Hub : Genes

SCIMP

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1130	0.0570	5.1e-03	0.013	NA	0.015	NA	0.015	2.8e-02	NA	2.1e-02	NA	2.0e-02
2	GTEx	Artery Tibial	0.1039	0.0457	9.3e-03	0.012	NA	0.016	NA	0.027	3.4e-02	NA	1.7e-02	NA	3.1e-03
3	GTEx	Brain Frontal Cortex BA9	0.3376	0.0968	1.8e-03	0.006	NA	-0.008	NA	0.004	2.2e-01	NA	5.9e-01	NA	2.5e-01
4	GTEx	Esophagus Muscularis	0.0960	0.0430	2.9e-03	0.015	NA	0.034	NA	0.021	4.2e-02	NA	3.7e-03	NA	1.9e-02
5	GTEx	Nerve Tibial	0.1645	0.0777	2.5e-03	0.051	NA	0.025	NA	0.035	1.8e-04	NA	6.2e-03	NA	1.5e-03
6	GTEx	Spleen	0.3420	0.1420	9.4e-03	0.020	NA	0.083	NA	-0.006	9.9e-02	NA	3.8e-03	NA	4.7e-01
7	GTEx	Thyroid	0.1140	0.0490	2.8e-03	0.035	NA	0.023	NA	0.049	1.1e-03	NA	6.3e-03	NA	1.2e-04
8	GTEx	Whole Blood	0.0920	0.0380	7.1e-03	-0.002	NA	0.005	NA	-0.002	6.0e-01	NA	1.0e-01	NA	6.1e-01
9	ROSMAP	Brain Pre-frontal Cortex	0.0705	0.0237	2.4e-05	0.084	0.045	0.062	0.061	0.065	6.8e-11	1.5e-06	1.9e-08	2.8e-08	8.1e-09

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	1.6	2.5	6.0	-2.3	-2.5	0.5	-0.7	-1.1	-0.1	-1.7	-2.1	-1.6
Bipolar Disorder or Schizophrenia	0.9	2.2	6.6	-1.8	-1.4	-1.0	-1.6	-1.4	-0.6	-2.6	-0.7	-1.4
Depressed Affect (Nagel 2018)	0.5	1.1	3.9	-0.3	0.6	1.6	0.0	-1.1	-2.0	0.1	-0.6	-1.0
Depression (Nagel 2018)	0.6	1.0	3.0	-0.2	1.4	1.7	-0.2	-1.3	-0.8	-0.4	-0.2	-1.0
Intelligence (Savage-Jansen 2018)	0.2	0.7	4.6	-0.7	-0.6	-2.2	0.4	0.1	0.2	-0.3	-0.7	-0.1
Neuroticism (Nagel 2018)	0.7	1.6	5.1	-1.3	0.6	2.3	-0.6	-1.6	-1.3	-0.8	-0.7	-1.4
Schizophrenia (2018)	0.6	1.3	3.9	-0.6	0.1	-1.6	-1.5	-0.9	-0.7	-2.0	0.9	-0.5
Schizophrenia vs Biploar Disorder	0.8	1.1	3.3	1.4	1.8	0.6	-1.4	0.7	-0.2	-0.1	0.8	1.0
Worry (Nagel 2018)	0.4	0.9	3.7	-0.5	1.7	1.9	-0.2	-0.8	0.0	-0.4	0.6	-0.5
Alzheimer’s Disease (in mother)	3.7	4.3	11.5	3.3	1.7	-0.7	2.6	1.6	-1.3	3.4	0.7	1.4
Alzheimer’s Disease (in father)	2.6	2.8	6.3	2.3	2.5	0.1	1.3	2.1	0.1	2.0	1.1	1.5
Alzheimer’s Disease (including proxy)	5.6	8.1	20.1	4.1	2.4	-0.9	3.4	3.3	-0.3	4.5	1.0	2.4
Crohns Disease (2017)	0.4	0.8	3.4	1.8	0.4	-0.2	0.7	1.0	0.6	1.1	-0.2	0.8
Irritable Bowel Disease (IBD)	0.2	0.4	1.2	0.4	0.1	0.9	-0.3	-0.2	-1.1	0.3	-0.8	-0.7
Ulcerative Colitis (UC)	0.9	1.6	4.0	-1.0	-0.4	1.8	-1.0	-1.1	-2.0	-0.3	-1.2	-1.6
Major Depression (MDD)	0.5	0.5	1.7	-0.6	-0.6	-0.4	0.9	-0.9	-0.7	0.3	-0.2	-1.3
Reaction Time	1.5	2.8	6.9	2.0	2.1	2.3	0.6	1.6	-0.2	2.6	0.1	1.4
Verbal and Numeric Reasoning (VNR)	0.7	1.6	4.6	0.6	0.4	-2.1	1.5	1.0	1.8	0.5	1.2	1.2
Breast Cancer	0.5	1.3	3.3	-1.8	-1.5	1.5	-0.9	-1.0	-0.1	-0.8	-0.7	-0.8
Ovarian Cancer	0.1	0.1	0.4	-0.4	0.4	-0.0	-0.0	0.2	0.6	-0.0	0.2	0.3
Prostate Cancer	0.8	1.2	2.3	1.3	0.6	-1.4	-0.1	1.1	1.5	0.2	1.4	1.0
Age at First Birth	0.6	0.9	3.5	0.2	0.7	1.9	-0.7	0.2	1.6	-0.8	-0.3	-0.1
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	1.2	1.7	5.4	1.6	0.5	-0.1	1.9	1.2	-0.2	2.3	0.8	0.9
Coronary Artery Disease (CAD)	0.6	0.7	1.8	0.7	0.2	0.5	-0.6	-0.8	-0.8	-1.1	1.4	-1.0
Crohns Disease (2012)	0.5	0.9	2.8	0.5	0.5	0.8	-1.7	-0.9	-0.1	-0.9	-1.1	-1.1
Mean Putamen Volume	1.2	1.3	4.2	-1.6	-2.1	0.7	0.7	-0.2	0.2	0.1	-2.0	-0.3
Fasting Glucose	0.7	0.9	2.2	0.3	0.4	-0.5	1.2	1.2	0.2	1.1	-1.5	1.1
HbA1C	0.1	0.1	0.3	-0.5	-0.1	0.1	-0.3	0.1	-0.2	-0.5	-0.1	0.0
HDL Cholesterol	0.4	0.6	3.2	0.5	0.2	-0.5	1.0	0.6	-0.5	1.8	-0.2	0.1
LDL Cholesterol	0.3	0.5	2.5	-0.5	0.6	0.4	-0.8	-0.5	-1.6	-0.6	0.4	0.2
Lupus	1.0	1.5	6.0	0.4	1.0	0.1	1.0	1.3	1.2	0.3	2.5	1.5
Neuroticism (2016)	0.6	0.9	1.8	-0.7	0.8	1.3	-0.5	-1.3	-0.6	-0.6	-1.0	-1.1
Primary Biliary Cirrhosis	1.3	1.9	4.7	-1.5	-1.0	-0.5	-2.2	-1.4	-1.7	-1.2	-0.8	-1.4
Rheumatoid Arthritis	1.8	2.5	6.4	-0.1	-0.6	-1.2	1.5	2.1	2.5	0.8	1.8	2.0
