Hub : Genes

SERGEF

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1260	0.0330	2.0e-06	0.023	0.068	0.033	0.063	0.033	7.0e-04	1.1e-08	5.5e-05	3.4e-08	6.3e-05
2	GTEx	Adipose Subcutaneous	0.1910	0.0430	1.5e-08	0.170	NA	0.181	NA	0.194	7.5e-14	NA	9.6e-15	NA	9.4e-16
3	GTEx	Adipose Visceral Omentum	0.1540	0.0540	1.4e-03	0.116	NA	0.113	NA	0.013	1.3e-06	NA	1.9e-06	NA	6.7e-02
4	GTEx	Artery Tibial	0.1056	0.0374	8.4e-04	0.073	NA	0.041	NA	-0.003	2.4e-06	NA	3.6e-04	NA	8.2e-01
5	GTEx	Brain Cortex	0.5630	0.0920	1.4e-04	-0.008	NA	0.130	NA	0.150	6.2e-01	NA	1.9e-04	NA	6.4e-05
6	GTEx	Cells Transformed fibroblasts	0.2150	0.0480	3.1e-08	0.153	NA	0.161	NA	-0.003	1.4e-11	NA	3.8e-12	NA	7.9e-01
7	GTEx	Esophagus Mucosa	0.1450	0.0380	3.5e-06	0.199	NA	0.173	NA	0.190	2.4e-13	NA	1.2e-11	NA	9.5e-13
8	GTEx	Esophagus Muscularis	0.1640	0.0620	4.4e-03	0.013	NA	0.108	NA	0.075	5.1e-02	NA	4.5e-07	NA	2.4e-05
9	GTEx	Heart Left Ventricle	0.1916	0.0747	5.7e-03	0.025	NA	0.066	NA	-0.003	1.8e-02	NA	2.2e-04	NA	5.3e-01
10	GTEx	Lung	0.1047	0.0364	4.4e-04	0.079	NA	0.035	NA	0.007	1.2e-06	NA	1.0e-03	NA	9.3e-02
11	GTEx	Muscle Skeletal	0.2606	0.0386	0.0e+00	0.307	NA	0.351	NA	0.343	1.6e-30	NA	9.7e-36	NA	8.4e-35
12	GTEx	Skin Not Sun Exposed Suprapubic	0.2410	0.0570	2.7e-07	0.150	NA	0.146	NA	0.157	1.3e-08	NA	2.2e-08	NA	5.9e-09
13	GTEx	Skin Sun Exposed Lower leg	0.1160	0.0340	2.0e-05	0.075	NA	0.064	NA	0.067	8.8e-07	NA	4.8e-06	NA	3.1e-06
14	METSIM	Adipose	0.0936	0.0241	5.6e-09	0.103	0.068	0.087	0.091	0.102	3.4e-15	2.0e-10	5.1e-13	1.8e-13	5.1e-15
15	YFS	Blood	0.1050	0.0197	0.0e+00	0.040	0.069	0.084	0.080	0.083	4.7e-13	1.9e-21	5.1e-26	9.7e-25	7.8e-26
16	TCGA	Breast Invasive Carcinoma	0.0315	0.0158	1.7e-03	0.008	0.003	0.005	NA	0.007	8.4e-03	7.6e-02	2.3e-02	NA	1.1e-02
17	TCGA	Head and Neck Squamous Cell Carcinoma	0.0526	0.0233	2.5e-04	0.004	0.030	0.023	NA	0.016	9.8e-02	2.1e-04	1.0e-03	NA	5.5e-03
18	TCGA	Brain Lower Grade Glioma	0.0740	0.0277	4.5e-06	0.087	0.054	0.080	NA	0.083	3.9e-10	9.0e-07	2.3e-09	NA	9.6e-10
19	TCGA	Lung Adenocarcinoma	0.0353	0.0203	4.2e-03	0.003	0.007	0.000	NA	-0.002	1.1e-01	4.1e-02	2.8e-01	NA	9.9e-01
20	TCGA	Lung Squamous Cell Carcinoma	0.0241	0.0131	7.5e-03	0.000	0.014	0.003	NA	0.003	2.9e-01	8.5e-03	1.2e-01	NA	1.3e-01
21	TCGA	Prostate Adenocarcinoma	0.0561	0.0272	3.9e-04	0.002	0.015	0.003	NA	0.004	1.9e-01	9.2e-03	1.5e-01	NA	1.2e-01

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21
Bipolar Disorder (2018)	2.8	4.5	9.4	0.1	-2.8	-2.6	-1.9	0.4	-2.4	-2.4	-3.1	-2.5	-2.3	-2.8	-3.0	-2.3	-2.2	1.5	-0.8	-1.6	1.3	-1.0	-2.6	-1.2
Bipolar Disorder or Schizophrenia	4.1	9.9	20.0	0.3	-3.4	-3.5	-3.0	1.5	-3.4	-3.4	-2.7	-4.1	-3.4	-4.1	-3.8	-3.5	-3.3	2.7	0.1	-3.2	2.2	-3.3	-4.5	-2.6
Depressed Affect (Nagel 2018)	1.0	2.0	4.7	2.1	1.4	1.8	1.9	-1.7	1.5	1.4	-0.2	0.7	1.2	1.2	1.3	1.6	1.2	0.1	1.3	2.0	-0.6	0.6	1.5	2.2
Depression (Nagel 2018)	0.9	1.4	3.3	1.1	1.3	1.3	1.5	-0.4	1.2	1.3	0.2	0.5	1.0	1.1	1.2	1.6	1.3	-0.3	0.4	1.8	-0.6	1.0	1.7	1.7
Intelligence (Savage-Jansen 2018)	1.5	4.5	11.0	0.4	1.8	2.5	1.8	-2.2	2.7	2.3	2.2	3.3	3.0	2.6	1.8	2.7	2.5	-2.0	-0.1	1.9	0.1	1.0	2.8	0.2
Neuroticism (Nagel 2018)	1.4	3.2	9.7	1.9	1.6	1.7	1.9	-2.6	1.8	1.4	0.9	1.5	1.0	1.4	1.6	1.6	1.3	0.5	2.2	3.1	-0.6	1.0	2.0	3.0
Schizophrenia (2018)	2.8	5.9	13.5	0.3	-2.1	-2.5	-2.3	1.6	-2.3	-2.5	-1.0	-3.3	-2.4	-3.0	-2.4	-2.6	-2.5	2.2	0.8	-2.9	1.8	-3.4	-3.7	-2.4
Schizophrenia vs Biploar Disorder	1.1	1.4	2.9	0.9	1.7	1.5	0.7	-1.1	1.2	1.4	1.4	1.0	1.7	1.4	1.5	1.6	1.3	-0.1	0.4	1.0	-0.6	0.7	1.0	0.8
Worry (Nagel 2018)	0.6	1.2	6.9	0.4	0.5	-0.1	0.6	-2.2	0.6	0.2	0.8	1.0	-0.3	-0.0	0.0	0.6	0.2	1.2	1.2	2.6	-0.5	0.7	0.9	2.5
Alzheimer’s Disease (in mother)	0.5	0.6	2.3	-0.4	1.2	0.4	-0.6	0.1	0.4	0.8	1.4	0.1	0.8	0.2	0.8	0.5	0.8	-0.3	0.9	-0.0	-1.5	-0.9	-0.3	0.7
Alzheimer’s Disease (in father)	0.8	0.9	4.1	-0.8	-0.7	-0.6	-0.8	0.8	-1.0	-0.6	-0.2	-0.3	-0.5	-0.8	-0.6	-0.8	-0.7	-0.8	-0.6	-1.3	0.9	-2.0	-1.1	-1.7
Alzheimer’s Disease (including proxy)	0.2	0.3	1.3	-0.4	0.7	0.2	-0.7	0.0	0.0	0.5	0.6	-0.5	0.5	-0.1	0.5	0.1	0.4	-0.3	0.8	-0.6	-0.3	-1.1	-0.7	-0.2
Crohns Disease (2017)	0.7	1.5	6.2	2.2	-0.9	-1.2	-0.3	0.5	-1.0	-1.1	0.8	-1.3	-0.7	-1.5	-1.0	-1.1	-1.0	1.7	1.3	0.7	2.5	-1.5	-0.7	-0.8
Irritable Bowel Disease (IBD)	0.6	1.4	4.9	1.2	-1.2	-1.1	-0.0	0.6	-0.9	-1.4	0.3	-0.7	-0.8	-1.6	-1.4	-1.4	-1.3	1.1	0.8	-0.0	2.2	-1.7	-1.2	-0.9
Ulcerative Colitis (UC)	0.8	1.4	2.9	-0.5	-1.5	-1.2	-0.5	0.7	-1.0	-1.6	-0.5	-0.4	-1.1	-1.7	-1.5	-1.7	-1.7	0.6	-0.1	-1.1	1.0	-1.7	-1.7	-1.0
Major Depression (MDD)	0.6	0.7	5.0	0.4	0.7	0.6	0.9	-0.9	0.1	0.6	2.2	0.4	0.9	0.6	0.7	1.1	0.7	0.0	-0.0	0.8	-1.0	-0.6	1.3	-0.4
Reaction Time	3.5	6.7	14.1	-0.9	-2.5	-3.8	-1.7	0.5	-3.5	-3.0	1.2	-1.4	-2.3	-3.6	-2.3	-3.0	-3.0	2.2	0.6	-2.4	1.8	-3.8	-3.6	-2.8
Verbal and Numeric Reasoning (VNR)	0.7	1.7	5.1	-0.2	1.2	1.5	0.9	-2.3	1.6	1.2	1.3	2.0	1.1	1.4	1.1	1.5	1.3	-1.9	-0.4	1.1	-0.4	0.7	1.5	0.3
Breast Cancer	0.4	0.9	3.9	-2.0	0.7	-0.2	-0.1	-0.4	0.7	0.6	1.4	1.6	0.4	0.6	0.9	1.1	0.7	-0.3	-1.5	1.0	-1.3	0.7	1.2	0.2
Ovarian Cancer	2.3	3.0	6.6	-0.8	-2.2	-1.9	-1.9	-0.7	-2.6	-2.4	-0.4	-2.6	-1.6	-1.9	-2.3	-2.0	-2.4	0.2	-1.1	-1.0	0.2	-2.2	-1.2	-1.1
Prostate Cancer	1.9	2.7	6.1	-0.7	2.0	1.3	1.3	0.8	1.9	1.7	1.6	1.7	1.5	1.6	2.3	1.5	1.5	-0.8	1.0	2.1	-1.8	1.6	1.8	2.5
Age at First Birth	0.7	1.0	4.7	0.3	-0.7	-0.5	-1.2	0.1	-0.3	-0.6	-1.2	-0.0	-0.5	-0.7	-0.4	-1.1	-0.5	2.2	1.8	-0.9	2.1	0.1	-1.5	-0.4
Bipolar Disorder (2011)	2.4	2.3	5.3	-0.1	-1.7	-1.8	-1.5	-0.7	-1.5	-1.7	-0.3	-2.1	-2.3	-1.9	-2.0	-1.8	-1.7	1.1	-0.9	-1.5	-0.2	-1.8	-1.8	-0.9
Body Mass Index (BMI) (2010)	0.5	0.7	2.2	1.5	0.8	0.7	0.8	-0.4	0.2	0.8	0.1	0.0	0.9	0.8	1.1	1.0	0.8	-0.1	-0.0	1.2	-0.7	1.1	1.1	1.3
Coronary Artery Disease (CAD)	0.4	0.4	2.5	-1.6	0.7	0.3	-0.2	0.3	0.3	0.4	0.7	0.1	0.4	0.3	0.2	0.4	0.4	-0.1	-0.9	0.7	-0.4	1.3	0.6	1.3
Crohns Disease (2012)	0.5	0.9	1.8	0.8	-1.0	-1.1	-0.9	-0.2	-1.3	-1.1	0.7	-0.7	-0.7	-1.3	-1.3	-0.7	-1.0	1.3	-0.6	0.7	0.9	-0.9	-0.1	-0.8
Mean Putamen Volume	1.5	1.7	7.1	-0.8	-1.4	-1.2	-0.9	2.7	-0.7	-1.3	0.7	0.6	-0.9	-1.0	-1.4	-1.5	-1.3	0.8	1.3	-0.9	2.1	-1.3	-1.1	-1.4
Fasting Glucose	1.8	2.2	12.9	3.6	0.4	1.6	1.1	-1.4	1.2	-0.1	1.5	1.6	0.2	1.2	2.0	0.1	-0.4	0.4	2.0	2.2	0.5	1.0	1.9	1.3
