TWAS hub - SATB1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.087	0.0390	0.0098	-0.001	NA	0.018	NA	0.006	3.9e-01	NA	0.011	NA	0.0940
2	GTEx	Heart Left Ventricle	0.123	0.0496	0.0048	0.104	NA	0.026	NA	0.049	3.5e-06	NA	0.015	NA	0.0013

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Commuting to job workplace: Cycle	7.6	9.1	10.9	-2.7	-3.3
Schizophrenia vs Biploar Disorder	6.6	8.7	9.1	-2.9	-3.0
Medication: Ventolin 100micrograms inhaler	5.0	6.4	6.9	2.6	2.4
Medication: Paracetamol	4.4	7.2	14.3	-3.8	0.3
Supplements: Fish oil (including cod liver oil)	4.2	5.5	9.4	1.3	3.1
Supplements: Calcium	4.2	4.6	5.7	1.9	2.4
Pain type(s) experienced in last month: Hip pain	4.0	5.0	8.1	2.9	1.4
Wears glasses or contact lenses	3.7	4.2	6.7	2.6	1.3
Coronary Artery Disease (CAD)	3.5	4.2	6.4	-2.5	-1.4
Illnesses of mother	3.5	4.4	6.4	-1.5	-2.5
Qualifications: nursing, teaching	3.5	5.5	8.6	1.6	2.9
Mouth/teeth dental problems	3.4	5.2	6.9	2.6	1.9
Pulse wave Arterial Stiffness index	3.4	4.0	4.6	2.1	1.8
Medication: Seretide 50 evohaler	3.4	3.9	6.5	2.6	1.1
Mineral and other dietary supplements	3.4	4.5	8.0	-1.1	-2.8
Alcohol drinker status: Never	3.2	3.8	4.2	-2.0	-1.8
Alzheimer’s Disease (in father)	3.1	3.3	5.1	1.2	2.3
Long-standing illness, disability or infirmity	3.1	4.7	8.3	2.9	1.0
Handedness (chirality/laterality): Left-handed	3.0	3.7	6.4	-2.5	-1.0
Length of working week for main job	2.9	3.2	6.2	2.5	0.4
Medication: Ibuprofen	2.9	3.5	7.0	0.1	2.6
Illness, injury, bereavement, stress in last 2 years	2.9	3.5	4.5	-2.1	-1.6
Ever depressed for a whole week	2.9	3.6	5.9	-2.4	-1.1
Number of full brothers	2.8	3.5	5.7	1.1	2.4
Age when periods started (menarche)	2.6	6.3	11.2	-1.2	-3.3
Peak expiratory flow (PEF)	2.6	6.0	7.7	2.8	2.1
Pack years of smoking	2.6	3.9	6.0	2.4	1.3
Had other major operations	2.5	3.1	5.6	2.4	0.7
Age at First Birth	2.4	3.4	6.7	-2.6	0.4
Pulse rate, automated reading	2.4	7.7	14.6	3.8	-0.9
Chronotype (morning person)	2.3	5.3	10.6	3.2	0.2
Sensitivity / hurt feelings	2.3	4.0	5.5	2.3	1.6
Supplements: Zinc	2.3	2.5	4.7	-2.2	-0.6
Diverticular disease/diverticulitis (self-reported)	2.3	2.8	4.4	-2.1	-1.1
Pulse wave peak to peak time	2.3	2.7	3.0	-1.7	-1.5
Medication: Paracetamol	2.3	3.5	6.5	-2.6	0.7
Body Mass Index (BMI) (2010)	2.2	3.0	4.4	-2.1	-1.3
Blood Platelet Count	2.2	25.0	30.6	-5.5	-4.4
Medication for pain relief, constipation, heartburn	2.2	3.8	6.0	2.4	-1.2
Illnesses of siblings: Diabetes	2.2	2.7	2.9	1.6	1.7
Mean Putamen Volume	2.1	2.3	4.0	-0.8	-2.0
