mass	0.5	2.3	6.6	-1.3	-2.6	-1.4	-0.1	-2.5	-0.7	-2.3	-0.5	0.0	-1.8	-0.4
Waist circumference	0.5	1.8	6.8	-2.2	-2.6	-0.9	-0.4	0.0	-0.3	-2.6	-0.2	0.8	-0.1	0.4
Diabetes (self-reported)	0.5	0.8	2.9	0.3	0.3	-0.0	-1.3	1.7	-0.5	-0.4	-1.2	-0.8	0.7	-0.8
Arm fat percentage (right)	0.5	1.9	4.9	0.3	-1.1	-1.7	-1.4	-2.2	-1.2	-1.1	-1.1	-0.9	-1.9	-1.1
Time employed in main current job	0.5	0.5	1.4	-0.4	-0.7	-0.8	-1.2	-0.9	-1.1	-0.6	-0.8	-0.3	0.2	-0.1
Falls in the last year	0.5	0.7	2.3	1.0	1.5	0.2	-1.3	0.8	-0.5	0.4	0.5	-0.0	0.7	0.5
Medication: Lansoprazole	0.5	0.5	1.6	-0.9	0.1	-0.2	0.2	0.5	0.2	-1.3	-0.0	0.4	1.2	1.1
Prospective memory result	0.5	0.6	1.8	-0.4	-0.6	-1.0	-1.3	-0.2	-0.9	-0.8	-1.1	-0.5	0.2	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	10.6	-0.3	-0.9	1.7	3.3	-0.2	1.1	-0.1	1.0	1.0	-0.6	1.0
Eye problems/disorders: None of the above	0.5	0.6	1.7	-0.8	-0.7	0.5	0.6	0.0	0.6	-0.3	1.0	1.3	1.0	0.7
Comparative height size at age 10	0.5	2.8	7.5	-1.4	-2.2	1.3	2.7	-2.2	1.4	-0.3	0.9	0.8	-2.3	0.6
Overall health rating	0.5	1.0	2.9	-1.5	-0.5	0.3	-0.1	0.8	1.0	-1.0	0.7	1.3	1.7	1.0
Chest pain or discomfort	0.5	0.8	1.9	0.9	0.3	-1.0	-0.4	0.2	-0.8	-0.7	-1.2	-1.1	-0.8	-1.4
Smoking status: Previous	0.5	0.7	3.8	-0.7	-1.5	0.6	-0.3	0.3	0.0	-1.9	0.1	0.5	-0.6	0.3
Whole body fat-free mass	0.5	3.1	12.0	-1.5	-3.5	0.6	3.0	-1.3	0.7	-1.6	0.5	0.8	-2.4	0.0
Arm fat percentage (left)	0.5	2.0	5.8	0.2	-1.3	-1.7	-1.2	-2.4	-1.2	-1.2	-1.1	-0.9	-2.0	-1.1
Diabetes diagnosed by doctor	0.5	0.8	3.7	-0.0	0.0	-0.0	-1.2	1.9	-0.1	-0.0	-1.1	-0.6	1.2	-0.5
Osteoarthritis (self-reported)	0.5	0.6	2.0	1.0	0.5	0.1	-1.4	-0.6	-0.4	-0.2	-0.4	-0.8	-1.0	-0.9
Eye problems/disorders: Glaucoma	0.5	0.6	1.4	-0.6	0.5	1.1	0.7	-1.1	1.2	0.2	0.5	0.8	0.2	0.7
Average weekly beer plus cider intake	0.5	0.7	2.4	1.4	0.4	0.5	1.0	0.5	-0.5	1.5	-0.3	-0.6	-0.8	-0.3
Unable to work because of sickness or disability	0.5	0.7	1.6	-0.1	0.8	1.2	-0.6	0.3	0.8	0.5	0.5	1.1	0.9	1.3
Impedance of whole body	0.5	2.5	9.3	0.8	3.0	1.4	0.2	0.9	1.6	1.9	1.6	0.6	1.6	1.8
Reaction Time	0.4	0.7	2.4	-1.4	-0.9	0.1	-0.4	0.6	0.3	-1.6	0.9	0.8	0.5	0.6
Height	0.4	7.3	16.2	-2.5	-3.3	2.0	4.0	-2.4	2.0	-2.1	2.8	2.2	-3.5	2.0
Cardiovascular Disease	0.4	1.3	5.3	-0.7	-0.4	-0.6	1.1	2.3	0.4	0.6	-0.3	0.9	2.2	0.6
