TWAS hub - SCAND1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Caudate basal ganglia	0.261	0.1000	3.8e-03	-0.002	NA	0.023	NA	0.004	3.7e-01	NA	7.0e-02	NA	2.4e-01
2	ROSMAP	Brain Pre-frontal Cortex	0.051	0.0206	3.3e-07	0.075	0.056	0.069	0.06	0.071	7.3e-10	1.1e-07	3.6e-09	3.4e-08	1.7e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Arm fat-free mass (right)	13.4	68.8	136.9	-0.9	-11.7
Trunk fat-free mass	13.2	75.7	151.3	0.2	-12.3
Trunk predicted mass	13.2	75.7	151.3	0.2	-12.3
Arm predicted mass (right)	13.0	66.6	132.5	-0.8	-11.5
Whole body water mass	12.8	73.2	146.4	0.0	-12.1
Whole body fat-free mass	12.6	72.0	144.0	0.1	-12.0
Sitting height	12.3	87.5	156.2	4.3	-12.5
Arm fat-free mass (left)	11.9	60.2	120.2	-0.5	-11.0
Arm predicted mass (left)	11.9	60.7	121.0	-0.7	-11.0
Leg fat-free mass (right)	11.5	61.6	123.2	0.1	-11.1
Leg predicted mass (right)	11.5	61.6	123.2	0.1	-11.1
Basal metabolic rate	11.5	63.8	127.7	-0.1	-11.3
Height	10.8	207.4	400.0	3.8	-20.0
Leg fat-free mass (left)	10.8	57.3	114.5	0.4	-10.7
Leg predicted mass (left)	10.6	56.3	112.4	0.4	-10.6
Standing height	10.5	103.7	197.5	3.1	-14.1
Comparative height size at age 10	6.9	38.0	74.8	1.1	-8.7
Weight	6.6	32.6	65.2	-0.3	-8.1
Tanning	6.5	79.7	98.0	-9.9	-7.8
Breast cancer (self-reported)	5.1	6.1	7.4	-2.7	-2.2
Ovarian Cancer	4.7	6.2	9.4	1.7	3.1
Impedance of arm (right)	4.7	21.8	31.8	3.4	5.6
Medication: Simvastatin	4.4	6.4	8.0	2.2	2.8
Impedance of leg (right)	4.3	20.9	40.7	1.0	6.4
Deep venous thrombosis (DVT) (self-reported)	4.2	5.4	7.8	-1.7	-2.8
Other serious medical condition/disability diagnosed by doctor	4.1	5.3	7.8	-2.8	-1.7
Impedance of whole body	4.1	20.6	35.4	2.4	6.0
Time employed in main current job	3.9	4.5	7.8	1.1	2.8
Hypothyroidism (self reported)	3.8	8.7	12.6	-3.6	-2.2
Respiratory disease	3.8	8.5	14.5	-1.6	-3.8
Impedance of leg (left)	3.8	18.3	36.3	0.6	6.0
Blood clot in the leg (DVT)	3.8	4.9	7.3	-1.6	-2.7
Mood swings	3.8	6.9	12.8	-1.0	-3.6
Hip circumference	3.7	16.1	31.9	-0.6	-5.7
Impedance of arm (left)	3.7	16.9	23.6	3.2	4.9
Hypothyroidism/myxoedema (self-reported)	3.7	7.1	9.5	-3.1	-2.2
Shortness of breath walking on level ground	3.7	4.4	4.9	-2.2	-2.0
Illnesses of siblings: Diabetes	3.7	4.6	6.3	-2.5	-1.7
Forced expiratory volume in 1-second (FEV1), predicted	3.6	7.4	14.8	0.1	-3.8
Breast Cancer	3.5	8.4	15.7	1.0	4.0
Lung FVC	3.5	18.0	25.7	-3.2	5.1
High cholesterol (Self-reported)	3.4	6.0	9.4	1.6	3.1
Hand grip strength (right)	3.1	8.4	16.7	0.2	-4.1
Medication: Ventolin 100micrograms inhaler	3.1	4.0	7.5	-0.7	-2.7