Pack years adult smoking proportion	2.1	3.2	5.0	2.2	1.2
Illnesses of siblings	2.1	2.9	5.5	-0.5	-2.3
Time employed in main current job	2.1	2.4	3.2	-1.8	-1.2
Medication: Ibuprofen (e.g. Nurofen)	2.1	2.7	4.0	-1.1	2.0
Mouth/teeth dental problems: Loose teeth	2.1	2.5	4.2	-0.9	-2.0
Crohns Disease (2012)	2.0	3.3	3.6	-1.9	-1.7
LDL Cholesterol	2.0	3.2	4.9	-1.2	-2.2
Other serious medical condition/disability diagnosed by doctor	2.0	2.6	5.1	2.3	0.1
Ever unenthusiastic/disinterested for a whole week	2.0	2.4	3.6	-1.9	-1.1
Type 2 Diabetes (T2D) (2012)	1.9	2.2	2.2	1.5	-1.5
Schizophrenia (2018)	1.8	3.6	3.7	-1.9	-1.9
Pain all over the body in last month	1.8	1.9	2.4	-1.2	-1.5
Medication: Cholesterol lowering	1.8	2.9	5.6	2.4	0.4
Qualifications: O levels/GCSEs or equivalent	1.8	2.9	4.4	1.2	2.1
Medication for cholesterol, blood pressure or diabetes	1.8	3.0	5.9	-2.4	-0.3
Age at first live birth	1.8	3.2	6.3	-2.5	0.0
HDL Cholesterol	1.7	2.8	3.8	-1.4	-1.9
Serious illness, injury or assault to yourself	1.7	2.0	3.4	1.8	0.8
Father’s age at death	1.7	2.3	4.6	2.1	0.3
Pain experienced in last month	1.7	2.8	5.0	2.2	0.8
Hypothyroidism (self reported)	1.6	3.6	6.3	-2.5	-0.9
Bilateral oophorectomy (both ovaries removed)	1.6	1.8	3.6	1.9	0.0
Had menopause	1.6	2.0	2.4	1.3	1.6
High blood pressure (siblings)	1.6	2.3	3.8	0.9	2.0
Medication: Blood pressure	1.6	2.9	5.2	2.3	0.7
Knee pain experienced in last month	1.6	2.5	4.7	-2.2	0.5
Ever smoked	1.6	2.7	2.9	1.7	1.6
Number of operations (self-reported)	1.6	2.4	4.3	2.1	-0.7
Medication: Omeprazole	1.5	1.8	3.6	0.2	-1.9
Age at last live birth	1.5	2.1	4.2	-2.1	-0.3
Schizophrenia (2014)	1.4	3.1	3.2	-1.8	-1.7
High blood pressure (mother)	1.4	1.9	2.5	-1.2	1.6
Serious illness, injury or assault of a close relative in last 2 years	1.4	1.7	1.9	1.2	1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.6	3.2	0.3	-1.8
Eye problems/disorders: Glaucoma	1.4	1.7	2.0	1.4	-1.2
Nervous feelings	1.3	2.4	4.1	2.0	0.8
Glaucoma (self-reported)	1.3	1.5	1.5	1.2	-1.2
Chronic bronchitis/emphysema (mother)	1.3	1.6	1.8	1.2	1.3
Illnesses of father: Heart disease	1.3	1.8	1.8	1.3	-1.4
Unable to work because of sickness or disability	1.3	1.7	3.2	-0.4	-1.8
Ulcerative Colitis (UC)	1.2	2.2	3.3	1.8	1.0
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	2.5	-1.6	-0.3
Medication: Metformin	1.2	1.7	3.3	1.8	0.3
Past tobacco smoking	1.2	2.2	2.8	-1.7	-1.3
Medication: Amlodipine	1.2	1.7	3.3	1.8	0.3
Smoking status: Previous	1.2	1.7	2.5	1.6	1.0
Commuting to job workplace: Walk	1.2	1.3	1.5	-1.2	-1.1
