TWAS hub - SCGB3A1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.1463	0.033	2.9e-07	0.112	0.073	0.106	0.112	0.111	2.1e-16	5.1e-11	1.4e-15	2.3e-16	2.8e-16
2	NTR	Blood	0.0878	0.017	8.2e-14	0.066	0.054	0.062	0.061	0.064	1.8e-20	7.5e-17	2.7e-19	6.8e-19	7.0e-20
3	ROSMAP	Brain Pre-frontal Cortex	0.3159	0.041	0.0e+00	0.234	0.178	0.242	0.240	0.254	9.7e-30	2.5e-22	8.3e-31	1.8e-30	2.1e-32

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Number of children fathered	4.9	5.5	8.9	2.7	3.0	-0.6
Prospective memory result	4.2	5.1	7.9	-2.8	-2.7	0.6
Worry too long after embarrassment	3.5	5.8	6.9	2.2	2.3	-2.6
Hair/balding pattern: Pattern 2	3.3	4.2	5.2	2.0	1.9	2.3
Age at last live birth	3.3	4.7	5.8	2.4	2.4	1.7
Illnesses of siblings	3.1	4.4	6.1	-2.4	-2.5	1.0
Prostate Cancer	3.0	4.2	6.8	-2.6	-2.4	0.2
Coronary Artery Disease (CAD)	2.8	3.4	4.8	-2.2	-2.0	-1.1
Mouth/teeth dental problems	2.8	4.3	9.4	1.2	1.4	3.1
Ever had hysterectomy (womb removed)	2.7	3.1	6.1	1.2	1.3	-2.5
Father’s age at death	2.7	3.6	4.6	-1.9	-2.1	-1.6
Ever used hormone-replacement therapy (HRT)	2.5	3.2	4.6	2.1	2.0	-1.1
Birth weight of first child	2.5	4.5	6.1	2.5	2.4	-1.3
Pulse wave peak to peak time	2.5	3.0	4.1	2.0	2.0	0.9
Age at first live birth	2.4	4.3	5.0	2.1	2.2	1.9
Frequency of depressed mood in last 2 weeks	2.3	3.3	5.2	1.6	1.5	-2.3
Pain all over the body in last month	2.3	2.4	5.1	-1.2	-0.9	2.3
Illness, injury, bereavement, stress in last 2 years	2.3	2.8	4.3	-2.0	-2.1	-0.2
Tinnitus: Yes, now most or all of the time	2.3	2.6	2.8	1.6	1.6	-1.7
Pack years adult smoking proportion	2.2	3.4	5.3	-2.3	-2.2	0.1
Medication: Levothyroxine sodium	2.2	3.7	5.4	-2.3	-2.3	0.5
Worrier / anxious feelings	2.2	4.1	4.7	1.9	2.2	-2.0
Medication: Lisinopril	2.2	2.9	4.8	2.0	2.2	-0.2
Pack years of smoking	2.2	3.2	4.9	-2.2	-2.1	0.4
Lung cancer (father)	2.1	2.5	3.6	1.7	1.9	1.0
Pulse wave Arterial Stiffness index	2.1	2.4	3.2	-1.8	-1.8	-1.0
Emphysema/chronic bronchitis	2.1	2.4	3.8	-1.9	-1.8	-0.4
Breast cancer (self-reported)	2.1	2.5	4.0	-2.0	-1.8	0.6
Breastfed as a baby	2.0	2.5	4.3	-1.3	-1.3	-2.1
Leg pain on walking	2.0	2.5	3.7	-1.8	-1.9	-0.6
Hearing aid user	2.0	2.2	5.1	-1.0	-0.8	-2.2
Comparative body size at age 10	1.9	5.3	8.2	-2.9	-2.8	0.3
Family relationship satisfaction	1.9	2.3	3.5	-1.9	-1.8	0.3
Heart disease (siblings)	1.9	2.3	2.9	1.5	1.3	-1.7
HbA1C	1.8	2.0	2.8	-1.6	-1.7	-0.9
Wears glasses or contact lenses	1.8	2.1	3.2	1.8	1.8	0.1
High cholesterol (Self-reported)	1.8	3.2	4.7	1.9	2.2	-1.1
Neuroticism	1.7	4.2	7.5	1.6	1.6	-2.7
Serious illness, injury or assault of a close relative in last 2 years	1.7	1.9	3.0	1.7	1.6	0.4
Loud music exposure frequency	1.7	1.9	3.0	-1.7	-1.5	0.8
Schizophrenia vs Biploar Disorder	1.6	2.1	6.2	-0.4	-0.3	2.5
Neuroticism score	1.6	3.4	7.7	1.1	1.1	-2.8