Medication: Levothyroxine sodium	3.0	5.0	7.1	-2.7	-1.7
Waist circumference	3.0	11.1	20.0	-1.5	-4.5
Qualifications: O levels/GCSEs or equivalent	3.0	4.8	6.9	-1.6	-2.6
Asthma	2.9	5.7	8.9	-1.6	-3.0
Asthma (self-reported)	2.9	5.7	8.9	-1.6	-3.0
Ulcerative Colitis	2.8	4.1	7.4	-0.8	-2.7
Hair Pigment	2.8	79.5	80.5	9.0	8.9
HDL Cholesterol	2.7	4.5	8.7	0.5	3.0
Ever unenthusiastic/disinterested for a whole week	2.6	3.1	4.1	-2.0	-1.5
Frequency of tiredness / lethargy in last 2 weeks	2.6	4.3	6.3	-1.5	-2.5
Alcohol intake versus 10 years previously	2.5	3.7	7.3	0.3	-2.7
Type 2 Diabetes (T2D) (2012)	2.4	2.8	3.5	-1.4	-1.9
Frequency of tenseness / restlessness in last 2 weeks	2.4	3.7	4.8	-1.6	-2.2
Illnesses of siblings	2.4	3.3	5.6	2.4	1.0
Intelligence (Savage-Jansen 2018)	2.3	7.1	12.5	1.3	-3.5
Length of working week for main job	2.3	2.5	4.2	0.9	-2.1
Migraine (self-reported)	2.3	2.9	5.3	-0.7	-2.3
Mean time to correctly identify matches	2.3	4.5	8.5	0.7	2.9
Average weekly beer plus cider intake	2.3	3.3	5.6	-2.4	1.0
Basal cell carcinoma (self-reported)	2.3	2.7	2.9	1.7	1.6
LDL Cholesterol	2.2	3.5	6.6	-0.6	2.6
Fluid intelligence score	2.2	4.6	8.7	-0.7	-3.0
Number of self-reported non-cancer illnesses	2.2	3.8	5.5	-2.4	-1.4
Alzheimer’s Disease (in mother)	2.1	2.5	3.8	1.1	2.0
Rheumatoid Arthritis	2.1	2.9	3.8	-1.4	-2.0
Severe depression (siblings)	2.1	2.4	4.4	-2.1	-0.6
Qualifications: CSEs or equivalent	2.1	2.8	5.4	0.3	2.3
Neuroticism score	2.1	4.4	7.7	-1.0	-2.8
Illnesses of mother	2.1	2.6	3.6	-1.3	-1.9
Bipolar Disorder (2018)	2.0	3.2	3.3	-1.8	-1.8
Overall health rating	2.0	4.2	7.1	-2.7	-1.2
Commuting to job workplace: Walk	2.0	2.1	4.0	0.5	-2.0
Guilty feelings	2.0	3.0	4.6	-1.2	-2.1
Verbal and Numeric Reasoning (VNR)	1.9	4.6	8.5	-0.8	-2.9
Neuroticism	1.9	4.6	8.8	-0.7	-3.0
Trunk fat mass	1.9	8.3	16.5	-0.3	-4.1
Financial difficulties in last 2 years	1.9	2.6	3.6	-1.9	-1.2
Peak expiratory flow (PEF)	1.9	4.5	9.0	-0.2	-3.0
Number of children fathered	1.9	2.1	2.2	1.5	1.4
Knee pain experienced in last month	1.9	3.0	3.5	-1.6	1.9
Alzheimer’s Disease (including proxy)	1.8	2.6	5.1	0.3	2.3
Average weekly fortified wine intake	1.8	2.1	3.1	1.8	1.0
Taking other prescription medications	1.8	2.8	3.5	-1.5	-1.9
Number of incorrect matches in round	1.8	3.0	6.1	0.1	2.5
Forced expiratory volume in 1-second (FEV1)	1.8	6.2	11.9	-0.7	-3.5
High blood pressure (siblings)	1.8	2.6	3.2	-1.8	-1.4
Wheeze or whistling in the chest in last year	1.8	3.2	5.3	-1.1	-2.3
Arm fat mass (left)	1.8	7.6	14.1	-1.0	-3.8
Coronary Artery Disease (CAD)	1.7	2.0	3.9	-0.3	-2.0
