Hub : Genes

SH2D6

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.1019	0.0267	2.6e-08	0.084	0.079	0.126	0.108	0.140	5.9e-11	2.2e-10	7.7e-16	9.3e-14	1.5e-17
2	TCGA	Bladder Urothelial Carcinoma	0.0380	0.0230	8.0e-03	0.017	0.009	0.021	NA	0.026	1.3e-02	5.4e-02	6.7e-03	NA	2.6e-03
3	TCGA	Breast Invasive Carcinoma	0.0508	0.0192	6.4e-08	0.056	0.047	0.050	NA	0.052	1.2e-11	7.0e-10	1.6e-10	NA	8.2e-11
4	TCGA	Brain Lower Grade Glioma	0.0668	0.0255	2.7e-05	0.065	0.051	0.063	NA	0.064	7.0e-08	1.7e-06	1.1e-07	NA	9.3e-08
5	TCGA	Liver Hepatocellular Carcinoma	0.2140	0.0750	1.9e-04	0.078	0.089	0.173	NA	0.175	1.6e-04	5.7e-05	1.5e-08	NA	1.2e-08
6	TCGA	Lung Adenocarcinoma	0.1154	0.0429	3.3e-07	0.086	0.073	0.086	NA	0.085	3.1e-10	6.9e-09	3.1e-10	NA	3.4e-10
7	TCGA	Prostate Adenocarcinoma	0.0489	0.0275	6.3e-03	0.014	0.025	0.010	NA	0.008	1.3e-02	1.1e-03	2.9e-02	NA	4.6e-02
8	TCGA	Thyroid Carcinoma	0.0520	0.0290	7.7e-03	0.019	0.008	0.017	NA	0.014	5.5e-03	4.8e-02	7.9e-03	NA	1.4e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	3.3	5.2	16.6	2.3	-3.4	-1.5	1.0	0.6	-2.0	-0.8	4.1
Bipolar Disorder or Schizophrenia	2.1	5.1	9.7	2.8	-2.5	-1.9	2.0	-2.3	-1.9	-0.7	3.1
Depressed Affect (Nagel 2018)	4.0	8.5	18.9	-3.7	2.1	3.4	-2.2	2.5	2.8	4.3	0.5
Depression (Nagel 2018)	2.0	3.0	6.7	-2.6	1.5	1.7	-1.9	0.3	1.5	2.2	-1.1
Intelligence (Savage-Jansen 2018)	1.5	4.6	8.0	2.6	-2.8	-2.0	2.7	-1.9	-1.6	-2.0	1.2
Neuroticism (Nagel 2018)	2.5	5.9	13.0	-3.0	1.3	3.2	-1.7	1.4	3.0	3.6	0.5
Schizophrenia (2018)	1.3	2.7	11.5	1.8	-0.4	-1.2	2.0	-3.4	-0.9	-0.3	0.7
Schizophrenia vs Biploar Disorder	0.9	1.2	3.9	-0.5	2.0	0.6	0.4	-1.7	0.8	0.7	-1.0
Worry (Nagel 2018)	1.4	2.9	6.5	-1.9	1.4	2.1	-0.7	0.6	2.3	2.5	-0.7
Alzheimer’s Disease (in mother)	0.7	0.8	2.8	0.5	-1.0	-1.1	0.4	-0.8	-1.7	-0.5	0.1
Alzheimer’s Disease (in father)	2.0	2.2	6.4	1.3	-1.0	-1.9	-0.2	1.3	-2.5	-1.8	0.1
Alzheimer’s Disease (including proxy)	1.3	1.9	7.9	0.8	-1.1	-2.0	-0.4	0.7	-2.8	-0.8	0.6
Crohns Disease (2017)	0.2	0.5	1.4	0.1	-0.8	0.6	-0.3	0.8	0.3	1.2	0.7
Irritable Bowel Disease (IBD)	0.7	1.7	4.9	-0.8	-0.3	1.9	-0.2	0.6	1.9	2.2	-0.7
Ulcerative Colitis (UC)	2.2	4.2	9.1	-1.8	1.2	2.7	-0.4	0.5	3.0	2.8	-2.1
Major Depression (MDD)	0.7	0.9	1.9	-0.9	-0.4	0.9	-1.3	0.5	0.6	0.9	1.4
Reaction Time	1.0	1.9	4.1	-1.4	0.4	1.6	-1.2	2.0	1.7	1.4	-0.1
Verbal and Numeric Reasoning (VNR)	1.4	3.3	5.1	1.9	-1.9	-2.1	1.7	-1.7	-1.9	-2.3	0.4
Breast Cancer	0.6	1.5	7.6	-1.0	0.7	0.6	-0.1	-0.5	1.3	0.8	-2.8
Ovarian Cancer	0.7	0.9	1.6	1.3	-0.3	-1.2	0.6	-0.8	-1.2	-1.3	-0.6
Prostate Cancer	2.4	3.4	14.1	1.6	-0.9	-1.6	1.1	-0.5	-1.6	-1.7	3.8
Age at First Birth	0.8	1.1	3.2	0.7	-1.5	-0.2	-0.1	1.8	-0.8	-0.5	1.5
Bipolar Disorder (2011)	0.6	0.6	4.9	2.2	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.5	0.7	2.5	0.4	-0.8	-1.1	-0.2	0.0	-1.6	-0.3	-1.0
Coronary Artery Disease (CAD)	1.0	1.2	4.0	-0.8	0.3	1.1	-0.8	1.1	1.1	0.9	-2.0
Crohns Disease (2012)	0.4	0.6	1.5	-1.1	-0.1	0.9	-0.6	-0.2	1.0	1.2	0.3
Mean Putamen Volume	0.9	1.1	3.1	0.9	-1.8	0.2	1.2	-1.7	0.5	-0.3	-0.2
Fasting Glucose	0.6	0.7	2.2	0.5	-1.5	0.1	0.7	0.3	-0.1	0.8	1.5
HbA1C	1.1	1.2	2.7	1.7	-1.4	-1.2	1.1	-0.6	-0.9	-0.9	0.7
HDL Cholesterol	4.3	7.2	13.5	3.7	-1.3	-3.4	2.6	-1.9	-3.0	-3.2	1.1
LDL Cholesterol	0.4	0.6	2.3	0.3	-1.5	-0.3	0.9	-1.3	-0.0	0.2	-0.2
Lupus	0.9	1.4	3.5	-1.9	1.1	1.0	-1.5	0.9	0.8	1.3	0.5
Neuroticism (2016)	0.9	1.3	2.3	-1.1	1.2	1.2	-0.9	0.8	0.9	1.5	-1.4
Primary Biliary Cirrhosis	0.5	0.7	1.5	0.2	-1.2	-0.2	-1.0	1.1	-0.3	-1.2	0.1
