Hub : Genes

SCAP

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1860 0.0630 0.0e+00 0.167 0.170 0.165 0.167 0.164 8.3e-20 3.4e-20 1.5e-19 7.7e-20 1.6e-19
2 GTEx Adipose Subcutaneous 0.2160 0.0730 1.0e-03 0.014 NA 0.057 NA 0.027 2.2e-02 NA 2.0e-05 NA 2.7e-03
3 GTEx Brain Frontal Cortex BA9 0.1395 0.0801 4.2e-04 0.188 NA 0.123 NA 0.151 1.1e-05 NA 3.9e-04 NA 8.1e-05
4 GTEx Cells Transformed fibroblasts 0.0880 0.0400 6.7e-08 0.082 NA 0.077 NA 0.084 1.0e-06 NA 2.2e-06 NA 7.3e-07
5 GTEx Esophagus Mucosa 0.0350 0.0190 1.2e-03 0.036 NA 0.023 NA 0.021 1.9e-03 NA 1.1e-02 NA 1.3e-02
6 GTEx Esophagus Muscularis 0.1780 0.0730 2.8e-04 0.016 NA 0.008 NA 0.029 3.5e-02 NA 9.5e-02 NA 6.5e-03
7 GTEx Skin Not Sun Exposed Suprapubic 0.0970 0.0720 3.7e-03 -0.002 NA 0.024 NA 0.012 4.3e-01 NA 1.8e-02 NA 7.0e-02
8 GTEx Skin Sun Exposed Lower leg 0.2930 0.0780 2.1e-08 0.033 NA 0.121 NA 0.135 8.4e-04 NA 3.2e-10 NA 2.8e-11
9 GTEx Spleen 0.1350 0.0820 2.8e-03 0.093 NA 0.044 NA 0.075 2.3e-03 NA 2.9e-02 NA 5.6e-03
10 GTEx Whole Blood 0.0680 0.0420 3.5e-05 0.023 NA 0.012 NA 0.020 3.2e-03 NA 2.3e-02 NA 5.1e-03
11 NTR Blood 0.0167 0.0078 4.4e-08 0.015 0.022 0.017 0.020 0.016 1.2e-05 9.3e-08 2.4e-06 4.1e-07 6.0e-06
12 ROSMAP Brain Pre-frontal Cortex 0.1536 0.0505 0.0e+00 0.156 0.203 0.198 0.196 0.192 1.4e-19 1.5e-25 7.6e-25 1.2e-24 4.0e-24
13 TCGA Bladder Urothelial Carcinoma 0.0520 0.0380 1.1e-03 0.014 0.020 0.016 NA 0.018 2.3e-02 7.1e-03 1.6e-02 NA 1.1e-02
14 TCGA Breast Invasive Carcinoma 0.0340 0.0249 6.9e-05 0.020 0.016 0.011 NA 0.014 4.0e-05 2.0e-04 1.9e-03 NA 4.5e-04
15 TCGA Head and Neck Squamous Cell Carcinoma 0.0376 0.0315 8.1e-04 0.033 0.024 0.032 NA 0.029 1.3e-04 9.3e-04 1.6e-04 NA 3.1e-04
16 TCGA Brain Lower Grade Glioma 0.0277 0.0171 1.5e-04 0.028 0.029 0.023 NA 0.028 3.1e-04 2.8e-04 1.2e-03 NA 3.1e-04
17 TCGA Lung Adenocarcinoma 0.0291 0.0210 1.1e-03 0.022 0.024 0.026 NA 0.022 1.2e-03 6.7e-04 4.6e-04 NA 1.1e-03
18 TCGA Ovarian Serous Cystadenocarcinoma 0.0330 0.0230 3.5e-03 0.023 0.026 0.020 NA 0.022 1.0e-02 6.5e-03 1.5e-02 NA 1.1e-02
19 TCGA Pancreatic Adenocarcinoma 0.0830 0.0600 4.6e-04 0.076 0.057 0.020 NA 0.054 4.3e-04 2.2e-03 4.8e-02 NA 2.8e-03
20 TCGA Prostate Adenocarcinoma 0.0253 0.0162 5.2e-04 0.018 0.014 0.010 NA 0.009 4.6e-03 1.3e-02 2.9e-02 NA 3.6e-02
21 TCGA Rectum Adenocarcinoma 0.2170 0.1530 7.8e-03 -0.012 0.025 -0.005 NA -0.004 7.8e-01 8.6e-02 4.4e-01 NA 4.2e-01
22 TCGA Soft Tissue Sarcoma 0.0720 0.0500 2.0e-04 0.033 0.038 0.040 NA 0.047 4.4e-03 2.7e-03 2.1e-03 NA 8.7e-04
23 TCGA Uterine Corpus Endometrial Carcinoma 0.2410 0.1270 2.8e-04 0.054 0.100 0.066 NA 0.058 1.3e-02 1.0e-03 6.7e-03 NA 1.0e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Bipolar Disorder (2018) 3.1 5.0 14.1 1.4 3.4 1.9 2.0 2.0 3.8 2.9 3.5 1.4 -2.3 -2.1 1.9 1.8 2.0 1.9 2.1 1.4 2.0 1.9 2.1 1.9 1.9 1.8
Bipolar Disorder or Schizophrenia 1.4 3.4 9.1 1.5 2.9 1.7 1.8 1.6 2.3 2.7 3.0 1.4 -1.9 -1.0 1.4 2.1 1.9 1.6 1.8 0.6 1.6 1.5 1.9 1.5 1.5 1.1
Depressed Affect (Nagel 2018) 0.6 1.3 3.4 0.0 0.9 1.2 1.7 1.0 1.8 0.9 1.3 1.9 -1.2 -1.5 1.0 1.4 1.1 0.2 1.1 0.4 0.9 0.8 1.2 0.9 1.0 0.8
Depression (Nagel 2018) 0.8 1.3 6.4 0.3 1.7 1.1 0.9 0.5 2.5 0.8 1.0 1.0 -1.1 -1.1 1.1 1.1 1.1 0.6 1.0 0.8 1.0 1.1 1.1 1.1 1.1 1.2
Intelligence (Savage-Jansen 2018) 0.2 0.8 2.1 1.4 0.8 1.0 0.2 0.8 0.9 0.9 0.1 0.5 -0.8 -0.1 1.2 1.4 1.1 0.7 0.9 0.4 0.9 1.1 0.9 0.8 0.8 1.0
Neuroticism (Nagel 2018) 0.2 0.4 2.7 -0.2 1.3 0.4 0.7 -0.0 -0.1 0.9 1.6 0.7 -0.4 -0.3 0.6 1.2 0.6 0.2 0.4 -0.8 0.1 0.1 0.5 0.1 0.1 -0.3
Schizophrenia (2018) 0.2 0.4 1.4 0.8 1.0 0.6 0.6 0.4 -0.0 1.1 1.1 0.7 -0.6 0.4 0.3 1.2 0.9 0.5 0.7 -0.4 0.4 0.4 0.7 0.3 0.4 0.0
Schizophrenia vs Biploar Disorder 2.6 3.5 5.4 -1.4 -1.6 -2.0 -1.8 -1.8 -2.3 -2.0 -1.9 -1.5 1.9 2.3 -1.6 -1.2 -1.8 -1.6 -2.0 -1.9 -2.0 -1.8 -1.9 -2.0 -2.0 -2.0
Worry (Nagel 2018) 0.4 0.8 5.0 0.6 1.2 0.6 0.7 0.5 -0.4 1.5 2.2 0.5 -0.5 0.2 0.6 1.3 0.8 1.1 0.8 -0.0 0.5 0.6 0.8 0.6 0.4 -0.0
Alzheimer’s Disease (in mother) 1.0 1.2 3.1 1.3 1.3 1.2 0.3 0.2 1.0 0.8 0.3 1.7 -0.8 -0.4 0.6 0.9 1.1 -0.2 1.0 1.4 1.2 1.2 1.1 1.3 1.4 1.8
Alzheimer’s Disease (in father) 0.1 0.1 0.7 -0.2 0.1 -0.1 -0.1 -0.0 0.5 0.2 0.3 -0.4 0.4 0.4 -0.9 -0.5 -0.3 0.5 -0.0 0.6 0.0 0.0 -0.1 0.1 0.0 0.0
Alzheimer’s Disease (including proxy) 0.7 1.0 2.8 1.2 1.1 1.3 0.3 0.4 1.2 1.1 0.5 1.4 -0.3 -0.0 -0.0 0.7 0.9 0.1 1.0 1.6 1.2 1.2 1.1 1.3 1.2 1.7
Crohns Disease (2017) 1.8 3.9 13.2 1.1 1.8 2.0 1.6 1.4 1.6 2.5 3.6 1.3 -2.1 -1.5 1.6 2.3 2.2 2.2 1.9 1.4 1.9 2.1 1.8 1.9 1.9 1.8
Irritable Bowel Disease (IBD) 0.9 2.2 10.7 0.2 2.0 1.3 0.9 0.7 2.0 1.7 3.3 0.0 -1.4 -0.7 1.2 1.7 1.7 2.4 1.2 0.8 1.2 1.5 1.1 1.2 1.1 0.9
Ulcerative Colitis (UC) 0.4 0.8 3.9 -0.2 1.5 0.6 0.2 0.1 1.6 0.7 1.8 -0.8 -0.6 -0.0 0.7 1.0 0.9 2.0 0.6 0.1 0.6 0.8 0.5 0.5 0.4 0.2
Major Depression (MDD) 0.2 0.2 1.2 -1.1 -0.3 -0.4 -0.0 -0.3 0.5 -0.9 -0.1 -0.2 0.0 0.5 -0.5 -0.7 -0.5 -0.4 -0.4 0.3 -0.3 -0.3 -0.4 -0.3 -0.3 -0.1
Reaction Time 9.5 18.0 25.2 -4.5 -1.3 -4.6 -4.4 -4.7 -3.3 -3.5 -2.3 -4.0 4.2 4.5 -4.1 -3.6 -4.5 -4.0 -4.5 -4.9 -4.8 -4.7 -4.5 -4.9 -4.9 -5.0
Verbal and Numeric Reasoning (VNR) 1.3 3.2 8.1 2.8 0.6 2.2 1.0 1.5 0.2 1.4 0.1 1.5 -1.6 -0.9 2.2 2.4 2.1 1.4 2.1 1.5 2.0 2.1 2.1 2.0 2.0 2.1
Breast Cancer 0.8 1.8 5.2 1.1 -0.5 1.6 0.7 0.3 1.7 -1.7 -1.9 2.3 -0.6 -0.4 0.3 0.6 0.8 -0.8 1.4 1.8 1.5 1.3 1.5 1.5 1.4 2.2
Ovarian Cancer 2.9 3.8 6.2 -1.5 -2.0 -1.9 -2.2 -2.1 -2.5 -1.9 -1.9 -1.9 2.0 2.0 -1.6 -1.5 -1.8 -1.5 -2.0 -2.1 -2.0 -2.0 -1.9 -2.1 -2.0 -2.1
Prostate Cancer 0.4 0.5 1.9 1.3 0.8 0.9 0.6 0.5 -1.1 0.4 0.1 1.1 -0.5 -0.1 0.9 1.4 0.7 -0.1 0.9 -0.2 0.5 0.4 0.9 0.5 0.4 0.3
Age at First Birth 1.8 2.7 7.4 -1.4 -0.4 -1.7 -2.1 -1.8 -0.5 -0.2 -0.0 -0.6 1.8 2.7 -2.4 -1.4 -1.8 -2.2 -1.8 -1.7 -1.8 -1.6 -1.7 -1.6 -1.7 -1.3
Bipolar Disorder (2011) 5.3 5.1 10.2 2.3 0.0 2.2 2.8 2.8 2.9 3.2 0.0 1.9 -2.9 -2.1 2.1 1.9 2.3 2.4 2.4 1.7 2.3 2.2 2.3 2.2 2.2 1.9
Body Mass Index (BMI) (2010) 0.7 0.9 3.1 -0.1 1.2 0.9 1.0 0.8 1.4 1.8 1.6 1.5 -0.8 -1.3 0.5 0.4 0.6 0.0 0.7 0.6 0.8 0.7 0.8 0.9 0.9 1.0
Coronary Artery Disease (CAD) 1.3 1.5 6.6 -0.3 -2.6 -0.8 -1.0 -0.5 -1.0 -1.7 -2.3 -1.2 0.9 1.6 -1.6 -1.8 -1.1 -0.0 -1.1 0.5 -0.8 -0.8 -1.2 -0.6 -0.7 -0.5
Crohns Disease (2012) 2.5 4.1 12.8 1.3 2.0 2.0 1.9 1.7 2.4 3.2 3.6 1.7 -2.2 -1.7 1.6 1.9 1.9 1.6 2.1 1.0 1.9 1.8 2.0 1.9 1.8 1.6
Mean Putamen Volume 0.3 0.4 1.8 -0.6 -0.0 -0.6 -0.6 -0.5 1.0 -0.2 -0.0 -0.4 0.4 -0.0 -0.9 -1.4 -1.0 -0.9 -0.7 0.3 -0.5 -0.4 -0.7 -0.3 -0.3 0.1
Fasting Glucose 0.7 0.8 2.1 1.2 -1.4 0.9 0.7 1.0 -1.4 0.0 -0.4 1.2 -0.8 0.2 0.6 0.9 0.9 1.1 0.9 0.5 0.9 1.0 0.9 0.8 0.8 0.8
