Hub : Genes

SAP30L

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Cells Transformed fibroblasts 0.1820 0.0520 1.0e-04 0.137 NA 0.135 NA 0.152 1.9e-10 NA 2.6e-10 NA 1.8e-11
2 GTEx Esophagus Mucosa 0.2160 0.0710 9.7e-03 0.045 NA 0.060 NA 0.063 5.5e-04 NA 7.9e-05 NA 4.7e-05
3 GTEx Lung 0.2087 0.0623 2.6e-04 0.127 NA 0.102 NA 0.118 6.3e-10 NA 3.2e-08 NA 2.8e-09
4 GTEx Nerve Tibial 0.2411 0.0680 6.7e-04 0.061 NA 0.076 NA 0.081 3.7e-05 NA 4.6e-06 NA 2.3e-06
5 GTEx Pancreas 0.1330 0.0590 8.0e-03 0.022 NA 0.025 NA 0.021 4.1e-02 NA 3.0e-02 NA 4.2e-02
6 GTEx Skin Not Sun Exposed Suprapubic 0.2260 0.0720 4.1e-03 0.111 NA 0.070 NA 0.081 1.1e-06 NA 1.1e-04 NA 3.3e-05
7 METSIM Adipose 0.1530 0.0387 9.1e-06 0.042 0.035 0.043 0.044 0.036 5.6e-07 4.2e-06 4.1e-07 3.6e-07 3.4e-06
8 ROSMAP Brain Pre-frontal Cortex 0.0783 0.0311 5.8e-03 0.040 0.016 0.034 0.020 0.029 6.6e-06 3.6e-03 3.1e-05 1.1e-03 1.1e-04
9 TCGA Breast Invasive Carcinoma 0.0861 0.0231 1.3e-11 0.081 0.061 0.080 NA 0.079 3.5e-16 1.6e-12 5.2e-16 NA 9.1e-16
10 TCGA Colon Adenocarcinoma 0.1090 0.0450 2.5e-03 0.089 0.044 0.068 NA 0.089 8.3e-06 1.4e-03 8.5e-05 NA 8.2e-06
11 TCGA Head and Neck Squamous Cell Carcinoma 0.0838 0.0303 1.4e-04 0.059 0.033 0.045 NA 0.058 2.9e-07 1.1e-04 8.2e-06 NA 3.9e-07
12 TCGA Kidney Renal Clear Cell Carcinoma 0.1593 0.0472 4.9e-08 0.039 0.060 0.054 NA 0.057 2.9e-05 2.7e-07 9.8e-07 NA 4.6e-07
13 TCGA Lung Squamous Cell Carcinoma 0.0742 0.0302 9.6e-04 0.046 0.020 0.038 NA 0.043 4.9e-06 2.2e-03 3.5e-05 NA 9.8e-06
14 TCGA Prostate Adenocarcinoma 0.1113 0.0323 5.3e-07 0.062 0.052 0.061 NA 0.067 4.1e-07 3.6e-06 5.3e-07 NA 1.6e-07
15 TCGA Thyroid Carcinoma 0.2690 0.0660 4.3e-13 0.152 0.156 0.182 NA 0.175 1.4e-14 5.0e-15 2.1e-17 NA 8.1e-17

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 1.3 2.0 9.8 -0.9 -0.2 -1.3 -1.0 -1.2 -1.5 -1.0 3.1 -1.2 -1.2 -1.5 -1.2 -1.4 -1.4 -1.2
Bipolar Disorder or Schizophrenia 1.2 2.9 15.1 -1.3 -0.2 -1.8 -1.3 -3.9 -1.8 -1.0 2.5 -0.6 -1.2 -1.5 -1.0 -1.4 -1.3 -1.5
Depressed Affect (Nagel 2018) 0.9 1.8 3.6 1.2 1.0 1.3 0.8 -0.6 1.4 1.0 -1.9 1.6 1.5 1.5 1.9 1.5 1.1 1.2
Depression (Nagel 2018) 0.2 0.2 2.9 -0.2 -0.2 -0.3 -0.3 -1.7 -0.1 -0.3 0.3 0.2 -0.2 -0.1 -0.2 -0.2 -0.4 0.2
Intelligence (Savage-Jansen 2018) 0.3 0.8 2.3 1.0 0.8 0.6 1.1 -0.8 0.3 0.9 -1.1 0.9 0.6 0.4 1.4 0.4 0.4 1.5
Neuroticism (Nagel 2018) 0.9 2.2 3.3 1.3 1.0 1.3 1.0 -1.5 1.7 1.1 -1.5 1.8 1.7 1.7 1.8 1.7 1.2 1.5
Schizophrenia (2018) 0.8 1.6 16.4 -0.9 -0.1 -1.2 -0.9 -4.1 -1.0 -0.5 0.8 0.2 -0.5 -0.8 -0.1 -0.6 -0.5 -0.9
Schizophrenia vs Biploar Disorder 1.4 1.9 8.5 0.6 0.1 1.0 0.6 -0.1 1.6 1.3 -2.9 1.6 1.2 1.5 0.4 1.5 1.8 1.1
Worry (Nagel 2018) 0.5 1.2 2.6 0.8 1.1 0.6 0.9 -1.4 1.0 0.9 -0.4 1.1 1.2 1.0 1.6 1.0 1.0 1.3
Alzheimer’s Disease (in mother) 1.1 1.3 2.7 1.3 0.5 0.9 1.5 -0.5 0.9 1.1 -1.4 1.3 1.0 0.9 1.6 0.9 0.3 1.6
Alzheimer’s Disease (in father) 1.9 2.1 7.2 1.8 1.6 1.5 1.8 0.3 1.4 0.6 -2.7 1.4 1.0 1.5 -0.3 1.3 1.1 1.3
Alzheimer’s Disease (including proxy) 2.1 3.0 9.5 2.1 1.4 1.6 2.0 -0.4 1.6 1.2 -3.1 2.2 1.4 1.6 1.2 1.4 0.8 2.1
Crohns Disease (2017) 1.0 2.2 4.8 1.5 1.3 1.5 1.1 1.9 1.8 1.8 -0.8 1.6 2.2 1.8 0.2 2.0 0.2 1.0
Irritable Bowel Disease (IBD) 0.3 0.7 3.9 0.8 1.0 0.3 0.3 2.0 0.2 1.0 -0.1 0.5 1.0 0.4 -0.1 0.7 -1.1 -0.1
Ulcerative Colitis (UC) 0.3 0.5 1.9 -0.1 0.3 -0.7 -0.6 1.4 -0.9 0.1 0.3 -0.5 -0.2 -0.7 -0.5 -0.5 -1.2 -0.8
Major Depression (MDD) 1.9 2.3 3.8 -1.9 -2.0 -1.6 -1.8 -0.9 -1.3 -1.7 1.5 -1.8 -1.5 -1.4 -0.8 -1.5 -1.1 -1.2
Reaction Time 0.2 0.5 2.8 -0.4 -1.7 -0.2 -0.7 -1.3 -0.0 -0.3 -0.5 -0.2 -0.2 -0.1 0.3 -0.1 1.1 0.4
Verbal and Numeric Reasoning (VNR) 0.8 1.9 3.3 1.8 1.5 1.6 1.8 -0.1 1.3 1.2 -1.2 1.5 1.5 1.4 1.1 1.4 0.8 1.7
Breast Cancer 0.1 0.1 0.5 0.7 0.5 0.4 0.2 -0.5 0.3 0.5 0.4 -0.4 0.1 0.1 0.0 0.0 -0.3 0.3
Ovarian Cancer 0.2 0.3 2.3 -0.1 -0.5 -0.1 -0.5 -1.5 -0.2 -0.6 0.0 -0.2 -0.4 0.0 -0.5 -0.1 1.1 -0.1
Prostate Cancer 1.1 1.5 3.8 1.1 0.3 1.0 0.7 -0.0 1.3 0.8 -1.9 1.8 1.4 1.3 1.3 1.3 1.0 1.6
Age at First Birth 0.2 0.3 4.6 0.1 -0.0 -0.1 0.3 2.2 -0.1 -0.1 0.0 -0.2 -0.3 -0.2 0.1 -0.2 -0.4 -0.3
Bipolar Disorder (2011) 0.8 0.8 7.0 -0.6 -0.4 -0.7 -0.5 -1.0 -1.3 -0.7 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.4 0.6 3.7 0.5 0.3 1.0 1.0 1.9 0.8 0.2 0.8 0.8 0.6 0.6 -0.4 0.6 -0.3 -0.1
Coronary Artery Disease (CAD) 0.2 0.2 1.4 0.1 1.2 -0.1 0.6 0.3 -0.4 0.0 0.5 -0.1 -0.4 -0.4 0.9 -0.3 0.5 -0.0
Crohns Disease (2012) 0.5 0.9 2.2 1.0 1.0 0.8 0.9 0.8 1.0 1.5 -0.7 0.7 1.5 0.9 -0.0 1.2 -0.4 0.5
Mean Putamen Volume 0.2 0.2 0.8 -0.1 -0.4 0.1 -0.3 -0.2 0.3 0.3 -0.9 0.1 0.8 0.4 0.7 0.6 0.3 -0.2
Fasting Glucose 0.1 0.1 0.5 -0.2 0.1 0.1 -0.1 -0.0 0.1 0.1 0.5 -0.1 0.7 0.3 -0.3 0.5 0.1 0.0
HbA1C 0.5 0.6 2.4 0.4 1.1 -0.2 0.5 1.6 0.0 0.9 0.7 0.2 1.1 0.1 1.0 0.6 -0.6 0.4
HDL Cholesterol 0.4 0.7 4.1 0.6 0.6 0.7 -0.0 -2.0 0.4 0.5 -1.0 0.6 0.3 0.7 0.3 0.5 1.4 1.1
