Hub : Genes

SCRN3

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.4160 0.0520 0.0e+00 0.242 0.221 0.235 0.265 0.245 3.6e-29 1.8e-26 3.5e-28 3.1e-32 1.4e-29
2 GTEx Adrenal Gland 0.4123 0.1025 8.5e-05 0.111 NA 0.082 NA 0.096 8.6e-05 NA 6.9e-04 NA 2.5e-04
3 GTEx Artery Tibial 0.1456 0.0564 6.5e-03 0.069 NA 0.078 NA 0.084 4.4e-06 NA 9.7e-07 NA 4.0e-07
4 GTEx Brain Frontal Cortex BA9 0.2570 0.1109 6.3e-03 -0.008 NA -0.010 NA -0.006 6.1e-01 NA 7.5e-01 NA 5.1e-01
5 GTEx Esophagus Gastroesophageal Junction 0.2120 0.0790 3.3e-03 -0.006 NA -0.004 NA -0.006 6.2e-01 NA 4.7e-01 NA 6.1e-01
6 GTEx Esophagus Muscularis 0.1350 0.0550 2.0e-03 0.120 NA 0.061 NA 0.089 9.9e-08 NA 1.4e-04 NA 4.4e-06
7 GTEx Skin Not Sun Exposed Suprapubic 0.1370 0.0530 4.0e-03 0.005 NA 0.011 NA 0.009 1.6e-01 NA 7.4e-02 NA 9.3e-02
8 NTR Blood 0.0134 0.0064 7.9e-03 0.001 0.004 0.000 0.004 0.000 1.2e-01 1.1e-02 2.7e-01 1.3e-02 2.8e-01
9 ROSMAP Brain Pre-frontal Cortex 0.0904 0.0249 1.8e-09 0.113 0.082 0.108 0.107 0.109 2.3e-14 1.0e-10 1.0e-13 1.2e-13 7.8e-14
10 TCGA Breast Invasive Carcinoma 0.0115 0.0078 8.3e-03 0.005 0.006 -0.001 NA 0.000 3.1e-02 1.8e-02 5.9e-01 NA 2.8e-01
11 TCGA Glioblastoma Multiforme 0.2360 0.1170 2.4e-03 0.150 0.078 0.075 NA 0.131 2.7e-05 2.2e-03 2.7e-03 NA 8.8e-05
12 TCGA Kidney Renal Clear Cell Carcinoma 0.0688 0.0387 5.9e-05 0.042 0.048 0.046 NA 0.040 1.5e-05 4.0e-06 5.8e-06 NA 2.3e-05
13 TCGA Brain Lower Grade Glioma 0.0379 0.0245 1.9e-03 0.007 0.025 0.013 NA 0.015 4.8e-02 6.7e-04 1.2e-02 NA 6.1e-03
14 TCGA Stomach Adenocarcinoma 0.0750 0.0430 2.3e-04 0.032 0.052 0.029 NA 0.024 2.2e-03 1.1e-04 3.3e-03 NA 6.9e-03
15 TCGA Testicular Germ Cell Tumors 0.2010 0.0900 3.8e-06 0.108 0.130 0.144 NA 0.124 1.2e-04 2.5e-05 8.8e-06 NA 3.9e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 1.0 1.5 6.5 -0.2 -0.5 -1.7 -1.6 -0.1 -0.7 -2.5 0.6 1.0 -1.3 0.8 -1.5 -0.1 -1.8 0.9
Bipolar Disorder or Schizophrenia 2.1 5.0 14.4 -2.3 -1.9 -3.8 -2.5 1.0 -0.9 -3.7 2.2 1.4 -2.0 1.3 -2.7 -1.0 -2.9 1.4
Depressed Affect (Nagel 2018) 0.3 0.7 2.8 -1.3 -0.3 -1.7 -0.6 0.7 0.1 -0.5 1.2 -0.2 -0.6 1.1 -0.6 -0.5 -0.8 0.3
Depression (Nagel 2018) 2.6 3.8 8.4 -1.9 -1.0 -2.3 -1.8 0.3 -1.4 0.5 2.6 1.4 -2.3 2.9 -2.7 0.4 -2.7 2.2
Intelligence (Savage-Jansen 2018) 0.1 0.4 1.5 -0.5 0.1 -0.9 -1.2 -1.1 -0.3 0.6 -0.4 -0.1 -0.1 -0.3 -0.3 -0.6 -0.0 -0.7
Neuroticism (Nagel 2018) 0.4 0.8 1.8 -1.0 0.7 -0.6 1.3 1.0 1.3 -1.2 1.1 -1.2 0.3 1.3 0.7 -0.6 0.3 -0.0
Schizophrenia (2018) 1.9 4.0 12.6 -2.8 -2.0 -3.5 -1.9 1.2 -0.6 -2.7 2.3 0.9 -1.6 1.1 -2.2 -1.2 -2.2 1.1
Schizophrenia vs Biploar Disorder 0.4 0.5 1.6 -0.9 0.6 -0.2 1.1 1.3 1.0 0.0 0.3 -0.8 0.5 0.7 0.3 -0.8 0.4 0.1
Worry (Nagel 2018) 0.3 0.6 1.7 -0.6 0.9 -0.3 1.3 1.1 1.1 -0.6 0.8 -0.7 0.5 0.0 0.9 -0.9 0.5 -0.2
Alzheimer’s Disease (in mother) 2.2 2.5 7.5 -1.1 2.7 -0.7 1.5 0.8 2.1 -2.2 -1.0 -2.2 1.1 0.2 1.6 -1.5 1.6 -1.5
Alzheimer’s Disease (in father) 0.4 0.4 1.9 -1.0 0.7 -1.4 -0.5 -0.6 -0.2 0.3 1.1 -0.2 -0.8 0.1 -0.5 -0.2 -0.4 -0.1
Alzheimer’s Disease (including proxy) 0.9 1.3 4.6 -1.6 2.2 -1.6 0.7 0.6 1.3 -1.3 -0.2 -1.4 0.2 -0.1 0.6 -1.1 0.7 -1.2
Crohns Disease (2017) 0.2 0.4 1.7 -0.3 0.6 -0.4 -0.1 0.0 -0.1 -1.3 -0.8 0.1 -0.7 1.1 -0.3 0.5 -0.6 0.4
Irritable Bowel Disease (IBD) 0.1 0.2 0.8 -0.4 -0.2 -0.6 -0.9 0.5 -0.4 -0.0 -0.8 0.2 -0.6 0.2 -0.4 0.2 -0.5 0.1
Ulcerative Colitis (UC) 0.2 0.4 1.3 -0.3 -0.7 -0.7 -1.1 0.6 -0.4 1.1 -0.8 0.1 -0.2 -0.7 -0.3 -0.3 -0.2 -0.4
Major Depression (MDD) 0.8 0.9 8.7 -0.4 0.8 -0.6 -0.3 3.0 0.7 0.3 -0.3 -0.5 0.7 -0.5 0.3 -1.3 0.2 -0.7
Reaction Time 5.6 10.7 26.1 2.7 -4.7 2.4 -2.9 -0.2 -4.2 1.0 5.1 4.7 -2.5 0.0 -2.8 4.5 -2.8 2.9
Verbal and Numeric Reasoning (VNR) 0.2 0.4 1.8 0.2 -0.7 0.2 -0.1 0.1 0.5 1.4 -0.5 -0.2 0.8 -0.9 0.8 -0.5 0.8 -0.7
Breast Cancer 0.6 1.4 6.7 -0.4 -0.7 -1.1 -1.2 -2.6 -0.7 -1.2 0.6 0.9 -1.2 1.1 -1.3 0.1 -1.2 1.3
Ovarian Cancer 2.0 2.6 6.7 -0.2 -2.6 -0.6 -2.1 -2.1 -1.9 0.6 1.3 1.6 -1.8 1.2 -1.9 1.3 -1.7 1.4
Prostate Cancer 0.6 0.8 2.9 0.4 0.4 -0.7 -1.4 0.1 -0.6 -1.7 1.1 1.1 -0.7 0.1 -1.3 -0.2 -1.3 0.5
Age at First Birth 0.1 0.2 0.6 -0.0 0.1 -0.0 0.1 0.1 0.7 -0.8 0.7 -0.3 0.3 0.5 0.1 -0.5 -0.1 0.3
Bipolar Disorder (2011) 1.1 1.1 4.0 -0.2 -1.0 -1.9 -1.0 -0.2 0.3 -1.6 0.3 0.8 0.1 -1.4 -0.7 -2.0 -0.9 -0.3
Body Mass Index (BMI) (2010) 0.6 0.9 2.5 0.6 -1.6 0.3 -1.2 1.2 -0.8 0.4 1.2 1.2 -0.5 -0.1 -0.8 0.5 -1.0 0.9
Coronary Artery Disease (CAD) 0.7 0.8 2.3 1.3 0.0 1.4 0.5 -0.5 -0.7 1.5 0.4 1.1 -0.4 -0.1 -0.4 1.5 -0.7 0.8
Crohns Disease (2012) 0.4 0.7 3.1 0.6 1.3 0.3 0.3 0.5 0.2 -0.9 -1.8 -0.1 0.6 -1.3 0.6 -0.1 0.5 -1.1
Mean Putamen Volume 0.8 1.0 4.4 2.0 0.1 2.1 1.0 -1.0 0.1 0.9 -0.6 0.5 0.9 -0.5 0.7 1.0 0.3 -0.1
Fasting Glucose 1.1 1.3 6.2 1.5 0.1 1.7 0.9 2.5 0.9 0.4 -0.1 -0.6 1.2 -0.6 1.2 0.2 1.2 -0.8
HbA1C 3.8 4.2 8.4 -1.5 -1.5 -1.4 -2.2 -1.3 -2.6 -0.3 2.2 1.8 -2.9 2.2 -2.7 1.5 -2.5 2.4
HDL Cholesterol 0.5 0.8 3.7 -0.7 -0.5 -0.4 0.3 1.6 0.6 -1.9 -1.2 -0.8 0.5 -0.7 0.6 -1.0 0.6 -0.7