Schizophrenia (2014)	1.5	3.2	10.5	-1.2	0.2	-1.1	-3.2	-1.7	-1.4	-3.1	0.4	-1.2
Triglycerides	0.1	0.1	0.6	-0.4	-0.4	-0.2	-0.3	-0.1	-0.5	-0.8	0.1	-0.2
Type 2 Diabetes (T2D) (2012)	1.3	1.5	3.0	1.7	1.3	0.5	1.1	1.2	1.5	0.4	1.7	1.1
Ulcerative Colitis	0.7	1.1	3.5	-0.4	-0.1	0.9	-1.4	-0.8	-1.9	-0.6	-0.8	-1.3
Blood Eosinophil Count	0.7	5.4	9.9	1.4	1.2	-0.7	3.1	3.1	1.8	2.8	2.3	3.0
Blood Platelet Count	0.9	10.3	25.4	2.9	0.1	0.4	4.6	1.6	3.6	5.0	-4.7	-0.3
Blood Red Count	0.5	5.0	10.0	2.5	1.0	0.1	3.1	2.7	0.8	3.2	-1.1	3.0
Blood White Count	5.1	37.5	95.5	6.8	5.3	-0.1	8.7	7.0	2.7	9.8	2.5	5.5
Heel T-Score	1.2	9.5	21.3	1.7	2.6	-0.1	3.1	4.6	3.3	2.7	2.6	4.4
BMI	1.2	7.0	22.6	3.2	2.2	0.2	3.8	2.8	-0.3	4.8	0.5	1.6
Height	0.1	2.0	7.6	-1.4	-2.1	1.6	0.1	-0.5	-0.7	-0.1	-2.8	-0.8
Waist Hip Ratio (WHR)	0.1	0.7	2.9	0.4	0.1	1.7	-0.1	0.0	-1.2	0.1	-1.1	0.4
Systolic Blood Pressure	0.4	1.8	9.1	0.6	0.9	3.0	-1.4	0.4	0.9	-1.2	0.8	0.9
Smoking Status	0.3	0.6	2.2	-0.5	-1.5	-0.5	0.7	1.2	-0.2	-0.0	0.7	0.7
Allergy or Eczema	0.4	1.0	2.9	0.3	0.1	-0.4	0.8	1.6	1.3	0.6	0.2	1.7
Cardiovascular Disease	0.2	0.7	3.3	0.1	1.1	1.8	-0.9	-0.3	-0.1	-0.5	0.6	0.1
Hypothyroidism (self reported)	0.3	0.7	2.7	-0.1	-1.0	-0.4	-0.2	0.3	1.6	-0.2	1.6	0.4
Respiratory disease	0.4	0.8	4.2	-0.4	-1.2	2.0	0.8	-0.3	0.2	0.1	-0.8	-0.5
Type 2 Diabetes (T2D) (2018)	0.5	1.0	4.1	0.8	0.3	0.9	2.0	0.6	-0.1	1.7	-0.2	0.1
Lung FEV1/FVC ratio	0.1	0.4	1.7	-0.3	-0.7	-1.3	-0.8	0.5	-0.3	-0.5	-0.3	0.6
Lung FVC	0.2	0.9	2.9	-1.0	-0.8	-0.5	1.0	1.2	1.7	0.1	-0.5	0.9
Neuroticism	0.7	1.6	8.2	-0.9	0.7	2.9	-0.3	-1.2	-1.3	-0.3	-0.9	-1.0
Chronotype (morning person)	1.4	3.3	6.7	-2.6	-0.9	2.0	-1.9	-1.9	-0.9	-2.0	-1.7	-1.8
Hair Pigment	0.1	3.4	5.9	-2.3	-2.1	0.8	-1.5	-2.4	-2.1	-1.3	-1.1	-2.1
Tanning	0.1	1.5	4.8	1.1	-0.1	0.4	1.1	1.7	2.2	-0.1	1.1	1.4
Hand grip strength (left)	1.2	3.2	7.8	0.4	-0.9	-0.5	2.3	2.5	2.8	1.6	0.5	2.4
Number of treatments/medications taken	0.2	0.4	1.4	-0.7	-0.5	0.1	0.1	-1.0	-0.8	0.0	-0.2	-1.2
Average weekly spirits intake	0.3	0.4	1.7	-0.3	-0.8	0.1	-0.7	0.3	0.5	-0.4	-1.3	-0.2
Sensitivity / hurt feelings	0.7	1.2	8.6	-0.6	0.0	2.9	-0.1	-1.0	0.1	-0.6	-0.3	-0.9
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.4	-0.5	0.6	1.6	0.0	-0.7	0.0	-0.1	-0.7	-1.0
Hearing difficulty/problems: Yes	1.4	2.2	7.6	-1.1	-0.7	2.8	-1.4	-1.6	-1.2	-0.5	-0.9	-1.9
Relative age of first facial hair	0.4	0.9	2.2	0.4	0.8	-0.7	-1.4	0.2	0.4	-1.2	1.5	0.7
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.4	0.1	0.4	0.3	0.0	1.0	1.2	-0.0	1.0	0.3
Ever used hormone-replacement therapy (HRT)	6.5	8.3	12.2	-3.5	-2.3	-0.2	-3.4	-3.3	-2.6	-3.0	-3.1	-3.1
Ever had hysterectomy (womb removed)	1.0	1.1	2.7	-1.2	-1.4	0.9	-0.2	-1.6	-0.1	-0.6	-0.7	-1.5
Systolic blood pressure, automated reading	0.3	0.7	3.7	0.0	1.0	1.9	-0.9	0.3	0.4	-0.6	0.7	0.4
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	1.1	-1.0	-0.5	0.7	0.7	-0.2	-0.1	-0.2	-0.3	-0.7
Angina	1.2	1.6	3.0	-1.7	-0.8	1.3	-1.3	-1.1	-0.3	-1.6	-1.3	-1.5
Medication for hormone replacement therapy	1.4	1.5	3.4	-1.2	-1.8	-1.2	-0.1	-1.2	-0.3	-0.7	-1.8	-1.5
Vitamin and mineral supplements	0.4	0.5	1.5	-0.8	-0.9	-1.2	0.7	0.2	-0.0	-0.1	-1.0	0.4
Supplements: Zinc	1.3	1.4	3.0	0.0	-1.1	-1.7	-0.2	-1.1	-1.5	-0.6	-1.6	-1.5
Medication: Co-codamol	0.8	0.9	3.6	-0.1	0.4	1.9	0.8	0.0	-1.3	0.9	-1.1	-0.4
Medication: Metformin	0.7	1.0	5.7	-0.4	-0.0	1.1	2.4	0.3	0.3	1.3	-0.0	-0.3
Diabetes (father)	0.2	0.2	0.6	0.5	-0.2	-0.1	0.3	0.8	0.3	0.4	0.1	0.7
Diabetes (mother)	0.4	0.5	2.3	-0.1	-1.3	-1.5	0.4	-0.0	-0.2	-0.1	-0.6	-0.0
Severe depression (siblings)	0.3	0.3	1.8	0.1	0.0	-0.4	0.6	-0.1	-0.7	0.1	-1.4	-0.4
Pack years adult smoking proportion	1.1	1.7	3.0	-1.7	-1.3	1.5	-1.3	-1.1	-1.1	-1.6	-1.1	-0.7