LDL Cholesterol 0.4 0.7 5.3 0.7 1.0 0.4 0.7 2.3 0.3 0.2 0.6 0.3 0.3 0.3 0.9 0.3 -0.2 1.1
Lupus 1.9 2.8 7.0 -1.3 -0.8 -1.7 -1.1 -2.4 -1.6 -1.6 0.8 -1.5 -1.7 -1.8 -1.7 -1.8 -2.7 -1.7
Neuroticism (2016) 0.8 1.2 2.3 1.1 1.0 1.0 1.1 -1.0 1.0 0.8 -0.4 0.9 1.5 1.2 1.2 1.4 1.3 1.2
Primary Biliary Cirrhosis 0.3 0.5 2.2 0.7 0.6 0.5 1.1 1.5 0.1 0.6 0.6 0.4 0.3 0.1 1.1 0.2 -0.6 0.1
Rheumatoid Arthritis 0.9 1.3 2.0 -1.2 -1.1 -1.2 -1.2 -0.9 -1.2 -1.3 0.2 -1.4 -1.1 -1.1 -1.4 -1.1 -0.8 -1.3
Schizophrenia (2014) 0.8 1.7 15.1 -1.1 -0.5 -1.4 -1.2 -3.9 -1.2 -0.6 1.1 0.1 -0.8 -1.0 -0.1 -0.9 0.2 -0.6
Triglycerides 0.6 0.9 2.2 0.9 0.8 1.1 1.2 1.5 1.2 0.6 -0.5 0.8 1.1 1.2 -0.4 1.1 0.1 0.8
Type 2 Diabetes (T2D) (2012) 2.1 2.5 5.6 -1.5 -0.8 -1.5 -1.6 0.9 -1.7 -1.4 2.4 -1.8 -1.8 -1.8 -1.2 -1.8 -1.3 -1.6
Ulcerative Colitis 1.1 1.6 4.4 -0.8 0.4 -1.4 -0.7 0.8 -1.7 -0.0 1.9 -1.5 -0.7 -1.6 -0.3 -1.2 -2.1 -1.6
Blood Eosinophil Count 0.0 0.2 0.7 -0.2 -0.1 0.1 -0.6 0.3 0.6 0.2 -0.8 0.0 0.6 0.4 -0.2 0.5 0.8 0.0
Blood Platelet Count 0.3 3.9 7.8 -2.5 -1.7 -2.5 -2.5 -2.8 -2.2 -2.2 1.2 -1.8 -1.7 -2.1 -1.5 -1.9 -0.7 -1.1
Blood Red Count 0.2 1.7 8.3 1.3 2.9 0.6 2.1 1.4 0.1 0.7 -0.5 1.0 1.4 0.7 1.8 1.0 0.0 0.1
Blood White Count 0.0 0.4 1.4 -0.1 0.1 -0.3 -0.3 0.7 0.5 0.6 -1.2 0.1 0.7 0.3 1.0 0.5 0.7 0.3
Heel T-Score 1.1 9.1 18.9 -3.2 -1.2 -2.6 -2.4 1.1 -2.4 -3.5 4.2 -3.0 -2.8 -2.8 -4.3 -2.8 -3.5 -3.6
BMI 0.6 3.7 36.8 1.5 1.9 1.5 1.6 6.1 1.1 0.8 -0.4 0.7 1.3 0.8 0.7 0.9 -0.9 0.5
Height 0.1 2.7 5.0 1.4 0.1 1.2 1.1 2.1 1.9 1.5 -1.9 1.3 2.1 1.7 0.9 1.9 1.6 2.2
Waist Hip Ratio (WHR) 0.2 0.7 2.5 1.0 0.7 0.6 0.3 -0.2 0.9 0.9 -0.7 1.2 1.6 1.0 0.4 1.2 0.1 0.2
Systolic Blood Pressure 1.4 7.2 11.7 2.5 2.7 2.5 2.2 1.3 2.5 3.3 -2.6 2.6 2.7 2.7 3.0 2.7 3.4 2.9
Smoking Status 0.5 1.3 6.0 1.7 2.4 1.1 2.0 0.7 0.8 0.4 -1.0 0.2 1.1 0.8 0.5 0.9 -0.3 0.6
Allergy or Eczema 0.3 0.7 2.1 1.4 1.2 0.6 1.4 0.6 0.5 0.6 -0.2 0.4 0.7 0.5 0.9 0.5 -0.5 1.2
Cardiovascular Disease 0.5 1.7 6.6 1.1 0.6 1.2 0.6 2.6 1.5 0.6 -2.1 1.3 1.5 1.4 0.6 1.5 0.3 0.7
Hypothyroidism (self reported) 0.2 0.5 1.4 0.4 0.6 0.5 0.4 0.8 0.6 0.9 -0.9 0.9 1.2 0.7 0.4 0.9 0.4 0.5
Respiratory disease 0.3 0.7 1.8 0.7 0.9 1.0 0.8 0.0 0.9 1.0 -0.5 1.3 0.6 0.9 0.6 0.8 1.2 0.5
Type 2 Diabetes (T2D) (2018) 0.4 0.7 3.3 -0.8 -0.3 -0.7 -0.5 1.8 -0.6 -1.0 0.4 -0.9 -0.7 -0.8 -0.6 -0.8 -0.5 -0.9
Lung FEV1/FVC ratio 0.3 1.8 6.0 -1.0 0.1 -1.3 -0.8 0.6 -1.1 -1.4 1.1 -1.4 -1.2 -1.5 -1.4 -1.4 -2.4 -1.6
Lung FVC 0.5 2.5 6.9 -1.5 -1.9 -0.9 -1.0 -2.6 -1.7 -1.9 1.5 -1.9 -2.2 -1.3 -0.8 -1.7 -0.2 -0.9
Neuroticism 1.4 3.3 5.7 2.0 1.5 1.7 2.0 -1.6 1.8 1.4 -1.8 1.8 1.7 1.9 2.4 1.8 1.5 2.1
Chronotype (morning person) 0.1 0.3 1.1 0.3 1.1 -0.4 0.4 -1.0 -0.8 -0.4 -0.0 -0.4 -0.2 -0.5 0.1 -0.5 -0.2 -0.6
Hair Pigment 0.0 0.7 2.4 -0.4 -1.4 -0.7 -0.6 0.6 -0.5 -0.9 0.2 -0.4 -0.6 -0.7 -1.5 -0.7 -1.4 -0.4
Tanning 0.1 0.9 5.7 -0.7 -2.4 -0.4 -0.9 -1.2 -0.2 -1.4 0.9 -0.0 -0.8 -0.3 -1.4 -0.5 -0.2 -0.1
Hand grip strength (left) 0.4 1.0 2.6 -1.6 -1.1 -1.1 -1.3 0.3 -0.8 -1.0 1.6 -0.9 -1.0 -0.9 -0.8 -0.9 0.3 -0.4
Number of treatments/medications taken 0.4 0.8 5.5 0.5 0.9 0.3 0.1 2.4 0.4 0.3 -1.1 0.7 0.7 0.4 1.0 0.5 0.5 0.8
Average weekly spirits intake 0.2 0.3 3.7 0.1 0.3 -0.1 0.4 1.9 0.0 -0.2 0.4 0.3 0.5 -0.0 0.2 0.2 -0.4 0.0
Sensitivity / hurt feelings 0.2 0.4 3.6 -0.0 0.3 0.0 0.2 -1.9 0.2 0.4 -0.5 0.4 0.2 0.3 0.6 0.3 0.5 0.5
Frequency of depressed mood in last 2 weeks 0.2 0.3 2.3 -0.2 -1.0 -0.3 -0.2 -1.5 0.0 -0.6 0.1 0.0 -0.2 0.0 -0.4 -0.1 -0.8 0.2
Hearing difficulty/problems: Yes 0.9 1.4 3.2 -1.2 -0.7 -1.1 -1.3 0.6 -1.2 -0.8 1.4 -1.3 -1.1 -1.3 -1.3 -1.2 -1.8 -1.1
Relative age of first facial hair 3.0 6.1 12.5 3.0 3.4 2.1 3.5 -0.3 1.8 2.5 -2.6 2.4 2.4 2.0 2.9 2.2 0.9 2.8
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 2.1 1.2 1.2 1.0 1.5 -0.4 0.5 0.1 0.0 0.4 0.1 0.5 0.0 0.3 -0.5 0.5
Ever used hormone-replacement therapy (HRT) 0.2 0.2 1.3 0.4 1.1 0.1 0.9 0.7 0.3 0.2 -0.1 -0.2 0.1 0.1 0.3 0.1 0.5 0.1
Ever had hysterectomy (womb removed) 0.4 0.5 1.7 -0.5 1.3 -0.7 -0.0 0.8 -0.9 -0.1 0.2 -0.8 -0.7 -0.9 -0.2 -0.8 -0.1 -0.9
Systolic blood pressure, automated reading 2.0 5.8 10.0 2.1 2.3 2.6 2.0 2.4 2.6 2.6 -1.9 2.2 2.4 2.4 2.6 2.4 3.2 2.3
Eye problems/disorders: Diabetes related eye disease 4.2 4.6 9.2 -2.1 -2.4 -2.2 -2.3 -2.1 -2.0 -2.5 0.6 -2.2 -2.0 -2.0 -3.0 -1.9 -1.5 -2.4
Angina 0.3 0.4 1.2 -0.7 -1.1 -0.9 -0.8 -0.5 -0.4 -0.4 -0.3 -0.2 -0.0 -0.6 0.2 -0.3 -1.1 -0.1
Medication for hormone replacement therapy 2.3 2.6 3.9 -1.7 -1.4 -2.0 -1.6 -1.6 -1.9 -1.8 1.1 -1.8 -1.8 -1.9 -0.7 -1.9 -0.9 -1.3
Vitamin and mineral supplements 0.3 0.4 1.0 0.6 -0.1 0.7 0.3 1.0 0.9 0.6 -0.3 0.9 0.4 0.7 -0.1 0.6 0.6 0.9
Supplements: Zinc 3.3 3.6 6.4 -2.5 -1.9 -2.0 -2.3 -1.5 -2.2 -1.3 2.3 -2.5 -1.6 -2.1 -1.2 -1.8 -1.3 -1.0
Medication: Co-codamol 0.4 0.5 1.8 0.4 0.3 0.7 0.5 0.4 0.6 0.8 -0.5 1.3 0.9 0.8 0.8 0.8 0.3 0.3