HbA1C	1.9	2.1	5.3	1.4	1.7	1.7	1.0	-1.4	1.3	2.2	-0.2	1.6	2.0	1.4	0.9	2.2	2.3	-0.8	0.4	0.5	-0.3	1.8	0.8	1.0
HDL Cholesterol	0.6	1.0	2.3	-0.8	-0.8	-1.5	-0.9	0.0	-0.7	-1.1	0.0	-1.5	-1.2	-1.4	-0.8	-1.0	-1.0	-0.5	-0.1	-1.2	0.2	-1.2	-1.4	-0.8
LDL Cholesterol	1.6	2.5	10.9	2.8	-1.6	-0.6	-1.0	-0.9	-1.3	-1.4	0.0	-0.5	-0.8	-1.3	-1.3	-1.4	-1.3	2.5	2.1	0.3	3.3	-2.2	-1.0	-1.1
Lupus	0.8	1.3	4.5	1.5	1.0	1.4	1.0	-2.1	1.0	0.9	0.1	1.8	0.5	0.9	0.9	0.7	0.9	0.7	2.1	0.6	0.4	0.7	0.4	1.3
Neuroticism (2016)	2.8	4.0	6.6	2.6	2.0	2.0	1.7	-2.3	2.2	2.2	0.7	2.4	2.0	2.1	2.2	2.2	2.2	0.1	1.1	2.5	-0.5	2.0	2.1	2.4
Primary Biliary Cirrhosis	1.9	2.7	6.5	0.6	-1.9	-1.8	-1.9	0.2	-1.1	-1.7	-0.7	-0.8	-2.0	-1.7	-2.5	-1.9	-1.6	0.4	0.3	-1.8	2.4	-1.7	-1.8	-2.1
Rheumatoid Arthritis	0.4	0.5	1.4	-0.1	-0.9	-0.5	-0.5	0.5	-0.7	-0.7	-0.9	-0.8	-0.5	-0.7	-0.4	-1.2	-0.7	0.2	0.9	-0.7	1.0	-0.5	-0.8	-0.4
Schizophrenia (2014)	1.7	3.8	10.4	0.8	-1.9	-1.9	-1.8	0.6	-2.0	-2.0	-1.2	-2.3	-1.9	-2.4	-2.1	-2.3	-2.1	1.6	0.5	-2.7	1.4	-2.5	-3.2	-1.6
Triglycerides	2.7	4.4	9.0	0.6	2.6	3.0	1.7	-0.4	2.5	2.7	2.1	2.9	3.0	2.8	2.5	2.1	2.6	-0.9	0.6	1.2	-1.3	1.9	2.1	1.1
Type 2 Diabetes (T2D) (2012)	0.7	0.9	5.5	1.5	0.7	0.7	0.3	-0.8	1.3	0.7	2.3	0.2	0.4	0.7	0.3	1.0	0.6	1.2	1.0	1.0	-0.0	0.1	0.8	-0.3
Ulcerative Colitis	0.1	0.2	0.5	-0.7	-0.4	-0.1	-0.1	0.7	-0.2	-0.5	0.5	0.3	-0.1	-0.4	-0.7	-0.5	-0.5	-0.1	-0.1	0.0	0.2	-0.7	-0.2	-0.0
Blood Eosinophil Count	0.7	5.4	15.0	2.0	2.2	2.6	1.6	-3.9	2.1	2.4	1.1	1.9	2.7	2.7	2.8	2.9	2.6	-2.2	-0.3	2.6	-0.2	1.6	3.2	1.1
Blood Platelet Count	1.1	12.8	22.8	-0.7	4.4	3.5	3.3	-2.7	3.0	3.9	3.2	3.2	3.6	4.2	4.4	4.3	3.8	-3.7	-2.0	3.3	-4.8	3.4	4.6	3.0
Blood Red Count	0.2	2.4	8.2	2.9	1.2	1.7	1.0	-0.8	1.4	1.6	0.4	1.6	2.1	1.7	2.1	1.2	1.6	-0.8	-0.1	1.4	-0.2	2.4	1.8	1.1
Blood White Count	2.6	19.2	30.6	0.7	5.5	4.7	3.9	-3.4	4.8	5.2	3.4	3.9	4.0	5.1	4.9	5.3	5.0	-2.7	-0.4	4.4	-4.4	5.3	5.2	5.3
Heel T-Score	0.4	2.9	9.0	-1.3	1.5	1.8	1.1	2.6	2.0	1.4	2.4	1.8	1.3	1.7	1.3	1.3	1.2	-1.9	-1.8	0.3	-3.0	1.1	1.6	1.1
BMI	1.3	7.6	16.2	3.5	2.4	3.1	1.8	-2.7	2.4	3.0	2.8	2.2	3.9	3.1	3.5	3.3	3.1	-2.0	-0.0	3.1	-0.1	2.5	4.0	0.1
Height	1.6	31.3	49.6	0.4	-7.0	-6.7	-4.9	2.6	-5.1	-6.6	-5.1	-6.5	-6.4	-6.8	-5.9	-6.3	-6.4	4.1	1.0	-5.2	5.9	-5.4	-6.6	-6.1
Waist Hip Ratio (WHR)	0.2	1.0	3.1	0.3	1.1	1.2	0.7	-0.8	1.5	1.1	0.2	1.8	0.8	1.3	0.8	0.7	1.1	-1.5	0.1	-0.6	-1.1	0.8	0.2	0.4
Systolic Blood Pressure	0.2	1.2	5.8	-2.4	0.6	-0.1	-0.1	-0.0	0.7	0.4	1.1	-0.0	0.2	0.5	0.2	0.4	0.4	-1.6	-2.3	0.7	-2.2	1.2	1.0	0.7
Smoking Status	1.3	3.2	7.4	-2.0	2.0	1.5	1.7	-1.0	1.7	1.9	1.7	1.8	1.5	2.0	1.0	2.2	1.8	-2.0	-1.1	1.8	-2.3	1.8	2.7	1.4
Allergy or Eczema	0.4	1.1	2.6	0.0	0.3	1.3	1.2	-0.5	1.2	0.9	-0.3	1.6	1.4	1.1	0.7	1.2	1.2	-1.3	-0.4	0.7	1.4	1.3	1.2	-0.2
Cardiovascular Disease	0.9	2.9	8.2	0.1	2.0	1.9	0.2	-1.2	1.7	1.9	0.4	0.7	1.9	1.9	1.9	1.8	1.9	-2.9	-0.3	1.4	-2.4	1.8	1.8	2.2
Hypothyroidism (self reported)	0.2	0.5	3.6	0.7	-0.3	-0.4	-0.3	-0.5	-0.6	-0.3	-1.9	-1.6	-0.0	-0.3	-0.5	0.0	-0.1	0.7	0.4	0.3	0.6	0.8	0.1	-0.2
Respiratory disease	1.1	2.5	8.2	-0.1	1.4	2.1	1.1	-0.8	1.4	1.5	-1.1	1.6	1.4	1.9	1.7	1.6	1.4	-1.9	-1.6	0.7	-1.8	2.9	1.9	1.6
Type 2 Diabetes (T2D) (2018)	1.3	2.4	4.7	0.3	2.2	1.5	0.8	1.7	2.1	1.9	2.1	1.3	2.1	1.8	1.8	1.6	1.9	-0.7	2.0	0.9	-0.3	0.4	1.3	0.9
Lung FEV1/FVC ratio	0.2	1.1	8.6	0.7	1.0	0.3	-0.4	0.2	0.5	0.4	2.0	0.6	-0.4	0.3	0.6	-0.1	0.2	2.1	2.9	0.2	-0.3	-1.3	-0.2	0.7
Lung FVC	0.1	0.5	2.5	0.2	-0.4	0.2	-0.5	0.8	-0.1	-0.1	-1.0	-0.3	0.4	-0.1	0.5	-1.0	-0.0	-0.8	0.3	-1.6	1.1	-1.2	-1.3	-0.6
Neuroticism	1.8	4.4	13.6	2.4	1.9	2.1	2.0	-1.8	2.2	1.8	1.1	1.9	1.5	1.7	2.0	2.0	1.7	0.6	2.7	3.7	-0.5	1.7	2.3	3.6
Chronotype (morning person)	0.3	0.6	2.7	1.1	0.1	-0.3	-0.0	-1.2	0.6	0.2	-0.5	-0.8	0.2	0.1	0.9	0.2	0.3	1.4	1.6	0.6	1.1	0.9	0.0	0.6
Hair Pigment	0.1	4.0	8.0	0.7	2.3	1.9	1.6	-2.7	1.4	2.0	0.9	0.1	2.0	2.1	2.5	2.1	2.0	-2.2	-0.5	2.0	-2.5	2.8	2.4	2.5
Tanning	0.1	0.6	5.6	0.2	0.4	0.2	0.6	0.7	0.3	0.4	-2.4	0.1	-0.6	0.3	0.2	0.5	0.3	-0.5	-0.6	0.5	-0.5	1.3	-0.1	1.5
Hand grip strength (left)	0.1	0.2	1.1	0.1	-0.4	0.3	-0.6	1.1	0.5	-0.3	-0.4	0.3	-0.6	0.2	-0.4	-0.4	-0.3	-0.6	-0.5	-0.5	-0.0	0.8	0.1	0.3
Number of treatments/medications taken	1.2	2.2	6.2	0.7	2.5	1.7	1.0	-1.0	1.8	2.1	1.5	1.5	1.3	2.0	1.9	1.6	1.9	0.6	1.1	0.7	-0.6	1.6	1.1	1.2
Average weekly spirits intake	1.3	1.7	4.8	0.5	1.3	1.1	1.2	-1.5	1.6	1.3	0.8	-0.3	0.8	1.5	1.0	2.1	1.4	0.1	0.5	2.2	-0.1	1.5	2.1	0.8
Sensitivity / hurt feelings	3.2	5.4	15.9	0.2	2.7	2.3	2.6	-1.2	2.3	2.3	0.6	1.8	2.0	2.5	2.4	2.4	2.1	-0.5	1.1	3.0	-3.0	3.0	3.0	4.0
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.9	0.7	0.8	0.5	1.2	0.2	0.5	0.8	-0.3	0.4	0.3	0.6	0.7	0.9	0.8	0.1	0.1	0.8	-1.4	0.4	0.7	1.4
Hearing difficulty/problems: Yes	2.4	3.7	9.0	0.7	1.5	1.9	2.9	-0.8	2.1	2.0	-0.6	1.1	2.5	2.1	2.0	2.4	2.2	-3.0	-1.2	1.7	-0.9	2.2	2.5	1.2
Relative age of first facial hair	0.6	1.3	3.7	-1.6	-1.4	-1.0	-1.0	0.6	-1.0	-1.2	-1.4	0.4	-1.1	-1.1	-1.4	-1.2	-1.0	-0.5	-1.9	-1.6	-0.1	-0.4	-1.0	-0.8
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	2.0	-0.0	-0.1	-0.4	0.4	1.0	-0.3	-0.1	-1.4	0.3	-0.2	-0.2	-0.1	0.4	-0.1	0.6	-0.4	-0.0	-0.2	0.6	0.1	-0.1
Ever used hormone-replacement therapy (HRT)	6.7	8.5	15.4	2.3	3.5	3.6	3.1	-1.8	3.1	3.4	2.3	3.9	3.4	3.6	3.8	3.4	3.3	-1.0	2.4	2.4	-0.9	2.1	3.1	2.3
Ever had hysterectomy (womb removed)	3.3	3.7	6.3	1.1	2.4	2.1	1.8	-0.5	2.3	2.5	0.4	1.5	2.2	2.4	2.5	1.9	2.3	-1.8	0.4	1.6	-1.7	2.4	1.9	2.5
Systolic blood pressure, automated reading	1.0	2.8	6.7	-1.1	1.7	1.2	1.3	-1.3	1.5	1.5	2.4	0.8	1.5	1.7	1.8	1.8	1.4	-1.7	-1.3	2.2	-2.0	2.0	2.6	1.3
Eye problems/disorders: Diabetes related eye disease	2.2	2.4	4.6	-0.5	1.8	2.0	1.6	0.6	1.5	1.7	0.3	1.2	1.6	2.0	1.5	1.7	1.7	-1.5	0.5	1.9	-1.4	1.7	2.1	1.9
Angina	3.7	4.8	9.5	0.4	2.6	1.9	1.5	-2.2	2.2	2.5	2.1	2.3	2.1	2.4	2.2	2.9	2.5	-1.6	-0.5	2.7	-2.3	2.0	3.1	2.3
Medication for hormone replacement therapy	0.7	0.8	3.5	0.9	1.0	1.1	-0.2	-0.6	1.0	1.0	0.7	0.7	0.7	1.0	1.0	0.3	0.9	-0.5	1.1	-1.9	0.7	-0.5	-0.9	-0.9
Vitamin and mineral supplements	0.2	0.2	1.6	0.7	0.0	-0.1	-0.5	0.9	0.4	0.0	-0.1	-0.9	-0.1	0.1	-0.3	0.1	-0.1	1.3	-0.2	0.3	0.0	-0.1	0.3	0.2