Rheumatoid Arthritis	1.0	1.4	3.0	-0.6	1.4	1.4	0.4	-0.8	1.7	1.4	-1.0
Schizophrenia (2014)	2.6	5.7	18.6	2.9	-1.5	-2.0	2.9	-4.3	-1.4	-0.3	1.6
Triglycerides	0.5	0.8	2.0	1.0	-1.1	-0.8	1.0	-1.4	-0.7	-0.4	-0.0
Type 2 Diabetes (T2D) (2012)	1.3	1.5	4.0	0.1	-1.2	-1.5	-1.0	0.5	-2.0	-0.9	1.4
Ulcerative Colitis	0.6	0.8	2.7	-0.3	-0.0	1.1	0.5	-0.2	1.6	0.4	-1.4
Blood Eosinophil Count	0.4	2.7	6.5	1.6	-1.7	-0.5	2.5	-1.3	0.7	-1.3	2.4
Blood Platelet Count	4.3	49.3	82.8	9.1	-7.0	-7.6	7.8	-6.4	-7.5	-6.0	3.4
Blood Red Count	0.1	1.2	2.9	-1.2	-0.4	0.9	-0.7	-1.1	1.4	1.7	-0.2
Blood White Count	2.8	20.7	40.8	-5.9	4.7	5.8	-3.8	1.7	6.4	3.6	-2.0
Heel T-Score	0.1	0.8	3.5	0.6	-0.1	-1.3	0.8	-0.2	-0.5	-1.9	0.0
BMI	0.4	2.6	8.2	1.2	-0.4	-1.9	1.8	-2.9	-1.6	-0.9	-0.7
Height	0.3	5.8	12.7	1.6	-2.5	-3.6	0.1	-1.7	-3.5	-3.0	-0.9
Waist Hip Ratio (WHR)	0.7	3.1	6.5	-2.2	0.2	2.1	-2.5	1.4	2.3	1.1	0.6
Systolic Blood Pressure	0.2	0.9	1.7	1.3	-1.3	-0.7	1.0	0.9	-0.4	-1.2	0.1
Smoking Status	1.5	3.6	8.2	-2.9	1.6	2.1	-2.0	2.0	1.6	1.7	-0.7
Allergy or Eczema	1.2	3.2	6.8	2.4	-1.1	-2.2	1.9	-1.0	-1.6	-2.6	0.3
Cardiovascular Disease	0.6	2.1	6.5	1.0	-0.7	-1.7	0.2	-0.1	-1.5	-2.6	1.8
Hypothyroidism (self reported)	1.3	2.9	9.7	-1.7	0.9	0.2	-3.1	2.0	0.0	-1.9	-1.4
Respiratory disease	4.9	10.9	23.4	4.4	-2.0	-3.7	4.8	-3.1	-2.6	-3.1	0.1
Type 2 Diabetes (T2D) (2018)	0.7	1.3	4.6	-0.8	2.1	-0.4	-0.8	1.0	-0.2	-1.7	0.1
Lung FEV1/FVC ratio	1.7	8.4	20.1	-3.9	4.5	2.8	-2.9	1.6	2.4	2.2	-1.5
Lung FVC	0.1	0.4	1.1	-0.0	0.7	-0.5	-0.3	0.9	-0.3	-0.4	-1.0
Neuroticism	2.9	7.0	13.1	-3.6	2.2	2.8	-2.5	2.3	2.5	3.5	-0.1
Chronotype (morning person)	0.4	1.0	4.1	-0.5	0.4	0.6	-1.2	2.0	0.3	0.4	1.3
Hair Pigment	0.0	1.0	4.2	-0.4	1.1	-0.2	0.2	-1.5	0.2	0.5	-2.0
Tanning	0.2	2.2	5.2	1.3	-2.3	-1.6	0.7	1.1	-1.9	-0.7	1.6
Hand grip strength (left)	0.6	1.6	3.3	1.3	-1.0	-1.6	0.8	-1.1	-1.5	-1.8	-0.3
Number of treatments/medications taken	0.1	0.3	0.8	-0.6	0.9	0.2	-0.4	-0.2	0.2	0.3	0.8
Average weekly spirits intake	0.3	0.4	1.7	-0.6	-0.1	0.4	-0.8	0.6	-0.1	1.3	-0.2
Sensitivity / hurt feelings	0.4	0.7	2.2	-0.5	0.9	1.1	0.2	0.1	1.5	1.0	-0.4
Frequency of depressed mood in last 2 weeks	1.1	1.5	3.0	-1.6	1.6	1.2	-1.5	0.3	0.6	1.7	-0.3
Hearing difficulty/problems: Yes	0.7	1.1	4.9	-0.9	-0.3	0.6	-1.4	2.2	0.3	0.1	0.9
Relative age of first facial hair	1.4	2.9	4.6	-2.0	0.8	1.6	-1.7	2.1	1.3	1.7	-1.9
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.9	-0.7	1.4	0.5	-1.0	1.3	0.3	-0.4	-0.2
Ever used hormone-replacement therapy (HRT)	0.8	1.0	1.6	1.1	-1.0	-1.3	0.7	-0.5	-1.0	-1.2	0.9
Ever had hysterectomy (womb removed)	1.0	1.2	6.3	1.1	-0.3	-1.0	0.6	0.0	-0.5	-2.5	-0.6
Systolic blood pressure, automated reading	0.4	1.0	2.3	1.0	-0.9	-0.8	1.5	-0.2	-0.3	-1.1	-1.5
Eye problems/disorders: Diabetes related eye disease	3.7	4.0	11.1	1.4	-1.4	-3.1	0.9	0.5	-3.3	-2.2	1.5
Angina	0.5	0.7	3.6	-0.5	1.0	0.2	-0.6	0.0	0.1	-0.2	-1.9
Medication for hormone replacement therapy	1.1	1.2	1.8	1.3	-1.1	-1.3	1.2	0.0	-1.2	-1.1	0.9
Vitamin and mineral supplements	0.9	1.2	3.4	0.4	-0.1	-1.6	0.3	-1.1	-1.4	-1.9	-0.0
Supplements: Zinc	3.8	4.2	9.7	2.9	-1.4	-2.5	1.8	-0.1	-2.0	-3.1	0.5
Medication: Co-codamol	1.4	1.7	3.6	-1.9	1.2	1.3	-1.8	0.7	1.3	0.7	-0.8
Medication: Metformin	0.6	0.9	3.0	0.6	0.1	-1.0	0.1	0.6	-1.2	-1.1	1.7
Diabetes (father)	0.9	1.1	3.4	0.4	1.2	-1.1	0.9	-1.8	-1.1	-0.3	0.4
Diabetes (mother)	0.8	1.0	3.0	-1.3	1.0	-0.7	-1.7	0.6	-0.9	-0.6	0.1
Severe depression (siblings)	2.0	2.2	5.0	0.6	-1.3	-1.9	0.6	-1.8	-2.2	-0.5	1.8