Medication: Metformin 0.2 0.3 0.7 -0.3 0.4 -0.7 -0.2 0.6 -0.7 0.0 0.4 -0.7 -0.2 -0.7 -0.1 -0.5 -0.9 -0.4
Diabetes (father) 2.0 2.4 4.1 1.5 0.8 1.7 1.7 1.6 1.6 1.3 -1.6 1.5 1.2 1.6 1.3 1.4 1.9 2.0
Diabetes (mother) 0.3 0.4 1.9 -0.4 -0.3 -0.4 -0.6 0.7 -0.2 -0.6 -0.5 -0.7 -0.3 -0.3 -1.4 -0.3 -0.4 -1.1
Severe depression (siblings) 0.3 0.3 1.3 -0.1 0.5 -0.4 0.4 -1.1 -0.5 -0.4 -0.3 -0.4 -0.4 -0.5 0.9 -0.5 -0.4 -0.3
Pack years adult smoking proportion 0.8 1.2 2.7 -1.4 -1.1 -1.0 -1.4 1.5 -0.9 -1.1 0.7 -0.9 -1.0 -1.1 -0.7 -1.0 -0.7 -1.6
Impedance of leg (right) 0.7 3.4 9.3 -2.0 -2.3 -2.0 -2.3 -3.0 -1.5 -1.3 1.7 -2.0 -1.5 -1.4 -1.5 -1.5 -0.8 -1.5
Leg fat-free mass (left) 0.6 3.1 15.9 1.6 1.4 1.4 1.8 4.0 1.4 1.3 -1.7 1.7 1.9 1.2 1.0 1.5 0.7 1.6
Trunk fat percentage 0.4 1.5 16.9 0.8 0.6 0.6 0.5 4.1 0.9 0.6 -0.6 0.5 1.3 0.5 0.2 0.8 -0.3 0.5
Hand grip strength (right) 0.3 0.9 3.2 -1.8 -1.3 -1.1 -1.6 0.6 -0.6 -0.6 0.7 -0.7 -0.6 -0.7 -0.8 -0.7 0.7 -0.5
Townsend deprivation index at recruitment 0.4 0.6 2.1 -1.0 -0.6 -0.9 -0.9 -0.3 -0.8 -1.1 1.4 -0.8 -0.3 -0.8 -0.0 -0.6 -0.3 -0.4
Current tobacco smoking 1.0 1.6 3.5 1.1 1.8 0.9 1.5 1.3 1.0 1.4 -0.3 0.7 1.6 1.0 1.9 1.3 0.7 1.0
Average weekly fortified wine intake 3.8 4.4 6.8 -2.6 -2.5 -2.1 -2.6 -1.2 -2.2 -1.9 1.6 -2.1 -2.2 -2.1 -2.2 -2.1 -1.4 -2.2
Maternal smoking around birth 0.8 1.2 2.7 -1.4 -1.5 -1.4 -1.6 -0.5 -1.1 -1.3 0.3 -0.5 -1.0 -1.2 -1.0 -1.1 -0.6 -0.4
Fed-up feelings 0.9 1.6 5.1 1.2 0.4 1.0 1.0 -0.7 1.0 1.1 -2.0 1.0 1.1 1.1 2.3 1.1 1.2 1.4
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.1 0.4 0.2 0.3 0.0 0.1 -0.7 0.2 0.2 0.6 0.2 0.5 0.2 0.6 0.3 -0.2 0.6
Relative age voice broke 1.2 1.9 7.3 1.2 0.2 1.1 1.4 0.7 1.3 1.4 -2.7 1.3 1.3 1.3 1.8 1.3 0.6 1.4
Taking other prescription medications 1.0 1.6 3.6 1.3 1.5 1.1 1.1 1.9 1.2 0.9 -1.5 1.5 1.2 1.1 1.2 1.1 0.9 1.2
Age when periods started (menarche) 0.6 1.4 4.0 0.7 -0.3 1.3 0.2 -1.1 1.4 0.9 -0.6 1.4 0.9 1.5 0.1 1.2 2.0 1.9
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 1.4 -0.5 1.2 -0.4 -0.3 0.7 -0.3 0.2 0.2 -0.3 -0.2 -0.4 0.0 -0.3 0.2 -0.8
Heel bone mineral density (BMD) T-score, automated (left) 1.2 2.8 5.7 -1.7 -0.3 -1.4 -1.4 0.6 -1.5 -1.8 2.2 -2.0 -1.4 -1.6 -2.3 -1.5 -1.9 -2.4
Tinnitus: Yes, but not now, but have in the past 2.1 2.3 3.1 -1.4 -0.9 -1.6 -1.7 -1.2 -1.8 -1.6 1.2 -1.7 -1.5 -1.7 -1.1 -1.6 -1.6 -1.6
Qualifications: CSEs or equivalent 0.1 0.2 0.4 -0.4 -0.5 -0.5 -0.2 -0.6 -0.5 0.0 0.0 -0.3 -0.5 -0.6 -0.0 -0.6 0.3 0.0
Serious illness, injury or assault to yourself 0.4 0.5 1.4 -0.3 0.4 -0.5 -0.2 -0.9 -1.1 -0.6 1.2 -0.4 -0.8 -1.0 0.3 -0.9 -1.0 -0.0
High blood pressure 3.0 8.5 19.8 2.8 3.2 3.1 2.6 4.5 3.2 2.6 -2.2 3.0 3.4 3.1 2.1 3.2 1.4 1.9
Hayfever, allergic rhinitis or eczema 0.1 0.2 0.6 0.6 0.2 0.1 0.6 0.1 -0.1 -0.0 0.6 -0.1 -0.2 -0.2 -0.5 -0.2 -0.8 0.5
Multivitamins +/- minerals 0.3 0.3 0.7 -0.8 0.3 -0.8 -0.3 -0.1 -0.7 -0.6 0.8 -0.7 -0.3 -0.7 0.4 -0.5 -0.1 -0.7
Stomach or abdominal pain in last month 0.2 0.2 1.2 -0.5 -0.5 -0.8 -0.7 0.6 -0.2 -0.4 -0.4 -0.1 0.1 -0.4 1.1 -0.1 0.2 0.2
Supplements: Glucosamine 0.3 0.4 0.8 0.6 0.5 0.9 0.4 -0.5 0.7 0.9 0.3 0.3 0.9 0.8 -0.3 0.8 -0.2 0.6
Diverticular disease/diverticulitis (self-reported) 2.2 2.7 5.0 -1.8 -0.6 -2.0 -2.1 -0.7 -1.7 -1.7 1.0 -2.0 -2.2 -1.9 -0.7 -2.1 -0.4 -1.7
Medication: Atenolol 0.9 1.1 2.2 0.8 0.2 1.2 0.7 1.5 1.4 0.0 -1.3 1.2 1.3 1.4 0.5 1.3 0.5 0.8
Medication: Levothyroxine sodium 1.0 1.7 3.2 1.3 1.2 1.4 1.3 0.5 1.4 1.1 -1.0 1.8 1.4 1.5 1.3 1.4 1.3 1.3
Sitting height 0.1 0.4 0.8 -0.9 -0.8 -0.9 -0.7 0.1 -0.8 -0.4 0.2 -0.7 -0.4 -0.8 -0.4 -0.6 -0.8 -0.1
Chronic bronchitis/emphysema (father) 0.2 0.3 1.1 -1.0 -0.5 -0.6 -1.0 -0.8 -0.3 0.2 0.2 -0.1 -0.3 -0.5 0.2 -0.3 0.3 0.2
High blood pressure (mother) 0.2 0.2 1.6 0.2 -0.1 -0.2 0.3 1.3 -0.4 -0.4 0.4 -0.8 -0.3 -0.3 0.0 -0.3 -0.5 0.3
Body mass index (BMI) 0.6 2.6 21.0 1.2 2.0 1.0 1.5 4.6 1.0 0.9 -0.6 1.2 1.5 0.7 1.2 0.9 -0.0 0.9
Impedance of leg (left) 0.8 3.8 9.5 -2.1 -2.2 -2.1 -2.5 -3.1 -1.6 -1.6 1.7 -2.2 -1.7 -1.6 -1.6 -1.6 -1.1 -1.9
Leg predicted mass (left) 0.6 3.0 15.8 1.6 1.4 1.4 1.8 4.0 1.4 1.3 -1.6 1.6 1.8 1.2 1.0 1.4 0.6 1.5
Trunk fat mass 0.6 2.6 23.1 1.2 0.9 1.0 1.0 4.8 1.3 1.0 -1.1 1.0 1.8 0.9 0.5 1.2 -0.1 1.0
Waist circumference 0.8 3.0 15.4 1.7 2.1 1.4 1.7 3.9 1.3 1.3 -1.1 1.6 2.0 1.1 1.2 1.4 0.2 1.3
Number of incorrect matches in round 3.0 5.1 9.3 2.1 2.2 2.5 2.0 1.8 2.7 3.0 -1.0 2.2 2.5 2.7 1.0 2.7 2.2 1.8
Past tobacco smoking 1.3 2.4 6.5 -2.4 -2.5 -1.9 -2.6 -0.8 -1.4 -0.8 1.6 -1.1 -1.5 -1.5 -0.3 -1.4 0.6 -1.1
Alcohol usually taken with meals 0.3 0.4 1.6 0.5 0.6 0.2 0.6 -1.2 -0.1 0.8 0.6 -0.0 -0.1 0.0 1.3 -0.0 -0.4 1.0
Nervous feelings 0.4 0.8 3.8 0.1 0.4 0.1 0.0 -1.5 0.6 0.9 0.3 0.7 0.3 0.4 1.4 0.4 2.0 1.4
Frequency of tenseness / restlessness in last 2 weeks 0.9 1.4 6.4 0.4 -0.7 0.3 0.1 -1.4 0.8 0.7 -1.8 0.9 0.9 0.8 2.5 0.8 1.3 1.4
