TWAS hub - SHB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0720	0.0230	8.4e-06	0.031	0.040	0.031	0.040	0.037	1.1e-04	1.2e-05	1.1e-04	1.1e-05	2.5e-05
2	GTEx	Esophagus Mucosa	0.1240	0.0480	3.8e-03	0.004	NA	-0.003	NA	-0.003	1.7e-01	NA	6.8e-01	NA	5.5e-01
3	GTEx	Heart Left Ventricle	0.1721	0.0549	5.4e-04	0.024	NA	0.000	NA	0.003	1.9e-02	NA	3.1e-01	NA	2.1e-01
4	GTEx	Skin Sun Exposed Lower leg	0.0580	0.0270	5.6e-03	0.027	NA	0.018	NA	0.030	2.4e-03	NA	1.1e-02	NA	1.6e-03
5	GTEx	Testis	0.1520	0.0540	1.4e-03	0.044	NA	0.050	NA	0.074	5.1e-03	NA	2.9e-03	NA	3.6e-04
6	GTEx	Thyroid	0.0710	0.0280	2.5e-03	0.053	NA	0.039	NA	0.041	6.7e-05	NA	5.6e-04	NA	4.3e-04
7	METSIM	Adipose	0.0734	0.0223	1.2e-07	0.062	0.057	0.066	0.060	0.063	1.5e-09	5.2e-09	3.5e-10	2.5e-09	1.1e-09
8	ROSMAP	Brain Pre-frontal Cortex	0.0883	0.0234	3.3e-09	0.072	0.081	0.089	0.076	0.082	1.5e-09	1.2e-10	1.5e-11	4.5e-10	1.0e-10
9	TCGA	Pheochromocytoma and Paraganglioma	0.1000	0.0650	3.7e-03	0.059	0.039	0.003	NA	0.037	2.2e-03	1.1e-02	2.4e-01	NA	1.4e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Birth weight	5.9	12.8	22.0	-4.6	-1.7	-0.6	-3.8	-3.1	-4.7	-4.0	-4.3	-3.2
Bipolar Disorder (2011)	4.7	4.5	7.3	-2.5	-0.7	0.5	-2.5	-1.8	-2.6	-2.7	-2.2	-2.2
Eye problems/disorders: None of the above	4.5	5.2	10.7	2.7	1.5	-0.0	2.0	2.3	3.3	2.5	3.1	1.4
Happiness	3.9	4.7	8.4	-2.8	-1.1	-2.0	-2.1	-1.7	-2.8	-0.9	-2.9	-2.4
Chronotype (morning person)	3.8	8.8	19.5	-2.9	-1.2	-1.1	-3.7	-2.1	-4.4	-1.5	-3.6	-3.9
Hair/balding pattern: Pattern 4	3.8	9.1	22.4	-3.7	-2.6	-1.2	-4.7	-1.3	-2.8	-2.3	-2.3	-4.2
Lung FEV1/FVC ratio	3.7	18.7	35.9	-5.5	-1.4	-0.1	-3.4	-5.7	-6.0	-3.5	-5.9	-3.0
Length of working week for main job	3.7	4.1	12.6	1.8	1.1	1.0	2.2	0.7	2.5	3.6	1.8	2.0
Severe depression (siblings)	3.6	4.0	10.4	-2.0	-1.3	-0.2	-2.1	-2.6	-1.9	-0.2	-3.2	-2.4
Serious illness, injury or assault to yourself	3.6	4.4	7.7	2.4	-0.2	1.9	2.8	2.0	2.8	1.6	1.1	2.7
Mouth/teeth dental problems	3.5	5.4	11.6	2.1	0.6	1.4	2.2	1.9	3.4	3.3	2.7	1.8
Eye problems/disorders: Cataract	3.3	3.9	7.7	-1.8	-0.6	-0.8	-2.2	-1.8	-2.6	-2.8	-2.3	-1.7
Family relationship satisfaction	3.2	3.9	7.7	-2.1	-0.1	-1.5	-1.6	-2.5	-2.8	-1.7	-2.0	-2.2
Breastfed as a baby	3.0	3.7	7.5	-2.1	0.4	1.8	-2.3	-1.6	-2.7	-2.2	-1.6	-1.8
Schizophrenia (2018)	2.9	6.0	12.0	-3.5	-2.6	-0.9	-3.1	-1.8	-2.5	-1.3	-2.1	-3.0
Comparative body size at age 10	2.7	7.6	13.4	-3.6	-2.7	-2.4	-2.3	-2.4	-3.7	-1.2	-3.1	-2.6
Schizophrenia (2014)	2.6	5.8	11.1	-3.3	-2.7	-0.7	-3.1	-1.5	-2.4	-1.5	-2.2	-2.9
Friendships satisfaction	2.6	3.3	6.6	-2.2	-1.0	-0.1	-1.7	-1.8	-2.6	-1.6	-2.4	-1.7
Hand grip strength (right)	2.5	6.7	12.5	-3.5	-3.3	-0.4	-2.8	-2.5	-3.2	-1.4	-2.0	-2.5
Illness, injury, bereavement, stress in last 2 years	2.5	3.0	8.7	-2.3	-0.9	0.5	-1.8	-1.9	-3.0	-1.4	-1.1	-1.3
Maternal smoking around birth	2.3	3.3	9.8	1.4	-0.3	-0.9	0.7	3.1	2.4	1.1	2.8	1.4
Multivitamins +/- minerals	2.3	3.0	5.9	-1.8	-2.2	-0.4	-2.4	-1.2	-1.5	-1.9	-1.4	-1.9
Bipolar Disorder or Schizophrenia	2.2	5.3	11.3	-3.4	-1.8	-0.2	-2.9	-1.5	-2.3	-1.7	-2.8	-2.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.2	2.6	5.4	2.1	0.5	-1.2	2.1	0.7	1.6	1.3	2.3	1.7
Ever had hysterectomy (womb removed)	2.1	2.3	4.6	-2.1	-0.5	-0.2	-1.8	-1.0	-2.1	-2.0	-1.0	-1.5
Number of incorrect matches in round	2.1	3.4	6.4	2.2	2.5	1.2	2.3	0.4	2.0	1.8	1.4	1.8
Medication: Simvastatin	2.1	3.0	5.7	2.4	1.6	-1.3	2.0	0.3	1.8	1.2	1.8	2.3
High cholesterol (Self-reported)	2.1	3.8	7.5	2.6	1.7	-0.6	2.6	1.5	2.0	0.8	1.7	2.7
Heart disease (siblings)	2.1	2.6	4.7	1.9	1.3	-1.2	2.1	0.7	1.5	0.9	2.2	1.8
Mouth/teeth dental problems: Dentures	2.0	3.5	9.4	-1.6	0.0	-2.8	-1.4	-1.4	-3.1	-2.2	-0.8	-1.4
Average weekly beer plus cider intake	2.0	2.9	4.6	2.1	1.4	-2.1	1.8	1.0	1.8	1.4	1.5	1.8