Chest pain or discomfort	1.6	2.3	6.1	-0.8	-0.5	2.5
Alzheimer’s Disease (in father)	1.5	1.6	1.9	-1.4	-1.3	-1.0
Blood Platelet Count	1.5	17.4	26.9	-5.2	-4.9	-1.0
Diabetes (self-reported)	1.5	2.3	3.6	1.8	1.9	-0.2
Number of full brothers	1.5	1.9	2.9	1.6	1.7	-0.5
Medication: Omeprazole	1.5	1.8	2.6	1.3	1.1	1.6
Illnesses of siblings: Diabetes	1.5	1.9	2.8	1.7	1.7	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.2	4.1	1.6	1.7	-2.0
Average weekly beer plus cider intake	1.5	2.2	3.8	-1.7	-2.0	-0.2
Worry (Nagel 2018)	1.4	3.0	7.4	0.9	0.9	-2.7
Fasting Glucose	1.4	1.7	2.0	-1.3	-1.2	-1.4
Blood Eosinophil Count	1.4	10.4	16.2	-3.8	-4.0	0.7
Financial difficulties in last 2 years	1.4	1.8	2.8	1.6	1.7	-0.2
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	2.6	-1.6	-1.6	-0.5
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.6	1.8	1.2	1.2	-1.3
Diabetes diagnosed by doctor	1.4	2.3	3.1	1.7	1.8	-1.0
Osteoarthritis (self-reported)	1.4	1.8	3.9	-0.9	-0.9	2.0
Crohns Disease (2012)	1.3	2.1	2.6	1.1	1.5	-1.6
Type 2 Diabetes (T2D) (2012)	1.3	1.5	3.0	-0.9	-0.8	-1.7
Blood Red Count	1.3	12.6	18.5	3.7	4.3	2.4
Medication: Metformin	1.3	1.9	3.0	1.6	1.7	-0.2
Medication: Lansoprazole	1.3	1.5	2.4	1.5	1.4	-0.3
Pulse wave reflection index	1.3	1.7	2.4	-1.6	-1.5	-0.5
Hypothyroidism/myxoedema (self-reported)	1.3	2.6	3.7	-1.9	-1.8	1.0
Guilty feelings	1.3	2.0	2.4	1.5	1.4	-1.3
Medication: Paracetamol	1.3	2.0	2.8	-1.7	-1.5	0.9
Risk taking	1.3	1.9	3.0	-1.7	-1.7	-0.1
Neuroticism (Nagel 2018)	1.2	2.8	6.3	0.9	1.1	-2.5
Schizophrenia (2018)	1.2	2.6	4.2	-1.8	-2.1	0.5
Crohns Disease (2017)	1.2	2.5	4.9	1.1	1.2	-2.2
Major Depression (MDD)	1.2	1.5	2.1	-1.3	-1.4	-0.8
Diabetes (father)	1.2	1.5	2.1	1.4	1.4	0.5
Severe depression (siblings)	1.2	1.4	2.0	1.4	1.3	-0.6
Loneliness, isolation	1.2	1.6	4.0	-0.8	-0.5	-2.0
Long-standing illness, disability or infirmity	1.2	1.8	4.3	-0.9	-0.5	-2.1
LDL Cholesterol	1.1	1.7	2.2	1.3	1.2	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	3.9	-0.2	-0.5	-2.0
Mouth/teeth dental problems: Dentures	1.1	1.8	5.4	-0.2	-0.2	-2.3
Tense / ‘highly strung’	1.1	1.8	5.5	0.1	0.1	-2.3
Glaucoma (self-reported)	1.1	1.3	1.5	-1.2	-1.2	-1.0
Friendships satisfaction	1.1	1.4	2.1	-1.4	-1.4	-0.4
Commuting to job workplace: Walk	1.1	1.2	3.4	-0.3	-0.4	-1.8
Medication: Bendroflumethiazide	1.1	1.6	2.7	1.2	1.6	-0.8
HDL Cholesterol	1.0	1.6	2.4	1.6	1.5	-0.3
Multivitamins +/- minerals	1.0	1.2	1.3	1.1	1.1	1.1
Ever unenthusiastic/disinterested for a whole week	1.0	1.2	3.6	-0.2	-0.2	1.9
Medication: Paracetamol	1.0	1.6	2.1	-1.3	-1.1	1.4
Osteoporosis (self-reported)	1.0	1.2	3.6	-0.2	-0.1	1.9
Myopia	1.0	1.4	1.5	-1.2	-1.2	1.2
Intelligence (Savage-Jansen 2018)	0.9	2.9	4.3	2.1	2.0	-0.6
Hypothyroidism (self reported)	0.9	2.1	2.9	-1.7	-1.6	1.0