Hearing difficulty/problems with background noise 0.1 0.2 0.6 0.3 0.3 0.5 -0.1 -0.0 0.4 0.6 0.5 0.7 0.5 0.5 0.7 0.5 0.2 0.6
Hair/balding pattern: Pattern 2 0.7 0.9 5.7 1.6 1.0 0.5 1.3 -2.4 0.1 -0.5 -1.2 -0.0 0.0 0.2 -0.2 0.1 -1.0 0.2
Had menopause 0.4 0.5 1.6 -0.1 0.3 0.4 0.3 1.0 0.8 0.9 0.0 0.7 0.7 0.6 1.1 0.8 1.3 0.7
Had other major operations 0.6 0.7 2.8 -0.4 0.7 -0.8 -0.0 0.9 -1.1 -0.4 1.7 -1.1 -0.9 -1.1 -0.5 -1.1 -0.5 -0.2
Forced vital capacity (FVC) 1.0 3.8 6.7 -1.9 -1.7 -2.0 -1.6 -1.9 -2.3 -2.2 1.5 -2.6 -2.1 -2.1 -1.9 -2.1 -1.7 -1.4
Heel bone mineral density (BMD) T-score, automated (right) 0.8 1.9 5.7 -1.2 0.0 -0.8 -0.9 1.7 -0.8 -1.4 2.4 -1.3 -1.0 -1.1 -1.7 -1.0 -1.5 -2.0
Ever unenthusiastic/disinterested for a whole week 6.2 7.6 12.4 -3.4 -2.0 -3.2 -3.1 0.5 -2.8 -2.1 2.7 -2.9 -2.5 -3.0 -2.7 -2.8 -2.8 -3.5
Qualifications: None of the above 0.5 1.0 3.8 0.5 0.4 0.7 0.4 0.1 0.8 0.5 -1.3 1.3 1.2 0.9 2.0 1.0 1.3 0.5
Financial difficulties in last 2 years 0.2 0.3 0.9 0.9 0.8 0.2 0.9 -0.6 -0.4 -0.2 -0.6 -0.0 -0.5 -0.3 -0.8 -0.5 -0.6 0.1
Mouth/teeth dental problems 0.2 0.3 2.5 0.1 0.8 -0.4 0.1 1.6 -0.3 0.4 0.3 -0.7 -0.2 -0.3 -0.3 -0.3 0.1 0.3
Heart attack 1.4 1.8 2.6 1.3 1.4 1.3 1.0 0.7 1.6 1.2 -1.1 1.5 1.5 1.4 1.1 1.5 1.5 1.6
Allergy 0.1 0.1 0.5 -0.0 0.5 0.1 -0.0 0.4 0.2 0.2 -0.5 0.1 0.3 0.3 0.6 0.4 0.7 0.0
Pain all over the body in last month 0.4 0.4 2.0 0.3 1.4 0.2 0.3 1.4 0.3 0.7 -0.4 0.6 0.7 0.3 0.7 0.5 -0.0 -0.1
Diabetes (self-reported) 0.4 0.6 1.5 -0.6 -0.3 -0.8 -0.8 1.2 -0.7 -0.8 -0.6 -0.9 -0.4 -0.8 -0.9 -0.7 -0.7 -0.6
Hayfever/allergic rhinitis (self-reported) 0.8 1.0 2.1 0.9 -0.1 1.3 1.0 0.8 1.4 1.1 0.4 1.4 1.2 1.2 0.5 1.3 0.4 1.2
Medication: Ramipril 1.2 1.5 3.3 0.8 0.5 1.3 0.8 1.5 1.4 1.4 -0.4 1.8 1.7 1.5 0.8 1.7 0.3 0.7
Medication: Simvastatin 0.2 0.3 2.3 -0.3 -0.3 -0.0 -0.7 1.5 0.5 0.1 -0.9 0.5 0.5 0.4 0.5 0.5 0.3 0.1
Fluid intelligence score 0.2 0.5 1.5 0.6 -0.3 0.7 0.4 -0.1 0.7 0.6 -0.8 0.4 0.5 0.7 0.3 0.6 1.1 1.2
Illnesses of siblings 0.1 0.2 0.5 0.6 0.3 0.6 0.6 -0.3 0.2 -0.4 -0.4 0.7 -0.1 0.4 -0.1 0.2 0.5 0.1
Neuroticism score 1.3 2.8 5.3 1.6 1.3 1.4 1.6 -1.4 1.6 1.4 -1.6 1.7 1.8 1.7 2.3 1.7 1.5 1.9
Weight 0.6 3.2 22.2 1.5 1.7 1.2 1.6 4.7 1.3 1.3 -1.1 1.4 1.9 1.0 1.1 1.3 0.3 1.5
Impedance of arm (right) 0.2 1.0 5.9 -0.4 -1.9 -0.5 -1.3 -2.4 -0.2 -0.5 0.1 -1.1 -0.6 -0.1 -1.1 -0.3 0.2 0.0
Arm fat percentage (right) 0.5 1.9 20.2 1.0 1.2 0.8 1.0 4.5 0.9 0.5 -0.6 0.7 1.2 0.6 0.2 0.8 -0.4 0.5
Trunk fat-free mass 0.6 3.5 12.9 1.7 1.4 1.6 1.8 3.6 1.7 1.5 -1.7 2.1 2.1 1.6 1.4 1.8 0.9 1.7
Hip circumference 0.6 2.7 17.3 1.5 1.7 1.3 1.5 4.2 1.2 1.3 -1.1 1.2 1.6 1.0 1.1 1.2 0.5 1.6
Time employed in main current job 0.2 0.2 1.6 -0.0 0.3 0.2 -0.2 1.3 0.3 0.2 0.6 0.2 -0.2 0.0 -0.1 -0.0 0.4 0.1
Alcohol intake versus 10 years previously 0.3 0.5 1.5 -0.3 -0.1 -0.5 -0.6 -1.2 -0.0 0.8 -1.0 0.5 0.5 -0.0 0.9 0.2 1.1 0.8
Father’s age at death 0.2 0.3 2.0 0.5 1.4 0.3 0.6 0.5 -0.0 0.3 0.1 0.1 0.3 0.1 0.5 0.2 -0.5 -0.1
Worrier / anxious feelings 0.7 1.2 2.5 1.0 1.6 0.8 1.3 -0.7 1.1 1.2 -0.1 1.2 1.6 1.1 1.2 1.3 0.4 1.0
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 3.7 0.5 -0.6 0.5 0.2 -1.4 0.7 0.5 -1.9 0.9 0.8 0.9 1.1 0.8 1.1 1.9
Falls in the last year 0.3 0.4 2.2 -0.2 0.4 -0.1 -0.1 1.2 -0.1 0.5 1.5 0.2 0.5 -0.0 1.2 0.2 0.1 0.6
Hair/balding pattern: Pattern 3 2.3 3.4 10.1 -3.2 -3.2 -1.5 -3.0 1.7 -0.8 -1.2 2.7 -1.0 -0.5 -0.9 -1.6 -0.6 -0.3 -1.5
Number of live births 0.2 0.3 2.4 0.3 0.4 0.3 0.5 0.0 0.1 0.0 -0.2 0.3 0.1 0.2 0.9 0.2 1.5 0.8
Forced expiratory volume in 1-second (FEV1) 1.5 5.0 8.6 -2.1 -1.8 -2.3 -1.8 -1.8 -2.7 -2.6 1.6 -2.9 -2.5 -2.5 -2.2 -2.5 -2.1 -1.8
Pulse rate 0.1 0.2 0.9 0.1 1.0 0.2 0.8 -0.3 0.3 0.3 0.1 0.6 0.3 0.2 -0.3 0.3 0.1 0.2
Happiness 0.1 0.1 0.9 0.3 -0.2 0.4 -0.1 -0.6 0.2 -0.4 -1.0 0.4 -0.0 0.3 -0.1 0.1 -0.0 -0.0
Noisy workplace 0.1 0.2 0.6 -0.2 -0.6 -0.3 -0.0 -0.0 -0.1 -0.4 -0.7 0.3 0.3 -0.1 0.7 0.1 -0.8 -0.2
Qualifications: A levels/AS levels or equivalent 0.3 0.6 2.9 1.3 1.0 0.9 1.7 -0.3 0.5 0.6 -0.3 0.1 0.3 0.6 -0.2 0.5 -0.3 0.7
Serious illness, injury or assault of a close relative in last 2 years 0.1 0.1 0.4 -0.1 0.2 -0.1 -0.2 -0.1 -0.3 -0.6 -0.0 0.1 -0.4 -0.3 -0.1 -0.4 0.3 0.2
Mouth/teeth dental problems: Dentures 0.1 0.1 0.4 0.0 -0.3 0.1 -0.1 -0.6 -0.1 -0.6 -0.0 0.5 -0.2 -0.1 0.1 -0.2 -0.5 -0.5
Asthma 0.5 0.9 2.4 0.6 0.0 1.3 1.0 -0.3 1.3 0.9 -0.9 1.2 0.6 1.2 -0.5 1.0 1.5 0.6
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.6 -0.7 -1.2 -0.5 -0.9 0.9 -0.3 -0.8 -0.2 -0.3 -0.3 -0.2 -0.2 -0.2 0.6 0.0
Medication: Cholesterol lowering 0.2 0.3 1.3 -0.5 -1.1 -0.6 -1.1 0.4 0.2 -0.5 -1.1 -0.2 0.2 -0.1 0.1 0.0 -0.4 0.1
Depression (self-reported) 1.9 2.2 4.0 -1.4 -1.2 -1.5 -1.2 -1.3 -1.6 -1.6 1.5 -1.9 -2.0 -1.7 -1.0 -1.8 -1.1 -1.4
Medication: Lansoprazole 0.3 0.4 1.1 -0.5 -0.5 -0.7 -1.0 0.7 -0.8 -0.5 0.1 -0.8 -0.4 -0.7 -0.2 -0.5 -0.7 -0.3