Pack years adult smoking proportion	3.7	5.6	13.1	-2.4	1.1	3.0	-2.1	2.4	2.2	3.6	1.0
Impedance of leg (right)	0.3	1.5	4.6	-1.4	1.6	0.1	-0.9	0.4	1.2	-0.5	-2.1
Leg fat-free mass (left)	1.0	5.1	10.3	2.2	-2.5	-2.9	1.4	-1.9	-3.2	-2.4	-0.3
Trunk fat percentage	1.6	6.4	12.2	2.2	-0.0	-2.4	2.9	-3.2	-1.4	-2.8	-3.5
Hand grip strength (right)	0.7	1.8	3.2	1.4	-1.0	-1.6	1.1	-1.4	-1.4	-1.8	-0.4
Townsend deprivation index at recruitment	1.1	1.6	5.0	-1.3	1.1	1.0	-0.9	0.7	1.4	0.7	-2.2
Current tobacco smoking	5.5	9.0	15.9	-4.0	3.2	3.2	-2.6	2.6	2.7	3.9	-0.4
Average weekly fortified wine intake	2.7	3.2	7.4	1.3	-1.9	-2.5	0.5	-0.7	-2.7	-1.1	2.1
Maternal smoking around birth	1.3	1.9	3.1	-1.1	0.9	1.8	-1.4	1.7	1.7	-0.0	-1.4
Fed-up feelings	3.2	5.9	11.9	-3.5	2.2	2.5	-2.5	1.1	2.4	3.3	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.9	3.8	6.9	-2.5	2.4	1.8	-1.7	0.3	1.4	2.6	-1.8
Relative age voice broke	0.8	1.2	2.5	-1.2	0.9	1.2	-1.0	0.9	1.1	1.6	0.4
Taking other prescription medications	1.3	2.0	5.1	-1.5	2.3	1.0	-1.9	1.6	0.8	-0.3	-0.9
Age when periods started (menarche)	1.6	3.9	8.7	-1.9	1.8	2.4	-0.6	0.3	2.9	2.0	-2.5
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.6	0.3	-0.0	0.3	0.2	-0.1	0.2	-0.8	0.1
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.4	7.6	1.3	-0.3	-2.0	1.2	-0.9	-1.3	-2.8	1.3
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	3.0	0.2	0.6	-0.6	0.2	-1.7	-0.4	0.3	1.5
Qualifications: CSEs or equivalent	0.7	0.9	2.5	-0.9	1.6	0.6	-0.1	-0.2	1.0	1.3	-0.6
Serious illness, injury or assault to yourself	1.4	1.7	4.0	0.5	-0.9	-1.9	0.3	-2.0	-1.8	-0.9	1.0
High blood pressure	0.4	1.1	3.3	0.3	-0.5	-1.5	-0.2	0.4	-1.4	-1.8	0.9
Hayfever, allergic rhinitis or eczema	0.9	1.9	5.6	1.1	0.6	-2.0	1.0	-0.8	-1.6	-2.4	-0.1
Multivitamins +/- minerals	0.5	0.6	1.5	0.3	-0.6	1.2	0.0	0.4	1.2	1.2	0.1
Stomach or abdominal pain in last month	2.7	3.4	5.4	-2.2	2.3	2.3	-1.9	0.8	2.1	1.8	0.4
Supplements: Glucosamine	0.2	0.3	0.7	0.4	-0.8	-0.4	-0.2	-0.6	-0.5	-0.6	0.7
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.7	-0.4	0.1	0.7	-0.9	0.4	0.5	0.1	0.8
Medication: Atenolol	0.7	0.9	1.8	-0.9	0.6	1.3	-0.8	1.1	1.3	0.6	0.6
Medication: Levothyroxine sodium	1.1	1.9	8.1	0.0	-0.0	-1.5	-1.3	0.4	-1.4	-2.9	-0.9
Sitting height	0.7	5.3	12.4	2.0	-2.6	-3.2	1.2	-1.4	-3.5	-2.4	0.2
Chronic bronchitis/emphysema (father)	0.7	0.9	2.7	1.0	0.2	-1.4	1.6	-0.6	-0.8	-0.6	0.1
High blood pressure (mother)	0.9	1.2	7.1	0.3	0.5	-0.5	-0.7	0.6	-1.0	-0.7	2.7
Body mass index (BMI)	0.7	2.8	7.2	1.5	-0.1	-1.5	2.3	-2.7	-1.1	-0.8	-1.9
Impedance of leg (left)	0.5	2.5	5.5	-1.9	2.1	0.9	-1.2	0.8	1.8	-0.2	-2.4
Leg predicted mass (left)	1.0	5.5	10.8	2.3	-2.5	-3.0	1.5	-2.0	-3.3	-2.4	-0.3
Trunk fat mass	1.7	7.1	10.2	2.5	-0.9	-2.9	2.8	-3.1	-2.1	-3.1	-3.2
Waist circumference	0.7	2.5	5.2	1.3	-0.9	-1.8	1.6	-2.3	-1.4	-1.2	-1.8
Number of incorrect matches in round	0.6	1.0	2.3	0.8	-1.2	0.3	1.1	0.7	0.7	1.1	-1.5
Past tobacco smoking	0.8	1.5	3.0	1.0	0.2	-1.7	1.1	-1.1	-1.7	-0.6	1.4
Alcohol usually taken with meals	2.2	3.6	9.6	1.1	-1.6	-2.8	-0.2	-0.8	-3.1	-2.1	1.4
Nervous feelings	0.3	0.6	1.8	-1.1	1.4	0.6	-0.4	-0.0	0.9	0.9	0.4
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	3.7	-0.9	1.5	1.6	-0.2	-1.2	1.5	1.9	-0.5
Hearing difficulty/problems with background noise	0.7	1.2	3.1	0.9	-0.9	-1.2	-0.1	0.7	-1.1	-1.8	1.2
Hair/balding pattern: Pattern 2	0.5	0.6	1.4	0.6	-0.4	0.9	1.1	0.0	0.8	1.2	-0.6
Had menopause	0.2	0.3	1.4	0.0	0.6	0.3	0.5	0.3	0.5	0.3	-1.2
Had other major operations	1.0	1.3	4.5	1.1	-0.2	-1.4	0.6	0.2	-1.5	-2.1	0.2