Supplements: Zinc	1.1	1.1	5.4	-1.0	1.0	0.9	0.9	-1.1	0.3	0.9	-0.4	1.1	0.5	1.2	0.9	0.9	0.8	-2.1	-1.3	-0.3	-2.3	0.4	0.7	0.8
Medication: Co-codamol	0.8	1.0	2.0	-0.4	1.2	1.2	0.3	0.1	1.1	1.3	1.3	1.0	1.3	1.4	1.2	1.2	1.3	0.7	0.3	0.1	-0.1	1.4	1.0	0.1
Medication: Metformin	0.6	0.8	6.1	-0.4	1.1	0.7	0.4	2.5	0.7	0.8	1.4	0.7	1.0	0.6	0.8	0.5	0.9	-0.6	1.3	0.2	-0.6	-0.5	0.3	0.4
Diabetes (father)	0.9	1.1	3.6	1.9	-0.8	-1.2	-0.7	-0.7	-0.7	-1.0	1.1	-0.5	-0.5	-1.3	-0.3	-0.5	-0.8	1.9	0.9	1.3	1.4	-1.4	-0.2	-0.3
Diabetes (mother)	0.4	0.5	3.3	-0.4	-0.8	-0.7	-0.7	-0.1	-0.6	-0.6	-0.7	0.1	-0.4	-0.5	-0.8	-0.1	-0.5	-0.9	-1.8	0.6	0.7	0.7	0.3	-0.2
Severe depression (siblings)	0.2	0.2	1.0	-0.7	-0.2	0.3	-0.3	0.1	0.1	0.0	-1.0	0.3	0.2	-0.1	-0.1	0.6	0.1	0.6	-0.2	-0.2	0.8	0.3	0.1	-0.4
Pack years adult smoking proportion	0.5	0.8	4.6	-1.1	-0.0	-0.4	0.5	-1.2	0.1	-0.2	-2.1	-0.7	-0.7	-0.6	-0.6	0.5	-0.1	0.5	-1.1	0.5	-0.5	1.7	0.2	1.1
Impedance of leg (right)	0.1	0.5	3.0	-0.5	0.2	-0.3	-0.6	1.7	0.4	0.0	0.1	1.1	-0.6	0.0	-0.8	-0.5	0.0	0.7	0.6	-1.0	-0.4	-0.4	-1.0	0.8
Leg fat-free mass (left)	0.8	4.1	8.8	0.6	-3.0	-2.3	-2.0	-0.5	-2.2	-2.6	-1.9	-2.8	-1.8	-2.7	-1.6	-2.0	-2.4	1.1	-0.3	-1.2	2.4	-1.7	-1.8	-2.9
Trunk fat percentage	1.4	5.4	12.7	0.2	2.7	2.2	1.1	-3.6	2.0	2.6	2.9	1.9	3.1	2.4	3.2	2.8	2.6	-1.6	-0.4	2.4	-2.1	1.4	2.9	1.5
Hand grip strength (right)	0.2	0.6	3.8	0.8	-0.0	0.6	-0.1	1.3	0.9	0.3	-1.6	0.1	0.0	0.5	0.1	0.3	0.3	-0.8	-0.5	0.4	0.2	1.9	0.8	1.1
Townsend deprivation index at recruitment	0.3	0.5	3.3	0.3	-0.6	-0.4	-0.3	-1.8	-0.3	-0.3	-0.4	0.3	-0.4	-0.0	-1.0	0.2	-0.2	-0.7	-1.2	0.5	0.0	-0.5	0.8	-1.0
Current tobacco smoking	1.3	2.1	4.0	-1.8	1.8	1.4	1.6	-0.5	1.4	1.7	0.6	0.4	0.9	1.7	0.5	1.6	1.6	-1.7	-0.4	1.2	-1.6	2.0	1.9	1.8
Average weekly fortified wine intake	0.5	0.6	2.5	0.2	0.1	0.6	1.2	-0.6	0.6	0.1	0.6	1.6	0.7	0.3	0.1	0.3	0.2	1.4	1.0	0.4	1.6	0.0	0.3	-0.5
Maternal smoking around birth	2.6	3.7	13.5	-1.2	2.3	2.1	1.7	1.8	1.7	2.1	0.6	0.2	1.5	2.2	1.5	2.5	1.9	-1.7	-0.9	1.6	-3.7	2.1	2.7	1.7
Fed-up feelings	1.0	1.7	7.0	2.3	1.0	1.3	1.1	-2.6	1.3	1.2	-0.4	0.5	0.9	1.1	1.3	1.4	1.1	-0.2	0.9	1.8	-0.4	0.7	1.4	1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	2.8	0.4	0.9	0.5	0.7	-0.0	1.0	1.0	-0.9	-0.1	0.6	0.6	0.6	1.4	1.0	0.8	0.1	1.5	-0.7	1.6	1.3	1.7
Relative age voice broke	0.4	0.7	4.2	-1.9	0.0	0.5	0.2	-0.1	0.2	0.2	-0.4	0.6	0.5	0.1	-0.1	0.3	0.3	-1.4	-2.0	-0.3	-1.6	0.1	0.4	0.1
Taking other prescription medications	2.6	4.1	9.0	1.7	3.0	2.3	1.6	-1.4	2.2	2.6	1.2	2.0	2.3	2.3	2.4	2.3	2.5	0.1	1.8	1.3	-1.2	1.9	1.5	2.5
Age when periods started (menarche)	2.0	4.8	10.2	-0.3	-2.7	-2.4	-2.7	1.5	-2.6	-2.5	-1.6	-2.6	-2.7	-2.7	-3.2	-2.6	-2.6	0.5	-2.1	-1.2	1.3	-1.8	-1.9	-1.4
Bilateral oophorectomy (both ovaries removed)	12.6	14.5	24.7	1.3	4.3	4.4	4.1	-2.4	5.0	4.5	1.6	4.2	4.1	4.8	4.6	4.2	4.5	-2.6	1.6	3.5	-2.2	4.4	4.3	3.9
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	2.2	-0.5	0.4	0.2	-0.9	0.8	0.2	0.1	0.9	0.4	-0.0	-0.0	-0.0	-0.5	-0.0	-1.0	-1.4	-1.5	-1.5	-0.6	-0.7	-0.1
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	3.9	0.1	0.6	0.3	0.7	0.8	0.3	0.9	-2.0	0.3	1.1	0.6	0.9	0.8	1.0	-1.1	-0.9	-0.3	-0.3	1.4	0.1	0.7
Qualifications: CSEs or equivalent	1.1	1.4	8.2	-1.2	1.0	0.5	0.5	0.4	-0.0	0.8	0.0	-0.3	0.7	0.8	0.5	1.1	0.9	-0.8	-0.9	2.1	-2.9	1.4	1.8	1.8
Serious illness, injury or assault to yourself	0.4	0.4	1.3	1.1	0.6	-0.1	-0.4	0.2	0.9	0.8	-0.5	1.1	0.1	0.4	0.8	0.6	0.9	0.3	1.1	-0.5	0.9	0.5	-0.3	0.1
High blood pressure	0.9	2.4	5.7	-0.7	1.9	1.4	1.0	-1.0	1.6	1.8	0.5	0.8	1.4	1.7	1.9	1.5	1.7	-2.1	0.1	1.3	-2.4	1.5	1.6	2.2
Hayfever, allergic rhinitis or eczema	1.1	2.4	4.8	1.1	1.0	2.2	2.0	-0.7	1.8	1.7	-0.5	1.8	2.2	1.8	1.4	1.9	2.0	-1.9	-0.3	0.9	1.2	1.7	1.7	0.1
Multivitamins +/- minerals	0.3	0.4	3.4	-0.9	0.3	0.4	0.9	-1.0	0.2	0.4	-0.3	1.2	0.4	0.3	0.7	0.3	0.6	-1.8	0.1	-0.3	-0.3	0.2	0.0	-0.1
Stomach or abdominal pain in last month	0.3	0.3	0.7	0.8	-0.2	-0.5	-0.9	0.3	-0.6	-0.2	-0.8	-0.8	-0.7	-0.4	-0.5	-0.5	-0.3	0.6	0.5	-0.7	-0.5	-0.3	-0.7	0.4
Supplements: Glucosamine	2.6	3.4	7.7	-0.6	2.4	2.3	1.0	-0.1	1.7	2.4	0.6	1.6	2.5	2.4	2.4	2.1	2.3	-2.8	-1.0	0.4	-1.6	2.3	1.6	1.3
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	2.1	0.8	-0.1	0.5	-0.1	1.4	0.7	0.0	-1.2	-0.5	-0.2	0.3	0.2	0.0	-0.1	0.2	0.9	0.7	0.6	1.0	0.5	1.0
Medication: Atenolol	0.4	0.5	1.6	0.4	0.6	0.6	0.9	-1.0	0.3	0.5	-0.5	-0.9	0.3	0.5	0.3	0.5	0.5	-0.4	-0.4	1.0	-1.0	0.6	0.7	1.3
Medication: Levothyroxine sodium	0.2	0.4	1.8	0.2	-0.0	0.4	0.2	-1.3	0.4	0.3	-1.2	-0.1	0.7	0.4	-0.0	0.6	0.5	0.1	0.1	0.8	0.4	1.0	0.9	-0.2
Sitting height	3.5	24.6	41.1	-0.1	-6.2	-5.8	-4.3	2.7	-5.3	-5.9	-3.8	-5.4	-5.2	-6.4	-5.2	-5.6	-5.7	3.6	0.8	-4.2	5.2	-5.5	-5.9	-5.4
Chronic bronchitis/emphysema (father)	1.0	1.2	6.2	0.6	1.0	1.0	0.9	-0.9	0.6	1.0	1.1	0.7	0.6	1.0	0.7	1.1	1.0	0.1	0.7	2.5	-0.5	0.9	2.1	1.4
High blood pressure (mother)	4.6	6.4	12.1	-1.0	-3.5	-3.4	-3.2	-0.2	-2.8	-3.4	-3.0	-2.3	-3.2	-3.5	-2.9	-2.4	-3.1	1.4	-2.7	-1.3	1.3	-0.7	-2.1	-1.5
Body mass index (BMI)	1.6	6.9	14.4	1.4	2.6	2.9	1.6	-3.6	2.2	2.8	2.4	1.9	3.5	2.8	3.6	3.3	2.8	-1.9	-0.5	3.1	-1.7	2.4	3.8	1.3
Impedance of leg (left)	0.1	0.3	1.2	-0.5	0.5	-0.1	-0.3	1.1	0.5	0.3	0.2	1.1	-0.3	0.3	-0.5	-0.0	0.4	0.5	0.3	-0.2	-0.3	0.0	-0.3	1.0
Leg predicted mass (left)	0.8	4.1	8.7	0.7	-2.9	-2.3	-1.9	-0.6	-2.2	-2.6	-1.8	-2.7	-1.8	-2.7	-1.6	-2.0	-2.4	1.1	-0.2	-1.2	2.4	-1.8	-1.7	-2.9
Trunk fat mass	0.5	2.1	10.6	0.5	1.4	1.1	0.2	-3.3	1.0	1.4	1.9	0.8	2.0	1.1	2.1	1.7	1.4	-0.9	-0.4	1.5	-1.1	0.5	1.8	0.3
Waist circumference	0.7	2.6	7.5	0.9	1.4	1.5	0.7	-2.7	1.3	1.6	1.3	1.1	2.1	1.7	2.3	2.1	1.7	-1.8	-0.5	1.7	-1.0	1.0	2.4	-0.2
Number of incorrect matches in round	0.6	0.9	4.5	-0.7	1.3	0.8	0.7	0.9	0.7	0.9	0.2	-0.2	0.6	1.0	1.5	0.7	0.7	-1.4	0.5	-0.6	-2.1	0.8	-0.0	1.1
Past tobacco smoking	1.1	2.1	5.6	0.3	-1.1	-1.5	-1.1	1.1	-1.4	-1.2	-2.0	-2.3	-1.4	-1.6	-0.6	-1.6	-1.2	2.2	0.9	-1.7	1.5	-0.8	-2.4	-0.3
Alcohol usually taken with meals	2.1	3.4	7.7	0.2	-1.9	-2.1	-1.6	1.3	-2.0	-2.0	0.4	-0.9	-1.5	-1.9	-1.7	-2.0	-2.0	1.7	-0.0	-2.7	1.4	-2.8	-2.4	-2.7
Nervous feelings	0.6	1.1	3.3	-0.9	-0.9	-1.8	-1.0	-0.4	-1.1	-1.3	0.8	-0.1	-1.7	-1.4	-1.1	-0.9	-1.3	0.9	-0.4	1.4	-0.8	-0.5	-0.1	1.2