Impedance of leg (right)	0.1	0.6	2.0	0.2	1.0	0.8	-1.4	-0.7	0.1	-1.0	0.2	0.5
Leg fat-free mass (left)	0.7	3.9	13.6	1.2	-0.1	-1.1	3.7	2.6	0.4	3.1	-0.1	1.5
Trunk fat percentage	0.9	3.6	13.5	1.7	1.3	-0.8	3.0	1.8	-0.1	3.7	-0.4	1.2
Hand grip strength (right)	1.3	3.6	7.9	1.2	-0.0	-0.9	2.3	2.8	2.5	2.0	-0.1	2.6
Townsend deprivation index at recruitment	1.0	1.4	2.3	-1.5	-1.4	-0.1	-1.0	-1.2	-1.4	-1.0	-0.9	-1.3
Current tobacco smoking	0.1	0.2	0.8	0.3	0.9	0.4	0.4	0.4	-0.2	-0.1	0.4	0.5
Average weekly fortified wine intake	0.6	0.8	3.2	1.1	1.8	0.3	0.3	0.3	0.5	1.1	0.7	0.5
Maternal smoking around birth	0.4	0.6	2.5	0.5	0.4	-0.7	0.2	-0.8	-1.6	0.4	1.0	-0.5
Fed-up feelings	0.9	1.7	5.2	-1.2	-0.9	1.3	-0.1	-0.8	-2.3	-0.2	-2.0	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	2.6	-0.6	0.7	0.9	-0.6	-1.6	-1.4	-0.7	-1.2	-1.5
Relative age voice broke	0.3	0.4	1.7	0.1	0.3	1.3	-1.1	0.6	-0.2	0.1	0.3	0.6
Taking other prescription medications	0.4	0.7	2.1	-1.4	-0.4	-0.2	-1.0	-0.9	-0.6	-0.9	0.6	-0.8
Age when periods started (menarche)	2.9	6.9	14.1	-3.8	-2.3	2.8	-3.0	-2.4	-2.6	-2.6	-1.1	-2.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.4	0.9	0.8	0.4	1.2	-0.1	0.3	0.8	-0.2	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.3	0.2	0.5	-0.4	0.9	1.5	0.1	1.0	0.0	1.2
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	4.8	1.1	0.7	-2.2	0.9	0.6	-0.8	1.3	0.6	0.2
Qualifications: CSEs or equivalent	0.8	1.0	2.4	1.6	0.9	0.7	0.4	0.7	-1.2	1.5	0.9	0.5
Serious illness, injury or assault to yourself	1.0	1.2	2.8	1.4	1.6	0.4	0.9	-0.1	-0.9	1.7	0.9	-0.5
High blood pressure	0.2	0.5	1.0	-0.1	0.9	0.9	-0.9	-0.8	-0.1	-0.8	1.0	-0.2
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.4	0.3	0.1	-0.1	0.3	0.5	0.5	0.4	-0.6	0.3
Multivitamins +/- minerals	0.5	0.6	1.7	0.9	1.3	0.8	-0.3	0.4	0.6	0.5	1.0	0.3
Stomach or abdominal pain in last month	0.5	0.6	1.3	-0.4	1.1	1.0	-0.2	-1.0	-1.1	-0.4	0.2	-1.0
Supplements: Glucosamine	0.3	0.4	0.6	-0.6	-0.6	0.7	-0.8	-0.5	-0.4	-0.6	-0.4	-0.8
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.7	-0.3	-1.3	0.6	-0.7	0.0	0.5	-0.4	-0.6	-0.0
Medication: Atenolol	0.8	1.0	3.6	-0.1	0.9	0.3	0.4	-1.9	-1.4	-0.5	-0.7	-1.2
Medication: Levothyroxine sodium	0.4	0.7	3.6	-0.1	-0.5	-0.4	-0.2	0.3	1.9	-0.1	1.5	0.1
Sitting height	0.1	0.6	1.6	-0.3	-0.8	0.3	1.1	1.3	-0.2	0.8	-0.6	0.9
Chronic bronchitis/emphysema (father)	0.5	0.6	1.7	0.3	0.5	-0.8	0.6	1.1	0.2	1.3	0.2	0.8
High blood pressure (mother)	0.4	0.5	3.2	0.1	1.8	-0.5	-0.5	0.1	-0.5	-0.4	0.4	0.4
Body mass index (BMI)	1.0	4.2	13.5	2.0	1.3	-0.4	3.3	2.4	0.2	3.7	-0.1	1.4
Impedance of leg (left)	0.1	0.6	2.5	0.1	0.9	0.8	-1.6	-0.5	0.0	-0.8	0.3	0.4
Leg predicted mass (left)	0.8	4.1	14.1	1.3	-0.1	-1.0	3.8	2.7	0.5	3.1	-0.1	1.6
Trunk fat mass	1.1	4.7	16.3	1.8	1.1	-0.7	3.7	2.3	0.1	4.0	-0.4	1.4
Waist circumference	0.8	2.9	8.7	1.4	0.9	-0.2	2.9	2.1	-0.3	3.0	-0.3	1.4
Number of incorrect matches in round	0.3	0.5	1.7	-0.2	0.7	0.7	-1.3	-0.3	1.0	-0.9	-0.5	-0.1
Past tobacco smoking	1.1	2.0	10.1	2.0	3.2	1.2	0.0	-1.2	-0.2	0.9	-0.0	-0.4
Alcohol usually taken with meals	1.5	2.5	4.4	1.3	1.1	2.1	0.9	1.6	2.0	1.3	1.5	2.0
Nervous feelings	1.3	2.5	7.6	-0.9	0.7	1.2	-2.8	-2.2	-0.5	-2.0	-0.6	-1.6
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.5	8.5	-0.9	0.0	1.1	-1.1	-2.8	-2.2	-1.3	-2.2	-2.9
Hearing difficulty/problems with background noise	1.2	2.0	9.0	1.1	1.9	3.0	-1.1	-0.5	-1.0	0.5	0.9	-0.6
Hair/balding pattern: Pattern 2	0.3	0.4	1.1	0.4	-0.7	0.8	0.2	0.7	0.7	0.0	0.4	1.0
Had menopause	3.9	4.9	11.2	-2.8	-1.5	-0.2	-2.8	-2.5	-0.2	-3.3	-1.8	-2.4
Had other major operations	0.2	0.3	0.9	0.6	0.5	1.0	0.3	-0.5	0.2	0.4	0.1	-0.7
Forced vital capacity (FVC)	0.6	2.2	7.7	0.4	-0.9	-0.7	1.4	2.8	1.3	1.0	0.5	2.5
