TWAS hub - SKAP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	YFS	Blood	0.127	0.0256	0.0e+00	0.071	0.144	0.138	0.146	0.133	2.5e-22	1.2e-44	6.9e-43	2.1e-45	2.9e-41
2	TCGA	Thyroid Carcinoma	0.165	0.0600	7.4e-06	0.067	0.059	0.063	NA	0.066	4.5e-07	2.1e-06	8.7e-07	NA	4.8e-07

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Medication: Simvastatin	8.0	11.8	20.1	4.5	1.9
High cholesterol (Self-reported)	7.9	14.0	22.7	4.8	2.3
Hand grip strength (left)	6.3	16.5	26.5	5.1	2.5
Medication: Cholesterol lowering	6.2	9.6	18.4	4.3	0.9
Hand grip strength (right)	5.7	15.6	25.8	5.1	2.3
Ovarian Cancer	5.3	7.1	11.8	3.4	-1.5
Cardiovascular Disease	5.0	16.5	19.9	3.6	4.5
High blood pressure (mother)	4.8	6.7	7.1	2.5	2.7
Hair/balding pattern: Pattern 3	4.8	7.2	12.1	1.5	3.5
Forced expiratory volume in 1-second (FEV1), Best measure	4.8	15.4	16.5	3.8	4.1
Diastolic blood pressure, automated reading	4.4	13.7	13.7	3.7	3.7
Chronic bronchitis/emphysema (father)	4.1	4.8	9.6	-3.1	-0.3
Heart attack/myocardial infarction (self-reported)	3.9	5.1	7.9	1.5	2.8
Bilateral oophorectomy (both ovaries removed)	3.8	4.4	7.0	-2.6	1.3
Blood Red Count	3.7	35.4	70.6	8.4	-0.4
Had menopause	3.5	4.3	5.0	-1.9	-2.2
Asthma	3.5	6.9	11.6	3.4	-1.5
LDL Cholesterol	3.4	5.4	10.7	3.3	-0.2
Medication: Aspirin	3.4	4.5	5.5	1.9	2.3
Asthma (self-reported)	3.4	6.8	12.6	3.5	-1.0
Lung FVC	3.3	16.9	29.3	5.4	2.1
Hearing difficulty/problems: Yes	3.1	4.7	9.4	3.1	-0.0
Heart attack	3.1	4.0	6.0	1.4	2.4
Chronic bronchitis/emphysema (mother)	3.1	3.6	5.9	-2.4	1.2
Worry too long after embarrassment	3.1	5.2	6.9	2.6	1.9
Ever had bowel cancer screening	3.1	3.7	4.2	-2.0	-1.8
Forced expiratory volume in 1-second (FEV1)	3.0	10.2	10.6	3.2	3.1
Loud music exposure frequency	3.0	3.2	4.1	-1.6	-2.0
Forced vital capacity (FVC), Best measure	3.0	11.0	16.0	4.0	2.4
Ever used hormone-replacement therapy (HRT)	2.9	3.7	6.2	-2.5	-1.0
Illness, injury, bereavement, stress in last 2 years	2.9	3.5	7.0	0.0	-2.6
Cholesterol lowering medication	2.9	4.2	4.3	2.1	2.0
Birth weight of first child	2.8	5.0	7.5	-1.6	-2.7
Pulse rate, automated reading	2.8	9.0	10.4	3.2	2.8
Commuting to job workplace: Car/motor vehicle	2.8	3.2	4.9	1.2	2.2
Coronary Artery Disease (CAD)	2.7	3.2	3.9	1.6	2.0
Medication for cholesterol, blood pressure or diabetes	2.7	4.5	7.1	-2.7	-1.4
Average weekly spirits intake	2.6	3.2	3.6	1.9	1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.6	5.4	6.8	2.0	2.6
Crohns Disease (2017)	2.4	5.3	10.0	3.2	0.7
Mouth/teeth dental problems: Loose teeth	2.4	2.9	4.0	-2.0	1.3
Vascular/heart problems diagnosed by doctor	2.4	6.4	6.8	-2.5	-2.6