Prospective memory result 0.2 0.3 1.3 0.3 1.0 -0.1 0.6 0.0 -0.2 0.3 -0.9 0.2 0.2 -0.1 1.1 0.0 -0.6 0.2
Lung cancer (father) 0.9 1.1 6.3 -1.1 -2.5 -0.7 -1.1 0.7 -0.6 -1.0 -0.3 -0.8 -0.8 -0.6 -0.5 -0.7 -0.9 -1.2
Illnesses of mother 0.1 0.1 0.5 -0.1 0.6 0.3 0.2 -0.1 0.2 0.2 -0.7 0.1 0.1 0.2 0.4 0.2 0.6 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 1.6 5.0 7.7 -2.0 -1.4 -2.5 -1.6 -1.6 -2.8 -2.7 1.4 -2.6 -2.6 -2.6 -2.1 -2.6 -2.3 -2.1
Pulse wave Arterial Stiffness index 1.0 1.2 3.8 0.5 0.2 0.9 1.0 1.3 1.2 1.0 -1.2 1.1 1.1 1.0 2.0 1.1 0.7 1.0
Impedance of arm (left) 0.2 0.8 3.5 -0.4 -1.6 -0.5 -1.1 -1.9 -0.3 -0.4 0.1 -1.2 -0.7 -0.2 -1.3 -0.4 -0.1 -0.2
Arm fat mass (right) 0.7 2.9 23.8 1.4 1.7 1.1 1.5 4.9 1.2 1.0 -0.8 1.2 1.7 0.9 0.9 1.1 0.0 1.0
Trunk predicted mass 0.6 3.4 12.3 1.7 1.4 1.6 1.9 3.5 1.7 1.5 -1.7 2.1 2.1 1.6 1.3 1.8 0.9 1.7
Standing height 0.1 0.8 2.2 0.8 -0.6 0.6 0.2 0.8 1.0 0.9 -1.1 0.7 1.2 1.0 0.1 1.1 0.8 1.5
Length of working week for main job 0.4 0.4 1.4 -0.1 -0.6 -0.2 -0.4 -1.0 -0.4 -1.0 -1.2 -0.7 -0.5 -0.3 -0.5 -0.4 -0.6 -0.4
Exposure to tobacco smoke at home 0.7 0.8 2.7 0.8 0.0 0.9 0.8 -0.4 1.0 0.7 -0.6 1.6 0.9 1.0 0.6 0.9 0.9 1.3
Breastfed as a baby 1.4 1.7 3.6 1.2 -0.2 1.9 1.3 0.9 1.7 1.1 -0.8 1.4 1.1 1.7 0.4 1.5 1.3 1.7
Tense / ‘highly strung’ 0.9 1.5 4.1 1.0 0.3 1.1 1.3 -1.9 1.2 0.5 -0.9 1.2 0.7 1.1 2.0 0.9 1.6 1.4
Seen doctor (GP) for nerves, anxiety, tension or depression 0.1 0.1 0.4 -0.5 -0.6 -0.3 -0.4 0.2 -0.1 -0.0 0.6 0.2 -0.1 -0.2 0.6 -0.1 -0.6 -0.4
Hair/balding pattern: Pattern 4 0.6 1.5 5.8 -2.0 -2.2 -1.2 -2.4 1.1 -0.7 -0.3 0.7 -0.7 -0.5 -0.8 -0.5 -0.6 -0.4 -1.5
Birth weight of first child 0.4 0.7 3.2 1.1 0.0 0.9 1.2 0.5 0.6 0.1 -1.8 0.3 -0.1 0.6 -0.7 0.2 0.5 1.6
Peak expiratory flow (PEF) 0.6 1.4 3.1 -0.4 0.2 -1.0 -0.2 -0.5 -1.6 -1.3 0.6 -1.2 -1.6 -1.3 -1.8 -1.5 -1.7 -0.8
Pulse wave reflection index 0.4 0.4 3.1 0.7 0.4 0.4 0.8 1.8 0.1 0.1 0.1 -0.5 0.1 0.1 1.1 0.1 -0.6 -0.1
Ever highly irritable/argumentative for 2 days 0.8 0.9 3.2 -0.8 -1.1 -0.8 -0.9 0.9 -0.8 -0.6 0.8 -0.6 -0.6 -0.9 -1.1 -0.8 -1.8 -1.0
Loud music exposure frequency 0.6 0.7 1.8 1.0 1.2 1.0 1.4 0.5 0.6 0.9 -0.9 0.7 0.9 0.8 0.2 0.8 0.4 0.5
Qualifications: O levels/GCSEs or equivalent 0.4 0.6 2.6 0.5 0.3 -0.4 0.3 0.3 -0.4 -0.4 0.7 -1.2 -0.9 -0.7 -1.6 -0.8 -1.2 -0.1
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 2.1 -0.4 -1.2 0.3 -0.4 -1.4 0.4 -0.4 -0.1 0.5 0.6 0.6 -0.3 0.6 0.5 -0.4
Blood clot in the leg (DVT) 0.2 0.3 2.2 0.1 0.4 -0.2 0.3 -0.3 -0.3 0.7 -0.6 -0.3 0.0 -0.4 1.5 -0.2 1.0 0.1
Medication: Paracetamol 0.2 0.3 0.8 -0.1 -0.6 -0.1 -0.4 0.9 0.4 -0.3 -0.8 0.6 0.6 0.4 0.1 0.5 0.8 0.4
Headache pain in last month 0.4 0.7 2.0 -0.2 -0.1 -0.2 -0.5 1.2 0.3 1.3 -0.1 0.5 0.9 0.2 1.4 0.5 1.4 1.4
Medication for cholesterol, blood pressure or diabetes 1.0 1.6 4.5 -1.1 -0.3 -1.1 -0.7 -1.9 -1.4 -0.6 2.1 -1.3 -1.4 -1.3 -0.9 -1.4 -0.4 -1.4
Glaucoma (self-reported) 0.6 0.7 3.1 -0.5 -0.3 -0.8 -0.5 0.2 -0.7 -0.6 -0.0 -0.4 -0.9 -0.8 -1.2 -0.8 -1.8 -1.0
Gout (self-reported) 0.5 0.6 3.5 0.7 0.8 0.8 0.6 1.9 0.9 -0.1 0.9 0.6 0.3 0.7 -1.1 0.5 -0.2 -0.0
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 2.1 0.9 1.1 1.0 0.9 0.7 1.1 1.1 -1.3 1.3 1.4 1.2 0.9 1.3 1.2 1.0
Medication: Amlodipine 1.1 1.6 7.3 1.4 1.5 1.3 1.0 2.7 1.5 0.4 -0.5 1.2 1.3 1.3 0.4 1.3 0.0 0.1
Medication: Ventolin 100micrograms inhaler 0.9 1.2 5.0 -1.2 -1.6 -1.0 -1.0 -2.2 -1.0 -1.0 0.8 -0.3 -1.2 -1.0 -0.4 -1.1 0.4 -0.4
Birth weight 0.2 0.4 2.1 0.5 -0.7 0.1 0.4 -0.4 -0.2 0.1 -0.7 -0.1 -0.3 -0.0 1.0 -0.2 0.9 1.5
Chronic bronchitis/emphysema (mother) 2.5 2.9 6.3 -1.6 -1.0 -2.0 -1.4 -2.5 -2.1 -1.7 0.8 -1.5 -1.9 -2.2 -1.4 -2.1 -1.6 -1.1
High blood pressure (siblings) 0.1 0.2 1.3 -0.0 0.3 -0.2 -0.3 -0.4 0.3 1.1 0.1 0.1 0.7 0.2 0.6 0.4 -0.0 0.4
Forced vital capacity (FVC), Best measure 1.1 4.1 6.6 -1.7 -1.2 -2.2 -1.3 -2.1 -2.6 -2.4 1.1 -2.3 -2.4 -2.4 -2.0 -2.4 -2.0 -1.7
Body fat percentage 0.4 1.4 18.0 0.5 0.8 0.3 0.4 4.2 0.6 0.3 -0.3 0.4 1.0 0.3 -0.1 0.5 -0.7 0.1
Leg fat percentage (right) 0.4 1.4 15.2 0.4 1.1 0.2 0.5 3.9 0.6 0.6 0.1 0.7 1.3 0.2 0.5 0.6 -0.2 0.3
Arm fat-free mass (right) 0.3 1.8 12.0 0.9 1.2 0.8 1.2 3.5 1.0 1.0 -1.0 1.4 1.5 0.8 0.9 1.1 0.4 0.8
Exposure to tobacco smoke outside home 1.2 1.6 2.7 -1.0 -0.8 -1.2 -1.0 -1.2 -1.2 -1.6 1.5 -1.2 -1.1 -1.4 -1.3 -1.4 -1.5 -1.2
Comparative body size at age 10 0.6 1.6 9.9 -0.2 0.3 -0.4 -0.2 3.1 -0.8 -1.0 1.6 -1.2 -0.4 -0.8 -1.2 -0.7 -2.0 -1.5
Number of full brothers 0.1 0.2 1.1 -0.2 0.1 -0.4 -0.3 -1.0 -0.3 -0.0 -0.9 -0.4 0.3 -0.2 0.3 -0.0 -0.3 -0.1
Worry too long after embarrassment 0.8 1.4 2.5 0.7 0.5 1.1 0.9 0.8 1.6 1.6 -0.8 1.3 1.5 1.6 1.0 1.6 1.3 0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.1 3.6 -1.0 -0.8 -1.1 -0.9 -0.4 -1.0 -0.7 1.9 -1.0 -0.6 -0.9 -0.6 -0.8 -1.6 -1.2
Wheeze or whistling in the chest in last year 0.2 0.3 1.3 0.3 0.5 0.5 0.5 -0.1 0.4 0.4 0.3 0.8 0.9 0.4 1.1 0.7 -0.0 0.4