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.5	-0.1	-0.2	-0.3	0.2	1.2	-0.2	0.1	-0.3	1.0
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	1.9	-0.5	0.1	0.1	-0.3	-1.3	-1.1	-0.1	-1.3	-1.4
Qualifications: None of the above	2.0	4.4	9.1	-2.0	-1.7	-2.1	-1.6	-3.0	-2.2	-1.6	-1.1	-2.8
Financial difficulties in last 2 years	1.9	2.5	5.7	1.7	1.0	-1.8	2.2	1.6	0.9	2.4	1.0	0.9
Mouth/teeth dental problems	1.2	1.9	5.6	1.0	-0.2	0.0	0.7	2.4	1.3	0.9	1.8	2.1
Heart attack	0.8	1.0	2.0	-0.9	-0.7	0.2	-1.4	-0.9	-1.4	-0.9	-1.3	-0.9
Allergy	0.1	0.2	1.5	-0.1	0.5	-0.3	-0.4	-0.3	-1.2	-0.1	0.1	0.1
Pain all over the body in last month	0.7	0.8	2.9	0.3	0.7	-1.2	0.5	-0.6	-0.7	0.3	-1.7	-1.0
Diabetes (self-reported)	0.7	1.1	5.6	-0.4	-0.0	1.0	2.4	0.8	0.2	1.5	-0.2	0.2
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.9	-1.0	-0.8	0.1	0.5	-0.1	0.4	-0.3	-0.8	0.0
Medication: Ramipril	1.2	1.5	4.1	-0.9	0.3	1.3	-0.8	-1.9	-1.6	-0.5	-0.4	-2.0
Medication: Simvastatin	1.3	1.9	3.3	-1.6	-0.6	0.5	-1.1	-1.8	-1.2	-1.8	-1.2	-1.8
Fluid intelligence score	1.0	2.1	5.8	0.0	-0.5	-2.0	2.4	1.7	1.6	1.0	-0.0	1.6
Illnesses of siblings	2.1	2.9	7.0	2.0	1.7	0.0	1.0	2.4	1.4	1.5	1.2	2.7
Neuroticism score	0.7	1.4	9.2	-0.2	1.0	3.0	0.1	-0.7	-1.0	0.1	-0.6	-0.8
Weight	0.9	4.4	13.8	1.6	0.7	-0.4	3.6	2.6	0.2	3.7	-0.4	1.6
Impedance of arm (right)	0.2	0.8	3.0	0.6	1.0	0.5	-0.9	-1.7	-0.3	-0.5	0.3	-0.9
Arm fat percentage (right)	1.2	4.7	15.9	2.4	1.8	-0.6	3.4	2.1	0.2	4.0	0.0	1.3
Trunk fat-free mass	0.6	3.3	10.4	1.2	-0.3	-0.6	3.2	2.8	0.8	2.4	-0.1	1.9
Hip circumference	1.1	4.9	11.8	1.8	1.4	-1.3	3.4	2.9	0.7	3.4	0.7	2.0
Time employed in main current job	0.2	0.2	0.7	-0.6	-0.1	0.5	-0.9	0.2	0.3	-0.6	-0.3	0.3
Alcohol intake versus 10 years previously	1.1	1.6	5.2	-0.4	-2.1	-1.1	2.3	0.3	0.0	1.4	-1.0	-0.3
Father’s age at death	0.2	0.3	1.1	-0.4	-0.6	1.0	-0.6	0.0	-0.3	0.0	-0.8	0.2
Worrier / anxious feelings	0.6	1.1	4.0	0.2	1.2	2.0	0.9	0.6	1.6	0.4	0.5	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.5	-0.4	0.8	0.8	0.3	-1.0	-1.1	-0.0	-0.6	-1.2
Falls in the last year	0.8	1.0	3.6	0.2	1.2	0.1	-0.5	-1.2	-1.9	0.3	0.9	-1.4
Hair/balding pattern: Pattern 3	1.9	2.8	4.6	2.1	2.0	-0.1	1.6	1.6	1.0	2.1	1.8	1.6
Number of live births	0.9	1.2	4.1	-0.2	-0.7	-0.0	-0.5	-1.9	-2.0	-0.5	-0.0	-1.5
Forced expiratory volume in 1-second (FEV1)	1.1	3.6	12.0	1.0	-0.2	-0.8	1.6	3.5	1.5	1.6	0.8	3.3
Pulse rate	0.9	1.5	4.0	-1.6	-1.3	2.0	-0.4	-0.9	-0.4	-0.3	-1.3	-1.5
Happiness	1.9	2.3	5.2	-1.3	-0.8	-0.5	-1.9	-1.8	-0.6	-2.3	-0.7	-2.2
Noisy workplace	0.6	0.8	3.6	0.0	0.1	-1.9	-1.1	-0.6	-1.0	-0.1	-0.2	-0.7
Qualifications: A levels/AS levels or equivalent	0.5	1.2	3.0	0.8	0.2	-0.8	1.7	1.5	0.2	1.0	0.7	1.5
Serious illness, injury or assault of a close relative in last 2 years	1.7	2.0	4.3	2.0	0.6	-1.8	-0.3	2.1	0.4	0.8	0.7	2.1
Mouth/teeth dental problems: Dentures	1.8	3.0	7.4	-1.6	-0.2	-0.4	-1.1	-2.4	-2.0	-1.3	-2.7	-2.0
Asthma	0.3	0.6	2.5	0.2	-0.3	1.6	0.6	0.5	1.2	0.4	0.7	0.3
Medication: Ibuprofen (e.g. Nurofen)	1.9	2.5	5.3	0.9	-0.1	-2.3	1.9	1.9	-0.1	2.0	1.2	1.8
Medication: Cholesterol lowering	0.7	1.1	2.6	-1.6	-0.5	0.3	-0.6	-1.3	-1.2	-1.4	-0.7	-0.9
Depression (self-reported)	0.2	0.2	0.8	0.3	0.7	0.5	0.2	0.1	0.9	0.6	-0.1	0.1
Medication: Lansoprazole	0.3	0.4	0.7	0.8	0.8	0.2	0.6	0.8	0.5	-0.0	0.7	0.5
Prospective memory result	3.6	4.5	10.3	-2.2	-0.9	0.9	-3.2	-2.3	-2.1	-2.7	-0.8	-2.4
Lung cancer (father)	1.6	1.9	6.3	0.7	0.0	-0.7	0.1	2.5	1.0	0.5	1.6	2.4
Illnesses of mother	0.1	0.2	0.7	0.5	-0.3	0.2	0.6	-0.1	0.8	0.1	-0.0	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.8	9.2	0.2	-0.5	-0.8	1.4	3.0	1.9	0.8	0.7	2.9
Pulse wave Arterial Stiffness index	0.1	0.2	0.5	-0.4	-0.5	-0.7	0.3	0.1	-0.1	0.3	-0.7	-0.1