Medication: Ventolin 100micrograms inhaler	1.8	2.3	6.3	1.6	1.1	0.2	0.7	2.4	1.6	1.2	2.5	0.5
Medication: Aspirin	1.8	2.3	4.9	1.9	1.7	1.2	2.1	0.5	1.3	0.8	1.0	2.2
High blood pressure (mother)	1.7	2.4	7.4	-0.6	0.2	0.1	-0.7	-2.7	-1.7	-1.6	-2.7	-0.8
Pain all over the body in last month	1.7	1.8	4.5	-1.5	-0.3	-0.6	-1.2	-1.6	-1.3	-0.5	-2.1	-1.7
Depression (Nagel 2018)	1.6	2.4	4.8	-1.3	0.6	-0.4	-1.0	-2.2	-2.1	-1.8	-2.2	-1.2
Diabetes (father)	1.6	2.0	4.4	-1.3	-1.9	-0.7	-2.1	-0.5	-1.6	-1.4	-0.3	-1.6
Medication: Cholesterol lowering	1.6	2.5	6.3	2.4	2.5	0.2	1.8	0.6	1.6	0.7	0.7	1.8
Had major operations	1.5	1.7	3.6	1.4	0.3	1.0	1.6	0.6	1.9	1.2	1.3	1.7
Father’s age at death	1.4	1.8	4.4	-1.8	-1.8	0.1	-1.9	0.0	-1.1	-0.2	-1.0	-2.1
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	9.7	-1.3	-3.1	0.1	-1.5	-0.4	-1.0	-0.8	-1.5	-1.4
Medication: Aspirin	1.4	1.8	4.4	1.7	1.4	0.9	2.0	0.3	1.2	0.6	0.8	2.1
Financial situation satisfaction	1.4	1.8	3.3	-1.0	-1.6	-0.6	-1.3	-1.2	-1.3	-1.0	-1.8	-1.7
Systolic blood pressure, automated reading	1.3	3.6	16.7	-1.3	1.4	-0.9	-0.7	-4.1	-1.9	-1.3	-2.2	-0.9
Taking other prescription medications	1.3	2.0	5.4	1.9	1.2	-0.4	1.1	2.3	1.5	0.0	1.6	1.0
Suffer from ‘nerves’	1.3	2.0	10.6	-0.5	1.0	0.1	0.6	-3.3	-0.7	-1.1	-1.9	0.4
Risk taking	1.3	1.8	9.7	0.0	0.5	2.0	-0.4	3.1	1.0	-0.1	0.8	-0.8
Systolic Blood Pressure	1.2	6.2	23.4	-1.2	2.5	-0.2	-0.9	-4.8	-2.0	-1.0	-3.8	-2.0
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.7	1.0	-0.2	-1.1	0.8	1.5	1.7	1.9	0.7	0.2
Birth weight of first child	1.2	2.2	6.1	-1.3	0.4	-0.6	-1.8	-2.5	-2.1	-0.5	-1.2	-1.6
Chronic bronchitis/emphysema (mother)	1.2	1.4	3.2	0.5	-0.7	-1.6	-1.8	1.5	-0.2	-0.7	0.7	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	6.4	-0.5	0.4	-0.8	-1.2	-0.7	-1.1	-2.5	-0.8	-1.0
Average weekly champagne plus white wine intake	1.2	1.7	3.2	-1.6	-1.8	-0.1	-1.5	-1.0	-1.3	-0.9	-1.5	-1.3
Intelligence (Savage-Jansen 2018)	1.1	3.4	5.4	1.3	1.2	2.3	2.0	1.6	2.3	1.7	1.8	2.2
Alzheimer’s Disease (in mother)	1.1	1.3	4.1	-0.6	1.6	2.0	0.0	-0.9	-0.8	0.3	-1.8	0.1
Hand grip strength (left)	1.1	3.0	9.2	-2.5	-3.0	-0.2	-2.0	-1.1	-1.7	-0.0	-0.6	-1.7
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	3.8	-1.1	-0.2	2.0	-0.9	-0.5	-0.7	-1.5	-0.9	-1.1
Illnesses of mother	1.1	1.3	3.8	0.3	-0.1	1.9	1.3	0.7	1.4	0.8	0.8	1.6
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.4	7.7	-2.7	-1.4	0.2	-1.4	-2.8	-2.1	-0.1	-2.5	-0.9
Reaction Time	1.0	1.9	4.1	-1.3	-0.1	-0.3	-1.1	-1.9	-1.7	-1.3	-2.0	-1.4
Blood Platelet Count	1.0	11.2	65.1	-0.7	-1.3	0.8	-3.1	0.5	-3.2	-8.1	-1.7	-3.2
Impedance of leg (right)	1.0	4.7	10.5	2.8	0.8	0.4	2.2	2.9	2.5	0.5	3.2	1.9
Diverticular disease/diverticulitis (self-reported)	1.0	1.1	5.3	-0.3	0.1	-1.7	0.3	-0.8	-0.7	-2.3	0.4	0.8
Impedance of leg (left)	1.0	4.8	9.3	3.0	1.1	0.6	2.3	2.6	2.6	0.8	3.1	1.9
Frequency of tiredness / lethargy in last 2 weeks	1.0	1.6	3.4	-1.1	-0.0	-0.5	-1.3	-1.4	-1.9	-1.6	-1.4	-1.1
Forced expiratory volume in 1-second (FEV1)	1.0	3.3	7.7	-2.5	-1.2	-0.2	-1.3	-2.8	-2.0	0.5	-2.6	-1.0
Medication: Lansoprazole	1.0	1.1	5.2	-0.3	0.9	-2.3	-0.5	0.2	-1.0	-1.4	-0.6	-0.9
Loud music exposure frequency	1.0	1.1	3.2	0.9	1.2	1.2	-0.1	1.8	1.1	-0.8	1.0	-0.1
Qualifications: College or University degree	1.0	3.1	5.3	0.9	0.7	2.3	1.5	1.3	2.2	2.0	1.9	2.3
Commuting to job workplace: Public transport	1.0	1.2	2.7	-1.6	-0.9	-0.3	-0.8	-1.3	-1.4	-1.1	-1.3	-0.6
Commuting to job workplace: Cycle	1.0	1.2	2.9	-0.7	-1.5	-1.3	-1.1	0.8	-0.8	-1.7	0.3	-1.1
Coronary Artery Disease (CAD)	0.9	1.1	3.5	0.6	1.2	-1.0	1.2	-0.9	0.7	1.9	0.0	1.0
Crohns Disease (2012)	0.9	1.5	4.2	0.6	1.1	2.1	-0.5	1.8	1.0	1.1	1.1	-0.7
Lupus	0.9	1.4	2.7	-1.4	-1.5	1.6	-1.3	-1.1	-0.8	-1.2	-0.5	-0.5