HbA1C 1.0 1.1 2.9 -1.2 -0.2 -1.0 -1.4 -1.4 -0.7 -1.0 -0.1 -1.0 1.3 1.7 -1.6 -0.5 -0.9 -1.0 -1.0 -0.9 -1.0 -1.0 -0.9 -1.1 -1.3 -1.0
HDL Cholesterol 2.7 4.5 6.7 2.5 -0.2 2.5 2.3 2.5 1.2 1.6 1.1 2.4 -2.6 -2.1 2.1 1.9 2.3 1.9 2.4 2.0 2.4 2.2 2.4 2.3 2.2 2.2
LDL Cholesterol 0.1 0.1 1.1 0.5 -0.9 0.3 -0.1 0.0 0.1 -0.6 -1.1 0.3 0.1 0.1 0.0 -0.2 -0.0 -0.3 0.1 0.4 0.2 0.1 0.1 0.2 0.2 0.4
Lupus 1.2 1.8 6.6 -0.5 -2.1 -0.8 -1.3 -1.4 0.2 -2.3 -2.6 -0.6 1.6 0.8 -2.2 -2.3 -1.3 -1.4 -0.9 0.7 -0.5 -0.7 -0.9 -0.3 -0.1 0.4
Neuroticism (2016) 1.6 2.3 5.4 1.2 1.1 1.5 1.9 1.9 0.4 2.2 2.3 1.9 -1.6 -1.3 1.6 2.0 1.7 0.9 1.5 0.1 1.3 1.2 1.6 1.2 1.1 1.0
Primary Biliary Cirrhosis 0.2 0.3 2.0 -0.1 -1.1 -0.4 -0.6 -0.3 0.3 -0.9 -1.4 -0.6 0.6 -0.5 -0.4 -0.9 -0.5 0.1 -0.4 0.7 -0.2 -0.1 -0.4 -0.1 -0.1 0.0
Rheumatoid Arthritis 0.4 0.6 1.2 -0.7 -0.2 -0.9 -0.9 -0.8 -0.4 -0.1 -0.3 -0.8 0.7 0.7 -0.8 -1.0 -1.1 -0.9 -1.0 -0.8 -0.9 -0.9 -1.0 -0.8 -0.8 -0.7
Schizophrenia (2014) 0.0 0.1 0.3 0.4 0.6 0.1 0.2 0.2 0.1 0.6 0.6 0.2 -0.4 0.6 -0.0 0.4 0.2 -0.1 0.2 -0.4 0.1 0.1 0.2 0.1 0.1 -0.0
Triglycerides 2.0 3.3 4.8 -1.8 -0.8 -1.9 -1.9 -1.8 -1.4 -1.7 -1.4 -2.1 2.0 2.1 -2.2 -1.9 -2.1 -1.5 -2.1 -1.3 -1.9 -1.8 -2.1 -1.9 -1.9 -1.6
Type 2 Diabetes (T2D) (2012) 7.1 8.1 11.7 -2.9 -0.9 -2.9 -3.0 -3.1 -2.4 -2.3 -1.2 -3.4 3.0 3.4 -3.0 -2.4 -2.9 -1.8 -3.2 -2.8 -3.2 -2.9 -3.3 -3.1 -3.2 -3.2
Ulcerative Colitis 0.2 0.3 1.9 -0.8 1.4 -0.1 -0.5 -0.5 1.2 0.3 1.1 -0.9 0.1 0.3 0.1 -0.2 -0.0 1.0 -0.1 0.1 -0.1 0.0 -0.2 -0.1 -0.2 -0.3
Blood Eosinophil Count 0.8 6.3 12.1 -2.8 1.4 -2.9 -2.9 -2.9 0.8 -1.2 -0.8 -3.2 3.0 2.0 -2.8 -3.5 -3.2 -1.9 -2.9 -1.2 -2.7 -2.5 -3.0 -2.4 -2.5 -2.3
Blood Platelet Count 0.7 7.7 22.0 1.7 1.9 2.8 3.0 2.7 2.0 3.4 4.7 2.2 -3.1 -2.2 2.2 2.8 2.7 3.1 2.8 2.2 2.8 3.1 2.7 2.8 2.7 2.7
Blood Red Count 0.2 2.1 7.3 -0.4 -2.4 -1.0 -1.2 -0.7 -1.4 -1.7 -1.8 0.4 1.3 2.7 -2.5 -1.9 -1.4 -2.1 -1.0 0.4 -0.8 -1.1 -0.9 -0.7 -0.8 -0.3
Blood White Count 16.2 119.9 163.8 -12.5 -3.0 -11.7 -11.9 -12.8 -7.6 -8.3 -4.2 -10.6 12.1 11.7 -12.2 -10.0 -11.7 -10.8 -11.6 -11.4 -12.0 -11.9 -11.6 -11.9 -12.0 -11.7
Heel T-Score 4.2 33.3 51.4 -6.3 -2.8 -6.0 -6.9 -6.4 -2.5 -4.5 -3.6 -6.7 7.0 6.8 -7.2 -6.6 -6.3 -5.0 -6.2 -4.1 -5.8 -5.9 -6.2 -5.7 -5.6 -5.2
BMI 0.9 5.3 15.5 0.1 2.0 2.4 3.0 2.1 2.9 1.0 1.3 2.7 -2.1 -3.9 2.8 2.1 2.4 1.4 2.5 1.7 2.3 2.0 2.6 2.2 2.3 2.0
Height 1.2 22.8 69.2 -4.0 -5.7 -4.6 -4.5 -3.6 0.1 -4.2 -3.8 -0.5 4.8 4.8 -8.3 -8.3 -6.1 -7.5 -5.3 1.6 -4.0 -4.2 -5.1 -3.2 -3.1 -0.9
Waist Hip Ratio (WHR) 8.7 39.2 53.1 -7.1 -1.1 -6.9 -7.0 -7.3 -4.5 -4.1 -2.6 -5.6 7.0 6.1 -6.3 -6.1 -7.1 -6.8 -6.8 -6.5 -7.0 -6.9 -6.8 -6.8 -6.8 -6.5
Systolic Blood Pressure 1.3 6.7 27.6 -0.7 -1.2 -1.9 -3.5 -3.6 -3.6 -4.1 -2.6 -2.6 2.5 5.2 -3.0 -1.7 -1.7 -1.4 -1.8 -1.7 -1.9 -1.9 -1.8 -2.0 -2.0 -2.0
Smoking Status 2.5 6.0 15.4 1.8 0.7 2.5 3.3 2.7 2.2 0.8 0.6 2.0 -2.9 -3.9 3.2 2.8 3.0 2.8 2.8 1.6 2.5 2.3 2.7 2.3 2.2 1.7
Allergy or Eczema 5.2 13.8 17.0 4.0 3.1 4.0 3.7 3.6 3.1 3.4 2.6 3.8 -3.8 -3.4 4.0 3.6 3.6 3.0 4.0 3.8 4.0 4.1 4.0 4.1 4.0 4.1
Cardiovascular Disease 0.5 1.7 9.3 -0.5 -1.2 -0.8 -1.5 -1.5 -2.5 -2.4 -1.3 -0.9 0.9 3.0 -1.5 -0.5 -0.4 -0.6 -0.8 -1.0 -0.8 -0.8 -0.7 -1.0 -0.8 -0.9
Hypothyroidism (self reported) 1.2 2.7 7.3 1.5 1.4 1.8 1.9 1.3 0.1 1.5 1.7 2.6 -1.7 -0.8 2.0 2.7 1.9 0.5 1.8 0.6 1.6 1.6 1.9 1.6 1.5 1.5
Respiratory disease 0.6 1.4 4.5 0.6 0.9 1.4 1.1 0.5 0.8 0.5 0.4 1.2 -1.0 -2.1 1.6 1.2 1.4 0.5 1.2 0.8 1.3 1.2 1.3 1.3 1.3 1.5
Type 2 Diabetes (T2D) (2018) 4.1 7.7 11.8 -3.0 -1.0 -2.9 -3.3 -3.4 -2.4 -3.3 -2.2 -3.3 3.2 2.9 -2.8 -2.5 -2.5 -2.2 -2.8 -2.4 -2.8 -2.8 -2.8 -2.9 -2.8 -2.8
Lung FEV1/FVC ratio 2.4 12.2 16.1 -3.7 -2.6 -4.0 -4.0 -3.3 -0.0 -3.1 -3.4 -3.9 3.8 2.8 -3.7 -4.0 -3.7 -2.8 -4.0 -2.8 -3.8 -3.8 -4.0 -3.8 -3.8 -3.6
Lung FVC 0.2 0.9 4.2 -0.2 -0.6 -0.9 -1.4 -0.7 0.0 -0.2 -0.6 -2.0 0.9 1.5 -0.5 -0.8 -0.7 0.5 -0.9 -0.8 -0.9 -0.7 -1.1 -1.0 -0.9 -1.1
Neuroticism 0.7 1.7 4.9 1.3 -0.2 1.3 1.7 1.2 -1.5 1.1 1.3 1.3 -1.7 -0.8 1.7 2.2 1.8 1.6 1.3 -0.2 1.1 1.0 1.4 0.9 1.0 0.3
Chronotype (morning person) 2.7 6.2 10.8 -2.5 -2.9 -2.5 -2.0 -2.2 -1.9 -3.1 -2.2 -2.5 2.4 3.3 -3.0 -2.5 -2.3 -1.3 -2.5 -2.1 -2.4 -2.5 -2.5 -2.7 -2.5 -2.7
Hair Pigment 0.1 2.1 6.2 1.5 -1.8 1.4 1.2 1.4 0.2 -0.2 -1.3 1.5 -0.9 -2.5 0.9 0.3 1.2 1.0 1.3 2.4 1.7 1.5 1.3 1.6 1.7 2.1
Tanning 0.1 0.8 2.8 -0.7 -0.4 -0.9 -0.9 -0.7 -1.2 -0.5 -0.5 -1.3 1.0 0.6 -0.3 -0.0 -0.6 -0.2 -0.7 -1.7 -1.0 -0.9 -0.8 -1.1 -1.1 -1.4
Hand grip strength (left) 0.8 2.1 10.4 1.1 -1.2 1.0 1.6 1.9 3.2 -0.2 -0.4 1.2 -1.2 -1.1 -0.3 -1.0 0.6 0.9 0.9 3.1 1.4 1.1 0.8 1.5 1.6 1.9
Number of treatments/medications taken 0.6 1.1 3.1 1.2 -0.9 1.0 1.1 0.8 -1.2 -0.3 -0.7 1.8 -1.0 -0.2 1.4 1.6 1.4 0.5 1.2 0.1 1.0 1.0 1.3 0.8 1.0 0.9
Average weekly spirits intake 1.6 2.0 4.8 1.3 -1.4 1.3 2.1 2.0 -0.2 0.9 -0.1 2.0 -1.3 -2.2 1.2 0.6 0.9 0.8 1.4 1.7 1.4 1.3 1.4 1.4 1.5 1.5
Sensitivity / hurt feelings 0.3 0.5 1.6 0.2 0.7 0.7 0.8 0.4 -0.7 0.4 1.2 0.3 -0.6 -0.5 0.9 1.2 0.9 0.9 0.6 -0.1 0.6 0.6 0.7 0.4 0.4 0.3
Frequency of depressed mood in last 2 weeks 0.1 0.2 1.6 -0.3 1.3 0.0 -0.1 -0.4 0.8 0.0 0.7 -0.5 0.1 0.1 -0.0 0.3 0.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 -0.0 -0.2
Hearing difficulty/problems: Yes 2.1 3.1 9.4 -3.1 0.5 -2.0 -1.6 -1.9 -0.3 -1.0 -0.3 -1.5 1.7 0.8 -0.9 -1.5 -2.0 -2.0 -2.1 -2.2 -2.1 -2.0 -2.0 -2.1 -2.1 -1.9
Relative age of first facial hair 0.4 0.9 2.2 1.3 1.5 1.0 0.5 0.6 0.3 0.8 1.2 0.0 -1.2 -0.4 1.3 1.4 1.1 1.3 0.9 0.5 0.9 1.0 0.9 0.9 0.7 0.7
Other serious medical condition/disability diagnosed by doctor 1.0 1.4 4.4 1.7 1.0 1.3 0.6 0.7 0.1 1.3 1.0 1.7 -1.0 -0.1 1.2 2.1 1.5 0.5 1.3 0.2 1.1 1.3 1.3 1.1 1.0 1.2
Ever used hormone-replacement therapy (HRT) 0.2 0.3 1.7 -0.6 0.8 -0.5 -0.3 -0.6 -0.5 -0.0 0.3 0.2 0.1 0.1 -0.1 0.1 -0.4 -1.3 -0.5 -0.9 -0.6 -0.5 -0.4 -0.5 -0.6 -0.4
Ever had hysterectomy (womb removed) 1.8 2.0 4.2 1.8 1.4 1.2 1.4 1.3 -0.7 1.5 1.0 1.5 -1.5 -1.7 2.0 1.8 1.6 1.0 1.5 0.9 1.3 1.4 1.5 1.3 1.3 1.2
Systolic blood pressure, automated reading 0.2 0.6 3.6 0.3 0.0 0.2 -0.8 -1.1 -1.4 -1.7 -1.1 0.3 0.6 1.9 -0.8 0.1 0.1 -0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.1 0.3
Eye problems/disorders: Diabetes related eye disease 1.5 1.7 4.0 -1.5 -0.2 -1.3 -1.6 -2.0 -1.2 -1.3 -0.4 -1.9 1.5 1.6 -1.5 -0.8 -1.0 -0.8 -1.2 -1.3 -1.2 -1.1 -1.2 -1.3 -1.1 -1.1
Angina 1.0 1.3 3.3 -1.5 -1.3 -0.9 -1.3 -1.5 -1.1 -1.0 -1.1 -0.4 1.6 0.9 -1.0 -0.7 -0.9 -1.8 -0.9 -1.6 -1.0 -1.0 -0.8 -1.0 -0.9 -0.7
Medication for hormone replacement therapy 0.2 0.2 1.3 -0.3 1.1 -0.2 -0.4 -0.5 0.1 0.6 0.9 0.2 0.3 0.4 -0.4 0.1 -0.4 -0.8 -0.2 -0.4 -0.3 -0.2 -0.2 -0.2 -0.3 -0.1
