Hub : Genes

RUFY1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1850	0.0510	1.3e-04	0.135	NA	0.126	NA	0.133	3.5e-11	NA	1.8e-10	NA	5.4e-11
2	GTEx	Artery Aorta	0.1540	0.0590	4.3e-03	0.024	NA	0.133	NA	0.032	1.6e-02	NA	8.6e-08	NA	6.6e-03
3	GTEx	Artery Tibial	0.3232	0.0667	4.3e-06	0.113	NA	0.094	NA	0.109	3.8e-09	NA	8.0e-08	NA	6.7e-09
4	GTEx	Brain Cerebellum	0.3570	0.1160	5.4e-03	0.008	NA	-0.010	NA	0.024	1.8e-01	NA	9.5e-01	NA	6.5e-02
5	GTEx	Breast Mammary Tissue (Female)	0.3290	0.1292	2.0e-02	-0.005	NA	0.020	NA	0.026	4.9e-01	NA	8.4e-02	NA	5.6e-02
6	GTEx	Cells Transformed fibroblasts	0.3260	0.0520	4.1e-14	0.178	NA	0.291	NA	0.276	2.6e-13	NA	4.3e-22	NA	8.1e-21
7	GTEx	Esophagus Mucosa	0.2550	0.0540	1.1e-07	0.193	NA	0.249	NA	0.184	5.6e-13	NA	1.0e-16	NA	2.2e-12
8	GTEx	Nerve Tibial	0.2304	0.0645	1.4e-04	0.129	NA	0.131	NA	0.142	2.0e-09	NA	1.7e-09	NA	3.0e-10
9	GTEx	Thyroid	0.1950	0.0530	2.6e-04	0.186	NA	0.183	NA	0.180	3.2e-14	NA	5.4e-14	NA	8.7e-14
10	GTEx	Whole Blood	0.1270	0.0380	2.1e-04	0.086	NA	0.066	NA	0.081	2.7e-08	NA	9.8e-07	NA	6.5e-08
11	METSIM	Adipose	0.0655	0.0224	2.7e-04	0.009	0.025	0.017	0.024	0.021	1.2e-02	1.1e-04	1.3e-03	1.2e-04	3.2e-04
12	NTR	Blood	0.0684	0.0144	1.4e-11	0.068	0.047	0.066	0.066	0.068	4.4e-21	5.5e-15	1.5e-20	2.4e-20	6.1e-21
13	ROSMAP	Brain Pre-frontal Cortex	0.2917	0.0457	1.1e-10	0.179	0.130	0.178	0.186	0.180	1.9e-22	2.3e-16	2.3e-22	2.6e-23	1.5e-22
14	YFS	Blood	0.2474	0.0256	0.0e+00	0.210	0.216	0.244	0.239	0.240	8.4e-67	6.3e-69	6.0e-79	3.5e-77	2.6e-77
15	TCGA	Head and Neck Squamous Cell Carcinoma	0.0274	0.0138	8.9e-04	0.012	0.022	0.023	NA	0.017	1.3e-02	1.4e-03	1.1e-03	NA	4.5e-03
16	TCGA	Brain Lower Grade Glioma	0.0593	0.0336	6.1e-03	0.009	0.018	0.010	NA	0.004	2.9e-02	3.6e-03	2.2e-02	NA	9.3e-02
17	TCGA	Liver Hepatocellular Carcinoma	0.1890	0.0950	4.9e-03	0.022	0.026	-0.002	NA	0.012	3.2e-02	2.2e-02	4.3e-01	NA	8.4e-02
18	TCGA	Stomach Adenocarcinoma	0.0700	0.0370	3.3e-03	0.032	0.031	0.020	NA	0.037	2.2e-03	2.5e-03	1.3e-02	NA	1.1e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Bipolar Disorder (2018)	0.9	1.4	3.7	-1.7	-1.7	-0.8	0.9	0.4	-1.2	-1.9	-0.9	-1.6	1.2	-0.9	1.1	1.3	1.1	-1.5	-0.2	0.3	-1.0
Bipolar Disorder or Schizophrenia	1.4	3.4	9.9	-2.7	-1.0	-1.9	-0.1	-0.7	-1.8	-3.1	-2.0	-2.2	2.2	-0.7	2.2	-0.1	2.1	-2.3	-1.5	-1.1	-1.7
Depressed Affect (Nagel 2018)	0.3	0.7	3.5	-0.7	-0.9	-0.1	1.0	-0.5	-1.6	-0.8	-0.0	-0.7	0.9	0.2	0.7	0.8	0.8	-0.5	0.4	1.9	-0.3
Depression (Nagel 2018)	0.2	0.3	1.4	0.1	-1.2	-0.4	-0.4	-0.6	-0.5	-0.4	0.0	-0.5	0.3	0.5	0.3	0.4	0.4	-0.7	-0.2	1.0	-0.3
Intelligence (Savage-Jansen 2018)	1.6	4.8	10.4	2.9	1.1	2.6	0.9	1.1	2.5	3.2	2.3	2.7	-2.4	-1.8	-2.4	-0.0	-1.6	3.2	1.6	0.2	3.0
Neuroticism (Nagel 2018)	0.3	0.7	2.6	-0.6	-1.3	-0.5	1.0	-1.5	-1.6	-0.8	-0.2	-0.6	0.7	-0.2	0.6	0.2	0.5	-0.6	-0.3	0.9	-1.0
Schizophrenia (2018)	1.2	2.5	5.4	-2.1	0.1	-1.8	-0.9	-1.2	-1.2	-2.3	-1.9	-1.5	1.9	-0.0	1.9	-1.2	1.8	-1.9	-1.7	-1.5	-1.3
Schizophrenia vs Biploar Disorder	0.5	0.6	2.5	-0.3	-0.1	-0.8	-1.5	-1.5	-0.2	-0.5	-0.9	-0.3	-0.0	0.4	0.2	-1.6	0.1	-0.7	-1.2	-0.3	-0.8
Worry (Nagel 2018)	0.4	0.8	2.9	-0.5	-1.6	-1.0	0.6	-1.7	-1.4	-0.7	-0.5	-0.4	0.6	-0.9	0.7	-0.6	0.5	-0.4	-0.4	0.4	-1.0
Alzheimer’s Disease (in mother)	0.7	0.8	2.8	-1.0	1.7	-1.1	-0.5	-1.7	-1.0	-0.9	-0.6	-1.0	0.6	0.5	0.5	0.0	-0.4	-0.4	-0.5	-0.4	-1.1
Alzheimer’s Disease (in father)	0.9	1.0	2.3	-1.1	-0.7	-1.0	-1.0	0.1	-0.1	-1.3	-1.4	-1.1	1.5	0.1	1.5	-1.0	1.4	-0.2	0.2	0.9	0.5
Alzheimer’s Disease (including proxy)	0.3	0.4	2.0	-0.3	1.4	-0.3	-0.5	-0.5	-0.7	-0.5	-0.1	-0.5	0.8	0.7	0.5	0.1	0.0	0.3	0.7	1.0	0.2
Crohns Disease (2017)	0.6	1.4	4.5	-1.0	1.0	-0.4	0.6	-0.4	-2.1	-1.5	-0.7	-0.7	2.1	1.3	1.9	-0.1	1.3	-1.5	0.3	0.8	-0.4
Irritable Bowel Disease (IBD)	0.6	1.5	6.2	-0.5	0.4	-0.3	0.2	-0.8	-1.8	-1.3	-0.7	-0.2	2.5	1.1	2.3	-1.1	2.1	-0.7	-0.5	0.4	0.4
Ulcerative Colitis (UC)	0.5	0.8	3.4	-0.1	0.3	-0.3	0.2	-1.2	-1.0	-0.6	-0.5	-0.1	1.9	0.8	1.7	-0.9	1.4	-0.3	-1.1	-0.9	0.1
Major Depression (MDD)	5.7	7.0	17.5	-3.1	-0.9	-3.6	-0.9	-2.6	-1.9	-3.1	-3.0	-3.4	2.1	-1.3	2.3	-1.0	0.8	-4.2	-3.3	-1.9	-3.9
Reaction Time	0.4	0.7	2.5	0.7	-1.6	0.6	-0.4	-0.0	1.3	0.9	0.5	1.0	-1.3	0.4	-1.0	-0.1	-0.7	1.5	-0.3	0.4	0.1
Verbal and Numeric Reasoning (VNR)	2.0	4.7	11.1	3.3	1.2	2.6	0.3	0.6	1.9	3.3	2.3	3.0	-2.2	-1.6	-2.4	-0.7	-1.2	2.5	2.2	0.7	3.1
Breast Cancer	1.5	3.6	9.2	-2.9	-1.5	-2.0	-1.3	-1.0	-0.9	-2.2	-2.9	-3.0	1.6	-0.0	1.8	-1.3	1.0	-1.9	-2.2	-2.0	-1.5
Ovarian Cancer	1.4	1.8	6.7	-1.2	-0.4	-1.7	-1.7	-1.0	-0.7	-1.4	-1.9	-1.0	1.5	0.4	1.7	-2.6	1.6	-0.9	-1.5	0.3	-0.1
Prostate Cancer	1.3	1.9	3.8	-1.7	-1.9	-1.7	0.0	-0.8	-0.7	-1.8	-1.7	-1.6	1.3	-1.3	1.5	-1.2	1.7	-1.1	-1.4	0.1	-1.1
Age at First Birth	1.0	1.4	3.5	1.9	1.5	1.5	-0.3	0.2	0.9	1.6	1.6	1.8	-1.2	-0.1	-1.3	0.5	-0.8	1.3	0.9	0.8	1.1
Bipolar Disorder (2011)	0.0	0.0	0.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.3	0.6	0.1	-0.1	0.6
Body Mass Index (BMI) (2010)	0.4	0.6	4.0	0.1	0.4	0.1	-2.0	0.4	1.3	0.2	0.2	0.6	-0.8	-0.6	-0.7	-0.3	-0.2	1.0	0.1	1.1	0.8
Coronary Artery Disease (CAD)	0.3	0.3	2.4	-0.6	1.5	-0.4	-0.2	0.1	0.2	0.0	-0.4	-0.4	-0.4	0.5	-0.6	0.4	-0.4	-0.4	-0.4	-0.8	0.0
Crohns Disease (2012)	1.0	1.6	4.3	-1.2	-0.3	-0.5	-0.9	0.3	-1.9	-1.6	-1.1	-1.0	2.1	1.9	2.0	-0.5	1.7	-1.4	0.2	0.8	-0.5
Mean Putamen Volume	0.9	1.0	2.5	-1.3	-0.7	-0.5	1.2	1.6	-1.1	-1.5	-0.5	-1.6	0.9	0.2	0.8	0.8	1.0	-1.4	0.9	0.3	-0.4
Fasting Glucose	0.6	0.7	2.6	-0.4	-0.2	0.3	-0.2	0.5	1.1	0.6	-0.2	-0.6	-1.6	-1.2	-1.3	0.2	-1.5	1.4	-0.1	-0.1	-0.4
HbA1C	1.5	1.7	3.6	1.6	0.4	1.6	1.9	0.3	0.9	1.2	1.8	1.5	-1.4	-0.3	-1.5	1.6	-1.3	0.9	1.8	0.2	0.8
