Hub : Genes

RSBN1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.047 0.021 0.0085 0.018 0.004 0.021 0.004 0.013 0.00280 0.089 1.3e-03 0.087 0.00950
2 GTEx Testis 0.094 0.044 0.0029 0.086 NA 0.089 NA 0.087 0.00012 NA 8.9e-05 NA 0.00011

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 2.0 3.1 5.8 0.6 -2.4
Bipolar Disorder or Schizophrenia 1.9 4.5 8.0 1.0 -2.8
Depressed Affect (Nagel 2018) 0.2 0.4 0.6 -0.6 -0.8
Depression (Nagel 2018) 1.3 1.9 2.0 -1.4 -1.4
Intelligence (Savage-Jansen 2018) 1.5 4.5 4.8 -2.1 2.2
Neuroticism (Nagel 2018) 0.2 0.4 0.8 -0.9 0.3
Schizophrenia (2018) 0.8 1.7 2.9 0.8 -1.7
Schizophrenia vs Biploar Disorder 0.1 0.1 0.2 -0.4 0.1
Worry (Nagel 2018) 0.0 0.1 0.1 -0.3 -0.2
Alzheimer’s Disease (in mother) 0.1 0.1 0.1 -0.3 -0.3
Alzheimer’s Disease (in father) 0.8 0.8 1.7 -0.1 -1.3
Alzheimer’s Disease (including proxy) 0.1 0.1 0.1 0.3 -0.3
Crohns Disease (2017) 2.4 5.3 10.6 0.0 3.3
Irritable Bowel Disease (IBD) 0.7 1.7 3.2 0.4 1.8
Ulcerative Colitis (UC) 0.1 0.1 0.2 0.5 -0.1
Major Depression (MDD) 1.2 1.5 2.8 -0.4 -1.7
Reaction Time 2.8 5.3 10.5 0.1 3.2
Verbal and Numeric Reasoning (VNR) 0.4 0.8 1.4 -0.5 1.2
Breast Cancer 1.4 3.4 6.3 0.7 2.5
Ovarian Cancer 3.9 5.1 9.7 -3.1 0.7
Prostate Cancer 1.1 1.6 2.2 -1.0 1.5
Age at First Birth 0.6 0.9 1.4 1.2 -0.7
Bipolar Disorder (2011) 3.4 3.3 6.1 -0.7 -2.5
Body Mass Index (BMI) (2010) 0.2 0.3 0.4 0.4 -0.6
Coronary Artery Disease (CAD) 0.2 0.2 0.4 -0.2 -0.6
Crohns Disease (2012) 1.6 2.6 5.1 -0.2 2.2
Mean Putamen Volume 0.3 0.3 0.6 0.1 -0.8
Fasting Glucose 1.0 1.2 1.3 1.1 1.1
HbA1C 0.5 0.5 1.0 -0.3 -1.0
HDL Cholesterol 0.3 0.5 1.0 0.2 -1.0
LDL Cholesterol 1.9 3.1 6.2 -2.5 -0.1
Lupus 4.1 6.2 9.0 1.8 -3.0
Neuroticism (2016) 0.2 0.3 0.6 -0.1 0.8
Primary Biliary Cirrhosis 0.1 0.1 0.2 -0.1 0.4
Rheumatoid Arthritis 48.3 66.4 114.5 4.3 -10.7
Schizophrenia (2014) 0.3 0.7 0.8 0.9 -0.8
Triglycerides 0.3 0.5 0.9 -0.9 0.2
Type 2 Diabetes (T2D) (2012) 0.0 0.0 0.1 0.2 0.2
Ulcerative Colitis 0.1 0.2 0.4 -0.6 0.1
Blood Eosinophil Count 0.0 0.0 0.0 -0.0 0.2
Blood Platelet Count 0.4 4.8 9.4 -3.1 0.5
Blood Red Count 0.1 1.2 2.0 1.4 0.7
Blood White Count 1.4 10.5 15.8 -2.3 4.0
Heel T-Score 0.4 3.0 3.5 1.9 -1.6
BMI 1.5 9.0 17.5 0.7 -4.2
Height 0.1 1.7 3.2 -0.4 1.8
Waist Hip Ratio (WHR) 0.2 1.0 2.0 1.4 0.2
Systolic Blood Pressure 0.5 2.3 3.7 0.9 1.9
Smoking Status 0.3 0.6 1.2 0.1 1.1
Allergy or Eczema 2.3 6.1 11.4 -0.8 3.4
Cardiovascular Disease 0.7 2.2 4.3 -0.2 -2.1
Hypothyroidism (self reported) 56.6 130.0 225.0 5.9 -15.0