Impedance of arm (left)	0.2	0.9	2.9	0.1	1.1	0.7	-1.4	-1.7	-0.6	-0.8	0.4	-0.9
Arm fat mass (right)	1.1	4.6	15.7	2.0	1.0	-1.0	3.6	2.2	-0.1	4.0	-0.4	1.1
Trunk predicted mass	0.5	3.0	9.5	1.1	-0.4	-0.6	3.1	2.6	0.7	2.3	-0.3	1.7
Standing height	0.1	0.7	1.8	-0.6	-1.4	-0.1	1.2	1.0	0.1	0.7	-1.0	0.7
Length of working week for main job	0.7	0.8	1.7	1.0	0.6	1.2	1.1	1.0	0.2	1.3	0.3	0.5
Exposure to tobacco smoke at home	0.5	0.6	1.5	-0.3	0.1	1.0	-0.1	-0.6	-1.2	0.3	-1.2	-1.0
Breastfed as a baby	0.3	0.3	1.0	-0.0	-1.0	0.4	-0.7	-0.1	-0.9	0.0	-0.7	-0.4
Tense / ‘highly strung’	2.4	4.0	6.8	-2.6	-0.5	1.7	-2.3	-2.1	-1.8	-2.1	-2.1	-2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	2.2	-0.5	0.1	-1.5	0.1	-1.0	-1.3	0.2	-1.3	-1.3
Hair/balding pattern: Pattern 4	0.4	1.0	3.4	-1.8	-0.9	0.0	-1.4	-0.7	0.4	-1.2	-0.7	-0.7
Birth weight of first child	0.3	0.5	2.1	-0.0	0.1	-1.5	0.2	-0.3	-0.4	0.7	-1.0	-0.9
Peak expiratory flow (PEF)	2.4	5.7	13.5	2.4	1.0	0.3	2.5	3.7	1.3	2.9	1.5	3.5
Pulse wave reflection index	0.7	0.8	3.0	0.3	-0.6	-0.4	0.5	1.1	1.7	-0.5	0.2	1.4
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.7	0.2	-0.4	-0.4	0.3	0.2	-0.2	0.8	-0.7	-0.4
Loud music exposure frequency	0.4	0.5	1.1	0.5	0.6	0.8	-1.0	-0.8	-0.8	-0.7	0.1	-0.6
Qualifications: O levels/GCSEs or equivalent	3.5	5.6	12.3	2.2	0.9	-0.5	2.6	3.5	2.5	2.7	1.7	3.0
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.6	-0.6	-0.1	0.2	-0.5	-1.5	-1.1	-0.9	-0.4	-1.6
Blood clot in the leg (DVT)	0.9	1.1	3.0	-0.8	-1.0	-1.7	0.2	1.3	1.7	-0.6	0.2	0.8
Medication: Paracetamol	0.4	0.7	2.3	-0.0	-0.8	-0.2	1.1	0.3	-0.4	1.5	-1.2	-0.5
Headache pain in last month	0.6	1.0	6.4	1.2	0.1	-2.5	0.1	0.3	-0.9	0.5	0.3	0.0
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	2.5	1.6	0.4	-0.7	0.7	1.5	1.3	1.3	-0.1	1.0
Glaucoma (self-reported)	0.2	0.2	0.6	-0.5	-0.4	-0.5	0.1	0.3	0.2	-0.2	0.5	0.8
Gout (self-reported)	0.7	0.9	3.8	-1.0	-1.5	-1.9	0.5	-0.1	-0.2	-0.1	-0.7	-0.3
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	6.6	0.3	-0.0	-0.9	0.3	0.8	2.6	0.1	1.6	0.9
Medication: Amlodipine	2.0	2.8	5.8	-1.4	-0.9	-0.8	-2.0	-2.0	-1.6	-2.1	-0.9	-2.4
Medication: Ventolin 100micrograms inhaler	1.7	2.2	4.9	-1.6	-1.4	1.3	-0.4	-1.9	-1.7	-0.7	-1.2	-2.2
Birth weight	0.4	1.0	2.6	1.6	1.4	0.6	0.6	0.7	-0.5	1.5	-0.5	0.4
Chronic bronchitis/emphysema (mother)	2.5	2.9	6.2	-1.7	-2.5	0.9	-2.2	-1.3	-1.3	-1.5	-1.8	-1.8
High blood pressure (siblings)	1.3	1.8	4.2	-1.5	-1.1	0.3	-0.9	-1.9	-0.4	-1.8	-0.6	-2.1
Forced vital capacity (FVC), Best measure	0.7	2.7	8.6	-0.1	-0.9	-0.8	1.3	2.9	2.0	0.6	0.8	2.7
Body fat percentage	1.0	3.9	12.9	1.9	1.8	-0.5	3.0	2.0	0.2	3.6	-0.2	1.4
Leg fat percentage (right)	1.4	5.2	13.8	2.3	2.2	-0.2	3.4	2.5	0.9	3.7	0.1	2.0
Arm fat-free mass (right)	0.7	3.4	10.3	0.7	-0.4	-0.8	3.2	3.0	0.6	2.5	-0.3	2.0
Exposure to tobacco smoke outside home	0.3	0.4	1.5	-0.0	-0.1	0.8	0.2	0.1	-1.2	1.1	-0.3	-0.5
Comparative body size at age 10	0.3	0.9	1.4	1.0	1.1	0.4	0.7	0.9	1.0	0.7	1.1	1.2
Number of full brothers	0.8	1.1	3.1	0.7	0.2	-0.9	0.2	-1.1	-1.8	0.7	-0.7	-1.7
Worry too long after embarrassment	0.9	1.5	4.1	-0.1	0.0	0.6	-1.5	-2.0	-1.0	-1.3	-1.0	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	1.0	1.7	0.5	1.3	1.2	1.2	-0.5	-1.0	1.2	-0.6	-1.0
Wheeze or whistling in the chest in last year	0.9	1.7	4.5	-0.5	-1.0	2.1	-0.8	-1.5	-1.9	-0.6	0.0	-1.5
Number of children fathered	2.6	2.9	5.4	1.3	1.0	-0.1	2.3	2.2	1.8	2.3	1.0	1.9
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	1.4	-0.7	-1.1	0.0	-0.9	-0.9	-0.0	-0.6	-0.6	-1.2
Age at first live birth	0.8	1.3	2.7	0.5	1.6	0.8	0.8	1.6	1.3	0.7	1.2	1.3
Pulse wave peak to peak time	0.2	0.2	0.6	0.3	0.4	0.7	-0.3	0.1	0.2	-0.3	0.8	0.3