LDL Cholesterol 0.7 1.1 3.3 0.7 1.6 0.9 1.2 1.1 0.7 1.8 -1.1 -1.3 1.0 -0.0 0.9 0.1 1.2 -0.8
Lupus 0.4 0.6 1.5 0.2 -0.2 0.5 0.5 -0.2 0.8 0.7 -0.7 -0.9 0.7 -1.2 1.1 -0.2 0.9 -1.1
Neuroticism (2016) 0.6 0.9 2.3 -0.9 1.5 -0.9 1.4 -1.2 1.3 -1.5 -0.1 -0.3 -0.4 1.0 0.1 -0.6 -0.3 0.6
Primary Biliary Cirrhosis 0.8 1.2 6.7 1.5 -0.8 2.0 0.4 2.6 0.1 1.2 0.0 0.4 0.4 -0.5 0.7 0.9 0.4 -0.0
Rheumatoid Arthritis 0.1 0.1 0.2 -0.0 0.1 0.1 -0.1 -0.4 0.0 0.1 -0.1 0.4 -0.5 -0.3 -0.2 0.0 -0.5 0.3
Schizophrenia (2014) 1.5 3.2 12.1 -2.9 -0.9 -3.5 -0.9 1.3 0.1 -2.6 1.6 0.3 -1.5 1.6 -1.8 -1.3 -1.9 1.2
Triglycerides 0.6 1.0 4.0 1.5 0.4 1.1 -0.7 -0.3 -1.0 2.0 1.5 1.0 -0.2 0.3 -0.5 1.4 -0.3 0.3
Type 2 Diabetes (T2D) (2012) 0.4 0.5 3.6 -0.3 0.3 -0.4 -0.6 0.4 -0.2 0.0 -0.2 -0.1 0.7 -1.9 0.1 -1.1 0.4 -1.1
Ulcerative Colitis 0.4 0.5 2.7 0.9 -0.3 1.1 -0.3 1.2 0.1 1.6 0.1 0.3 0.6 -1.0 0.2 0.1 0.1 -0.3
Blood Eosinophil Count 0.3 2.5 12.5 1.4 0.8 -0.5 -1.1 -3.5 -1.4 -2.0 -0.6 2.1 -1.1 -0.5 -1.7 0.4 -1.9 1.3
Blood Platelet Count 0.2 2.4 7.6 -0.1 -1.6 -0.7 -2.8 -0.2 -2.0 2.6 2.2 1.6 -1.3 -1.7 -1.2 0.7 -1.0 -0.2
Blood Red Count 0.2 1.7 8.5 -0.8 -2.0 0.7 2.0 2.9 0.9 1.1 1.4 -0.8 0.8 -0.1 1.1 -0.1 0.8 -0.5
Blood White Count 0.2 1.7 5.8 -1.8 0.2 -2.4 -1.8 -1.3 -0.6 -1.6 0.7 -0.3 -1.1 1.0 -1.6 -0.9 -1.3 0.6
Heel T-Score 0.6 4.6 12.4 -0.8 -3.1 -2.2 -3.0 -3.5 -2.4 -0.8 1.6 1.4 -2.3 1.6 -2.5 0.7 -2.0 1.5
BMI 1.0 5.6 13.2 -0.3 -2.8 -1.5 -3.6 2.0 -2.4 0.6 3.1 3.3 -1.8 -0.2 -3.2 0.6 -3.6 1.5
Height 0.6 12.2 21.8 -1.4 1.7 -1.2 3.9 3.9 4.0 -1.9 -3.6 -4.3 3.8 -3.1 3.6 -4.7 3.9 -4.5
Waist Hip Ratio (WHR) 0.3 1.4 6.0 -0.5 1.0 0.2 0.1 1.0 0.9 2.5 -0.6 -1.1 1.7 -1.4 0.9 -0.9 1.3 -1.5
Systolic Blood Pressure 2.3 11.8 30.2 -0.2 -4.7 -1.0 -4.6 2.2 -3.6 0.1 5.5 3.6 -3.9 2.4 -3.8 3.0 -4.2 2.9
Smoking Status 0.8 1.9 4.9 -1.0 2.2 -1.8 0.1 -1.8 1.3 -0.3 -1.2 -1.8 0.7 -0.8 0.5 -2.1 1.0 -1.6
Allergy or Eczema 0.3 0.9 1.9 1.4 -1.2 0.9 -1.3 -1.0 -0.6 -0.6 0.0 1.4 -0.7 -0.1 -0.6 0.7 -1.0 1.1
Cardiovascular Disease 3.3 10.9 26.0 -0.3 -3.5 -1.3 -4.6 1.3 -3.9 0.4 5.1 4.0 -3.8 1.6 -4.1 2.5 -4.4 3.0
Hypothyroidism (self reported) 0.6 1.4 3.5 -0.5 -1.9 -0.6 -1.4 -0.8 -1.1 -0.2 1.3 1.7 -1.1 0.5 -1.5 0.2 -1.7 1.6
Respiratory disease 0.1 0.3 1.0 0.1 -0.3 -0.9 -1.0 0.4 0.8 -0.4 -0.2 -0.2 0.1 -0.1 0.0 -1.0 -0.3 -0.5
Type 2 Diabetes (T2D) (2018) 1.0 1.9 3.9 -1.1 -1.3 -1.6 -2.0 0.0 -1.9 -0.7 1.7 1.0 -1.9 0.2 -1.9 0.7 -1.8 0.5
Lung FEV1/FVC ratio 1.3 6.7 14.0 0.4 2.5 1.0 2.6 2.1 2.9 3.7 -0.9 -2.7 3.6 -2.0 3.3 -2.0 3.3 -3.0
Lung FVC 1.6 8.2 15.2 0.9 -2.6 0.2 -0.8 -3.2 -2.7 -3.3 3.0 3.1 -3.9 2.8 -2.4 3.8 -3.0 3.8
Neuroticism 0.3 0.7 2.9 -1.1 0.2 -1.1 0.1 0.8 0.5 -1.4 1.7 -0.2 -0.4 1.1 -0.2 -0.7 -0.4 0.4
Chronotype (morning person) 1.7 4.0 9.2 -1.7 1.0 0.3 2.9 2.4 1.8 0.1 -2.8 -3.0 1.8 0.0 2.4 -1.1 2.9 -1.7
Hair Pigment 0.0 0.8 2.0 -1.4 -1.1 -1.1 0.7 -1.4 0.5 -1.0 -0.1 -0.8 0.4 -0.5 0.2 -1.4 0.6 -0.7
Tanning 0.1 1.0 3.8 -1.5 0.9 -0.6 0.7 -0.7 0.8 -0.7 -1.0 -1.9 0.5 0.5 1.0 -0.3 1.4 -0.8
Hand grip strength (left) 0.9 2.3 7.9 -2.8 0.1 -0.8 2.0 -1.5 0.6 -0.0 -0.9 -2.8 -0.2 2.2 1.3 0.3 1.8 -0.5
Number of treatments/medications taken 2.5 4.6 9.5 -0.0 -3.1 -0.5 -3.1 0.0 -2.6 0.4 2.6 2.8 -2.4 0.6 -2.7 1.4 -2.8 2.2
Average weekly spirits intake 0.5 0.6 1.9 -1.4 -0.4 -0.9 -0.5 0.6 0.1 0.7 -0.5 -1.2 0.3 -0.5 0.6 -0.7 0.7 -1.2
Sensitivity / hurt feelings 0.4 0.7 2.5 -0.3 0.8 -0.2 1.6 -0.7 1.1 -1.5 0.7 -0.5 -0.1 1.3 0.5 -0.4 -0.1 0.7
Frequency of depressed mood in last 2 weeks 2.1 3.0 8.0 -2.3 0.4 -2.8 -1.7 0.1 -0.9 -0.0 2.2 0.5 -2.1 2.5 -2.1 -0.2 -2.2 1.5
Hearing difficulty/problems: Yes 0.2 0.3 0.9 0.8 0.6 0.9 0.5 -0.9 -0.1 0.7 0.2 0.5 0.2 -0.9 0.3 -0.1 -0.0 -0.0
Relative age of first facial hair 0.6 1.2 5.3 -0.6 -2.3 0.4 -0.7 -0.6 -1.4 -1.6 0.9 0.2 -0.9 1.0 -0.9 1.7 -0.2 0.7
Other serious medical condition/disability diagnosed by doctor 1.3 1.7 3.8 -0.4 -1.6 -0.1 -1.9 0.1 -1.9 0.1 0.9 1.9 -1.3 -0.5 -1.6 0.4 -1.9 1.3
Ever used hormone-replacement therapy (HRT) 1.4 1.7 5.3 -1.3 2.0 -0.2 1.3 -0.4 1.3 0.2 -2.3 -1.6 1.2 -1.0 0.8 -1.7 1.0 -1.3
Ever had hysterectomy (womb removed) 1.3 1.5 4.0 0.8 -1.9 1.5 0.6 -0.0 -1.0 -1.0 0.9 1.3 -0.9 1.2 -0.7 2.0 -1.0 1.8
Systolic blood pressure, automated reading 1.2 3.5 8.5 0.9 -2.7 -0.5 -2.9 2.4 -1.4 -0.1 2.9 2.7 -1.4 -0.3 -1.7 0.8 -2.4 1.2
Eye problems/disorders: Diabetes related eye disease 0.7 0.7 2.4 -1.1 -1.1 -1.6 -1.1 0.3 -0.2 -0.6 -0.5 0.0 -0.1 -1.4 -0.3 -1.1 -0.2 -0.7
Angina 0.7 1.0 4.9 -1.6 0.0 -0.9 -0.2 0.9 0.1 2.2 0.3 -1.0 0.3 -0.8 0.2 -0.9 0.7 -1.4
Medication for hormone replacement therapy 0.7 0.8 2.2 -1.5 -0.2 -0.4 0.1 -1.5 -0.2 1.1 -1.3 -1.0 0.5 -0.8 0.1 -0.9 0.8 -1.0
Vitamin and mineral supplements 0.4 0.6 2.1 -0.2 0.2 0.2 -0.1 -0.7 -0.4 -0.7 0.2 0.3 -0.9 1.4 -0.5 1.3 -0.8 1.1
Supplements: Zinc 0.4 0.5 2.2 -0.5 0.2 -0.4 0.3 0.4 0.2 -1.1 1.2 -0.1 -0.3 1.5 -0.3 -0.0 -0.6 1.0
Medication: Co-codamol 1.4 1.7 7.9 0.0 0.1 -1.1 -1.3 2.8 0.4 -1.5 -0.2 0.4 0.4 -2.8 0.2 -1.5 -0.1 -1.2