Number of self-reported non-cancer illnesses	1.2	2.1	4.2	2.0	0.3
Average weekly beer plus cider intake	1.2	1.8	3.5	-1.9	-0.2
Neuroticism (Nagel 2018)	1.1	2.6	4.9	2.2	0.6
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	3.6	1.9	0.2
Number of live births	1.1	1.6	2.3	1.5	0.9
Medication: Lansoprazole	1.1	1.3	1.7	1.0	1.3
Leg pain on walking	1.1	1.3	2.1	-0.8	1.4
Type 2 Diabetes (T2D) (2018)	1.0	1.8	3.5	1.9	-0.3
Vitamin and mineral supplements	1.0	1.4	2.7	0.3	-1.6
Gout (self-reported)	1.0	1.4	2.8	-1.7	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.0	1.2	1.9	1.4	-0.6
Had major operations	1.0	1.2	2.4	1.5	-0.3
Medication: Aspirin	1.0	1.3	2.0	0.8	1.4
High cholesterol (Self-reported)	1.0	1.8	3.4	1.9	-0.5
Medication: Bendroflumethiazide	1.0	1.5	1.7	1.3	1.2
Vascular/heart problems diagnosed by doctor	1.0	2.6	3.9	-2.0	-1.1
Primary Biliary Cirrhosis	0.9	1.3	1.9	-0.9	-1.4
Allergy or Eczema	0.9	2.3	4.4	-0.4	-2.1
Severe depression (siblings)	0.9	1.1	1.2	0.9	1.1
Average weekly fortified wine intake	0.9	1.1	2.2	0.0	1.5
High blood pressure	0.9	2.6	3.4	1.9	1.3
Supplements: Glucosamine	0.9	1.2	2.2	-0.5	1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	2.3	1.5	-0.4
Eye problems/disorders: None of the above	0.9	1.1	1.8	-1.3	0.6
Overall health rating	0.9	1.9	3.5	1.9	0.5
Commuting to job workplace: Car/motor vehicle	0.9	1.0	1.8	0.5	1.3
Osteoarthritis (self-reported)	0.9	1.1	1.6	1.3	0.8
Depression (Nagel 2018)	0.8	1.1	1.8	0.7	-1.4
Diabetes (father)	0.8	1.0	1.3	-0.9	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	1.6	-0.7	-1.3
Stomach or abdominal pain in last month	0.8	1.0	1.4	-1.2	-0.7
Hair/balding pattern: Pattern 2	0.8	1.1	1.7	-0.7	-1.3
Qualifications: None of the above	0.8	1.8	3.5	-0.3	-1.9
Hayfever/allergic rhinitis (self-reported)	0.8	1.0	1.7	0.6	-1.3
Falls in the last year	0.8	1.1	2.0	1.4	-0.3
Breastfed as a baby	0.8	0.9	1.5	0.7	1.2
Medication: Aspirin	0.8	1.1	1.5	0.8	1.2
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	1.7	-0.4	-1.3
Heart disease (siblings)	0.8	1.0	1.0	-1.0	1.0
Intelligence (Savage-Jansen 2018)	0.7	2.2	3.7	0.8	1.9
Lupus	0.7	1.1	2.0	-1.4	-0.4
Blood White Count	0.7	5.2	7.5	2.7	1.7
Respiratory disease	0.7	1.5	1.5	1.2	-1.2
Average weekly spirits intake	0.7	0.9	1.8	-0.1	1.4
Ever used hormone-replacement therapy (HRT)	0.7	0.8	1.4	1.2	-0.5
Diabetes (mother)	0.7	0.9	0.9	1.0	0.9
Hayfever, allergic rhinitis or eczema	0.7	1.4	2.8	-0.3	-1.7
Financial difficulties in last 2 years	0.7	1.0	1.2	1.1	0.8
Medication: Simvastatin	0.7	1.0	1.9	1.4	-0.2