Forced vital capacity (FVC)	0.3	1.2	3.3	1.1	-1.3	-0.8	0.4	0.3	-0.3	-1.5	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	1.3	3.0	6.8	1.4	-0.6	-2.1	1.5	-1.4	-1.5	-2.1	2.6
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	1.5	-0.5	-0.9	0.4	0.4	-1.2	0.6	1.0	-0.4
Qualifications: None of the above	0.9	2.0	3.8	-2.0	0.5	1.2	-1.6	1.5	1.0	1.7	-1.3
Financial difficulties in last 2 years	4.9	6.6	9.9	-2.6	2.7	3.0	-1.5	2.3	3.1	2.9	-2.1
Mouth/teeth dental problems	0.4	0.6	2.1	0.7	-0.3	-0.4	0.3	1.0	-0.1	-1.4	-0.9
Heart attack	0.2	0.3	0.6	0.5	-0.2	-0.5	0.4	0.1	-0.4	-0.8	-0.7
Allergy	1.7	3.9	6.9	-2.5	0.4	2.5	-2.6	2.0	2.0	2.0	-0.4
Pain all over the body in last month	1.1	1.1	4.5	-1.0	1.7	-0.0	-0.6	-0.4	0.2	0.4	-2.1
Diabetes (self-reported)	0.6	0.9	2.3	-0.2	0.7	-0.7	-0.5	1.5	-0.8	-1.0	1.4
Hayfever/allergic rhinitis (self-reported)	1.9	2.5	5.1	1.9	-1.5	-1.1	2.2	-1.7	-0.6	-1.5	1.4
Medication: Ramipril	2.5	3.2	10.4	1.6	-1.6	-2.2	0.5	0.0	-2.1	-3.2	0.6
Medication: Simvastatin	1.1	1.6	3.5	1.0	0.1	-1.9	0.8	-0.6	-1.8	-1.8	1.0
Fluid intelligence score	0.6	1.3	2.5	0.7	-1.6	-1.6	0.8	-1.2	-1.3	-0.8	0.1
Illnesses of siblings	0.5	0.7	3.1	-0.3	-0.9	-0.0	-1.0	0.7	-0.4	0.2	1.8
Neuroticism score	2.5	5.3	10.9	-3.3	2.6	2.1	-2.3	1.6	1.9	2.7	-0.6
Weight	1.1	5.4	8.2	2.1	-1.2	-2.8	2.1	-2.9	-2.5	-2.4	-2.1
Impedance of arm (right)	0.2	1.0	5.4	0.4	0.2	-0.9	0.1	0.0	-0.1	-2.3	-1.1
Arm fat percentage (right)	1.2	4.7	9.9	2.1	-0.3	-2.0	2.7	-3.1	-1.2	-1.8	-2.7
Trunk fat-free mass	0.7	4.3	9.5	1.5	-2.5	-2.7	0.8	-2.1	-3.1	-1.7	-0.2
Hip circumference	1.6	6.9	10.3	2.7	-1.6	-3.2	2.8	-3.1	-2.8	-2.3	-2.1
Time employed in main current job	0.4	0.4	1.5	-0.0	-0.5	1.2	-0.2	-0.3	1.0	0.8	0.2
Alcohol intake versus 10 years previously	0.5	0.7	1.3	-0.7	1.2	0.8	-0.8	0.7	1.1	0.8	0.2
Father’s age at death	0.7	0.9	2.3	0.5	-0.5	-0.7	-0.3	1.4	-1.1	-0.9	1.5
Worrier / anxious feelings	2.5	4.7	10.3	-2.1	1.3	2.8	-0.9	-0.4	3.2	3.1	-1.6
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	2.9	-1.7	1.4	1.2	-1.6	-0.2	1.2	1.1	-0.4
Falls in the last year	1.2	1.6	4.6	-1.1	2.1	1.3	-0.9	0.7	1.4	1.3	-0.4
Hair/balding pattern: Pattern 3	0.5	0.7	2.2	-1.1	1.5	0.2	-0.1	-1.0	0.6	0.6	-0.7
Number of live births	1.0	1.5	2.9	-1.7	1.0	1.3	-0.9	-0.4	1.5	1.4	-1.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	4.2	-0.2	-0.1	-0.1	-0.6	0.9	0.4	-1.0	-2.0
Pulse rate	0.6	1.0	2.3	-1.5	1.2	0.7	-0.3	-1.1	1.3	0.8	-0.5
Happiness	0.5	0.6	1.3	-0.4	0.6	0.8	-0.3	-1.1	0.8	0.9	1.0
Noisy workplace	0.1	0.2	0.5	-0.6	-0.2	-0.1	-0.6	-0.1	0.0	-0.2	0.7
Qualifications: A levels/AS levels or equivalent	1.3	2.8	7.3	1.7	-0.7	-1.4	1.5	-1.1	-1.4	-2.0	2.7
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	2.8	0.7	-1.6	-1.4	0.0	1.4	-1.6	-1.7	0.4
Mouth/teeth dental problems: Dentures	0.5	0.9	3.2	-0.8	0.8	0.8	-0.6	-0.7	0.5	1.8	-0.8
Asthma	1.1	2.2	6.0	2.0	-0.4	-1.3	2.5	-2.2	-0.6	-0.9	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	1.5	-0.6	0.5	0.8	-1.0	0.3	0.3	1.2	1.1
Medication: Cholesterol lowering	0.3	0.5	1.2	0.5	-0.7	-0.7	-0.0	0.2	-0.9	-1.1	0.7
Depression (self-reported)	1.4	1.7	5.0	-1.8	1.6	0.6	-2.2	1.5	0.0	0.2	0.1
Medication: Lansoprazole	1.7	1.9	5.0	-1.1	1.5	1.9	-0.4	-0.1	2.2	1.5	-0.3
Prospective memory result	4.3	5.3	15.5	2.1	0.7	-3.0	1.4	-2.4	-2.4	-3.9	0.4
Lung cancer (father)	0.7	0.8	1.6	-1.3	-0.2	0.8	-0.6	0.6	1.0	1.1	0.9
Illnesses of mother	0.7	0.8	2.1	-0.2	-0.5	0.8	0.5	-1.0	1.1	1.1	-1.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	4.1	0.3	0.1	-1.0	-0.0	0.0	-0.3	-2.0	-1.9