Number of children fathered 1.8 2.1 3.4 1.5 0.5 1.5 1.0 -0.1 1.6 1.6 -1.6 1.7 1.9 1.6 1.6 1.7 1.1 1.4
Reason for reducing amount of alcohol drunk: Health precaution 1.2 1.4 3.7 -0.9 -0.8 -0.9 -1.0 -1.9 -1.1 -1.9 1.3 -1.3 -1.2 -0.9 -0.7 -1.1 -1.0 -0.9
Age at first live birth 0.6 1.1 2.7 -0.5 -1.2 -0.7 -0.8 1.2 -0.7 -0.9 1.6 -0.6 -0.9 -0.8 -1.5 -0.9 -1.6 -0.9
Pulse wave peak to peak time 0.9 1.0 3.4 -0.5 -0.3 -0.9 -1.1 -1.3 -1.1 -0.8 1.0 -1.0 -1.0 -0.9 -1.9 -1.0 -0.4 -0.8
Health satisfaction 0.8 1.0 3.3 -1.6 -1.0 -1.2 -1.8 -0.6 -0.8 -1.0 0.7 -0.6 -0.8 -1.0 -0.7 -0.9 -0.3 -1.3
Shortness of breath walking on level ground 0.1 0.1 0.6 0.0 0.4 0.0 0.3 0.4 -0.0 0.2 0.3 -0.0 -0.3 -0.3 0.5 -0.3 0.4 0.7
Qualifications: College or University degree 0.3 1.0 2.8 1.5 1.2 1.4 1.7 -0.1 0.7 0.8 -0.3 1.1 0.2 0.9 0.6 0.6 -0.0 1.6
Eye problems/disorders: None of the above 1.3 1.5 4.6 1.2 0.8 1.0 1.5 0.7 1.0 1.6 -0.8 1.1 1.0 1.0 1.6 1.1 1.1 2.1
Mouth/teeth dental problems: Loose teeth 0.7 0.9 2.7 0.2 -1.5 1.0 -0.1 -0.6 1.1 0.6 -0.7 0.7 0.6 1.0 0.0 0.9 1.6 1.3
Emphysema/chronic bronchitis 0.3 0.4 1.4 0.5 0.5 0.5 0.5 -0.0 0.6 0.8 -0.6 0.5 0.3 0.4 0.9 0.3 1.2 0.4
Medication for pain relief, constipation, heartburn 0.2 0.4 2.5 -0.3 -0.2 0.0 -0.0 -1.6 -0.4 0.2 1.4 -0.4 -0.6 -0.3 0.1 -0.4 -0.3 -0.8
Neck or shoulder pain in last month 0.2 0.3 0.9 -0.5 -0.1 -0.6 -0.6 0.0 -0.3 0.1 0.5 -0.9 0.0 -0.4 1.0 -0.2 0.8 0.8
Medication: Blood pressure 2.7 4.8 10.7 2.5 1.6 2.4 1.9 3.3 2.4 1.5 -2.4 2.3 2.4 2.3 1.4 2.4 0.9 2.3
Angina (self-reported) 0.3 0.4 1.5 -0.7 -1.2 -0.9 -0.9 -0.2 -0.3 -0.3 -0.3 -0.1 0.0 -0.6 0.4 -0.3 -1.0 -0.0
Migraine (self-reported) 0.2 0.2 1.0 -0.4 -0.7 -0.4 -0.6 0.1 -0.0 0.8 0.0 0.2 0.4 -0.1 1.0 0.1 0.4 0.7
Medication: Ibuprofen 0.4 0.4 1.6 -0.5 -1.3 -0.5 -0.8 1.0 -0.2 -0.5 -0.8 -0.1 -0.4 -0.2 0.1 -0.3 1.1 0.5
Medication: Allopurinol 0.4 0.5 3.7 -0.1 0.1 0.2 -0.2 1.3 0.4 -0.7 1.0 -0.0 -0.0 0.2 -1.9 0.0 -0.6 -0.7
Medication: Omeprazole 2.6 3.2 6.1 2.2 2.4 1.4 2.0 1.6 1.2 1.5 -1.3 2.1 2.0 1.3 2.5 1.5 0.5 2.2
Medication: Seretide 50 evohaler 0.3 0.4 2.0 0.1 0.9 -0.1 0.1 0.3 0.1 1.0 0.6 0.4 0.3 -0.2 1.4 -0.0 0.8 0.4
Mean time to correctly identify matches 0.1 0.2 0.8 -0.1 -0.9 0.2 -0.4 -0.9 0.3 -0.2 -0.6 0.0 -0.0 0.2 0.2 0.1 0.8 0.1
Heart disease (mother) 0.1 0.1 0.3 0.1 0.0 -0.1 -0.3 0.4 0.2 0.0 -0.1 0.3 -0.1 0.1 -0.5 -0.0 0.4 0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.9 2.3 3.4 1.6 1.8 1.8 1.8 1.2 1.7 0.7 -1.2 1.7 1.5 1.8 1.1 1.7 0.7 1.6
Whole body fat mass 0.6 2.4 22.8 1.1 1.2 0.8 1.0 4.8 1.1 0.8 -0.8 1.0 1.6 0.8 0.5 1.1 -0.2 0.8
Leg fat mass (right) 0.6 2.5 22.1 1.1 1.5 0.9 1.2 4.7 1.1 0.9 -0.7 1.2 1.7 0.7 0.8 1.1 0.0 0.9
Arm predicted mass (right) 0.3 1.4 11.5 0.7 1.0 0.7 1.0 3.4 0.9 0.8 -0.8 1.2 1.2 0.7 0.6 0.9 0.3 0.7
Pulse rate, automated reading 0.0 0.1 0.8 -0.1 0.9 -0.3 0.4 0.6 -0.2 0.3 -0.2 0.1 0.1 -0.3 0.4 -0.1 -0.2 -0.2
Alcohol intake frequency. 0.6 1.4 6.9 0.5 1.3 0.3 0.5 0.9 0.5 1.2 -0.2 1.3 0.9 0.5 2.6 0.7 2.3 1.1
Comparative height size at age 10 0.1 0.5 4.0 -0.3 -0.8 -0.6 -0.8 2.0 -0.1 -0.3 0.9 -0.6 -0.2 -0.4 -0.2 -0.3 0.4 0.2
Number of full sisters 0.6 0.8 5.0 -0.5 -0.5 -1.1 -0.8 -2.2 -0.8 -0.5 -0.6 -0.8 -0.2 -0.7 0.9 -0.5 -0.5 -0.4
Suffer from ‘nerves’ 0.4 0.7 2.1 0.4 1.4 0.3 0.8 -0.3 0.5 1.0 -0.0 0.6 1.2 0.6 1.2 0.9 0.6 0.8
Overall health rating 0.5 1.0 3.4 0.8 -0.1 0.7 0.4 -0.2 1.0 0.5 -1.8 1.4 0.9 0.9 1.1 0.9 1.6 1.2
Chest pain or discomfort 0.5 0.7 2.6 1.0 0.5 0.6 0.6 0.1 0.3 0.9 -1.1 0.7 1.0 0.4 1.6 0.6 -0.9 1.1
Had major operations 0.5 0.6 1.1 0.5 0.8 0.7 0.4 1.0 0.7 0.8 -0.5 0.6 0.9 0.8 0.8 0.8 1.0 0.7
Age at last live birth 0.1 0.1 0.6 -0.0 -0.5 -0.2 -0.2 0.8 -0.1 -0.0 0.4 0.1 -0.2 -0.3 -0.2 -0.2 -0.6 0.4
Family relationship satisfaction 0.2 0.3 1.1 -0.2 0.3 -0.5 -0.2 -0.9 -0.7 -0.3 -0.2 -0.6 0.1 -0.6 0.5 -0.4 -1.0 -0.6
Leg pain on walking 0.2 0.2 1.6 0.6 1.3 0.2 0.7 0.0 0.1 0.5 0.2 0.2 0.0 0.0 0.5 -0.0 0.3 0.4
Qualifications: NVQ or HND or HNC or equivalent 2.1 2.5 4.7 -1.8 -1.5 -2.0 -1.7 -0.8 -1.7 -1.6 0.5 -2.2 -1.8 -1.8 -0.9 -1.8 -0.9 -1.5
Commuting to job workplace: Car/motor vehicle 2.9 3.4 5.7 -2.1 -1.5 -2.3 -2.4 -1.2 -1.9 -1.8 1.0 -1.9 -1.9 -2.3 -1.3 -2.2 -1.3 -1.8
Illness, injury, bereavement, stress in last 2 years 0.7 0.9 2.3 0.6 0.2 1.1 0.1 1.1 1.5 1.1 -0.4 0.6 1.5 1.4 0.2 1.5 0.7 0.3
Medication: Aspirin 1.0 1.3 3.1 1.2 1.8 0.9 1.2 1.5 1.1 1.3 -1.2 0.8 1.4 1.0 0.4 1.2 0.0 1.1
Supplements: Vitamin C 1.1 1.3 3.5 -1.2 -1.5 -0.8 -1.5 -1.7 -0.9 -0.8 0.2 -0.9 -0.6 -0.6 -1.4 -0.6 -1.3 -1.9
Knee pain experienced in last month 0.5 0.7 1.7 1.0 1.2 1.0 1.3 0.5 1.0 1.1 -0.3 0.9 0.8 0.9 -0.3 0.8 0.4 0.6
Hypertension (Self-reported) 3.1 8.6 15.2 2.9 2.9 3.1 2.6 3.9 3.2 2.6 -2.6 3.1 3.4 3.1 2.5 3.3 1.6 2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.9 1.1 2.9 -0.6 0.7 -1.3 -0.4 -1.1 -1.7 -0.4 -0.1 -1.5 -1.1 -1.5 -0.1 -1.4 -0.8 -0.7