Frequency of tenseness / restlessness in last 2 weeks	1.6	2.5	7.2	0.1	1.3	1.3	1.0	-0.7	1.8	1.5	-0.9	1.5	1.2	1.5	1.4	1.8	1.6	-0.9	-0.3	2.3	-2.0	2.2	2.3	2.7
Hearing difficulty/problems with background noise	0.6	1.0	2.6	0.6	1.0	0.3	1.6	-0.5	1.1	1.1	0.6	1.2	1.5	1.0	1.4	1.1	1.3	-1.4	-0.2	0.8	-0.2	0.4	1.0	0.1
Hair/balding pattern: Pattern 2	0.6	0.7	4.9	0.2	-0.3	-0.2	0.5	-0.5	-0.7	-0.3	-2.1	-0.5	-0.5	-0.7	-0.5	-0.4	-0.3	2.2	-0.0	0.0	0.1	1.0	-0.7	1.2
Had menopause	4.8	6.0	11.5	0.8	3.4	2.9	2.2	0.1	2.9	3.0	2.8	2.8	3.0	2.9	3.3	2.7	2.8	-0.2	2.1	2.1	-1.0	2.0	2.4	2.3
Had other major operations	1.5	1.8	4.7	-0.1	2.2	1.4	0.9	1.5	1.0	1.9	0.1	1.0	1.6	1.5	2.0	1.7	1.9	-0.7	0.9	0.6	-1.3	1.6	0.8	1.3
Forced vital capacity (FVC)	1.6	6.1	12.2	0.7	-3.4	-2.3	-2.0	1.6	-2.2	-2.9	-3.5	-2.4	-2.3	-2.8	-2.5	-3.1	-2.7	0.8	-0.2	-2.9	2.7	-2.1	-3.3	-2.4
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	3.0	-0.3	0.6	0.5	-0.8	1.5	0.5	0.3	0.6	0.7	0.2	0.3	0.4	-0.4	0.2	-1.1	-1.4	-1.7	-1.5	-0.0	-0.8	-0.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.7	2.8	1.7	-0.6	-0.5	-0.1	-1.4	0.1	-0.4	-0.3	-0.4	-0.5	-0.4	-0.9	0.2	-0.2	1.1	1.0	0.6	1.4	-1.1	0.1	-0.9
Qualifications: None of the above	0.4	0.9	2.7	-0.6	1.0	0.6	0.3	0.6	0.8	1.0	0.3	-0.1	0.5	0.9	0.7	0.9	0.9	-1.2	-0.4	1.6	-0.6	1.5	1.4	1.6
Financial difficulties in last 2 years	0.5	0.7	2.6	0.9	0.4	0.8	0.7	-1.6	0.7	0.6	0.8	0.3	0.6	1.0	0.3	0.7	0.7	-0.9	0.4	1.3	0.2	0.5	1.6	-0.3
Mouth/teeth dental problems	0.3	0.5	3.0	-0.0	0.2	0.6	-0.4	-0.4	0.2	0.5	-1.2	1.7	0.4	0.4	0.4	0.2	0.6	0.0	1.1	0.2	0.8	0.8	0.1	0.9
Heart attack	2.1	2.7	5.9	1.7	2.0	1.8	1.7	-1.5	1.0	1.8	2.4	1.8	1.9	1.6	1.5	1.7	1.8	0.6	1.4	2.0	-0.7	0.9	1.6	1.5
Allergy	1.0	2.4	6.9	-0.6	-1.0	-2.2	-1.7	0.2	-1.7	-1.6	1.1	-1.1	-1.7	-1.9	-1.2	-1.6	-1.9	2.6	0.9	-0.6	-0.6	-2.5	-1.8	-0.4
Pain all over the body in last month	0.2	0.2	1.2	0.1	-0.0	-0.5	-0.4	-0.3	0.0	0.2	-0.3	1.0	0.2	-0.1	-0.0	0.5	0.5	0.4	0.2	0.4	1.1	0.2	0.0	-0.9
Diabetes (self-reported)	0.8	1.2	4.2	-0.3	1.5	0.8	0.5	2.0	1.0	1.1	2.1	0.9	1.2	1.0	1.1	1.1	1.1	0.1	1.5	1.0	-0.6	-0.4	1.0	0.7
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	1.2	-0.4	-0.7	-0.7	-0.9	1.1	-0.6	-0.7	-0.9	0.5	-0.9	-0.7	-0.9	-0.8	-0.7	0.1	-0.9	-1.1	0.5	0.4	-1.0	-0.4
Medication: Ramipril	0.7	0.9	1.9	0.1	-0.8	-1.2	-0.8	-0.5	-0.8	-0.9	-0.6	-1.1	-1.0	-1.1	-0.4	-1.1	-0.8	1.3	0.5	-1.0	0.7	-1.1	-1.4	-1.1
Medication: Simvastatin	0.2	0.3	2.7	-0.4	0.6	-0.1	-0.8	-0.4	-0.0	0.1	1.7	0.6	0.1	-0.2	-0.3	-0.1	-0.0	0.6	-0.2	0.6	-0.3	-0.4	0.1	0.7
Fluid intelligence score	0.5	1.1	3.7	-0.2	1.0	1.1	0.2	-1.6	1.3	1.1	0.8	1.3	0.8	1.1	0.9	1.2	1.2	-1.9	-0.3	0.9	0.3	0.5	1.1	0.5
Illnesses of siblings	2.1	2.9	7.3	-0.9	-1.6	-1.9	-0.7	0.3	-1.9	-1.8	-0.6	-2.6	-1.7	-1.9	-1.5	-2.1	-1.8	0.1	0.1	-2.4	-0.1	-2.7	-2.4	-2.0
Neuroticism score	0.5	1.1	5.5	0.2	0.8	0.7	0.9	-1.4	0.9	0.7	0.4	0.8	0.4	0.7	0.6	0.9	0.6	0.2	0.6	2.2	-1.3	0.7	1.4	2.4
Weight	0.1	0.6	3.2	1.2	-0.8	-0.4	-0.7	-1.8	-0.5	-0.5	-0.1	-1.1	0.4	-0.7	0.5	0.2	-0.3	0.0	-0.4	0.6	0.8	-0.2	0.4	-1.3
Impedance of arm (right)	0.7	3.3	7.7	-1.9	-1.3	-2.1	-1.1	1.5	-1.4	-1.8	0.5	-0.1	-2.4	-2.0	-2.5	-2.0	-1.9	2.7	1.2	-1.9	0.0	-2.5	-2.8	-0.4
Arm fat percentage (right)	1.3	5.0	12.7	0.6	2.4	2.3	1.2	-3.6	2.0	2.3	2.8	1.9	2.9	2.2	2.9	2.8	2.3	-1.1	-0.3	2.4	-2.0	1.4	3.0	1.1
Trunk fat-free mass	1.5	8.5	17.3	1.4	-4.2	-3.3	-2.7	0.8	-2.8	-3.6	-3.1	-3.7	-2.7	-3.7	-2.8	-2.9	-3.4	1.7	-0.2	-1.9	3.8	-2.1	-2.7	-3.8
Hip circumference	0.2	0.7	4.5	0.4	0.2	0.3	0.2	-2.1	-0.1	0.4	1.1	-0.3	1.2	0.2	1.1	1.1	0.5	-0.3	-0.5	1.4	0.0	0.2	1.4	-0.7
Time employed in main current job	0.5	0.6	3.0	0.4	-0.8	-0.6	-0.5	0.6	-0.4	-0.8	-0.5	-0.2	-0.1	-0.9	-0.5	-1.0	-0.8	0.2	0.4	-1.4	0.7	-0.5	-1.7	-0.5
Alcohol intake versus 10 years previously	1.9	2.9	5.8	1.2	2.0	1.4	1.0	-1.9	1.5	2.0	1.1	1.0	1.9	1.8	2.2	2.2	2.1	-1.5	0.8	2.4	-0.7	1.7	2.1	1.8
Father’s age at death	0.7	1.0	3.1	-0.1	-1.0	-0.7	-0.9	1.1	-0.7	-1.1	0.0	0.1	-0.6	-1.0	-0.5	-1.2	-1.1	-0.4	-0.6	-1.5	1.1	-1.6	-1.4	-1.8
Worrier / anxious feelings	1.1	2.0	7.5	-0.2	1.2	1.0	0.9	-1.9	0.9	1.0	1.0	1.8	0.9	1.1	1.0	1.1	0.9	-0.9	0.4	2.6	-1.8	1.6	1.7	2.7
Frequency of tiredness / lethargy in last 2 weeks	2.1	3.5	7.9	0.4	2.2	1.8	1.6	-0.9	2.0	2.5	-0.3	0.7	2.2	2.3	1.7	2.8	2.7	-1.1	0.3	2.3	-0.9	1.6	2.5	2.4
Falls in the last year	0.3	0.5	2.2	0.4	-0.1	-0.8	-0.1	0.8	0.1	-0.2	-1.5	0.4	-0.4	-0.5	-0.1	0.1	-0.0	1.1	1.2	0.3	1.4	0.5	-0.5	-0.1
Hair/balding pattern: Pattern 3	0.4	0.6	4.9	-1.4	0.3	-0.2	-0.2	0.4	-0.5	-0.1	-0.2	-0.8	-0.2	-0.0	0.4	-0.0	-0.2	-2.2	-1.1	-0.3	-1.4	0.3	0.1	0.3
Number of live births	0.6	0.9	3.0	1.2	-1.6	-0.6	-1.1	-0.1	-0.6	-1.2	-1.7	-0.3	-0.5	-1.1	-0.9	-0.6	-1.1	0.5	-0.7	0.6	1.7	0.1	-0.1	-0.7
Forced expiratory volume in 1-second (FEV1)	1.1	3.8	7.1	0.9	-2.6	-1.7	-1.7	1.5	-1.5	-2.3	-2.7	-1.5	-1.8	-2.1	-1.8	-2.6	-2.2	1.0	0.5	-2.3	2.2	-1.8	-2.6	-1.7
Pulse rate	1.5	2.5	6.8	1.8	1.3	1.7	1.7	-1.6	1.9	1.5	1.6	2.6	1.5	1.7	1.2	1.6	1.4	-0.4	1.4	2.3	0.4	0.9	2.1	1.1
Happiness	0.6	0.8	3.2	1.2	0.3	0.2	1.5	-0.9	0.8	0.3	1.0	0.4	-0.4	0.5	0.3	0.6	0.1	0.5	1.8	1.7	-0.4	-0.4	1.0	1.1
Noisy workplace	1.0	1.3	2.5	1.4	1.5	1.3	1.0	-0.1	1.3	1.5	0.4	-0.5	1.4	1.4	1.3	1.4	1.6	-0.8	-0.0	1.2	-0.5	0.9	1.3	1.0
Qualifications: A levels/AS levels or equivalent	1.5	3.2	7.7	-0.3	-2.0	-1.5	-1.6	-0.2	-1.8	-1.9	-0.7	-0.8	-1.4	-2.0	-1.6	-2.0	-1.6	1.2	0.3	-2.6	2.8	-2.3	-2.6	-2.7
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.9	-0.9	-0.1	-0.1	0.1	-0.5	0.1	-0.0	-0.4	0.8	-0.2	0.1	0.1	-0.1	-0.0	-0.2	0.4	-1.0	0.5	0.3	-0.6	-0.3
Mouth/teeth dental problems: Dentures	2.3	3.9	7.7	-0.8	2.3	1.7	1.8	-1.7	2.1	2.0	2.3	1.2	2.0	1.9	2.2	2.4	1.9	-1.0	-0.3	2.7	-1.6	2.6	2.8	2.4
Asthma	0.9	1.8	7.0	-0.3	1.0	1.7	1.0	-0.4	1.2	1.2	-1.1	0.9	0.9	1.6	1.2	1.2	1.2	-2.3	-1.4	0.6	-1.4	2.6	1.7	1.3
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.5	0.6	0.3	0.7	0.7	0.8	0.7	0.6	-1.2	1.0	0.3	0.8	0.2	0.7	0.6	-0.3	-0.2	-0.2	-0.2	0.8	0.3	-0.2
Medication: Cholesterol lowering	0.3	0.5	2.6	-0.1	0.9	-0.1	-0.6	-1.6	-0.2	0.5	1.6	0.6	0.4	0.1	0.5	0.2	0.3	-0.1	-0.9	0.2	-1.2	0.0	0.1	0.9
Depression (self-reported)	0.2	0.3	1.1	1.0	-0.3	-0.4	-0.5	0.3	-0.6	-0.4	-0.1	0.0	-0.4	-0.7	-0.4	-0.7	-0.4	0.5	1.0	0.3	0.5	-0.4	-0.7	0.7
Medication: Lansoprazole	0.3	0.4	3.1	1.8	0.2	0.5	-0.1	-1.2	0.4	0.4	-0.1	-0.1	0.3	0.6	0.4	0.2	0.4	-0.5	0.2	0.3	0.9	-0.1	0.5	-0.4