Respiratory disease 0.0 0.1 0.1 -0.2 -0.4
Type 2 Diabetes (T2D) (2018) 1.0 1.9 3.1 -0.8 -1.8
Lung FEV1/FVC ratio 0.3 1.6 2.8 0.7 -1.7
Lung FVC 0.1 0.4 0.8 -0.0 -0.9
Neuroticism 0.9 2.1 2.9 -1.7 1.1
Chronotype (morning person) 0.5 1.0 2.1 -0.2 -1.4
Hair Pigment 0.1 2.4 3.6 -1.1 -1.9
Tanning 0.1 1.3 1.7 1.3 0.9
Hand grip strength (left) 0.4 1.0 1.9 0.3 1.4
Number of treatments/medications taken 7.5 13.5 22.8 -2.1 -4.8
Average weekly spirits intake 2.3 2.8 5.4 -0.5 2.3
Sensitivity / hurt feelings 0.8 1.4 1.6 -1.3 1.1
Frequency of depressed mood in last 2 weeks 1.0 1.4 2.4 -1.5 -0.6
Hearing difficulty/problems: Yes 0.6 0.8 1.4 0.6 -1.2
Relative age of first facial hair 1.1 2.2 3.0 -1.2 1.7
Other serious medical condition/disability diagnosed by doctor 9.0 11.7 12.5 3.5 -3.3
Ever used hormone-replacement therapy (HRT) 2.0 2.5 4.8 -0.4 2.2
Ever had hysterectomy (womb removed) 0.7 0.8 1.6 -0.3 1.2
Systolic blood pressure, automated reading 0.1 0.3 0.6 -0.1 0.8
Eye problems/disorders: Diabetes related eye disease 1.6 1.8 3.3 -0.5 -1.8
Angina 2.1 2.8 4.2 1.2 -2.1
Medication for hormone replacement therapy 0.2 0.2 0.3 -0.6 -0.2
Vitamin and mineral supplements 0.1 0.1 0.1 0.1 0.4
Supplements: Zinc 0.6 0.6 1.1 -1.0 0.4
Medication: Co-codamol 1.1 1.3 1.4 1.2 -1.1
Medication: Metformin 2.5 3.5 7.0 -0.3 -2.6
Diabetes (father) 3.2 4.0 4.5 -2.1 -1.9
Diabetes (mother) 1.4 1.8 2.8 -0.9 1.7
Severe depression (siblings) 1.5 1.7 2.5 1.6 -0.9
Pack years adult smoking proportion 0.9 1.3 1.5 -1.2 -1.1
Impedance of leg (right) 0.6 2.7 3.6 -1.4 1.9
Leg fat-free mass (left) 0.5 2.9 4.5 1.1 -2.1
Trunk fat percentage 0.9 3.8 6.3 -1.1 -2.5
Hand grip strength (right) 0.0 0.0 0.0 0.0 0.2
Townsend deprivation index at recruitment 2.0 2.8 4.5 -2.1 1.0
Current tobacco smoking 0.2 0.3 0.4 -0.5 0.6
Average weekly fortified wine intake 0.5 0.6 0.9 0.6 0.9
Maternal smoking around birth 0.6 0.9 1.7 -0.0 1.3
Fed-up feelings 0.0 0.0 0.1 -0.2 0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 0.8 -0.9 -0.2
Relative age voice broke 0.6 0.8 1.5 -0.4 1.2
Taking other prescription medications 10.6 16.3 31.5 1.1 -5.6
Age when periods started (menarche) 1.6 3.8 7.6 -0.2 2.8
Bilateral oophorectomy (both ovaries removed) 1.5 1.7 2.6 -0.9 1.6
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.1 0.3 -0.5 0.1
Tinnitus: Yes, but not now, but have in the past 1.3 1.4 2.4 0.7 -1.6
Qualifications: CSEs or equivalent 0.1 0.2 0.4 0.0 -0.6
Serious illness, injury or assault to yourself 4.5 5.5 6.7 -2.1 -2.6
High blood pressure 0.3 0.8 1.4 -1.2 -0.5