Medication: Metformin 1.6 2.3 4.4 -1.6 -1.2 -1.4 -1.8 0.7 -1.9 0.4 2.1 1.1 -2.1 0.6 -2.1 0.9 -2.1 0.9
Diabetes (father) 0.6 0.7 1.6 -0.4 -1.2 -1.3 -1.1 0.7 -0.3 -0.9 0.3 0.8 -1.0 0.1 -1.2 -0.7 -1.2 0.4
Diabetes (mother) 0.7 0.9 2.5 -0.2 -1.0 -0.2 -0.9 -0.2 -1.0 0.3 0.9 1.5 -0.9 -0.0 -1.6 0.1 -1.6 1.2
Severe depression (siblings) 0.2 0.2 1.9 -0.1 -0.4 -0.2 -0.4 -0.5 0.0 0.4 0.9 -0.1 -0.2 1.4 -0.2 0.2 -0.2 0.3
Pack years adult smoking proportion 0.2 0.4 1.9 -0.2 1.4 0.2 0.8 1.1 0.4 0.2 -0.9 -0.4 0.3 -0.5 0.3 -0.1 0.3 -0.3
Impedance of leg (right) 0.2 0.8 2.4 -0.1 0.3 0.4 0.8 -0.7 1.0 0.9 -0.2 -1.5 1.3 0.1 1.4 -0.3 1.5 -1.1
Leg fat-free mass (left) 0.2 1.2 7.5 -0.6 -1.3 -1.4 -1.1 2.7 -0.6 -0.3 0.7 0.9 -0.6 -0.6 -1.2 -0.7 -1.3 -0.0
Trunk fat percentage 0.7 2.7 8.8 0.6 -1.6 -0.5 -2.1 0.6 -1.3 1.4 3.0 2.5 -0.9 0.0 -2.2 0.3 -2.6 1.2
Hand grip strength (right) 0.5 1.5 6.9 -2.6 -0.1 -1.3 1.2 -1.0 0.4 -0.1 -0.6 -2.3 -0.2 1.3 0.8 -0.3 1.4 -0.8
Townsend deprivation index at recruitment 0.4 0.6 2.8 -0.6 0.5 -1.7 -1.0 -0.9 0.1 -1.1 0.3 0.2 -0.3 -0.4 -1.0 -0.7 -0.9 -0.1
Current tobacco smoking 1.0 1.7 7.4 -1.2 2.7 -1.4 0.3 -0.2 0.9 0.4 -1.5 -1.5 0.9 -1.2 0.5 -1.8 0.8 -1.7
Average weekly fortified wine intake 0.9 1.0 3.3 0.4 1.3 -0.1 0.9 -0.3 1.3 -0.3 -1.8 -1.0 1.3 -0.5 1.1 -1.3 0.9 -0.9
Maternal smoking around birth 0.5 0.8 3.2 -0.7 1.3 -0.8 -0.8 -1.6 -0.4 -0.3 -0.1 -0.3 -0.9 1.8 -0.8 0.2 -0.5 0.4
Fed-up feelings 0.2 0.3 0.9 -0.5 0.9 -0.9 0.0 0.5 0.5 0.4 0.3 -0.5 0.4 -0.3 0.2 -0.8 0.1 -0.7
Frequency of unenthusiasm / disinterest in last 2 weeks 2.6 3.5 7.5 -2.5 -0.9 -2.7 -2.6 -0.2 -1.8 -0.0 1.9 1.2 -2.4 1.7 -2.7 -0.0 -2.3 1.4
Relative age voice broke 0.6 0.9 3.7 -1.1 -1.3 -0.3 -1.9 -0.3 -1.6 -0.8 -0.8 -0.0 -0.9 0.2 -0.7 1.4 -0.2 -0.1
Taking other prescription medications 1.0 1.6 5.0 0.2 -1.6 0.4 -1.4 0.4 -1.3 0.9 2.2 1.5 -1.1 1.0 -1.5 0.8 -1.6 1.4
Age when periods started (menarche) 0.6 1.5 3.5 0.6 1.1 0.7 1.0 0.7 1.4 0.0 -1.5 -1.6 1.5 -1.0 1.5 -0.4 1.9 -1.9
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 1.3 0.3 -0.5 1.2 0.7 0.6 0.1 0.3 -0.3 -0.2 0.6 -0.4 0.6 0.4 0.9 -0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.5 8.9 -1.5 -0.1 -3.0 -0.6 -1.1 -0.4 -2.1 -0.6 -0.5 -0.5 -0.2 -0.9 -1.6 -0.4 -0.5
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 1.0 0.2 0.2 -0.6 -1.0 0.2 -0.6 -0.3 -0.1 0.8 -0.8 0.0 -0.8 0.1 -1.0 0.4
Qualifications: CSEs or equivalent 0.5 0.7 2.1 -1.0 -0.3 -1.4 -0.4 1.4 0.7 -0.2 0.8 -0.7 0.3 -0.8 0.1 -1.0 0.5 -1.0
Serious illness, injury or assault to yourself 0.6 0.7 2.4 -0.7 -1.2 -1.2 -1.0 0.6 -0.1 -0.9 0.7 0.2 -0.6 1.6 -1.0 -0.5 -0.9 0.3
High blood pressure 3.3 9.3 20.6 -1.2 -3.3 -2.1 -4.3 0.9 -3.5 0.3 4.5 3.4 -3.7 1.5 -3.9 1.7 -4.3 2.6
Hayfever, allergic rhinitis or eczema 0.4 0.8 2.4 1.2 -1.1 0.6 -1.6 -0.9 -0.6 -0.3 0.0 1.3 -0.7 -0.3 -0.6 0.6 -1.1 0.9
Multivitamins +/- minerals 0.4 0.5 2.5 0.4 0.9 -0.0 0.0 -0.4 0.6 1.6 0.2 -0.2 0.8 -0.8 0.4 -1.3 0.4 -0.8
Stomach or abdominal pain in last month 0.6 0.7 2.5 -1.0 -0.4 -1.6 -1.3 1.0 -0.5 -0.2 0.2 0.1 -0.8 1.0 -1.1 0.0 -0.9 0.0
Supplements: Glucosamine 0.5 0.7 2.5 -0.9 -0.9 -0.5 -1.2 0.5 -1.6 0.3 0.2 0.8 -1.1 -0.0 -1.1 0.5 -0.9 0.6
Diverticular disease/diverticulitis (self-reported) 1.4 1.7 4.6 -1.6 -1.8 -0.7 -0.6 0.4 -0.8 -0.5 1.7 0.4 -1.6 2.1 -1.5 0.7 -1.4 1.5
Medication: Atenolol 1.1 1.3 12.2 -1.0 -1.1 0.2 -0.5 0.9 -0.7 3.5 1.9 -0.2 -0.0 -0.1 -0.0 0.6 0.2 -0.3
Medication: Levothyroxine sodium 1.6 2.7 5.6 -1.9 -2.2 -2.2 -2.4 -0.7 -1.5 -1.1 1.4 1.4 -1.6 0.4 -2.3 -0.5 -2.0 1.1
Sitting height 0.4 2.8 6.0 -1.1 0.1 -0.5 0.7 2.3 1.5 1.8 -1.9 -2.1 1.6 -1.5 1.7 -1.7 2.1 -2.5
Chronic bronchitis/emphysema (father) 0.9 1.1 2.9 -0.7 0.1 -0.8 0.7 0.6 1.2 -1.7 -1.1 -1.2 1.0 -1.1 0.8 -1.6 0.8 -1.1
High blood pressure (mother) 1.2 1.7 3.3 -0.6 -1.4 -0.6 -1.8 -0.3 -1.6 -0.1 1.2 1.3 -1.8 1.1 -1.7 0.8 -1.7 1.5
Body mass index (BMI) 0.8 3.4 8.1 -0.1 -1.8 -1.6 -2.8 1.9 -1.6 0.4 2.4 2.6 -1.5 -0.4 -2.5 0.1 -2.8 1.1
Impedance of leg (left) 0.1 0.6 3.5 -0.4 0.3 0.1 0.4 -1.9 0.4 0.3 -0.1 -1.1 0.7 0.1 0.8 -0.2 1.1 -0.7
Leg predicted mass (left) 0.2 1.3 7.4 -0.6 -1.4 -1.3 -1.2 2.7 -0.6 -0.2 0.7 0.9 -0.6 -0.5 -1.3 -0.7 -1.4 0.1
Trunk fat mass 0.5 2.0 4.9 -0.1 -1.5 -1.2 -2.0 1.6 -0.9 0.9 2.2 1.8 -0.6 -0.5 -1.9 -0.5 -2.2 0.5
Waist circumference 0.5 2.0 5.7 0.1 -1.4 -0.9 -2.4 2.2 -1.0 1.1 1.6 1.9 -0.3 -1.2 -1.8 -0.3 -1.9 0.1
Number of incorrect matches in round 0.4 0.6 2.6 1.4 0.9 1.6 0.5 -0.4 0.4 -1.3 0.1 0.2 0.3 -0.1 0.8 0.8 0.5 0.3
Past tobacco smoking 0.6 1.1 3.0 1.2 -0.7 1.2 -0.2 1.2 -1.1 0.1 1.5 1.7 -0.6 -0.3 -0.6 1.6 -1.0 1.0
Alcohol usually taken with meals 1.1 1.8 5.8 1.0 1.1 2.0 2.0 -1.0 1.0 2.4 -1.2 -0.7 1.2 -1.1 1.6 0.0 1.1 -0.7
Nervous feelings 1.3 2.5 6.3 -0.9 1.9 0.2 2.5 1.8 2.4 -1.1 -0.9 -2.2 1.3 0.7 2.1 -1.1 1.6 -0.7
Frequency of tenseness / restlessness in last 2 weeks 0.5 0.8 3.5 -1.3 1.2 -1.9 -0.8 1.2 0.3 -0.2 0.9 -0.1 -0.5 -0.0 -0.4 -1.0 -0.7 -0.2