Illnesses of father: Heart disease 1.3 1.9 4.5 1.2 1.5 0.8 1.4 1.8 1.2 1.6 -1.6 1.1 1.4 0.8 2.1 1.0 0.9 1.2
Illnesses of siblings: Diabetes 1.3 1.6 3.3 1.4 1.7 1.3 1.8 1.8 1.2 1.3 -0.6 0.9 1.3 1.1 1.5 1.1 0.2 0.7
Smoking status: Previous 0.8 1.2 4.5 1.7 2.1 1.2 1.7 0.7 0.9 0.4 -1.1 0.6 0.9 0.9 -0.4 0.8 -0.8 0.2
Forced expiratory volume in 1-second (FEV1), predicted 0.0 0.1 0.2 0.3 0.4 0.1 0.5 0.4 -0.1 0.2 -0.1 -0.1 0.3 0.0 -0.1 0.2 -0.3 -0.2
Whole body fat-free mass 0.5 2.9 13.6 1.5 1.4 1.4 1.7 3.7 1.5 1.3 -1.6 1.8 1.9 1.3 1.1 1.5 0.7 1.5
Leg fat-free mass (right) 0.5 2.4 13.2 1.4 1.4 1.2 1.6 3.6 1.2 1.1 -1.5 1.4 1.6 1.1 0.8 1.2 0.5 1.3
Arm fat percentage (left) 0.6 2.2 22.8 1.0 1.2 0.9 1.1 4.8 1.0 0.7 -0.8 0.7 1.3 0.7 0.2 0.9 -0.3 0.6
Average weekly red wine intake 0.1 0.2 0.5 0.5 0.0 0.6 0.0 -0.6 0.4 0.7 0.2 -0.1 0.3 0.5 -0.6 0.4 -0.7 0.2
Handedness (chirality/laterality): Left-handed 0.3 0.3 0.9 -0.7 -0.8 -0.6 -0.4 0.8 -0.7 -0.7 0.1 -0.3 -0.3 -0.5 0.9 -0.4 0.1 -0.1
Mood swings 0.2 0.4 3.0 0.4 0.4 0.1 0.4 -0.2 0.4 0.4 -0.8 0.4 0.8 0.4 1.7 0.5 0.3 0.6
Loneliness, isolation 1.0 1.4 4.1 1.6 1.4 1.2 2.0 -0.7 1.0 0.9 -1.7 1.2 0.7 1.0 0.8 0.9 0.4 1.1
Long-standing illness, disability or infirmity 0.6 0.9 2.1 -0.8 -0.7 -1.0 -0.9 0.1 -1.2 -1.2 0.9 -0.6 -0.8 -1.1 -0.3 -0.9 -1.5 -1.1
Ever had bowel cancer screening 0.4 0.5 1.2 0.7 0.3 0.5 0.7 1.0 0.9 0.3 -1.1 0.7 0.7 0.7 0.3 0.7 0.7 0.6
Diabetes diagnosed by doctor 0.4 0.7 2.5 -0.5 0.1 -0.9 -0.5 1.6 -0.7 -0.6 0.1 -0.9 -0.3 -0.9 -1.2 -0.6 -1.1 -0.6
Ever had stillbirth, spontaneous miscarriage or termination 1.1 1.2 3.6 1.2 1.9 0.8 1.5 1.7 0.2 0.7 -0.6 0.5 1.1 0.5 1.7 0.7 -0.3 1.0
Friendships satisfaction 0.4 0.5 6.4 0.0 -0.3 -0.3 0.1 -2.5 -0.2 -0.3 -0.2 -0.2 0.1 -0.1 0.1 -0.0 -0.6 -0.2
Qualifications: nursing, teaching 0.2 0.3 1.0 0.5 1.0 0.5 0.9 0.7 0.2 -0.1 0.4 -0.2 0.0 0.2 -0.6 0.1 -0.5 -0.3
Commuting to job workplace: Walk 0.3 0.4 1.4 0.4 -0.5 0.8 0.6 -1.0 0.2 -0.0 -0.6 0.2 -0.3 0.5 1.2 0.2 0.8 0.4
Eye problems/disorders: Cataract 0.4 0.5 1.8 -0.9 -0.8 -0.7 -1.4 -0.2 -0.4 -0.7 0.8 -0.7 -0.4 -0.5 -0.5 -0.5 -0.3 -0.9
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 1.7 -1.0 -1.3 -0.9 -1.3 -1.0 -1.0 -0.7 -0.0 -0.9 -0.9 -0.9 -0.6 -0.9 -0.4 -0.3
Medication for cholesterol 0.3 0.4 2.4 0.3 -0.7 0.8 0.5 -0.2 0.4 0.7 -0.2 0.2 -0.0 0.4 0.5 0.3 0.9 1.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 3.8 4.5 7.1 -2.1 -0.3 -2.4 -1.9 -2.0 -2.7 -2.0 2.1 -2.6 -2.4 -2.6 -1.7 -2.5 -1.4 -1.8
Back pain experienced in last month 0.7 1.0 2.7 -1.0 -1.1 -1.1 -1.2 -1.3 -1.2 -1.7 0.2 -0.7 -0.9 -1.1 -0.3 -1.0 -1.0 -0.5
Mineral and other dietary supplements 1.5 2.0 4.3 1.5 1.2 1.1 1.6 0.9 1.2 1.3 -2.1 1.7 1.0 1.1 1.6 1.0 1.5 1.7
Breast cancer (self-reported) 0.4 0.5 2.3 0.5 -0.1 0.6 0.4 0.2 0.6 0.5 -0.9 1.2 0.4 0.7 0.6 0.6 0.8 1.5
Asthma (self-reported) 0.3 0.5 1.4 0.4 -0.2 1.0 0.7 -0.3 1.0 0.6 -0.8 0.9 0.4 0.9 -0.6 0.7 1.2 0.4
Osteoporosis (self-reported) 0.1 0.2 1.0 -0.2 -1.0 0.1 -0.3 -0.6 0.5 -0.2 -0.5 -0.3 0.0 0.2 -0.2 0.2 0.1 -0.3
Osteoarthritis (self-reported) 0.5 0.6 1.8 1.0 1.3 0.8 1.2 0.5 0.4 0.8 -0.3 0.9 0.4 0.4 0.7 0.3 0.5 1.4
Medication: Aspirin 1.1 1.4 3.8 1.3 1.9 0.9 1.3 1.5 1.0 1.4 -1.0 0.8 1.4 0.9 0.5 1.1 -0.0 1.2
Medication: Gliclazide 0.3 0.3 2.4 -0.2 0.2 -0.5 0.0 0.6 -0.4 -0.3 0.3 -0.5 -0.3 -0.6 -0.5 -0.5 -1.5 -0.6
Illnesses of father: None of the above (group 1) 2.1 2.5 4.8 -1.5 -2.2 -1.5 -1.6 -1.3 -1.6 -1.9 1.7 -1.2 -1.6 -1.5 -0.6 -1.6 -1.5 -2.0
Smoking status: Current 0.9 1.5 3.4 1.2 1.6 1.0 1.6 1.1 1.0 1.2 -0.6 0.7 1.4 1.0 1.8 1.2 0.7 1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 1.2 -0.4 -0.4 -0.4 -0.1 -0.6 -0.6 -1.1 -0.2 -1.0 -0.7 -0.5 -0.5 -0.6 -0.6 -0.5
Whole body water mass 0.6 3.3 14.1 1.7 1.5 1.5 1.8 3.8 1.6 1.4 -1.7 1.9 2.0 1.4 1.2 1.6 0.8 1.6
Leg predicted mass (right) 0.5 2.5 13.3 1.5 1.5 1.3 1.7 3.6 1.2 1.1 -1.5 1.4 1.6 1.1 0.9 1.3 0.5 1.4
Arm fat mass (left) 0.6 2.5 22.5 1.2 1.4 1.0 1.4 4.7 1.1 0.8 -1.0 1.1 1.5 0.8 0.8 1.0 -0.1 0.9
Number of self-reported non-cancer illnesses 0.4 0.7 4.9 0.4 0.3 0.6 0.2 2.2 0.6 0.7 -1.1 0.6 0.7 0.5 1.0 0.6 0.7 0.6
Average weekly champagne plus white wine intake 0.3 0.3 1.8 -0.4 -0.6 -0.4 -0.2 -1.4 -0.5 -0.4 0.1 -0.3 -0.5 -0.4 -0.5 -0.4 -1.1 0.2
Miserableness 1.0 1.8 3.8 1.2 0.5 1.3 0.8 0.2 1.7 1.2 -1.2 1.5 1.6 1.6 1.9 1.6 1.4 1.3
Guilty feelings 0.5 0.7 4.5 0.3 -0.5 0.5 0.2 -2.1 0.8 0.3 -1.0 0.8 0.8 0.8 0.8 0.8 0.7 0.5
Wears glasses or contact lenses 0.2 0.3 0.7 0.6 0.8 0.4 0.6 0.6 0.4 0.7 0.0 0.4 0.8 0.4 0.3 0.6 -0.5 0.4
Ever taken oral contraceptive pill 1.1 1.3 3.0 1.1 1.0 1.4 1.5 1.7 1.3 0.7 -0.0 0.4 1.5 1.5 -0.2 1.6 0.2 0.2
Hearing aid user 0.4 0.4 2.5 -0.1 -0.4 -0.0 -0.4 -0.2 -0.7 -0.4 1.1 -0.7 -0.3 -0.4 -0.6 -0.4 -1.6 -0.6
Mother’s age at death 0.2 0.3 0.8 0.8 0.3 0.3 0.7 0.8 -0.1 0.8 0.6 -0.2 -0.5 -0.1 -0.0 -0.3 0.1 0.9