Pulse wave Arterial Stiffness index	2.7	3.2	7.1	2.3	-0.9	-1.6	2.7	-2.0	-1.6	-1.2	1.2
Impedance of arm (left)	0.2	0.9	4.8	0.3	1.0	-1.0	0.2	0.0	-0.2	-2.2	-0.6
Arm fat mass (right)	1.2	4.7	8.0	2.1	-0.8	-2.3	2.6	-2.8	-1.7	-2.0	-2.5
Trunk predicted mass	0.7	4.0	9.0	1.5	-2.5	-2.7	0.7	-2.1	-3.0	-1.7	-0.2
Standing height	0.7	6.5	15.4	1.7	-2.8	-3.5	0.4	-1.3	-3.4	-3.9	-1.0
Length of working week for main job	0.6	0.6	1.7	-0.6	0.4	-0.6	-1.3	1.0	-0.9	-0.6	0.3
Exposure to tobacco smoke at home	3.7	4.1	7.2	-1.8	2.0	2.5	-1.3	1.5	2.3	1.7	-2.7
Breastfed as a baby	1.0	1.3	3.2	0.5	-1.5	-1.4	-0.6	-0.2	-1.8	-1.2	1.1
Tense / ‘highly strung’	0.6	0.9	2.4	-1.2	1.6	0.6	-1.1	1.3	0.2	0.6	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.9	-0.5	1.0	0.1	-0.3	-0.0	-0.2	1.0	0.9
Hair/balding pattern: Pattern 4	0.6	1.4	8.0	0.4	-0.3	-0.7	-0.5	0.2	-1.4	-0.1	2.8
Birth weight of first child	0.6	1.0	3.8	0.8	-0.8	-0.3	1.4	-1.9	-0.2	0.2	0.8
Peak expiratory flow (PEF)	0.5	1.2	4.7	1.1	-1.1	-1.2	0.5	0.3	-0.8	-2.2	0.5
Pulse wave reflection index	2.5	3.1	5.6	2.4	-1.8	-1.6	1.9	-1.6	-1.8	-1.2	1.6
Ever highly irritable/argumentative for 2 days	1.7	2.1	5.9	-1.6	2.4	1.5	-0.9	-0.0	1.7	1.2	-0.9
Loud music exposure frequency	1.0	1.1	2.3	-0.9	1.5	-0.7	-1.3	1.0	-1.0	-0.5	1.1
Qualifications: O levels/GCSEs or equivalent	3.7	5.8	10.9	2.8	-0.7	-2.7	2.5	-2.9	-2.0	-3.3	1.3
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.5	-0.2	0.7	-0.5	0.0	-0.4	-0.4	0.3	0.2
Blood clot in the leg (DVT)	0.6	0.7	1.8	0.9	-0.6	-0.8	1.3	-0.1	-0.8	-0.1	1.3
Medication: Paracetamol	0.7	1.2	3.4	-0.2	1.5	0.5	0.6	-1.4	0.9	0.7	-1.9
Headache pain in last month	0.8	1.3	2.5	-1.2	0.4	1.2	-1.1	-0.8	1.6	1.2	1.2
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	3.9	-0.6	1.1	1.1	0.0	0.1	1.4	1.3	-2.0
Glaucoma (self-reported)	1.8	2.1	6.2	-1.3	0.3	1.2	-2.4	2.5	0.4	0.9	1.0
Gout (self-reported)	1.6	2.2	4.1	-2.0	1.7	1.2	-1.8	1.0	1.2	1.0	-1.4
Hypothyroidism/myxoedema (self-reported)	1.3	2.5	7.0	-1.1	0.5	-1.0	-2.5	1.5	-0.9	-2.6	-1.1
Medication: Amlodipine	1.2	1.7	11.1	0.5	0.1	-0.7	0.0	0.1	-1.2	-0.3	3.3
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.8	0.5	0.1	-0.8	0.9	-1.3	-0.5	0.0	-0.2
Birth weight	0.3	0.8	1.5	0.7	-1.0	-1.0	0.3	-0.7	-1.2	-0.1	1.2
Chronic bronchitis/emphysema (mother)	0.5	0.6	3.8	0.0	0.3	-0.7	0.0	-0.2	-0.3	-1.9	0.6
High blood pressure (siblings)	0.5	0.7	2.4	-0.3	1.6	0.8	0.5	-0.5	1.1	0.2	-1.0
Forced vital capacity (FVC), Best measure	0.7	2.4	6.4	1.6	-1.1	-1.9	1.0	-0.5	-1.2	-2.5	-1.5
Body fat percentage	1.4	5.3	13.0	1.8	0.4	-2.1	2.6	-3.0	-1.1	-2.4	-3.6
Leg fat percentage (right)	1.3	4.6	13.8	1.3	0.3	-2.1	2.1	-2.8	-1.1	-1.9	-3.7
Arm fat-free mass (right)	0.5	2.4	6.0	1.0	-1.3	-2.1	0.9	-1.6	-2.4	-1.3	-0.9
Exposure to tobacco smoke outside home	1.3	1.8	3.3	-1.8	1.3	1.4	-1.1	0.5	1.5	1.8	-0.1
Comparative body size at age 10	0.4	1.1	2.5	1.4	-1.3	-1.0	0.4	-0.2	-1.6	-1.1	0.3
Number of full brothers	0.5	0.7	1.8	0.6	-0.0	-1.0	0.7	-1.4	-1.1	-0.8	-0.0
Worry too long after embarrassment	0.5	0.9	2.1	-1.5	1.1	0.7	-1.3	0.1	0.7	0.9	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	1.2	0.8	0.6	-0.8	0.7	-0.6	-1.1	-0.7	0.6
Wheeze or whistling in the chest in last year	0.3	0.5	1.4	-0.0	0.7	-0.3	0.9	-1.0	0.4	-0.4	-1.2
Number of children fathered	0.4	0.5	1.3	0.8	-0.9	-0.4	1.1	-0.9	-0.2	0.1	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.3	6.1	0.9	-1.4	-0.5	0.8	-2.5	0.1	-0.1	0.8
Age at first live birth	0.8	1.5	6.1	1.1	-1.0	-0.6	0.2	1.3	-1.0	-0.7	2.5