Frequency of depressed mood in last 2 weeks	0.9	1.2	3.4	-0.7	-0.2	-0.8	0.0	-1.8	-1.2	-1.3	-1.9	0.2
Hearing difficulty/problems with background noise	0.9	1.5	5.4	-1.2	0.1	-0.6	-1.2	-0.8	-1.8	-2.3	-0.5	-0.7
Qualifications: None of the above	0.9	1.9	5.4	1.5	0.6	-2.3	1.7	-0.1	1.0	-0.8	1.2	1.8
Shortness of breath walking on level ground	0.9	1.1	2.7	-1.6	-0.9	-0.8	-1.2	-1.2	-1.1	-0.4	-0.9	-0.9
Medication: Ibuprofen	0.9	1.0	3.5	-1.3	0.3	1.9	-0.9	-1.0	-0.3	0.0	-1.1	-0.7
Leg pain on walking	0.9	1.1	2.5	-0.8	1.4	0.6	-0.9	-1.1	-1.6	-0.7	-1.2	-0.8
Average weekly red wine intake	0.9	1.3	3.2	0.9	-1.4	-0.2	0.6	1.4	1.4	0.6	1.8	0.8
Mood swings	0.9	1.7	7.2	0.4	2.0	-2.7	0.9	-1.0	0.3	0.9	-0.3	0.9
Asthma (self-reported)	0.9	1.9	4.2	0.6	1.4	-2.0	-0.5	2.1	1.0	0.6	1.8	-1.2
Medication: Gliclazide	0.9	1.0	2.8	1.4	-0.1	-0.0	1.5	-0.8	1.0	0.0	0.8	1.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	1.9	5.8	-1.6	-0.6	-0.7	-1.3	-1.0	-2.4	-0.4	-1.9	-1.2
Age started oral contraceptive pill	0.9	1.1	2.8	-1.4	-0.9	-1.0	-1.5	0.1	-1.0	-0.2	0.1	-1.7
Basal cell carcinoma (self-reported)	0.9	1.1	2.8	-1.1	0.7	0.2	-0.6	-1.7	-0.9	0.9	-1.2	-1.3
Pack years of smoking	0.9	1.3	5.8	-1.2	-0.4	0.8	-0.5	-2.4	-0.5	0.2	-1.5	-0.7
HbA1C	0.8	0.8	2.6	0.0	-1.2	-1.6	0.6	-1.0	-0.0	-0.2	0.6	1.4
Relative age of first facial hair	0.8	1.7	4.4	1.3	2.1	0.7	1.6	0.3	1.2	1.3	1.2	1.3
Pack years adult smoking proportion	0.8	1.2	5.0	-1.2	-0.9	0.9	-0.3	-2.2	-0.3	0.5	-1.4	-0.4
Heart attack	0.8	1.1	7.0	0.3	0.9	2.6	-0.1	0.0	-0.5	-0.9	-0.8	-0.2
Noisy workplace	0.8	0.9	4.0	1.1	-0.6	-2.0	0.7	0.1	0.6	1.1	0.5	0.8
Asthma	0.8	1.5	3.8	0.3	0.9	-2.0	-0.7	1.8	0.6	0.7	1.6	-1.5
Depression (self-reported)	0.8	0.9	2.3	1.4	0.2	0.0	0.9	1.0	1.5	1.0	0.4	1.0
Prospective memory result	0.8	0.9	2.7	-0.6	-0.2	-0.2	-1.1	0.7	-1.7	-0.5	-0.8	-1.6
Blood clot in the leg (DVT)	0.8	1.1	3.1	0.1	0.1	1.7	-0.3	-1.8	-0.9	-1.0	-1.2	0.1
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	4.0	-1.8	-2.0	0.2	-1.3	-0.1	-1.0	-0.8	0.1	-1.0
Health satisfaction	0.8	1.0	1.9	-0.6	0.0	0.1	-1.2	-0.9	-1.3	-1.3	-1.2	-1.4
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.2	-1.5	-0.7	-0.9	-0.8	-0.9	-1.3	0.2	-1.0	-0.9
Medication: Seretide 50 evohaler	0.8	0.9	2.2	-1.2	-1.5	-1.1	-1.4	-0.1	-0.3	-0.3	-0.5	-0.9
Mean time to correctly identify matches	0.8	1.5	4.5	-0.6	0.6	-0.4	-1.0	-1.2	-1.4	-2.1	-1.3	-1.5
Knee pain experienced in last month	0.8	1.3	2.2	-1.2	0.7	0.1	-1.4	-1.5	-1.3	-1.2	-1.5	-0.8
Osteoporosis (self-reported)	0.8	1.0	5.3	0.4	2.3	0.3	0.6	-1.3	-0.9	-0.7	0.1	0.2
Wears glasses or contact lenses	0.8	0.9	2.8	-1.3	-0.4	-0.1	-1.3	-0.4	-1.0	-1.7	-0.5	-0.9
Medication: Bendroflumethiazide	0.8	1.1	4.2	-0.7	-0.1	0.1	-0.6	-1.7	-1.2	0.5	-2.1	-0.8
Number of operations (self-reported)	0.8	1.3	3.5	-1.4	-0.8	1.6	-0.5	-0.9	-0.5	-1.9	-1.1	0.3
Heart attack/myocardial infarction (self-reported)	0.8	1.1	6.7	0.2	0.9	2.6	-0.3	-0.1	-0.6	-0.8	-1.0	-0.4
Deep venous thrombosis (DVT) (self-reported)	0.8	1.1	4.1	0.4	0.3	2.0	-0.1	-1.6	-0.6	-0.9	-1.2	0.3
Prostate Cancer	0.7	1.0	3.0	-1.2	-1.7	0.5	-1.1	-0.1	-0.7	-0.3	-1.0	-1.0
Body Mass Index (BMI) (2010)	0.7	1.0	2.1	-1.4	-0.7	-1.4	-0.8	-0.7	-1.3	-0.1	-1.2	-0.5
Mean Putamen Volume	0.7	0.9	4.5	0.4	2.1	-0.0	0.3	-1.5	-0.4	0.1	-0.2	-0.7
Hearing difficulty/problems: Yes	0.7	1.1	2.7	-0.9	-0.7	-0.5	-1.6	0.1	-1.2	-1.4	0.0	-1.5
Medication for hormone replacement therapy	0.7	0.8	1.8	1.2	1.0	0.8	0.6	1.1	1.3	-0.1	0.8	0.1
High blood pressure	0.7	1.9	7.4	-0.1	2.7	0.1	-0.5	-1.7	-0.9	-1.3	-1.9	-0.6
Stomach or abdominal pain in last month	0.7	0.8	2.6	0.5	0.9	-0.6	-0.2	-1.0	-0.9	-1.6	-1.1	-0.4
Supplements: Glucosamine	0.7	0.9	2.2	-1.3	0.4	-0.0	-1.2	-0.7	-1.0	-0.4	-1.1	-1.5