Hayfever, allergic rhinitis or eczema 2.0 4.3 8.4 0.4 2.9
Multivitamins +/- minerals 0.3 0.3 0.7 -0.0 -0.8
Stomach or abdominal pain in last month 0.4 0.5 0.6 0.7 -0.8
Supplements: Glucosamine 6.3 8.2 13.0 -3.6 1.9
Diverticular disease/diverticulitis (self-reported) 1.6 2.0 3.8 -2.0 -0.3
Medication: Atenolol 1.8 2.3 4.3 -0.5 -2.1
Medication: Levothyroxine sodium 34.5 58.4 97.2 4.4 -9.9
Sitting height 0.3 2.1 4.0 2.0 -0.5
Chronic bronchitis/emphysema (father) 2.9 3.4 6.1 -2.5 0.9
High blood pressure (mother) 1.1 1.6 3.1 0.2 -1.8
Body mass index (BMI) 1.1 4.6 9.1 0.2 -3.0
Impedance of leg (left) 0.7 3.4 4.6 -1.5 2.1
Leg predicted mass (left) 0.6 3.1 4.9 1.1 -2.2
Trunk fat mass 0.9 3.7 6.9 -0.7 -2.6
Waist circumference 1.0 3.8 7.1 0.7 -2.7
Number of incorrect matches in round 1.8 2.9 5.0 0.9 -2.2
Past tobacco smoking 0.9 1.6 3.3 0.1 -1.8
Alcohol usually taken with meals 1.7 2.8 5.5 -0.1 -2.4
Nervous feelings 0.2 0.3 0.5 -0.5 -0.7
Frequency of tenseness / restlessness in last 2 weeks 2.1 3.3 4.3 -1.5 -2.1
Hearing difficulty/problems with background noise 0.1 0.2 0.3 -0.4 0.6
Hair/balding pattern: Pattern 2 0.1 0.1 0.1 -0.4 0.3
Had menopause 0.1 0.2 0.2 0.4 -0.4
Had other major operations 0.3 0.4 0.7 -0.8 0.3
Forced vital capacity (FVC) 0.0 0.2 0.4 0.1 0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.0 0.0 0.1 0.2 -0.2
Ever unenthusiastic/disinterested for a whole week 1.5 1.9 2.5 1.1 -1.6
Qualifications: None of the above 0.8 1.7 2.7 -1.6 0.9
Financial difficulties in last 2 years 0.5 0.7 1.4 1.2 -0.2
Mouth/teeth dental problems 0.6 0.9 1.9 -0.0 1.4
Heart attack 2.0 2.5 4.4 -0.8 -2.1
Allergy 1.1 2.5 4.6 0.6 -2.2
Pain all over the body in last month 1.9 2.0 3.9 -2.0 -0.4
Diabetes (self-reported) 3.9 5.9 11.8 -0.2 -3.4
Hayfever/allergic rhinitis (self-reported) 2.5 3.3 4.6 2.2 1.4
Medication: Ramipril 1.3 1.6 3.3 -1.8 -0.1
Medication: Simvastatin 1.3 1.9 3.8 -1.9 -0.3
Fluid intelligence score 0.3 0.7 1.2 -0.4 1.1
Illnesses of siblings 2.3 3.2 4.8 2.2 -1.3
Neuroticism score 0.2 0.4 0.7 -0.9 -0.0
Weight 0.7 3.4 6.6 0.4 -2.6
Impedance of arm (right) 0.5 2.2 3.6 -0.9 1.9
Arm fat percentage (right) 0.9 3.4 6.7 -0.2 -2.6
Trunk fat-free mass 0.3 1.7 2.3 1.5 -1.0
Hip circumference 0.9 3.7 7.4 -0.2 -2.7
Time employed in main current job 0.4 0.4 0.8 -0.9 0.4
Alcohol intake versus 10 years previously 0.6 1.0 1.9 1.4 0.2
Father’s age at death 0.9 1.3 2.4 -0.4 1.5
Worrier / anxious feelings 0.1 0.2 0.4 0.6 0.1
Frequency of tiredness / lethargy in last 2 weeks 1.6 2.6 2.7 -1.6 -1.6