Neuroticism score	0.7	1.4	2.2	1.5	0.8
Hair/balding pattern: Pattern 3	0.7	1.1	1.4	0.8	1.2
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	2.5	-1.6	0.5
Shortness of breath walking on level ground	0.7	0.9	1.7	0.2	1.3
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.8	1.6	1.3	0.1
Asthma (self-reported)	0.7	1.5	2.5	1.6	0.7
Tinnitus: Yes, now most or all of the time	0.7	0.9	1.7	1.3	-0.1
Medication: Lisinopril	0.7	1.0	1.7	1.3	-0.5
Leg fat percentage (left)	0.7	2.4	4.8	-0.2	2.2
Basal cell carcinoma (self-reported)	0.7	0.8	1.5	-1.2	-0.0
Leg fat mass (left)	0.7	2.6	5.2	0.1	2.3
Bipolar Disorder (2018)	0.6	1.0	1.7	0.5	1.3
Ovarian Cancer	0.6	0.8	1.6	1.3	0.3
Prostate Cancer	0.6	0.9	1.0	-0.9	-1.0
HbA1C	0.6	0.7	1.1	-1.0	-0.5
Neuroticism	0.6	1.6	2.8	1.7	0.5
Number of treatments/medications taken	0.6	1.1	1.6	1.3	0.8
Chronic bronchitis/emphysema (father)	0.6	0.7	1.3	1.1	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.6	1.0	1.9	1.4	-0.3
Arm fat percentage (right)	0.6	2.2	4.3	-0.4	2.1
Happiness	0.6	0.8	1.5	0.2	-1.2
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	1.3	-0.5	-1.1
Body fat percentage	0.6	2.5	4.8	-0.4	2.2
Leg fat percentage (right)	0.6	2.2	4.3	-0.0	2.1
Emphysema/chronic bronchitis	0.6	0.7	1.0	0.6	-1.0
Leg fat mass (right)	0.6	2.4	4.8	0.1	2.2
Suffer from ‘nerves’	0.6	0.9	1.7	1.3	-0.3
Arm fat percentage (left)	0.6	2.2	4.3	-0.3	2.1
Loneliness, isolation	0.6	0.9	1.7	-0.1	-1.3
Ever had bowel cancer screening	0.6	0.7	1.1	1.1	0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	0.8	0.9	-0.7
Hearing aid user	0.6	0.6	1.0	-0.5	1.0
Medication: Atorvastatin	0.6	0.8	1.6	1.3	-0.0
Ever had prostate specific antigen (PSA) test	0.6	0.6	1.2	0.3	-1.1
Fractured/broken bones in last 5 years	0.6	0.7	0.8	-0.9	-0.8
Depressed Affect (Nagel 2018)	0.5	1.0	1.5	1.2	0.7
Worry (Nagel 2018)	0.5	1.0	2.1	1.4	0.0
Major Depression (MDD)	0.5	0.6	0.6	-0.7	-0.8
Reaction Time	0.5	0.9	1.8	-0.2	-1.4
Verbal and Numeric Reasoning (VNR)	0.5	1.1	2.2	0.2	1.5
Rheumatoid Arthritis	0.5	0.7	1.4	-1.2	-0.1
Triglycerides	0.5	0.8	1.5	-0.3	1.2
Ulcerative Colitis	0.5	0.8	1.0	1.0	0.8
Relative age of first facial hair	0.5	1.0	1.9	1.4	0.2
Ever had hysterectomy (womb removed)	0.5	0.6	1.1	-0.3	-1.0
Systolic blood pressure, automated reading	0.5	1.3	2.0	0.8	1.4
Trunk fat percentage	0.5	2.1	4.0	-0.4	2.0
Medication: Levothyroxine sodium	0.5	0.8	1.6	-1.3	0.1
Trunk fat mass	0.5	2.2	4.3	-0.1	2.1
Qualifications: A levels/AS levels or equivalent	0.5	1.1	1.6	1.3	0.7
Asthma	0.5	1.1	1.7	1.3	0.6