Sitting height	0.7	5.0	9.4	-2.7	-1.6	2.5	-2.3	-1.5	-2.5	-1.0	-3.1	-2.0
Tense / ‘highly strung’	0.7	1.2	4.0	1.0	1.5	2.0	1.1	-0.6	1.0	0.4	-0.3	0.8
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.6	0.9	1.3	-0.3	1.3	-0.0	0.6	0.4	0.5	1.6
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	2.9	0.6	0.5	-1.2	1.3	1.7	0.9	1.3	1.3	0.9
Wheeze or whistling in the chest in last year	0.7	1.3	4.1	0.6	0.6	-2.0	-0.5	1.9	0.6	1.0	1.2	-0.6
Number of children fathered	0.7	0.8	2.0	-1.4	-0.3	-1.2	-0.9	-0.4	-0.7	-0.6	-0.9	-1.1
Neck or shoulder pain in last month	0.7	1.0	3.2	-0.4	1.5	0.2	0.2	-1.1	-0.6	-1.1	-1.8	-0.2
Heart disease (mother)	0.7	0.8	3.2	0.9	-0.2	-1.1	0.5	1.8	0.2	0.4	1.2	0.5
Smoking status: Previous	0.7	1.0	3.4	0.4	1.8	-1.2	1.2	-0.5	0.5	-0.3	-0.5	1.3
Leg fat-free mass (right)	0.7	3.6	8.0	-2.4	-1.4	0.1	-1.8	-2.6	-2.1	0.2	-2.8	-1.5
Leg predicted mass (right)	0.7	3.6	7.9	-2.4	-1.4	0.1	-1.8	-2.6	-2.1	0.2	-2.8	-1.5
Alcohol drinker status: Never	0.7	0.9	2.4	-1.1	0.2	-0.3	-0.7	-0.9	-1.4	-1.6	-0.4	-0.8
Ever had prostate specific antigen (PSA) test	0.7	0.8	3.7	-0.5	-0.1	-0.8	-0.3	-1.2	-0.6	-1.9	-0.5	-0.1
Pain experienced in last month	0.7	1.2	4.0	0.4	-2.0	0.5	0.1	1.7	0.3	1.0	1.6	0.1
Alcohol drinker status: Previous	0.7	0.8	2.2	0.4	-0.3	0.3	1.3	0.7	1.0	1.0	0.1	1.5
Impedance of whole body	0.7	3.7	7.6	2.6	1.4	0.6	2.2	1.5	2.3	0.3	2.7	2.0
Bipolar Disorder (2018)	0.6	0.9	2.8	-1.1	-0.9	0.9	-0.8	-0.2	-0.5	-1.2	-1.7	-0.5
Depressed Affect (Nagel 2018)	0.6	1.2	7.5	0.2	1.4	-2.7	-0.1	-0.9	-0.1	0.5	-0.3	-0.2
Crohns Disease (2017)	0.6	1.4	4.4	0.2	0.9	2.1	-1.2	1.7	-0.3	0.2	0.5	-1.6
HDL Cholesterol	0.6	0.9	2.5	0.8	-0.2	1.1	1.5	0.4	0.4	0.8	0.9	1.6
LDL Cholesterol	0.6	0.9	1.5	1.2	0.2	0.2	1.2	1.1	1.1	0.7	0.7	1.2
Neuroticism (2016)	0.6	0.8	2.6	-1.1	-0.3	-0.1	-1.2	-0.2	-0.9	-0.0	-1.6	-1.3
Tanning	0.6	6.9	13.5	-3.1	-0.5	-0.0	-3.2	-1.8	-3.7	-2.5	-2.4	-3.7
Vitamin and mineral supplements	0.6	0.9	1.8	0.8	1.2	0.0	1.3	0.8	0.7	1.4	0.4	0.9
Medication: Co-codamol	0.6	0.6	3.3	0.2	0.8	-0.5	0.6	-0.6	-0.4	-0.6	-1.8	0.5
Leg fat-free mass (left)	0.6	3.3	6.3	-2.4	-1.6	-0.2	-1.7	-2.3	-2.1	-0.0	-2.5	-1.3
Fed-up feelings	0.6	1.1	5.0	-0.8	0.3	-2.2	-1.1	-0.9	-0.5	0.1	-1.1	-1.1
Age when periods started (menarche)	0.6	1.4	3.1	1.7	1.5	0.0	1.1	0.8	1.1	-0.4	1.8	0.8
Leg predicted mass (left)	0.6	3.3	6.4	-2.4	-1.7	-0.2	-1.7	-2.3	-2.1	-0.0	-2.5	-1.3
Past tobacco smoking	0.6	1.1	3.0	-0.2	-1.3	1.7	-1.2	0.8	-0.6	0.7	0.2	-1.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.5	-0.8	0.4	-0.4	-0.9	-1.1	-1.0	-1.0	-1.6	-1.0
Financial difficulties in last 2 years	0.6	0.8	2.6	-0.6	-0.1	0.1	-0.9	-1.6	-0.7	-0.7	-1.5	-0.8
Impedance of arm (right)	0.6	2.9	6.0	2.2	1.4	-0.2	1.9	1.5	1.8	0.5	2.5	1.9
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	5.0	-0.4	0.7	2.2	-0.1	-0.2	0.4	0.4	-0.7	-0.1
Lung cancer (father)	0.6	0.7	2.3	0.7	0.6	-1.5	0.3	1.0	0.2	0.2	1.3	0.0
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.4	-0.9	-0.8	0.1	-0.5	-0.2	-0.8	-1.6	-1.2	-0.3
Exposure to tobacco smoke outside home	0.6	0.8	2.5	-1.2	-0.4	-0.8	-1.1	-0.7	-0.8	0.2	-0.5	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.6	-1.0	-0.3	0.1	-1.0	-1.3	-1.1	-1.1	-1.0	-0.7
Medication: Blood pressure	0.6	1.0	4.9	0.8	2.2	0.9	0.5	-0.8	0.5	0.6	-1.0	0.3
Supplements: Vitamin C	0.6	0.7	1.8	-0.4	0.0	1.0	-1.4	0.4	-0.5	-1.0	-0.5	-1.3
Back pain experienced in last month	0.6	0.8	1.8	-0.6	0.4	-1.4	-0.7	-0.8	-1.2	-0.8	-0.9	-0.9
Osteoarthritis (self-reported)	0.6	0.7	2.0	-1.4	-0.1	-0.4	-0.8	-0.5	-0.7	-0.7	-1.3	-0.9
Mother’s age at death	0.6	0.8	3.8	0.1	0.7	1.9	-0.6	-0.5	-0.6	-0.1	-0.8	-1.0
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.3	-0.4	-0.7	-0.8	-1.5	0.0	-0.9	-1.0	-0.1	-0.9