Falls in the last year 0.7 1.0 1.7 -1.3 -0.5
Hair/balding pattern: Pattern 3 1.6 2.4 4.2 0.8 2.1
Number of live births 0.9 1.2 2.5 -0.1 1.6
Forced expiratory volume in 1-second (FEV1) 0.0 0.0 0.0 -0.1 -0.1
Pulse rate 1.1 1.9 3.4 1.8 -0.6
Happiness 0.2 0.2 0.4 -0.0 -0.6
Noisy workplace 0.1 0.2 0.3 0.0 -0.6
Qualifications: A levels/AS levels or equivalent 0.1 0.2 0.3 0.6 -0.2
Serious illness, injury or assault of a close relative in last 2 years 1.4 1.6 3.1 -1.8 -0.2
Mouth/teeth dental problems: Dentures 0.1 0.1 0.2 0.4 0.1
Asthma 0.3 0.6 1.1 1.0 0.3
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.7 1.0 -1.0 -0.7
Medication: Cholesterol lowering 3.8 6.0 9.9 -1.4 -3.1
Depression (self-reported) 1.6 1.9 3.8 -0.2 -2.0
Medication: Lansoprazole 0.1 0.1 0.2 0.4 -0.2
Prospective memory result 0.6 0.8 1.3 0.5 -1.1
Lung cancer (father) 0.6 0.7 1.0 -0.6 1.0
Illnesses of mother 2.2 2.8 3.0 -1.7 1.6
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.2 0.2 0.5 -0.5
Pulse wave Arterial Stiffness index 2.4 2.8 5.5 -0.1 2.3
Impedance of arm (left) 0.5 2.3 2.9 -1.3 1.7
Arm fat mass (right) 0.8 3.1 6.2 0.2 -2.5
Trunk predicted mass 0.3 1.6 2.3 1.5 -1.0
Standing height 0.1 0.6 0.8 0.6 0.9
Length of working week for main job 2.1 2.3 3.9 -0.8 2.0
Exposure to tobacco smoke at home 0.5 0.5 0.8 -0.9 0.5
Breastfed as a baby 0.5 0.6 0.8 -0.6 0.9
Tense / ‘highly strung’ 1.8 3.0 5.6 -2.4 -0.6
Seen doctor (GP) for nerves, anxiety, tension or depression 0.0 0.1 0.1 -0.4 0.0
Hair/balding pattern: Pattern 4 0.3 0.8 1.6 -0.1 -1.3
Birth weight of first child 1.3 2.3 4.6 0.3 2.1
Peak expiratory flow (PEF) 0.1 0.2 0.2 0.4 0.4
Pulse wave reflection index 1.6 2.0 3.6 -0.6 1.9
Ever highly irritable/argumentative for 2 days 1.5 1.8 3.2 -1.8 0.7
Loud music exposure frequency 0.1 0.1 0.2 0.1 -0.4
Qualifications: O levels/GCSEs or equivalent 0.0 0.0 0.1 0.3 -0.0
Mouth/teeth dental problems: Bleeding gums 3.0 3.9 4.8 -2.2 -1.7
Blood clot in the leg (DVT) 0.4 0.5 0.9 -1.0 -0.3
Medication: Paracetamol 1.4 2.3 3.8 -0.9 -2.0
Headache pain in last month 1.4 2.4 4.6 -0.5 -2.1
Medication for cholesterol, blood pressure or diabetes 3.6 5.9 8.9 1.7 3.0
Glaucoma (self-reported) 0.2 0.3 0.5 -0.2 -0.7
Gout (self-reported) 0.7 1.0 1.8 1.4 0.4
Hypothyroidism/myxoedema (self-reported) 48.5 94.6 151.3 6.2 -12.3
Medication: Amlodipine 0.9 1.3 2.6 -0.0 -1.6
Medication: Ventolin 100micrograms inhaler 1.5 2.0 2.6 1.2 1.6
Birth weight 1.8 4.0 7.7 -0.5 2.8
Chronic bronchitis/emphysema (mother) 2.0 2.4 3.2 -1.8 -1.3