Health satisfaction	3.9	5.1	12.5	-1.8	-0.3	0.3	-1.8	-3.2	-3.0	-2.3	-1.5	-3.5
Shortness of breath walking on level ground	0.5	0.6	2.1	-0.4	-0.1	-1.4	-0.0	-0.9	-0.6	-0.3	-0.6	-1.3
Qualifications: College or University degree	0.8	2.6	4.4	1.5	1.7	1.6	1.2	1.4	2.1	0.7	2.0	1.8
Eye problems/disorders: None of the above	1.3	1.5	4.8	2.2	1.3	0.4	1.0	1.0	0.0	1.3	1.1	1.2
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.3	0.3	0.6	-0.4	0.5	-0.3	0.4	0.4	0.5	-0.5
Emphysema/chronic bronchitis	0.8	0.8	2.9	0.0	-0.9	1.7	-0.3	-1.1	-0.8	-0.1	-0.5	-1.3
Medication for pain relief, constipation, heartburn	0.6	1.0	2.2	1.3	1.0	0.5	-0.5	0.6	1.5	-0.6	1.2	1.0
Neck or shoulder pain in last month	0.6	0.8	1.5	-1.1	-0.7	-1.2	-0.5	-0.9	-1.1	-0.4	0.3	-1.1
Medication: Blood pressure	0.8	1.5	2.7	-1.5	-0.7	0.9	-1.2	-1.6	-1.4	-1.4	0.3	-1.4
Angina (self-reported)	1.1	1.5	2.8	-1.7	-0.9	0.8	-1.2	-1.1	-0.1	-1.6	-1.3	-1.4
Migraine (self-reported)	1.7	2.1	5.7	2.4	1.1	-0.3	1.0	1.4	1.6	1.2	1.3	1.9
Medication: Ibuprofen	1.6	1.9	3.2	1.1	0.4	-1.8	1.4	1.7	0.4	1.6	1.5	1.6
Medication: Allopurinol	0.5	0.6	2.0	-0.8	-1.0	-1.4	0.1	-0.6	-1.0	-0.2	-0.2	-0.7
Medication: Omeprazole	2.1	2.5	4.8	-2.1	-2.2	2.1	-1.4	-1.1	-0.7	-1.3	-1.6	-1.0
Medication: Seretide 50 evohaler	0.6	0.7	1.3	-0.6	-0.9	-1.1	-1.1	-0.6	0.7	-1.2	-0.3	-0.8
Mean time to correctly identify matches	0.5	0.9	5.5	0.2	0.8	2.4	-0.3	0.1	-0.5	1.1	-0.7	0.1
Heart disease (mother)	0.2	0.3	0.7	-0.6	0.6	0.0	-0.6	-0.5	-0.6	-0.9	0.3	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	2.4	-0.4	-0.3	0.0	1.1	1.5	0.9	0.9	0.8	1.6
Whole body fat mass	1.0	4.1	13.9	1.8	1.2	-0.8	3.4	2.2	0.0	3.7	-0.4	1.3
Leg fat mass (right)	1.6	6.3	18.0	2.3	1.8	-0.4	4.0	3.0	0.7	4.2	0.1	2.1
Arm predicted mass (right)	0.8	3.9	11.2	0.8	-0.5	-1.1	3.3	3.0	0.6	2.8	-0.1	2.1
Pulse rate, automated reading	0.6	2.0	6.5	-0.9	-0.2	2.5	-0.3	-1.8	-0.5	-0.5	-1.6	-2.1
Alcohol intake frequency.	0.5	1.1	2.3	-0.2	-1.5	-0.5	1.5	-0.7	-1.1	1.4	-1.0	-0.7
Comparative height size at age 10	0.1	0.4	1.2	0.4	-0.1	-1.1	0.7	0.3	-0.9	0.8	-0.5	0.4
Number of full sisters	0.7	0.9	2.6	-0.6	-1.0	0.3	-0.9	-1.3	-0.4	-0.9	-0.5	-1.6
Suffer from ‘nerves’	0.4	0.7	1.6	0.4	1.3	0.3	-0.4	-0.9	-1.1	0.5	-1.1	-0.8
Overall health rating	1.9	4.0	12.3	-1.4	0.1	-0.0	-1.3	-2.8	-3.5	-1.5	-0.8	-3.0
Chest pain or discomfort	0.2	0.2	0.9	0.1	0.2	0.4	0.9	0.2	1.0	0.3	0.3	0.1
Had major operations	1.2	1.4	5.1	-1.0	0.0	0.4	-2.2	-1.0	-0.7	-1.9	0.1	-0.8
Age at last live birth	0.1	0.2	0.6	0.1	0.2	-0.8	-0.6	0.5	-0.3	-0.5	-0.2	0.6
Family relationship satisfaction	2.4	3.0	7.8	-1.7	-1.6	-1.7	-1.5	-1.6	0.3	-2.8	-1.6	-1.8
Leg pain on walking	1.2	1.4	2.8	-0.4	0.9	-0.6	-1.7	-1.6	-1.4	-1.2	0.6	-1.7
Qualifications: NVQ or HND or HNC or equivalent	3.8	4.6	10.9	1.9	3.3	1.4	1.9	2.4	-0.4	2.6	1.9	2.2
Commuting to job workplace: Car/motor vehicle	2.3	2.6	5.3	1.6	1.0	-0.3	1.0	2.3	1.1	1.6	2.1	2.3
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	5.8	-2.4	-1.3	2.2	-1.5	-1.6	-0.4	-2.2	-0.7	-1.1
Medication: Aspirin	1.0	1.4	2.6	-1.4	-0.1	1.6	-0.4	-1.6	-1.4	-0.8	-0.3	-1.6
Supplements: Vitamin C	0.1	0.1	0.4	-0.1	-0.4	0.2	-0.1	-0.5	-0.3	-0.3	-0.2	-0.6
Knee pain experienced in last month	0.8	1.3	2.8	-0.7	-1.6	1.5	-1.6	-0.4	-0.2	-1.7	-0.2	-0.9
Hypertension (Self-reported)	0.2	0.5	1.5	0.2	1.2	1.0	-0.3	-0.3	0.4	-0.3	1.2	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	3.1	-1.2	-0.9	1.8	-0.7	-1.1	-0.9	-1.1	-1.4	-0.8
Illnesses of father: Heart disease	1.6	2.2	6.1	-0.1	0.5	2.5	-0.7	-2.3	-1.6	0.1	-1.4	-1.9
Illnesses of siblings: Diabetes	2.0	2.4	5.0	-2.0	-2.2	-0.7	-1.3	-1.3	-1.1	-2.2	-0.8	-1.3