Pulse wave peak to peak time	2.3	2.7	6.5	-2.1	0.6	1.3	-2.6	2.0	1.4	0.9	-1.3
Health satisfaction	0.4	0.5	2.3	0.5	0.5	-0.4	0.7	-1.5	-0.2	-0.7	-0.0
Shortness of breath walking on level ground	1.4	1.6	8.0	-1.0	2.8	0.9	-0.4	-0.4	1.1	0.7	-1.2
Qualifications: College or University degree	1.4	4.3	6.4	2.4	-2.3	-2.2	1.4	-0.8	-2.1	-2.5	2.3
Eye problems/disorders: None of the above	1.5	1.7	6.1	-0.2	1.1	0.8	0.7	-1.6	1.5	0.8	-2.5
Mouth/teeth dental problems: Loose teeth	0.5	0.5	1.5	-1.2	0.6	0.4	-0.5	0.0	0.5	1.1	-0.7
Emphysema/chronic bronchitis	1.8	2.1	4.0	2.0	-2.0	-1.4	1.4	-0.1	-1.7	-1.1	0.8
Medication for pain relief, constipation, heartburn	0.2	0.4	1.1	-0.1	-1.0	0.5	0.0	1.0	0.4	0.1	0.7
Neck or shoulder pain in last month	0.8	1.1	3.6	-0.5	0.2	1.3	0.0	-0.5	1.4	1.9	1.1
Medication: Blood pressure	0.5	0.8	3.7	0.5	-0.6	-0.6	0.0	0.7	-0.8	-1.0	1.9
Angina (self-reported)	0.4	0.5	3.1	-0.2	0.7	0.0	-0.2	-0.3	-0.1	-0.2	-1.8
Migraine (self-reported)	2.6	3.3	6.4	-1.5	1.6	2.1	-1.7	1.4	2.1	1.0	-2.5
Medication: Ibuprofen	0.7	0.8	2.7	-0.6	0.2	1.3	-0.4	-0.0	1.2	1.6	0.6
Medication: Allopurinol	3.7	4.9	8.4	-2.9	2.7	2.2	-2.3	1.1	2.2	1.3	-2.4
Medication: Omeprazole	0.5	0.6	1.1	-0.7	1.1	-0.8	-1.0	-0.2	-1.0	-0.8	0.1
Medication: Seretide 50 evohaler	1.7	2.0	6.5	2.5	-0.7	-0.3	2.6	-1.2	-0.2	-0.8	0.6
Mean time to correctly identify matches	0.5	1.0	1.5	-1.1	0.7	1.1	-0.8	1.2	1.1	1.2	-0.0
Heart disease (mother)	1.1	1.3	5.7	0.4	0.9	-0.8	0.4	-1.1	-0.2	-1.4	-2.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.0	3.5	7.3	-2.3	1.6	1.7	-2.5	2.7	0.9	1.8	-0.5
Whole body fat mass	1.3	5.2	9.5	1.9	-0.6	-2.6	2.3	-2.6	-1.8	-2.5	-3.1
Leg fat mass (right)	1.2	4.7	9.1	1.7	-0.7	-2.4	2.2	-2.6	-1.7	-2.1	-3.0
Arm predicted mass (right)	0.4	2.2	5.7	1.0	-1.4	-2.0	0.8	-1.5	-2.4	-1.2	-0.8
Pulse rate, automated reading	0.1	0.5	1.6	-1.0	0.0	0.5	-0.2	-0.8	1.3	0.2	0.3
Alcohol intake frequency.	0.3	0.7	1.3	-1.1	0.8	0.8	-0.6	0.4	1.2	0.9	0.9
Comparative height size at age 10	0.5	2.7	7.3	1.7	-1.7	-1.9	0.6	-1.3	-1.6	-2.7	-0.9
Number of full sisters	0.9	1.0	3.3	-1.6	1.5	0.0	-1.8	0.4	-0.4	-0.1	0.0
Suffer from ‘nerves’	0.4	0.7	2.4	-1.1	1.6	-0.7	-0.2	-0.6	-0.3	-0.2	-0.7
Overall health rating	0.7	1.5	3.4	-1.3	1.5	1.3	-0.3	-0.2	1.6	1.9	-0.1
Chest pain or discomfort	0.2	0.3	0.8	-0.5	0.6	-0.2	-0.9	-0.7	-0.5	0.0	-0.3
Had major operations	3.3	3.8	7.2	2.7	-1.4	-2.1	1.6	-1.6	-2.5	-1.9	1.4
Age at last live birth	0.6	0.9	1.8	0.8	-1.4	-0.5	0.1	0.9	-0.5	-1.2	1.3
Family relationship satisfaction	0.4	0.5	2.7	-0.1	0.6	0.2	-0.3	-0.5	0.1	0.7	1.6
Leg pain on walking	1.8	2.3	8.4	-0.6	1.8	1.0	0.4	-1.3	1.8	0.5	-2.9
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.3	1.1	-0.7	0.3	0.9	-0.2	0.3	0.7	0.3
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.0	-1.1	0.0	1.1	-0.4	-0.0	1.1	1.4	-0.4
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.4	0.1	0.5	0.8	0.2	0.0	0.6	1.1	1.2
Medication: Aspirin	0.7	1.0	2.1	0.7	-0.1	-1.4	0.3	-0.9	-1.5	-1.2	0.9
Supplements: Vitamin C	0.7	0.8	2.8	0.6	-0.6	-1.5	-0.2	0.4	-1.7	-0.4	0.9
Knee pain experienced in last month	0.3	0.5	2.2	-0.3	0.8	-0.5	-0.6	-0.5	-0.1	-1.5	-0.3
Hypertension (Self-reported)	0.4	1.0	2.6	0.4	-0.7	-1.4	-0.1	0.0	-1.1	-1.6	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.0	-1.4	0.8	0.4	-0.7	-0.2	0.9	-0.3	-0.7
Illnesses of father: Heart disease	2.3	3.2	21.4	-1.1	0.9	0.5	-1.1	0.3	0.7	-0.0	-4.6
Illnesses of siblings: Diabetes	1.0	1.2	2.5	0.4	1.2	-1.6	0.3	-0.5	-1.6	-1.3	-0.9