Prospective memory result	0.6	0.7	4.3	2.1	-0.0	0.1	-0.8	-0.9	0.7	0.1	0.5	0.5	0.4	0.1	0.0	-0.2	0.2	1.2	1.4	0.3	2.0	-0.3	-0.2	-0.8
Lung cancer (father)	3.5	4.1	11.0	-1.4	-2.3	-2.4	-1.9	-2.1	-2.0	-2.5	0.2	-0.4	-2.8	-2.4	-3.3	-1.8	-2.3	3.3	0.4	0.1	1.7	-2.0	-1.1	-1.3
Illnesses of mother	0.9	1.2	2.0	0.8	1.2	1.4	1.2	0.7	1.3	1.4	0.7	1.3	1.0	1.4	1.0	0.7	1.2	-0.2	1.3	0.8	-1.2	0.3	1.2	1.3
Forced expiratory volume in 1-second (FEV1), Best measure	2.8	8.9	16.6	0.4	-3.8	-3.2	-2.8	1.7	-2.9	-3.7	-2.7	-2.8	-3.1	-3.7	-3.0	-3.9	-3.6	1.6	0.3	-3.1	2.7	-3.3	-4.1	-2.8
Pulse wave Arterial Stiffness index	0.9	1.1	5.0	-0.4	0.9	0.9	0.2	-1.0	0.8	0.8	1.1	0.7	1.1	0.9	1.4	0.7	0.7	-1.9	-1.1	0.6	-2.2	0.4	1.1	0.5
Impedance of arm (left)	0.5	2.2	5.3	-1.9	-0.8	-1.6	-0.8	0.8	-1.3	-1.3	0.7	0.2	-2.1	-1.5	-1.8	-1.8	-1.4	2.3	1.0	-1.7	-0.7	-2.0	-2.3	0.3
Arm fat mass (right)	0.5	2.2	9.0	0.8	1.1	1.4	0.3	-3.0	1.1	1.3	1.6	0.8	2.1	1.2	2.1	1.9	1.3	-0.9	-0.4	1.8	-0.9	0.8	2.2	0.1
Trunk predicted mass	1.5	8.3	17.0	1.4	-4.1	-3.3	-2.6	0.8	-2.8	-3.6	-3.0	-3.6	-2.7	-3.7	-2.7	-2.9	-3.4	1.7	-0.2	-1.8	3.8	-2.1	-2.7	-3.8
Standing height	3.1	30.4	49.4	-0.4	-6.9	-6.6	-4.7	3.4	-5.4	-6.6	-4.9	-6.3	-6.1	-7.0	-6.2	-6.2	-6.3	4.1	0.3	-5.0	5.3	-5.2	-6.8	-5.5
Length of working week for main job	0.5	0.6	3.1	0.3	0.3	0.3	-0.2	1.2	0.5	0.5	-1.5	-1.3	-0.1	0.3	0.7	0.2	0.5	-1.8	-0.2	-0.4	-0.7	0.7	-0.2	0.4
Exposure to tobacco smoke at home	0.9	1.0	4.7	-0.2	1.2	0.0	0.6	-0.8	0.6	0.7	1.4	0.5	0.1	0.4	0.5	1.2	0.6	1.1	1.3	2.2	-0.8	1.0	1.0	1.8
Breastfed as a baby	0.7	0.8	5.9	-0.3	-0.5	-0.7	-0.4	2.4	-0.3	-0.8	0.8	0.5	-0.6	-0.8	-0.7	-0.9	-0.8	1.4	-0.5	-1.0	0.0	-0.9	-1.1	-1.0
Tense / ‘highly strung’	1.1	1.8	4.3	-0.4	-1.7	-1.4	-0.9	-0.3	-1.7	-1.6	-1.6	-1.8	-1.7	-1.6	-2.1	-1.7	-1.6	1.8	-0.5	-0.2	-0.2	-1.0	-1.0	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.5	8.7	1.0	1.9	1.9	2.0	-1.4	1.6	1.8	2.0	2.5	1.9	1.9	1.8	2.2	1.8	-0.3	0.8	3.0	-1.6	1.0	2.6	2.2
Hair/balding pattern: Pattern 4	1.3	3.1	6.6	1.8	2.0	2.6	1.7	-0.0	2.1	2.3	2.0	1.4	2.4	2.5	1.6	1.9	2.2	-1.6	1.0	0.9	-0.6	0.4	1.7	0.7
Birth weight of first child	1.5	2.7	6.3	-0.2	-1.6	-1.0	-1.0	0.4	-1.9	-1.6	-0.0	-1.8	-1.0	-1.7	-0.9	-2.3	-1.6	2.3	1.6	-2.0	2.1	-2.1	-2.5	-1.6
Peak expiratory flow (PEF)	0.4	0.8	4.0	-0.3	-1.2	-0.3	-0.9	0.6	-0.1	-1.0	-2.0	0.2	-0.8	-0.7	-0.6	-1.0	-1.0	-0.6	-1.4	-1.6	-0.6	-0.1	-0.9	-0.5
Pulse wave reflection index	1.0	1.2	8.5	-0.5	0.4	0.5	-0.6	-0.1	0.2	0.4	-0.2	-0.2	0.7	0.4	0.5	0.6	0.5	-2.4	-2.9	0.1	-2.7	0.6	0.8	0.4
Ever highly irritable/argumentative for 2 days	1.0	1.2	3.6	1.6	0.9	1.3	1.1	-1.2	1.0	1.1	0.5	0.4	1.1	1.2	0.9	1.1	1.1	0.6	1.7	1.9	0.4	0.1	1.5	0.8
Loud music exposure frequency	2.7	3.0	9.6	-0.6	-2.3	-2.1	-1.4	0.1	-1.0	-1.7	-2.6	-1.7	-1.8	-1.7	-2.3	-0.8	-1.4	1.3	-2.3	-1.7	1.2	-1.0	-1.2	-3.1
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	3.4	-0.5	0.1	0.2	-0.7	0.6	-0.3	0.1	1.2	0.1	0.6	-0.2	0.3	-0.2	0.1	0.3	0.2	-1.6	0.9	-1.8	-1.2	-1.3
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	3.6	1.0	-1.5	-1.1	-0.4	0.1	-0.8	-1.4	-0.7	-1.8	-1.4	-0.8	-1.2	-1.3	-1.4	-0.3	-0.8	-1.4	0.1	-1.3	-1.1	-1.9
Blood clot in the leg (DVT)	0.4	0.5	3.3	0.5	0.3	0.3	0.2	0.6	0.5	0.5	-0.3	0.0	-0.2	0.8	0.4	0.5	0.6	0.8	1.8	0.3	1.4	0.8	0.4	-0.2
Medication: Paracetamol	0.4	0.6	2.6	0.2	1.3	0.3	0.2	-0.3	0.8	1.0	0.8	1.6	0.1	0.6	1.2	0.7	0.8	1.0	0.8	-0.6	-0.8	0.3	-0.3	-0.1
Headache pain in last month	0.5	0.9	3.2	1.8	1.0	0.6	0.4	-0.7	0.6	1.1	-0.2	0.3	1.0	1.0	1.2	1.3	1.0	1.8	0.7	1.4	-0.1	0.2	0.9	0.6
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	4.7	0.2	-1.1	-0.1	-0.3	2.2	0.2	-0.7	-1.0	-0.5	-0.9	-0.3	-1.1	-0.6	-0.6	0.8	0.7	-0.4	1.9	-0.5	-0.3	-1.3
Glaucoma (self-reported)	0.3	0.4	2.1	1.4	-0.0	0.2	0.2	0.6	0.2	0.2	0.6	-0.1	0.7	0.4	0.5	0.3	0.3	0.3	0.7	0.5	0.7	-1.1	0.6	-0.5
Gout (self-reported)	0.6	0.8	4.8	-1.7	-0.1	-0.5	-0.4	1.1	-0.6	-0.4	0.2	-0.9	0.1	-0.4	-0.3	-0.3	-0.3	-0.9	-2.2	-1.1	-1.8	-0.6	-0.2	-0.6
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	3.8	0.8	-0.0	-0.2	-0.3	-1.9	-0.1	0.1	-1.7	-0.6	0.2	-0.1	0.0	0.2	0.3	0.8	0.7	0.7	0.7	1.1	0.3	0.5
Medication: Amlodipine	3.9	5.5	8.5	-0.1	2.7	2.8	2.6	-2.3	2.9	2.8	0.5	1.7	2.3	2.9	2.6	2.9	2.8	-2.3	0.6	1.9	-1.4	2.4	2.6	2.7
Medication: Ventolin 100micrograms inhaler	1.8	2.3	6.1	0.6	1.5	2.0	0.7	-0.4	1.9	1.6	-0.4	1.5	1.5	2.0	1.6	1.8	1.5	-0.7	0.2	1.5	-1.0	2.5	2.4	1.2
Birth weight	1.9	4.2	9.1	0.2	-1.9	-2.0	-1.0	1.2	-2.6	-2.2	-0.3	-3.0	-1.9	-2.6	-1.7	-2.3	-2.1	2.2	1.4	-1.8	2.0	-2.9	-2.7	-2.2
Chronic bronchitis/emphysema (mother)	0.9	1.0	3.7	-0.1	0.8	0.8	1.5	0.0	0.7	0.9	0.5	-0.0	1.3	0.8	0.3	1.8	1.0	-0.7	-0.6	1.8	-1.0	1.0	1.9	0.6
High blood pressure (siblings)	2.3	3.2	8.0	1.2	1.5	2.1	0.8	-0.1	1.9	1.9	-0.2	2.0	2.2	2.3	1.7	2.3	2.0	-1.3	-0.7	2.2	-0.5	2.8	2.7	1.8
Forced vital capacity (FVC), Best measure	2.2	8.1	14.7	0.3	-3.8	-3.1	-2.3	1.6	-2.7	-3.5	-3.1	-2.9	-2.9	-3.5	-2.9	-3.6	-3.4	0.9	-0.1	-3.0	2.8	-2.7	-3.8	-2.7
Body fat percentage	1.8	7.1	13.5	0.4	3.1	2.7	1.3	-3.7	2.3	2.9	3.2	2.4	3.4	2.8	3.5	3.2	3.0	-1.7	-0.5	2.8	-2.5	1.8	3.4	1.8
Leg fat percentage (right)	2.4	8.6	15.3	1.1	3.3	3.3	1.5	-3.1	2.9	3.3	3.5	3.0	3.9	3.3	3.9	3.5	3.3	-1.8	-0.4	2.8	-2.4	2.2	3.8	1.9
Arm fat-free mass (right)	0.6	3.0	8.3	1.5	-2.5	-1.7	-1.9	-0.3	-1.5	-1.9	-2.2	-2.6	-1.2	-2.0	-1.2	-1.5	-1.7	0.3	-0.5	-0.8	2.9	-1.0	-1.1	-2.6
Exposure to tobacco smoke outside home	1.3	1.8	5.5	0.8	1.4	1.3	1.6	0.4	1.5	1.3	1.1	1.3	1.1	1.4	1.1	1.6	1.3	0.3	1.6	2.3	-0.1	1.1	1.9	1.4
Comparative body size at age 10	1.4	3.9	6.1	2.0	1.7	2.5	2.0	-2.0	2.4	2.0	1.6	2.4	2.4	2.3	2.4	2.1	2.1	-0.9	1.6	2.0	1.1	1.9	2.2	0.3
Number of full brothers	2.0	2.5	4.6	0.1	-2.1	-1.3	-1.5	-0.3	-1.6	-1.7	-1.8	-1.3	-1.2	-1.6	-1.7	-1.7	-1.6	0.1	-1.0	-2.1	2.0	-1.7	-1.9	-2.1
Worry too long after embarrassment	1.0	1.7	5.1	-0.2	1.3	1.2	0.9	-1.8	0.6	1.2	0.8	1.4	1.3	1.2	1.2	1.3	1.3	-1.2	-0.2	2.3	-1.4	0.7	1.8	2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	2.3	0.3	-0.2	-0.8	0.1	0.0	-0.5	-0.3	0.2	0.0	-0.6	-0.5	-0.5	0.1	-0.3	1.5	0.4	0.9	-0.2	-0.6	0.1	-0.2
Wheeze or whistling in the chest in last year	1.0	1.7	11.2	-0.5	0.4	0.8	1.5	0.1	0.8	0.9	-2.5	-0.2	0.4	0.9	0.1	1.3	0.9	-1.3	-1.9	0.8	-0.9	3.4	1.4	1.2