Hearing difficulty/problems with background noise 0.4 0.6 2.6 1.5 0.9 1.6 0.3 -0.5 0.1 0.9 0.0 0.5 0.3 -1.1 0.6 0.6 0.3 -0.1
Hair/balding pattern: Pattern 2 2.1 2.7 9.1 -0.9 -0.7 -1.8 -3.0 -2.2 -1.7 1.2 1.7 1.1 -2.3 0.9 -2.1 0.5 -1.8 0.6
Had menopause 0.3 0.3 1.5 -0.3 1.2 0.2 0.8 -0.9 0.4 0.2 -0.5 0.1 0.6 -0.7 0.3 -0.7 0.1 -0.1
Had other major operations 0.7 0.8 2.7 -1.5 -1.0 -1.5 -0.6 -1.6 -0.8 0.6 -0.1 -0.0 -0.8 -0.0 -1.0 -0.6 -0.6 0.2
Forced vital capacity (FVC) 0.4 1.4 6.5 -1.7 -1.3 -1.2 0.3 0.3 -0.5 -2.5 1.2 -0.6 -1.7 1.6 -0.3 0.7 -0.3 0.5
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.3 7.8 -1.3 -1.1 -2.8 -1.0 -0.2 -0.5 -1.9 -0.3 -0.1 -0.6 -0.5 -0.9 -1.4 -0.6 -0.2
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 1.4 1.2 0.9 -0.1 -1.0 -0.0 -0.0 -0.1 0.2 1.0 -0.3 0.0 -0.6 0.0 -1.1 0.6
Qualifications: None of the above 0.2 0.4 1.4 -0.7 0.0 -0.2 -0.3 0.4 -0.4 -1.2 -0.6 -0.1 -1.0 0.8 -0.4 0.9 -0.2 0.6
Financial difficulties in last 2 years 2.2 2.9 6.5 -0.7 -1.4 -1.7 -2.3 -1.6 -1.0 0.1 2.5 1.2 -2.3 1.9 -2.2 0.7 -2.3 1.4
Mouth/teeth dental problems 0.3 0.5 1.6 0.4 0.0 0.8 1.1 0.3 0.6 1.3 -0.1 -0.3 0.8 -0.8 1.0 -0.1 0.9 -0.6
Heart attack 0.7 0.9 2.0 -1.1 1.2 -0.8 0.4 1.1 1.2 1.1 -0.5 -1.4 0.8 -0.5 0.7 -1.0 0.8 -1.4
Allergy 0.4 1.0 3.9 -0.7 1.0 0.7 2.0 -0.1 0.6 0.9 0.4 -1.4 0.9 0.4 1.1 0.2 1.5 -0.8
Pain all over the body in last month 0.5 0.6 3.0 -0.6 1.2 -1.1 -0.4 0.7 0.6 -1.7 -0.6 -0.2 -0.2 -0.3 -0.0 -1.0 -0.4 -0.2
Diabetes (self-reported) 0.9 1.4 3.0 -1.1 -1.1 -1.2 -1.7 0.5 -1.7 -0.2 1.6 0.8 -1.7 0.5 -1.5 0.8 -1.4 0.5
Hayfever/allergic rhinitis (self-reported) 1.0 1.3 6.8 2.6 -0.5 1.7 -0.1 -1.6 0.1 0.4 0.0 1.6 0.0 -0.2 -0.2 1.0 -0.9 1.4
Medication: Ramipril 1.9 2.5 6.1 -0.8 -0.6 -1.5 -2.5 -1.2 -2.0 -0.3 1.9 1.3 -2.4 0.5 -2.1 0.7 -2.1 1.1
Medication: Simvastatin 0.8 1.1 2.4 -0.1 -1.1 -0.2 -1.4 -0.8 -1.5 1.2 1.4 1.0 -1.2 0.4 -1.4 1.2 -0.9 0.5
Fluid intelligence score 0.4 0.9 4.9 0.5 -0.2 0.4 0.1 0.6 0.8 2.2 -0.6 -0.4 1.1 -1.3 1.1 -0.7 1.0 -1.1
Illnesses of siblings 4.0 5.6 13.8 -0.9 1.3 0.4 2.1 1.7 2.1 0.7 -2.2 -3.6 2.6 -2.1 3.2 -1.6 3.7 -3.7
Neuroticism score 0.3 0.7 2.7 -1.1 0.1 -0.8 -0.2 0.7 -0.1 -1.2 1.6 -0.1 -0.9 1.2 -0.4 0.1 -0.7 0.7
Weight 0.4 1.8 7.2 -0.5 -1.5 -1.6 -1.8 2.7 -0.7 -0.0 1.3 1.4 -0.6 -0.8 -1.6 -0.8 -1.8 0.0
Impedance of arm (right) 0.4 1.8 6.5 2.1 0.3 2.5 1.8 -1.3 0.8 2.1 0.9 -0.3 1.0 0.8 1.3 0.8 0.9 0.5
Arm fat percentage (right) 0.6 2.4 6.8 0.8 -1.8 -0.7 -1.9 1.9 -0.9 1.4 2.6 2.2 -0.7 -0.4 -1.8 -0.2 -2.2 0.9
Trunk fat-free mass 0.5 2.6 13.7 -1.4 -0.4 -2.1 -0.7 3.7 0.4 -1.5 -1.6 -0.8 0.6 -2.1 0.1 -2.1 0.5 -1.9
Hip circumference 0.8 3.4 8.5 0.2 -2.0 -1.1 -2.9 1.8 -1.9 -0.6 2.0 2.6 -1.7 -0.1 -2.6 0.6 -2.8 1.1
Time employed in main current job 3.7 4.3 12.2 1.8 -3.1 2.2 -1.0 -0.5 -2.1 1.2 2.8 2.4 -1.7 1.3 -1.2 3.5 -1.7 2.2
Alcohol intake versus 10 years previously 0.1 0.2 1.6 0.0 1.2 -0.3 0.0 -0.6 0.2 0.5 -0.1 -0.5 -0.5 0.5 -0.2 0.1 0.1 -0.4
Father’s age at death 0.3 0.4 2.2 -0.0 1.5 -0.0 0.6 -0.2 0.9 -0.7 -0.3 -0.6 0.7 0.2 0.6 -0.6 0.3 0.1
Worrier / anxious feelings 0.3 0.5 2.2 0.1 0.6 1.1 1.5 0.9 0.1 0.1 1.3 0.1 -0.2 0.6 0.3 0.8 -0.2 0.7
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.1 2.7 -1.1 -1.0 -1.6 -1.1 -0.5 -0.4 -0.4 1.6 0.6 -1.2 1.4 -1.2 -0.2 -1.4 0.8
Falls in the last year 0.9 1.2 4.2 -2.0 0.4 -1.7 0.6 1.6 1.0 -0.2 -0.5 -1.1 0.6 -0.5 0.3 -2.1 0.5 -0.9
Hair/balding pattern: Pattern 3 2.8 4.2 9.2 0.3 1.9 0.8 3.0 1.1 2.2 -2.5 -2.9 -2.3 2.6 -0.5 2.5 -1.5 2.6 -1.2
Number of live births 0.4 0.6 3.7 0.2 0.4 -0.1 0.3 -0.8 -0.6 -1.9 -0.3 0.6 -1.2 0.5 -0.5 1.0 -0.5 0.9
Forced expiratory volume in 1-second (FEV1) 0.2 0.7 1.6 -1.2 -1.0 -0.7 0.7 0.8 -0.2 -0.9 1.2 -1.0 -0.8 1.0 0.4 0.6 0.5 -0.1
Pulse rate 2.1 3.6 12.2 -2.9 1.4 -2.4 1.0 1.8 1.8 0.9 -1.5 -2.2 1.2 -1.3 0.9 -3.5 1.1 -2.1
Happiness 0.8 1.0 4.8 -0.5 2.2 -0.4 0.9 1.1 1.5 0.7 -0.3 -1.3 0.8 -0.0 0.9 -0.9 0.7 -0.9
Noisy workplace 0.8 1.0 2.7 -0.4 -1.4 -0.8 -1.6 0.3 -0.8 -0.1 1.0 1.2 -1.3 0.0 -1.2 0.5 -1.5 1.0
Qualifications: A levels/AS levels or equivalent 0.4 0.8 3.9 2.0 0.3 1.6 0.1 0.0 0.2 1.8 0.3 0.6 0.6 0.3 0.5 0.9 0.3 0.5
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.6 3.2 0.2 0.2 -0.3 -0.6 -1.8 -0.7 0.5 0.4 1.2 -0.6 0.0 -0.9 0.1 -1.3 0.7
Mouth/teeth dental problems: Dentures 0.2 0.3 1.3 -1.1 -0.5 -0.8 -0.1 0.8 -0.4 -0.6 -0.7 -0.4 -0.4 -0.1 -0.3 -0.0 -0.1 -0.1
Asthma 0.7 1.4 4.0 0.3 -1.6 -0.9 -2.0 0.4 -0.7 -0.5 1.0 1.3 -1.4 0.8 -1.5 0.4 -2.0 1.2
Medication: Ibuprofen (e.g. Nurofen) 1.2 1.5 8.2 -2.5 -0.1 -2.9 -0.6 0.2 0.2 -0.8 -0.2 -0.8 0.1 -0.9 -0.5 -1.9 -0.0 -1.1
Medication: Cholesterol lowering 0.3 0.5 1.5 -0.5 -0.9 -0.7 -1.2 0.0 -0.7 0.7 1.1 0.6 -0.8 0.1 -0.9 0.3 -0.7 -0.0
Depression (self-reported) 0.3 0.4 3.7 0.5 -0.0 0.1 0.6 0.2 0.5 -1.9 0.0 -0.5 0.3 0.0 0.6 -0.4 0.5 -0.6
Medication: Lansoprazole 1.7 1.9 3.8 0.1 -1.9 0.6 -1.2 -0.5 -1.8 1.3 1.6 1.7 -1.1 0.9 -1.8 1.4 -1.8 1.5