HDL Cholesterol	1.0	1.7	4.2	2.0	1.0	1.5	1.0	0.5	0.7	1.4	1.7	1.7	-0.9	-1.4	-1.2	0.7	-0.6	1.8	1.6	0.8	1.5
LDL Cholesterol	0.2	0.4	2.0	-0.3	0.7	-0.6	-0.0	0.6	1.1	0.0	-0.6	-0.0	0.0	1.4	0.1	-1.0	0.3	0.0	-0.4	-0.2	0.4
Lupus	0.8	1.3	3.9	-1.4	-0.4	-0.8	-1.1	-0.7	-2.0	-1.9	-0.8	-1.4	1.3	0.4	1.1	0.2	0.6	-1.8	0.0	0.1	-1.4
Neuroticism (2016)	0.2	0.3	1.3	-0.2	-1.1	-0.2	0.6	0.0	-0.3	-0.3	-0.2	-0.1	0.1	-1.0	0.1	-0.6	0.4	-0.1	0.1	1.0	0.1
Primary Biliary Cirrhosis	0.2	0.3	1.4	-0.0	0.7	-0.0	0.4	0.2	-0.4	-0.2	-0.0	0.0	0.2	1.2	0.1	0.4	-0.0	-1.1	-0.9	-0.0	-0.7
Rheumatoid Arthritis	0.3	0.4	2.4	-0.2	1.5	-0.7	-0.6	0.1	1.2	0.4	-0.5	0.0	-0.3	0.9	-0.1	-0.8	-0.1	0.0	-0.8	0.1	0.1
Schizophrenia (2014)	1.0	2.1	4.6	-1.5	-0.3	-1.4	-0.4	-1.1	-1.4	-2.1	-1.3	-1.2	1.9	0.1	1.9	-0.6	1.9	-2.1	-1.6	-1.4	-1.7
Triglycerides	0.9	1.4	3.0	-1.0	-1.2	-1.0	-1.2	-0.4	-0.7	-1.3	-1.2	-0.6	1.4	1.1	1.5	-1.6	1.7	-1.7	-1.3	0.5	-0.5
Type 2 Diabetes (T2D) (2012)	0.4	0.5	4.1	-0.3	-1.4	-0.3	2.0	-0.7	-0.8	-0.8	-0.2	-0.1	0.2	-0.1	0.4	0.1	0.5	-0.4	-0.2	0.1	-0.7
Ulcerative Colitis	1.0	1.5	5.4	-0.8	-0.5	-0.8	-0.7	0.6	-0.4	-1.2	-1.2	-0.7	2.1	1.1	2.3	-1.6	2.2	-0.7	-1.0	-0.3	-0.1
Blood Eosinophil Count	0.3	2.6	5.4	2.3	1.4	1.9	-1.0	0.2	1.3	2.2	2.1	2.2	-2.3	0.5	-2.3	0.7	-1.6	1.4	0.6	1.1	1.4
Blood Platelet Count	0.3	3.4	9.9	-1.4	0.2	-1.2	1.0	-1.9	-3.1	-2.5	-0.7	-1.6	2.0	1.6	1.9	1.0	0.9	-2.9	-1.6	0.6	-3.1
Blood Red Count	0.8	7.5	19.4	4.0	2.5	3.4	1.6	0.8	2.4	3.6	3.7	4.4	-2.6	-1.2	-2.9	1.4	-1.8	3.4	2.5	1.1	2.4
Blood White Count	0.5	3.6	12.5	-1.4	0.5	-1.2	0.2	-2.6	-3.5	-1.8	-0.4	-1.6	1.3	2.6	0.9	1.9	-0.2	-3.5	-0.7	-1.0	-3.1
Heel T-Score	0.2	1.9	10.1	-0.9	-0.1	-1.5	0.2	-2.1	-0.4	-1.1	-0.6	-1.8	-0.2	0.6	-0.0	1.2	-1.1	-1.4	-2.2	-1.4	-3.2
BMI	2.2	12.5	22.5	3.8	4.7	4.7	-0.7	2.7	3.3	4.4	4.2	4.4	-3.9	0.7	-4.2	2.5	-2.9	4.1	3.0	2.6	3.5
Height	0.3	6.6	18.0	3.1	-0.9	2.4	-1.9	3.8	3.8	2.8	1.4	2.9	-2.1	-0.8	-1.8	-2.9	-0.4	3.8	0.6	0.7	4.2
Waist Hip Ratio (WHR)	0.2	1.1	2.8	1.3	-0.1	0.4	-0.5	1.4	1.4	1.7	0.6	1.1	-1.1	0.6	-1.1	-1.1	-0.7	1.6	0.1	0.5	1.3
Systolic Blood Pressure	0.3	1.7	7.5	-0.8	-0.5	-0.5	2.3	-1.2	-2.7	-1.6	-0.0	-1.0	1.6	-0.2	1.3	1.3	1.3	-1.5	0.4	0.4	-1.0
Smoking Status	0.5	1.2	3.3	1.3	1.4	1.3	0.7	1.3	0.4	0.8	1.4	1.7	-0.4	0.2	-0.6	0.6	0.1	1.3	1.3	1.1	1.8
Allergy or Eczema	0.4	1.2	3.3	1.8	0.8	1.4	-0.3	-0.4	0.7	1.6	1.6	0.9	-1.2	0.1	-1.3	1.1	-1.5	0.0	1.0	1.0	-0.1
Cardiovascular Disease	0.1	0.3	1.6	-0.1	-0.4	0.0	1.1	0.5	-0.4	-0.4	0.2	-0.6	-0.1	1.2	-0.2	1.1	-0.2	-0.2	0.5	0.5	-0.5
Hypothyroidism (self reported)	0.2	0.5	3.4	-0.8	-1.9	0.1	-0.8	0.3	0.2	-0.8	-0.7	-0.8	0.3	-0.7	0.4	-0.8	0.6	0.9	-0.2	-0.0	0.6
Respiratory disease	1.8	3.9	12.2	2.1	0.1	1.6	-1.9	0.4	2.6	2.6	1.4	1.9	-2.9	-1.9	-2.7	-0.6	-2.3	3.5	0.0	0.2	2.0
Type 2 Diabetes (T2D) (2018)	0.4	0.7	2.7	-0.1	0.2	0.4	0.3	1.5	1.6	0.4	0.3	-0.2	-1.4	-0.9	-1.2	0.8	-0.7	0.6	-0.5	0.5	0.5
Lung FEV1/FVC ratio	0.5	2.6	10.0	1.2	2.4	1.5	1.6	-0.1	0.9	1.7	1.7	1.3	-1.2	-3.2	-1.4	2.2	-1.7	1.4	1.7	0.6	-0.0
Lung FVC	1.0	5.1	11.9	-3.2	-0.7	-2.8	1.1	-0.9	-1.5	-3.0	-2.4	-3.4	2.6	1.9	2.4	0.6	1.1	-3.0	-1.6	-1.9	-2.9
Neuroticism	0.2	0.5	3.2	0.1	-0.6	-0.0	1.2	-0.7	-0.8	0.1	0.5	0.4	-0.4	-1.8	-0.5	0.3	-0.3	0.4	0.5	0.7	-0.1
Chronotype (morning person)	1.8	4.1	8.6	2.8	1.3	2.5	-0.6	2.4	1.8	2.2	2.6	2.9	-1.5	-1.1	-1.6	0.5	-0.7	1.7	2.4	2.4	2.6
Hair Pigment	0.0	0.4	1.6	-1.0	-0.1	-0.6	1.3	-0.5	-0.6	-0.9	-0.2	-1.0	-0.5	-0.8	-0.4	0.5	-0.3	-0.7	-0.0	0.2	-0.6
Tanning	0.1	1.4	4.4	1.2	0.8	1.8	0.5	1.3	1.4	1.7	1.0	1.4	-0.6	0.3	-0.5	-0.3	0.3	2.1	0.8	-0.3	2.0
Hand grip strength (left)	0.8	2.1	5.4	-2.3	-1.6	-1.3	-1.0	0.5	-0.5	-2.3	-2.0	-1.8	1.9	-0.7	2.0	-1.2	1.9	-0.6	0.2	0.0	-0.1
Number of treatments/medications taken	0.3	0.5	1.6	0.8	1.3	0.7	-0.3	0.1	0.3	0.8	0.7	0.8	-0.1	0.7	-0.2	0.0	-0.2	1.0	0.9	1.0	0.7
Average weekly spirits intake	0.7	0.9	2.2	0.9	0.6	1.2	0.3	1.0	1.0	0.9	0.8	1.1	-0.8	-0.9	-0.8	-0.1	-0.2	1.2	1.5	1.1	1.4
Sensitivity / hurt feelings	0.3	0.5	3.1	-0.4	0.4	-0.0	1.8	-1.4	-1.0	-0.3	0.2	-0.1	-0.3	-0.7	-0.4	0.8	-0.5	-0.1	-0.1	-0.4	-0.9
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.8	-0.5	-0.5	-0.8	-0.5	0.2	0.6	-0.6	-0.6	-0.9	0.3	-0.0	0.5	-0.3	0.7	-0.3	-0.6	0.5	-0.2
Hearing difficulty/problems: Yes	0.2	0.3	1.3	0.2	0.6	0.3	-0.8	0.3	0.7	0.5	0.2	0.1	-0.9	-0.7	-0.9	0.2	-1.1	-0.2	-0.2	0.9	0.0
Relative age of first facial hair	2.2	4.5	10.4	3.2	0.8	2.5	0.2	2.2	2.5	2.7	2.3	3.0	-1.7	-1.0	-1.7	-0.1	-0.3	2.8	2.0	1.7	3.2
Other serious medical condition/disability diagnosed by doctor	0.7	1.0	2.6	-1.4	-0.4	-1.3	-0.6	-0.2	0.2	-1.1	-1.3	-1.6	0.1	-0.0	0.2	-0.6	-0.6	-0.6	-1.6	-1.5	-1.2
Ever used hormone-replacement therapy (HRT)	0.6	0.8	4.6	-0.7	-1.2	-0.3	-0.6	0.5	-0.7	-0.8	-0.6	-0.4	1.0	2.2	1.2	-0.5	0.7	-0.6	-0.1	-0.6	-0.9
Ever had hysterectomy (womb removed)	1.5	1.7	3.7	-1.3	1.1	-1.3	-1.0	-1.4	-1.9	-1.5	-1.3	-1.1	1.7	0.2	1.8	-1.0	0.9	-1.7	-1.0	-0.6	-1.4
Systolic blood pressure, automated reading	0.2	0.5	1.2	-0.7	-0.7	-0.3	0.2	0.6	-0.8	-1.0	-0.1	-0.8	1.0	-0.0	0.9	0.8	1.0	-0.9	0.2	1.1	-0.0
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.4	1.1	-0.2	0.5	-1.2	0.6	0.7	0.7	1.0	1.0	-0.8	0.7	-0.8	0.6	-0.3	1.1	1.0	1.6	1.0
Angina	0.8	1.0	3.3	-1.0	1.5	-0.6	-0.5	-1.3	-0.8	-0.9	-0.8	-0.6	0.8	1.8	0.8	-0.1	0.0	-1.8	-0.7	-0.5	-1.3
Medication for hormone replacement therapy	2.5	2.8	10.0	-1.7	-1.7	-1.5	0.2	-2.6	-2.2	-1.9	-1.1	-2.2	0.7	0.6	0.7	1.0	-0.3	-2.1	-0.7	-1.9	-3.2
Vitamin and mineral supplements	0.5	0.6	1.8	-0.4	0.6	-0.6	-1.0	0.3	0.7	0.6	-0.4	-0.8	-1.0	-0.6	-1.0	0.3	-1.3	0.8	-1.2	-1.4	-0.3