Hand grip strength (left)	0.9	2.4	3.5	1.7	1.9	-0.8
Average weekly spirits intake	0.9	1.1	1.4	0.9	1.1	1.2
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	2.6	-0.7	-0.5	-1.6
Fed-up feelings	0.9	1.6	1.9	1.1	1.3	-1.4
Hearing difficulty/problems with background noise	0.9	1.5	3.3	0.5	0.9	-1.8
Had menopause	0.9	1.1	2.2	1.5	1.1	0.2
Happiness	0.9	1.1	1.2	-1.1	-1.1	-0.9
Birth weight	0.9	1.8	2.7	-1.6	-1.4	-0.9
Exposure to tobacco smoke outside home	0.9	1.2	1.5	-1.2	-1.0	-1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	1.3	1.1	1.1	-1.0
Handedness (chirality/laterality): Left-handed	0.9	1.1	1.3	1.0	1.1	-1.1
Financial situation satisfaction	0.9	1.1	1.8	-1.3	-1.0	0.7
Age started oral contraceptive pill	0.9	1.1	1.6	1.3	1.1	-0.6
Bipolar Disorder or Schizophrenia	0.8	1.9	3.1	-1.6	-1.8	0.1
Alzheimer’s Disease (in mother)	0.8	1.0	2.2	0.7	0.5	1.5
Primary Biliary Cirrhosis	0.8	1.1	2.0	1.1	1.4	-0.2
Lung FVC	0.8	4.1	6.7	1.7	1.6	-2.6
Supplements: Zinc	0.8	0.9	0.9	0.9	0.9	1.0
Age when periods started (menarche)	0.8	2.0	2.3	1.5	1.4	1.3
Medication: Cholesterol lowering	0.8	1.2	1.7	1.2	1.3	-0.8
Chronic bronchitis/emphysema (mother)	0.8	1.0	1.2	-1.1	-1.1	-0.8
High blood pressure (siblings)	0.8	1.2	2.0	1.2	1.4	-0.6
Suffer from ‘nerves’	0.8	1.2	2.0	0.9	0.9	-1.4
Overall health rating	0.8	1.8	2.1	1.1	1.4	-1.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	1.8	-0.6	-0.8	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	2.1	1.3	1.5	-1.1
Ever had bowel cancer screening	0.8	1.0	2.1	-0.7	-0.6	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	1.6	-1.0	-1.3	-0.6
Medication: Aspirin	0.8	1.1	1.5	-0.9	-0.9	1.2
Number of operations (self-reported)	0.8	1.2	2.0	1.3	1.4	0.2
Ever depressed for a whole week	0.8	1.0	2.7	0.4	0.4	1.6
Unable to work because of sickness or disability	0.8	1.0	1.6	1.3	1.2	-0.0
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	1.7	1.3	1.1	0.4
Mean Putamen Volume	0.7	0.8	1.2	-0.8	-0.6	1.1
Medication for hormone replacement therapy	0.7	0.8	2.3	-0.2	-0.2	-1.5
Chronic bronchitis/emphysema (father)	0.7	0.9	2.4	0.4	0.1	-1.6
Nervous feelings	0.7	1.3	3.7	-0.3	-0.2	-1.9
Had other major operations	0.7	0.8	0.9	0.9	0.8	0.9
Depression (self-reported)	0.7	0.8	0.9	-1.0	-0.9	-0.9
Angina (self-reported)	0.7	0.9	1.4	-1.2	-0.8	0.9
Medication: Seretide 50 evohaler	0.7	0.9	2.0	-0.4	-0.7	-1.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	2.6	-0.6	-0.7	-1.6
Average weekly champagne plus white wine intake	0.7	1.0	2.9	-0.1	-0.2	-1.7
Ever taken oral contraceptive pill	0.7	0.8	2.1	0.4	0.4	1.4
Eye problems/disorders: Glaucoma	0.7	0.8	1.2	-1.1	-1.0	-0.3
Alcohol drinker status: Never	0.7	0.9	2.6	0.3	-0.2	1.6
Cholesterol lowering medication	0.7	1.0	1.4	1.0	1.2	-0.7
Irritable Bowel Disease (IBD)	0.6	1.4	1.5	1.1	1.2	-1.2