Vitamin and mineral supplements 10.3 14.0 18.0 -3.9 -1.6 -3.9 -4.1 -4.1 -2.9 -2.6 -2.1 -3.4 4.0 4.1 -3.9 -3.3 -4.1 -4.2 -3.8 -4.1 -4.1 -4.2 -3.8 -4.1 -4.1 -4.1
Supplements: Zinc 0.9 0.9 1.8 1.3 -0.7 0.9 1.2 1.2 -0.4 0.5 -0.0 1.0 -1.2 -0.8 1.0 0.7 1.0 1.1 0.9 0.9 1.0 1.0 0.9 1.0 1.1 1.1
Medication: Co-codamol 0.6 0.7 3.5 -1.0 -0.2 -0.9 -0.3 -0.4 -0.8 -0.7 -1.1 0.2 0.5 -0.3 0.5 0.0 -0.4 -1.0 -0.7 -1.9 -0.9 -0.9 -0.7 -1.1 -1.0 -1.2
Medication: Metformin 3.5 5.0 9.1 -2.1 -2.6 -2.1 -2.1 -2.4 -2.9 -2.9 -2.1 -2.1 2.2 3.0 -2.5 -2.0 -1.9 -1.7 -2.1 -1.8 -2.0 -2.0 -2.1 -2.2 -2.0 -1.9
Diabetes (father) 1.5 1.9 3.5 -1.5 -0.8 -1.2 -1.6 -1.9 -1.5 -1.9 -1.1 -1.5 1.3 1.5 -1.0 -0.8 -1.1 -1.5 -1.3 -1.8 -1.3 -1.4 -1.2 -1.4 -1.3 -1.4
Diabetes (mother) 5.1 6.4 10.0 -2.4 -1.3 -2.4 -3.0 -3.0 -3.2 -2.7 -1.7 -2.8 2.5 3.0 -2.5 -2.1 -2.3 -2.1 -2.5 -2.7 -2.5 -2.5 -2.6 -2.6 -2.7 -2.5
Severe depression (siblings) 0.9 1.1 2.2 1.3 0.6 1.0 0.8 0.8 0.5 0.3 0.5 0.6 -1.1 -0.5 0.9 1.2 1.3 1.5 1.2 1.3 1.2 1.3 1.2 1.2 1.1 1.2
Pack years adult smoking proportion 1.4 2.2 4.0 -1.2 -2.0 -1.6 -1.2 -1.5 -1.5 -1.5 -1.4 -0.8 1.4 1.8 -2.0 -1.4 -1.3 -1.6 -1.4 -1.2 -1.4 -1.6 -1.3 -1.5 -1.4 -1.4
Impedance of leg (right) 1.8 8.5 16.2 -1.8 -1.3 -3.1 -3.4 -3.0 -2.8 -2.3 -2.0 -2.1 2.6 3.7 -4.0 -3.6 -3.7 -3.6 -3.0 -1.7 -3.0 -3.0 -3.1 -2.8 -2.9 -2.4
Leg fat-free mass (left) 0.2 0.8 3.8 -0.6 -0.7 0.6 0.9 0.6 1.9 -0.2 -0.1 1.6 0.1 -1.0 -0.5 -0.7 0.2 -0.8 0.2 1.9 0.6 0.3 0.4 0.8 0.9 1.3
Trunk fat percentage 0.1 0.6 3.2 -0.7 -0.1 0.6 1.1 0.6 0.8 0.3 0.3 1.8 -0.4 -1.4 -0.3 -0.3 0.1 -1.0 0.5 1.0 0.5 0.3 0.6 0.7 0.7 0.9
Hand grip strength (right) 0.4 1.2 6.1 0.1 -1.9 -0.2 0.5 0.7 2.1 -1.5 -1.2 -0.0 -0.1 0.1 -1.6 -2.1 -0.4 0.2 -0.3 2.5 0.3 0.0 -0.3 0.4 0.5 0.8
Townsend deprivation index at recruitment 0.1 0.1 1.2 -0.4 -0.5 -0.2 0.2 0.1 -1.1 0.2 0.4 -0.3 -0.2 -0.0 -0.1 0.1 0.0 0.3 -0.1 -0.4 -0.2 -0.2 -0.1 -0.3 -0.3 -0.6
Current tobacco smoking 0.2 0.3 2.0 -0.8 -0.3 -0.4 -0.1 -0.6 0.4 -1.4 -0.8 -0.5 0.2 -0.6 -0.3 -0.6 -0.3 -0.1 -0.3 0.0 -0.3 -0.5 -0.3 -0.4 -0.4 -0.6
Average weekly fortified wine intake 2.8 3.3 6.8 1.9 1.1 1.9 1.6 1.6 1.0 0.9 0.8 1.6 -2.0 -1.9 1.6 1.2 1.8 1.4 2.0 2.6 2.2 2.2 2.0 2.2 2.3 2.4
Maternal smoking around birth 2.7 4.0 6.9 -2.6 0.3 -2.2 -2.2 -2.4 -1.1 -1.0 -0.2 -2.0 2.3 1.8 -2.2 -2.0 -2.3 -1.9 -2.2 -1.6 -2.2 -2.2 -2.2 -2.1 -2.2 -2.1
Fed-up feelings 0.2 0.4 1.8 -0.3 0.6 0.5 1.3 0.6 0.6 0.3 0.7 1.1 -0.5 -1.3 0.5 0.8 0.5 0.0 0.5 -0.1 0.3 0.1 0.6 0.3 0.3 -0.0
Frequency of unenthusiasm / disinterest in last 2 weeks 1.1 1.5 3.9 0.7 1.8 1.1 1.3 1.1 2.0 1.4 1.3 1.4 -1.2 -1.3 1.4 1.3 1.1 0.8 1.2 0.7 1.1 1.1 1.2 1.1 1.1 1.0
Relative age voice broke 0.6 0.9 1.6 1.1 1.3 0.8 0.8 1.0 1.2 1.0 1.2 0.4 -1.0 -0.7 0.9 1.0 0.9 1.2 0.9 0.9 0.9 1.0 0.8 1.0 0.8 0.9
Taking other prescription medications 0.1 0.2 1.0 -0.4 -0.2 -0.0 -0.1 -0.3 -0.1 -0.7 -0.7 0.7 0.2 0.3 0.4 0.4 -0.0 -1.0 -0.1 -0.7 -0.2 -0.2 0.0 -0.2 -0.1 -0.0
Age when periods started (menarche) 0.6 1.4 4.0 2.0 0.4 1.5 0.9 1.0 0.1 -0.0 -0.1 1.1 -1.4 -0.7 0.8 1.2 1.4 1.4 1.4 1.5 1.4 1.4 1.3 1.4 1.3 1.3
Bilateral oophorectomy (both ovaries removed) 0.1 0.2 0.7 0.4 -0.0 0.2 0.1 0.5 -0.5 0.2 -0.2 -0.1 -0.6 -0.2 0.9 0.8 0.5 0.6 0.2 -0.3 0.2 0.3 0.2 -0.0 0.0 0.0
Heel bone mineral density (BMD) T-score, automated (left) 3.2 7.3 14.1 -2.9 -1.5 -2.5 -3.4 -3.0 -0.2 -2.3 -2.2 -2.6 3.6 3.0 -3.8 -3.5 -3.2 -3.2 -2.8 -1.3 -2.5 -2.6 -2.8 -2.3 -2.2 -1.7
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 3.0 -0.1 -1.7 -0.2 0.1 0.3 -0.5 -0.7 -1.2 -0.1 0.4 -0.3 -0.5 -1.1 -0.3 -0.2 -0.3 0.6 -0.0 -0.1 -0.3 0.0 0.2 0.3
Qualifications: CSEs or equivalent 1.3 1.7 3.9 -2.0 1.7 -1.0 -1.4 -1.7 0.7 -0.9 0.5 -1.5 1.5 1.2 -1.4 -0.8 -1.2 -0.9 -1.2 -1.3 -1.3 -1.3 -1.2 -1.3 -1.4 -1.5
Serious illness, injury or assault to yourself 0.4 0.5 1.5 0.1 1.1 0.4 0.8 0.6 1.1 1.0 1.0 1.2 -0.7 -0.7 1.1 1.2 0.5 -0.4 0.5 -0.6 0.2 0.3 0.6 0.3 0.2 0.1
High blood pressure 0.6 1.6 4.9 1.6 0.1 1.6 0.6 0.4 -1.4 0.3 0.5 1.6 -1.1 0.5 1.3 2.2 1.7 0.6 1.5 0.4 1.4 1.5 1.6 1.3 1.4 1.4
Hayfever, allergic rhinitis or eczema 4.4 9.5 13.5 3.7 1.4 3.5 3.0 3.0 2.7 1.7 1.1 3.0 -3.2 -2.5 3.0 2.8 3.2 2.8 3.5 3.6 3.6 3.5 3.4 3.6 3.5 3.7
Multivitamins +/- minerals 6.4 8.1 12.0 3.0 0.9 2.6 3.4 3.5 3.2 1.7 1.1 2.7 -3.2 -3.3 2.9 1.9 3.0 3.3 2.6 3.4 3.0 3.0 2.6 3.0 3.1 3.1
Stomach or abdominal pain in last month 0.5 0.6 1.7 -0.9 0.4 -0.7 -1.0 -1.3 -0.9 -0.4 0.0 -0.6 0.8 0.8 -0.7 -0.0 -0.6 -1.1 -0.5 -1.3 -0.8 -0.8 -0.5 -0.8 -0.8 -0.9
Supplements: Glucosamine 1.0 1.2 3.5 1.4 -1.3 0.9 1.3 1.6 0.1 0.3 -0.3 1.9 -1.5 -1.0 1.2 0.8 1.1 0.6 0.9 1.2 1.0 1.1 1.0 1.0 1.1 1.3
Diverticular disease/diverticulitis (self-reported) 2.8 3.3 4.5 -1.8 -1.4 -2.1 -1.7 -1.5 -1.6 -0.7 -1.0 -1.5 1.9 1.5 -1.8 -1.9 -2.1 -1.8 -2.1 -1.9 -2.1 -2.1 -2.1 -2.1 -2.1 -2.1
Medication: Atenolol 0.4 0.5 2.6 1.0 -1.6 0.5 0.7 0.7 -1.3 0.1 0.1 0.5 -0.9 0.1 0.2 0.3 0.7 0.8 0.6 0.7 0.7 0.7 0.6 0.7 0.8 0.7
Medication: Levothyroxine sodium 1.7 2.8 5.7 1.2 1.7 1.8 2.0 1.4 1.3 1.5 2.0 2.4 -1.8 -1.2 1.7 2.1 1.8 0.7 1.6 1.2 1.6 1.7 1.7 1.7 1.6 1.8
Sitting height 0.3 2.0 13.1 -0.7 -3.6 -0.8 -0.4 0.4 -1.0 0.8 0.3 1.4 1.0 1.5 -2.7 -2.1 -1.5 -2.4 -1.2 1.3 -0.7 -0.7 -1.0 -0.3 -0.3 0.5
Chronic bronchitis/emphysema (father) 0.5 0.6 3.5 -0.9 0.4 -0.5 -0.1 -0.7 -1.3 0.1 0.0 0.7 0.5 -0.5 0.4 0.5 -0.4 -1.9 -0.3 -1.8 -0.7 -0.8 -0.1 -0.7 -0.7 -0.8
High blood pressure (mother) 0.4 0.6 1.9 0.6 0.3 0.8 0.7 0.6 1.4 0.3 0.2 0.7 -0.8 -0.2 0.7 0.8 0.9 0.5 0.9 0.7 0.9 1.0 0.9 0.9 1.0 1.1
Body mass index (BMI) 0.7 2.9 8.8 -0.1 1.2 1.9 2.2 1.4 1.9 0.7 1.0 1.9 -1.3 -3.0 2.0 1.6 1.9 1.1 1.9 1.3 1.8 1.5 1.9 1.7 1.8 1.7
Impedance of leg (left) 2.0 9.6 16.1 -2.1 -2.0 -3.4 -3.6 -3.2 -2.8 -2.9 -2.6 -2.3 2.7 3.8 -4.0 -3.9 -3.8 -3.6 -3.3 -1.9 -3.2 -3.2 -3.3 -3.0 -3.1 -2.6
Leg predicted mass (left) 0.2 0.9 4.0 -0.5 -0.7 0.6 0.9 0.6 2.0 -0.2 -0.1 1.7 0.1 -1.1 -0.5 -0.7 0.2 -0.8 0.3 1.9 0.6 0.4 0.4 0.8 0.9 1.4
Trunk fat mass 0.2 0.7 3.5 -0.9 -0.4 0.5 1.0 0.5 1.2 -0.2 -0.0 1.9 -0.1 -1.3 -0.6 -0.7 -0.1 -1.2 0.4 1.4 0.5 0.2 0.5 0.7 0.7 1.1
Waist circumference 0.1 0.5 3.5 -1.9 -0.2 -0.4 -0.3 -0.8 0.4 -0.9 -0.4 0.3 1.0 -0.3 -0.6 -0.8 -0.6 -1.3 -0.5 -0.4 -0.5 -0.6 -0.4 -0.4 -0.4 -0.1
Number of incorrect matches in round 1.3 2.2 4.9 1.7 -0.7 1.5 1.8 1.6 -1.4 0.7 0.4 2.2 -1.9 -0.9 1.8 2.0 1.7 0.7 1.6 0.6 1.5 1.6 1.6 1.4 1.4 1.5
Past tobacco smoking 3.3 6.0 15.4 -1.6 -2.2 -2.2 -3.2 -2.6 -1.7 -2.4 -2.2 -2.5 2.6 3.9 -3.7 -3.1 -2.6 -2.1 -2.5 -0.9 -2.1 -2.1 -2.5 -2.0 -1.9 -1.4
Alcohol usually taken with meals 0.4 0.7 2.1 1.5 0.3 0.9 0.4 0.7 1.0 -0.3 -0.7 0.8 -0.9 -0.2 0.7 0.6 0.8 0.4 0.9 1.1 0.9 0.9 0.9 1.0 1.0 1.1