Number of treatments/medications taken	1.7	3.0	3.3	-1.8	-1.6
Fed-up feelings	1.7	3.2	5.2	-1.0	-2.3
Pulse rate	1.7	2.9	5.7	-2.4	-0.4
Illness, injury, bereavement, stress in last 2 years	1.7	2.1	3.1	1.8	1.0
Long-standing illness, disability or infirmity	1.7	2.7	4.0	-2.0	-1.2
Osteoporosis (self-reported)	1.7	2.1	4.1	-2.0	-0.2
Supplements: Calcium	1.7	1.9	3.3	-1.8	-0.7
Alcohol usually taken with meals	1.6	2.6	3.6	1.9	-1.3
Medication: Lansoprazole	1.6	1.9	2.8	-1.7	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.6	5.1	10.0	-0.5	-3.2
Arm fat mass (right)	1.6	6.5	11.9	-1.0	-3.5
Hair/balding pattern: Pattern 4	1.6	3.8	5.6	1.4	2.4
Whole body fat mass	1.6	6.5	12.9	-0.4	-3.6
Number of operations (self-reported)	1.6	2.4	4.8	-2.2	-0.0
Health satisfaction	1.5	1.9	2.5	-1.1	-1.6
Diabetes diagnosed by doctor	1.5	2.4	4.8	-0.2	-2.2
Heart disease (siblings)	1.5	1.8	3.3	-1.8	-0.6
Major Depression (MDD)	1.4	1.7	2.6	-1.6	-0.9
Eye problems/disorders: Diabetes related eye disease	1.4	1.6	1.9	1.4	-1.1
Medication: Metformin	1.4	2.0	3.8	0.5	-1.9
Number of live births	1.4	2.0	4.0	0.2	2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.1	3.5	-0.9	-1.9
Forced vital capacity (FVC), Best measure	1.4	5.1	9.5	-0.8	-3.1
Medication: Seretide 50 evohaler	1.4	1.6	1.6	-1.3	-1.3
Alzheimer’s Disease (in father)	1.3	1.4	2.2	-0.8	1.5
Ulcerative Colitis (UC)	1.3	2.5	3.6	-1.2	-1.9
Forced vital capacity (FVC)	1.3	5.0	9.5	-0.7	-3.1
Pulse rate, automated reading	1.3	4.3	8.2	-2.9	-0.6
Medication: Lisinopril	1.3	1.7	1.8	-1.3	-1.3
Reaction Time	1.2	2.3	4.7	0.1	2.2
Hand grip strength (left)	1.2	3.1	5.2	1.0	-2.3
Sensitivity / hurt feelings	1.2	2.1	4.1	-2.0	0.0
Diabetes (self-reported)	1.2	1.8	3.7	0.1	-1.9
Medication: Cholesterol lowering	1.2	1.9	2.9	0.9	1.7
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	2.6	-1.6	-0.4
Qualifications: College or University degree	1.2	3.6	3.7	1.9	-1.9
Medication: Ibuprofen	1.2	1.4	2.0	1.4	0.9
Chest pain or discomfort	1.2	1.7	3.2	0.4	-1.8
Financial situation satisfaction	1.2	1.5	2.0	-0.9	-1.4
Myopia	1.2	1.8	3.5	0.4	-1.9
Leg fat mass (left)	1.2	4.9	8.1	-1.3	-2.8
Depression (Nagel 2018)	1.1	1.7	2.9	0.7	-1.7
Neuroticism (2016)	1.1	1.6	1.7	-1.2	-1.3
BMI	1.1	6.2	7.3	-2.3	-2.7
Ever had hysterectomy (womb removed)	1.1	1.2	1.7	0.8	1.3
Townsend deprivation index at recruitment	1.1	1.5	2.5	-1.6	-0.8
Happiness	1.1	1.4	1.5	1.2	-1.1
Exposure to tobacco smoke at home	1.1	1.3	1.6	1.2	-1.0
Supplements: Vitamin C	1.1	1.3	2.5	-1.6	0.0
Back pain experienced in last month	1.1	1.6	3.3	0.1	1.8