Supplements: Zinc	0.6	0.7	2.5	-0.4	-1.4	-0.6	-1.4	0.5	0.6	-0.6	-0.8	-0.0	0.4	0.9	0.6	-1.6	1.1	0.0	-0.2	0.3	1.0
Medication: Co-codamol	0.6	0.7	1.9	1.0	1.1	0.6	-0.7	-0.3	1.0	1.1	0.6	1.4	-0.5	-1.3	-0.3	-0.6	-0.1	1.3	-0.6	-0.5	0.5
Medication: Metformin	0.5	0.7	2.6	0.4	0.8	0.3	0.3	0.6	1.2	0.8	0.5	0.2	-1.6	-0.5	-1.4	0.7	-1.2	1.1	-0.3	-0.1	0.1
Diabetes (father)	1.9	2.3	7.8	0.6	-0.3	1.1	0.8	1.7	2.8	1.5	0.9	0.4	-2.8	-1.0	-2.6	0.9	-1.7	2.1	0.2	0.9	1.2
Diabetes (mother)	3.1	3.9	8.5	2.5	1.8	2.4	0.9	0.4	1.1	2.6	2.5	2.5	-2.4	-0.5	-2.5	1.5	-2.2	2.9	1.8	0.7	1.4
Severe depression (siblings)	0.5	0.6	3.1	-0.4	-0.6	-0.8	-1.8	-0.6	-0.8	-0.7	-0.6	-0.6	-0.0	-1.3	0.1	-1.1	0.4	-0.4	-1.0	0.1	-0.0
Pack years adult smoking proportion	0.6	1.0	2.9	1.2	1.0	0.7	-1.2	0.0	1.1	1.3	0.9	1.7	-1.0	1.0	-1.0	-0.4	-0.6	1.0	0.3	0.4	1.1
Impedance of leg (right)	0.3	1.3	6.7	1.2	-1.0	0.5	2.6	-0.6	-1.5	0.5	0.7	0.9	0.7	-2.1	0.6	-0.7	0.8	0.8	0.6	1.1	1.1
Leg fat-free mass (left)	0.3	1.5	7.8	0.6	1.2	1.0	-1.3	1.4	2.8	1.1	0.3	1.1	-1.5	0.8	-1.4	-0.6	-0.7	1.6	0.2	0.0	1.5
Trunk fat percentage	3.9	15.5	30.5	4.8	3.7	5.5	0.7	2.8	3.4	5.2	4.9	5.2	-3.9	0.7	-4.3	2.3	-2.9	5.0	3.6	2.9	4.5
Hand grip strength (right)	1.4	3.7	8.2	-2.9	-2.8	-1.9	-1.6	0.9	-0.3	-2.7	-2.8	-2.5	2.2	-0.7	2.4	-2.0	2.3	-1.3	-0.2	-0.5	-0.2
Townsend deprivation index at recruitment	1.2	1.8	3.6	1.7	0.8	1.4	1.4	1.2	0.9	1.3	1.9	1.7	-1.4	1.2	-1.4	1.5	-1.0	0.8	1.3	1.6	0.6
Current tobacco smoking	0.4	0.7	2.3	1.5	0.3	1.0	0.2	0.9	-0.2	1.0	1.2	1.5	-0.7	0.3	-0.7	0.1	-0.3	0.5	0.2	1.1	1.1
Average weekly fortified wine intake	0.6	0.7	2.4	-0.3	0.9	0.2	0.7	-0.9	-1.3	-1.1	0.2	-0.0	1.6	0.4	1.3	0.5	0.8	-1.3	0.1	-0.2	-1.0
Maternal smoking around birth	0.4	0.6	1.8	-0.8	0.1	-0.5	0.2	-0.7	-1.4	-0.9	-0.4	-0.6	0.5	1.1	0.5	0.7	-0.1	-1.1	-0.5	-0.4	-1.3
Fed-up feelings	0.3	0.5	3.4	-0.5	-0.5	-0.3	-0.1	-0.1	-1.1	-0.9	-0.1	-0.3	0.9	-0.1	0.8	-0.2	1.0	-0.5	0.2	1.8	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	4.8	1.7	-0.2	1.3	0.1	0.1	0.5	1.1	1.5	1.3	-0.9	-0.7	-1.0	0.9	-0.5	0.6	1.1	2.2	0.7
Relative age voice broke	4.0	6.2	12.0	2.9	1.8	2.6	1.9	2.1	3.2	3.5	2.6	2.7	-3.2	-2.6	-3.1	1.1	-2.4	2.8	1.4	-0.0	2.2
Taking other prescription medications	0.3	0.4	2.1	0.1	0.4	0.2	-1.5	-0.2	1.0	0.6	-0.2	0.3	-0.2	-0.2	-0.2	-1.0	-0.3	1.2	0.1	-0.1	0.7
Age when periods started (menarche)	3.3	8.0	18.8	4.3	3.8	3.1	0.6	0.5	1.9	4.0	3.7	4.3	-2.3	-1.1	-2.6	0.3	-1.6	3.5	2.5	1.5	3.3
Bilateral oophorectomy (both ovaries removed)	3.0	3.5	8.0	-1.8	-0.8	-1.3	-1.4	-1.2	-2.2	-2.6	-1.8	-1.8	2.7	0.9	2.8	-1.2	2.1	-2.6	-0.9	-1.0	-2.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.1	0.8	0.8	0.4	-0.5	-0.7	0.5	1.2	0.6	0.3	-1.3	-0.3	-1.3	0.7	-1.5	1.0	0.2	0.0	-0.1
Tinnitus: Yes, but not now, but have in the past	1.7	1.8	4.9	1.6	0.3	1.8	1.3	0.9	0.7	1.3	1.6	1.7	-0.6	1.5	-0.8	1.2	-0.2	1.2	2.2	1.8	1.2
Qualifications: CSEs or equivalent	0.6	0.8	5.6	-0.3	-1.7	-1.1	0.6	-2.4	-0.3	-0.5	-0.4	-0.2	-0.1	-0.6	0.0	-0.2	-0.1	0.2	0.0	-0.7	-1.4
Serious illness, injury or assault to yourself	1.2	1.5	4.6	-1.3	-0.8	-1.4	1.6	-0.3	-0.4	-0.6	-0.7	-2.0	-0.8	-0.3	-0.7	1.2	-1.7	-1.1	-1.5	-0.9	-2.1
High blood pressure	0.3	0.7	3.2	0.6	-0.2	0.5	1.2	1.0	0.1	0.1	0.8	-0.1	0.4	1.8	0.2	1.5	0.3	0.0	1.5	1.0	-0.2
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.2	1.1	-0.3	0.8	-0.2	-0.5	0.1	0.9	0.9	0.5	-0.7	0.2	-0.8	0.4	-1.0	-0.2	0.5	0.6	-0.6
Multivitamins +/- minerals	1.2	1.5	5.1	-0.2	-0.5	0.6	1.4	-0.5	-1.3	-1.5	0.1	0.4	1.8	0.8	1.7	-0.1	2.0	-1.2	1.5	2.3	-0.0
Stomach or abdominal pain in last month	0.4	0.5	1.7	-1.0	-0.9	-0.8	1.0	-0.2	-0.6	-0.3	-0.4	-0.9	-0.2	-0.7	-0.0	0.5	-0.7	-0.3	-0.6	-0.6	-1.3
Supplements: Glucosamine	0.7	1.0	2.2	-1.3	-1.1	-1.5	0.3	0.4	0.2	-1.1	-1.5	-1.4	0.8	1.4	1.0	-0.8	0.7	-1.1	-0.5	0.1	-0.7
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	4.2	-0.8	0.4	-0.5	-1.4	-0.1	0.4	0.4	-1.1	-0.0	-0.5	0.5	-0.4	-1.1	-0.7	0.9	-0.9	-2.1	0.3
Medication: Atenolol	0.2	0.3	1.0	-0.4	0.4	-0.3	0.6	0.2	-0.0	-0.2	-0.6	0.1	0.3	0.9	0.4	-1.0	0.5	-0.9	-0.4	0.2	-0.1
Medication: Levothyroxine sodium	0.4	0.6	3.0	0.1	-0.8	1.0	0.3	1.7	1.1	0.3	0.5	-0.0	-0.4	0.3	-0.3	0.8	-0.2	1.3	0.6	1.2	0.4
Sitting height	0.1	0.7	4.4	-0.4	-0.8	-0.3	-0.5	0.5	1.0	-0.6	-1.1	-0.1	0.2	-0.2	0.4	-2.1	1.0	0.3	-1.1	-0.8	1.0
Chronic bronchitis/emphysema (father)	0.5	0.6	2.6	-0.2	-0.1	-0.8	-1.2	-1.1	-0.5	-0.3	-0.8	-0.8	-0.1	0.2	0.0	-1.0	-0.6	-0.5	-0.9	-1.6	-1.1
High blood pressure (mother)	0.6	0.9	2.5	-0.9	-1.1	-0.7	0.4	-1.4	-1.6	-1.2	-0.8	-1.5	0.5	-0.1	0.4	0.2	0.1	-0.9	-0.6	-0.4	-1.4
Body mass index (BMI)	2.1	9.0	16.2	3.2	3.4	4.0	-0.2	2.6	3.3	3.8	3.4	3.7	-3.4	0.7	-3.6	2.0	-2.5	3.6	2.5	1.8	3.1
Impedance of leg (left)	0.3	1.6	6.3	1.7	-0.5	1.2	2.5	-0.2	-1.5	0.9	1.4	1.5	0.4	-2.0	0.2	-0.2	0.4	1.1	1.0	1.4	1.4
Leg predicted mass (left)	0.3	1.5	7.6	0.7	1.2	1.1	-1.3	1.4	2.8	1.1	0.3	1.1	-1.6	0.8	-1.5	-0.5	-0.7	1.6	0.2	0.1	1.5
Trunk fat mass	3.4	14.5	26.9	4.5	3.2	5.2	0.3	3.2	3.9	5.0	4.4	4.9	-4.0	0.5	-4.3	1.7	-2.8	5.1	3.1	2.5	4.6
Waist circumference	3.2	11.7	21.3	3.9	2.8	4.0	0.3	3.5	4.2	4.4	3.7	4.2	-4.1	0.2	-4.2	1.4	-2.8	4.6	2.3	2.4	3.9
Number of incorrect matches in round	5.1	8.4	20.6	-3.6	-4.5	-2.9	-1.4	-0.3	-2.2	-4.2	-3.1	-4.0	3.0	1.4	3.4	-0.8	2.6	-3.3	-2.6	-0.1	-3.4
Past tobacco smoking	0.2	0.3	2.1	-0.3	-1.4	-0.5	-0.6	0.3	0.3	-0.1	-0.7	-0.5	-0.2	-0.7	0.0	-1.0	0.1	-0.0	-0.3	0.4	0.1
Alcohol usually taken with meals	0.8	1.3	4.3	0.9	-0.0	1.1	-1.0	1.5	2.1	1.1	0.8	0.6	-1.6	-1.8	-1.4	0.2	-0.8	0.9	0.4	1.0	1.4
Nervous feelings	0.3	0.5	5.0	0.0	-0.6	-0.1	0.8	0.4	-0.1	0.2	-0.0	0.2	-0.8	-2.2	-0.6	-0.4	-0.2	0.7	0.3	1.0	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	2.1	-0.8	-1.3	-0.9	0.4	0.1	0.7	-0.9	-0.8	-0.8	0.2	-1.4	0.4	-0.8	0.5	-0.8	-1.4	0.2	-0.6