Prospective memory result 0.7 0.8 4.3 -0.6 0.1 -0.2 0.6 -0.5 0.0 -1.0 1.0 0.1 -1.0 2.1 -0.6 0.6 -1.0 1.4
Lung cancer (father) 0.4 0.5 1.3 -0.0 0.6 0.8 1.1 0.4 0.7 -0.5 -1.1 -0.7 0.9 0.1 0.8 -0.3 1.1 -0.2
Illnesses of mother 0.2 0.3 1.9 1.4 0.3 0.7 0.3 -0.6 -0.1 0.5 -0.5 0.5 0.3 -0.1 0.1 0.6 0.1 0.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.5 1.7 -1.2 -0.8 -1.2 -0.3 0.0 -0.3 -0.6 1.3 -0.5 -1.0 0.5 -0.1 0.1 0.1 -0.2
Pulse wave Arterial Stiffness index 0.2 0.2 1.0 -0.7 -1.0 -0.1 -0.2 0.8 -0.2 0.3 0.8 0.1 -0.4 0.2 -0.3 -0.1 -0.4 0.0
Impedance of arm (left) 0.4 2.1 6.6 1.8 0.3 2.6 1.8 -2.4 0.4 2.0 0.9 -0.4 0.7 1.6 1.0 1.3 0.7 0.8
Arm fat mass (right) 0.6 2.6 6.0 0.1 -1.9 -1.3 -2.3 2.0 -1.2 0.9 2.2 2.3 -1.0 -0.5 -2.1 -0.4 -2.5 0.8
Trunk predicted mass 0.4 2.5 13.5 -1.3 -0.5 -2.0 -0.6 3.7 0.4 -1.5 -1.6 -0.7 0.5 -2.1 0.0 -2.0 0.3 -1.8
Standing height 0.2 2.2 4.5 -0.7 0.2 -0.3 1.7 2.1 1.5 -1.1 -1.9 -2.1 1.6 -0.8 1.5 -1.6 1.7 -1.8
Length of working week for main job 1.9 2.1 5.9 0.1 -1.7 -0.5 -1.8 0.9 -1.5 -0.9 2.4 1.4 -2.0 0.9 -1.4 1.3 -1.8 1.3
Exposure to tobacco smoke at home 1.5 1.7 8.5 -2.9 -0.2 -2.9 -0.4 -0.6 0.1 0.3 0.3 -0.8 -0.5 -0.2 -1.1 -2.2 -0.7 -0.5
Breastfed as a baby 0.7 0.8 3.6 1.5 -0.9 1.9 -0.3 -0.3 -1.0 0.2 -0.6 0.9 -0.1 0.1 -0.3 1.6 -0.2 0.7
Tense / ‘highly strung’ 0.2 0.4 1.3 -0.5 0.7 -1.2 -0.9 -0.3 -0.4 -0.6 0.9 0.1 -0.2 0.2 -0.8 -0.6 -0.4 -0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.6 0.7 1.3 0.4 0.4 0.3 0.2 0.9 -0.8 -0.3 0.9 -0.3 0.6 -0.2 0.6 -0.5
Hair/balding pattern: Pattern 4 0.5 1.2 9.9 -0.3 -1.4 0.1 0.4 -1.6 -0.4 -3.1 -1.0 0.5 0.3 0.5 -0.8 -0.3 -0.6 0.7
Birth weight of first child 0.4 0.8 5.0 0.4 0.2 1.3 0.1 0.3 0.1 2.2 -0.1 -0.5 0.7 -0.7 0.9 0.5 1.3 -0.7
Peak expiratory flow (PEF) 0.2 0.5 1.8 -0.8 -0.7 0.2 1.4 -0.0 0.5 0.2 0.4 -1.1 -0.1 1.2 0.9 0.6 0.8 0.0
Pulse wave reflection index 0.9 1.1 2.9 0.6 -1.6 0.9 -0.7 0.7 -1.3 -0.6 1.5 1.0 -1.1 0.7 -0.7 1.7 -0.7 0.8
Ever highly irritable/argumentative for 2 days 0.9 1.1 3.0 1.2 1.4 0.7 -0.7 1.7 0.6 0.6 -0.5 -0.4 1.2 -1.2 1.1 -0.4 1.2 -1.3
Loud music exposure frequency 1.0 1.1 4.5 -1.6 0.1 -2.1 -1.9 -0.3 -0.5 -0.5 0.1 -0.1 -0.6 -1.6 -0.6 -1.1 -0.2 -1.1
Qualifications: O levels/GCSEs or equivalent 0.2 0.2 1.0 -0.4 0.2 -0.4 0.3 0.3 0.1 -0.9 -1.0 -0.6 -0.3 0.7 0.3 -0.1 0.3 -0.2
Mouth/teeth dental problems: Bleeding gums 1.8 2.4 4.8 1.5 -0.9 0.1 -2.0 -1.7 -1.4 -1.4 1.9 2.2 -1.4 0.7 -1.7 1.3 -1.8 1.8
Blood clot in the leg (DVT) 1.0 1.3 3.0 -1.4 1.6 -0.9 1.4 1.6 1.0 -0.2 -1.4 -1.2 0.8 -0.4 0.7 -1.7 0.8 -0.9
Medication: Paracetamol 1.9 3.2 7.7 -1.5 1.5 -1.7 0.2 2.5 1.5 0.1 -1.1 -1.9 1.2 -2.7 1.3 -2.7 1.4 -2.8
Headache pain in last month 0.6 1.0 4.0 -0.8 1.1 -1.3 -0.4 2.0 0.7 0.9 -0.0 -0.9 0.5 -1.1 0.5 -1.1 0.8 -1.6
Medication for cholesterol, blood pressure or diabetes 1.1 1.7 5.1 0.9 1.6 1.0 2.3 -0.1 1.2 -0.0 -1.9 -1.1 1.6 -0.9 1.7 -0.4 1.8 -1.0
Glaucoma (self-reported) 0.6 0.8 6.2 0.0 -0.7 -0.6 0.3 -0.3 0.1 -2.5 0.3 0.7 -0.8 0.7 -0.8 -0.0 -0.9 1.0
Gout (self-reported) 0.1 0.1 0.6 0.2 0.1 0.7 0.3 0.4 0.2 0.1 -0.1 -0.2 0.3 0.8 0.1 0.2 0.2 0.1
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 3.9 -1.1 -2.0 -1.1 -1.1 -0.4 -0.8 -0.4 1.5 1.2 -1.1 -0.1 -1.2 -0.4 -1.5 1.0
Medication: Amlodipine 1.0 1.4 5.1 0.1 -1.5 0.4 -1.2 -0.2 -1.3 2.1 2.3 1.1 -0.8 0.2 -1.2 1.0 -1.2 0.7
Medication: Ventolin 100micrograms inhaler 1.8 2.3 6.4 0.3 -1.0 -0.8 -1.1 -2.0 -0.8 -2.5 -0.2 1.7 -1.7 1.8 -1.7 0.6 -2.1 2.0
Birth weight 1.7 3.7 7.9 -0.2 1.9 0.2 1.9 -0.5 2.2 0.7 -2.4 -2.0 2.0 -2.8 2.4 -2.2 2.1 -2.3
Chronic bronchitis/emphysema (mother) 0.7 0.8 2.6 -1.0 1.2 -1.5 -0.2 -1.0 0.9 -1.0 -0.6 -0.9 -0.1 -0.6 0.2 -1.6 0.0 -0.9
High blood pressure (siblings) 3.3 4.8 11.0 0.8 -2.2 -0.1 -1.7 -1.0 -2.2 -0.5 2.2 3.2 -2.4 1.9 -2.9 1.9 -3.3 3.3
Forced vital capacity (FVC), Best measure 0.4 1.4 3.6 -1.4 -1.5 -1.4 -0.6 -0.4 -0.8 -1.8 1.7 0.2 -1.9 1.4 -0.9 0.5 -0.8 0.9
Body fat percentage 0.5 2.0 6.5 0.4 -1.3 -0.9 -1.9 1.1 -0.9 1.1 2.5 2.1 -0.6 -0.3 -1.8 -0.2 -2.3 0.8
Leg fat percentage (right) 0.3 1.2 3.8 -0.3 -0.7 -1.4 -1.5 1.9 -0.1 0.9 1.4 1.1 0.1 -0.9 -1.1 -1.1 -1.3 -0.3
Arm fat-free mass (right) 0.3 1.7 7.7 -1.5 -0.7 -2.2 -1.4 2.8 -0.3 -1.2 -0.6 0.2 -0.2 -1.6 -0.9 -1.4 -0.7 -1.0
Exposure to tobacco smoke outside home 0.8 1.1 4.3 -1.7 -0.5 -2.1 -1.3 -0.4 -1.0 -0.6 -0.1 0.2 -0.7 -1.3 -1.2 -1.0 -0.7 -0.7
Comparative body size at age 10 0.7 1.8 5.6 1.3 0.2 0.7 -0.3 -0.4 -0.4 -2.1 0.1 1.7 -0.9 2.0 -1.2 1.1 -1.9 2.4
Number of full brothers 2.2 2.8 7.8 0.6 -0.9 -0.5 -1.3 -0.4 -1.7 0.1 2.2 2.5 -2.1 0.9 -2.2 1.0 -2.8 2.3
Worry too long after embarrassment 1.1 1.8 5.3 -0.6 1.5 0.1 2.3 0.3 1.7 -2.3 -0.7 -2.0 1.0 0.6 1.7 -0.9 1.3 -0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 2.6 0.3 -0.1 -0.5 -0.1 0.1 -0.1 -1.6 0.4 0.7 -0.4 1.2 -0.8 -0.0 -0.8 0.9
Wheeze or whistling in the chest in last year 0.3 0.6 2.1 0.1 0.6 -0.7 -0.4 1.4 0.2 -0.9 -0.4 1.0 -0.2 0.4 -0.9 -0.6 -1.5 0.8