Cholesterol lowering medication	1.1	1.6	3.0	0.5	1.7
Bipolar Disorder or Schizophrenia	1.0	2.5	3.2	-1.8	-1.4
Depressed Affect (Nagel 2018)	1.0	2.1	4.1	0.0	-2.0
Crohns Disease (2012)	1.0	1.6	2.9	1.7	-0.6
Triglycerides	1.0	1.6	3.2	0.2	1.8
Blood Red Count	1.0	9.2	12.1	2.5	3.5
Maternal smoking around birth	1.0	1.4	1.9	-1.4	-1.0
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	2.2	-1.5	-0.1
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.1	-1.4	-0.5
Nervous feelings	1.0	1.8	2.4	-1.1	-1.5
Handedness (chirality/laterality): Left-handed	1.0	1.2	1.2	1.1	1.1
Miserableness	1.0	1.8	2.3	-1.1	-1.5
Hearing aid user	1.0	1.2	1.5	0.9	1.2
Eye problems/disorders: Glaucoma	1.0	1.2	1.9	0.7	1.4
Medication: Blood pressure	1.0	2.0	3.7	-0.5	-1.9
Commuting to job workplace: Cycle	1.0	1.2	1.8	1.3	-0.8
Worry (Nagel 2018)	0.9	2.0	3.2	0.8	-1.8
Frequency of depressed mood in last 2 weeks	0.9	1.3	2.5	-0.1	-1.6
Supplements: Zinc	0.9	1.0	1.6	-0.6	-1.3
Relative age voice broke	0.9	1.4	1.5	-1.2	1.2
Serious illness, injury or assault to yourself	0.9	1.1	2.3	-1.5	-0.1
Body mass index (BMI)	0.9	4.0	4.2	-2.0	-2.0
Had menopause	0.9	1.1	1.9	-0.5	-1.4
Tense / ‘highly strung’	0.9	1.5	2.4	-0.8	-1.6
Headache pain in last month	0.9	1.6	2.8	-0.6	-1.7
Exposure to tobacco smoke outside home	0.9	1.2	2.3	0.0	-1.5
Leg fat mass (right)	0.9	3.5	5.9	-1.1	-2.4
Family relationship satisfaction	0.9	1.2	1.7	-0.8	-1.3
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	1.6	1.1	1.2
Wears glasses or contact lenses	0.9	1.0	1.0	1.0	-1.0
Commuting to job workplace: Public transport	0.9	1.0	1.8	0.5	-1.3
Medication: Bendroflumethiazide	0.9	1.3	1.7	-1.0	-1.3
Diastolic blood pressure, automated reading	0.9	2.9	3.5	-1.9	-1.5
Neuroticism (Nagel 2018)	0.8	1.9	3.9	-0.0	-2.0
Lupus	0.8	1.2	2.5	1.6	-0.1
Chronotype (morning person)	0.8	1.9	3.4	-0.6	-1.8
Hair/balding pattern: Pattern 3	0.8	1.1	2.2	1.5	0.2
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	1.6	0.7	1.3
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	1.4	0.8	1.2
Osteoarthritis (self-reported)	0.8	1.0	1.2	-0.9	1.1
Pain type(s) experienced in last month: Hip pain	0.8	1.0	1.7	-1.3	-0.4
Vascular/heart problems diagnosed by doctor	0.8	2.2	2.5	1.6	1.4
Blood Platelet Count	0.7	7.9	15.4	-0.6	-3.9
Lung FEV1/FVC ratio	0.7	3.4	6.7	0.4	-2.6
Medication: Co-codamol	0.7	0.8	1.1	-1.1	-0.7
Diabetes (father)	0.7	0.8	1.3	-0.6	-1.1
Had other major operations	0.7	0.9	1.7	-1.3	-0.1
Qualifications: A levels/AS levels or equivalent	0.7	1.5	2.7	0.6	-1.6
Prospective memory result	0.7	0.8	1.6	-1.3	0.0
Birth weight of first child	0.7	1.2	2.2	-0.5	1.5