Hearing difficulty/problems with background noise	0.4	0.7	2.6	-0.3	0.2	-0.2	0.4	0.0	0.5	-0.1	0.0	-0.8	-1.6	-0.6	-1.5	0.4	-1.6	-0.7	-1.3	0.9	-0.8
Hair/balding pattern: Pattern 2	1.1	1.3	3.0	1.4	1.0	1.3	-0.2	1.5	1.3	1.2	1.2	1.7	-1.1	-1.0	-1.0	-0.3	-0.3	1.2	0.8	1.4	1.5
Had menopause	1.3	1.6	5.9	1.5	0.8	1.6	0.5	2.4	0.2	1.2	1.5	1.3	-0.7	1.1	-0.8	0.8	-0.2	1.2	1.5	1.6	1.8
Had other major operations	0.7	0.9	4.5	-0.7	-2.1	-0.5	0.6	0.9	-0.1	-1.3	-1.0	-1.2	0.3	0.5	0.5	-0.3	0.4	-1.7	-0.6	0.4	-0.9
Forced vital capacity (FVC)	1.0	3.8	8.8	-2.9	-1.7	-2.7	0.4	-1.4	-0.5	-2.6	-2.8	-3.0	1.4	0.6	1.4	-1.0	0.4	-1.7	-2.3	-2.4	-2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	1.5	-0.1	0.5	-0.4	-0.1	-0.8	0.2	0.2	-0.1	-0.3	-0.3	-0.2	-0.3	0.1	-0.5	0.2	-0.6	-1.2	-0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	2.1	0.3	0.7	0.6	0.6	0.7	-0.3	0.3	0.6	0.6	-0.3	0.3	-0.5	0.3	0.1	-0.2	1.0	1.4	0.7
Qualifications: None of the above	0.5	1.1	2.9	1.4	1.7	1.5	0.4	0.4	-0.7	0.8	1.6	1.6	0.3	1.0	0.0	1.5	-0.2	0.3	1.1	1.3	0.6
Financial difficulties in last 2 years	0.4	0.6	1.6	-0.9	0.2	-1.1	-1.2	-0.1	-0.6	-1.0	-0.8	-1.3	0.7	0.1	0.7	0.2	0.6	-0.6	-0.5	1.0	-0.5
Mouth/teeth dental problems	1.3	1.9	6.8	-1.4	-2.6	-1.8	-0.1	1.6	1.4	-1.0	-2.1	-1.5	0.3	-0.5	0.7	-1.9	1.6	0.5	-1.8	-0.3	0.6
Heart attack	0.3	0.3	2.7	0.3	1.6	-0.3	0.8	-0.1	-0.4	0.3	-0.1	0.1	0.2	1.3	0.2	-0.5	-0.0	-0.4	-0.2	-0.4	-0.3
Allergy	0.4	0.8	2.3	-1.1	0.8	-0.7	1.0	0.4	-1.2	-1.4	-0.6	-0.7	1.5	-0.0	1.4	0.5	1.3	-0.7	0.4	-0.2	-0.1
Pain all over the body in last month	0.9	1.0	6.4	-0.5	-0.8	-1.0	-1.5	0.4	0.7	-0.6	-1.2	-0.1	0.3	0.6	0.6	-2.5	1.0	0.3	-1.4	-0.4	0.6
Diabetes (self-reported)	1.3	2.0	7.7	0.4	-0.1	0.9	0.6	2.1	2.8	1.0	0.7	0.1	-2.4	-1.5	-2.2	1.2	-1.4	1.7	0.3	1.1	1.2
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.9	0.3	1.0	0.1	-1.4	-0.5	-0.6	0.2	0.1	0.7	0.7	1.1	0.7	-1.1	0.7	-0.4	0.0	0.1	-0.0
Medication: Ramipril	0.4	0.5	2.0	-0.7	-1.4	-0.9	0.6	0.6	0.5	-0.7	-0.8	-0.7	0.4	1.1	0.5	-0.2	0.8	-0.3	-1.0	-0.3	-0.1
Medication: Simvastatin	0.3	0.4	2.2	0.5	0.3	0.7	-0.1	1.0	0.3	0.5	0.3	0.5	0.0	-0.1	-0.1	0.1	-0.1	0.7	1.5	0.8	1.4
Fluid intelligence score	1.0	2.1	5.0	1.8	0.8	1.0	-0.8	0.0	2.2	2.2	0.6	1.6	-1.8	-0.4	-1.8	-1.9	-0.8	2.0	0.1	-0.3	2.2
Illnesses of siblings	0.1	0.1	0.4	-0.0	-0.5	0.1	0.5	-0.4	0.1	-0.0	0.4	0.2	0.1	-0.1	0.1	0.6	0.3	-0.6	0.0	0.0	-0.6
Neuroticism score	0.3	0.6	4.2	0.3	0.4	0.0	1.2	-1.2	-1.1	0.2	0.7	0.5	-0.5	-2.0	-0.5	0.3	-0.5	0.1	0.2	0.7	-0.5
Weight	1.9	9.5	18.0	3.4	2.5	4.0	-0.2	3.0	4.0	3.9	3.2	3.9	-3.5	0.3	-3.6	1.0	-2.2	4.2	2.2	1.7	3.8
Impedance of arm (right)	0.2	0.9	4.3	-0.1	-0.7	-0.6	1.1	-1.9	-2.1	-0.6	-0.0	-0.2	1.2	1.0	1.1	-0.3	0.5	-0.9	-0.5	0.3	-0.9
Arm fat percentage (right)	2.3	8.9	18.0	3.5	3.1	4.2	0.3	2.1	2.8	3.9	3.8	3.9	-3.2	1.1	-3.4	2.1	-2.4	3.5	2.5	2.2	2.8
Trunk fat-free mass	0.1	0.8	4.5	-0.0	-0.1	0.1	-1.4	1.3	2.1	0.1	-0.7	0.3	-0.7	0.2	-0.4	-1.5	0.1	0.8	-0.6	-0.3	1.0
Hip circumference	2.3	10.1	19.4	3.2	2.9	4.1	0.2	3.6	4.1	3.8	3.1	3.9	-3.6	-0.6	-3.6	0.7	-2.0	4.4	2.1	2.0	4.3
Time employed in main current job	7.1	8.2	14.3	3.1	1.6	3.6	1.4	3.4	2.8	3.8	3.0	2.7	-3.3	-1.5	-3.4	1.7	-2.2	3.8	3.2	1.6	3.4
Alcohol intake versus 10 years previously	1.4	2.1	4.5	1.8	1.1	1.5	0.7	1.1	1.4	2.0	1.6	2.0	-1.5	-0.8	-1.5	0.7	-1.1	2.1	1.1	1.4	1.5
Father’s age at death	0.9	1.3	3.9	1.6	0.2	1.7	2.0	0.6	-0.3	1.6	1.5	1.6	-0.9	0.7	-1.1	0.6	-0.5	-0.1	0.8	1.0	0.7
Worrier / anxious feelings	0.8	1.5	7.5	0.4	0.2	0.2	1.0	-0.1	0.7	1.3	1.0	0.6	-2.0	-2.7	-1.9	1.0	-2.1	1.2	0.4	0.2	-0.1
Frequency of tiredness / lethargy in last 2 weeks	2.4	3.9	11.0	-2.0	-0.4	-2.5	-1.0	-3.3	-1.9	-2.5	-2.2	-2.0	1.9	0.5	2.0	-1.6	0.9	-2.0	-2.5	-0.8	-2.5
Falls in the last year	1.0	1.3	3.8	0.8	0.1	0.6	-1.0	0.4	1.9	1.5	0.5	0.9	-1.7	-0.8	-1.6	-0.3	-1.2	1.9	0.1	-0.6	1.5
Hair/balding pattern: Pattern 3	0.3	0.4	1.9	-0.4	-0.5	-0.0	-1.2	-0.4	0.3	0.4	-0.3	-0.6	-0.5	-1.4	-0.4	-0.0	-0.6	0.2	-0.5	-1.4	0.2
Number of live births	0.6	0.8	1.9	-1.0	-1.2	-1.4	-0.4	0.4	0.1	-0.9	-1.3	-0.8	0.8	0.6	1.0	-1.2	1.0	-0.5	-1.2	-0.6	-0.7
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	8.1	-2.8	-1.0	-2.4	0.6	-1.4	-0.5	-2.4	-2.7	-2.8	1.3	-0.0	1.3	-0.8	0.4	-1.7	-2.0	-2.3	-2.1
Pulse rate	0.4	0.7	2.8	-0.5	1.7	-0.3	0.4	-0.7	-1.2	-0.9	-0.2	-0.5	1.3	0.5	1.2	0.3	1.1	-0.6	-0.2	-0.6	-0.6
Happiness	0.5	0.6	2.1	0.1	0.7	-0.6	0.3	-0.1	1.4	0.7	-0.3	0.0	-1.3	-0.9	-1.1	-0.5	-1.0	0.4	-0.8	-0.6	0.1
Noisy workplace	0.2	0.3	0.9	-0.5	-0.1	-0.1	-0.6	0.8	0.9	-0.4	-0.4	-0.5	-0.2	-0.9	-0.1	0.0	-0.1	-0.5	-1.0	0.1	-0.4
Qualifications: A levels/AS levels or equivalent	0.3	0.7	3.0	0.7	-1.0	0.6	0.1	0.9	1.7	0.5	0.3	0.4	-0.9	-0.7	-0.8	-0.6	0.1	0.7	0.7	1.3	1.4
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.2	-0.6	-0.5	0.0	-0.5	-0.2	0.5	-0.2	-0.3	-0.6	-0.9	-0.1	-0.8	0.3	-1.1	0.1	-0.9	-0.6	-0.5
Mouth/teeth dental problems: Dentures	2.0	3.3	8.8	2.5	3.0	2.9	-0.8	0.5	0.0	2.2	2.7	2.6	-1.0	-0.0	-1.3	1.5	-1.6	0.9	2.2	1.1	1.4
Asthma	1.0	2.0	8.1	1.4	-0.8	1.0	-1.5	-0.2	1.6	1.7	1.0	1.6	-1.8	-1.1	-1.6	-1.0	-1.1	2.9	-0.1	0.2	1.7
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	6.4	-1.3	0.3	-0.7	0.9	-2.0	-2.5	-1.7	-0.6	-1.3	1.8	1.0	1.6	1.0	0.6	-1.7	-0.2	-0.4	-1.7
Medication: Cholesterol lowering	1.0	1.5	4.1	1.2	1.1	1.6	-0.1	1.2	1.4	1.9	1.0	1.4	-1.0	-0.4	-1.1	0.1	-0.8	1.7	0.9	0.8	2.0
Depression (self-reported)	0.6	0.7	2.9	-0.7	0.3	-0.7	-1.7	-0.7	-0.2	-0.3	-0.9	-0.6	0.7	0.5	0.8	-1.3	0.4	-0.8	-1.1	-0.9	-0.6