High blood pressure (siblings) 1.6 2.3 3.4 -1.8 1.1
Forced vital capacity (FVC), Best measure 0.1 0.4 0.7 0.9 -0.1
Body fat percentage 1.0 4.1 7.0 -1.1 -2.6
Leg fat percentage (right) 1.0 3.6 6.3 -1.0 -2.5
Arm fat-free mass (right) 0.3 1.6 2.3 1.0 -1.5
Exposure to tobacco smoke outside home 1.6 2.1 4.3 -0.0 2.1
Comparative body size at age 10 1.0 2.6 4.0 2.0 -1.1
Number of full brothers 0.7 0.9 1.5 -0.5 1.2
Worry too long after embarrassment 3.7 6.3 11.1 -1.2 3.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.1 0.2 0.3 0.6 0.1
Wheeze or whistling in the chest in last year 0.2 0.4 0.7 -0.8 0.4
Number of children fathered 1.1 1.2 2.1 1.5 0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.1 1.5 1.2 -0.8
Age at first live birth 0.2 0.4 0.5 0.7 0.6
Pulse wave peak to peak time 2.1 2.5 5.0 0.3 -2.2
Health satisfaction 1.3 1.7 3.3 -0.3 -1.8
Shortness of breath walking on level ground 3.0 3.6 7.1 -0.2 -2.7
Qualifications: College or University degree 0.1 0.3 0.5 0.4 -0.7
Eye problems/disorders: None of the above 0.6 0.7 1.2 1.1 0.3
Mouth/teeth dental problems: Loose teeth 2.8 3.3 5.5 2.4 -1.0
Emphysema/chronic bronchitis 2.8 3.2 3.8 -2.0 -1.6
Medication for pain relief, constipation, heartburn 3.2 5.5 6.9 2.6 2.0
Neck or shoulder pain in last month 0.4 0.6 0.9 -0.6 -1.0
Medication: Blood pressure 1.5 2.7 3.4 -1.4 -1.8
Angina (self-reported) 1.7 2.3 3.2 1.2 -1.8
Migraine (self-reported) 0.5 0.7 1.0 0.5 -1.0
Medication: Ibuprofen 0.5 0.6 0.8 -0.7 -0.9
Medication: Allopurinol 1.5 2.0 2.9 1.7 1.1
Medication: Omeprazole 2.2 2.6 4.0 -2.0 -1.1
Medication: Seretide 50 evohaler 0.2 0.3 0.3 -0.6 0.5
Mean time to correctly identify matches 2.2 4.2 8.2 0.4 2.9
Heart disease (mother) 1.2 1.5 3.0 0.2 -1.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 3.1 3.7 5.4 -2.3 1.4
Whole body fat mass 0.9 3.6 6.9 -0.5 -2.6
Leg fat mass (right) 1.0 3.9 7.7 -0.2 -2.8
Arm predicted mass (right) 0.3 1.6 2.3 1.0 -1.5
Pulse rate, automated reading 0.6 2.0 2.3 -1.3 -1.5
Alcohol intake frequency. 3.7 8.5 9.5 2.7 -3.1
Comparative height size at age 10 0.5 2.7 3.3 1.8 -1.4
Number of full sisters 0.1 0.1 0.2 0.2 -0.4
Suffer from ‘nerves’ 0.1 0.2 0.3 -0.5 0.2
Overall health rating 4.4 9.5 18.1 -1.0 -4.3
Chest pain or discomfort 2.5 3.7 7.1 0.4 -2.7
Had major operations 0.4 0.4 0.8 0.9 -0.3
Age at last live birth 0.2 0.3 0.6 -0.1 0.8
Family relationship satisfaction 0.4 0.5 0.8 0.4 0.9
Leg pain on walking 0.6 0.7 1.0 -0.6 -1.0
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.3 0.6 -0.8 0.2