Leg fat percentage (right)	0.7	2.4	2.4	-1.6	1.5
Medication: Aspirin	0.7	0.9	1.8	0.3	1.3
Average weekly red wine intake	0.7	1.1	2.1	1.4	0.2
Friendships satisfaction	0.7	0.9	1.5	-1.2	-0.6
Mother’s age at death	0.7	0.9	1.2	0.8	1.1
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.2	0.6	-1.1
Leg fat percentage (left)	0.7	2.5	3.8	-2.0	1.0
Age started oral contraceptive pill	0.7	0.8	1.6	1.3	-0.3
Irritable Bowel Disease (IBD)	0.6	1.5	2.5	-0.7	-1.6
Body Mass Index (BMI) (2010)	0.6	0.8	1.1	1.0	0.7
Blood Eosinophil Count	0.6	4.7	8.2	1.1	-2.9
Average weekly spirits intake	0.6	0.7	0.8	-0.9	0.8
Relative age of first facial hair	0.6	1.3	2.5	-1.6	0.2
Diabetes (mother)	0.6	0.8	1.3	0.4	-1.1
Pack years adult smoking proportion	0.6	1.0	1.3	-0.8	-1.1
Medication: Atenolol	0.6	0.7	1.4	-0.2	-1.2
Past tobacco smoking	0.6	1.1	1.6	1.3	-0.7
Qualifications: None of the above	0.6	1.2	1.6	-0.9	1.3
Medication: Ramipril	0.6	0.7	1.4	1.2	0.1
Worrier / anxious feelings	0.6	1.2	2.4	0.2	-1.5
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.5	-0.1	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	0.9	-1.0	0.7
Smoking status: Previous	0.6	1.0	1.2	-1.1	0.8
Medication: Gliclazide	0.6	0.7	1.0	0.6	-1.0
Risk taking	0.6	0.8	1.0	-0.8	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	1.5	0.2	1.2
Prostate Cancer	0.5	0.7	1.2	-1.1	0.5
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.7	0.5	0.9
High blood pressure	0.5	1.4	2.3	-1.5	-0.7
Multivitamins +/- minerals	0.5	0.6	1.2	0.2	-1.1
Noisy workplace	0.5	0.7	1.3	-1.1	-0.1
Loneliness, isolation	0.5	0.6	0.8	-0.7	-0.9
Schizophrenia vs Biploar Disorder	0.4	0.6	1.1	-1.0	0.2
Bipolar Disorder (2011)	0.4	0.4	0.7	0.8	0.1
Smoking Status	0.4	0.9	1.8	-1.3	-0.1
Supplements: Glucosamine	0.4	0.5	0.7	-0.6	0.8
Chronic bronchitis/emphysema (father)	0.4	0.5	0.9	0.2	1.0
Allergy	0.4	0.9	1.5	0.6	1.2
Father’s age at death	0.4	0.6	0.8	0.9	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.0	-0.0	-1.0
Number of full sisters	0.4	0.4	0.6	-0.8	-0.5
Leg pain on walking	0.4	0.5	0.5	-0.7	-0.7
Commuting to job workplace: Car/motor vehicle	0.4	0.4	0.7	-0.9	0.3
Illnesses of father: Heart disease	0.4	0.6	1.1	-0.2	1.1
Mineral and other dietary supplements	0.4	0.5	0.6	0.7	-0.8
Medication: Aspirin	0.4	0.5	0.9	-0.2	1.0
Supplements: Fish oil (including cod liver oil)	0.4	0.6	1.0	0.3	1.0
Irritability	0.4	0.7	1.3	0.0	-1.1
Pain experienced in last month	0.4	0.6	0.9	1.0	-0.5
Alcohol drinker status: Previous	0.4	0.4	0.8	-0.9	0.1
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.1	-0.1	-1.1