Smoking status: Previous	1.3	2.0	11.9	-1.6	-3.5	-1.3	0.3	1.1	0.3	-0.4	-0.2	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	3.5	0.4	0.6	0.2	1.6	1.0	0.1	1.9	1.0	0.8
Whole body fat-free mass	0.7	3.8	12.0	1.1	-0.4	-0.9	3.5	2.9	0.7	2.8	-0.2	1.8
Leg fat-free mass (right)	0.8	4.0	13.0	1.1	-0.3	-1.1	3.6	2.8	0.5	3.1	-0.0	1.6
Arm fat percentage (left)	1.2	4.6	16.0	2.4	2.0	-0.5	3.3	2.0	-0.0	4.0	0.1	1.2
Average weekly red wine intake	1.1	1.7	10.7	0.1	0.7	3.3	1.0	0.0	-0.4	1.6	-0.3	-0.0
Handedness (chirality/laterality): Left-handed	1.1	1.4	3.2	0.0	-0.9	-1.3	-0.8	-1.8	-1.8	-1.2	0.2	-1.3
Mood swings	0.9	1.5	10.7	-0.2	0.7	3.3	0.6	0.3	-0.9	1.0	-0.6	-0.1
Loneliness, isolation	0.4	0.6	2.5	-0.4	0.6	-0.2	-0.8	-0.9	-1.6	-0.4	-0.3	-0.7
Long-standing illness, disability or infirmity	0.5	0.7	2.7	-0.5	0.5	0.3	-0.2	-1.1	-1.6	-0.1	-0.2	-1.4
Ever had bowel cancer screening	4.6	5.4	10.2	-2.3	-1.6	0.9	-2.6	-3.2	-2.3	-2.6	-1.1	-3.1
Diabetes diagnosed by doctor	0.6	0.9	4.2	-0.9	-0.4	1.2	2.1	0.2	-0.3	1.0	-0.5	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	2.0	1.1	1.4	1.2	-0.1	-1.2	-1.1	-0.2	1.3	-1.1
Friendships satisfaction	1.3	1.5	2.5	-1.0	-1.3	-1.6	-1.4	-1.1	-1.0	-1.2	-1.1	-1.3
Qualifications: nursing, teaching	0.2	0.3	0.8	-0.4	-0.1	0.3	0.3	0.9	0.5	0.2	-0.7	0.7
Commuting to job workplace: Walk	4.1	4.5	8.1	-2.5	-2.0	-0.7	-2.0	-2.8	-1.8	-2.4	-1.1	-2.6
Eye problems/disorders: Cataract	2.4	2.8	4.7	-2.2	-1.2	-0.4	-1.7	-1.8	-0.6	-1.8	-2.2	-2.0
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.7	-0.5	-0.0	-0.1	-1.0	-1.3	-1.6	-0.8	-1.0	-1.4
Medication for cholesterol	0.2	0.3	1.7	-0.2	-1.3	-0.6	0.0	-0.0	-0.5	0.0	0.2	-0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.9	0.1	0.6	-0.1	-0.5	-0.1	-0.5	-0.2	1.0	-0.3
Back pain experienced in last month	1.1	1.5	4.0	-1.3	-1.4	-0.8	-1.0	-1.4	-0.9	-1.4	-0.3	-2.0
Mineral and other dietary supplements	0.5	0.7	3.9	-0.4	0.2	-2.0	-0.2	0.3	0.3	-0.9	-0.0	1.0
Breast cancer (self-reported)	0.3	0.4	1.2	-0.3	-1.0	0.8	-0.5	-0.2	0.2	0.0	-1.1	-0.1
Asthma (self-reported)	0.2	0.4	2.6	-0.1	-0.4	1.6	0.4	0.1	0.8	0.1	0.2	-0.1
Osteoporosis (self-reported)	3.9	4.8	10.7	-1.7	-0.9	2.1	-2.0	-3.3	-2.0	-1.8	-1.8	-3.2
Osteoarthritis (self-reported)	0.7	0.9	2.3	0.2	1.3	-0.6	-0.5	-1.5	-0.6	-1.0	0.2	-1.3
Medication: Aspirin	0.7	0.9	1.9	-1.1	0.2	1.4	-0.5	-1.3	-1.2	-0.6	-0.0	-1.2
Medication: Gliclazide	0.2	0.2	0.4	-0.3	-0.4	0.6	0.6	-0.2	0.3	0.2	0.6	-0.6
Illnesses of father: None of the above (group 1)	0.8	1.0	2.8	-0.7	-1.4	-0.5	1.7	0.7	0.9	1.2	0.5	0.6
Smoking status: Current	0.0	0.1	0.2	-0.3	0.4	0.2	0.1	0.3	-0.1	-0.4	0.1	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	3.1	0.2	-0.2	0.8	0.1	1.4	1.1	-0.3	0.5	1.8
Whole body water mass	0.6	3.5	11.4	1.0	-0.5	-1.0	3.4	2.8	0.6	2.7	-0.3	1.7
Leg predicted mass (right)	0.8	4.3	13.8	1.2	-0.3	-1.1	3.7	2.9	0.6	3.2	0.1	1.7
Arm fat mass (left)	1.1	4.7	15.6	2.0	1.1	-0.9	3.7	2.3	-0.0	4.0	-0.2	1.3
Number of self-reported non-cancer illnesses	0.3	0.5	3.1	-0.7	-0.2	1.8	0.5	-0.2	0.6	0.1	-0.5	-0.2
Average weekly champagne plus white wine intake	0.6	0.9	5.4	-0.7	0.0	-2.3	-0.9	-0.3	-0.6	-0.7	0.1	0.0
Miserableness	0.6	1.0	2.1	0.9	1.1	1.4	0.9	0.0	-1.2	1.4	0.2	-0.3
Guilty feelings	1.7	2.6	5.9	-1.7	-1.4	-0.4	-0.6	-2.1	-1.5	-0.8	-2.2	-2.4
Wears glasses or contact lenses	0.6	0.7	2.0	-0.4	-0.3	1.2	0.4	-1.0	-0.5	0.9	-0.6	-1.4
Ever taken oral contraceptive pill	3.4	3.8	7.0	1.7	2.3	0.7	2.1	2.6	-0.0	2.7	1.4	2.2
Hearing aid user	0.7	0.8	1.9	-1.4	-1.3	-0.5	0.8	-0.5	-0.9	-0.1	-0.6	-1.2
Mother’s age at death	0.8	1.1	2.7	-1.4	-0.5	-0.8	-1.4	-0.9	0.0	-1.6	-0.8	-0.7
Financial situation satisfaction	1.5	1.9	3.3	-1.1	-1.6	-0.9	-1.4	-1.1	-1.5	-1.0	-1.8	-1.6