Smoking status: Previous	0.7	1.1	4.8	-0.3	-1.0	0.8	-0.8	0.6	1.0	-0.4	-2.2
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	4.7	-0.7	-0.8	-1.0	-1.8	1.2	-1.2	-2.2	-0.1
Whole body fat-free mass	0.8	4.4	10.0	1.8	-2.5	-2.8	1.0	-2.0	-3.2	-1.9	-0.2
Leg fat-free mass (right)	0.7	4.0	8.1	2.0	-2.2	-2.5	1.2	-1.6	-2.9	-2.1	-0.1
Arm fat percentage (left)	1.2	4.9	10.3	2.0	0.1	-2.2	2.7	-3.2	-1.5	-2.0	-2.6
Average weekly red wine intake	6.8	10.1	17.8	3.3	-3.6	-4.2	2.2	-2.2	-4.2	-2.8	1.9
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.5	-0.2	-0.8	-0.3	-0.8	-0.1	-0.8	0.3	1.2
Mood swings	1.7	3.0	8.9	-1.9	1.8	2.0	-0.9	1.0	1.6	3.0	-0.2
Loneliness, isolation	2.0	2.8	5.2	-2.0	0.5	1.7	-2.1	2.0	1.1	2.3	-0.2
Long-standing illness, disability or infirmity	0.8	1.2	5.5	0.9	0.1	-1.3	-0.2	-0.3	-1.2	-2.4	0.5
Ever had bowel cancer screening	2.6	3.1	6.6	2.6	-1.8	-0.8	2.4	-1.7	-0.6	-1.2	2.0
Diabetes diagnosed by doctor	0.5	0.8	1.8	-0.3	0.5	-0.9	-0.7	0.7	-0.9	-1.2	1.4
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	0.7	-0.8	-0.7	0.8	-0.2	0.7	0.7	0.8	-0.3
Friendships satisfaction	0.8	1.0	3.5	0.6	0.5	0.8	0.9	-1.9	1.0	1.0	0.4
Qualifications: nursing, teaching	1.3	2.0	4.3	1.5	-0.8	-1.9	0.6	-1.5	-2.1	-1.2	1.1
Commuting to job workplace: Walk	0.3	0.4	1.0	-0.2	0.7	-0.2	-0.7	1.0	-0.7	-0.2	0.5
Eye problems/disorders: Cataract	3.4	3.9	12.5	2.0	-0.8	-1.8	1.4	0.4	-2.1	-2.1	3.5
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	3.1	-1.6	0.4	0.5	-1.8	1.1	-0.4	0.5	1.1
Medication for cholesterol	0.7	1.1	1.7	-1.2	0.1	1.3	-1.2	0.5	1.0	1.3	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.4	4.5	-0.5	2.0	0.3	0.4	-0.9	1.0	0.3	-2.1
Back pain experienced in last month	0.5	0.7	2.1	-1.1	1.4	0.3	-0.8	-0.5	0.3	0.5	-1.0
Mineral and other dietary supplements	0.4	0.6	1.9	-0.8	1.4	0.7	-0.3	0.8	0.6	0.6	-0.5
Breast cancer (self-reported)	2.0	2.4	9.2	0.8	-3.0	-1.8	-0.1	-1.1	-2.0	-1.1	0.0
Asthma (self-reported)	1.7	3.5	8.4	2.4	-0.9	-1.9	2.9	-2.4	-1.2	-1.4	-0.1
Osteoporosis (self-reported)	0.3	0.3	1.2	-0.6	0.5	0.3	0.3	-0.1	0.6	1.1	0.3
Osteoarthritis (self-reported)	0.6	0.8	2.0	0.6	0.6	-1.3	-0.0	-0.8	-1.4	-1.1	-0.1
Medication: Aspirin	0.9	1.2	2.0	1.1	-0.2	-1.4	0.9	-1.1	-1.4	-1.3	0.8
Medication: Gliclazide	0.4	0.5	1.5	-0.8	0.4	0.5	-0.3	1.2	0.2	0.9	0.7
Illnesses of father: None of the above (group 1)	0.4	0.5	0.8	-0.7	0.1	0.7	-0.7	-0.9	0.8	0.8	0.7
Smoking status: Current	4.7	7.5	13.3	-3.7	3.3	2.9	-2.2	2.3	2.4	3.3	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.5	2.0	0.5	0.6	-1.1	0.4	-0.3	-0.5	-1.4	-0.2
Whole body water mass	0.8	4.4	10.2	1.8	-2.3	-2.8	1.1	-1.9	-3.2	-1.9	-0.3
Leg predicted mass (right)	0.8	4.0	8.1	2.0	-2.3	-2.5	1.3	-1.6	-2.9	-2.1	-0.1
Arm fat mass (left)	1.2	4.9	9.3	2.0	-0.6	-2.5	2.5	-3.0	-1.9	-2.0	-2.4
Number of self-reported non-cancer illnesses	1.7	2.9	9.4	0.9	0.2	-2.5	0.3	-0.8	-2.4	-3.1	0.4
Average weekly champagne plus white wine intake	3.5	4.8	9.2	2.0	-1.0	-2.8	0.6	-2.2	-2.6	-3.0	2.1
Miserableness	3.6	6.3	12.0	-3.5	2.3	2.6	-2.9	2.7	1.9	2.7	-0.1
Guilty feelings	1.4	2.1	4.9	-1.9	2.2	1.0	-2.1	0.7	0.9	0.9	-0.8
Wears glasses or contact lenses	0.9	1.1	1.5	-1.0	1.2	1.1	-1.1	1.0	0.6	1.2	0.7
Ever taken oral contraceptive pill	1.8	2.0	4.5	-0.7	-0.7	1.6	-1.3	1.9	1.3	0.7	2.1
Hearing aid user	0.4	0.4	1.0	0.6	0.0	-0.3	1.0	0.6	-0.3	-0.6	0.9
Mother’s age at death	0.4	0.5	1.8	-0.5	1.2	0.1	-0.1	0.2	-0.2	0.8	-1.3
Financial situation satisfaction	6.0	7.4	15.4	-2.7	2.9	3.8	-1.2	0.5	3.9	3.1	-1.6