Nervous feelings 0.6 1.0 4.8 1.3 0.4 0.8 0.9 1.2 -0.2 1.3 1.5 0.2 -1.0 0.0 0.7 1.4 1.2 2.2 1.0 0.6 0.9 1.1 0.9 0.8 0.8 0.4
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.2 2.6 -1.6 0.2 -1.3 -1.0 -1.3 -0.3 -0.4 0.0 -0.4 1.1 1.0 -1.2 -0.8 -1.1 -1.5 -1.2 -1.1 -1.3 -1.3 -1.1 -1.3 -1.2 -1.3
Hearing difficulty/problems with background noise 0.3 0.4 2.0 -0.9 1.0 0.0 0.0 -0.2 -0.4 0.7 1.0 0.3 -0.3 -0.7 1.4 1.2 0.2 -0.4 0.2 -1.4 -0.1 0.1 0.2 -0.2 -0.2 -0.3
Hair/balding pattern: Pattern 2 0.5 0.6 2.0 -1.4 -0.3 -0.9 -0.6 -0.8 -0.0 -0.9 -0.4 -0.4 0.7 0.4 -0.8 -1.1 -0.9 -0.6 -0.9 -0.3 -0.8 -0.9 -0.9 -0.8 -0.8 -0.8
Had menopause 0.9 1.2 2.5 0.5 1.0 1.0 1.0 0.9 0.6 1.3 1.2 1.6 -1.2 -1.4 1.6 1.4 1.1 0.2 1.0 0.7 1.0 1.1 1.0 1.0 1.0 1.1
Had other major operations 0.8 1.0 2.6 1.0 0.8 1.1 1.1 0.6 -0.1 0.5 0.8 1.4 -1.2 -0.9 1.4 1.6 1.3 0.9 1.1 0.1 1.0 1.0 1.1 0.9 0.8 0.7
Forced vital capacity (FVC) 1.0 3.8 9.2 -1.0 -2.3 -2.1 -2.0 -1.5 -0.6 -1.6 -1.3 -2.0 2.2 2.5 -2.8 -3.0 -2.3 -1.3 -2.3 -0.2 -1.9 -1.9 -2.4 -1.7 -1.7 -1.4
Heel bone mineral density (BMD) T-score, automated (right) 5.9 13.5 23.0 -3.5 -2.5 -3.6 -4.6 -4.0 -1.9 -3.0 -3.0 -3.5 4.8 4.3 -4.8 -4.3 -4.2 -4.1 -3.8 -2.3 -3.6 -3.6 -3.8 -3.4 -3.3 -2.7
Ever unenthusiastic/disinterested for a whole week 6.0 7.3 16.7 1.9 4.1 2.7 2.4 1.9 3.1 2.3 2.8 1.9 -2.4 -3.0 3.1 3.1 2.8 2.5 2.8 2.1 2.7 2.7 2.9 2.7 2.6 2.3
Qualifications: None of the above 1.5 3.3 11.6 1.2 0.7 1.7 2.5 2.0 -0.0 1.2 0.7 1.8 -2.0 -3.4 2.9 2.1 2.2 1.9 1.9 0.4 1.7 1.5 1.9 1.5 1.5 1.0
Financial difficulties in last 2 years 0.1 0.2 0.9 -0.5 0.1 -0.0 0.0 -0.3 0.5 -0.9 -0.9 0.5 0.1 -0.4 -0.3 -0.6 -0.2 -0.8 -0.0 0.6 0.0 -0.1 0.0 0.1 0.2 0.3
Mouth/teeth dental problems 0.8 1.2 3.5 -0.4 -1.2 -1.1 -1.0 -0.7 -0.9 -1.1 -0.9 -1.0 1.1 1.9 -1.7 -1.6 -1.3 -0.6 -1.2 -0.1 -1.1 -1.0 -1.3 -1.0 -1.0 -0.9
Heart attack 2.6 3.4 5.3 -1.7 -2.3 -1.8 -2.0 -1.9 -1.9 -2.0 -2.3 -1.3 1.8 1.8 -1.6 -1.6 -1.6 -2.2 -1.6 -2.1 -1.7 -1.8 -1.6 -1.8 -1.6 -1.5
Allergy 3.7 8.5 12.7 -3.2 -1.5 -3.4 -2.7 -2.6 -3.0 -1.9 -0.9 -2.5 2.8 3.2 -3.0 -2.5 -3.0 -2.5 -3.2 -3.3 -3.3 -3.3 -3.2 -3.4 -3.4 -3.6
Pain all over the body in last month 1.6 1.7 2.8 1.1 1.2 1.3 1.6 1.1 1.0 1.3 1.5 1.7 -1.5 -1.1 1.3 1.5 1.3 0.9 1.4 0.7 1.2 1.2 1.4 1.3 1.3 1.1
Diabetes (self-reported) 2.1 3.3 5.4 -1.9 -1.6 -1.9 -2.1 -2.2 -2.2 -2.2 -1.8 -2.3 2.0 2.0 -1.7 -1.6 -1.5 -1.3 -1.8 -1.5 -1.7 -1.6 -1.7 -1.8 -1.5 -1.5
Hayfever/allergic rhinitis (self-reported) 1.7 2.2 3.6 1.9 1.1 1.7 1.5 1.7 1.3 1.6 1.0 1.3 -1.7 -1.0 1.6 1.8 1.5 1.4 1.7 1.0 1.6 1.6 1.7 1.5 1.4 1.3
Medication: Ramipril 0.4 0.5 1.3 0.8 0.0 0.6 0.2 -0.1 -0.4 -1.1 -0.8 0.1 -0.5 -0.3 0.9 0.8 1.1 1.0 0.8 0.4 0.8 0.8 0.8 0.6 0.8 0.6
Medication: Simvastatin 0.4 0.6 2.4 -0.7 -0.6 -0.6 -0.9 -0.9 -1.5 -0.4 -0.5 -0.7 0.7 1.1 -0.3 0.2 -0.2 -0.5 -0.5 -1.5 -0.7 -0.6 -0.5 -0.9 -0.7 -1.0
Fluid intelligence score 0.6 1.2 3.7 1.9 0.6 1.0 0.5 1.0 -0.3 1.7 1.1 0.4 -1.1 0.1 1.2 1.8 1.3 1.2 1.1 0.4 0.9 1.2 1.1 0.9 0.9 0.7
Illnesses of siblings 0.5 0.7 3.8 -0.1 -1.9 -0.7 -0.6 -0.2 -0.4 -0.6 -1.3 -0.7 0.5 0.2 -1.3 -1.6 -1.1 -0.6 -0.8 -0.1 -0.7 -0.8 -0.9 -0.6 -0.7 -0.5
Neuroticism score 0.2 0.4 1.3 0.3 0.0 0.4 1.0 0.6 -1.1 0.6 1.1 0.6 -0.7 -0.3 0.5 1.1 0.7 0.8 0.6 -0.2 0.3 0.3 0.6 0.3 0.2 -0.2
Weight 0.2 0.8 2.2 -1.4 -1.0 0.2 0.6 0.1 1.5 -0.9 -0.4 1.4 0.4 -0.9 -0.8 -1.2 -0.3 -1.3 -0.1 1.5 0.3 -0.1 0.1 0.4 0.5 1.1
Impedance of arm (right) 0.4 1.9 6.1 -0.3 -1.2 -1.6 -1.3 -0.7 -1.3 0.3 -0.3 -0.8 1.0 2.1 -2.5 -2.0 -2.1 -1.5 -1.4 -0.5 -1.4 -1.4 -1.5 -1.2 -1.3 -1.1
Arm fat percentage (right) 0.5 2.2 6.4 0.0 0.7 1.6 2.1 1.5 1.5 1.1 1.2 1.8 -1.2 -2.5 1.3 1.1 1.4 0.8 1.6 1.3 1.5 1.3 1.6 1.5 1.5 1.4
Trunk fat-free mass 0.2 0.9 3.3 -1.0 -1.3 -0.1 -0.0 -0.2 1.5 -1.6 -0.9 1.0 0.9 -0.1 -1.3 -1.7 -0.5 -1.2 -0.5 1.8 0.0 -0.2 -0.4 0.2 0.3 1.0
Hip circumference 1.5 6.5 11.5 1.5 0.4 2.8 3.1 2.8 2.7 1.2 0.9 3.3 -2.2 -3.2 2.0 1.6 2.5 1.5 2.6 3.4 2.9 2.7 2.7 2.9 2.9 3.3
Time employed in main current job 0.3 0.4 0.9 0.9 0.1 0.9 0.4 0.5 0.5 0.2 -0.0 0.4 -0.4 -0.3 0.6 0.8 0.7 0.7 0.9 0.2 0.7 0.6 0.8 0.7 0.6 0.5
Alcohol intake versus 10 years previously 0.9 1.4 3.7 0.8 0.6 1.1 1.7 1.4 1.9 0.7 0.5 1.6 -1.3 -1.3 0.9 0.9 1.2 0.7 1.2 0.9 1.2 1.0 1.3 1.2 1.3 1.0
Father’s age at death 0.3 0.4 1.9 0.4 1.2 0.5 0.1 0.0 1.4 0.2 0.4 -0.3 -0.1 -0.4 0.6 1.0 0.8 0.9 0.5 -0.0 0.4 0.5 0.5 0.3 0.3 0.1
Worrier / anxious feelings 0.8 1.4 2.9 -1.0 -0.7 -1.2 -1.1 -1.1 -1.5 -0.4 -0.4 -0.1 1.5 1.7 -1.2 -0.9 -1.3 -1.6 -1.1 -1.2 -1.3 -1.4 -1.1 -1.2 -1.3 -1.3
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.5 1.4 -0.6 1.1 -0.9 -0.9 -1.2 0.3 -0.5 0.1 -0.4 0.6 0.4 -0.6 -0.5 -0.7 -0.7 -0.6 -0.4 -0.7 -0.6 -0.6 -0.7 -0.7 -0.7
Falls in the last year 0.2 0.3 1.6 -0.8 1.2 -0.0 0.5 -0.1 0.7 0.2 1.1 0.6 -0.2 -1.1 0.9 0.4 0.0 -0.1 0.1 -0.4 -0.1 0.1 0.1 -0.1 -0.0 -0.1
Hair/balding pattern: Pattern 3 0.2 0.2 1.4 0.3 0.1 -0.2 -0.9 -0.6 0.4 -0.5 -0.9 -1.2 0.7 0.3 -0.3 -0.6 -0.4 -0.0 -0.3 0.1 -0.2 -0.3 -0.3 -0.2 -0.1 -0.1
Number of live births 0.6 0.8 2.5 -1.5 -1.0 -0.8 -0.6 -0.6 -1.1 -0.3 -0.6 -0.6 0.8 -0.4 -0.2 -0.3 -0.6 -1.2 -0.9 -1.6 -1.0 -1.1 -0.8 -1.1 -1.0 -1.0
Forced expiratory volume in 1-second (FEV1) 1.6 5.3 10.0 -1.6 -2.3 -2.6 -2.7 -2.0 -0.1 -2.0 -1.9 -2.6 2.6 2.6 -3.0 -3.2 -2.5 -1.7 -2.7 -0.9 -2.4 -2.4 -2.7 -2.2 -2.2 -1.9
Pulse rate 4.9 8.3 13.7 -3.1 -1.7 -3.1 -3.0 -2.8 -1.9 -1.9 -1.6 -2.3 3.0 3.4 -3.7 -3.3 -3.3 -3.3 -3.2 -2.4 -3.1 -3.2 -3.2 -3.0 -3.0 -2.7
Happiness 1.6 1.9 4.4 -1.7 0.1 -1.4 -1.3 -1.8 0.5 -1.7 -0.0 -1.8 1.4 2.1 -2.0 -1.8 -1.5 -0.6 -1.5 0.0 -1.3 -1.2 -1.5 -1.2 -1.3 -1.1
Noisy workplace 0.2 0.3 1.2 -0.7 -0.6 -0.7 0.0 0.0 0.2 -0.7 -1.1 -0.1 0.1 -0.1 0.1 -0.9 -0.6 -0.1 -0.6 -0.4 -0.5 -0.6 -0.7 -0.6 -0.5 -0.6
Qualifications: A levels/AS levels or equivalent 0.2 0.5 3.8 1.0 0.2 0.5 -0.4 -0.0 1.9 -0.0 -0.4 0.4 -0.4 0.9 0.1 0.6 0.6 0.1 0.4 0.9 0.6 0.7 0.5 0.6 0.5 1.0
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 1.4 0.3 0.8 0.4 0.5 -0.1 0.9 0.4 1.2 -0.1 -0.6 0.2 0.1 0.6 0.7 1.0 0.4 0.2 0.4 0.5 0.4 0.3 0.4 0.3
Mouth/teeth dental problems: Dentures 0.1 0.2 0.9 0.1 -0.4 0.5 0.3 0.1 0.4 0.0 -0.7 0.5 -0.1 -1.0 0.3 0.1 0.3 -0.1 0.5 0.3 0.5 0.3 0.5 0.5 0.4 0.6
Asthma 0.8 1.7 5.2 0.9 0.9 1.4 1.3 0.8 1.6 0.0 -0.2 0.8 -1.1 -2.3 1.8 0.9 1.4 1.3 1.3 1.2 1.4 1.3 1.3 1.4 1.4 1.5
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.3 1.7 -0.8 -0.4 -0.2 0.5 -0.3 -0.5 -1.3 -0.9 0.6 0.2 -0.7 0.2 0.1 0.1 -1.0 -0.2 -0.6 -0.2 -0.4 -0.0 -0.4 -0.3 -0.3
Medication: Cholesterol lowering 0.2 0.4 1.7 -0.3 -0.2 -0.1 -0.9 -0.9 -1.3 -0.6 -0.8 0.3 0.5 0.9 -0.0 0.6 0.2 -1.0 0.0 -1.0 -0.2 -0.2 0.1 -0.3 -0.2 -0.1