Number of treatments/medications taken	0.4	0.7	2.2	-0.3	-0.9	-1.2	-1.2	-0.8	-1.5	-0.4	-0.9	-0.4	-0.3	-0.6
Medication for hormone replacement therapy	0.4	0.4	1.5	-0.2	-1.0	0.5	0.3	1.2	0.5	-1.1	-0.3	0.3	-0.2	-0.5
Diabetes (mother)	0.4	0.5	1.7	-0.7	-0.2	-0.0	-0.2	1.3	0.6	-0.9	1.0	1.0	0.2	0.3
High blood pressure	0.4	1.2	2.5	-0.4	-0.6	-1.4	-1.3	1.5	-1.6	-0.4	-1.5	-0.2	0.9	-0.8
Medication: Levothyroxine sodium	0.4	0.7	1.6	0.2	0.7	0.4	1.3	1.2	1.1	-0.2	1.0	0.9	0.3	0.6
Hearing difficulty/problems with background noise	0.4	0.7	2.1	-0.3	-0.8	-0.6	-1.4	-0.1	-1.2	-0.6	0.1	0.1	-1.5	-0.8
Had other major operations	0.4	0.5	1.3	0.1	-0.7	0.0	-0.5	-0.9	-1.1	-0.8	-0.9	-0.5	-0.7	-0.5
Heart attack	0.4	0.5	1.9	-0.9	-0.0	0.6	-0.3	-0.7	0.3	-0.2	1.4	1.1	0.2	0.7
Pain all over the body in last month	0.4	0.5	3.1	-0.4	0.4	0.0	-0.3	0.4	0.3	-0.3	0.2	0.5	1.8	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	2.0	0.4	0.6	0.5	-0.2	0.8	-0.3	0.7	0.2	-0.1	1.4	0.9
Lung cancer (father)	0.4	0.5	1.7	-1.2	-1.1	0.3	1.3	0.3	0.1	0.2	0.3	0.7	0.2	0.4
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.1	0.8	0.4	0.6	0.9	-0.8	0.8	0.9	0.3	-0.6	-1.5	-0.6
Forced vital capacity (FVC), Best measure	0.4	1.6	10.7	-0.2	-1.5	0.7	3.3	-1.2	0.5	-0.4	0.2	0.3	-1.3	0.1
Neck or shoulder pain in last month	0.4	0.5	2.4	-0.7	-0.7	-0.9	-1.1	-0.7	0.0	-1.5	-0.1	0.1	-0.2	-0.1
Number of full sisters	0.4	0.5	2.2	-0.6	0.0	0.8	-0.2	1.5	0.5	0.1	1.0	0.9	0.7	0.6
Commuting to job workplace: Car/motor vehicle	0.4	0.5	3.0	-0.3	0.2	0.2	1.7	-0.5	0.9	0.3	0.8	0.5	0.1	0.4
Mood swings	0.4	0.8	2.8	-0.4	0.7	0.8	0.5	1.7	0.9	0.1	1.2	0.7	0.9	1.1
Illnesses of father: None of the above (group 1)	0.4	0.5	2.2	0.2	-0.2	0.7	1.5	-0.8	0.1	-0.1	0.6	-0.2	-1.4	-0.4
Guilty feelings	0.4	0.7	1.6	-1.3	-0.3	0.7	0.0	0.5	0.4	-0.7	0.8	1.2	1.1	0.9
Cholesterol lowering medication	0.4	0.5	1.6	-1.1	-0.1	-0.4	0.1	1.2	0.5	-0.6	0.3	0.9	1.2	0.3
Intelligence (Savage-Jansen 2018)	0.3	0.8	2.0	-1.0	-0.6	1.2	0.0	-0.6	1.0	-1.0	1.1	1.4	-0.2	0.7
Verbal and Numeric Reasoning (VNR)	0.3	0.7	1.7	0.7	1.1	1.3	0.3	0.2	0.6	1.3	1.0	0.7	-0.2	0.6
Age at First Birth	0.3	0.5	1.6	-1.3	-0.0	0.2	-0.0	-0.3	0.6	-1.1	0.8	1.0	0.3	0.5
Coronary Artery Disease (CAD)	0.3	0.4	2.9	0.4	-0.5	0.0	-0.1	1.7	0.0	-0.4	-0.8	-0.4	0.0	-0.1