Medication: Lansoprazole	1.7	1.9	5.4	1.9	0.2	1.9	-1.6	0.5	0.4	1.2	1.2	2.2	-0.0	-0.1	0.0	-1.2	0.8	2.0	1.1	1.9	2.3
Prospective memory result	1.6	2.0	6.9	1.7	-1.1	2.0	0.1	2.6	0.7	1.0	1.7	1.6	-0.4	0.0	-0.4	1.2	0.5	1.4	2.6	1.4	1.3
Lung cancer (father)	0.2	0.3	1.3	-0.2	-1.2	-0.6	-1.1	0.3	0.2	-0.4	-0.8	-0.7	-0.1	-0.1	0.1	-0.8	-0.2	-0.0	0.3	0.3	-0.2
Illnesses of mother	1.1	1.3	6.7	0.8	-0.5	0.8	-0.2	2.6	1.9	0.8	0.4	1.3	-0.0	-0.5	0.2	-0.9	1.2	1.4	0.2	0.6	2.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.0	3.1	8.2	-2.7	-0.9	-2.5	0.5	-1.5	-1.1	-2.4	-2.6	-2.9	1.5	0.1	1.6	-0.9	0.4	-1.6	-1.5	-1.5	-2.1
Pulse wave Arterial Stiffness index	0.6	0.7	2.8	1.0	1.1	0.5	-0.9	0.3	0.3	0.7	0.4	1.2	-0.2	-1.2	-0.2	-1.2	0.5	0.4	-0.2	1.0	1.7
Impedance of arm (left)	0.1	0.5	3.0	0.1	0.0	-0.3	1.4	-1.7	-1.6	-0.2	0.2	-0.1	0.7	0.5	0.6	0.0	0.1	-0.5	-0.3	0.0	-0.6
Arm fat mass (right)	2.3	9.6	18.7	3.6	3.1	4.3	-0.1	2.5	3.2	3.9	3.6	4.1	-3.3	0.7	-3.5	1.6	-2.3	4.0	2.5	2.1	3.4
Trunk predicted mass	0.1	0.8	4.5	-0.0	-0.2	0.1	-1.4	1.4	2.1	0.2	-0.7	0.3	-0.7	0.1	-0.4	-1.6	0.1	0.9	-0.6	-0.3	1.1
Standing height	0.1	0.9	4.9	0.4	-1.8	0.0	0.1	0.7	1.3	0.1	-0.5	0.5	-0.1	-0.3	0.1	-2.2	0.7	1.2	-0.6	-0.1	1.5
Length of working week for main job	1.0	1.1	4.3	0.8	2.1	0.2	0.5	-1.3	0.4	1.3	0.8	1.1	-1.1	-0.6	-1.3	0.2	-1.5	0.7	-0.4	-1.6	0.0
Exposure to tobacco smoke at home	0.3	0.4	1.2	-0.6	0.2	-0.6	0.8	-0.3	-0.1	-0.4	-0.4	-0.6	-0.5	-0.6	-0.4	0.3	-0.8	0.3	-0.8	-0.8	-1.1
Breastfed as a baby	1.1	1.3	4.8	1.5	0.2	1.2	1.2	0.8	-0.8	0.5	1.7	1.3	0.5	1.4	0.1	1.7	0.3	-0.2	2.2	1.5	0.3
Tense / ‘highly strung’	1.8	3.0	5.5	-2.2	-2.1	-2.0	0.6	-1.1	-2.2	-2.4	-1.8	-2.1	1.8	-1.0	2.0	-0.3	1.2	-2.0	-1.3	-0.1	-2.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	1.6	0.3	-0.0	0.1	0.4	-0.6	-0.8	-0.1	-0.1	0.3	1.3	-0.3	1.2	-0.9	0.9	-0.2	0.2	-0.4	-0.5
Hair/balding pattern: Pattern 4	0.1	0.3	1.3	0.2	0.0	0.1	0.1	-0.3	-0.8	-0.1	0.2	-0.2	0.3	1.1	0.2	1.0	-0.2	-0.5	-0.3	-0.3	-1.2
Birth weight of first child	0.5	0.8	1.8	-0.7	-0.8	-0.7	-1.1	-1.2	-0.5	-1.0	-0.8	-0.5	1.3	1.2	1.3	-1.1	1.3	-0.9	0.1	-0.2	-0.3
Peak expiratory flow (PEF)	1.7	3.9	8.9	-3.0	-0.9	-2.3	-0.7	-1.0	-0.4	-2.8	-2.8	-2.5	2.1	0.3	2.2	-1.8	1.4	-2.2	-2.3	-2.1	-1.7
Pulse wave reflection index	1.0	1.2	3.1	1.0	1.6	0.8	-0.2	1.0	0.4	1.0	1.1	1.3	-1.2	-1.4	-1.4	0.5	-0.8	0.5	1.1	1.8	1.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	3.4	0.3	-0.2	-0.0	-0.3	-0.0	1.2	0.7	-0.1	0.2	-1.3	-1.8	-1.1	-0.1	-1.4	0.7	-0.1	-0.7	-0.4
Loud music exposure frequency	0.6	0.7	4.5	1.0	2.1	1.0	-0.1	-0.4	-0.4	0.5	1.1	1.1	-0.1	0.2	-0.2	1.0	-0.2	0.3	1.3	0.3	0.1
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	4.6	-0.7	-1.9	-1.1	-0.9	0.4	2.1	-0.0	-1.5	-1.0	-0.9	-0.5	-0.5	-2.1	0.0	0.6	-1.3	-0.6	0.6
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	3.7	-0.2	0.1	-0.0	1.5	-1.1	-1.9	-0.6	0.7	-0.4	-0.3	0.8	-0.5	1.8	-0.8	-0.2	1.2	-0.2	-1.1
Blood clot in the leg (DVT)	1.3	1.7	4.5	-1.7	-1.3	-1.4	-0.9	0.1	-0.1	-1.3	-1.6	-2.1	0.5	1.7	0.6	-0.3	0.0	-2.1	-1.9	-0.5	-1.6
Medication: Paracetamol	1.5	2.4	7.5	2.6	2.7	1.6	-0.2	-0.6	-0.6	1.9	2.4	2.7	-0.2	1.0	-0.5	0.5	-0.3	1.7	1.4	1.2	1.4
Headache pain in last month	1.0	1.8	6.4	-0.9	1.2	-0.7	2.1	-2.0	-2.5	-1.6	-0.4	-1.1	1.8	-0.3	1.5	0.7	0.7	-1.5	-0.3	0.1	-1.4
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.5	-0.9	0.1	-0.7	-0.1	-0.1	-0.3	-0.8	-0.8	-0.4	0.3	-0.4	0.4	-0.6	0.4	-0.6	-1.2	-1.1	-0.6
Glaucoma (self-reported)	1.3	1.6	3.4	-1.4	-1.4	-1.1	-1.7	-1.1	-0.8	-1.2	-1.7	-1.0	1.3	0.4	1.4	-1.8	1.2	-0.9	-1.3	-0.9	-0.8
Gout (self-reported)	0.4	0.5	2.1	0.6	0.5	0.9	1.3	0.9	0.3	0.5	1.1	0.3	-0.3	0.1	-0.5	1.4	-0.7	-0.3	0.4	0.4	-0.0
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	3.7	-0.7	-1.9	0.6	-0.5	0.5	-0.0	-0.9	-0.3	-0.8	0.7	-0.0	0.6	0.1	0.7	0.4	0.3	1.1	0.3
Medication: Amlodipine	0.4	0.6	2.2	-0.6	-1.5	-0.8	0.9	0.9	0.1	-0.6	-0.4	-1.4	-0.2	0.5	-0.1	0.9	-0.4	-0.7	-0.1	0.2	-1.1
Medication: Ventolin 100micrograms inhaler	1.5	2.0	4.8	2.0	-0.6	1.9	0.8	0.6	0.7	1.6	2.2	1.7	-1.0	0.7	-1.2	1.9	-0.7	1.5	1.8	1.4	1.0
Birth weight	0.4	0.9	3.1	-0.9	0.2	-1.1	-1.4	-0.9	-0.0	-0.8	-1.2	-0.0	1.3	-0.1	1.4	-1.8	1.2	-0.1	-0.1	-0.6	-0.2
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.4	-1.0	0.2	-1.0	-0.2	-1.1	-0.9	-1.2	-0.9	-1.1	0.4	-0.2	0.4	-0.2	0.1	-1.6	-0.6	0.7	-0.8
High blood pressure (siblings)	0.3	0.4	1.1	-0.9	-0.7	-0.4	0.2	1.0	-0.1	-0.7	-1.0	-1.0	0.4	-0.6	0.4	-0.7	0.1	-0.2	-0.8	-0.0	0.3
Forced vital capacity (FVC), Best measure	1.0	3.7	9.6	-2.8	-1.5	-2.8	-0.1	-1.7	-1.0	-2.6	-2.8	-3.1	1.5	0.6	1.6	-1.1	0.4	-1.6	-2.0	-1.8	-2.2
Body fat percentage	4.0	15.8	30.7	4.8	3.6	5.5	0.8	3.0	3.6	5.2	4.9	5.2	-4.1	0.4	-4.4	2.3	-2.9	5.1	3.5	2.9	4.6
Leg fat percentage (right)	3.2	11.7	22.0	4.2	2.6	4.7	0.8	3.0	3.5	4.5	4.0	4.4	-3.4	-0.4	-3.6	1.5	-2.2	4.7	2.9	2.6	4.2
Arm fat-free mass (right)	0.4	1.8	7.3	0.9	0.6	1.3	-0.9	2.4	2.7	1.1	0.3	1.3	-1.4	0.2	-1.2	-0.8	-0.3	1.9	0.5	0.4	2.1
Exposure to tobacco smoke outside home	0.8	1.0	3.1	1.0	0.1	1.3	1.8	0.4	0.2	0.7	1.4	1.0	0.1	-1.1	0.0	1.5	0.2	1.2	1.5	1.0	0.8
Comparative body size at age 10	1.1	3.0	7.6	2.0	1.4	2.2	1.4	-0.7	0.2	1.8	2.7	2.1	-2.0	-0.2	-2.3	2.6	-2.0	0.9	2.1	0.1	0.2
Number of full brothers	0.3	0.3	1.6	-0.3	-0.7	-0.4	0.5	0.6	0.3	-0.4	-0.7	-0.5	0.1	-0.1	0.2	-0.4	-0.4	-0.4	-1.3	-0.7	-0.9
Worry too long after embarrassment	0.5	0.9	3.1	0.7	1.5	0.4	1.1	-1.8	-0.9	0.7	0.9	0.9	-0.3	-1.6	-0.5	0.4	-1.0	-0.4	-0.1	-0.8	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.5	-0.5	-1.2	-0.5	0.6	0.2	0.0	-0.3	-0.2	-0.6	-0.3	-0.8	-0.1	0.3	-0.3	-0.1	-0.7	-0.8	-1.2