Financial situation satisfaction 1.2 1.5 3.5 -0.7 -0.8 -0.9 -1.0 -0.6 -1.7 -1.5 0.4 -1.9 -1.7 -1.5 -0.9 -1.6 -1.2 -0.4
Tinnitus: Yes, now most or all of the time 0.3 0.3 2.0 0.4 -0.4 0.3 0.7 1.4 0.4 -0.4 -0.0 0.4 0.4 0.3 0.2 0.3 -1.2 -0.3
Commuting to job workplace: Public transport 0.5 0.6 1.6 0.9 0.5 0.9 0.7 0.1 1.0 0.6 -0.6 0.7 1.2 1.2 -0.1 1.3 -0.1 0.2
Eye problems/disorders: Glaucoma 1.2 1.4 4.3 -0.8 -0.8 -1.0 -0.8 -1.2 -1.1 -1.5 0.3 -0.7 -1.2 -1.0 -1.4 -1.1 -2.1 -1.5
Medication: Blood pressure 0.7 1.4 7.1 1.6 2.7 0.9 1.4 1.1 0.9 0.8 -0.6 1.0 1.3 0.9 0.9 1.0 -0.4 -0.0
Pain type(s) experienced in last month: Hip pain 1.1 1.4 3.5 1.2 1.0 1.4 1.0 1.1 0.8 1.1 -0.7 1.5 0.6 1.1 1.2 0.9 1.9 1.6
Supplements: Fish oil (including cod liver oil) 0.8 1.1 3.2 -1.3 -0.9 -0.9 -1.4 -0.4 -0.8 -1.1 1.8 -1.4 -0.6 -0.7 -0.7 -0.7 -0.4 -1.1
High cholesterol (Self-reported) 0.6 1.1 2.3 -1.1 -1.3 -1.4 -1.5 -0.1 -1.0 -1.1 0.0 -0.9 -0.8 -1.1 -0.7 -1.0 -1.0 -1.3
Medication: Bendroflumethiazide 1.2 1.8 4.9 1.9 2.2 1.5 1.6 1.3 1.2 1.0 -1.3 1.0 1.2 1.3 0.5 1.2 0.6 1.0
Medication: Paracetamol 0.1 0.2 0.9 -0.5 -0.9 -0.7 -0.6 0.3 -0.4 -0.7 -0.3 0.0 -0.3 -0.4 -0.4 -0.3 0.1 0.3
Medication: Lisinopril 0.2 0.3 1.9 0.1 -0.3 0.0 -0.3 1.4 0.5 -0.1 -0.9 0.1 0.6 0.4 -0.6 0.4 0.3 -0.2
Medication: Atorvastatin 0.1 0.1 0.7 -0.3 -0.4 -0.4 -0.3 -0.9 -0.3 -0.1 0.3 -0.3 -0.2 -0.4 -0.4 -0.3 -0.1 -0.1
Illnesses of father: High blood pressure 0.4 0.5 2.5 0.4 1.1 0.7 0.5 1.6 0.7 0.3 -0.3 -0.1 0.6 0.6 -0.9 0.6 0.2 0.6
Alcohol drinker status: Never 0.1 0.1 0.4 0.1 0.5 -0.2 0.1 0.2 -0.3 -0.1 0.6 0.2 -0.1 -0.2 0.3 -0.2 0.1 0.4
Ever smoked 1.1 1.9 5.2 2.0 2.2 1.5 2.3 0.7 1.0 1.0 -1.2 1.1 1.4 1.2 0.6 1.2 -0.4 1.5
Basal metabolic rate 0.6 3.3 16.9 1.6 1.6 1.4 1.8 4.1 1.5 1.4 -1.6 1.8 2.0 1.3 1.2 1.6 0.6 1.5
Leg fat percentage (left) 0.4 1.4 16.1 0.4 1.2 0.2 0.4 4.0 0.6 0.5 0.1 0.6 1.2 0.2 0.6 0.6 -0.4 0.1
Arm fat-free mass (left) 0.3 1.4 9.5 0.9 1.1 0.7 1.1 3.1 0.8 0.6 -1.0 1.2 1.3 0.7 0.9 0.9 0.3 0.8
Number of operations (self-reported) 1.2 1.8 3.6 -1.5 -0.1 -1.7 -1.4 -0.4 -1.9 -0.7 1.2 -1.8 -1.5 -1.9 0.6 -1.8 -0.1 -1.0
Average weekly beer plus cider intake 0.3 0.4 1.9 -0.8 -1.4 -0.4 -0.4 -0.3 -0.1 -1.0 0.2 -0.7 -0.2 -0.4 -0.4 -0.3 -0.0 -1.0
Irritability 0.4 0.6 1.6 0.8 -0.2 0.8 0.8 -0.2 1.1 0.5 -0.4 0.9 0.8 1.0 1.0 0.9 0.5 1.2
Risk taking 0.1 0.1 0.7 -0.1 -0.2 -0.3 -0.1 0.8 0.0 -0.0 0.5 -0.1 0.1 -0.1 0.3 -0.0 0.2 0.1
Ever had prostate specific antigen (PSA) test 0.4 0.5 4.3 0.4 2.1 0.4 0.3 0.6 0.2 0.3 0.5 -0.0 0.3 0.2 -0.0 0.2 -1.2 -0.5
Fractured/broken bones in last 5 years 0.3 0.3 1.5 0.2 0.4 0.3 0.2 0.3 0.4 1.1 -0.1 0.5 0.5 0.5 1.2 0.5 0.7 0.4
Age started oral contraceptive pill 3.9 4.9 9.3 -2.7 -2.4 -2.2 -2.9 -0.3 -2.0 -2.2 2.3 -2.1 -1.9 -2.0 -2.0 -1.9 -1.9 -3.0
Diastolic blood pressure, automated reading 5.4 16.7 23.8 3.9 3.9 4.2 3.9 4.9 4.2 4.8 -3.0 3.7 4.3 4.0 3.7 4.2 4.1 4.2
Ever depressed for a whole week 4.2 5.1 9.5 -2.7 -1.9 -2.6 -2.4 1.3 -2.1 -1.7 3.1 -1.9 -1.8 -2.2 -2.4 -2.0 -2.8 -2.4
Unable to work because of sickness or disability 0.5 0.6 1.7 -1.0 -0.1 -1.3 -1.1 0.3 -1.0 -0.4 0.9 -0.4 0.3 -0.9 0.3 -0.4 -1.0 -1.0
Commuting to job workplace: Cycle 0.2 0.2 1.7 0.0 -0.5 0.2 0.0 -1.3 -0.3 -0.1 -0.5 -0.1 -0.5 0.0 -0.3 -0.2 -0.3 0.5
Myopia 0.6 0.9 2.7 1.1 0.7 1.0 0.6 0.2 1.1 0.9 -1.6 0.9 1.1 1.2 0.4 1.2 0.1 0.6
Vascular/heart problems diagnosed by doctor 3.1 8.4 16.6 -2.9 -3.6 -2.9 -2.7 -4.1 -3.0 -2.6 2.4 -3.0 -3.2 -2.9 -2.6 -3.0 -1.5 -2.2
Cholesterol lowering medication 0.3 0.5 2.5 0.2 1.1 0.3 0.2 1.6 0.4 0.3 -0.1 1.0 0.7 0.4 -0.4 0.5 0.3 -0.9
Medication: Omeprazole (e.g. Zanprol) 2.4 2.9 6.0 2.1 2.4 1.2 2.0 1.9 1.2 1.5 -1.3 1.9 1.9 1.2 2.1 1.4 0.5 1.8
Pain experienced in last month 0.3 0.5 1.2 1.0 0.9 0.7 1.1 -0.5 0.5 0.7 -0.1 0.5 0.9 0.7 -0.3 0.8 -0.8 -0.5
Supplements: Calcium 0.2 0.2 0.6 0.5 0.2 0.5 0.4 -0.3 0.5 -0.0 0.7 -0.2 -0.0 0.4 -0.8 0.2 0.4 0.5
Basal cell carcinoma (self-reported) 0.3 0.3 0.9 -0.2 -0.9 0.5 -0.2 0.1 0.8 0.1 -0.3 0.0 0.9 0.8 0.4 0.8 0.5 0.3
Heart attack/myocardial infarction (self-reported) 1.5 1.9 2.8 1.2 1.3 1.4 0.9 0.7 1.7 1.2 -1.4 1.5 1.6 1.5 1.1 1.6 1.6 1.6
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 2.6 0.3 0.5 -0.2 0.4 -0.3 -0.2 0.7 -0.8 -0.3 0.1 -0.4 1.6 -0.2 1.1 0.3
Heart disease (siblings) 1.0 1.2 2.6 -1.3 -1.6 -1.1 -1.3 0.2 -0.9 -0.9 1.1 -1.2 -1.0 -1.0 -1.2 -1.0 -1.0 -0.7
Alcohol drinker status: Previous 0.2 0.3 2.3 -0.4 -0.0 -0.3 -0.6 -0.1 0.3 0.5 -0.3 0.2 0.3 0.1 0.5 0.2 1.5 0.1
Pack years of smoking 0.6 0.8 2.6 -1.1 -1.0 -0.6 -1.2 1.6 -0.6 -0.9 0.5 -0.5 -0.8 -0.8 -0.6 -0.8 -0.5 -1.3
Impedance of whole body 0.5 2.5 8.2 -1.5 -2.1 -1.5 -2.0 -2.9 -1.1 -1.2 1.1 -1.9 -1.3 -1.1 -1.6 -1.2 -0.7 -1.3
Leg fat mass (left) 0.6 2.2 21.5 0.9 1.4 0.7 1.0 4.6 0.9 0.7 -0.6 1.0 1.5 0.6 0.7 0.9 -0.2 0.6
Arm predicted mass (left) 0.3 1.6 10.4 1.0 1.2 0.8 1.2 3.2 0.9 0.8 -0.9 1.4 1.3 0.7 1.0 0.9 0.4 0.9