Number of children fathered 0.9 1.0 3.1 -0.3 0.8 -0.1 1.2 0.1 0.7 -0.1 -1.8 -1.3 1.2 -0.3 1.3 -0.9 1.4 -1.1
Reason for reducing amount of alcohol drunk: Health precaution 2.1 2.4 4.1 -0.6 1.9 -0.3 1.7 -1.9 2.0 -1.1 -1.4 -1.9 1.4 -0.8 1.9 -1.7 2.0 -1.5
Age at first live birth 0.3 0.5 2.0 1.1 -0.9 1.4 0.0 -0.2 -0.3 1.4 0.6 0.0 0.6 -0.2 0.5 0.7 0.7 -0.2
Pulse wave peak to peak time 0.2 0.2 0.7 0.7 0.8 0.1 0.2 -0.8 0.2 -0.4 -0.7 -0.2 0.4 0.0 0.2 0.1 0.4 -0.0
Health satisfaction 0.4 0.5 2.2 0.3 1.5 -0.2 0.4 0.9 1.1 0.4 0.1 -0.7 0.9 -0.1 0.4 -0.9 0.5 -0.5
Shortness of breath walking on level ground 1.1 1.3 4.1 -0.4 -1.5 -0.6 -2.0 -0.5 -1.9 0.1 0.7 1.2 -1.6 -0.3 -1.4 0.9 -1.2 0.4
Qualifications: College or University degree 0.7 2.1 9.1 3.0 1.2 2.3 1.5 -1.1 1.1 2.0 0.4 0.8 1.6 -1.4 1.5 0.1 0.4 -0.1
Eye problems/disorders: None of the above 2.1 2.4 4.5 1.3 2.0 1.6 1.5 2.1 1.3 1.7 -0.7 -0.8 1.8 -2.1 1.8 -0.6 1.6 -1.4
Mouth/teeth dental problems: Loose teeth 0.5 0.5 1.8 -1.3 0.1 -1.3 -1.2 -0.0 -0.7 -0.1 -0.5 -0.3 -0.5 -0.9 -0.4 -0.7 0.0 -0.8
Emphysema/chronic bronchitis 0.7 0.8 3.9 -0.2 1.0 -2.0 -0.5 0.1 0.4 -1.0 -0.5 0.6 -0.3 -1.1 -0.6 -1.8 -0.6 -0.6
Medication for pain relief, constipation, heartburn 0.8 1.3 3.7 1.2 -0.9 1.2 -0.4 -1.9 -1.0 -0.5 0.3 1.0 -0.8 1.7 -0.5 1.8 -0.7 1.6
Neck or shoulder pain in last month 0.2 0.3 3.0 -0.1 0.3 -0.4 0.2 0.0 -0.0 1.7 0.5 0.1 0.1 -0.6 0.0 -0.3 0.1 -0.4
Medication: Blood pressure 2.1 3.7 10.1 -1.9 -2.1 -1.6 -3.2 0.4 -2.2 0.2 2.6 1.2 -2.3 1.5 -2.5 0.6 -2.4 1.3
Angina (self-reported) 0.8 1.0 5.3 -1.7 -0.1 -0.9 -0.1 0.9 0.1 2.3 0.4 -1.1 0.2 -0.7 0.2 -0.8 0.7 -1.4
Migraine (self-reported) 0.5 0.7 1.9 1.0 -1.4 0.9 -0.9 -0.2 -0.9 1.0 0.6 1.1 -0.3 -0.1 -0.4 1.3 -0.3 0.4
Medication: Ibuprofen 1.6 1.9 10.3 -2.2 -0.1 -3.2 -0.9 -0.6 -0.1 -2.4 -0.1 -0.1 -0.3 -1.1 -0.9 -2.0 -0.7 -0.7
Medication: Allopurinol 0.3 0.4 2.0 0.2 -0.7 0.3 -0.2 0.2 -0.3 0.6 0.9 0.6 -0.2 1.4 -0.6 0.5 -0.6 0.9
Medication: Omeprazole 1.7 2.0 5.7 -0.2 2.2 0.5 1.8 0.0 1.8 2.4 -0.8 -1.7 1.5 0.3 1.3 -1.4 1.5 -1.1
Medication: Seretide 50 evohaler 0.4 0.4 1.9 1.3 -0.8 0.4 -0.2 1.4 -0.1 0.1 0.5 1.0 0.1 -0.4 -0.3 0.1 -0.4 0.2
Mean time to correctly identify matches 4.3 8.2 20.0 2.9 -3.9 2.7 -2.3 -0.6 -3.7 0.3 3.8 4.5 -2.1 -0.4 -2.4 3.9 -2.5 2.8
Heart disease (mother) 0.2 0.2 1.0 -1.0 -0.3 -0.6 -0.7 -0.5 -0.4 0.5 0.3 0.1 -0.3 -0.2 -0.3 -0.2 -0.2 -0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.9 6.3 -2.5 -0.1 -1.2 -0.4 0.5 0.1 0.3 0.1 -1.7 -0.4 0.9 0.1 -0.3 0.5 -0.7
Whole body fat mass 0.5 2.0 4.5 -0.2 -1.6 -1.3 -2.0 2.0 -0.9 0.8 2.1 1.8 -0.6 -0.5 -1.8 -0.5 -2.1 0.4
Leg fat mass (right) 0.5 2.0 5.4 -0.7 -1.5 -1.9 -2.1 2.3 -0.7 0.5 1.7 1.4 -0.5 -0.8 -1.7 -1.0 -1.9 -0.0
Arm predicted mass (right) 0.3 1.4 7.0 -1.2 -0.6 -1.9 -1.2 2.6 -0.3 -0.9 -0.6 0.2 -0.1 -1.6 -0.7 -1.3 -0.6 -1.0
Pulse rate, automated reading 0.7 2.2 8.7 -1.8 -0.1 -1.0 1.0 1.2 1.2 3.0 -0.4 -1.4 1.2 -1.6 1.0 -2.5 1.2 -1.4
Alcohol intake frequency. 1.1 2.4 6.2 1.2 -1.4 1.7 -1.1 1.6 -2.1 2.5 1.6 1.7 -1.2 -0.3 -1.0 2.5 -1.0 0.9
Comparative height size at age 10 0.2 1.3 4.6 -1.4 -1.5 -1.4 -0.7 2.1 -0.6 -1.8 1.0 0.3 -0.8 0.6 -0.9 -0.5 -0.9 0.5
Number of full sisters 0.7 0.9 2.2 0.3 -0.2 -0.4 -0.7 0.9 -0.8 -0.9 1.2 1.4 -1.3 0.5 -1.0 0.4 -1.5 1.3
Suffer from ‘nerves’ 1.1 1.7 4.0 -0.2 1.4 -0.1 1.3 0.8 1.3 -0.2 -1.0 -1.9 1.4 -0.9 1.6 -1.2 1.9 -2.0
Overall health rating 1.0 2.2 6.3 -1.1 -1.0 -2.0 -2.3 0.3 -1.3 0.6 2.5 1.4 -1.2 -0.4 -2.2 -0.8 -1.9 0.4
Chest pain or discomfort 0.2 0.3 1.0 0.0 0.7 -0.7 -0.2 0.8 0.2 0.2 -0.2 0.3 0.3 -0.6 -0.3 -1.0 -0.7 -0.3
Had major operations 0.5 0.6 3.8 -0.2 0.9 -1.2 0.1 -1.9 0.2 -0.3 -0.4 0.0 -0.1 1.0 -0.7 -0.6 -0.7 0.6
Age at last live birth 0.3 0.5 1.4 1.2 -0.5 1.1 0.1 -0.1 0.2 1.2 0.4 0.0 0.7 -0.8 0.8 0.3 0.8 -0.4
Family relationship satisfaction 0.7 0.9 3.3 -0.5 1.6 -1.4 0.3 0.4 1.2 0.6 -0.3 -0.8 0.8 -0.6 0.5 -1.8 0.5 -0.9
Leg pain on walking 0.8 1.0 5.4 0.1 -0.7 -0.9 -2.3 0.5 -1.0 0.2 1.1 1.1 -1.3 -0.8 -1.0 -0.1 -1.0 0.0
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 2.7 -1.4 -0.7 -1.6 -0.5 0.6 -0.3 -0.6 0.5 -0.6 0.0 -0.8 -0.6 -0.8 -0.0 -1.0
Commuting to job workplace: Car/motor vehicle 1.2 1.3 3.0 1.0 -1.0 1.2 -0.3 -1.7 -1.2 1.2 1.7 1.1 -0.9 0.6 -0.6 1.7 -0.9 0.9
Illness, injury, bereavement, stress in last 2 years 1.8 2.2 5.0 1.7 0.8 2.2 1.8 1.1 0.3 0.6 -2.1 -0.4 1.6 -2.2 1.6 0.3 1.9 -1.1
Medication: Aspirin 0.7 0.9 5.0 -0.3 -1.1 0.3 -0.3 1.2 -0.7 2.2 1.7 0.5 -0.7 0.2 -0.4 1.0 -0.5 0.5
Supplements: Vitamin C 0.8 0.9 4.6 0.3 -2.1 -0.0 -0.6 0.7 -1.1 -0.2 1.6 1.1 -0.8 0.4 -0.7 0.8 -0.9 1.0
Knee pain experienced in last month 1.2 1.9 5.1 -1.0 -0.4 -1.8 -2.2 0.5 -2.0 -0.5 1.0 1.5 -1.7 0.2 -2.3 0.1 -1.8 0.8
Hypertension (Self-reported) 3.0 8.5 19.1 -1.4 -3.2 -2.1 -4.4 1.0 -3.4 0.7 4.3 3.0 -3.6 1.2 -3.7 1.6 -3.9 2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.1 1.3 5.8 0.4 -0.5 2.0 -0.4 2.0 -0.8 2.4 0.7 -0.0 0.7 -0.2 0.3 1.5 0.5 -0.4