Depression (self-reported) 5.3 6.3 8.5 2.0 2.1 2.7 2.4 2.4 2.5 2.8 2.8 2.5 -2.0 -2.3 2.0 2.5 2.4 2.1 2.6 2.9 2.6 2.8 2.6 2.8 2.7 2.9
Medication: Lansoprazole 9.2 10.4 13.8 -3.0 -1.4 -3.5 -3.5 -3.4 -1.9 -2.6 -2.3 -2.6 3.3 3.6 -3.0 -3.0 -3.6 -3.5 -3.6 -3.7 -3.6 -3.5 -3.6 -3.7 -3.6 -3.5
Prospective memory result 0.5 0.6 1.4 -1.0 -0.6 -0.9 -0.5 -0.6 -0.1 -0.9 -0.6 -1.0 0.7 0.5 -1.1 -1.2 -1.0 -0.1 -0.9 -0.5 -0.8 -0.9 -1.0 -0.8 -0.8 -0.9
Lung cancer (father) 0.2 0.2 1.1 -0.3 0.8 -0.2 0.1 0.2 0.5 1.1 0.8 0.3 -0.3 -0.2 0.1 0.3 -0.2 -0.5 -0.1 -0.7 -0.3 -0.2 -0.1 -0.3 -0.3 -0.4
Illnesses of mother 0.2 0.2 1.0 -0.5 0.6 -0.3 -0.1 -0.1 0.3 0.2 0.8 -1.0 0.2 -0.6 -0.4 -0.6 -0.5 0.5 -0.5 0.3 -0.4 -0.4 -0.5 -0.3 -0.4 -0.6
Forced expiratory volume in 1-second (FEV1), Best measure 2.2 7.0 13.6 -2.2 -1.7 -3.0 -3.0 -2.4 -0.0 -2.0 -1.5 -3.2 2.9 2.9 -3.5 -3.7 -3.1 -1.9 -3.2 -1.2 -2.8 -2.8 -3.2 -2.6 -2.6 -2.4
Pulse wave Arterial Stiffness index 0.6 0.7 2.3 -0.5 -0.1 -0.6 -1.3 -1.4 -1.1 -1.4 -1.2 -0.2 0.7 0.9 -0.8 -0.6 -0.6 -1.5 -0.6 -0.4 -0.5 -0.5 -0.5 -0.5 -0.4 -0.0
Impedance of arm (left) 0.6 2.6 7.5 -0.7 -1.4 -1.8 -1.6 -1.1 -1.2 0.0 -0.5 -1.0 1.3 2.4 -2.7 -2.1 -2.3 -1.8 -1.7 -0.9 -1.8 -1.7 -1.8 -1.5 -1.7 -1.5
Arm fat mass (right) 0.3 1.3 4.3 -0.5 0.0 1.2 1.6 1.0 1.6 0.3 0.5 1.9 -0.6 -2.1 0.5 0.3 0.9 -0.0 1.0 1.5 1.1 0.9 1.1 1.2 1.3 1.5
Trunk predicted mass 0.2 1.1 3.5 -1.2 -1.4 -0.3 -0.2 -0.4 1.4 -1.8 -1.1 0.8 1.1 0.1 -1.5 -1.9 -0.7 -1.4 -0.7 1.6 -0.2 -0.4 -0.6 -0.0 0.1 0.8
Standing height 1.4 13.7 37.5 -3.0 -4.6 -3.6 -3.5 -2.8 -0.9 -3.6 -3.0 -0.8 3.7 4.1 -6.1 -6.1 -4.6 -5.3 -4.2 0.5 -3.3 -3.5 -4.0 -2.8 -2.7 -1.3
Length of working week for main job 0.3 0.3 2.8 -0.3 -1.3 -0.2 -0.4 -0.5 -1.7 -0.9 -0.8 -0.5 0.3 -0.2 -0.2 -0.5 -0.1 0.3 -0.2 0.1 -0.1 -0.2 -0.2 -0.2 -0.1 -0.2
Exposure to tobacco smoke at home 0.9 1.0 2.0 1.4 -1.2 1.2 0.6 0.6 -0.2 -1.1 -1.4 1.0 -0.9 0.0 0.6 0.6 1.1 0.9 1.0 1.2 1.1 1.0 1.0 1.0 1.0 1.1
Breastfed as a baby 2.1 2.6 5.1 1.8 1.7 1.3 1.6 1.9 1.1 2.0 1.7 1.6 -1.8 -1.5 1.6 1.1 1.4 1.4 1.4 2.3 1.5 1.7 1.4 1.7 1.5 1.6
Tense / ‘highly strung’ 0.2 0.3 2.2 0.0 0.6 -0.3 -0.3 -0.6 -1.5 -0.2 0.7 -0.2 0.2 1.4 -0.7 0.4 -0.0 -0.2 -0.1 -0.5 -0.4 -0.3 -0.1 -0.4 -0.5 -0.7
Seen doctor (GP) for nerves, anxiety, tension or depression 3.2 4.8 10.8 1.2 3.0 2.1 2.4 1.9 1.2 2.6 3.3 2.5 -2.2 -2.4 2.6 2.8 2.2 1.3 2.2 1.3 1.9 2.0 2.3 2.0 1.9 1.7
Hair/balding pattern: Pattern 4 1.8 4.3 5.8 1.9 1.8 2.2 2.2 2.0 1.0 2.0 1.9 2.2 -1.8 -2.0 2.1 2.3 2.2 1.7 2.4 2.0 2.2 2.3 2.4 2.3 2.3 2.1
Birth weight of first child 0.9 1.6 4.1 0.9 -1.4 1.1 1.6 2.0 1.7 0.8 -0.2 1.4 -1.4 -1.9 0.7 -0.0 0.8 0.6 0.8 1.8 1.2 1.2 0.8 1.3 1.3 1.8
Peak expiratory flow (PEF) 0.3 0.7 3.7 1.5 -0.8 0.8 0.5 1.0 1.9 0.5 -0.4 0.3 -0.8 -0.4 0.6 0.6 1.0 0.8 0.6 0.6 0.8 0.8 0.7 0.9 0.9 1.0
Pulse wave reflection index 3.1 3.8 7.0 1.5 1.9 2.0 2.1 1.7 1.2 1.0 1.4 1.6 -2.1 -2.5 2.6 2.0 2.2 2.0 2.0 1.9 2.1 2.2 2.0 2.0 2.1 2.0
Ever highly irritable/argumentative for 2 days 1.4 1.7 4.0 0.5 1.7 1.0 1.6 1.3 1.6 1.4 2.0 0.9 -1.7 -1.3 1.3 0.7 1.0 1.5 1.1 1.6 1.2 1.3 1.1 1.3 1.2 1.1
Loud music exposure frequency 0.7 0.8 6.5 -1.4 2.5 -0.8 -0.3 -0.6 1.3 -0.2 1.0 -0.5 0.5 0.1 -0.2 0.0 -0.6 -0.3 -0.6 -0.7 -0.9 -0.7 -0.6 -0.8 -1.0 -1.2
Qualifications: O levels/GCSEs or equivalent 1.6 2.6 6.0 -1.4 0.8 -1.5 -2.0 -2.2 1.9 -1.6 -0.9 -1.2 1.6 2.5 -1.9 -1.7 -1.7 -1.8 -1.7 -0.8 -1.6 -1.5 -1.6 -1.4 -1.5 -1.2
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 3.8 0.1 1.9 0.6 -0.1 -0.4 0.9 -0.3 0.4 -0.0 -0.3 -0.4 0.8 0.8 0.6 0.3 0.6 0.3 0.5 0.5 0.6 0.5 0.4 0.4
Blood clot in the leg (DVT) 0.2 0.2 0.8 0.3 0.9 0.2 -0.3 -0.1 0.9 0.8 0.0 -0.3 0.2 -0.8 0.8 0.5 0.3 0.0 0.2 -0.4 0.1 0.2 0.3 0.1 0.2 0.1
Medication: Paracetamol 0.3 0.6 2.8 0.0 -1.4 -0.1 0.6 0.5 0.1 -0.3 -1.7 1.6 -0.3 -1.4 0.6 -0.3 -0.1 -1.5 -0.1 -0.4 -0.1 -0.3 0.0 -0.1 0.0 0.3
Headache pain in last month 0.5 0.9 2.9 -1.5 1.7 -1.0 -1.1 -1.2 0.1 -0.1 0.5 -1.0 0.8 -0.0 -0.1 -0.3 -0.9 -1.1 -0.9 -1.2 -1.1 -0.9 -0.9 -1.0 -1.1 -1.0
Medication for cholesterol, blood pressure or diabetes 0.3 0.4 4.3 -0.1 0.7 -0.0 0.7 0.6 2.1 0.7 0.8 -0.4 -0.3 -1.2 0.1 -0.6 -0.3 0.4 -0.2 0.6 -0.1 -0.1 -0.3 0.1 -0.0 0.1
Glaucoma (self-reported) 0.1 0.1 0.7 -0.1 0.5 0.0 0.2 0.0 0.4 0.4 0.2 0.6 -0.2 0.5 0.3 0.8 0.3 -0.3 0.2 -0.8 -0.0 0.1 0.3 -0.1 0.0 -0.1
Gout (self-reported) 0.7 1.0 2.0 -0.9 -1.1 -1.1 -0.8 -0.6 -0.4 -1.3 -1.4 -0.7 1.1 1.2 -1.2 -1.1 -0.9 -0.5 -1.0 -0.5 -1.0 -1.0 -1.0 -1.0 -1.0 -1.0
Hypothyroidism/myxoedema (self-reported) 1.1 2.1 5.5 1.0 1.9 1.5 1.6 1.1 0.8 1.4 1.8 2.3 -1.5 -0.8 1.9 2.3 1.6 0.4 1.4 0.6 1.3 1.4 1.5 1.3 1.2 1.4
Medication: Amlodipine 0.5 0.7 3.0 0.6 -0.9 1.0 0.6 0.4 -1.5 -0.2 -0.6 1.7 -0.3 0.1 0.9 1.2 0.7 -0.5 0.8 -0.3 0.7 0.6 0.9 0.6 0.6 0.8
Medication: Ventolin 100micrograms inhaler 0.3 0.4 1.1 0.6 0.7 0.8 0.4 0.2 1.0 -0.4 -0.6 0.2 -0.3 -0.8 0.8 0.7 0.8 0.6 0.8 0.3 0.8 0.6 0.8 0.7 0.7 0.7
Birth weight 3.1 6.7 13.4 2.7 0.4 2.4 2.9 3.2 3.2 1.2 0.1 2.6 -3.0 -3.7 2.6 1.4 2.4 2.2 2.5 3.5 2.7 2.6 2.5 2.8 2.8 2.9
Chronic bronchitis/emphysema (mother) 1.0 1.2 2.1 -1.4 0.2 -1.3 -0.5 -0.8 -0.0 -0.6 0.0 -0.9 0.8 0.9 -1.0 -1.5 -1.5 -1.1 -1.3 -1.2 -1.3 -1.4 -1.4 -1.3 -1.3 -1.4
High blood pressure (siblings) 0.2 0.3 1.4 0.0 1.2 0.5 0.6 0.3 0.7 0.4 0.9 0.7 -0.2 -0.1 0.7 0.6 0.6 0.3 0.5 0.5 0.5 0.6 0.5 0.5 0.6 0.6
Forced vital capacity (FVC), Best measure 1.8 6.6 14.0 -2.0 -1.8 -2.9 -2.8 -2.3 -0.4 -2.0 -1.4 -2.8 2.8 3.0 -3.5 -3.7 -3.1 -2.0 -3.1 -0.9 -2.7 -2.7 -3.1 -2.5 -2.5 -2.2
Body fat percentage 0.2 0.7 2.9 -0.6 0.2 0.8 1.2 0.7 0.9 0.3 0.4 1.7 -0.5 -1.7 0.2 0.0 0.4 -0.6 0.8 1.0 0.8 0.5 0.8 0.9 0.9 1.0
Leg fat percentage (right) 0.2 0.9 3.3 -0.3 0.8 1.1 1.3 0.7 0.9 0.1 0.3 1.6 -0.6 -1.8 0.7 0.3 0.6 -0.3 1.0 1.0 1.0 0.7 1.1 1.1 1.0 1.2
Arm fat-free mass (right) 0.3 1.3 3.9 -1.6 -1.4 -0.5 -0.4 -0.8 1.4 -1.9 -1.3 0.8 1.1 0.1 -1.6 -2.0 -0.9 -2.0 -0.9 1.2 -0.4 -0.7 -0.7 -0.2 -0.1 0.5
Exposure to tobacco smoke outside home 0.1 0.2 1.7 0.1 1.3 0.1 -0.5 -0.7 0.2 -0.6 -0.3 0.1 0.2 0.3 -0.0 0.5 0.1 -0.5 0.2 -0.1 0.1 0.1 0.3 0.1 0.0 0.1
Comparative body size at age 10 3.6 9.9 21.3 2.1 1.9 3.2 3.7 3.3 3.1 2.1 2.1 2.0 -3.3 -4.6 3.8 3.2 3.5 4.0 3.4 2.7 3.3 3.2 3.3 3.1 3.2 2.6
Number of full brothers 0.3 0.4 2.3 -1.2 1.5 -0.6 -0.3 -0.7 -0.3 0.1 0.8 -0.2 0.3 -0.0 -0.3 -0.1 -0.5 -0.8 -0.5 -0.7 -0.7 -0.6 -0.4 -0.6 -0.7 -0.7
Worry too long after embarrassment 1.9 3.3 10.6 -1.9 -0.5 -1.9 -1.5 -1.9 -3.3 -0.6 0.2 -1.5 2.0 1.8 -1.2 -1.1 -1.7 -1.3 -1.9 -2.4 -2.0 -1.9 -1.9 -2.1 -2.1 -2.3
Seen a psychiatrist for nerves, anxiety, tension or depression 1.6 2.1 9.1 0.6 2.1 1.2 1.6 1.1 1.7 2.0 3.0 1.0 -1.4 -1.0 0.9 1.5 1.2 1.5 1.3 1.4 1.2 1.3 1.3 1.3 1.2 1.0