Wheeze or whistling in the chest in last year	0.2	0.3	1.3	0.1	-0.8	0.3	-1.1	0.0	0.6	0.3	0.1	0.4	-0.7	0.5	-0.5	-0.5	-0.1	1.0	-0.6	0.7	0.4
Number of children fathered	0.5	0.5	1.4	0.7	0.7	0.4	0.4	-0.4	0.3	1.2	0.5	0.2	-0.7	-0.8	-0.9	-0.0	-0.8	0.9	1.1	-0.9	0.9
Reason for reducing amount of alcohol drunk: Health precaution	2.7	3.2	9.2	1.9	0.1	1.8	0.2	2.1	0.1	2.0	1.9	2.1	-1.1	-0.0	-1.2	0.5	-0.5	3.0	2.3	2.7	3.0
Age at first live birth	0.7	1.2	5.2	0.7	0.9	1.1	0.2	2.3	-0.2	0.5	0.8	0.2	-0.2	0.3	-0.5	1.2	0.4	0.7	1.9	1.8	2.0
Pulse wave peak to peak time	0.6	0.7	2.6	-1.0	-1.0	-0.5	1.0	-0.3	-0.2	-0.6	-0.4	-1.1	0.1	1.2	0.1	1.0	-0.6	-0.3	0.2	-1.0	-1.6
Health satisfaction	1.2	1.6	3.5	1.7	1.4	1.7	1.9	0.3	0.3	1.3	1.9	1.7	-1.2	-0.1	-1.4	1.5	-1.0	0.7	1.0	0.5	0.6
Shortness of breath walking on level ground	0.5	0.6	2.2	0.9	0.0	0.9	1.5	-0.6	-0.4	0.7	1.2	1.0	0.2	0.8	-0.0	1.4	-0.5	0.2	0.6	-0.7	-0.4
Qualifications: College or University degree	0.1	0.2	1.6	-0.2	-0.5	0.0	0.1	0.3	0.6	-0.3	-0.5	-0.4	0.1	1.3	0.1	-0.7	0.3	0.2	-0.3	0.2	0.1
Eye problems/disorders: None of the above	0.9	1.0	2.4	0.6	0.8	0.8	1.1	0.5	0.9	1.3	0.8	0.5	-1.5	-1.4	-1.5	1.2	-1.6	0.7	-0.2	-0.6	0.1
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.4	0.8	0.1	1.2	-0.4	0.8	0.6	1.0	1.1	0.7	-1.5	-0.6	-1.5	1.2	-1.4	1.1	0.3	-0.2	0.7
Emphysema/chronic bronchitis	1.6	1.8	4.8	1.0	0.1	0.2	-2.1	-1.0	1.7	1.6	-0.1	0.5	-1.3	-2.2	-1.2	-1.8	-1.5	1.0	-1.7	-1.4	0.5
Medication for pain relief, constipation, heartburn	1.2	2.0	6.6	-1.7	-2.6	-1.3	0.2	0.4	0.8	-0.8	-1.5	-2.1	-1.4	-1.6	-1.1	0.1	-1.2	-1.0	-1.5	-1.9	-1.6
Neck or shoulder pain in last month	1.6	2.2	5.3	-0.9	-0.7	-1.4	0.1	-1.9	-1.4	-1.4	-1.5	-1.5	2.2	1.0	2.3	-1.4	1.9	-1.2	-1.2	-1.7	-1.4
Medication: Blood pressure	0.4	0.6	3.5	0.3	-0.6	0.2	1.9	0.1	0.5	0.5	0.7	-0.1	-0.6	1.0	-0.7	1.7	-0.7	0.0	0.6	0.4	-0.6
Angina (self-reported)	0.6	0.8	2.8	-0.9	1.4	-0.6	-0.5	-1.1	-0.7	-0.8	-0.8	-0.6	0.7	1.3	0.6	0.0	-0.2	-1.7	-0.7	-0.6	-1.4
Migraine (self-reported)	1.2	1.5	3.1	-1.5	-0.3	-1.6	-0.1	-1.7	-0.5	-1.2	-1.4	-1.5	-0.8	-1.6	-0.6	-0.1	-1.2	-0.7	-1.8	-1.5	-1.8
Medication: Ibuprofen	0.7	0.8	4.4	-0.1	1.0	-0.0	0.1	-1.6	-2.1	-0.8	0.3	-0.0	1.3	0.6	1.0	0.8	0.4	-0.6	0.3	-0.2	-1.0
Medication: Allopurinol	0.8	1.1	3.6	0.9	0.2	0.4	1.2	0.9	1.9	1.5	0.7	0.5	-1.6	-0.3	-1.6	0.6	-1.4	1.0	-0.2	0.1	0.9
Medication: Omeprazole	0.4	0.5	2.2	0.2	-0.4	0.0	-0.0	-0.1	-0.5	-0.4	0.4	0.3	1.3	0.2	1.3	-0.3	1.5	0.2	0.7	1.0	0.0
Medication: Seretide 50 evohaler	2.2	2.5	7.1	1.8	-1.2	1.3	-2.0	1.1	2.7	1.6	0.9	1.7	-1.5	-1.2	-1.4	-1.0	-0.6	2.2	0.1	1.4	2.5
Mean time to correctly identify matches	1.0	2.0	3.9	1.4	-0.7	1.5	-0.0	1.1	1.5	1.8	1.7	1.4	-2.0	0.8	-1.9	1.5	-1.6	1.9	0.9	0.9	0.7
Heart disease (mother)	0.9	1.1	5.7	-0.4	0.2	-0.4	0.5	-2.4	-1.8	-0.7	-0.1	-0.8	0.7	1.2	0.4	1.0	-0.7	-1.1	0.3	-1.2	-1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.1	1.3	0.9	0.7	0.4	-0.0	0.5	0.9	1.1	1.5	0.3	-0.6	0.1	-0.2	0.7	0.8	1.2	0.9	1.1
Whole body fat mass	3.3	13.7	25.2	4.3	3.1	5.0	0.3	3.2	3.9	4.8	4.2	4.7	-4.0	0.3	-4.2	1.8	-2.7	5.0	3.0	2.4	4.5
Leg fat mass (right)	2.8	11.0	20.3	4.0	2.9	4.5	0.4	3.0	3.5	4.3	3.8	4.4	-3.3	0.2	-3.5	1.4	-2.1	4.4	2.9	2.4	4.0
Arm predicted mass (right)	0.4	2.1	6.9	1.3	0.9	1.7	-0.6	2.4	2.6	1.3	0.8	1.6	-1.4	0.3	-1.4	-0.4	-0.4	2.0	1.0	0.7	2.2
Pulse rate, automated reading	0.2	0.6	5.0	-0.5	2.2	-0.6	-0.9	-0.9	-0.2	-0.3	-0.2	-0.4	0.6	0.8	0.6	0.2	0.1	0.1	-0.5	-0.9	-0.5
Alcohol intake frequency.	0.1	0.3	1.4	-0.2	1.2	-0.1	0.7	-1.1	-0.4	0.1	-0.1	-0.0	-0.2	-0.7	-0.3	0.0	-0.1	0.2	-0.5	-0.4	0.3
Comparative height size at age 10	0.1	0.7	5.6	-0.5	-2.4	-0.1	-1.2	0.0	0.8	-0.5	-0.6	-0.8	-0.4	1.4	-0.3	-0.6	-0.6	0.2	-0.2	-0.1	-0.2
Number of full sisters	0.7	0.8	2.2	1.0	1.2	0.4	-0.2	0.9	1.1	0.6	0.5	1.5	-0.1	0.2	-0.1	-1.0	0.6	1.3	0.8	1.2	1.4
Suffer from ‘nerves’	0.4	0.6	3.1	0.4	-0.2	-0.6	-0.0	-0.6	0.7	1.1	-0.3	0.6	-0.8	-1.4	-0.5	-1.8	-0.5	0.7	-0.8	-0.0	0.1
Overall health rating	0.7	1.4	3.7	-1.6	-1.3	-1.9	0.2	-0.6	-0.3	-1.5	-1.7	-1.6	0.5	0.2	0.7	-1.2	0.5	-1.3	-1.8	-0.3	-1.2
Chest pain or discomfort	0.6	0.8	3.5	-1.3	-1.2	-1.1	-0.6	-0.5	-0.1	-0.7	-1.1	-1.0	0.3	-0.3	0.5	-0.8	0.0	-0.5	-1.9	-1.1	-1.1
Had major operations	0.5	0.6	3.4	0.5	0.6	1.1	1.3	1.9	0.5	0.4	0.9	-0.0	-0.6	0.6	-0.6	1.1	-0.2	-0.3	0.7	0.4	0.4
Age at last live birth	0.1	0.2	0.6	0.0	0.6	0.1	0.5	0.8	-0.5	-0.0	-0.0	-0.2	0.1	-0.0	-0.1	0.5	0.4	0.2	0.5	0.2	0.8
Family relationship satisfaction	4.1	5.1	13.8	1.7	0.8	1.9	1.6	1.9	3.4	2.8	1.7	1.5	-3.7	-2.7	-3.6	1.3	-3.1	2.6	0.2	-0.5	1.2
Leg pain on walking	0.2	0.2	0.6	0.3	0.8	-0.3	0.6	-0.7	0.6	0.4	-0.1	0.6	-0.4	0.1	-0.4	-0.6	-0.2	0.4	-0.4	-0.5	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	3.1	-1.2	-0.3	-1.8	0.8	-0.8	0.1	-0.4	-1.2	-1.7	-0.3	0.1	-0.3	0.5	-0.8	-1.4	-0.7	-1.5	-1.2
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.3	-0.9	0.3	-0.9	0.4	-0.7	-0.3	-0.5	-0.5	-1.4	-0.0	-0.4	-0.1	0.8	-0.9	-0.5	-0.6	-1.5	-1.3
Illness, injury, bereavement, stress in last 2 years	0.9	1.2	6.8	0.6	-0.2	-0.1	-0.9	0.9	0.8	0.4	-0.4	1.3	1.0	-0.1	1.1	-2.6	2.0	0.0	-0.1	-0.2	1.8
Medication: Aspirin	3.2	4.2	10.8	2.5	1.7	2.9	1.4	2.3	0.6	2.0	2.7	2.5	-0.6	1.3	-0.9	2.0	-0.3	1.3	3.3	2.9	2.1
Supplements: Vitamin C	0.4	0.5	1.9	0.6	-1.4	0.2	-0.6	0.9	1.1	0.5	0.3	0.5	-0.4	1.3	-0.3	-0.6	0.0	-0.1	0.0	1.1	0.7
Knee pain experienced in last month	0.5	0.8	3.0	0.2	1.7	0.3	-1.0	0.5	1.4	0.7	-0.2	0.8	0.2	1.7	0.3	-1.4	0.5	1.0	0.0	0.4	0.8
Hypertension (Self-reported)	0.2	0.7	2.8	0.6	0.1	0.4	1.4	0.7	0.1	0.3	0.8	0.1	0.1	1.6	-0.1	1.6	0.0	0.2	1.7	0.7	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	5.5	0.9	0.2	0.8	0.2	0.1	1.2	1.1	0.5	1.0	-0.6	-1.0	-0.3	-0.3	0.0	2.3	-0.4	-0.3	0.8