Current tobacco smoking	0.3	0.5	0.5	-0.7	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	0.7	0.1	-0.8
Hayfever, allergic rhinitis or eczema	0.3	0.5	0.9	0.5	0.9
Hair/balding pattern: Pattern 2	0.3	0.4	0.8	-0.9	-0.0
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	0.8	-0.1	-0.9
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.6	0.8	-0.4
Medication: Allopurinol	0.3	0.3	0.4	0.6	0.6
Medication: Omeprazole	0.3	0.3	0.6	-0.3	0.8
Suffer from ‘nerves’	0.3	0.5	0.9	0.4	-1.0
Had major operations	0.3	0.3	0.5	-0.7	0.3
Hypertension (Self-reported)	0.3	0.9	1.6	-1.3	-0.3
Average weekly champagne plus white wine intake	0.3	0.5	0.9	0.0	-0.9
Ever taken oral contraceptive pill	0.3	0.4	0.7	-0.0	0.9
Medication: Paracetamol	0.3	0.5	1.0	1.0	-0.2
Medication: Atorvastatin	0.3	0.3	0.6	-0.8	0.1
Illnesses of father: High blood pressure	0.3	0.4	0.8	0.2	-0.9
Unable to work because of sickness or disability	0.3	0.4	0.8	-0.9	-0.2
Pack years of smoking	0.3	0.4	0.7	-0.4	-0.8
Age at First Birth	0.2	0.3	0.6	0.1	0.8
Fasting Glucose	0.2	0.2	0.3	0.4	0.5
Vitamin and mineral supplements	0.2	0.2	0.4	0.3	0.6
Age when periods started (menarche)	0.2	0.5	1.1	1.0	-0.0
Stomach or abdominal pain in last month	0.2	0.2	0.5	-0.7	-0.2
High blood pressure (mother)	0.2	0.2	0.3	-0.6	-0.4
Mouth/teeth dental problems	0.2	0.3	0.7	0.0	-0.8
Pain all over the body in last month	0.2	0.2	0.5	-0.0	-0.7
Arm fat percentage (right)	0.2	0.6	1.2	-1.1	-0.1
Falls in the last year	0.2	0.2	0.4	-0.2	-0.6
Lung cancer (father)	0.2	0.2	0.3	-0.4	-0.5
Pulse wave Arterial Stiffness index	0.2	0.2	0.4	-0.2	-0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.6	-0.3	-0.8
Gout (self-reported)	0.2	0.3	0.4	0.6	0.5
Medication: Amlodipine	0.2	0.3	0.5	-0.7	0.4
Age at first live birth	0.2	0.3	0.5	-0.7	0.1
Emphysema/chronic bronchitis	0.2	0.3	0.4	0.4	0.6
Angina (self-reported)	0.2	0.2	0.4	-0.3	-0.6
Heart disease (mother)	0.2	0.3	0.5	0.7	0.2
Arm fat percentage (left)	0.2	0.6	1.1	-1.1	-0.3
Medication for cholesterol	0.2	0.4	0.6	0.3	0.8
Illnesses of father: None of the above (group 1)	0.2	0.2	0.3	0.4	0.6
Smoking status: Current	0.2	0.4	0.6	-0.5	-0.8
Ever smoked	0.2	0.4	0.7	-0.9	-0.3
Fractured/broken bones in last 5 years	0.2	0.2	0.3	0.4	0.5
Ever depressed for a whole week	0.2	0.3	0.6	-0.7	0.1
Schizophrenia (2018)	0.1	0.2	0.2	-0.5	-0.3
Crohns Disease (2017)	0.1	0.1	0.2	0.5	-0.0
Mean Putamen Volume	0.1	0.1	0.1	-0.3	0.2
HbA1C	0.1	0.1	0.2	0.1	-0.4
Primary Biliary Cirrhosis	0.1	0.2	0.3	0.6	-0.2
Schizophrenia (2014)	0.1	0.2	0.4	-0.2	-0.6
Blood White Count	0.1	0.5	0.6	-0.7	0.7