Rheumatoid Arthritis	0.6	0.8	1.3	1.1	0.8	-0.6
Schizophrenia (2014)	0.6	1.4	2.2	-1.1	-1.5	0.8
Angina	0.6	0.7	1.0	-1.0	-0.6	0.9
Relative age voice broke	0.6	0.9	2.5	-0.2	-0.2	1.6
Forced vital capacity (FVC)	0.6	2.3	3.7	1.7	1.9	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	3.3	1.4	1.8	-0.7
Hair/balding pattern: Pattern 4	0.6	1.5	4.3	0.3	0.4	-2.1
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.1	0.7	0.6	-1.1
Gout (self-reported)	0.6	0.9	1.6	0.8	0.6	-1.3
Forced vital capacity (FVC), Best measure	0.6	2.1	2.9	1.5	1.7	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.0	-0.2	-0.1	1.4
Commuting to job workplace: Public transport	0.6	0.7	1.0	1.0	1.0	-0.1
Verbal and Numeric Reasoning (VNR)	0.5	1.2	1.4	1.1	1.0	-1.2
Neuroticism (2016)	0.5	0.8	1.4	-0.6	-0.7	-1.2
Blood White Count	0.5	3.8	6.7	-2.6	-2.1	-0.1
Systolic Blood Pressure	0.5	2.7	4.8	-1.3	-1.3	-2.2
Sensitivity / hurt feelings	0.5	0.8	1.1	0.8	0.9	-1.0
Hand grip strength (right)	0.5	1.3	2.5	1.2	1.6	-0.1
Serious illness, injury or assault to yourself	0.5	0.6	1.1	-0.6	-0.7	1.1
Qualifications: None of the above	0.5	1.0	1.6	-1.1	-1.3	0.6
Medication: Ramipril	0.5	0.7	1.4	-0.7	-0.4	-1.2
Trunk fat-free mass	0.5	3.0	3.5	1.6	1.9	1.7
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.7	0.8	0.9	0.9	-0.7
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	3.6	1.4	1.9	-0.3
Trunk predicted mass	0.5	3.0	3.7	1.7	1.9	1.6
Exposure to tobacco smoke at home	0.5	0.5	0.8	-0.9	-0.6	-0.6
Headache pain in last month	0.5	0.8	1.4	-1.2	-1.0	-0.2
Shortness of breath walking on level ground	0.5	0.5	0.8	0.8	0.9	-0.5
Mouth/teeth dental problems: Loose teeth	0.5	0.6	0.6	-0.8	-0.7	-0.8
Neck or shoulder pain in last month	0.5	0.8	2.2	0.3	0.1	-1.5
Medication: Ibuprofen	0.5	0.6	1.0	0.9	1.0	-0.3
Illnesses of father: Heart disease	0.5	0.7	0.8	-0.8	-0.8	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.6	1.1	-0.8	-0.3	1.0
Supplements: Fish oil (including cod liver oil)	0.5	0.7	2.0	-0.1	-0.2	1.4
Illnesses of father: High blood pressure	0.5	0.7	1.9	-0.0	0.1	-1.4
Depressed Affect (Nagel 2018)	0.4	0.9	2.7	-0.0	0.2	-1.6
Depression (Nagel 2018)	0.4	0.6	1.6	0.4	0.3	-1.3
Reaction Time	0.4	0.8	1.5	-1.0	-1.2	-0.2
Smoking Status	0.4	1.0	1.3	0.8	1.2	1.0
Respiratory disease	0.4	0.9	1.1	-0.9	-1.0	-1.0
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.1	0.6	0.8	-1.1
Chronotype (morning person)	0.4	1.0	1.2	1.0	0.8	-1.1
Townsend deprivation index at recruitment	0.4	0.6	1.1	-0.6	-0.6	-1.1
Average weekly fortified wine intake	0.4	0.5	0.8	0.7	0.6	0.9
Qualifications: CSEs or equivalent	0.4	0.6	1.5	0.0	0.5	-1.2
Stomach or abdominal pain in last month	0.4	0.5	0.8	-0.5	-0.6	0.9
High blood pressure (mother)	0.4	0.6	1.0	-0.8	-0.5	-1.0