Illnesses of father: Heart disease 1.3 1.8 11.1 -0.0 -0.5 0.1 0.5 -3.3 -0.9 0.0 0.1 0.8 -1.2 2.0 -1.1 1.2 -1.4 1.8
Illnesses of siblings: Diabetes 2.7 3.4 9.5 -0.9 -1.2 -1.7 -2.0 -1.2 -1.5 0.1 2.3 2.2 -2.2 1.4 -2.6 0.3 -3.1 2.0
Smoking status: Previous 0.5 0.8 2.1 -0.9 0.5 -0.9 0.3 -0.9 1.2 -0.9 -1.2 -1.5 0.4 0.3 0.7 -1.4 0.9 -0.6
Forced expiratory volume in 1-second (FEV1), predicted 2.0 4.2 7.6 -0.9 2.1 -0.5 1.6 1.1 2.5 -0.1 -1.9 -2.7 2.6 -1.7 2.4 -2.8 2.5 -2.6
Whole body fat-free mass 0.3 1.8 12.3 -1.1 -0.8 -1.8 -1.0 3.5 -0.1 -1.1 -0.7 -0.1 0.1 -1.6 -0.5 -1.6 -0.3 -1.2
Leg fat-free mass (right) 0.2 1.3 4.6 -0.7 -1.3 -1.4 -1.2 2.1 -0.9 -0.6 0.7 1.1 -1.0 -0.4 -1.5 -0.5 -1.6 0.3
Arm fat percentage (left) 0.5 2.2 6.1 0.7 -1.7 -0.7 -1.9 1.5 -1.0 1.4 2.5 2.2 -0.6 -0.3 -1.8 -0.1 -2.2 0.8
Average weekly red wine intake 0.3 0.5 3.8 -0.4 -0.9 0.3 0.8 -0.8 -0.0 1.9 0.4 -0.2 0.3 -0.4 0.6 0.2 0.3 -0.1
Handedness (chirality/laterality): Left-handed 0.5 0.6 2.8 0.0 -1.0 -0.0 -1.7 -0.6 -1.4 0.5 0.1 0.1 -0.5 -0.9 -0.2 1.0 0.5 -0.6
Mood swings 0.3 0.6 4.4 -0.3 -0.5 -0.6 -0.9 0.3 -0.5 0.7 2.1 0.5 -0.9 0.0 -0.5 0.2 -0.8 0.1
Loneliness, isolation 1.2 1.6 4.9 -1.7 1.8 -2.2 -0.3 0.7 1.2 -0.4 -0.7 -1.6 0.6 -0.1 0.2 -2.1 0.6 -1.5
Long-standing illness, disability or infirmity 0.3 0.5 2.5 -0.8 0.4 -1.4 -0.6 0.5 0.3 0.1 0.5 0.0 0.2 -0.2 -0.7 -1.6 -0.6 -0.2
Ever had bowel cancer screening 1.8 2.1 6.8 0.4 -1.1 0.6 0.6 -1.9 -0.4 -2.1 1.0 1.6 -1.5 1.8 -1.1 1.2 -1.7 2.6
Diabetes diagnosed by doctor 0.7 1.1 2.9 -0.7 -0.8 -1.2 -1.7 0.5 -1.4 -0.9 1.4 0.9 -1.4 -0.2 -1.3 0.3 -1.3 0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.6 1.7 0.8 0.4 -0.4 -1.3 -1.2 -0.6 -0.3 0.3 1.0 -0.8 0.1 -0.9 0.4 -1.0 0.5
Friendships satisfaction 1.0 1.2 3.8 0.9 2.0 0.3 1.3 1.4 1.2 0.7 0.4 -0.5 1.2 -1.1 1.0 -1.3 1.0 -0.9
Qualifications: nursing, teaching 1.9 2.9 6.1 1.6 0.3 1.9 1.5 1.3 1.9 2.3 -0.3 -0.7 2.5 -2.2 2.4 -1.2 1.9 -1.6
Commuting to job workplace: Walk 0.3 0.4 1.8 0.2 0.4 -0.3 -0.6 0.1 0.1 -0.4 -1.4 0.1 0.4 -0.9 -0.0 -1.2 0.1 -0.3
Eye problems/disorders: Cataract 0.8 0.9 1.9 0.0 -0.9 -0.4 -1.2 -1.0 -1.2 -0.2 0.0 1.1 -1.1 1.0 -1.4 0.7 -1.2 1.2
Mouth/teeth dental problems: Mouth ulcers 0.4 0.7 3.1 0.1 0.4 -0.3 -0.2 -1.8 -0.4 -0.9 0.7 0.7 -0.6 1.2 -1.0 0.3 -1.1 1.1
Medication for cholesterol 2.2 3.3 8.5 0.7 2.5 -0.2 2.0 0.4 2.9 -1.9 -2.0 -1.8 2.1 -0.2 2.1 -2.2 1.8 -1.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.4 1.5 0.2 0.7 -0.6 -1.2 0.4 -0.5 -0.4 0.4 0.8 -0.4 -0.1 -1.0 -0.2 -0.8 0.2
Back pain experienced in last month 2.7 3.9 11.0 -0.6 1.7 -1.0 0.2 1.4 1.8 0.7 -1.7 -2.0 2.2 -3.3 1.9 -2.9 2.0 -3.1
Mineral and other dietary supplements 1.6 2.1 4.2 1.8 1.1 1.2 1.0 1.6 1.7 0.8 -1.1 -0.8 2.1 -1.6 1.9 -0.7 1.8 -1.7
Breast cancer (self-reported) 0.4 0.4 2.0 -0.4 0.3 -0.3 -0.3 -1.4 -0.5 -0.9 0.4 0.3 -0.8 0.8 -0.7 0.3 -0.7 0.7
Asthma (self-reported) 1.0 2.0 5.5 0.3 -1.9 -1.0 -2.1 0.1 -1.0 -0.6 1.3 1.7 -1.7 0.9 -1.8 0.5 -2.4 1.5
Osteoporosis (self-reported) 0.3 0.3 1.6 -0.7 0.9 -0.3 0.5 1.2 0.6 0.5 -0.6 -0.6 0.5 0.3 0.1 -0.5 0.1 -0.3
Osteoarthritis (self-reported) 1.0 1.3 8.3 -0.2 -0.1 -1.4 -1.4 -0.6 -0.4 -2.9 -0.8 1.2 -0.7 -0.6 -1.3 -1.1 -1.2 0.6
Medication: Aspirin 0.6 0.7 4.7 -0.6 -0.8 0.3 -0.2 1.3 -0.7 2.2 1.2 0.3 -0.6 0.3 -0.3 0.9 -0.2 0.4
Medication: Gliclazide 4.3 4.8 11.9 -2.0 -2.1 -1.9 -1.9 0.0 -2.9 -1.1 2.8 1.8 -3.5 1.4 -3.0 1.2 -2.9 1.8
Illnesses of father: None of the above (group 1) 0.4 0.4 2.5 0.5 0.8 0.3 -1.0 1.6 -0.4 0.0 0.5 0.5 0.3 -1.1 -0.1 -0.2 0.2 -0.5
Smoking status: Current 0.7 1.1 5.0 -0.9 2.2 -1.3 0.1 -0.4 0.6 0.8 -1.2 -1.0 0.7 -1.0 0.2 -1.4 0.5 -1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.4 0.8 3.3 0.7 0.1 0.0 -0.2 -0.3 -0.2 -1.1 1.8 0.9 -1.2 1.2 -0.4 1.0 -0.8 1.3
Whole body water mass 0.3 1.6 11.4 -0.9 -0.7 -1.7 -0.9 3.4 -0.1 -1.0 -0.7 0.0 0.1 -1.6 -0.6 -1.4 -0.4 -1.1
Leg predicted mass (right) 0.2 1.3 4.0 -0.6 -1.3 -1.4 -1.3 2.0 -1.0 -0.6 0.7 1.2 -1.0 -0.4 -1.6 -0.5 -1.6 0.4
Arm fat mass (left) 0.6 2.6 6.0 0.4 -2.0 -1.0 -2.3 2.1 -1.2 0.9 2.2 2.4 -0.8 -0.5 -2.1 -0.2 -2.4 0.8
Number of self-reported non-cancer illnesses 3.2 5.6 14.1 0.7 -3.8 -0.1 -2.9 0.3 -2.6 -0.1 2.5 3.3 -2.6 0.7 -3.0 1.7 -3.4 2.5
Average weekly champagne plus white wine intake 1.2 1.6 6.3 2.5 0.2 2.4 0.4 1.0 -0.1 2.3 -0.2 0.6 1.4 -1.2 0.6 0.9 0.9 -0.4
Miserableness 0.9 1.6 4.2 -1.2 -2.1 -1.2 -1.5 -0.3 -1.6 0.7 1.9 0.9 -1.6 0.4 -1.2 0.6 -1.3 0.8
Guilty feelings 0.5 0.7 2.7 0.7 0.0 0.9 0.2 1.5 -0.0 -1.6 0.7 0.2 -0.6 1.1 0.1 1.1 -0.2 0.8
Wears glasses or contact lenses 1.2 1.4 4.8 -1.0 0.4 -0.4 0.4 -0.2 1.1 -0.6 -2.2 -1.3 1.1 -1.1 1.3 -1.7 1.3 -1.5
Ever taken oral contraceptive pill 1.3 1.5 5.1 -0.1 -1.2 -0.5 -2.3 -1.2 -1.0 0.9 1.3 1.3 -0.9 1.0 -1.7 0.4 -1.5 1.2
Hearing aid user 2.5 2.9 6.2 1.6 2.3 1.1 2.2 0.4 2.4 -0.6 -1.6 -1.3 2.5 -1.0 2.0 -1.6 1.7 -1.3
Mother’s age at death 0.4 0.5 3.8 -0.8 -2.0 -0.1 -0.1 1.6 0.0 0.0 -0.2 -0.0 -0.2 0.1 0.2 0.2 0.0 0.2