Respiratory disease	2.3	5.1	8.4	2.9	-1.3
Medication for hormone replacement therapy	2.3	2.5	2.8	-1.5	-1.7
Medication: Atenolol	2.3	2.9	3.9	1.4	2.0
Back pain experienced in last month	2.3	3.4	6.6	-0.4	2.6
Financial difficulties in last 2 years	2.2	3.0	5.8	-0.3	2.4
Happiness	2.2	2.6	5.1	2.3	-0.3
Peak expiratory flow (PEF)	2.2	5.1	5.6	-2.1	2.4
Migraine (self-reported)	2.2	2.8	3.1	1.8	1.6
Number of self-reported non-cancer illnesses	2.2	3.9	7.1	2.7	0.8
Pain experienced in last month	2.2	3.7	7.3	0.2	-2.7
Alcohol drinker status: Previous	2.2	2.5	4.4	-2.1	0.8
Irritable Bowel Disease (IBD)	2.1	5.0	9.9	3.1	0.3
Primary Biliary Cirrhosis	2.1	2.9	5.8	2.4	-0.3
Lung FEV1/FVC ratio	2.1	10.7	17.3	-2.0	4.2
Diverticular disease/diverticulitis (self-reported)	2.1	2.5	4.9	-0.2	2.2
Frequency of tenseness / restlessness in last 2 weeks	2.1	3.3	5.1	1.3	2.2
Tense / ‘highly strung’	2.1	3.5	3.8	2.0	1.8
Hypertension (Self-reported)	2.1	5.8	6.6	2.6	2.3
Blood White Count	2.0	14.8	29.1	-5.4	0.7
Hearing difficulty/problems with background noise	2.0	3.2	6.4	2.5	0.1
Crohns Disease (2012)	1.9	3.0	6.0	2.4	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.9	2.3	2.3	1.5	1.5
Lupus	1.8	2.8	2.9	1.6	-1.7
Number of treatments/medications taken	1.8	3.2	4.7	2.2	1.3
Maternal smoking around birth	1.8	2.6	4.9	-2.2	-0.4
Qualifications: CSEs or equivalent	1.8	2.3	4.7	-0.1	2.2
High blood pressure	1.8	5.1	5.6	2.4	2.2
Forced vital capacity (FVC)	1.8	6.9	10.6	3.2	1.8
Blood clot in the leg (DVT)	1.8	2.3	3.8	0.9	2.0
Shortness of breath walking on level ground	1.8	2.2	4.3	0.1	2.1
Heart disease (mother)	1.8	2.1	2.5	1.3	1.6
Allergy	1.7	3.9	7.6	-2.8	-0.4
Number of live births	1.7	2.4	2.5	-1.5	-1.6
Medication: Aspirin	1.7	2.3	3.5	1.1	1.9
Medication: Atorvastatin	1.7	2.1	2.6	1.6	1.3
Ulcerative Colitis (UC)	1.6	3.0	6.0	2.4	-0.1
Eye problems/disorders: None of the above	1.6	1.9	3.5	-1.9	-0.5
Number of operations (self-reported)	1.6	2.4	4.0	-0.9	-2.0
Smoking Status	1.5	3.6	6.8	-2.6	0.5
Chronotype (morning person)	1.5	3.4	4.4	1.6	2.1
Nervous feelings	1.5	2.8	3.7	1.9	1.4
Medication: Lansoprazole	1.5	1.7	3.0	-0.6	1.7
Had major operations	1.5	1.8	2.9	1.7	-0.8
Smoking status: Current	1.5	2.3	4.6	-2.1	-0.3
Tinnitus: Yes, now most or all of the time	1.5	1.8	3.5	1.9	-0.1
Ever had prostate specific antigen (PSA) test	1.5	1.8	1.9	-1.4	-1.3
Prostate Cancer	1.4	2.0	2.6	-1.6	-1.2
Diabetes (mother)	1.4	1.8	2.9	-1.7	-0.9
Severe depression (siblings)	1.4	1.6	2.2	-1.5	1.0
Medication: Ramipril	1.4	1.8	3.5	1.9	0.3
Father’s age at death	1.4	1.9	3.5	-1.9	0.5
Pulse rate	1.4	2.4	2.7	1.5	1.6
Glaucoma (self-reported)	1.4	1.7	2.7	1.6	0.8
Health satisfaction	1.4	1.8	3.0	1.7	0.7