Blood Platelet Count	0.3	3.0	6.6	-0.9	-2.4	-2.6	-1.5	-0.4	-2.2	-2.3	-2.1	-1.3	-0.2	-1.2
Qualifications: CSEs or equivalent	0.3	0.4	2.2	-0.6	-1.5	-0.5	0.8	0.0	-0.2	-0.1	0.6	0.2	-0.8	-0.1
Stomach or abdominal pain in last month	0.3	0.4	2.4	-0.2	0.1	-0.1	-0.7	1.5	-0.1	-0.3	-0.1	0.7	0.8	0.7
Chronic bronchitis/emphysema (father)	0.3	0.3	1.3	-1.1	-0.9	0.4	-0.2	-0.3	-0.0	-0.4	0.2	0.2	1.0	0.5
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.4	1.9	0.5	0.8	0.7	0.4	1.4	0.1	-0.2	0.4	0.7	0.2	0.7
Pulse rate	0.3	0.5	2.3	-0.3	0.3	1.2	0.3	1.5	0.7	0.1	0.4	0.6	0.8	0.4
Birth weight of first child	0.3	0.5	2.9	-1.0	-0.5	-0.4	0.6	-0.2	-0.2	-1.7	0.4	0.3	-0.5	-0.0
High blood pressure (siblings)	0.3	0.5	2.8	-0.7	-0.3	-0.3	-0.6	0.6	-0.3	-1.7	-0.5	0.2	0.8	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.9	1.0	1.4	-0.3	0.1	-0.1	-0.6	0.8	-0.2	-0.1	0.5	0.1
Emphysema/chronic bronchitis	0.3	0.4	2.0	0.4	0.3	0.4	0.8	-0.7	0.3	1.4	0.1	-0.5	-0.1	0.1
Alcohol intake frequency.	0.3	0.8	2.6	-0.5	-0.9	-1.6	-1.1	-0.2	-0.8	-0.8	-1.2	-0.6	0.2	-1.0
Medication: Aspirin	0.3	0.4	1.3	-0.5	-0.6	-0.5	-0.8	-0.5	0.0	-1.1	-0.5	-0.0	0.9	-0.2
Hypertension (Self-reported)	0.3	0.9	2.8	0.1	-0.1	-1.1	-1.0	1.7	-1.2	0.3	-1.5	-0.2	1.0	-0.7
Osteoporosis (self-reported)	0.3	0.3	1.0	-0.0	-0.7	-0.6	-0.5	-1.0	-0.5	-0.5	-0.1	-0.4	-0.7	-0.7
Medication: Aspirin	0.3	0.4	2.0	-0.7	-0.8	-0.4	-0.7	-0.5	-0.2	-1.4	-0.3	0.3	0.8	-0.1
Smoking status: Current	0.3	0.5	1.7	-1.0	-0.7	0.3	-0.1	0.9	0.7	0.7	-0.3	0.5	1.3	0.6
Financial situation satisfaction	0.3	0.4	1.5	-0.5	-0.9	0.1	0.0	-1.1	-0.1	-1.2	-0.3	0.1	-0.7	-0.4
Medication: Lisinopril	0.3	0.4	1.2	0.1	0.6	-0.5	-0.9	0.0	-0.8	-0.3	-0.1	0.9	1.1	0.7
Medication: Atorvastatin	0.3	0.4	1.7	-0.5	0.2	0.1	-0.1	0.3	-0.4	0.4	-0.0	0.9	1.3	0.9
Vascular/heart problems diagnosed by doctor	0.3	0.9	2.0	0.3	0.4	1.3	1.1	-1.3	1.4	0.4	1.2	0.1	-1.0	0.7
Heart attack/myocardial infarction (self-reported)	0.3	0.4	1.2	-0.8	0.0	0.3	-0.7	-1.0	0.0	-0.2	1.1	0.8	-0.1	0.3
Alzheimer’s Disease (in mother)	0.2	0.2	1.2	0.7	0.3	-0.2	-0.1	-0.0	-0.0	-0.1	-0.5	-0.7	-0.5	-1.1
Irritable Bowel Disease (IBD)	0.2	0.4	1.2	-0.8	-0.1	0.1	1.1	0.3	0.7	-0.2	-0.2	0.2	1.0	0.8
HDL Cholesterol	0.2	0.4	1.3	-1.0	0.0	-0.3	-0.5	-1.1	0.6	-0.5	-0.0	0.3	0.7	0.5