Pain type(s) experienced in last month: Hip pain	0.6	0.7	2.8	-0.6	0.1	-0.0	-1.1	-0.2	-0.8	0.2	-1.7	-1.1
Medication: Lisinopril	0.6	0.7	2.0	0.5	1.0	0.9	0.6	0.5	1.1	1.4	-0.8	0.6
Vascular/heart problems diagnosed by doctor	0.6	1.7	7.0	0.0	-2.6	-0.1	0.4	1.4	0.8	1.5	1.7	0.6
Irritable Bowel Disease (IBD)	0.5	1.2	4.5	0.1	0.5	2.1	-1.2	0.9	-0.9	-0.6	-0.2	-1.5
Ovarian Cancer	0.5	0.7	2.8	-0.5	-1.7	-1.4	-0.1	0.3	0.6	-0.3	0.7	0.1
Fasting Glucose	0.5	0.6	1.5	0.1	1.2	0.5	0.8	-0.7	-0.6	-0.7	0.6	0.9
BMI	0.5	2.7	9.1	-1.6	-0.6	-3.0	-0.2	-2.4	-1.9	0.0	-1.8	-0.2
Smoking Status	0.5	1.3	5.5	-1.3	-0.7	-2.4	-0.5	-0.9	-1.3	-0.5	-0.9	-0.5
Hypothyroidism (self reported)	0.5	1.0	5.9	0.0	-0.2	-0.5	0.4	2.4	0.6	1.4	1.0	0.2
Respiratory disease	0.5	1.1	2.9	0.6	0.9	-1.7	-0.6	1.7	0.9	-0.0	1.0	-1.1
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.8	-0.9	-0.0	1.1	-1.1	-0.1	-0.1	-1.0	-0.6	-1.3
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	3.4	-0.7	1.5	1.0	-1.1	-0.4	-0.4	-0.2	-1.5	-1.8
Qualifications: CSEs or equivalent	0.5	0.7	4.0	0.1	-0.9	-0.1	-0.0	-0.2	-0.1	1.0	-2.0	-0.6
Hayfever, allergic rhinitis or eczema	0.5	1.1	3.3	-0.7	-1.2	-0.7	-1.5	1.3	-0.0	-0.2	0.5	-1.8
Alcohol usually taken with meals	0.5	0.9	2.5	1.2	-1.3	1.6	0.4	0.8	0.4	0.7	0.9	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	3.1	-0.9	1.2	1.2	-1.1	-0.3	-0.4	-0.1	-1.5	-1.8
Illnesses of siblings	0.5	0.7	3.9	-0.2	-2.0	0.6	-0.6	-0.9	-0.4	0.5	-0.5	-0.1
Alcohol intake versus 10 years previously	0.5	0.8	2.8	0.8	1.7	0.8	0.7	-0.7	-0.7	-0.7	-0.8	0.4
Impedance of arm (left)	0.5	2.4	5.4	1.8	1.6	0.4	1.7	0.9	1.7	0.1	2.3	1.8
Headache pain in last month	0.5	0.8	2.4	0.6	1.6	0.8	0.9	-1.3	0.3	-0.3	-0.2	1.0
Overall health rating	0.5	1.1	2.5	0.4	1.4	-1.6	-0.3	-1.5	-0.7	-1.5	-0.6	-0.4
Hypertension (Self-reported)	0.5	1.4	6.2	0.0	2.5	0.1	-0.4	-1.5	-0.5	-0.9	-1.6	-0.4
Illnesses of father: Heart disease	0.5	0.7	2.6	0.1	-1.2	-0.5	0.3	-1.6	0.2	1.3	0.2	0.7
Illnesses of siblings: Diabetes	0.5	0.6	2.3	-0.4	-1.5	0.6	-0.9	0.3	-0.3	-0.8	-0.1	-1.1
Whole body fat-free mass	0.5	3.1	6.0	-2.5	-1.7	0.3	-1.8	-2.0	-1.9	0.4	-2.5	-1.4
Loneliness, isolation	0.5	0.7	2.0	-0.6	0.2	-1.1	-0.2	-1.1	-1.1	-0.1	-1.4	-0.3
Ever had bowel cancer screening	0.5	0.6	3.0	-0.3	0.9	0.6	-0.5	-0.2	-0.9	-1.7	0.2	-0.1
Whole body water mass	0.5	2.8	5.5	-2.3	-1.8	0.2	-1.7	-1.9	-1.7	0.5	-2.3	-1.3
Ever taken oral contraceptive pill	0.5	0.6	2.7	-0.3	-1.6	0.4	0.2	0.5	0.9	0.6	-0.6	0.7
Basal metabolic rate	0.5	2.6	5.3	-2.2	-1.7	-0.0	-1.4	-2.0	-1.7	0.3	-2.3	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.7	2.1	-0.2	0.5	0.8	-0.5	-0.7	-0.6	-1.5	-1.3	0.1
Schizophrenia vs Biploar Disorder	0.4	0.5	1.7	-1.1	0.2	-1.3	-0.5	-1.2	-0.0	0.2	0.1	-0.5
Alzheimer’s Disease (including proxy)	0.4	0.6	1.6	-0.5	1.2	1.3	0.2	-0.2	-0.1	0.2	-1.2	0.2
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.7	-0.4	-0.0	1.0	1.2	-1.0	0.9	0.9	-0.0	1.7
Rheumatoid Arthritis	0.4	0.5	1.6	-0.2	0.7	1.3	0.4	-0.6	-0.3	0.1	-1.1	0.5
Cardiovascular Disease	0.4	1.2	6.7	0.9	2.6	-0.1	0.3	-0.9	0.0	-1.0	-1.2	0.5
Type 2 Diabetes (T2D) (2018)	0.4	0.8	4.5	-0.3	-2.1	-0.3	0.3	-0.6	-0.3	0.1	-1.3	-0.0
Hair Pigment	0.4	11.8	25.8	-3.7	-4.0	0.8	-5.1	0.5	-2.6	-3.3	-3.9	-4.2
Average weekly spirits intake	0.4	0.5	2.1	-1.5	-0.4	-1.2	-0.3	0.2	0.1	0.1	0.3	-0.4
Supplements: Zinc	0.4	0.4	2.0	0.4	1.4	0.8	-0.4	-0.1	-0.1	-0.9	0.2	0.1
Average weekly fortified wine intake	0.4	0.4	2.0	-0.4	-0.4	-0.1	-0.5	-0.7	-0.7	-1.4	-0.1	-0.5
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.0	0.8	0.7	-0.6	1.0	-0.6	0.5	-0.2	0.1	0.8
Chronic bronchitis/emphysema (father)	0.4	0.5	1.1	-1.0	0.2	-0.1	-0.9	0.5	-0.4	-0.6	-0.5	-1.0
Forced vital capacity (FVC)	0.4	1.5	3.4	-1.6	-1.0	0.7	-0.9	-1.7	-1.1	1.1	-1.8	-0.7
Diabetes (self-reported)	0.4	0.6	3.5	0.1	-1.9	-0.6	0.8	0.4	0.1	-0.6	-0.5	0.6