Financial situation satisfaction 0.5 0.6 2.4 -0.8 1.0 -1.5 -1.5 0.2 0.0 -0.7 -0.0 -0.6 -0.8 0.1 -0.3 -0.8 -0.0 -0.8
Tinnitus: Yes, now most or all of the time 1.4 1.6 3.0 0.7 1.7 0.6 0.7 0.4 1.4 0.6 -1.4 -1.6 1.6 -1.0 1.7 -0.7 1.7 -1.7
Commuting to job workplace: Public transport 0.5 0.6 1.4 -0.9 1.2 -0.7 -0.0 0.9 0.6 1.2 -0.0 -0.9 0.5 -0.0 0.1 -0.9 0.4 -1.0
Eye problems/disorders: Glaucoma 1.1 1.3 4.0 0.3 -1.9 -0.4 -0.8 -0.5 -0.8 -2.0 0.7 1.6 -1.1 0.6 -1.4 0.6 -1.4 1.2
Medication: Blood pressure 2.7 5.2 10.1 0.1 -2.9 -0.1 -2.9 -0.1 -2.9 1.6 3.2 2.6 -2.6 0.8 -2.6 2.5 -2.9 2.0
Pain type(s) experienced in last month: Hip pain 0.4 0.5 1.7 -1.0 0.3 -0.5 0.9 -0.1 0.7 0.3 0.6 -0.7 0.5 -0.8 0.4 -1.3 0.4 -0.8
Supplements: Fish oil (including cod liver oil) 1.9 2.5 5.8 -1.3 -1.0 -1.3 -1.4 -1.3 -1.8 -1.3 0.6 0.9 -2.3 2.4 -2.0 1.1 -1.8 1.9
High cholesterol (Self-reported) 0.9 1.5 3.8 1.6 -1.8 1.3 -0.4 0.4 -1.0 1.0 1.8 1.9 -0.6 -0.1 -0.9 1.4 -1.2 1.2
Medication: Bendroflumethiazide 2.4 3.7 8.3 0.0 -2.9 0.4 -2.1 -0.5 -2.8 2.0 2.8 1.9 -1.8 0.7 -1.8 2.6 -1.7 1.4
Medication: Paracetamol 1.4 2.1 5.2 -1.6 1.1 -1.4 -0.4 2.1 0.6 0.2 -1.4 -1.6 0.9 -2.1 0.8 -2.0 1.2 -2.3
Medication: Lisinopril 3.4 4.4 9.7 -0.2 -3.1 -0.5 -2.7 1.0 -2.7 0.5 3.1 2.3 -2.1 1.0 -2.6 1.6 -2.7 1.8
Medication: Atorvastatin 0.7 0.8 4.7 -0.7 -1.0 0.2 0.0 2.2 -0.6 1.9 0.7 -0.6 -0.2 -0.4 0.4 0.8 0.5 -0.9
Illnesses of father: High blood pressure 0.5 0.7 5.9 -0.0 -2.4 0.4 -0.1 0.2 -0.2 1.4 1.0 -0.2 -0.3 0.2 0.3 0.8 0.2 0.0
Alcohol drinker status: Never 4.8 5.8 12.6 -0.4 -3.6 0.1 -2.7 -0.9 -3.3 1.6 2.9 2.5 -2.9 1.3 -2.6 2.9 -2.6 2.4
Ever smoked 0.4 0.8 2.1 -0.7 0.8 -0.6 0.5 -1.1 0.9 1.0 -1.1 -1.5 0.6 -0.0 0.6 -0.9 1.1 -1.0
Basal metabolic rate 0.3 1.6 10.7 -0.9 -1.1 -1.8 -1.3 3.3 -0.3 -0.6 -0.0 0.4 -0.2 -1.4 -0.9 -1.3 -0.8 -0.8
Leg fat percentage (left) 0.3 1.1 2.7 -0.5 -0.6 -1.6 -1.6 1.1 -0.4 0.5 1.3 1.2 -0.2 -0.9 -1.4 -1.1 -1.6 -0.1
Arm fat-free mass (left) 0.3 1.6 9.5 -1.0 -1.0 -1.8 -1.3 3.1 -0.5 -0.9 -0.4 0.5 -0.2 -1.5 -1.0 -1.1 -0.8 -0.7
Number of operations (self-reported) 0.5 0.8 5.2 0.4 -0.6 0.2 -0.4 -2.3 -0.9 1.3 -0.7 0.7 -0.5 0.2 -0.8 0.7 -0.6 0.7
Average weekly beer plus cider intake 1.2 1.8 11.0 -1.1 0.2 -1.0 0.4 3.3 1.0 -2.7 -0.3 -1.4 0.4 0.2 0.9 -0.6 0.8 -0.9
Irritability 0.5 0.8 2.9 -0.8 -0.7 -0.2 -0.9 0.0 -1.3 0.7 1.7 0.5 -1.0 0.9 -0.8 1.1 -0.6 0.7
Risk taking 0.2 0.3 1.7 -0.7 -0.2 -0.7 0.1 -1.1 0.1 0.4 1.3 0.2 -0.3 -0.1 -0.3 -0.6 -0.4 0.1
Ever had prostate specific antigen (PSA) test 0.8 0.9 2.5 0.6 0.3 1.1 1.3 -0.8 1.4 0.1 -0.6 -1.1 1.0 0.6 1.6 0.3 1.2 -0.3
Fractured/broken bones in last 5 years 0.5 0.7 3.0 -1.7 1.2 -1.7 0.5 0.5 0.5 -0.2 0.4 -0.6 -0.2 -0.0 -0.3 -1.2 -0.4 -0.2
Age started oral contraceptive pill 0.9 1.1 3.3 -0.7 1.0 0.4 1.8 0.7 1.2 1.0 -0.8 -1.6 1.3 -0.1 1.0 -0.5 1.2 -1.0
Diastolic blood pressure, automated reading 0.7 2.0 6.8 -0.8 -2.4 -1.6 -1.1 2.3 -0.5 -0.3 2.6 1.3 -1.1 -0.1 -1.2 -0.5 -1.7 0.6
Ever depressed for a whole week 0.5 0.6 3.3 1.6 1.8 0.9 -0.8 -0.1 -0.0 0.4 -0.5 0.7 0.2 -0.2 -0.2 0.5 -0.3 0.2
Unable to work because of sickness or disability 1.7 2.2 9.7 -2.4 -0.2 -3.1 -2.0 0.1 -0.8 -0.3 0.6 0.1 -1.6 0.9 -2.0 -1.0 -1.8 0.4
Commuting to job workplace: Cycle 0.1 0.2 0.6 0.2 0.4 0.6 0.4 0.8 0.2 0.2 -0.4 -0.1 0.7 -0.2 0.4 0.0 0.3 -0.1
Myopia 1.3 1.9 10.4 3.2 0.3 2.5 0.7 1.0 0.5 1.8 -0.1 0.5 0.9 -1.2 1.3 1.3 0.7 -0.4
Vascular/heart problems diagnosed by doctor 3.4 9.3 23.5 1.1 3.2 1.9 4.5 -1.4 3.5 -0.9 -4.9 -3.2 3.6 -1.7 3.8 -1.9 3.9 -2.4
Cholesterol lowering medication 2.1 3.0 7.0 1.3 -2.1 1.8 -0.3 -0.5 -2.0 1.9 2.5 2.0 -1.5 0.9 -1.4 2.6 -1.5 2.0
Medication: Omeprazole (e.g. Zanprol) 1.3 1.6 5.3 -0.1 2.3 0.3 1.7 -0.0 1.6 1.5 -1.2 -1.5 1.5 0.2 1.0 -1.4 1.3 -1.0
Pain experienced in last month 2.0 3.3 8.9 0.4 -1.9 0.9 -0.2 -2.5 -1.5 -1.3 0.7 1.7 -1.9 2.8 -1.7 2.3 -1.9 3.0
Supplements: Calcium 0.2 0.2 0.9 0.5 0.1 0.5 0.5 -0.1 0.1 -0.9 -0.2 0.5 0.1 -0.3 0.0 0.1 -0.4 0.6
Basal cell carcinoma (self-reported) 0.3 0.3 1.3 0.4 0.1 0.1 -0.3 0.3 0.1 0.2 -1.1 -0.4 0.5 -1.0 0.5 -0.1 0.8 -0.9
Heart attack/myocardial infarction (self-reported) 1.3 1.6 3.5 -1.2 1.6 -0.6 0.6 1.5 1.5 1.2 -0.8 -1.9 1.2 -0.7 1.1 -1.2 1.3 -1.8
Deep venous thrombosis (DVT) (self-reported) 0.7 0.9 2.7 -1.2 1.3 -0.6 1.1 1.6 0.6 -0.1 -1.3 -1.1 0.6 -0.2 0.5 -1.2 0.6 -0.7
Heart disease (siblings) 2.9 3.5 8.5 -0.6 -0.5 -1.5 -1.8 -2.9 -1.1 -0.0 1.7 2.0 -2.5 1.9 -2.5 0.3 -2.8 2.4
Alcohol drinker status: Previous 0.9 1.0 2.8 0.3 -0.8 -0.2 -1.4 0.1 -1.3 1.5 1.1 1.7 -0.6 -0.8 -1.3 0.5 -1.4 0.6
Pack years of smoking 0.4 0.6 2.3 -0.1 1.4 0.3 0.9 1.5 0.6 0.1 -1.2 -0.6 0.7 -0.6 0.6 -0.4 0.6 -0.6
Impedance of whole body 0.2 1.2 4.7 0.9 0.5 1.7 1.4 -2.2 0.6 1.5 0.6 -0.8 0.8 1.2 1.0 0.7 0.9 0.3
Leg fat mass (left) 0.5 2.1 4.9 -0.8 -1.4 -1.9 -2.2 1.9 -0.9 0.4 1.8 1.6 -0.7 -0.8 -1.9 -1.0 -2.1 0.2
Arm predicted mass (left) 0.3 1.7 11.2 -0.9 -0.9 -1.8 -1.3 3.4 -0.3 -1.1 -0.6 0.5 -0.1 -1.6 -1.0 -1.3 -0.8 -0.7