Loud music exposure frequency	0.5	0.5	1.0	-1.0	-0.1
Exposure to tobacco smoke outside home	0.5	0.7	1.0	1.0	0.6
Wheeze or whistling in the chest in last year	0.5	0.9	1.4	1.2	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	0.8	-0.9	-0.5
Mean time to correctly identify matches	0.5	0.9	1.8	0.2	-1.4
Whole body fat mass	0.5	2.3	4.6	-0.1	2.1
Chest pain or discomfort	0.5	0.7	1.3	1.2	-0.2
Diabetes diagnosed by doctor	0.5	0.8	1.0	1.0	-0.7
Arm fat mass (left)	0.5	2.3	4.5	-0.1	2.1
Bipolar Disorder or Schizophrenia	0.4	0.9	1.3	-1.1	-0.7
Alzheimer’s Disease (in mother)	0.4	0.5	0.6	0.8	-0.6
Breast Cancer	0.4	1.0	1.4	1.2	0.8
Smoking Status	0.4	1.1	2.0	1.4	0.4
Taking other prescription medications	0.4	0.6	0.7	0.8	0.7
Multivitamins +/- minerals	0.4	0.6	1.0	0.3	1.0
Noisy workplace	0.4	0.5	1.0	0.2	1.0
Depression (self-reported)	0.4	0.5	0.7	-0.6	-0.8
Prospective memory result	0.4	0.5	1.0	0.3	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.4	2.5	1.6	0.6
Arm fat mass (right)	0.4	1.7	3.2	-0.4	1.8
Ever highly irritable/argumentative for 2 days	0.4	0.5	0.9	0.0	-1.0
Blood clot in the leg (DVT)	0.4	0.5	0.6	0.8	0.6
Forced vital capacity (FVC), Best measure	0.4	1.4	2.6	1.6	0.5
Medication: Allopurinol	0.4	0.6	1.1	-1.1	0.2
Alcohol intake frequency.	0.4	0.9	1.3	1.2	-0.6
Hypertension (Self-reported)	0.4	1.1	1.6	1.3	0.8
Medication: Gliclazide	0.4	0.4	0.9	-0.1	0.9
Illnesses of father: High blood pressure	0.4	0.4	0.9	0.0	0.9
Risk taking	0.4	0.5	0.8	-0.5	-0.9
Myopia	0.4	0.6	0.8	0.9	0.7
Fasting Glucose	0.3	0.3	0.7	0.1	-0.8
Blood Eosinophil Count	0.3	1.9	3.9	0.0	-2.0
Waist Hip Ratio (WHR)	0.3	1.3	2.7	-0.0	1.6
Lung FVC	0.3	1.4	2.8	1.7	-0.3
Hand grip strength (right)	0.3	0.7	0.8	-0.8	-0.9
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.4	0.6	-0.5
Medication: Atenolol	0.3	0.4	0.7	-0.1	-0.9
Body mass index (BMI)	0.3	1.4	2.8	0.2	1.7
Impedance of leg (left)	0.3	1.4	2.4	-1.5	-0.6
Waist circumference	0.3	1.2	2.4	0.2	1.5
Alcohol usually taken with meals	0.3	0.4	0.6	0.7	0.5
Weight	0.3	1.3	2.5	0.3	1.6
Impedance of arm (right)	0.3	1.4	2.2	-1.5	-0.7
Worrier / anxious feelings	0.3	0.6	1.0	1.0	0.4
Mouth/teeth dental problems: Dentures	0.3	0.5	1.0	-1.0	0.2
Headache pain in last month	0.3	0.5	0.5	-0.6	-0.7
Qualifications: College or University degree	0.3	0.9	1.2	0.8	1.1
Heart disease (mother)	0.3	0.3	0.4	-0.7	0.5
Family relationship satisfaction	0.3	0.3	0.5	-0.7	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	0.8	-0.9	0.2
Illnesses of father: None of the above (group 1)	0.3	0.4	0.5	-0.4	-0.7