Wheeze or whistling in the chest in last year 0.9 1.6 5.7 0.2 1.0 1.4 1.4 0.8 1.2 0.3 0.3 1.6 -1.0 -2.4 1.8 1.1 1.2 0.4 1.3 0.8 1.3 1.2 1.4 1.3 1.4 1.5
Number of children fathered 0.4 0.4 1.6 -0.1 -0.2 -0.3 -1.1 -1.0 -0.9 -1.2 -1.3 -1.1 0.6 0.4 -0.3 -0.4 -0.3 -0.1 -0.4 -0.3 -0.4 -0.5 -0.4 -0.5 -0.4 -0.5
Reason for reducing amount of alcohol drunk: Health precaution 0.1 0.1 0.8 -0.2 0.4 0.0 0.1 0.1 0.4 0.9 0.7 0.8 0.1 -0.2 0.1 0.2 0.1 -0.4 0.1 0.2 0.1 0.1 0.2 0.2 0.2 0.2
Age at first live birth 0.4 0.6 3.2 0.3 -0.9 -0.5 -1.0 -0.4 0.8 -0.7 -0.9 -0.7 0.7 1.8 -1.7 -1.1 -0.7 -0.5 -0.5 0.8 -0.2 -0.2 -0.5 -0.2 -0.1 0.2
Pulse wave peak to peak time 0.2 0.2 1.1 0.2 -0.4 0.2 0.9 1.1 0.9 0.9 0.6 0.0 -0.3 -0.4 0.3 0.0 0.2 1.0 0.2 0.2 0.1 0.1 0.1 0.1 0.1 -0.2
Health satisfaction 0.1 0.1 0.8 -0.6 -0.4 -0.1 0.3 -0.0 0.2 -0.9 -0.0 0.2 -0.7 -0.0 -0.0 -0.2 0.2 0.0 0.1 0.7 0.2 0.1 0.1 0.1 0.3 0.3
Shortness of breath walking on level ground 0.3 0.3 1.6 -0.7 0.5 -0.3 0.7 0.0 -0.1 0.4 0.4 1.1 0.2 -1.3 0.5 0.2 -0.2 -1.1 -0.1 -0.6 -0.3 -0.4 -0.1 -0.3 -0.3 -0.4
Qualifications: College or University degree 2.3 7.3 19.9 -2.4 0.1 -3.0 -3.7 -3.0 0.1 -1.1 -0.7 -3.4 2.7 4.5 -3.0 -2.1 -2.6 -2.2 -3.0 -2.5 -2.9 -2.6 -2.9 -2.9 -2.8 -2.8
Eye problems/disorders: None of the above 0.1 0.2 0.7 0.2 0.2 -0.0 0.2 0.2 -0.1 0.6 0.3 0.7 0.3 -0.2 -0.7 -0.7 -0.7 -0.8 0.0 0.6 -0.2 -0.4 0.0 0.1 -0.0 -0.2
Mouth/teeth dental problems: Loose teeth 0.3 0.4 1.6 -1.0 -0.7 -0.5 -0.3 -0.4 -0.1 -1.3 -0.6 -0.4 0.5 0.0 -0.5 -1.2 -0.5 -0.2 -0.6 0.4 -0.3 -0.4 -0.7 -0.3 -0.3 -0.0
Emphysema/chronic bronchitis 0.5 0.5 1.4 0.2 1.1 0.8 0.6 0.2 0.1 0.5 0.8 0.8 -0.5 -1.2 0.4 0.7 0.6 0.0 0.8 0.8 0.8 0.7 0.9 0.8 0.8 0.9
Medication for pain relief, constipation, heartburn 0.6 0.9 4.1 0.4 2.0 0.0 -0.5 0.0 1.4 1.1 1.9 -1.6 -0.2 1.1 -0.7 -0.6 -0.2 1.9 -0.1 1.4 0.2 0.4 -0.3 0.3 0.1 0.1
Neck or shoulder pain in last month 0.9 1.2 2.4 -1.2 -0.1 -1.1 -1.4 -1.6 -1.2 -1.3 -1.0 -1.0 1.5 0.4 -0.9 -1.2 -1.3 -1.3 -1.1 -0.6 -1.1 -1.1 -1.0 -1.0 -0.9 -0.9
Medication: Blood pressure 0.3 0.6 4.7 0.7 -1.1 0.2 -0.3 -0.2 -2.2 -1.1 -1.2 0.9 -0.1 1.3 0.3 0.9 0.6 -0.4 0.4 -0.5 0.2 0.3 0.5 0.0 0.2 0.1
Angina (self-reported) 1.5 2.0 4.2 -1.8 -1.6 -1.1 -1.6 -1.8 -1.4 -1.4 -1.3 -0.6 1.9 1.2 -1.4 -1.1 -1.3 -2.1 -1.2 -1.7 -1.2 -1.3 -1.2 -1.3 -1.2 -0.9
Migraine (self-reported) 0.7 0.9 9.2 -0.5 2.0 0.2 0.4 0.5 3.0 1.2 0.9 0.4 -0.3 -1.5 1.0 0.6 0.4 0.1 0.2 0.1 0.2 0.4 0.3 0.3 0.3 0.3
Medication: Ibuprofen 0.5 0.6 2.0 0.1 0.2 0.7 1.3 0.6 0.3 -0.4 -0.1 1.3 -0.7 -1.4 1.1 1.2 1.1 -0.1 0.8 -0.1 0.7 0.5 0.9 0.5 0.6 0.6
Medication: Allopurinol 1.1 1.5 4.4 -1.0 -1.7 -1.2 -0.8 -0.6 -0.6 -2.1 -1.8 -0.9 1.1 1.7 -1.8 -1.6 -1.0 -0.1 -1.2 0.1 -1.0 -1.1 -1.2 -1.1 -1.1 -1.1
Medication: Omeprazole 0.5 0.6 1.8 0.7 -0.3 0.7 1.1 0.7 0.3 0.0 -0.1 0.7 -0.6 -1.3 1.0 1.0 1.0 0.9 1.0 0.3 0.9 0.8 1.0 0.8 0.8 0.6
Medication: Seretide 50 evohaler 1.7 2.0 4.8 1.1 0.2 1.3 2.0 1.7 1.4 0.3 -0.2 1.5 -1.7 -2.2 1.9 0.9 1.3 1.4 1.4 1.5 1.5 1.4 1.3 1.4 1.4 1.4
Mean time to correctly identify matches 7.4 14.1 22.4 -3.5 -1.2 -4.1 -3.9 -4.0 -3.6 -3.2 -2.6 -3.1 3.6 4.0 -3.1 -2.7 -3.9 -3.7 -3.8 -4.7 -4.2 -4.2 -3.8 -4.4 -4.5 -4.6
Heart disease (mother) 0.4 0.4 2.7 -0.1 -0.4 -0.1 -0.4 -0.5 -1.4 -0.1 -0.8 0.9 0.5 0.5 0.3 0.5 -0.3 -1.6 -0.1 -1.5 -0.3 -0.3 0.0 -0.4 -0.3 -0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.2 1.0 0.0 -0.6 0.4 0.8 0.5 -0.2 -0.1 -0.0 0.1 -1.0 -0.8 1.0 0.5 0.5 0.5 0.3 -0.3 0.3 0.3 0.3 0.2 0.2 0.2
Whole body fat mass 0.2 0.7 3.3 -0.9 -0.5 0.6 1.0 0.5 1.1 -0.3 -0.2 1.8 -0.1 -1.4 -0.3 -0.5 0.1 -1.1 0.4 1.2 0.6 0.2 0.5 0.7 0.7 1.1
Leg fat mass (right) 0.2 0.6 2.5 -1.0 0.0 0.6 0.9 0.3 1.3 -0.6 -0.3 1.5 -0.0 -1.6 -0.0 -0.4 0.2 -0.9 0.5 1.1 0.6 0.2 0.6 0.7 0.7 1.0
Arm predicted mass (right) 0.3 1.5 5.5 -1.6 -1.7 -0.6 -0.4 -0.8 1.0 -2.3 -1.7 0.8 1.1 0.1 -1.6 -2.0 -0.9 -2.0 -1.0 1.0 -0.5 -0.8 -0.8 -0.4 -0.2 0.4
Pulse rate, automated reading 2.3 7.5 16.4 -1.8 -2.8 -2.5 -3.0 -2.5 -3.4 -2.0 -2.2 -1.5 3.0 4.0 -3.9 -2.7 -2.8 -3.4 -2.6 -2.3 -2.6 -2.8 -2.6 -2.5 -2.5 -2.1
Alcohol intake frequency. 0.1 0.2 0.9 -0.9 0.1 -0.2 -0.0 -0.2 0.5 0.3 0.7 -0.6 0.5 0.6 -0.9 -0.8 -0.4 -0.1 -0.5 0.1 -0.3 -0.3 -0.5 -0.2 -0.2 -0.1
Comparative height size at age 10 1.9 10.5 29.4 -3.0 -4.7 -3.1 -2.7 -2.5 -1.6 -3.7 -3.3 -1.0 3.2 2.8 -4.8 -5.4 -3.9 -4.4 -3.5 0.4 -2.8 -3.1 -3.4 -2.5 -2.4 -1.4
Number of full sisters 0.7 0.8 7.2 -0.2 2.7 0.5 0.7 -0.2 0.7 0.7 1.4 0.8 -0.4 -1.6 1.4 1.1 0.6 -0.0 0.5 -0.2 0.4 0.4 0.5 0.4 0.2 0.4
Suffer from ‘nerves’ 2.1 3.4 8.4 1.9 1.3 1.9 2.1 1.8 0.0 2.3 2.4 1.8 -1.9 -1.1 1.9 2.9 2.2 2.0 2.1 0.5 1.7 1.8 2.1 1.6 1.6 1.1
Overall health rating 0.8 1.8 5.1 -2.2 0.2 -1.4 -0.9 -1.7 -0.3 -1.2 -1.0 0.2 1.4 0.2 -0.5 -0.7 -1.2 -2.2 -1.3 -2.0 -1.5 -1.6 -1.1 -1.5 -1.4 -1.5
Chest pain or discomfort 0.3 0.5 1.8 -0.5 0.2 -0.4 -1.0 -1.3 -1.2 -0.3 -0.4 0.1 1.3 0.4 -0.4 0.0 -0.4 -1.3 -0.5 -1.1 -0.5 -0.5 -0.4 -0.5 -0.4 -0.2
Had major operations 0.3 0.3 1.7 0.6 -0.3 0.5 0.2 -0.0 -0.8 -0.3 -0.8 0.5 -0.3 -0.5 1.3 1.1 0.7 -0.3 0.4 -0.9 0.3 0.3 0.5 0.2 0.3 0.3
Age at last live birth 0.3 0.4 2.0 0.2 0.2 -0.2 -0.2 0.6 1.1 1.4 1.2 -0.5 0.2 1.0 -1.3 -0.6 -0.5 0.0 -0.2 0.8 -0.1 -0.0 -0.3 0.1 -0.0 0.1
Family relationship satisfaction 0.4 0.5 1.0 -1.0 0.6 -0.6 -0.4 -1.0 0.2 -0.9 0.6 -0.8 0.6 0.9 -1.0 -0.8 -0.7 -0.1 -0.7 0.2 -0.6 -0.6 -0.7 -0.5 -0.6 -0.6
Leg pain on walking 2.0 2.6 5.6 -1.9 -0.0 -1.8 -1.6 -1.9 -0.2 -1.9 -1.3 -1.0 1.7 1.0 -1.9 -2.0 -1.9 -2.4 -1.8 -0.8 -1.7 -1.8 -1.7 -1.6 -1.5 -1.2
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 2.3 -1.0 -0.0 -0.1 -0.0 -0.1 1.5 0.0 0.1 -0.0 0.1 -0.8 -0.1 -0.5 -0.4 -0.6 -0.3 -0.2 -0.2 -0.3 -0.3 -0.2 -0.2 0.0
Commuting to job workplace: Car/motor vehicle 0.5 0.6 1.6 0.6 0.2 0.9 0.6 0.4 -0.5 0.0 -0.0 0.9 -0.6 -1.3 1.1 1.1 0.9 0.4 0.9 0.1 0.8 0.8 1.0 0.7 0.8 0.7
Illness, injury, bereavement, stress in last 2 years 0.1 0.1 0.9 0.1 -0.3 0.0 0.5 0.8 -0.3 1.0 0.7 0.2 -0.3 -0.3 -0.0 -0.3 -0.2 0.1 0.1 0.5 0.1 0.2 0.0 0.2 0.3 0.3
Medication: Aspirin 1.0 1.3 6.2 -0.2 -2.0 -0.4 -1.0 -1.1 -2.5 -1.5 -1.9 -0.0 0.9 1.6 -0.6 0.3 -0.2 -1.5 -0.3 -1.6 -0.5 -0.6 -0.2 -0.7 -0.6 -0.5
Supplements: Vitamin C 0.1 0.1 1.6 -0.0 -0.2 -0.0 0.1 -0.1 -1.3 -0.3 -0.0 -0.3 0.2 -0.2 0.3 -0.3 -0.1 0.4 -0.1 0.2 -0.0 -0.0 -0.1 -0.0 0.0 0.0
Knee pain experienced in last month 2.4 3.7 6.9 -2.6 0.8 -2.0 -1.9 -2.5 -0.9 -1.9 -1.1 -1.5 2.5 0.6 -1.4 -2.2 -2.3 -2.2 -2.1 -1.7 -2.1 -2.1 -2.1 -2.0 -2.0 -1.8