Systolic Blood Pressure	0.2	0.8	2.2	-0.8	-0.9	-1.5	-1.0	-0.2	-1.1	-1.5	-0.7	-0.2	-0.1	-0.4
Respiratory disease	0.2	0.5	2.3	0.2	-0.4	0.0	1.5	-0.0	0.3	1.5	0.1	0.2	0.3	-0.2
Impedance of leg (right)	0.2	1.1	2.6	0.8	1.6	-1.3	-1.6	1.1	-0.9	0.1	-0.7	-1.0	1.0	-0.2
Townsend deprivation index at recruitment	0.2	0.3	0.5	-0.7	-0.6	0.7	-0.7	-0.1	0.4	-0.6	-0.2	0.4	0.2	0.4
Current tobacco smoking	0.2	0.4	0.9	-0.4	-0.5	0.3	-0.2	0.9	0.5	0.9	-0.7	-0.1	0.9	0.1
Taking other prescription medications	0.2	0.2	0.7	-0.6	-0.5	-0.4	-0.8	0.2	-0.5	-0.5	0.6	0.5	0.2	-0.2
High blood pressure (mother)	0.2	0.2	0.7	-0.5	-0.9	-0.1	-0.2	-0.2	0.7	-0.4	-0.8	-0.5	-0.1	-0.2
Impedance of leg (left)	0.2	0.8	2.4	-0.6	0.9	-1.4	-1.5	0.6	-0.6	-0.6	-0.4	-0.3	1.5	0.3
Allergy	0.2	0.4	1.6	-0.9	-0.5	-0.7	-0.7	-0.1	0.3	-1.3	-0.3	0.2	0.3	0.2
Mouth/teeth dental problems: Dentures	0.2	0.3	1.0	-0.3	0.1	0.2	-1.0	-0.4	0.5	-0.9	0.3	0.6	0.5	0.0
Asthma	0.2	0.3	1.8	0.8	0.1	0.1	0.7	-0.2	-0.1	1.3	-0.1	-0.4	-0.1	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	1.9	-0.4	0.6	-1.0	-1.4	-0.1	0.2	-0.3	0.2	0.1	0.6	0.3
Blood clot in the leg (DVT)	0.2	0.2	0.8	-0.1	-0.0	0.4	0.2	0.6	0.3	-0.6	0.6	0.9	-0.0	-0.2
Age at first live birth	0.2	0.3	0.6	0.0	-0.7	-0.1	0.3	-0.6	-0.6	-0.3	-0.7	-0.6	-0.7	-0.8
Qualifications: College or University degree	0.2	0.8	4.5	1.4	2.1	0.0	0.2	0.6	0.2	1.2	0.1	-0.1	0.4	0.0
Heart disease (mother)	0.2	0.3	1.2	0.3	0.1	-0.6	-0.9	-0.1	-0.5	1.1	-0.7	-0.3	0.2	-0.1
Pulse rate, automated reading	0.2	0.6	4.8	0.2	0.4	0.8	0.0	2.2	-0.1	0.5	-0.1	0.2	1.0	0.1
Age at last live birth	0.2	0.3	0.8	0.4	-0.3	0.0	-0.8	0.6	-0.6	0.3	-0.6	-0.7	-0.9	-0.7
Leg pain on walking	0.2	0.3	1.4	-0.6	-0.5	-0.3	-1.2	-1.0	0.1	-0.4	0.2	0.3	0.1	0.1
Knee pain experienced in last month	0.2	0.4	1.0	0.2	-0.0	-0.2	-1.0	-0.9	-0.6	0.3	-0.4	-0.7	0.9	0.3
Loneliness, isolation	0.2	0.3	1.3	0.5	0.4	1.1	-0.2	-0.3	1.0	-0.6	0.6	0.3	-0.0	0.1
Qualifications: nursing, teaching	0.2	0.4	1.0	0.0	0.5	0.3	0.7	-0.6	0.5	0.6	0.8	0.7	0.6	1.0
Medication for cholesterol	0.2	0.4	1.5	0.4	0.3	0.6	0.5	-1.2	0.0	0.4	0.7	-0.2	-0.8	0.4
Ever had prostate specific antigen (PSA) test	0.2	0.2	1.9	-0.2	0.5	0.1	0.2	-1.4	-0.5	-0.2	0.0	-0.3	-0.1	-0.3
Fractured/broken bones in last 5 years	0.2	0.3	1.1	0.7	-0.1	0.0	-0.6	-0.1	0.8	-1.1	0.2	0.3	-0.8	-0.4