Number of children fathered	1.4	1.6	4.3	-0.4	-1.6	-1.4	-1.0	0.6	-2.1	-1.8	-0.1	-1.3	-1.4	-1.6	-1.9	-1.6	-1.9	1.0	-0.2	-0.2	0.6	-1.0	-0.8	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	5.7	-0.5	0.3	0.1	-0.1	1.8	-0.3	-0.0	2.4	0.4	-0.2	-0.2	-0.3	-0.3	-0.2	0.6	1.0	-0.2	0.4	-1.4	-0.3	-0.7
Age at first live birth	0.5	0.8	5.7	-0.2	-0.4	0.3	-0.3	0.6	0.4	-0.2	-1.2	0.0	0.7	-0.4	0.2	-0.7	-0.1	-1.0	0.3	-2.4	1.3	-0.8	-1.8	-1.1
Pulse wave peak to peak time	1.5	1.8	6.5	0.4	-1.4	-1.4	-0.5	1.0	-1.1	-1.2	-1.3	-1.1	-1.5	-1.4	-1.8	-1.1	-1.1	2.2	1.1	-1.0	2.6	-0.8	-1.6	-1.0
Health satisfaction	0.4	0.6	2.8	0.8	0.5	0.3	0.6	-0.4	0.3	0.8	0.2	-0.9	0.6	0.6	0.4	0.8	0.7	-1.7	-0.8	0.3	-1.3	0.4	0.9	0.6
Shortness of breath walking on level ground	1.9	2.2	4.3	1.4	1.6	1.6	1.6	-0.2	1.8	1.9	0.3	0.3	1.6	1.9	1.3	1.6	1.7	-2.1	-1.4	0.3	-1.9	1.8	1.4	1.2
Qualifications: College or University degree	0.9	2.8	12.1	-0.8	-1.5	-1.2	-0.0	-0.4	-1.1	-1.6	-0.3	-0.0	-1.7	-1.5	-1.3	-2.0	-1.5	1.3	0.6	-3.5	1.7	-2.2	-2.8	-2.6
Eye problems/disorders: None of the above	0.2	0.3	0.6	-0.3	0.3	0.3	0.8	-0.5	0.6	0.6	-0.5	0.7	0.6	0.1	0.2	0.5	0.7	0.1	-0.5	-0.8	0.7	0.4	-0.3	-0.7
Mouth/teeth dental problems: Loose teeth	1.3	1.5	4.1	0.4	1.7	1.0	2.0	-0.1	1.5	1.6	0.7	1.7	1.3	1.4	1.3	1.5	1.6	-0.7	-0.3	0.4	-1.5	0.9	0.8	0.8
Emphysema/chronic bronchitis	0.3	0.4	1.6	-1.3	-0.6	-0.5	-0.4	0.3	-0.4	-0.5	-0.7	0.0	-0.6	-0.6	-0.8	-0.2	-0.4	0.1	-0.8	-0.6	0.9	0.1	-0.5	-0.6
Medication for pain relief, constipation, heartburn	0.4	0.7	1.9	-0.9	-1.4	-0.3	0.0	0.3	-1.1	-1.3	0.1	-1.2	-0.5	-0.9	-1.1	-1.1	-1.2	-0.6	-0.4	0.9	0.5	-0.3	0.1	0.6
Neck or shoulder pain in last month	2.2	3.1	7.0	0.6	1.7	2.3	1.8	1.5	2.6	2.0	-0.0	1.2	1.7	2.4	1.2	2.1	2.1	-2.3	-0.3	1.6	-0.7	1.6	2.5	1.4
Medication: Blood pressure	0.2	0.4	3.1	-0.8	0.2	-0.4	-0.3	-1.8	-0.6	0.0	0.0	-0.7	-0.1	-0.2	0.3	-0.1	-0.1	-0.6	-0.6	-0.1	-1.6	0.3	-0.1	0.7
Angina (self-reported)	3.9	5.1	10.0	0.5	2.7	1.9	1.6	-2.2	2.2	2.5	2.2	2.2	2.1	2.5	2.3	2.9	2.5	-1.5	-0.4	2.7	-2.4	2.0	3.2	2.3
Migraine (self-reported)	0.3	0.4	1.8	0.5	0.1	0.0	-0.5	1.1	-0.2	-0.1	1.3	-0.3	0.1	-0.2	-0.3	-0.5	-0.2	0.9	0.5	-1.1	0.4	-1.0	-0.9	-0.6
Medication: Ibuprofen	0.2	0.2	1.2	0.6	0.3	0.5	0.3	1.1	0.4	0.4	-0.9	0.5	-0.1	0.6	-0.1	0.5	0.4	0.1	-0.4	0.1	-0.3	0.7	0.4	-0.3
Medication: Allopurinol	0.2	0.3	2.1	-0.3	-0.3	-0.3	-0.8	0.1	0.2	-0.3	0.3	-0.5	0.1	-0.3	-0.2	-0.2	-0.2	-1.2	-1.5	-0.6	-0.0	-0.6	-0.2	-1.0
Medication: Omeprazole	0.3	0.4	1.5	0.1	0.4	0.2	-0.0	-0.5	0.7	0.7	-1.2	0.2	0.3	0.6	0.4	0.9	0.8	-0.2	-0.5	0.7	-0.0	1.2	0.9	0.5
Medication: Seretide 50 evohaler	0.9	1.0	6.8	-2.1	-0.2	-0.2	-0.3	1.2	-0.5	-0.4	0.3	0.8	-0.4	-0.3	-0.4	-0.4	-0.7	-0.3	-1.9	-0.9	-2.6	0.4	-0.3	0.4
Mean time to correctly identify matches	2.2	4.2	11.9	-1.8	-1.5	-2.8	-1.4	0.2	-2.5	-2.1	2.2	-0.8	-1.3	-2.5	-1.3	-2.2	-2.1	1.5	0.1	-2.5	0.8	-3.4	-2.9	-2.8
Heart disease (mother)	0.3	0.3	0.8	0.1	0.9	0.6	0.0	0.2	0.8	0.8	0.2	-0.3	0.6	0.9	0.9	0.7	0.8	-0.8	-0.2	-0.4	-0.0	0.8	0.2	-0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.3	2.7	5.7	-0.1	2.0	1.9	0.7	-1.5	2.2	1.9	0.4	1.9	1.6	2.4	2.1	1.8	2.0	-1.0	-0.2	0.9	-2.1	1.9	2.0	1.1
Whole body fat mass	0.6	2.6	10.6	0.8	1.5	1.4	0.4	-3.3	1.3	1.6	2.0	1.0	2.2	1.4	2.4	2.0	1.6	-1.0	-0.4	1.8	-1.0	0.9	2.2	0.4
Leg fat mass (right)	0.7	2.7	8.4	1.0	1.5	1.6	0.3	-2.9	1.4	1.6	2.2	1.3	2.4	1.5	2.4	2.0	1.6	-1.0	-0.6	1.7	-1.0	0.9	2.3	0.2
Arm predicted mass (right)	0.5	2.7	7.8	1.6	-2.4	-1.7	-1.8	0.1	-1.5	-1.8	-2.0	-2.6	-1.0	-1.9	-1.0	-1.3	-1.6	0.3	-0.2	-0.6	2.8	-1.0	-1.0	-2.6
Pulse rate, automated reading	2.8	9.1	14.3	3.1	3.5	3.4	3.0	-1.6	3.3	3.5	2.9	2.6	3.4	3.6	3.4	3.4	3.4	-1.2	2.4	3.8	-0.6	2.2	3.7	2.8
Alcohol intake frequency.	2.2	5.0	16.4	2.6	2.3	1.5	1.5	-1.8	1.8	2.2	1.7	1.4	2.2	1.7	2.5	2.6	2.3	1.1	3.1	4.1	0.8	1.9	2.6	2.9
Comparative height size at age 10	1.5	8.3	14.5	0.5	-3.4	-3.1	-1.9	2.7	-2.2	-3.2	-2.8	-3.5	-2.9	-3.4	-2.8	-3.0	-3.0	2.2	0.5	-3.1	3.4	-2.8	-3.8	-3.6
Number of full sisters	2.6	3.2	6.3	-1.5	-2.4	-2.5	-1.9	1.4	-2.5	-2.2	-1.2	-1.9	-1.9	-2.3	-2.2	-1.5	-2.0	1.5	-1.7	0.2	1.2	-0.7	-0.4	-1.8
Suffer from ‘nerves’	0.5	0.8	2.2	-1.0	-0.7	-1.5	-0.9	-1.3	-0.9	-1.0	-0.2	-0.6	-1.2	-1.4	-1.0	-0.8	-1.0	1.0	-0.7	0.8	-0.3	-0.4	-0.4	1.0
Overall health rating	3.5	7.4	12.5	1.5	3.2	3.0	2.8	-0.6	3.0	3.5	2.3	2.9	3.2	3.2	3.0	3.5	3.5	-1.0	1.6	3.3	-0.9	2.0	3.5	2.4
Chest pain or discomfort	3.6	5.2	9.0	2.2	2.5	2.6	3.0	-1.6	2.5	2.9	1.0	1.8	2.7	2.8	2.4	3.0	2.9	-1.0	1.4	2.2	-0.3	2.5	2.6	1.6
Had major operations	1.7	1.9	5.5	2.3	1.3	1.4	2.4	0.9	1.2	1.5	0.9	0.6	2.2	1.4	1.6	1.4	1.6	-0.2	1.7	1.1	1.4	0.5	0.8	-0.1
Age at last live birth	0.5	0.7	4.0	-0.8	-0.4	-0.1	-0.6	0.4	0.1	-0.2	-0.7	0.4	0.5	-0.4	0.1	-0.1	0.1	-2.0	-1.0	-1.7	0.7	-0.7	-0.9	-1.4
Family relationship satisfaction	0.5	0.6	1.6	0.3	-0.8	-1.0	-0.7	-0.3	-0.9	-0.8	-0.3	-0.8	-1.0	-1.1	-1.3	-0.5	-0.7	1.3	0.3	0.8	-0.1	-0.4	-0.2	0.9
Leg pain on walking	0.6	0.8	2.8	0.2	0.7	0.8	0.6	-1.7	0.8	0.9	0.1	1.0	0.6	1.0	1.1	0.9	0.9	-1.2	-0.8	0.0	-1.0	1.1	0.8	0.3
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	4.8	-0.7	0.9	-0.2	-0.5	0.4	-0.2	0.3	1.0	0.0	0.2	-0.0	0.3	0.6	0.3	0.4	-0.8	2.2	-2.0	1.0	1.1	2.0
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.8	0.8	0.6	1.1	0.0	-0.1	0.9	0.7	0.5	0.3	0.9	0.6	0.7	0.8	0.8	0.7	1.7	1.6	0.5	0.2	0.9	0.9
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.4	-1.2	-1.0	-1.0	-0.9	0.6	-1.4	-1.3	-0.2	-1.5	-1.1	-1.3	-1.4	-1.4	-1.4	0.3	-0.7	-0.6	-0.3	-1.0	-1.1	0.0
Medication: Aspirin	0.4	0.6	3.2	1.0	0.6	-0.5	-0.2	-1.1	0.3	0.3	1.8	-0.0	-0.1	0.2	0.4	0.1	0.2	1.3	0.9	-0.3	0.1	-1.4	-0.3	-0.8
Supplements: Vitamin C	0.7	0.8	2.8	-1.0	0.8	0.5	0.2	-0.1	0.3	0.8	1.1	1.1	0.6	0.8	0.5	0.8	0.8	-1.7	-0.9	0.4	-1.5	1.2	0.8	0.8
Knee pain experienced in last month	3.8	5.9	12.6	1.1	2.9	2.3	2.6	-1.5	2.9	2.9	0.3	1.4	2.1	2.8	3.1	2.9	2.7	-0.6	0.4	2.7	-2.3	3.5	2.9	3.0
Hypertension (Self-reported)	0.8	2.1	5.9	-1.1	1.7	1.2	1.0	-1.3	1.5	1.6	0.3	0.7	1.3	1.6	1.6	1.4	1.6	-2.3	-0.4	1.2	-2.4	1.4	1.6	1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	2.2	1.4	0.3	0.5	0.1	-0.8	0.3	0.4	-1.5	-0.1	-0.0	0.5	0.4	0.7	0.5	0.4	0.1	1.1	-0.5	1.3	0.9	0.7