Falls in the last year	0.4	0.6	1.1	1.0	0.8	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	0.9	0.8	1.0	-0.0
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	0.9	-0.6	-1.0	0.8
Heart disease (mother)	0.4	0.5	1.5	0.2	0.4	1.2
Alcohol intake frequency.	0.4	0.9	2.0	-0.6	-0.5	1.4
Number of full sisters	0.4	0.5	1.4	-0.3	-0.2	1.2
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.8	0.4	0.7	0.9
Whole body fat-free mass	0.4	2.1	2.5	1.3	1.6	1.4
Back pain experienced in last month	0.4	0.6	0.9	0.7	0.6	-0.9
Whole body water mass	0.4	2.0	2.3	1.2	1.5	1.5
Arm fat-free mass (left)	0.4	2.0	2.3	1.2	1.5	1.4
Irritability	0.4	0.7	0.9	0.9	0.6	-0.9
Fractured/broken bones in last 5 years	0.4	0.5	1.0	0.5	0.4	1.0
Pain experienced in last month	0.4	0.6	1.0	1.0	0.8	0.6
Arm predicted mass (left)	0.4	1.9	2.2	1.2	1.5	1.5
Ulcerative Colitis (UC)	0.3	0.6	0.9	0.8	1.0	-0.5
Breast Cancer	0.3	0.7	1.8	0.3	0.3	1.3
Ovarian Cancer	0.3	0.3	0.5	0.6	0.7	-0.4
Triglycerides	0.3	0.5	0.9	-0.8	-1.0	-0.4
Allergy or Eczema	0.3	0.8	2.3	-0.0	-0.3	1.5
Hearing difficulty/problems: Yes	0.3	0.5	0.9	-0.7	-0.3	-0.9
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.7	0.3	0.3	0.8
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.8	0.1	0.2	-0.9
High blood pressure	0.3	0.8	1.7	0.4	0.7	-1.3
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.8	0.4	0.1	1.4
Impedance of leg (left)	0.3	1.5	2.2	-1.1	-1.0	-1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	0.9	-0.8	-0.9	-0.9
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.0	0.3	0.2	1.0
Fluid intelligence score	0.3	0.7	1.2	0.7	0.7	-1.1
Weight	0.3	1.6	3.0	1.2	1.7	0.6
Impedance of arm (right)	0.3	1.5	4.5	0.1	0.2	-2.1
Pulse rate	0.3	0.6	0.9	0.6	0.7	0.9
Noisy workplace	0.3	0.4	0.8	-0.5	-0.4	0.9
Asthma	0.3	0.5	0.5	-0.7	-0.7	-0.7
Impedance of arm (left)	0.3	1.5	4.3	-0.2	-0.3	-2.1
Medication: Amlodipine	0.3	0.5	1.2	-0.4	-0.1	-1.1
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.6	-0.7	-0.8	0.1
Arm fat-free mass (right)	0.3	1.8	2.4	1.1	1.3	1.5
Medication for pain relief, constipation, heartburn	0.3	0.5	1.2	-0.3	-0.4	-1.1
Medication: Allopurinol	0.3	0.4	0.6	-0.6	-0.8	-0.4
Mean time to correctly identify matches	0.3	0.6	0.8	-0.6	-0.9	-0.9
Whole body fat mass	0.3	1.1	2.3	1.0	1.5	-0.0
Arm predicted mass (right)	0.3	1.7	2.7	0.9	1.2	1.7
Medication: Aspirin	0.3	0.4	1.2	-0.3	-0.2	1.1
Eye problems/disorders: Cataract	0.3	0.3	0.7	0.5	0.8	0.2
Mineral and other dietary supplements	0.3	0.4	0.8	-0.4	-0.3	-0.9
Illnesses of father: None of the above (group 1)	0.3	0.3	0.7	0.8	0.6	-0.0
Miserableness	0.3	0.5	1.3	0.3	0.4	-1.1
Medication: Atorvastatin	0.3	0.4	0.9	0.2	0.3	-1.0
Basal metabolic rate	0.3	1.8	2.6	1.2	1.6	1.1
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.0	0.0	0.1	1.0
Basal cell carcinoma (self-reported)	0.3	0.4	0.5	-0.7	-0.6	0.4