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.7	-0.9	1.6	0.3	-0.8	0.7	0.5	-0.5	-1.4
Commuting to job workplace: Public transport	0.4	0.4	1.0	0.6	-1.0	-0.3	0.2	-0.5	-0.3	-0.8	1.0
Eye problems/disorders: Glaucoma	2.3	2.7	8.1	-1.5	0.8	1.3	-2.6	2.8	0.7	0.7	1.0
Medication: Blood pressure	0.1	0.2	0.9	-0.0	0.9	-0.3	-0.0	-0.5	-0.2	-0.4	0.3
Pain type(s) experienced in last month: Hip pain	1.1	1.4	6.3	0.2	2.5	-0.6	0.9	0.1	-0.3	-1.1	-1.4
Supplements: Fish oil (including cod liver oil)	0.2	0.3	1.0	0.3	-1.0	-0.4	-0.3	-0.0	-0.7	-0.3	0.4
High cholesterol (Self-reported)	1.4	2.6	5.9	1.1	-0.6	-2.4	0.6	0.2	-2.4	-2.3	1.3
Medication: Bendroflumethiazide	0.2	0.3	0.6	-0.5	-0.2	0.4	-0.8	0.8	0.3	0.2	0.5
Medication: Paracetamol	0.7	1.0	2.8	0.1	1.2	0.3	1.0	-1.3	0.9	0.4	-1.7
Medication: Lisinopril	0.3	0.4	2.3	0.1	0.8	-0.3	0.1	0.1	-0.1	-0.5	1.5
Medication: Atorvastatin	1.1	1.3	4.9	1.5	-2.2	-0.6	1.2	-1.0	-0.5	-0.5	0.5
Illnesses of father: High blood pressure	1.1	1.3	2.7	1.2	-0.3	-1.4	1.0	-0.4	-1.5	-1.6	0.8
Alcohol drinker status: Never	1.4	1.7	5.4	-0.6	1.2	1.3	0.9	-1.2	1.4	2.3	-0.2
Ever smoked	0.5	0.8	1.6	-0.7	-0.5	1.2	-1.1	1.3	1.1	0.6	-0.4
Basal metabolic rate	0.8	4.6	8.9	1.9	-2.2	-2.8	1.4	-2.3	-3.0	-2.1	-0.8
Leg fat percentage (left)	1.1	4.1	14.4	1.2	0.5	-1.7	2.0	-2.5	-0.7	-1.8	-3.8
Arm fat-free mass (left)	0.5	2.7	5.7	1.4	-1.8	-2.2	1.0	-1.5	-2.4	-1.5	-0.7
Number of operations (self-reported)	1.5	2.2	3.9	2.0	-0.8	-1.4	1.8	-1.6	-1.5	-1.7	-0.1
Average weekly beer plus cider intake	1.0	1.4	2.9	-1.7	0.8	1.2	-1.7	1.3	1.0	0.7	-0.6
Irritability	0.2	0.3	0.8	-0.5	0.2	0.9	-0.7	0.1	0.9	0.1	0.2
Risk taking	0.7	1.0	2.0	0.8	-1.1	-1.3	0.9	-0.1	-1.4	-0.9	0.9
Ever had prostate specific antigen (PSA) test	1.5	1.7	4.3	1.5	0.4	-1.0	1.9	-2.1	-1.0	-0.3	-1.2
Fractured/broken bones in last 5 years	2.2	2.9	5.6	-2.2	1.7	1.5	-1.9	1.7	0.7	2.4	0.9
Age started oral contraceptive pill	2.3	2.9	4.4	2.1	-2.0	-1.9	2.0	-0.6	-1.8	-1.4	1.1
Diastolic blood pressure, automated reading	1.0	2.9	13.1	-1.2	1.4	1.3	-0.3	0.6	2.2	-0.5	-3.6
Ever depressed for a whole week	0.5	0.6	1.6	-0.1	-1.1	-0.4	-0.2	-1.1	-0.5	0.4	1.3
Unable to work because of sickness or disability	0.4	0.5	0.8	0.4	0.5	-0.9	0.3	-0.9	-0.9	-0.9	0.1
Commuting to job workplace: Cycle	4.2	5.1	8.2	2.5	-1.6	-2.6	1.8	-1.1	-2.5	-2.6	2.9
Myopia	0.9	1.2	2.5	1.3	0.3	-1.2	1.4	-1.6	-1.1	-1.0	-0.5
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.2	-0.1	0.1	1.2	0.2	-0.4	1.0	1.5	-0.1
Cholesterol lowering medication	2.1	3.1	7.5	1.7	-0.3	-2.7	1.4	-0.5	-2.5	-2.3	0.7
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	2.7	-1.1	1.7	-0.3	-1.3	0.1	-0.4	-0.7	-1.0
Pain experienced in last month	0.1	0.1	0.3	0.1	-0.5	0.1	-0.1	0.3	-0.4	-0.2	0.4
Supplements: Calcium	2.6	2.9	4.4	2.1	-1.6	-2.1	1.6	-0.6	-1.9	-2.1	1.1
Basal cell carcinoma (self-reported)	3.7	4.4	7.8	2.7	-2.0	-2.6	2.8	-1.8	-2.2	-0.7	0.5
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.6	0.5	-0.4	-0.6	0.3	0.4	-0.5	-0.8	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	1.9	1.1	-1.0	-0.7	1.4	-0.3	-0.8	-0.2	1.1
Heart disease (siblings)	1.9	2.3	4.1	1.4	-0.7	-2.0	1.6	-1.3	-1.5	-1.5	-1.9
Alcohol drinker status: Previous	2.6	3.0	6.5	1.9	-1.8	-1.9	1.6	-0.8	-1.2	-2.5	1.3
Pack years of smoking	2.6	3.8	9.3	-1.8	0.9	2.5	-1.7	1.9	1.7	3.0	1.4
Impedance of whole body	0.2	1.2	2.7	-0.9	1.6	-0.1	-0.6	0.7	0.9	-1.4	-1.6
Leg fat mass (left)	1.1	4.3	8.7	1.7	-0.6	-2.2	2.1	-2.5	-1.6	-2.0	-3.0
Arm predicted mass (left)	0.5	2.3	4.8	1.2	-1.6	-2.0	1.0	-1.6	-2.2	-1.2	-1.0