Illnesses of father: Heart disease	2.1	2.9	4.8	1.5	1.9	2.2	0.9	-1.8	2.1	1.9	-0.5	1.8	1.9	2.0	2.1	1.8	1.8	-1.9	-0.3	0.9	-1.6	2.0	1.7	1.6
Illnesses of siblings: Diabetes	0.3	0.4	1.3	1.1	-0.1	-0.3	-0.4	1.0	0.1	-0.2	-0.3	1.1	-0.3	-0.3	0.3	-0.6	-0.3	0.6	0.6	-0.8	1.1	-0.3	-1.0	0.1
Smoking status: Previous	0.8	1.2	3.8	-0.4	0.7	1.0	0.1	-0.8	0.7	0.7	2.0	1.8	1.2	1.0	0.7	1.1	0.6	-1.4	-1.0	1.2	-1.6	-0.3	1.8	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	3.4	7.0	13.5	0.1	-3.2	-2.9	-2.7	0.1	-2.5	-3.0	-1.7	-2.8	-2.5	-3.1	-2.5	-2.8	-2.7	2.4	1.0	-2.3	3.7	-3.0	-3.1	-3.5
Whole body fat-free mass	1.1	6.5	13.4	1.2	-3.7	-2.9	-2.4	0.3	-2.5	-3.1	-2.7	-3.4	-2.2	-3.3	-2.2	-2.5	-2.9	1.3	-0.3	-1.5	3.3	-1.9	-2.2	-3.5
Leg fat-free mass (right)	0.8	4.1	8.7	0.7	-3.0	-2.4	-1.7	-0.6	-2.2	-2.5	-1.9	-2.9	-1.8	-2.7	-1.6	-1.9	-2.4	1.2	-0.3	-0.8	2.6	-1.6	-1.6	-2.8
Arm fat percentage (left)	1.5	6.1	15.5	0.8	2.7	2.6	1.3	-3.9	2.0	2.6	3.1	2.2	3.1	2.5	3.3	3.0	2.6	-1.2	-0.2	2.6	-2.2	1.5	3.2	1.4
Average weekly red wine intake	1.0	1.5	8.8	0.3	-0.9	-0.7	-1.1	-0.2	-1.1	-0.8	0.6	0.0	-0.4	-0.6	-0.6	-1.1	-0.8	-0.1	-0.1	-2.1	1.3	-3.0	-1.1	-2.8
Handedness (chirality/laterality): Left-handed	3.7	4.5	10.1	-0.6	-2.8	-2.6	-1.8	0.3	-2.3	-2.8	-1.1	-1.3	-2.6	-2.6	-3.2	-2.7	-2.7	1.8	-0.8	-1.8	1.6	-1.8	-2.2	-2.0
Mood swings	0.2	0.4	1.5	1.0	0.5	0.7	0.5	-1.2	0.8	0.5	-0.5	-0.2	0.4	0.5	0.4	0.6	0.3	0.0	-0.1	0.6	-0.9	0.6	0.5	1.2
Loneliness, isolation	0.9	1.3	5.8	1.8	0.9	0.9	1.5	-0.9	0.6	0.8	-0.4	-0.0	0.5	0.6	0.4	1.3	0.9	0.5	1.6	2.4	0.0	1.0	1.5	1.6
Long-standing illness, disability or infirmity	2.3	3.5	7.1	-0.4	2.7	1.7	1.8	-0.8	1.7	2.4	1.0	1.4	2.3	1.9	2.5	2.5	2.5	-0.8	0.8	1.3	-2.4	2.0	1.8	2.1
Ever had bowel cancer screening	1.6	1.9	3.8	-0.8	1.8	1.4	1.2	0.9	1.7	1.7	2.0	1.6	1.6	1.8	1.5	1.5	1.6	-0.5	-0.3	0.4	-1.0	1.5	1.4	0.9
Diabetes diagnosed by doctor	1.3	2.1	6.2	-0.4	2.1	1.2	0.8	2.0	1.4	1.6	2.5	1.4	1.6	1.3	1.6	1.5	1.6	-0.0	1.7	1.6	-1.1	0.1	1.5	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.8	2.8	0.9	-0.9	-0.5	-1.2	1.3	-0.6	-0.7	0.6	0.7	-0.3	-0.7	-0.6	-0.6	-0.7	0.6	1.0	-0.3	1.7	-1.0	-0.9	-1.1
Friendships satisfaction	0.6	0.7	3.6	0.3	0.6	0.1	0.8	-1.9	0.3	0.4	0.1	0.6	-0.2	0.3	0.3	0.9	0.4	0.2	0.4	1.4	-1.3	0.7	1.0	1.8
Qualifications: nursing, teaching	1.2	1.9	5.5	0.1	1.4	1.6	1.6	-2.3	1.3	1.3	1.7	2.3	1.5	1.2	1.3	1.2	1.4	-0.7	1.5	1.2	0.4	0.1	1.1	0.8
Commuting to job workplace: Walk	0.3	0.3	1.3	-1.1	-0.5	-0.7	-0.2	0.9	0.2	-0.3	-0.4	1.1	-0.7	-0.2	-0.5	-0.1	-0.4	0.2	-1.0	-0.0	0.3	0.4	0.2	0.0
Eye problems/disorders: Cataract	0.1	0.1	0.3	-0.0	-0.1	-0.3	0.1	-0.1	0.1	-0.2	0.0	-0.6	-0.5	-0.2	-0.1	-0.1	-0.1	-0.1	0.4	0.3	-0.0	-0.5	0.2	0.3
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	3.6	0.5	-0.2	-0.5	0.4	1.5	-0.5	-0.5	1.2	-0.4	-0.4	-0.5	-0.4	-0.7	-0.6	0.7	1.2	-1.1	0.1	-1.9	-1.2	-0.7
Medication for cholesterol	0.9	1.4	3.4	-0.7	-1.7	-1.5	-0.3	1.0	-1.9	-1.8	-0.7	-0.9	-1.5	-1.8	-1.2	-1.6	-1.8	0.1	-1.3	-0.4	-0.4	-0.2	-1.0	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	4.7	-1.2	0.7	-0.2	-0.4	0.8	-0.2	0.3	0.7	2.2	0.2	0.1	0.1	0.7	0.3	0.9	0.1	-0.0	-1.1	-0.5	-0.0	0.1
Back pain experienced in last month	1.0	1.5	3.6	-1.3	-1.2	-1.4	-0.7	0.7	-1.2	-1.2	-1.9	-0.3	-1.8	-1.1	-1.7	-0.9	-1.3	1.7	-1.0	-1.5	-0.2	-0.1	-1.3	-1.0
Mineral and other dietary supplements	2.2	3.0	6.2	0.4	-2.3	-2.5	-1.6	0.2	-1.4	-2.2	-1.3	-1.5	-2.3	-2.3	-2.3	-1.6	-2.1	2.1	-0.3	-0.7	1.7	-1.3	-1.6	-1.4
Breast cancer (self-reported)	1.2	1.5	5.2	0.0	-1.4	-1.1	-0.8	0.2	-1.2	-1.2	0.2	-0.7	-0.7	-1.1	-0.9	-1.2	-1.1	1.9	0.5	-0.8	2.2	-1.7	-1.0	-2.3
Asthma (self-reported)	1.1	2.2	8.5	-0.1	1.1	1.9	1.1	-0.5	1.4	1.3	-1.1	1.0	1.1	1.8	1.3	1.4	1.3	-2.2	-1.3	0.9	-1.4	2.9	2.0	1.4
Osteoporosis (self-reported)	0.4	0.4	1.7	-0.7	-0.3	-0.6	-0.5	0.8	-0.8	-0.6	1.0	-1.3	-0.5	-0.7	-0.1	-0.6	-0.8	0.5	0.1	0.3	-0.4	-1.0	-0.5	0.3
Osteoarthritis (self-reported)	1.2	1.5	3.4	1.0	1.0	1.2	1.7	-1.0	1.3	1.3	0.2	1.3	1.2	1.5	1.2	1.6	1.3	-0.4	0.4	1.6	0.1	1.8	1.8	0.4
Medication: Aspirin	0.4	0.5	2.5	0.6	0.6	-0.6	-0.5	-1.2	0.2	0.2	1.6	-0.2	-0.3	0.1	0.4	0.0	0.1	1.3	0.7	-0.3	-0.3	-1.3	-0.2	-0.7
Medication: Gliclazide	0.4	0.4	4.9	0.8	-0.4	-0.2	-0.1	2.2	0.0	-0.5	-0.2	0.7	-0.4	-0.2	-0.7	-0.5	-0.5	0.2	0.4	0.5	0.8	0.2	0.1	0.2
Illnesses of father: None of the above (group 1)	0.4	0.5	1.9	-1.4	-0.8	-0.9	-0.1	0.5	-0.7	-0.8	0.2	-0.1	-0.9	-0.6	-1.0	-0.5	-0.8	1.0	-0.1	-0.7	-0.4	-0.6	-0.7	-0.4
Smoking status: Current	1.2	2.0	3.5	-1.2	1.8	1.3	1.9	-0.5	1.6	1.7	0.8	0.8	0.8	1.8	0.5	1.5	1.6	-1.6	0.1	1.2	-1.2	1.9	1.7	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.2	5.7	0.3	-1.3	-1.2	-1.6	1.7	-0.8	-1.4	-1.0	-0.3	-1.5	-1.4	-0.7	-2.3	-1.4	1.2	1.3	-2.3	1.5	-1.9	-2.4	-1.3
Whole body water mass	1.1	6.1	12.5	1.2	-3.5	-2.8	-2.3	0.3	-2.5	-3.0	-2.5	-3.4	-2.1	-3.2	-2.1	-2.4	-2.8	1.3	-0.2	-1.4	3.3	-1.9	-2.1	-3.4
Leg predicted mass (right)	0.8	4.0	8.6	0.6	-2.9	-2.4	-1.7	-0.6	-2.2	-2.5	-1.8	-2.9	-1.7	-2.8	-1.6	-1.9	-2.4	1.2	-0.3	-0.8	2.6	-1.6	-1.6	-2.8
Arm fat mass (left)	0.7	3.0	10.5	1.1	1.6	1.7	0.7	-3.2	1.3	1.7	2.1	1.2	2.4	1.6	2.5	2.2	1.8	-1.1	-0.2	2.0	-1.0	0.9	2.5	0.3
Number of self-reported non-cancer illnesses	2.5	4.4	8.3	-0.5	2.9	1.9	1.7	-0.8	2.2	2.7	1.6	2.3	2.2	2.4	2.6	2.7	2.6	-0.7	0.6	1.8	-2.3	2.4	2.3	2.2
Average weekly champagne plus white wine intake	1.8	2.4	7.2	0.6	-1.8	-1.4	-1.4	0.3	-0.9	-1.5	-0.2	0.1	-1.4	-1.4	-2.1	-1.8	-1.4	1.6	1.4	-1.6	2.7	-1.8	-2.0	-2.5
Miserableness	0.6	1.1	2.4	0.2	1.0	1.0	1.5	-0.8	1.0	1.0	-0.4	1.0	1.2	1.1	1.0	1.4	1.0	-1.0	-0.3	1.5	-0.7	0.7	1.6	1.4
Guilty feelings	0.6	0.8	1.9	0.6	0.6	1.2	0.8	-1.4	0.8	0.8	-0.4	1.3	0.6	1.1	0.9	0.9	0.8	-0.7	0.5	1.0	-0.8	0.9	1.1	1.2
Wears glasses or contact lenses	2.4	2.7	8.5	-0.6	2.4	1.9	1.5	-0.8	1.2	1.9	2.9	0.6	1.9	2.0	2.2	1.7	1.9	-1.1	1.4	1.6	-1.0	0.3	1.8	1.3
Ever taken oral contraceptive pill	0.6	0.7	5.0	2.2	-0.3	0.4	0.8	-1.7	0.9	0.0	-0.5	0.8	0.6	0.3	0.2	0.4	0.2	-0.9	0.4	0.7	1.0	-0.1	0.4	0.2
Hearing aid user	6.1	6.9	13.5	2.2	2.6	2.9	2.9	-1.7	3.1	3.0	1.4	3.7	2.9	3.0	2.8	3.2	3.1	-0.9	1.2	3.0	-0.1	2.9	3.1	2.1
Mother’s age at death	1.3	1.6	3.8	-0.0	-1.8	-1.2	-1.1	1.0	-1.5	-1.6	-1.9	-0.6	-0.8	-1.4	-1.3	-1.5	-1.4	0.8	-0.9	-1.0	1.9	-0.5	-1.4	-0.9