Heel T-Score	0.1	0.8	1.2	1.1	0.7
Waist Hip Ratio (WHR)	0.1	0.5	0.5	-0.7	0.7
Systolic Blood Pressure	0.1	0.6	0.9	0.5	-0.9
Cardiovascular Disease	0.1	0.3	0.3	-0.6	0.5
Hearing difficulty/problems: Yes	0.1	0.2	0.3	0.1	0.6
Angina	0.1	0.1	0.2	-0.2	-0.4
Trunk fat percentage	0.1	0.3	0.5	-0.3	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.6	0.8	-0.0
Hearing difficulty/problems with background noise	0.1	0.1	0.2	-0.4	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.1	0.2	0.4	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.1	-0.1	0.4
Pulse wave reflection index	0.1	0.1	0.2	0.1	-0.5
Medication: Paracetamol	0.1	0.2	0.3	0.4	-0.6
Glaucoma (self-reported)	0.1	0.1	0.2	0.1	0.4
Birth weight	0.1	0.2	0.3	-0.3	-0.6
Body fat percentage	0.1	0.3	0.6	-0.8	0.1
Comparative body size at age 10	0.1	0.3	0.6	-0.8	-0.2
Number of full brothers	0.1	0.2	0.3	-0.2	-0.5
Worry too long after embarrassment	0.1	0.1	0.2	0.2	-0.4
Pulse wave peak to peak time	0.1	0.2	0.3	0.6	-0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.1	-0.4	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.3	-0.3	0.5
Age at last live birth	0.1	0.1	0.2	-0.3	-0.4
Ever had bowel cancer screening	0.1	0.1	0.2	-0.3	-0.4
Eye problems/disorders: Cataract	0.1	0.1	0.2	-0.1	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.4	-0.4	0.6
Alcohol drinker status: Never	0.1	0.1	0.2	0.4	0.1
Ever had prostate specific antigen (PSA) test	0.1	0.2	0.2	0.5	-0.3
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.1	-0.4	-0.2
Allergy or Eczema	0.0	0.1	0.2	0.4	0.0
Ever used hormone-replacement therapy (HRT)	0.0	0.0	0.1	-0.2	0.2
Systolic blood pressure, automated reading	0.0	0.1	0.1	0.3	0.1
Medication for hormone replacement therapy	0.0	0.0	0.0	-0.0	0.2
Heart attack	0.0	0.1	0.1	-0.3	-0.2
Mouth/teeth dental problems: Dentures	0.0	0.0	0.1	0.3	0.1
Depression (self-reported)	0.0	0.0	0.1	-0.2	-0.3
Breastfed as a baby	0.0	0.0	0.1	0.0	-0.3
Loud music exposure frequency	0.0	0.0	0.0	-0.1	0.1
Mouth/teeth dental problems: Bleeding gums	0.0	0.0	0.0	-0.1	0.1
Eye problems/disorders: None of the above	0.0	0.0	0.1	-0.1	-0.2
Medication for pain relief, constipation, heartburn	0.0	0.0	0.0	0.2	-0.2
Neck or shoulder pain in last month	0.0	0.0	0.0	-0.0	-0.1
Medication: Blood pressure	0.0	0.0	0.0	-0.2	0.1
Alcohol intake frequency.	0.0	0.1	0.2	0.0	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.1	0.2	0.0
Qualifications: nursing, teaching	0.0	0.1	0.1	0.4	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.0	0.0	-0.1

Hub : Genes

SCAND1

Models

Trait associations