Fluid intelligence score	0.4	0.8	2.5	-0.1	0.5	1.1	1.0	-0.8	1.1	0.7	0.2	1.6
Trunk fat-free mass	0.4	2.6	5.1	-2.2	-1.8	0.4	-1.6	-1.7	-1.6	0.6	-2.2	-1.2
Falls in the last year	0.4	0.5	1.6	1.3	0.9	-0.2	0.3	-0.1	0.6	-1.1	-0.4	0.1
Hair/balding pattern: Pattern 3	0.4	0.6	2.9	0.3	-0.2	-1.7	-0.5	0.6	0.5	0.7	0.7	-0.2
Number of live births	0.4	0.6	1.3	0.9	0.8	0.3	0.9	-1.1	0.0	0.1	-0.3	1.1
Pulse wave Arterial Stiffness index	0.4	0.4	1.4	-0.5	1.2	1.1	-0.6	-0.5	-0.0	-0.5	-0.3	-0.2
Trunk predicted mass	0.4	2.4	4.9	-2.2	-1.9	0.4	-1.5	-1.5	-1.5	0.6	-2.1	-1.2
Peak expiratory flow (PEF)	0.4	1.0	5.1	-0.8	0.1	-1.3	0.0	-2.3	-0.5	1.0	-0.9	0.1
Pulse wave reflection index	0.4	0.5	1.4	-0.5	1.2	0.4	0.1	-1.0	-0.4	-1.2	-0.3	0.3
Glaucoma (self-reported)	0.4	0.5	0.9	-0.9	0.1	0.9	0.1	-0.8	-1.0	-0.4	-0.9	0.6
High blood pressure (siblings)	0.4	0.6	3.8	-0.3	1.9	0.1	-0.3	0.9	-0.0	-0.1	0.1	-0.6
Forced vital capacity (FVC), Best measure	0.4	1.3	3.0	-1.7	-0.9	0.5	-0.8	-1.7	-1.2	0.7	-1.4	-0.4
Arm fat-free mass (right)	0.4	2.2	3.9	-2.0	-1.6	0.4	-1.5	-1.6	-1.5	0.3	-2.0	-1.3
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.3	0.1	-0.5	1.2	-0.8	0.4	-0.3	-1.2	-0.1	-0.7
Medication for pain relief, constipation, heartburn	0.4	0.7	2.0	-1.0	-0.7	-1.1	-0.9	-0.4	-1.0	-0.1	-0.3	-1.4
Migraine (self-reported)	0.4	0.5	1.3	0.1	-0.6	0.2	1.1	-0.1	0.8	0.9	0.6	1.0
Medication: Omeprazole	0.4	0.5	1.4	-0.3	0.4	1.1	-0.3	-0.6	-0.5	-1.2	-1.1	0.3
Arm predicted mass (right)	0.4	2.1	4.0	-1.9	-1.5	0.5	-1.4	-1.8	-1.5	0.2	-2.0	-1.2
Alcohol intake frequency.	0.4	1.0	3.7	-0.1	-0.1	1.1	0.3	-1.6	-1.1	0.3	-1.9	0.0
Comparative height size at age 10	0.4	2.0	3.9	-1.8	-1.3	1.6	-1.3	-0.4	-1.4	-0.1	-2.0	-1.5
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.9	-0.2	-1.4	0.4	-0.4	1.0	-0.0	-1.1	-0.3	-0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.8	0.2	0.5	-1.3	0.7	-1.3	0.4	-0.3	0.0	0.4
Medication: Atorvastatin	0.4	0.5	0.8	0.7	0.8	0.4	0.7	0.8	0.8	-0.7	-0.2	0.9
Illnesses of father: High blood pressure	0.4	0.5	1.2	0.7	0.7	1.1	0.3	-0.4	-0.4	-0.6	-1.1	0.2
Ever smoked	0.4	0.7	1.5	0.3	1.0	-1.0	1.2	-0.1	1.0	-0.2	0.5	1.0
Unable to work because of sickness or disability	0.4	0.5	1.8	0.5	-0.4	1.3	-0.1	1.0	0.2	-0.6	-0.8	0.1
Cholesterol lowering medication	0.4	0.5	3.0	0.3	-0.8	-1.7	0.3	0.2	0.0	-0.6	0.6	0.6
Arm predicted mass (left)	0.4	1.8	3.5	-1.8	-1.7	0.4	-1.2	-1.5	-1.4	0.4	-1.9	-1.0
Neuroticism (Nagel 2018)	0.3	0.7	2.6	-0.1	1.6	-1.0	-0.3	-1.4	-0.2	0.0	-0.7	-0.4
Worry (Nagel 2018)	0.3	0.6	2.4	0.1	1.6	1.0	0.1	-0.9	0.1	0.3	-0.7	-0.2
Blood Eosinophil Count	0.3	2.3	6.1	2.0	1.3	-0.2	1.3	2.0	1.5	-0.4	2.5	1.0
Lung FVC	0.3	1.4	3.5	-1.6	-0.2	0.5	-1.3	-1.0	-1.9	-0.6	-1.6	-1.0
Current tobacco smoking	0.3	0.5	1.4	-0.7	-1.2	-0.7	-0.6	-0.5	-0.7	0.7	0.1	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	1.6	-0.4	0.0	-0.9	-0.3	-0.8	-0.5	-0.7	-1.3	-0.3
Relative age voice broke	0.3	0.5	1.5	0.0	0.3	1.2	0.4	-0.8	0.2	0.4	0.9	0.8
Medication: Atenolol	0.3	0.4	1.2	0.1	-0.5	-0.5	0.4	-0.7	-0.7	-1.1	-0.5	0.5
Medication: Levothyroxine sodium	0.3	0.5	1.0	0.1	0.6	-1.0	1.0	0.9	0.1	0.1	0.7	1.0
Body mass index (BMI)	0.3	1.4	4.8	-1.4	-0.7	-2.2	-0.6	-1.3	-1.2	0.0	-1.1	-0.6
Hair/balding pattern: Pattern 2	0.3	0.3	0.9	-0.9	-0.2	0.8	-0.5	0.1	-0.5	-0.1	-0.7	-0.5
Had menopause	0.3	0.4	0.7	-0.8	-0.7	0.9	-0.7	0.3	-0.7	-0.5	0.1	-0.5
Had other major operations	0.3	0.3	1.1	-0.3	0.8	-0.4	0.1	1.0	-0.2	-0.5	0.7	0.3
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.5	0.3	-0.2	1.2	-0.8	0.6	-0.1	-0.6	0.1	-0.6
Allergy	0.3	0.8	2.4	-0.2	-0.4	1.0	0.8	-1.1	-0.1	-0.2	-1.2	1.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.2	-0.7	-1.1	0.2	-0.9	-0.0	-0.4	-0.3	-0.1	-1.0