Financial situation satisfaction	0.5	0.6	3.2	-0.0	0.5	0.5	0.8	-1.2	0.6	0.6	0.7	0.5	0.7	0.6	0.4	0.9	0.6	-0.0	0.4	1.8	-0.3	0.5	1.5	1.2
Tinnitus: Yes, now most or all of the time	0.9	1.0	4.0	-1.1	0.8	0.5	0.2	0.9	0.8	0.9	0.2	-0.6	0.4	1.0	1.1	1.0	1.0	-1.8	-1.7	0.1	-2.0	0.8	1.0	0.7
Commuting to job workplace: Public transport	2.4	2.8	5.2	-1.7	-1.6	-2.2	-0.8	1.4	-2.2	-1.8	-0.9	-0.7	-2.1	-2.0	-1.7	-1.9	-1.9	1.5	-1.8	-2.2	-0.1	-1.1	-2.3	-1.5
Eye problems/disorders: Glaucoma	0.4	0.4	1.3	1.0	-0.9	-0.8	-1.0	-0.0	-0.7	-0.8	0.3	-0.8	-0.4	-0.4	-0.6	-0.5	-0.8	-0.0	-0.5	0.4	0.5	-1.1	0.3	-0.7
Medication: Blood pressure	1.4	2.6	5.6	-0.6	2.0	1.8	1.1	-1.4	2.4	2.0	1.1	1.4	1.7	2.2	1.6	2.2	2.1	-0.3	1.0	1.6	-0.8	1.2	2.2	0.8
Pain type(s) experienced in last month: Hip pain	1.0	1.3	5.3	-0.7	0.9	0.6	1.2	1.0	0.6	0.8	-0.8	0.1	0.6	0.8	0.5	1.0	0.7	-0.8	-1.1	1.2	-2.3	2.1	1.2	2.1
Supplements: Fish oil (including cod liver oil)	4.2	5.5	10.4	-0.2	3.1	3.2	2.2	-0.5	2.2	3.0	2.0	2.8	2.9	3.0	3.2	2.4	3.0	-2.5	0.3	0.7	-2.2	1.6	1.9	2.0
High cholesterol (Self-reported)	0.2	0.3	2.4	0.4	0.2	-0.1	-1.1	0.1	-0.3	-0.1	1.5	0.3	0.3	-0.4	0.0	-0.2	-0.1	0.8	0.5	0.5	0.6	-0.8	-0.1	0.3
Medication: Bendroflumethiazide	2.9	4.4	10.9	-0.1	2.8	2.5	0.9	-0.8	2.2	2.6	1.2	1.5	1.8	2.7	2.4	2.4	2.3	-0.6	1.0	2.6	-2.0	1.9	2.6	3.3
Medication: Paracetamol	1.0	1.6	3.3	1.6	1.8	1.1	1.0	-0.8	1.5	1.6	1.2	1.7	0.9	1.4	1.7	1.4	1.5	1.2	1.3	0.6	-0.3	0.9	0.8	0.2
Medication: Lisinopril	0.4	0.5	2.0	-0.2	-0.5	-1.1	-0.5	-1.1	-1.0	-0.6	-0.3	-1.4	-0.6	-0.8	-0.7	-0.4	-0.6	1.4	-0.5	-0.4	-0.2	-0.5	-0.5	-0.4
Medication: Atorvastatin	0.9	1.2	3.7	-0.3	1.3	0.7	0.5	-1.9	0.5	1.1	0.4	0.4	0.8	1.1	1.1	1.0	1.0	-1.1	-0.8	0.8	-1.7	1.8	1.1	1.4
Illnesses of father: High blood pressure	0.4	0.5	2.2	1.2	0.4	0.6	-0.1	1.5	0.7	0.5	-1.0	0.5	0.6	0.3	0.8	0.4	0.6	0.5	0.4	0.5	0.3	0.6	0.2	0.7
Alcohol drinker status: Never	0.8	1.0	5.5	0.6	1.2	0.9	0.6	-0.4	0.8	0.8	2.4	0.9	0.7	0.7	1.0	0.6	0.6	0.9	1.2	1.3	-0.7	0.4	0.8	1.6
Ever smoked	1.1	1.9	6.1	-0.5	1.0	1.4	1.5	-0.7	1.4	1.2	1.6	2.0	1.3	1.6	0.2	1.3	1.2	-2.5	-1.4	1.0	-1.1	0.9	2.0	-0.1
Basal metabolic rate	0.8	4.2	9.2	1.1	-3.0	-2.3	-2.0	-0.2	-2.1	-2.5	-2.2	-2.9	-1.6	-2.7	-1.6	-1.9	-2.3	0.9	-0.4	-1.0	2.7	-1.4	-1.6	-2.9
Leg fat percentage (left)	2.7	9.7	17.9	1.1	3.5	3.4	1.6	-3.5	2.9	3.5	3.5	3.0	4.1	3.5	4.1	3.8	3.5	-1.9	-0.7	3.3	-2.4	2.5	4.2	2.0
Arm fat-free mass (left)	0.5	2.8	8.0	1.7	-2.4	-1.7	-1.7	0.4	-1.4	-1.9	-2.1	-2.8	-0.9	-1.9	-1.1	-1.2	-1.6	0.4	-0.4	-0.5	2.6	-0.8	-0.9	-2.6
Number of operations (self-reported)	3.1	4.7	8.2	0.3	2.6	2.4	2.1	0.3	2.0	2.6	1.0	2.4	2.5	2.6	2.7	2.8	2.7	-1.0	0.6	2.2	-1.5	2.9	2.4	2.3
Average weekly beer plus cider intake	0.4	0.6	1.5	-0.1	0.4	0.8	1.2	1.1	1.0	0.5	-0.5	1.2	0.5	0.9	-0.2	0.5	0.4	-1.2	0.4	0.7	0.7	0.7	0.9	0.2
Irritability	0.2	0.4	1.3	0.1	-0.2	-0.6	-0.2	0.3	0.0	-0.3	0.1	-0.5	-0.6	-0.4	-0.7	-0.8	-0.5	1.0	1.0	-1.1	0.3	-0.8	-1.1	-0.7
Risk taking	2.1	3.0	6.6	-1.1	-2.1	-1.9	-1.4	2.0	-1.6	-2.1	-1.9	-1.6	-2.6	-1.9	-2.3	-2.3	-2.1	0.8	-0.2	-1.7	0.4	-1.1	-2.0	-1.3
Ever had prostate specific antigen (PSA) test	0.5	0.6	4.6	-1.3	-0.1	-0.4	0.5	-0.2	-0.4	-0.2	-0.1	-0.3	0.1	-0.2	-0.2	-0.4	-0.3	-1.0	-0.9	-2.1	0.1	-0.0	-1.3	-1.1
Fractured/broken bones in last 5 years	0.3	0.4	4.0	-0.1	-0.2	-0.9	-0.4	0.1	-0.1	-0.3	0.5	-0.7	-1.1	-0.5	-0.5	-0.3	-0.4	2.0	0.2	0.6	-0.2	0.2	-0.2	1.1
Age started oral contraceptive pill	3.6	4.5	9.8	1.4	2.6	3.1	2.8	-0.2	2.5	2.2	2.9	2.6	2.9	2.5	2.3	2.0	2.1	-0.9	1.5	1.5	-0.6	0.7	2.0	1.5
Diastolic blood pressure, automated reading	1.1	3.3	11.3	-0.9	1.1	1.3	0.9	-1.2	0.9	1.2	0.6	-0.4	1.5	1.4	1.5	1.9	1.3	-2.4	-2.4	3.2	-2.6	2.6	3.4	1.6
Ever depressed for a whole week	0.5	0.6	1.6	-0.9	-0.7	-1.1	-0.1	-1.1	-1.1	-0.9	0.8	-0.4	-0.7	-1.1	-1.2	-0.1	-0.8	0.5	-0.8	0.2	-0.6	-1.1	0.0	-0.6
Unable to work because of sickness or disability	1.8	2.4	4.8	-0.5	1.9	1.1	0.9	-1.7	1.3	1.8	0.0	1.5	1.5	1.4	1.5	2.1	1.9	-0.1	0.3	2.2	-1.2	2.1	1.9	2.2
Commuting to job workplace: Cycle	0.6	0.8	4.3	-0.7	-0.3	-0.4	-0.7	0.7	-0.0	-0.3	-1.9	-0.5	-0.5	-0.2	0.0	-0.8	-0.3	-1.5	-0.8	-2.1	-0.6	0.5	-1.3	-0.2
Myopia	0.7	1.0	10.8	-3.3	-0.1	-1.0	0.0	-0.3	-0.5	-0.5	0.4	0.1	-0.5	-0.6	-0.7	-0.3	-0.4	0.1	-1.6	-0.3	-2.2	-0.5	-0.2	-0.1
Vascular/heart problems diagnosed by doctor	1.1	2.9	6.4	0.5	-2.2	-1.5	-1.2	1.4	-1.6	-1.9	-1.2	-1.1	-1.7	-1.8	-2.0	-1.8	-1.9	1.8	-0.0	-1.7	2.5	-1.5	-1.8	-2.4
Cholesterol lowering medication	1.5	2.2	4.5	0.7	1.7	2.0	0.7	-0.4	1.8	1.7	1.4	1.7	1.9	1.9	1.3	1.8	1.7	-0.5	0.9	2.0	-0.7	1.1	2.1	1.3
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.9	0.6	0.5	0.5	-0.3	-0.4	0.8	0.7	-1.3	0.5	0.3	0.8	0.4	0.9	0.8	0.2	-0.1	0.6	0.2	1.4	0.8	0.5
Pain experienced in last month	0.5	0.9	3.2	-1.0	-1.0	-0.7	-0.0	0.5	-1.1	-1.1	1.1	-0.1	-0.3	-1.1	-0.6	-1.4	-1.1	-0.7	0.3	-1.0	1.0	-1.8	-1.2	-1.0
Supplements: Calcium	0.1	0.1	0.4	0.7	-0.5	0.1	-0.1	-0.3	-0.4	-0.4	-0.4	-0.4	0.1	-0.1	-0.2	-0.5	-0.4	-0.3	-0.4	0.1	0.2	-0.2	-0.0	-0.1
Basal cell carcinoma (self-reported)	0.5	0.6	2.9	-0.9	0.3	0.1	0.1	0.4	0.1	0.2	-0.3	-0.4	-0.1	0.2	0.2	0.2	0.2	-1.7	-1.2	0.8	-1.7	1.1	0.7	1.4
Heart attack/myocardial infarction (self-reported)	2.5	3.2	7.2	1.6	2.3	1.9	2.0	-1.6	1.2	2.0	2.7	2.0	2.1	1.8	1.7	1.9	2.0	0.4	1.4	2.1	-0.9	1.0	1.7	1.7
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.9	0.4	0.3	0.3	0.3	0.6	0.5	0.6	-0.2	0.2	-0.1	0.8	0.4	0.6	0.6	0.7	1.7	0.5	1.4	0.7	0.5	-0.3
Heart disease (siblings)	0.2	0.2	0.8	-0.8	0.4	0.3	0.3	-0.9	0.3	0.1	0.5	0.7	0.1	0.4	-0.2	0.1	-0.0	-0.7	-0.6	0.4	-0.4	0.3	0.6	0.6
Alcohol drinker status: Previous	0.8	0.9	2.0	1.0	1.2	0.8	0.8	-0.2	1.4	1.3	0.6	0.8	0.9	1.1	0.9	1.3	1.4	0.2	1.2	1.1	0.4	0.6	1.1	0.4
Pack years of smoking	0.4	0.6	3.1	-1.1	0.1	-0.5	0.5	-1.0	-0.0	-0.2	-1.8	-0.7	-0.7	-0.7	-0.5	0.4	-0.2	0.4	-1.2	0.3	-0.9	1.3	0.1	1.0
Impedance of whole body	0.2	1.0	2.6	-1.2	-0.3	-1.1	-0.8	1.1	-0.7	-0.7	0.2	0.4	-1.4	-0.8	-1.5	-1.2	-0.7	1.3	0.6	-1.2	-0.5	-1.3	-1.6	0.6
Leg fat mass (left)	0.7	2.8	9.2	0.9	1.5	1.6	0.3	-3.0	1.3	1.6	2.0	1.2	2.4	1.5	2.4	2.1	1.7	-1.2	-0.8	1.9	-1.0	1.1	2.4	0.2
Arm predicted mass (left)	0.6	3.0	8.1	1.8	-2.5	-1.7	-1.6	0.2	-1.4	-1.9	-2.4	-2.8	-1.0	-2.0	-1.2	-1.4	-1.8	0.4	-0.3	-0.7	2.8	-0.9	-1.0	-2.6