Hypertension (Self-reported) 0.5 1.5 4.5 1.6 -0.2 1.5 0.4 0.3 -1.5 -0.1 0.0 1.2 -1.1 0.8 1.1 2.1 1.7 0.7 1.4 0.3 1.4 1.5 1.6 1.2 1.4 1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 1.8 -0.4 -0.7 -0.9 -0.5 -0.3 -0.0 -0.8 -1.3 -0.7 0.4 -0.1 0.2 -0.6 -0.6 -0.4 -0.7 -1.3 -0.7 -0.7 -0.7 -0.8 -0.8 -0.9
Illnesses of father: Heart disease 0.6 0.9 4.8 1.3 -0.5 0.8 0.3 0.7 -0.1 -0.2 0.1 -0.7 -1.1 0.2 0.7 0.7 1.2 2.2 0.9 1.1 1.1 1.2 0.8 0.9 0.9 0.9
Illnesses of siblings: Diabetes 0.1 0.1 1.6 0.0 -0.6 0.1 -0.1 -0.1 -1.2 -0.1 -0.3 0.2 -0.2 0.0 0.5 0.5 0.3 -0.4 0.1 -0.6 -0.0 -0.1 0.2 -0.1 0.0 -0.1
Smoking status: Previous 3.1 4.6 10.1 1.6 1.6 1.9 2.9 2.5 0.8 2.3 2.1 2.3 -2.3 -3.1 3.2 2.7 2.3 1.9 2.2 0.8 1.9 1.9 2.2 1.8 1.7 1.3
Forced expiratory volume in 1-second (FEV1), predicted 1.6 3.4 10.9 -1.5 -1.3 -1.8 -2.0 -1.8 0.5 -1.7 -1.2 -1.1 1.7 2.0 -3.1 -3.3 -2.5 -2.4 -2.0 0.4 -1.6 -1.8 -2.0 -1.2 -1.4 -0.7
Whole body fat-free mass 0.1 0.8 3.5 -1.0 -1.2 0.1 0.3 0.0 1.8 -1.2 -0.7 1.1 0.6 -0.5 -1.1 -1.4 -0.3 -1.0 -0.3 1.9 0.2 -0.1 -0.2 0.4 0.5 1.1
Leg fat-free mass (right) 0.2 0.9 4.4 -0.6 -1.1 0.6 0.9 0.6 2.1 -0.5 -0.4 1.6 0.0 -1.1 -0.4 -0.7 0.3 -0.6 0.2 1.8 0.6 0.4 0.4 0.8 0.9 1.3
Arm fat percentage (left) 0.4 1.7 5.3 -0.1 0.5 1.5 1.9 1.4 1.5 1.0 1.0 1.8 -1.0 -2.3 1.0 0.9 1.2 0.6 1.4 1.2 1.4 1.1 1.5 1.4 1.4 1.3
Average weekly red wine intake 0.3 0.5 3.8 0.7 -1.9 -0.1 -0.2 -0.1 -0.2 -1.1 -1.7 -0.2 0.2 0.9 -0.7 -0.5 -0.1 -0.0 -0.0 0.2 0.1 -0.0 -0.0 0.0 0.2 0.2
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.4 0.1 -0.3 0.2 0.1 0.3 0.3 -0.1 0.3 -0.3 -0.3 0.5 0.0 -0.1 0.2 0.6 0.2 0.7 0.3 0.4 0.1 0.3 0.3 0.4
Mood swings 0.2 0.4 2.4 -1.6 0.5 -0.3 0.3 -0.2 1.2 0.3 1.1 0.5 0.4 0.2 -0.9 -0.3 -0.4 -0.6 -0.5 -0.3 -0.6 -0.7 -0.4 -0.5 -0.5 -0.7
Loneliness, isolation 0.1 0.2 1.1 -0.3 -0.2 0.2 0.7 0.1 0.0 -0.6 -0.3 1.1 -0.2 -0.2 0.5 0.7 0.4 -0.3 0.2 -0.7 0.0 -0.1 0.3 -0.1 -0.0 -0.3
Long-standing illness, disability or infirmity 0.3 0.5 2.1 -1.2 0.6 -0.6 -0.3 -0.9 -0.4 -0.6 -0.1 0.4 0.6 0.4 -0.0 -0.1 -0.5 -1.5 -0.6 -1.1 -0.7 -0.7 -0.5 -0.7 -0.7 -0.5
Ever had bowel cancer screening 0.6 0.6 3.9 -0.0 1.5 0.4 0.3 -0.0 0.0 1.7 2.0 0.7 0.0 -0.4 0.8 1.6 0.5 -0.3 0.4 -1.0 0.0 0.2 0.4 0.0 -0.1 -0.2
Diabetes diagnosed by doctor 3.4 5.6 8.8 -2.6 -1.7 -2.4 -2.7 -2.9 -2.1 -3.0 -2.4 -2.6 2.7 2.6 -2.3 -2.2 -2.1 -2.1 -2.4 -2.1 -2.2 -2.3 -2.3 -2.4 -2.1 -2.0
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 0.4 0.2 -0.1 0.5 0.5 0.5 0.4 -0.1 -0.3 0.2 -0.2 -0.6 0.5 0.5 0.6 0.6 0.5 0.6 0.5 0.4 0.6 0.4 0.5 0.3
Friendships satisfaction 1.0 1.2 2.6 -1.3 0.8 -1.0 -1.5 -1.6 0.6 -0.7 -0.2 -1.5 1.2 1.5 -1.0 -0.5 -1.0 -0.9 -1.0 -1.0 -1.1 -1.1 -1.0 -1.2 -1.2 -1.2
Qualifications: nursing, teaching 1.2 1.9 6.2 1.1 2.5 1.4 0.6 0.7 1.3 1.9 2.1 0.7 -1.0 0.2 0.9 2.1 1.3 1.1 1.5 0.8 1.2 1.5 1.5 1.3 1.1 1.1
Commuting to job workplace: Walk 0.2 0.3 2.7 -0.3 0.3 -0.2 0.1 0.1 0.4 1.1 1.6 -0.5 -0.2 0.6 -0.3 -0.2 -0.2 0.5 -0.3 0.2 -0.2 -0.0 -0.4 -0.1 -0.3 -0.2
Eye problems/disorders: Cataract 1.5 1.7 4.0 1.6 0.2 1.3 1.1 1.3 -0.1 1.3 0.7 0.8 -1.5 -0.9 2.0 2.0 1.8 1.6 1.2 0.2 1.4 1.5 1.2 1.2 1.2 1.3
Mouth/teeth dental problems: Mouth ulcers 3.0 4.8 8.7 1.9 1.2 2.3 2.2 2.1 1.5 1.9 1.2 1.7 -2.5 -2.6 3.0 2.9 2.8 2.4 2.4 1.2 2.3 2.4 2.4 2.1 2.3 2.0
Medication for cholesterol 0.2 0.3 1.7 0.5 0.4 0.2 0.6 0.9 1.0 0.2 -0.2 0.0 -0.5 -1.3 0.6 -0.2 0.2 0.8 0.2 0.8 0.3 0.2 0.1 0.3 0.2 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 1.5 0.3 0.0 0.9 1.0 0.6 -1.0 0.6 0.6 1.0 -0.3 -1.2 1.1 1.0 0.9 0.7 1.0 0.4 0.9 0.8 1.0 0.8 0.8 0.7
Back pain experienced in last month 1.2 1.8 5.2 -2.3 -0.2 -1.7 -0.2 -0.7 -0.0 -0.0 0.1 -0.2 0.9 -0.2 -0.8 -1.3 -1.6 -1.6 -1.6 -1.9 -1.7 -1.8 -1.6 -1.7 -1.7 -1.9
Mineral and other dietary supplements 2.2 3.0 4.5 -1.9 -1.0 -1.7 -1.8 -2.1 -1.0 -2.0 -1.7 -1.8 1.9 1.4 -2.1 -1.8 -1.7 -1.9 -1.7 -1.6 -1.7 -1.9 -1.6 -1.7 -1.7 -1.6
Breast cancer (self-reported) 0.5 0.6 2.3 0.8 -0.1 0.8 1.5 1.2 0.3 0.6 0.6 1.1 -1.3 -0.9 0.9 0.8 0.8 0.7 0.7 0.3 0.7 0.6 0.7 0.7 0.6 0.5
Asthma (self-reported) 0.9 1.8 5.5 1.1 0.8 1.5 1.4 0.9 1.4 0.0 -0.2 0.8 -1.1 -2.3 1.9 1.0 1.5 1.4 1.4 1.3 1.6 1.4 1.4 1.5 1.6 1.6
Osteoporosis (self-reported) 0.9 1.1 4.0 1.3 1.3 1.2 0.9 0.7 0.1 1.2 1.2 0.9 -1.1 -0.4 1.3 2.0 1.2 0.7 1.2 -0.2 0.9 0.9 1.2 0.8 0.7 0.4
Osteoarthritis (self-reported) 0.3 0.3 2.0 -0.7 0.8 -0.3 -0.5 -0.6 1.0 0.1 -0.2 0.4 0.7 0.2 -0.2 -0.1 -0.5 -1.4 -0.4 -0.9 -0.5 -0.4 -0.3 -0.4 -0.4 -0.1
Medication: Aspirin 0.7 1.0 5.1 -0.0 -2.0 -0.2 -0.9 -1.0 -2.3 -1.5 -1.8 -0.2 0.8 1.4 -0.5 0.3 0.1 -0.9 -0.1 -1.1 -0.2 -0.3 -0.0 -0.5 -0.3 -0.3
Medication: Gliclazide 0.5 0.6 1.7 -0.7 -0.2 -0.6 -1.1 -1.2 -0.2 -1.0 -0.9 -0.8 1.2 1.3 -0.9 -0.6 -0.5 -0.5 -0.6 -0.7 -0.6 -0.6 -0.6 -0.6 -0.6 -0.5
Illnesses of father: None of the above (group 1) 0.4 0.5 1.2 -1.1 0.8 -0.7 -0.3 -0.4 0.7 0.4 0.3 0.0 0.9 -0.3 -0.6 -1.0 -1.0 -1.0 -0.8 -0.3 -0.8 -0.8 -0.8 -0.6 -0.6 -0.5
Smoking status: Current 0.1 0.2 1.3 -0.6 0.0 -0.2 -0.1 -0.5 0.9 -1.1 -0.8 -0.5 0.1 -0.7 -0.1 -0.3 -0.1 0.0 -0.1 -0.0 -0.2 -0.4 -0.1 -0.3 -0.3 -0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.9 1.9 6.7 -1.1 -1.5 -1.4 -1.4 -0.8 0.6 -1.2 -1.0 -2.6 1.4 1.5 -1.5 -1.9 -1.3 0.2 -1.6 -0.4 -1.2 -1.2 -1.7 -1.3 -1.3 -1.3
Whole body water mass 0.1 0.9 2.9 -1.1 -1.3 0.0 0.2 -0.0 1.6 -1.3 -0.8 1.2 0.7 -0.4 -1.1 -1.5 -0.4 -1.3 -0.4 1.7 0.1 -0.2 -0.3 0.3 0.4 1.0
Leg predicted mass (right) 0.2 0.8 4.2 -0.6 -1.1 0.5 0.9 0.6 2.0 -0.5 -0.4 1.6 0.1 -1.1 -0.4 -0.8 0.2 -0.6 0.2 1.8 0.6 0.3 0.3 0.7 0.8 1.3
Arm fat mass (left) 0.2 0.8 3.3 -0.8 0.0 0.9 1.3 0.7 1.4 0.1 0.4 1.6 -0.3 -1.8 0.3 0.0 0.5 -0.4 0.7 1.2 0.8 0.5 0.8 0.9 0.9 1.1
Number of self-reported non-cancer illnesses 0.5 0.9 4.0 1.0 0.9 1.1 0.5 0.4 0.1 0.5 0.5 1.1 -1.0 -0.1 1.3 2.0 1.4 0.3 1.1 -0.1 0.9 1.0 1.2 0.8 0.8 0.8
Average weekly champagne plus white wine intake 0.2 0.3 1.0 0.6 -0.5 0.3 0.6 1.0 -0.0 0.3 0.0 0.2 -0.9 -0.5 0.9 0.3 0.5 1.0 0.4 0.6 0.6 0.6 0.4 0.5 0.5 0.5
Miserableness 0.4 0.6 2.5 -0.2 0.9 0.5 1.2 0.8 0.6 1.1 1.6 0.7 -0.9 -1.2 0.7 1.1 0.9 0.6 0.6 0.1 0.5 0.4 0.7 0.4 0.5 0.1
Guilty feelings 0.9 1.3 3.2 0.7 1.5 1.2 1.3 0.8 1.5 0.4 0.6 1.1 -1.1 -1.8 1.4 0.9 1.1 0.9 1.1 1.2 1.2 1.1 1.2 1.2 1.2 1.1
Wears glasses or contact lenses 1.0 1.1 2.1 1.4 -0.2 1.1 1.0 1.1 0.3 0.2 -0.8 0.7 -1.3 -0.8 1.4 1.1 1.4 1.2 1.2 0.7 1.2 1.1 1.2 1.1 1.2 1.0
Ever taken oral contraceptive pill 0.2 0.2 2.2 0.7 -0.5 0.2 -0.3 -0.4 -1.5 -0.4 -0.5 -0.8 0.2 0.4 0.3 0.2 0.3 0.8 0.2 -0.3 0.1 0.1 0.1 0.0 0.1 -0.2
Hearing aid user 0.6 0.7 1.6 -1.3 1.1 -0.8 -1.2 -1.2 1.0 -0.2 0.2 -1.1 0.8 0.5 -0.3 -0.6 -0.7 -0.7 -0.8 -0.7 -0.8 -0.7 -0.8 -0.7 -0.7 -0.7
Mother’s age at death 0.6 0.7 2.1 -0.4 -0.7 -0.7 -1.0 -0.7 -0.7 -0.9 -1.4 -0.7 0.9 0.8 -0.3 -0.5 -0.8 -0.7 -1.0 -1.3 -0.9 -0.9 -1.0 -1.0 -1.0 -0.8