Neuroticism score	0.3	0.7	2.8	0.4	1.7	-1.2	0.3	-0.7	0.5	0.8	-0.2	0.1
Weight	0.3	1.6	3.4	-1.8	-1.0	-0.9	-0.8	-1.8	-1.6	-0.0	-1.6	-0.6
Arm fat mass (right)	0.3	1.2	5.1	-1.2	-1.0	-2.3	-0.4	-1.3	-0.9	0.2	-0.7	-0.2
Exposure to tobacco smoke at home	0.3	0.3	0.8	0.7	-0.9	-0.9	0.3	0.1	0.5	0.5	0.3	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.4	-0.8	-0.1	0.3	-0.2	-1.0	-0.6	-0.2	-1.5	-0.1
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	1.4	-0.3	-1.2	-0.0	-0.6	-0.6	-0.8	-0.8	-0.3	-0.9
Medication: Amlodipine	0.3	0.4	1.7	-0.2	1.1	-0.2	-0.2	-1.3	-0.7	-0.3	-0.5	-0.5
Leg fat percentage (right)	0.3	1.0	7.8	-0.4	-0.4	-2.8	0.1	-0.4	-0.8	-0.1	0.2	0.1
Age at first live birth	0.3	0.6	2.6	0.4	1.5	1.6	0.1	0.1	0.0	0.4	0.6	-0.3
Pulse wave peak to peak time	0.3	0.4	1.7	0.3	-1.3	-1.1	0.4	0.5	-0.1	0.5	0.1	0.0
Emphysema/chronic bronchitis	0.3	0.3	1.2	0.2	0.4	0.2	0.2	-0.7	-0.5	-1.0	-1.1	0.0
Medication: Allopurinol	0.3	0.4	1.6	0.2	1.2	1.1	0.4	-0.1	0.0	-0.4	0.3	0.4
Leg fat mass (right)	0.3	1.0	4.6	-0.9	-0.5	-2.1	-0.3	-1.0	-1.2	0.1	-0.7	-0.3
Number of full sisters	0.3	0.3	0.9	0.2	0.6	-0.2	-0.4	1.0	0.6	0.7	0.5	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.1	-0.2	-1.1	-0.5	-0.0	-0.3	-1.0	-0.4	-0.9	-0.3
Long-standing illness, disability or infirmity	0.3	0.4	0.8	0.5	-0.2	-0.8	0.7	-0.7	-0.5	-0.9	-0.7	0.7
Diabetes diagnosed by doctor	0.3	0.4	2.3	0.2	-1.5	-0.5	0.6	0.0	-0.0	-0.5	-0.7	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	2.0	-0.3	0.6	-1.4	-0.4	0.4	-0.4	-0.1	0.0	-0.3
Mineral and other dietary supplements	0.3	0.3	1.0	0.1	0.5	-0.4	0.9	0.2	0.5	0.8	0.0	1.0
Illnesses of father: None of the above (group 1)	0.3	0.4	1.5	0.8	0.9	1.2	0.4	0.5	0.2	-0.1	-0.3	0.1
Smoking status: Current	0.3	0.4	1.1	-0.6	-1.1	-0.9	-0.3	-0.7	-0.8	0.6	-0.0	-0.3
Miserableness	0.3	0.5	2.0	0.8	1.4	-0.7	0.3	0.7	0.8	0.4	0.5	0.3
Arm fat-free mass (left)	0.3	1.5	3.2	-1.8	-1.8	0.2	-1.0	-1.3	-1.1	0.7	-1.6	-0.7
Irritability	0.3	0.5	1.5	-0.6	0.3	-1.1	-0.1	-1.2	-0.6	0.4	-0.9	-0.2
Fractured/broken bones in last 5 years	0.3	0.4	1.0	0.7	-0.2	-1.0	0.6	-0.4	0.5	-0.3	0.8	0.9
Diastolic blood pressure, automated reading	0.3	0.8	4.1	-0.6	1.1	-0.6	-0.5	-2.0	-0.4	-0.5	-0.8	-0.2
Myopia	0.3	0.5	2.7	-0.1	0.6	-0.3	-0.1	-1.6	-0.8	-0.4	-0.3	0.0
Leg fat mass (left)	0.3	1.0	4.2	-0.9	-0.5	-2.0	-0.3	-1.2	-1.3	0.2	-0.8	-0.3
Alzheimer’s Disease (in father)	0.2	0.2	0.9	-0.5	-0.3	0.3	0.2	0.5	0.9	0.6	0.4	0.3
Ulcerative Colitis (UC)	0.2	0.3	0.9	0.3	0.5	0.8	-0.4	0.1	-1.0	-0.5	-0.3	-0.5
Breast Cancer	0.2	0.4	1.2	-0.0	-0.7	0.9	-0.6	1.1	0.8	0.1	0.4	-0.3
Age at First Birth	0.2	0.3	0.8	-0.0	0.2	0.8	-0.2	-0.9	-0.4	-0.8	-0.5	-0.5
Triglycerides	0.2	0.3	1.5	0.4	0.2	-0.5	-0.4	0.2	-0.0	-1.2	0.5	-0.0
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.8	-0.4	-0.4	-0.9	-0.5	-0.4	-0.3	0.5	0.2	-0.5
Ulcerative Colitis	0.2	0.3	1.0	0.3	0.6	0.1	-0.4	-1.0	-0.8	-0.2	-0.7	-0.5
Heel T-Score	0.2	1.7	4.2	-2.0	1.1	-0.1	-1.5	0.1	-1.4	-0.5	-1.1	-2.1
Waist Hip Ratio (WHR)	0.2	0.8	2.0	0.9	0.8	0.4	1.1	-0.4	1.1	-0.7	0.8	1.4
Allergy or Eczema	0.2	0.5	1.4	-0.9	-0.5	0.0	-1.1	1.0	0.1	-0.2	-0.2	-1.2
Neuroticism	0.2	0.6	1.9	-0.4	0.8	-1.1	-0.3	-1.4	-0.7	0.4	-0.6	-0.5
Number of treatments/medications taken	0.2	0.4	1.5	0.3	-0.1	-1.2	0.0	0.4	0.1	-1.1	-0.0	0.4
Sensitivity / hurt feelings	0.2	0.4	1.3	-0.1	0.2	-1.2	0.4	-1.1	-0.4	-0.4	-0.6	0.4
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.9	0.4	0.7	-0.4	0.8	0.1	0.5	0.4	0.2	1.0
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.8	0.2	0.3	0.9	0.5	0.4	-0.5	-0.1	0.0	-0.1
Medication: Metformin	0.2	0.3	0.9	0.2	-1.0	-0.1	0.8	-0.3	-0.5	-0.3	0.3	0.7
Diabetes (mother)	0.2	0.2	1.3	0.2	0.4	-0.2	0.5	-1.1	-0.6	-0.0	-0.3	0.0
Townsend deprivation index at recruitment	0.2	0.3	1.1	-0.4	-1.0	0.4	-0.1	0.3	-0.7	-0.8	-0.3	0.0