Impedance of whole body	0.3	1.5	4.1	-0.5	-0.5	-2.0
Body Mass Index (BMI) (2010)	0.2	0.2	0.2	-0.5	-0.4	-0.5
Heel T-Score	0.2	1.3	2.3	-1.2	-1.5	0.0
BMI	0.2	1.4	2.9	0.7	1.0	1.7
Medication: Co-codamol	0.2	0.3	0.4	-0.5	-0.6	-0.4
Impedance of leg (right)	0.2	1.0	2.1	-0.7	-0.7	-1.5
Leg fat-free mass (left)	0.2	1.1	1.7	0.9	1.3	0.9
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	0.6	-0.8	-0.8	-0.6
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.3	-0.5	-0.3	0.5
Supplements: Glucosamine	0.2	0.3	0.5	0.6	0.7	-0.3
Diverticular disease/diverticulitis (self-reported)	0.2	0.2	0.5	-0.2	-0.3	-0.7
Body mass index (BMI)	0.2	0.9	1.5	0.9	1.2	0.7
Leg predicted mass (left)	0.2	1.2	1.8	1.0	1.3	0.9
Trunk fat mass	0.2	1.0	2.0	0.9	1.4	0.2
Waist circumference	0.2	0.8	1.5	0.9	1.2	0.1
Number of incorrect matches in round	0.2	0.3	0.7	-0.2	-0.4	-0.8
Alcohol usually taken with meals	0.2	0.3	0.8	0.1	0.3	0.9
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.7	0.2	0.2	-0.9
Medication: Simvastatin	0.2	0.3	0.9	0.2	0.3	-0.9
Arm fat percentage (right)	0.2	1.0	1.8	1.0	1.4	-0.3
Number of live births	0.2	0.3	0.4	0.7	0.4	0.6
Qualifications: A levels/AS levels or equivalent	0.2	0.5	0.7	-0.8	-0.8	0.3
Arm fat mass (right)	0.2	0.8	1.6	0.9	1.2	0.2
Body fat percentage	0.2	0.7	1.5	0.8	1.2	-0.2
Leg fat percentage (right)	0.2	0.7	1.4	0.8	1.2	-0.4
Eye problems/disorders: None of the above	0.2	0.2	0.2	0.5	0.3	-0.5
Medication: Blood pressure	0.2	0.3	0.9	-0.0	0.3	-0.9
Migraine (self-reported)	0.2	0.2	0.6	0.1	0.2	0.8
Hypertension (Self-reported)	0.2	0.5	1.0	0.4	0.6	-1.0
Leg fat-free mass (right)	0.2	0.9	1.3	0.8	1.1	0.8
Arm fat percentage (left)	0.2	0.7	1.4	0.8	1.2	-0.3
Qualifications: nursing, teaching	0.2	0.3	0.9	-0.1	0.2	1.0
Medication for cholesterol	0.2	0.3	0.7	0.4	0.2	0.8
Medication: Gliclazide	0.2	0.2	0.5	-0.7	-0.5	-0.0
Arm fat mass (left)	0.2	1.0	1.9	1.0	1.4	-0.0
Number of self-reported non-cancer illnesses	0.2	0.4	0.7	-0.8	-0.6	-0.1
Mother’s age at death	0.2	0.2	0.4	-0.3	-0.4	-0.6
Medication: Blood pressure	0.2	0.4	1.0	-0.3	-0.0	-1.0
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.7	0.0	-0.1	-0.8
Ever smoked	0.2	0.3	0.8	0.1	0.3	0.9
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.5	-0.0	-0.3	1.2
Supplements: Calcium	0.2	0.2	0.7	-0.1	-0.1	-0.8
Bipolar Disorder (2018)	0.1	0.1	0.2	-0.3	-0.2	-0.5
Lupus	0.1	0.2	0.4	-0.6	-0.5	-0.2
Ulcerative Colitis	0.1	0.2	0.3	0.3	0.6	0.5
Waist Hip Ratio (WHR)	0.1	0.4	0.7	0.6	0.4	-0.8
Cardiovascular Disease	0.1	0.4	0.8	0.3	0.5	-0.9
Lung FEV1/FVC ratio	0.1	0.3	0.4	-0.6	0.3	0.7
Hair Pigment	0.1	1.5	1.8	-1.4	-1.1	-1.2
Relative age of first facial hair	0.1	0.2	0.2	0.5	0.2	0.5
Systolic blood pressure, automated reading	0.1	0.2	0.2	0.5	0.5	-0.4