Illnesses of father: Heart disease	1.5	2.1	6.3	-0.9	0.8	-0.8	0.5	-1.3	-2.5	-2.1	-0.5	-0.7	2.5	1.4	2.2	0.2	1.9	-2.3	-0.4	-0.2	-0.6
Illnesses of siblings: Diabetes	0.7	0.8	2.8	0.8	0.2	0.6	-0.5	0.8	1.7	0.9	0.6	1.0	-1.4	-1.1	-1.2	-0.5	-0.9	0.9	-0.2	0.6	0.7
Smoking status: Previous	0.2	0.3	1.8	-0.1	1.3	0.4	0.7	-0.0	0.1	-0.0	0.5	0.4	0.2	0.4	0.1	1.0	-0.0	0.3	0.8	-0.4	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	1.8	-0.2	-0.2	-0.1	0.5	0.4	0.2	-0.4	-0.6	0.2	0.1	0.3	0.2	-1.3	0.4	0.5	-0.5	0.9	0.7
Whole body fat-free mass	0.2	1.1	6.5	0.4	0.6	0.7	-1.4	1.5	2.5	0.7	-0.2	0.8	-1.2	0.4	-1.0	-1.1	-0.3	1.3	-0.1	-0.1	1.4
Leg fat-free mass (right)	0.3	1.5	7.1	0.6	1.1	1.1	-1.5	1.4	2.7	1.0	0.3	1.1	-1.5	0.9	-1.4	-0.4	-0.8	1.6	0.2	0.0	1.4
Arm fat percentage (left)	2.3	9.1	17.8	3.5	3.3	4.2	0.6	2.1	2.9	3.9	3.7	3.8	-3.3	1.0	-3.6	2.3	-2.6	3.6	2.5	1.9	2.8
Average weekly red wine intake	0.5	0.7	2.9	0.1	-0.2	0.8	-1.0	1.7	1.7	0.7	-0.1	0.0	-0.8	-0.4	-0.7	-0.4	-0.3	1.0	-0.1	0.4	1.4
Handedness (chirality/laterality): Left-handed	0.7	0.8	4.2	-1.2	0.4	-1.3	0.1	-0.9	0.9	-0.2	-1.1	-0.5	-0.1	-0.9	0.3	-1.0	0.0	0.9	-2.0	-1.2	-0.6
Mood swings	0.1	0.2	1.4	-0.3	-0.6	-0.0	0.7	0.2	0.1	0.0	0.0	-0.6	-0.4	0.0	-0.4	0.8	-0.4	0.2	0.5	1.2	-0.2
Loneliness, isolation	0.4	0.6	1.5	-1.1	-0.9	-0.9	1.2	-0.0	-0.6	-1.1	-0.8	-1.1	0.3	-0.4	0.4	0.1	0.3	-0.8	-0.8	0.8	-0.7
Long-standing illness, disability or infirmity	0.4	0.6	2.6	-1.0	-1.0	-0.6	-1.3	0.3	0.3	-0.9	-1.1	-0.7	0.4	0.3	0.7	-1.6	0.8	0.2	-0.7	0.3	0.3
Ever had bowel cancer screening	1.0	1.2	5.8	-1.2	-0.7	-1.4	-2.4	-0.5	0.4	-0.5	-1.3	-1.1	-0.1	-1.0	0.1	-0.9	-0.7	-0.8	-1.7	-0.9	-0.8
Diabetes diagnosed by doctor	0.9	1.5	4.6	0.7	-0.0	0.9	0.4	2.1	1.9	0.8	0.9	0.6	-1.8	-0.7	-1.7	1.0	-0.8	1.2	0.5	1.8	1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.3	1.2	-0.3	1.3	0.5	0.1	-0.8	0.5	1.5	1.1	-0.6	0.4	-0.6	1.1	-0.2	0.5	1.0	1.3	0.4
Friendships satisfaction	0.9	1.1	2.7	-0.7	-0.9	-1.1	1.2	-0.3	1.0	-0.3	-0.8	-0.9	-1.4	-1.5	-1.3	-0.0	-1.5	-0.5	-1.7	-0.8	-1.1
Qualifications: nursing, teaching	0.9	1.4	3.5	-1.3	-0.6	-1.4	-1.4	-0.5	0.3	-0.8	-1.7	-1.6	-0.4	1.5	-0.2	-1.2	-0.4	-1.6	-1.9	-0.7	-1.3
Commuting to job workplace: Walk	1.0	1.1	3.9	1.0	2.0	0.9	-0.1	0.2	0.9	1.4	0.8	0.8	-1.4	-1.3	-1.5	0.1	-1.3	1.0	0.1	-0.6	0.4
Eye problems/disorders: Cataract	0.6	0.7	1.7	-0.3	-0.8	-0.4	0.9	-1.1	-1.2	-1.2	-0.1	-0.5	1.3	0.8	1.2	0.7	0.8	-0.8	0.8	0.0	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	4.1	-1.2	0.9	-0.9	-0.4	-1.6	-1.5	-1.4	-0.8	-1.3	1.7	0.6	1.6	0.3	0.2	-2.0	-0.0	-0.4	-2.0
Medication for cholesterol	0.3	0.4	1.6	0.5	1.2	0.3	0.5	0.8	0.6	1.0	0.3	0.9	-0.1	0.1	-0.1	-0.9	0.4	0.3	-0.4	0.2	1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	1.6	-0.1	1.3	-0.1	-0.0	-0.1	-0.2	-0.0	-0.0	0.2	0.2	0.1	0.2	0.1	0.2	0.0	-0.6	-0.0	-0.1
Back pain experienced in last month	0.1	0.2	0.6	-0.4	0.2	0.1	-0.5	-0.3	0.5	0.5	-0.2	-0.6	-0.3	0.2	-0.2	0.4	-0.8	0.2	-0.4	-0.6	-0.6
Mineral and other dietary supplements	0.7	0.9	2.7	0.7	0.9	0.9	-1.1	-0.7	-0.0	1.1	1.0	0.6	-1.2	-0.9	-1.3	1.0	-1.6	1.0	-0.4	-1.0	-0.3
Breast cancer (self-reported)	0.5	0.6	4.2	0.1	-0.9	0.5	0.3	1.0	1.3	0.6	-0.3	-0.2	-0.5	-2.0	-0.3	-0.7	-0.4	0.4	-0.5	-0.3	0.4
Asthma (self-reported)	1.3	2.5	10.2	1.5	-0.5	1.0	-2.1	-0.5	1.7	1.9	1.0	1.8	-2.1	-1.4	-1.9	-1.2	-1.3	3.2	-0.1	0.2	1.8
Osteoporosis (self-reported)	0.7	0.9	4.7	-1.2	-2.2	-0.9	-1.4	0.5	0.3	-0.8	-1.3	-1.2	0.6	-0.4	0.7	-0.9	0.5	-0.5	-0.2	-0.4	-0.3
Osteoarthritis (self-reported)	0.8	1.0	3.6	0.4	-0.8	0.3	-0.9	1.1	1.9	0.8	-0.3	0.8	-0.4	0.8	-0.2	-1.7	0.7	1.3	0.3	1.2	1.9
Medication: Aspirin	2.1	2.8	8.1	2.0	1.1	2.3	1.5	1.7	0.1	1.6	2.3	1.8	-0.6	1.0	-0.9	2.1	-0.5	0.7	2.9	2.4	1.4
Medication: Gliclazide	0.7	0.8	2.7	0.6	0.3	1.3	-0.8	1.6	0.7	0.6	0.7	0.9	-0.3	0.9	-0.3	0.2	0.2	1.1	0.8	1.4	1.5
Illnesses of father: None of the above (group 1)	1.3	1.6	4.0	1.1	-0.2	1.4	0.2	1.4	2.0	1.7	1.0	1.3	-1.6	-1.5	-1.5	0.3	-1.1	2.0	0.5	0.4	1.0
Smoking status: Current	0.4	0.7	2.1	1.4	0.4	1.0	0.5	0.8	-0.5	0.8	1.3	1.4	-0.5	0.4	-0.6	0.4	-0.1	0.3	0.3	1.2	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	6.5	-2.4	0.4	-1.6	0.7	0.2	0.0	-1.4	-1.7	-2.5	0.3	0.2	0.3	0.8	-1.0	-1.7	-0.8	-1.2	-2.0
Whole body water mass	0.2	1.0	6.1	0.3	0.5	0.6	-1.4	1.5	2.5	0.6	-0.2	0.7	-1.1	0.5	-1.0	-1.0	-0.3	1.2	-0.2	-0.1	1.3
Leg predicted mass (right)	0.3	1.4	6.5	0.7	1.1	1.1	-1.4	1.4	2.5	1.0	0.4	1.1	-1.5	1.0	-1.4	-0.3	-0.8	1.5	0.2	0.1	1.3
Arm fat mass (left)	2.3	9.4	18.2	3.5	3.0	4.3	0.1	2.6	3.3	3.9	3.5	4.0	-3.3	0.8	-3.5	1.7	-2.3	3.9	2.4	1.9	3.3
Number of self-reported non-cancer illnesses	0.7	1.1	4.0	-1.2	-0.9	-1.0	-2.0	-0.3	-0.5	-1.2	-1.4	-1.2	1.0	0.9	1.1	-1.5	1.0	-0.8	-0.9	0.5	-0.1
Average weekly champagne plus white wine intake	0.9	1.3	3.7	0.7	0.1	0.5	-0.1	-0.0	1.8	1.3	1.1	1.0	-1.8	-1.7	-1.8	0.8	-1.9	0.7	0.4	-0.7	0.6
Miserableness	0.2	0.4	2.6	-0.7	-0.0	-0.3	-0.1	-0.0	-0.9	-0.6	-0.5	-0.7	0.5	-0.5	0.5	-0.3	0.6	-0.5	-0.3	1.6	-0.2
Guilty feelings	0.5	0.7	4.3	0.4	0.3	-0.4	-0.2	-2.1	0.3	0.8	0.2	0.3	-0.9	-0.9	-0.8	-0.5	-1.1	-0.1	-0.6	-1.6	-0.8
Wears glasses or contact lenses	2.3	2.6	7.8	1.8	0.1	1.5	-2.7	1.6	0.6	1.3	1.1	1.6	0.1	-0.4	0.2	-1.5	1.0	1.8	2.2	2.8	2.6
Ever taken oral contraceptive pill	0.8	0.9	3.3	1.1	1.8	0.7	0.5	-1.0	-0.4	1.2	1.4	1.4	-0.7	0.5	-0.9	1.1	-1.1	0.8	-0.2	0.1	0.1
Hearing aid user	1.7	1.9	6.2	-1.2	-2.4	-1.2	-2.0	1.2	1.2	-0.6	-2.1	-1.4	0.5	-0.0	0.9	-2.5	0.5	-0.4	-1.6	-0.7	-0.0
Mother’s age at death	0.5	0.6	3.1	0.5	-0.9	0.1	-1.8	-0.9	0.4	0.1	-0.2	0.6	0.4	-0.2	0.6	-1.6	0.4	0.4	-0.9	-0.8	-0.2