Nervous feelings	0.2	0.4	2.2	0.3	-0.2	1.5	-0.2	-0.5	0.2	0.4	-0.6	-0.2
Arm fat percentage (right)	0.2	1.0	6.9	-0.6	-0.0	-2.6	0.2	-0.8	-0.7	0.2	0.0	0.4
Time employed in main current job	0.2	0.3	1.3	-0.3	0.6	-0.2	-0.5	0.4	0.0	-0.4	1.1	-0.5
Worrier / anxious feelings	0.2	0.3	1.3	0.0	1.1	0.5	-0.7	0.2	0.2	0.0	-0.3	-0.8
Qualifications: A levels/AS levels or equivalent	0.2	0.5	2.6	0.5	0.3	1.6	0.7	0.6	0.7	0.3	-0.0	0.7
Gout (self-reported)	0.2	0.3	1.1	0.5	-0.3	0.8	0.3	1.1	0.3	-0.7	0.5	0.2
Number of full brothers	0.2	0.2	0.5	-0.1	-0.5	-0.7	0.5	0.4	0.4	0.4	0.1	0.5
Angina (self-reported)	0.2	0.2	0.5	0.6	0.6	-0.4	0.1	-0.2	0.0	0.7	0.5	0.2
Whole body fat mass	0.2	0.8	1.9	-1.1	-0.3	-1.4	-0.4	-1.4	-1.0	-0.1	-0.7	-0.3
Pulse rate, automated reading	0.2	0.7	2.9	-0.4	-1.7	0.9	0.3	0.9	-0.2	0.2	0.3	1.0
Age at last live birth	0.2	0.3	1.1	0.2	1.0	0.9	0.3	0.1	0.3	-0.2	0.4	0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.3	0.7	0.8	0.5	0.7	-0.3	0.5	0.2	0.2	0.6	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	2.6	-0.1	-0.8	0.3	-0.1	-0.3	0.2	1.6	-0.0	-0.0
Arm fat percentage (left)	0.2	0.9	5.4	-0.8	0.1	-2.3	0.1	-1.2	-0.7	0.0	-0.2	0.2
Commuting to job workplace: Walk	0.2	0.2	0.8	-0.1	-0.6	-0.8	0.3	-0.0	0.1	0.9	-0.2	0.2
Medication for cholesterol	0.2	0.3	1.1	-0.2	-0.4	0.4	0.1	1.1	-0.3	0.8	0.2	0.0
Arm fat mass (left)	0.2	1.0	4.0	-1.2	-0.4	-2.0	-0.3	-1.3	-0.9	0.2	-0.6	-0.1
Number of self-reported non-cancer illnesses	0.2	0.4	1.5	0.3	1.2	0.7	0.0	-0.1	0.6	-1.0	-0.4	0.1
Guilty feelings	0.2	0.3	1.9	-0.1	-0.1	-0.8	-0.3	0.3	1.4	0.3	-0.0	-0.0
Eye problems/disorders: Glaucoma	0.2	0.2	0.5	-0.5	0.2	0.7	0.3	-0.4	-0.4	0.7	-0.4	0.4
Medication: Blood pressure	0.2	0.3	1.1	-0.1	0.9	-1.0	-0.3	-0.5	0.2	-0.5	-0.3	-0.1
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.8	-0.2	-0.4	0.9	-0.9	0.1	-0.3	-0.4	0.0	-0.7
Medication: Paracetamol	0.2	0.3	1.3	-0.3	-0.8	-0.3	-0.5	-0.3	-0.2	-0.1	-1.2	-0.1
Leg fat percentage (left)	0.2	0.9	6.5	-0.4	-0.2	-2.5	0.2	-0.8	-0.7	0.1	-0.0	0.1
Ever depressed for a whole week	0.2	0.2	0.5	0.6	0.5	0.5	-0.5	0.2	0.2	-0.7	-0.1	-0.5
Supplements: Calcium	0.2	0.3	1.3	0.0	-1.1	0.7	-0.1	-0.1	-0.5	-0.5	-0.0	-0.0
Major Depression (MDD)	0.1	0.2	0.9	-0.0	0.3	0.9	-0.2	0.1	0.5	0.2	0.5	0.0
Primary Biliary Cirrhosis	0.1	0.2	0.7	0.3	0.5	0.4	-0.5	-0.1	0.3	-0.9	0.2	-0.1
Blood Red Count	0.1	0.6	2.1	0.6	0.7	1.1	0.8	-1.5	-0.2	0.5	-0.2	0.8
Blood White Count	0.1	0.8	5.5	0.2	-0.6	-0.1	-0.2	-0.9	-0.6	-2.4	-0.4	-0.1
Height	0.1	1.2	4.6	-0.0	1.0	2.1	0.4	-2.0	-0.4	-0.7	-0.8	0.5
Angina	0.1	0.2	0.3	0.4	0.5	-0.5	0.2	-0.5	-0.1	0.5	0.3	0.4
Trunk fat percentage	0.1	0.5	1.8	-0.0	0.5	-1.4	0.7	-1.1	-0.1	0.0	0.3	0.8
Trunk fat mass	0.1	0.5	2.4	-0.7	0.1	-1.0	0.2	-1.6	-0.7	0.1	-0.5	0.3
Waist circumference	0.1	0.4	1.3	-0.3	0.3	-0.7	0.7	-1.1	-0.4	-0.4	-0.2	0.8
Medication: Ramipril	0.1	0.2	0.4	0.6	0.6	-0.1	-0.1	0.7	0.3	0.7	-0.2	-0.1
Hip circumference	0.1	0.5	1.5	-0.9	-0.3	-0.4	-0.1	-1.2	-1.1	0.3	-0.9	-0.0
Pulse rate	0.1	0.2	0.9	-0.4	-1.0	0.6	-0.5	-0.3	-0.4	-0.1	-0.4	-0.1
Standing height	0.1	1.0	5.2	-0.8	-0.8	2.3	-0.6	-1.0	-0.7	0.1	-0.8	-0.2
Medication: Paracetamol	0.1	0.1	0.8	0.2	-0.5	-0.0	-0.3	-0.1	0.3	-0.1	-0.9	-0.1
Body fat percentage	0.1	0.5	3.1	-0.3	0.3	-1.8	0.4	-1.0	-0.5	-0.1	0.1	0.4
Qualifications: nursing, teaching	0.1	0.2	1.0	-0.2	-0.0	1.0	-0.2	0.4	0.5	0.2	-0.1	-0.2
Breast cancer (self-reported)	0.1	0.2	0.5	-0.5	-0.3	0.6	0.3	0.5	-0.0	0.7	0.0	0.1
Hearing aid user	0.1	0.1	0.2	0.3	0.2	-0.1	0.0	-0.4	-0.4	0.5	0.2	-0.4
Worry too long after embarrassment	0.0	0.1	0.3	0.3	-0.1	0.5	0.2	-0.4	0.2	0.1	-0.2	0.0
Chest pain or discomfort	0.0	0.1	0.4	-0.1	0.6	-0.1	-0.3	0.3	0.1	0.2	-0.0	-0.3

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