Commuting to job workplace: Car/motor vehicle 2.4 2.7 4.0 1.2 2.0
Illness, injury, bereavement, stress in last 2 years 3.7 4.5 8.5 2.9 0.7
Medication: Aspirin 1.9 2.4 4.5 -0.6 -2.1
Supplements: Vitamin C 0.0 0.0 0.0 -0.1 0.0
Knee pain experienced in last month 0.4 0.6 1.3 -0.1 -1.1
Hypertension (Self-reported) 0.3 0.8 1.4 -1.2 -0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.2 1.4 1.4 -1.2 -1.1
Illnesses of father: Heart disease 1.9 2.6 4.4 -0.9 -2.1
Illnesses of siblings: Diabetes 0.3 0.4 0.6 -0.5 -0.8
Smoking status: Previous 0.7 1.0 2.0 0.1 1.4
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 0.9 -0.7 0.9
Whole body fat-free mass 0.3 2.0 2.2 1.3 -1.5
Leg fat-free mass (right) 0.6 3.0 4.5 1.2 -2.1
Arm fat percentage (left) 0.9 3.7 7.2 -0.5 -2.7
Average weekly red wine intake 0.0 0.0 0.1 0.3 -0.1
Handedness (chirality/laterality): Left-handed 0.2 0.2 0.4 0.1 0.6
Mood swings 0.5 0.8 1.2 -1.1 -0.7
Loneliness, isolation 1.5 2.1 4.2 0.2 -2.0
Long-standing illness, disability or infirmity 10.2 15.6 29.4 1.4 -5.4
Ever had bowel cancer screening 1.2 1.4 2.6 -1.6 -0.5
Diabetes diagnosed by doctor 2.5 4.2 8.3 0.2 -2.9
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.9 1.0 -1.0 0.8
Friendships satisfaction 0.2 0.2 0.5 0.0 -0.7
Qualifications: nursing, teaching 0.6 0.9 1.4 0.7 -1.2
Commuting to job workplace: Walk 0.0 0.0 0.0 0.0 0.1
Eye problems/disorders: Cataract 0.1 0.1 0.2 -0.4 0.2
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 0.3 -0.4 0.5
Medication for cholesterol 1.1 1.7 2.7 0.8 1.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.5 0.6 1.2 0.0 -1.1
Back pain experienced in last month 0.6 0.8 1.6 -1.3 -0.2
Mineral and other dietary supplements 2.9 3.8 7.4 2.7 -0.5
Breast cancer (self-reported) 1.4 1.6 3.2 1.8 0.2
Asthma (self-reported) 0.2 0.4 0.7 0.8 0.3
Osteoporosis (self-reported) 0.3 0.4 0.5 -0.5 0.7
Osteoarthritis (self-reported) 0.8 1.0 1.7 1.3 -0.7
Medication: Aspirin 2.3 3.0 5.9 -0.2 -2.4
Medication: Gliclazide 1.2 1.3 1.7 0.9 -1.3
Illnesses of father: None of the above (group 1) 1.3 1.6 3.2 1.8 -0.0
Smoking status: Current 0.2 0.3 0.4 -0.5 0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 0.8 0.5 -0.9
Whole body water mass 0.4 2.4 2.7 1.4 -1.6
Leg predicted mass (right) 0.6 3.1 4.6 1.2 -2.1
Arm fat mass (left) 0.8 3.2 6.5 -0.1 -2.5
Number of self-reported non-cancer illnesses 2.1 3.7 7.1 0.4 -2.7
Average weekly champagne plus white wine intake 0.5 0.7 1.2 -0.3 1.1
Miserableness 0.4 0.7 0.7 -0.8 -0.8
Guilty feelings 0.2 0.3 0.4 0.7 -0.5