Financial situation satisfaction	1.2	1.5	3.7	1.8	1.0	1.5	0.7	-0.2	-0.4	1.4	1.9	1.6	-0.4	0.4	-0.7	1.4	-0.5	0.6	1.9	1.7	1.1
Tinnitus: Yes, now most or all of the time	0.7	0.8	3.8	-0.9	-0.5	-0.4	0.0	-1.0	-1.0	-0.8	-0.1	-1.1	0.2	-1.5	0.2	0.9	-0.6	-1.1	-0.2	-0.5	-2.0
Commuting to job workplace: Public transport	1.6	2.0	4.4	1.8	0.4	1.5	-1.1	1.6	2.1	1.9	1.2	1.7	-1.5	0.0	-1.6	-0.3	-0.9	0.9	0.9	1.5	2.0
Eye problems/disorders: Glaucoma	0.4	0.4	2.0	-0.8	-0.0	-0.5	-0.8	0.1	-0.3	-0.5	-1.0	-0.4	0.6	0.1	0.6	-1.4	1.1	0.2	-0.1	0.2	0.9
Medication: Blood pressure	0.3	0.7	2.1	1.1	0.5	0.9	0.0	0.3	-0.6	-0.1	0.9	0.9	0.8	1.4	0.6	0.3	1.0	0.4	1.4	1.1	0.4
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.2	-0.9	1.0	-1.0	-1.3	-0.4	0.3	-0.5	-1.2	-0.8	0.5	-0.1	0.6	-1.5	0.8	-0.5	-0.2	0.4	0.2
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.1	-0.0	-0.4	-0.3	1.0	0.9	0.4	-0.5	-0.3	0.3	1.1	0.4	1.1	-0.8	1.8	-0.6	0.8	1.6	1.1
High cholesterol (Self-reported)	0.1	0.2	0.6	0.4	-0.5	0.6	-0.5	0.3	0.3	0.3	-0.1	0.3	0.1	0.0	0.1	-0.6	0.0	0.8	0.5	0.3	0.8
Medication: Bendroflumethiazide	0.1	0.1	0.6	-0.1	-0.5	0.2	-0.8	0.2	0.3	-0.4	-0.2	-0.1	0.2	0.6	0.2	0.0	0.3	0.6	0.6	0.3	0.1
Medication: Paracetamol	2.3	3.5	10.4	3.2	2.6	2.2	-0.7	-0.1	0.1	2.4	2.9	3.2	-0.7	0.4	-1.0	0.6	-0.4	2.2	2.0	1.4	1.8
Medication: Lisinopril	0.8	1.0	3.1	1.1	-0.1	0.6	1.5	-1.3	-1.8	-0.3	1.3	0.3	0.5	1.2	0.2	1.5	0.3	-0.5	1.3	0.5	-1.0
Medication: Atorvastatin	1.3	1.6	5.2	1.5	0.5	1.6	-0.1	1.4	1.3	1.3	1.6	1.4	-1.3	-0.0	-1.4	1.2	-0.8	1.1	0.8	2.3	1.4
Illnesses of father: High blood pressure	3.8	4.7	12.0	-3.3	-2.6	-2.5	1.0	-1.0	-2.0	-3.5	-2.5	-3.4	1.9	0.1	2.1	0.1	1.7	-2.5	-1.2	-0.0	-2.6
Alcohol drinker status: Never	0.7	0.8	4.4	-0.0	-1.7	-0.3	0.3	0.3	0.8	0.8	-0.1	-0.3	-1.2	-2.1	-1.0	-0.2	-1.0	0.8	-0.6	-0.9	0.2
Ever smoked	1.0	1.7	3.6	1.8	1.6	1.6	0.1	0.6	0.9	1.9	1.7	1.8	-1.2	-0.1	-1.4	0.6	-1.0	1.7	1.1	0.3	1.3
Basal metabolic rate	0.4	2.0	8.0	1.1	1.1	1.5	-1.1	1.8	2.8	1.4	0.7	1.5	-1.7	0.4	-1.6	-0.5	-0.8	2.0	0.4	0.3	1.9
Leg fat percentage (left)	3.5	12.8	25.7	4.3	2.8	5.1	0.7	3.2	3.4	4.6	4.3	4.7	-3.6	-0.3	-3.8	1.9	-2.5	4.7	3.0	2.7	4.4
Arm fat-free mass (left)	0.4	2.2	7.1	1.4	0.5	1.8	-0.8	2.4	2.7	1.5	0.9	1.7	-1.5	0.2	-1.4	-0.3	-0.5	2.0	0.9	0.9	2.2
Number of operations (self-reported)	0.7	1.0	3.4	-0.6	-1.9	-0.6	1.5	0.9	-0.4	-0.7	-0.7	-1.4	-0.2	0.5	-0.1	0.5	-0.3	-1.4	-0.9	-1.1	-1.5
Average weekly beer plus cider intake	0.3	0.4	1.8	0.9	0.1	0.8	0.5	-0.6	0.7	1.4	0.6	1.0	-0.5	-0.2	-0.6	-0.0	-0.4	1.0	-0.1	-0.6	0.3
Irritability	0.1	0.2	1.5	0.2	-1.2	-0.1	0.1	-0.2	-0.2	-0.1	0.1	0.2	0.1	-0.7	0.2	-0.8	0.5	0.1	0.2	0.5	-0.1
Risk taking	2.3	3.3	11.1	-1.8	-2.8	-1.4	0.2	-1.2	-2.2	-2.4	-1.5	-2.6	1.4	1.1	1.4	0.7	0.7	-3.3	-0.8	-0.1	-2.7
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.1	-0.5	-1.3	-0.9	-1.3	-0.3	-0.0	-0.6	-0.9	-0.5	1.2	0.1	1.1	-1.5	1.4	-0.7	0.2	1.1	0.8
Fractured/broken bones in last 5 years	0.4	0.5	2.9	0.3	0.6	0.7	0.2	1.7	0.9	0.4	0.3	0.1	-0.8	0.3	-0.9	0.7	-1.0	0.1	0.1	0.3	0.3
Age started oral contraceptive pill	0.7	0.8	2.7	1.4	0.6	0.8	0.1	1.6	0.9	1.3	1.0	1.1	-0.6	0.3	-0.7	0.1	-0.8	0.5	0.7	0.5	1.4
Diastolic blood pressure, automated reading	0.2	0.7	2.6	-0.3	0.7	0.2	-0.2	-0.6	-1.6	-0.7	0.5	-0.1	1.3	1.0	1.0	0.9	1.0	-0.7	1.2	1.2	-0.1
Ever depressed for a whole week	0.5	0.7	2.0	0.2	0.9	0.6	1.4	0.4	0.2	0.3	0.8	0.5	-1.1	-0.5	-1.2	1.2	-1.3	0.0	1.1	0.3	-0.1
Unable to work because of sickness or disability	1.3	1.7	4.7	1.5	2.2	1.7	0.2	0.9	0.2	1.5	1.9	2.0	-0.8	0.3	-1.1	1.0	-0.7	1.0	1.6	1.1	1.5
Commuting to job workplace: Cycle	0.3	0.4	2.0	0.3	-1.1	0.4	0.7	1.4	0.0	-0.3	0.1	0.5	-0.2	1.3	-0.1	0.1	0.3	-0.6	-0.3	0.9	0.1
Myopia	0.8	1.2	4.5	0.2	0.2	0.6	-0.3	1.1	1.5	1.5	0.2	0.4	-1.7	-1.0	-1.6	0.1	-1.2	2.1	0.2	-0.0	1.4
Vascular/heart problems diagnosed by doctor	0.2	0.6	3.4	-0.6	-0.0	-0.5	-1.1	-1.1	-0.4	-0.2	-0.7	-0.0	-0.4	-1.8	-0.2	-1.2	-0.3	0.0	-1.2	-1.1	-0.2
Cholesterol lowering medication	0.7	1.1	3.4	1.2	-0.6	1.1	-0.3	1.5	1.0	0.6	0.7	1.0	-0.3	-0.3	-0.4	-0.1	0.0	1.4	1.8	1.4	1.9
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.0	0.2	0.1	-0.3	-1.0	-0.5	-0.4	-0.5	0.0	0.3	1.2	-0.3	1.4	-1.3	1.4	0.2	0.4	1.2	0.3
Pain experienced in last month	0.5	0.8	2.7	0.6	-0.6	0.8	-0.2	0.6	0.9	0.9	0.8	0.7	-1.6	-0.8	-1.7	1.2	-1.5	0.5	0.2	-0.3	0.5
Supplements: Calcium	1.7	1.9	4.1	1.4	-0.1	1.7	1.7	1.9	1.3	1.6	1.5	1.4	-1.0	-0.3	-1.1	1.0	-0.2	1.7	1.8	0.5	2.0
Basal cell carcinoma (self-reported)	0.5	0.6	1.9	0.1	-1.3	-0.4	-0.9	0.5	1.1	-0.2	-0.5	-0.2	-0.4	-1.4	-0.2	-1.1	0.2	-0.9	-1.4	-0.1	-0.2
Heart attack/myocardial infarction (self-reported)	0.3	0.3	2.3	0.1	1.5	-0.4	0.5	-0.3	-0.5	0.1	-0.1	-0.1	0.3	1.2	0.3	-0.4	-0.0	-0.7	-0.2	-0.5	-0.5
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	4.5	-1.7	-1.3	-1.4	-1.0	0.3	0.2	-1.2	-1.6	-2.1	0.3	1.6	0.4	-0.4	-0.1	-2.1	-2.0	-0.7	-1.6
Heart disease (siblings)	1.4	1.7	8.6	-1.4	0.0	-1.6	-2.9	-0.6	-0.5	-1.4	-1.9	-1.4	1.2	0.5	1.3	-1.8	0.6	-0.8	-1.0	-1.0	-0.2
Alcohol drinker status: Previous	1.4	1.6	5.9	0.4	1.4	0.7	0.1	0.0	1.1	1.4	0.8	0.5	-2.3	-1.2	-2.4	1.1	-2.2	1.6	-0.3	-0.6	0.8
Pack years of smoking	0.6	1.0	3.0	1.0	0.6	0.6	-1.6	0.2	1.7	1.4	0.6	1.3	-1.1	0.8	-1.1	-0.5	-0.8	1.0	-0.1	-0.1	1.0
Impedance of whole body	0.2	1.1	5.5	1.4	-0.1	0.9	2.3	-1.1	-1.7	0.8	1.4	1.2	0.4	-0.6	0.1	0.3	-0.0	0.5	0.8	1.0	0.5
Leg fat mass (left)	3.1	12.1	23.5	4.2	3.1	4.8	0.5	3.1	3.4	4.4	4.1	4.7	-3.5	0.2	-3.8	1.7	-2.3	4.5	3.0	2.4	4.2
Arm predicted mass (left)	0.4	2.2	6.2	1.4	0.7	1.8	-1.2	2.2	2.5	1.4	0.8	1.8	-1.3	0.2	-1.3	-0.6	-0.3	2.0	0.9	0.9	2.3