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.7	-0.7	-0.6	1.3	-0.3	-0.3	-0.7	0.7	-0.8	-1.0
Commuting to job workplace: Public transport	0.5	0.6	2.5	0.2	-0.2	0.9	1.6	-0.6	0.5	0.5	-1.0	-0.6
Eye problems/disorders: Glaucoma	0.2	0.2	0.6	-0.8	0.2	-0.8	0.1	0.0	0.1	-0.2	0.4	0.5
Medication: Blood pressure	0.1	0.3	0.7	-0.3	0.5	0.9	-0.4	-0.5	0.1	-0.8	-0.6	-0.1
Pain type(s) experienced in last month: Hip pain	1.5	1.8	3.6	-1.9	-1.2	-0.5	-0.8	-1.5	-0.9	-0.7	-1.9	-1.9
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.6	0.0	-0.1	1.3	-0.4	-0.1	0.1	0.0	-0.3	-0.7
High cholesterol (Self-reported)	0.4	0.7	1.3	-0.8	0.8	0.6	-1.0	-1.1	-0.3	-1.2	-0.5	-0.7
Medication: Bendroflumethiazide	0.4	0.6	1.1	-0.9	-1.1	0.8	-0.4	-0.9	0.2	-1.0	-0.8	-0.3
Medication: Paracetamol	0.3	0.5	1.5	-0.2	-1.1	-0.0	0.4	-0.2	-0.2	1.0	-1.2	-0.9
Medication: Lisinopril	0.3	0.4	2.6	-0.5	0.4	1.6	0.2	-0.5	-0.2	-0.5	-0.1	-0.1
Medication: Atorvastatin	0.9	1.1	2.0	-1.2	-0.3	0.9	-1.2	-1.4	-1.4	-1.0	-0.4	-1.2
Illnesses of father: High blood pressure	2.1	2.7	6.6	1.2	2.6	1.6	-0.9	-2.2	-2.1	-0.4	0.4	-1.7
Alcohol drinker status: Never	0.6	0.7	1.7	-0.6	-0.7	1.3	0.1	-0.9	0.0	0.7	-1.3	-0.8
Ever smoked	0.8	1.5	4.4	-1.4	-2.1	-1.1	0.6	1.7	0.7	-0.8	0.2	1.2
Basal metabolic rate	0.8	4.3	13.7	1.3	-0.2	-1.1	3.7	3.0	0.6	3.1	-0.2	1.8
Leg fat percentage (left)	1.4	5.0	14.8	2.2	2.1	0.0	3.3	2.5	0.7	3.8	0.1	1.9
Arm fat-free mass (left)	0.7	3.8	11.6	1.0	-0.6	-1.2	3.4	2.9	0.6	2.6	-0.5	1.9
Number of operations (self-reported)	0.9	1.4	3.2	-0.7	0.5	1.8	-1.6	-1.5	-0.5	-1.4	-0.1	-1.3
Average weekly beer plus cider intake	0.4	0.6	2.1	1.0	0.7	0.2	1.4	0.6	0.6	0.7	0.8	0.4
Irritability	1.2	2.0	10.3	-0.6	0.5	3.2	1.2	1.7	0.8	0.7	-0.3	1.3
Risk taking	1.3	1.8	6.1	1.2	0.6	-1.0	-0.2	1.7	1.6	-0.2	2.5	1.5
Ever had prostate specific antigen (PSA) test	0.3	0.3	2.1	-0.1	-0.4	-1.5	0.3	0.1	-0.1	0.3	-0.6	-0.1
Fractured/broken bones in last 5 years	0.6	0.7	1.5	-1.1	-1.0	-1.2	-1.0	-0.7	-0.6	-0.8	0.1	-0.7
Age started oral contraceptive pill	7.2	9.0	12.4	-3.5	-2.4	2.4	-3.1	-3.3	-2.2	-3.1	-3.4	-3.3
Diastolic blood pressure, automated reading	0.5	1.5	5.6	1.0	1.6	2.4	-0.0	1.0	0.7	1.0	1.0	0.9
Ever depressed for a whole week	0.6	0.7	1.4	-0.9	-0.7	-0.0	-0.6	-1.1	-1.1	-0.7	-0.7	-1.2
Unable to work because of sickness or disability	1.8	2.3	6.2	-0.7	-1.0	0.0	-1.3	-2.0	-2.5	-0.8	-1.2	-2.3
Commuting to job workplace: Cycle	0.2	0.2	0.7	-0.5	-0.2	0.0	0.0	-0.8	-0.7	-0.1	0.5	-0.5
Myopia	0.7	1.1	2.0	0.8	0.8	1.2	-1.2	-1.2	-1.4	-0.9	0.5	-1.0
Vascular/heart problems diagnosed by doctor	0.2	0.6	1.5	0.1	-0.7	-1.2	1.2	0.6	0.4	0.8	-1.1	0.1
Cholesterol lowering medication	0.8	1.2	2.5	-1.1	0.0	0.5	-1.4	-1.1	-1.0	-1.6	-1.0	-1.2
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	6.6	-1.9	-2.0	2.6	-1.2	-0.4	-0.4	-1.3	-1.4	-0.5
Pain experienced in last month	2.6	4.3	7.8	2.2	2.2	0.4	2.6	2.1	1.8	2.8	1.1	2.3
Supplements: Calcium	1.0	1.1	3.9	0.2	0.4	0.9	0.7	-1.9	-0.8	0.4	-0.7	-2.0
Basal cell carcinoma (self-reported)	1.1	1.3	2.7	0.5	1.0	-0.6	1.4	1.6	1.6	1.1	0.6	1.1
Heart attack/myocardial infarction (self-reported)	0.8	1.1	2.2	-0.9	-0.6	0.4	-1.5	-1.0	-1.4	-1.0	-1.2	-0.9
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	4.4	-0.5	-0.5	-1.7	0.2	1.6	2.1	-0.6	0.6	1.1
Heart disease (siblings)	0.3	0.4	1.0	-0.3	0.4	-0.4	-0.7	-0.8	-1.0	-0.1	0.2	-1.0
Alcohol drinker status: Previous	0.5	0.6	1.6	-0.2	-1.0	0.4	0.5	-0.5	-1.3	0.5	-0.8	-0.9
Pack years of smoking	1.6	2.3	3.8	-1.9	-1.6	1.3	-1.4	-1.5	-1.3	-1.7	-1.6	-1.2
Impedance of whole body	0.1	0.7	2.4	0.1	1.0	0.7	-1.6	-1.1	-0.1	-0.9	0.3	-0.2
Leg fat mass (left)	1.6	6.2	18.7	2.3	1.8	-0.3	3.9	3.0	0.5	4.3	0.1	1.9
Arm predicted mass (left)	0.7	3.6	10.8	0.6	-0.9	-1.4	3.3	2.9	0.6	2.3	-0.8	1.9