Wears glasses or contact lenses 3.6 4.1 4.8 1.9 -2.2
Ever taken oral contraceptive pill 1.5 1.7 3.3 0.2 -1.8
Hearing aid user 0.9 1.0 1.8 -1.3 -0.5
Mother’s age at death 1.9 2.4 3.2 -1.2 1.8
Financial situation satisfaction 0.2 0.3 0.6 -0.1 -0.8
Tinnitus: Yes, now most or all of the time 0.0 0.0 0.0 -0.2 0.1
Commuting to job workplace: Public transport 0.9 1.1 2.2 -0.1 -1.5
Eye problems/disorders: Glaucoma 0.0 0.0 0.0 -0.2 0.2
Medication: Blood pressure 0.1 0.2 0.5 -0.7 -0.1
Pain type(s) experienced in last month: Hip pain 0.7 0.9 1.7 -1.3 -0.3
Supplements: Fish oil (including cod liver oil) 0.5 0.7 1.2 -1.1 0.4
High cholesterol (Self-reported) 1.2 2.2 2.7 -1.6 -1.3
Medication: Bendroflumethiazide 1.8 2.7 5.4 -2.3 0.3
Medication: Paracetamol 0.8 1.2 1.3 -1.1 -1.1
Medication: Lisinopril 0.7 1.0 1.9 -1.4 0.1
Medication: Atorvastatin 2.3 2.9 3.1 1.8 -1.6
Illnesses of father: High blood pressure 0.5 0.6 0.9 -0.9 0.5
Alcohol drinker status: Never 4.4 5.3 9.8 0.9 -3.1
Ever smoked 1.2 2.2 4.3 0.2 2.1
Basal metabolic rate 0.5 2.5 3.6 1.2 -1.9
Leg fat percentage (left) 1.1 3.8 6.3 -1.2 -2.5
Arm fat-free mass (left) 0.3 1.6 2.0 1.1 -1.4
Number of operations (self-reported) 1.0 1.4 2.1 -1.4 0.9
Average weekly beer plus cider intake 0.7 0.9 1.4 1.2 0.7
Irritability 0.1 0.2 0.2 -0.4 -0.4
Risk taking 1.3 1.9 3.7 0.4 -1.9
Ever had prostate specific antigen (PSA) test 0.6 0.7 1.4 -0.1 -1.2
Fractured/broken bones in last 5 years 0.4 0.5 0.5 -0.7 -0.7
Age started oral contraceptive pill 0.2 0.3 0.4 0.6 -0.4
Diastolic blood pressure, automated reading 0.8 2.6 2.9 -1.7 1.5
Ever depressed for a whole week 1.1 1.3 2.0 -0.8 -1.4
Unable to work because of sickness or disability 1.3 1.7 3.3 -0.2 -1.8
Commuting to job workplace: Cycle 0.4 0.4 0.9 0.2 0.9
Myopia 1.1 1.6 2.7 0.8 -1.6
Vascular/heart problems diagnosed by doctor 0.3 1.0 1.5 0.7 1.2
Cholesterol lowering medication 0.1 0.1 0.2 -0.4 -0.1
Medication: Omeprazole (e.g. Zanprol) 2.4 2.9 5.0 -2.2 -1.0
Pain experienced in last month 0.8 1.3 2.1 1.5 -0.7
Supplements: Calcium 1.7 1.9 2.0 -1.4 -1.4
Basal cell carcinoma (self-reported) 1.5 1.8 2.0 -1.2 1.4
Heart attack/myocardial infarction (self-reported) 2.3 3.0 5.2 -0.8 -2.3
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 0.7 -0.8 -0.5
Heart disease (siblings) 0.5 0.7 1.2 -1.1 -0.4
Alcohol drinker status: Previous 0.6 0.7 1.3 0.4 -1.1
Pack years of smoking 0.6 1.0 1.2 -0.8 -1.1
Impedance of whole body 0.8 4.0 4.7 -1.8 2.2
Leg fat mass (left) 0.9 3.6 7.2 -0.3 -2.7
Arm predicted mass (left) 0.4 1.9 2.8 1.0 -1.7