Pain experienced in last month	0.2	0.3	2.3	-0.0	-0.2	-0.1	0.2	-0.4	0.4	0.0	0.5	0.0	-1.5	-0.7
Ulcerative Colitis (UC)	0.1	0.2	1.0	-0.6	-0.6	-1.0	-0.2	-0.4	0.2	-0.4	-0.6	-0.1	0.1	-0.1
Tanning	0.1	1.0	4.2	-1.9	-2.1	-0.1	-0.5	0.1	-0.1	-1.6	-0.4	-0.0	0.3	0.0
Ever used hormone-replacement therapy (HRT)	0.1	0.2	1.0	-0.3	0.3	0.0	0.1	0.5	0.2	-0.2	-0.3	0.3	1.0	0.2
Age when periods started (menarche)	0.1	0.3	1.1	0.1	1.1	0.7	0.3	0.4	0.4	0.6	0.5	0.6	0.6	0.4
Medication: Paracetamol	0.1	0.2	0.6	-0.2	-0.7	0.5	0.5	0.6	0.2	0.3	0.4	-0.0	-0.1	0.8
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.4	0.3	0.3	0.1	0.3	0.3	0.4	-0.6	0.2	0.2	-0.5	-0.1
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.7	0.1	0.0	0.6	0.4	0.1	0.8	0.6	0.6	0.3	0.2	0.0
Number of full brothers	0.1	0.1	0.2	0.4	0.1	0.3	-0.1	0.1	0.5	-0.3	0.4	0.1	-0.5	-0.4
Wheeze or whistling in the chest in last year	0.1	0.1	0.5	0.4	-0.0	-0.0	-0.1	-0.2	-0.3	0.0	-0.6	-0.7	-0.2	-0.2
Medication for pain relief, constipation, heartburn	0.1	0.2	0.6	0.0	0.2	0.3	0.7	-0.1	0.3	0.2	0.5	0.4	-0.8	-0.1
Medication: Omeprazole	0.1	0.1	0.2	-0.3	-0.2	-0.3	-0.5	-0.1	-0.5	-0.4	0.1	0.3	-0.2	-0.4
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.8	0.2	-0.1	0.3	-0.0	-0.0	0.9	0.7	0.1	-0.2	-0.1	0.0
Back pain experienced in last month	0.1	0.1	0.5	-0.7	-0.3	0.3	-0.3	0.2	-0.1	-0.5	-0.2	0.4	0.5	0.1
Asthma (self-reported)	0.1	0.2	1.3	0.7	0.0	-0.1	0.4	0.2	-0.3	1.2	-0.3	-0.4	0.0	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.1	0.7	0.1	-0.2	0.1	0.8	-0.8	-0.0	-0.2	0.0	-0.3	0.2	0.3
Average weekly champagne plus white wine intake	0.1	0.1	0.4	-0.3	0.5	0.1	-0.0	0.6	-0.1	0.5	0.1	0.1	0.5	-0.1
Illnesses of father: High blood pressure	0.1	0.2	0.6	0.1	-0.6	-0.3	0.0	0.5	0.3	0.2	-0.6	-0.6	0.7	0.0
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.7	-0.0	-0.2	-0.4	-0.3	0.6	-0.3	-0.8	0.1	0.4	-0.3	-0.5
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.4	0.0	-0.1	0.3	0.1	0.2	0.2	-0.5	0.4	0.6	-0.3	-0.4
Blood Red Count	0.0	0.5	2.5	0.3	0.5	-1.6	-0.0	-1.1	-0.6	-0.1	0.5	0.0	-0.5	-0.2
Hair Pigment	0.0	0.3	0.8	-0.5	-0.1	0.5	0.4	-0.6	-0.2	-0.9	0.4	-0.7	-0.9	-0.4
Number of self-reported non-cancer illnesses	0.0	0.0	0.1	-0.1	-0.2	0.0	-0.3	0.1	-0.1	0.2	-0.1	0.4	0.2	-0.1

Hub : Genes

RPL32P3

Models

Trait associations