Financial situation satisfaction 5.2 6.5 11.5 -2.9 -2.1 -2.6 -2.7 -2.8 -1.1 -3.1 -2.4 -2.7 2.7 2.8 -3.4 -3.2 -2.6 -2.3 -2.6 -1.2 -2.4 -2.5 -2.6 -2.4 -2.3 -2.0
Tinnitus: Yes, now most or all of the time 0.9 1.0 2.5 -1.1 0.8 -0.9 -1.3 -1.2 0.3 -0.2 -0.0 -1.6 1.3 1.0 -1.2 -1.0 -1.1 -0.6 -1.1 -0.9 -1.1 -1.1 -1.1 -1.0 -1.0 -1.2
Commuting to job workplace: Public transport 0.5 0.6 1.6 1.1 0.2 0.6 0.9 1.1 0.7 0.8 0.7 1.0 -0.9 0.2 0.2 0.6 0.7 0.6 0.6 1.3 0.7 0.8 0.6 0.8 0.6 0.8
Eye problems/disorders: Glaucoma 0.2 0.2 1.0 -0.6 -0.6 -0.5 -0.3 -0.2 -0.4 -0.6 -0.5 -0.4 -0.0 0.9 -0.2 0.1 -0.1 -0.2 -0.3 -1.0 -0.4 -0.3 -0.3 -0.6 -0.5 -0.6
Medication: Blood pressure 0.8 1.4 3.6 1.1 -0.1 1.5 0.9 0.5 -0.6 -0.2 0.3 1.1 -1.2 -0.1 1.6 1.9 1.7 1.1 1.6 0.5 1.5 1.5 1.6 1.3 1.5 1.3
Pain type(s) experienced in last month: Hip pain 1.1 1.4 3.6 -1.6 0.9 -1.1 -1.4 -1.6 0.0 -0.8 -0.6 -0.8 1.4 0.6 -0.8 -0.5 -1.2 -1.9 -1.1 -1.6 -1.4 -1.3 -1.0 -1.3 -1.3 -1.3
Supplements: Fish oil (including cod liver oil) 1.8 2.4 5.2 1.5 0.8 1.3 1.9 2.3 1.2 2.2 1.7 1.9 -1.7 -1.4 1.8 1.1 1.2 1.4 1.2 1.6 1.4 1.5 1.2 1.4 1.5 1.5
High cholesterol (Self-reported) 0.6 1.1 2.2 -1.4 -1.2 -1.0 -1.1 -1.0 -0.8 -0.7 -0.7 -0.4 1.2 1.3 -1.4 -0.7 -0.9 -1.5 -1.0 -1.0 -1.0 -1.0 -0.9 -1.0 -1.0 -0.9
Medication: Bendroflumethiazide 1.4 2.1 6.2 1.5 0.2 1.7 1.3 1.0 -1.1 0.8 0.6 2.3 -1.3 -0.7 1.9 2.5 1.8 0.5 1.9 0.1 1.5 1.5 2.0 1.4 1.5 1.3
Medication: Paracetamol 0.3 0.4 2.1 0.4 -1.2 0.2 0.8 0.8 0.1 0.4 -0.9 1.5 -0.5 -1.4 0.6 0.3 0.3 -0.8 0.3 -0.4 0.2 0.1 0.4 0.2 0.4 0.3
Medication: Lisinopril 0.5 0.7 3.0 -0.5 -0.6 -0.8 -0.5 -0.6 -1.6 -0.5 -0.2 -0.2 0.4 1.6 -0.4 0.3 -0.4 -0.8 -0.6 -1.7 -0.9 -0.7 -0.6 -1.0 -0.8 -1.1
Medication: Atorvastatin 0.2 0.2 1.9 -0.2 -1.2 0.2 -0.2 -0.4 -1.4 -0.3 -0.1 0.2 0.2 0.7 -0.1 0.7 0.3 -0.5 0.2 -0.6 0.1 0.1 0.3 -0.0 0.0 0.2
Illnesses of father: High blood pressure 0.3 0.3 2.0 0.1 -0.1 -0.3 -0.8 -0.6 -0.3 -1.4 -0.9 -0.8 0.3 1.2 -0.5 -0.7 -0.2 0.2 -0.4 0.6 -0.2 -0.2 -0.4 -0.2 -0.2 -0.1
Alcohol drinker status: Never 1.6 1.9 4.0 -2.0 -0.4 -1.4 -1.1 -1.2 -0.4 0.1 0.3 -1.1 1.5 1.4 -1.9 -1.5 -1.7 -1.7 -1.5 -1.6 -1.5 -1.5 -1.5 -1.4 -1.4 -1.3
Ever smoked 4.2 7.4 17.9 2.1 1.3 2.6 3.8 3.2 1.6 2.2 1.9 2.8 -3.2 -4.2 3.9 3.2 3.0 2.5 2.8 1.4 2.5 2.5 2.9 2.4 2.4 1.9
Basal metabolic rate 0.2 0.9 3.3 -1.1 -1.2 0.2 0.4 0.0 1.8 -1.2 -0.7 1.3 0.6 -0.6 -1.1 -1.4 -0.3 -1.2 -0.3 1.8 0.2 -0.1 -0.1 0.4 0.5 1.1
Leg fat percentage (left) 0.3 0.9 3.8 -0.4 0.3 1.1 1.3 0.7 1.1 -0.2 -0.0 1.5 -0.7 -1.9 0.8 0.3 0.8 -0.0 1.0 1.1 1.0 0.7 1.1 1.1 1.1 1.2
Arm fat-free mass (left) 0.2 1.2 3.8 -1.6 -1.4 -0.4 -0.3 -0.6 1.2 -1.9 -1.2 1.0 1.0 -0.1 -1.5 -1.8 -0.8 -2.0 -0.8 1.2 -0.3 -0.6 -0.6 -0.2 -0.1 0.7
Number of operations (self-reported) 0.3 0.5 2.2 -0.4 0.8 0.0 0.5 -0.0 -0.4 0.3 0.2 1.3 -0.3 -0.9 1.4 1.1 0.2 -0.9 0.0 -1.5 -0.2 -0.1 0.1 -0.3 -0.3 -0.3
Average weekly beer plus cider intake 0.3 0.4 4.8 -0.6 2.2 -0.0 0.0 -0.5 0.1 0.3 1.3 0.2 -0.2 -0.3 -0.0 0.4 -0.1 -0.3 -0.0 -0.5 -0.3 -0.4 -0.0 -0.2 -0.4 -0.7
Irritability 0.1 0.2 1.2 -0.2 -0.8 0.2 -0.1 -0.6 -0.9 -1.1 -0.3 0.2 -0.1 1.0 -0.3 0.7 0.4 0.2 0.2 -0.6 0.0 -0.0 0.2 -0.2 -0.2 -0.3
Risk taking 0.8 1.2 2.9 -1.3 0.0 -1.1 -1.3 -1.7 -0.1 -1.4 -1.0 -0.8 1.4 0.5 -1.0 -0.9 -1.0 -1.6 -1.1 -1.3 -1.1 -1.2 -1.0 -1.1 -1.0 -1.0
Ever had prostate specific antigen (PSA) test 0.3 0.3 0.8 0.3 0.4 0.5 0.2 0.5 0.6 0.8 0.4 -0.4 -0.1 -0.7 0.5 0.5 0.6 0.9 0.5 0.5 0.6 0.6 0.5 0.5 0.5 0.5
Fractured/broken bones in last 5 years 0.4 0.5 1.7 0.8 -0.0 0.7 0.8 0.5 0.2 -0.0 -0.5 1.3 -0.6 -0.8 1.0 0.9 0.7 -0.2 0.7 -0.1 0.7 0.6 0.8 0.6 0.7 0.8
Age started oral contraceptive pill 0.2 0.3 2.6 0.2 0.3 0.3 0.3 0.5 0.6 1.6 1.3 0.5 -0.3 -0.2 0.1 0.1 0.1 -0.1 0.1 0.4 0.2 0.4 0.1 0.4 0.5 0.6
Diastolic blood pressure, automated reading 0.8 2.5 9.8 -0.5 -1.8 -1.0 -1.4 -1.5 -2.2 -3.1 -2.5 -0.6 1.4 3.1 -2.1 -1.5 -1.1 -1.4 -1.1 -0.2 -0.9 -1.1 -1.0 -1.0 -1.0 -0.7
Ever depressed for a whole week 4.5 5.6 10.7 1.6 3.3 2.5 2.4 1.7 1.2 2.1 2.8 2.0 -2.2 -2.7 3.0 3.1 2.6 2.1 2.5 1.5 2.3 2.3 2.6 2.3 2.2 1.9
Unable to work because of sickness or disability 0.3 0.4 2.4 -0.9 1.5 -0.0 0.5 -0.1 0.3 0.6 1.0 0.7 0.0 -0.8 0.6 0.8 0.1 -0.5 0.1 -0.8 -0.2 -0.2 0.2 -0.2 -0.3 -0.5
Commuting to job workplace: Cycle 1.0 1.2 2.4 -0.8 -1.6 -1.2 -0.9 -0.7 -0.9 -1.2 -1.3 -1.2 0.7 1.3 -0.8 -0.8 -0.8 -0.5 -1.1 -1.1 -1.2 -1.2 -1.1 -1.3 -1.2 -1.4
Myopia 4.1 5.9 8.4 2.6 2.2 2.3 2.8 2.9 2.6 1.9 1.5 2.5 -2.9 -2.4 2.6 2.1 2.4 2.5 2.6 2.6 2.4 2.3 2.5 2.5 2.4 2.0
Vascular/heart problems diagnosed by doctor 0.5 1.2 3.6 -1.2 0.3 -1.4 -0.3 -0.2 1.4 -0.0 -0.0 -1.5 0.9 -0.6 -0.9 -1.9 -1.5 -0.2 -1.3 -0.3 -1.3 -1.3 -1.5 -1.1 -1.3 -1.4
Cholesterol lowering medication 2.3 3.4 7.5 -2.0 -1.9 -1.8 -1.7 -2.0 -2.7 -1.2 -0.5 -1.8 1.7 2.5 -2.1 -1.2 -1.6 -1.5 -1.7 -2.3 -1.8 -1.8 -1.7 -1.9 -1.8 -1.9
Medication: Omeprazole (e.g. Zanprol) 0.2 0.3 1.4 0.1 0.0 0.3 0.7 0.3 0.7 0.2 -0.1 0.9 -0.2 -1.2 0.8 0.7 0.6 -0.0 0.6 -0.2 0.4 0.3 0.6 0.4 0.4 0.3
Pain experienced in last month 1.3 2.2 5.1 2.3 -1.2 1.6 1.1 1.8 0.8 0.8 -0.1 1.0 -1.3 -0.3 0.6 1.0 1.6 1.7 1.6 2.1 1.8 1.8 1.5 1.8 1.7 2.0
Supplements: Calcium 2.7 3.0 5.8 1.5 2.4 1.9 1.5 1.3 1.6 1.3 1.5 1.2 -1.7 -2.0 2.1 2.0 1.9 1.7 1.8 1.5 1.7 1.8 1.8 1.7 1.7 1.6
Basal cell carcinoma (self-reported) 0.8 0.9 3.5 0.8 -0.7 0.8 0.9 1.2 1.9 1.3 0.6 1.1 -0.7 -0.8 0.2 0.3 0.7 0.6 0.7 1.4 0.9 1.0 0.7 1.0 1.1 1.2
Heart attack/myocardial infarction (self-reported) 2.3 2.9 5.4 -1.6 -2.3 -1.7 -1.8 -1.7 -1.8 -1.7 -2.1 -1.1 1.7 1.7 -1.6 -1.5 -1.5 -2.1 -1.5 -2.1 -1.6 -1.6 -1.5 -1.7 -1.5 -1.4
Deep venous thrombosis (DVT) (self-reported) 0.1 0.1 0.7 0.1 0.8 0.0 -0.4 -0.2 0.9 0.6 -0.1 -0.4 0.3 -0.6 0.6 0.4 0.1 -0.1 0.0 -0.5 -0.0 -0.0 0.1 -0.0 0.0 -0.1
Heart disease (siblings) 2.0 2.4 6.4 1.6 1.7 1.7 1.1 1.1 0.2 1.4 1.0 1.3 -1.3 -1.4 2.3 2.5 1.9 1.2 1.9 0.5 1.6 1.7 1.9 1.6 1.6 1.3
Alcohol drinker status: Previous 1.3 1.4 4.2 1.3 -1.5 1.0 1.6 1.6 -1.1 -0.2 -0.2 0.5 -1.3 -1.1 1.2 0.4 1.3 2.0 1.0 1.5 1.2 1.2 0.9 1.1 1.2 1.1
Pack years of smoking 1.2 1.8 4.5 -1.0 -2.1 -1.4 -1.1 -1.3 -1.5 -1.3 -1.4 -0.6 1.2 1.7 -1.7 -1.2 -1.1 -1.6 -1.2 -1.2 -1.3 -1.4 -1.2 -1.3 -1.2 -1.2
Impedance of whole body 1.4 7.3 15.1 -1.7 -1.8 -3.0 -2.9 -2.4 -2.2 -1.5 -1.6 -1.9 2.3 3.5 -3.9 -3.4 -3.6 -3.3 -2.9 -1.8 -2.9 -2.9 -3.0 -2.7 -2.8 -2.5
Leg fat mass (left) 0.2 0.6 2.4 -1.1 -0.3 0.6 0.8 0.3 1.3 -0.7 -0.5 1.4 0.0 -1.6 0.0 -0.4 0.2 -0.8 0.4 1.1 0.6 0.2 0.5 0.6 0.7 1.0
Arm predicted mass (left) 0.2 1.2 4.0 -1.7 -1.4 -0.4 -0.2 -0.6 1.3 -1.9 -1.1 0.9 1.0 -0.2 -1.5 -2.0 -0.8 -1.9 -0.9 1.3 -0.4 -0.7 -0.7 -0.2 -0.1 0.6