Miserableness	0.3	0.5	0.6	0.7	0.6
Irritability	0.3	0.5	0.9	-1.0	0.3
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.5	0.7	0.6
Impedance of whole body	0.3	1.4	2.5	-1.6	-0.5
Arm predicted mass (left)	0.3	1.3	2.2	0.6	1.5
Alzheimer’s Disease (including proxy)	0.2	0.2	0.4	0.6	0.3
Irritable Bowel Disease (IBD)	0.2	0.5	0.6	0.8	0.6
BMI	0.2	1.3	2.4	-1.6	0.5
Hand grip strength (left)	0.2	0.6	1.2	-1.1	-0.3
Hearing difficulty/problems: Yes	0.2	0.3	0.7	0.0	-0.8
Medication for hormone replacement therapy	0.2	0.2	0.5	0.7	-0.1
Impedance of leg (right)	0.2	0.9	1.4	-1.2	-0.7
Leg fat-free mass (left)	0.2	1.2	1.9	0.7	1.4
Townsend deprivation index at recruitment	0.2	0.2	0.4	-0.2	-0.6
Current tobacco smoking	0.2	0.4	0.7	0.3	0.9
Maternal smoking around birth	0.2	0.3	0.5	0.7	0.1
Fed-up feelings	0.2	0.4	0.8	0.9	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.3	0.6	0.8	0.2
Leg predicted mass (left)	0.2	1.1	1.8	0.6	1.4
Number of incorrect matches in round	0.2	0.3	0.4	0.3	-0.6
Medication: Ramipril	0.2	0.3	0.5	-0.2	0.7
Trunk fat-free mass	0.2	1.2	1.4	1.0	1.2
Hip circumference	0.2	0.7	1.3	0.4	1.1
Pulse rate	0.2	0.3	0.6	0.2	-0.8
Impedance of arm (left)	0.2	0.7	1.3	-1.2	-0.3
Trunk predicted mass	0.2	1.3	1.4	1.1	1.2
Tense / ‘highly strung’	0.2	0.4	0.6	0.8	-0.4
Arm predicted mass (right)	0.2	0.8	1.3	0.6	1.1
Comparative height size at age 10	0.2	0.9	1.5	-1.2	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.2	0.4	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	0.7	-0.8	-0.1
Whole body fat-free mass	0.2	1.0	1.4	0.8	1.2
Leg fat-free mass (right)	0.2	0.8	1.4	0.5	1.2
Average weekly red wine intake	0.2	0.3	0.6	-0.2	0.8
Whole body water mass	0.2	0.9	1.4	0.7	1.2
Leg predicted mass (right)	0.2	0.8	1.5	0.4	1.2
Average weekly champagne plus white wine intake	0.2	0.3	0.3	-0.5	-0.5
Mother’s age at death	0.2	0.2	0.4	0.6	-0.3
Financial situation satisfaction	0.2	0.3	0.6	-0.8	0.0
Commuting to job workplace: Public transport	0.2	0.3	0.3	-0.6	0.4
Basal metabolic rate	0.2	1.0	1.6	0.5	1.3
Arm fat-free mass (left)	0.2	0.8	1.5	0.5	1.2
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.4	-0.6	-0.2
Crohns Disease (2017)	0.1	0.2	0.3	-0.6	-0.4
Bipolar Disorder (2011)	0.1	0.1	0.1	0.0	0.4
Neuroticism (2016)	0.1	0.1	0.2	0.5	-0.3
Systolic Blood Pressure	0.1	0.5	1.1	0.0	1.0
Lung FEV1/FVC ratio	0.1	0.6	1.0	1.0	0.3
Tanning	0.1	1.7	2.5	-1.6	-0.9
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.2	0.5	-0.4
Relative age voice broke	0.1	0.2	0.3	0.6	0.1
Qualifications: CSEs or equivalent	0.1	0.1	0.2	-0.4	0.0