Vitamin and mineral supplements	0.1	0.1	0.4	-0.1	-0.2	-0.6
Diabetes (mother)	0.1	0.2	0.4	0.2	0.1	0.6
Trunk fat percentage	0.1	0.6	1.2	0.7	1.1	-0.2
Current tobacco smoking	0.1	0.1	0.3	-0.3	-0.0	-0.5
Maternal smoking around birth	0.1	0.2	0.2	-0.5	-0.2	-0.5
Taking other prescription medications	0.1	0.1	0.1	0.2	0.3	-0.4
Medication: Atenolol	0.1	0.1	0.2	0.1	0.0	-0.4
Sitting height	0.1	0.4	0.7	0.7	0.8	0.3
Past tobacco smoking	0.1	0.2	0.4	-0.4	-0.6	-0.4
Heart attack	0.1	0.1	0.3	-0.0	-0.1	0.5
Allergy	0.1	0.2	0.4	0.4	0.6	-0.2
Time employed in main current job	0.1	0.1	0.1	0.1	0.4	-0.4
Alcohol intake versus 10 years previously	0.1	0.1	0.2	-0.4	-0.4	0.2
Hair/balding pattern: Pattern 3	0.1	0.2	0.4	-0.2	-0.3	0.7
Illnesses of mother	0.1	0.1	0.2	-0.3	-0.4	0.3
Standing height	0.1	1.1	2.0	1.1	1.4	0.3
Length of working week for main job	0.1	0.1	0.2	-0.1	-0.2	0.5
Peak expiratory flow (PEF)	0.1	0.3	0.7	0.4	0.9	0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.2	-0.4	-0.4	0.4
Blood clot in the leg (DVT)	0.1	0.1	0.2	-0.0	-0.1	-0.5
Wheeze or whistling in the chest in last year	0.1	0.3	0.4	-0.6	-0.5	0.4
Health satisfaction	0.1	0.1	0.1	0.3	0.4	-0.3
Leg fat mass (right)	0.1	0.5	1.3	0.6	1.1	0.1
Pulse rate, automated reading	0.1	0.4	0.4	-0.6	-0.6	0.7
Comparative height size at age 10	0.1	0.3	0.4	0.3	0.6	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.2	0.3	0.4	0.4
Supplements: Vitamin C	0.1	0.2	0.2	-0.5	-0.5	0.1
Smoking status: Previous	0.1	0.2	0.2	0.3	0.4	0.5
Mood swings	0.1	0.3	0.7	-0.2	-0.2	-0.8
Asthma (self-reported)	0.1	0.3	0.3	-0.5	-0.5	-0.5
Leg predicted mass (right)	0.1	0.8	1.1	0.7	1.0	0.9
Leg fat percentage (left)	0.1	0.4	0.8	0.5	0.9	-0.3
Diastolic blood pressure, automated reading	0.1	0.2	0.3	0.4	0.6	-0.4
Heart attack/myocardial infarction (self-reported)	0.1	0.2	0.5	0.0	-0.0	0.7
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.5	0.0	-0.1	-0.7
Alcohol drinker status: Previous	0.1	0.1	0.3	-0.2	-0.1	-0.6
Leg fat mass (left)	0.1	0.3	0.8	0.4	0.9	-0.0
Alzheimer’s Disease (including proxy)	0.0	0.0	0.0	0.2	0.0	0.1
Age at First Birth	0.0	0.0	0.0	-0.2	0.0	-0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
Height	0.0	0.4	0.9	0.5	1.0	0.1
Tanning	0.0	0.4	0.5	0.7	0.7	0.5
Number of treatments/medications taken	0.0	0.1	0.2	-0.5	-0.2	-0.1
Hip circumference	0.0	0.2	0.4	0.2	0.6	-0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.1	0.1	0.3	0.2	-0.0
Qualifications: College or University degree	0.0	0.0	0.0	0.1	-0.1	0.0
Had major operations	0.0	0.0	0.1	0.3	-0.0	-0.0
Knee pain experienced in last month	0.0	0.0	0.0	0.0	0.0	-0.2
Average weekly red wine intake	0.0	0.0	0.0	-0.2	0.2	0.2
Smoking status: Current	0.0	0.0	0.1	0.0	0.4	-0.1
Commuting to job workplace: Cycle	0.0	0.0	0.1	0.2	0.2	0.0

Hub : Genes

SCGB3A1

Models

Trait associations