Hearing difficulty/problems with background noise	0.1	0.2	0.2	0.4	-0.5
Heart attack	0.1	0.1	0.1	-0.3	0.3
Allergy	0.1	0.3	0.6	-0.8	0.3
Diabetes (self-reported)	0.1	0.2	0.2	0.5	-0.5
Fluid intelligence score	0.1	0.3	0.5	-0.7	0.2
Lung cancer (father)	0.1	0.1	0.1	-0.3	-0.2
Birth weight of first child	0.1	0.3	0.5	0.7	-0.1
Pulse wave reflection index	0.1	0.1	0.2	0.1	0.5
Arm fat-free mass (right)	0.1	0.5	0.9	0.3	0.9
Worry too long after embarrassment	0.1	0.2	0.3	0.5	-0.2
Health satisfaction	0.1	0.1	0.2	0.1	-0.5
Migraine (self-reported)	0.1	0.1	0.1	0.4	0.3
Number of full sisters	0.1	0.1	0.1	0.4	-0.0
Mood swings	0.1	0.1	0.2	0.1	-0.4
Friendships satisfaction	0.1	0.1	0.2	0.5	0.1
Back pain experienced in last month	0.1	0.2	0.3	-0.6	-0.2
Breast cancer (self-reported)	0.1	0.1	0.1	0.3	0.1
Osteoporosis (self-reported)	0.1	0.1	0.1	-0.1	-0.4
Smoking status: Current	0.1	0.2	0.4	-0.0	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	0.2	0.4	0.4
Ever taken oral contraceptive pill	0.1	0.1	0.2	0.4	-0.1
Age started oral contraceptive pill	0.1	0.2	0.3	0.0	-0.6
Cholesterol lowering medication	0.1	0.1	0.3	0.0	-0.5
Alcohol drinker status: Previous	0.1	0.1	0.1	0.0	-0.4
Blood Red Count	0.0	0.4	0.7	0.9	0.3
Heel T-Score	0.0	0.2	0.3	-0.6	0.1
Height	0.0	0.4	0.6	0.3	0.8
Cardiovascular Disease	0.0	0.0	0.1	-0.2	0.1
Hair Pigment	0.0	1.2	1.2	-1.1	-1.1
Angina	0.0	0.0	0.0	0.1	-0.1
Medication: Co-codamol	0.0	0.0	0.0	0.1	-0.1
Sitting height	0.0	0.2	0.3	0.5	-0.1
Forced vital capacity (FVC)	0.0	0.1	0.2	0.5	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.0	0.1	0.1	0.2	-0.3
Alcohol intake versus 10 years previously	0.0	0.1	0.1	0.3	-0.2
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.2	0.5	0.2
Standing height	0.0	0.1	0.1	0.3	0.1
Exposure to tobacco smoke at home	0.0	0.1	0.1	-0.3	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.0	0.0	-0.0	-0.1
Hair/balding pattern: Pattern 4	0.0	0.1	0.1	0.1	-0.3
Birth weight	0.0	0.0	0.0	0.0	-0.0
Comparative body size at age 10	0.0	0.1	0.2	-0.4	-0.0
Number of children fathered	0.0	0.1	0.1	-0.2	-0.3
Neck or shoulder pain in last month	0.0	0.0	0.0	0.1	0.1
Angina (self-reported)	0.0	0.0	0.0	-0.0	0.0
Supplements: Vitamin C	0.0	0.0	0.1	0.3	0.0
Eye problems/disorders: Cataract	0.0	0.0	0.0	-0.2	-0.0
Medication for cholesterol	0.0	0.1	0.1	-0.4	-0.0
Guilty feelings	0.0	0.0	0.1	-0.1	0.2
Medication: Blood pressure	0.0	0.0	0.1	0.2	0.1
Diastolic blood pressure, automated reading	0.0	0.0	0.1	0.3	0.1

Hub : Genes

SATB1

Models

Trait associations