Eye problems/disorders: Cataract	1.4	1.6	2.9	1.7	0.5
Commuting to job workplace: Public transport	1.4	1.7	3.2	-0.3	-1.8
Illnesses of father: High blood pressure	1.4	1.7	3.2	0.3	1.8
Bipolar Disorder (2011)	1.3	1.2	2.0	1.4	0.7
Hypothyroidism (self reported)	1.3	2.9	3.0	1.7	1.7
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.1	4.2	-0.1	2.1
Illnesses of mother	1.3	1.6	3.1	0.3	-1.8
Medication: Amlodipine	1.3	1.8	3.3	0.6	1.8
Qualifications: nursing, teaching	1.3	2.0	4.0	-0.1	2.0
Angina	1.2	1.6	2.8	0.5	1.7
Frequency of unenthusiasm / disinterest in last 2 weeks	1.2	1.7	3.3	0.2	1.8
Past tobacco smoking	1.2	2.3	4.4	2.1	0.4
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	1.8	-1.4	-1.0
Medication: Blood pressure	1.2	2.2	3.5	0.9	1.9
Friendships satisfaction	1.2	1.4	2.8	1.7	0.3
Hair Pigment	1.1	30.5	59.6	-7.7	1.2
Townsend deprivation index at recruitment	1.1	1.6	1.9	-1.1	-1.4
Medication: Levothyroxine sodium	1.1	1.9	3.7	1.9	0.4
Ever highly irritable/argumentative for 2 days	1.1	1.3	1.9	-0.9	-1.4
Age at last live birth	1.1	1.6	3.1	1.8	0.3
Leg pain on walking	1.1	1.4	1.6	-1.3	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.3	-1.5	0.6
Medication: Bendroflumethiazide	1.1	1.6	1.7	1.3	1.3
Bipolar Disorder (2018)	1.0	1.5	2.9	1.7	0.3
Type 2 Diabetes (T2D) (2018)	1.0	2.0	3.8	-2.0	-0.3
Medication: Metformin	1.0	1.4	2.7	-1.6	-0.5
Serious illness, injury or assault to yourself	1.0	1.2	2.1	0.6	1.4
Supplements: Glucosamine	1.0	1.3	2.1	-0.7	-1.4
Number of full brothers	1.0	1.2	1.7	1.3	0.9
Medication for pain relief, constipation, heartburn	1.0	1.8	2.5	-1.0	-1.6
Neck or shoulder pain in last month	1.0	1.4	1.8	-1.0	1.3
Medication: Omeprazole	1.0	1.2	1.6	-1.3	-0.9
Illnesses of siblings: Diabetes	1.0	1.3	1.9	-0.8	-1.4
Commuting to job workplace: Walk	1.0	1.1	1.3	1.1	1.0
Wears glasses or contact lenses	1.0	1.1	2.1	0.4	-1.4
Financial situation satisfaction	1.0	1.3	1.3	1.1	1.1
Risk taking	1.0	1.5	1.8	-1.3	-1.1
Deep venous thrombosis (DVT) (self-reported)	1.0	1.2	2.2	0.5	1.5
Breast Cancer	0.9	2.1	4.2	-0.3	-2.0
Leg fat percentage (right)	0.9	3.3	6.2	-2.5	-0.6
Exposure to tobacco smoke outside home	0.9	1.2	1.3	1.1	-1.1
Comparative body size at age 10	0.9	2.4	3.3	-1.8	-1.2
Angina (self-reported)	0.9	1.2	2.2	0.4	1.5
Medication: Seretide 50 evohaler	0.9	1.0	1.8	-0.4	-1.3
Family relationship satisfaction	0.9	1.1	2.3	1.5	0.1
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	2.4	-1.6	0.5
Breast cancer (self-reported)	0.9	1.1	2.2	0.2	1.5
Illnesses of father: None of the above (group 1)	0.9	1.1	1.4	0.9	-1.2
Average weekly champagne plus white wine intake	0.9	1.2	1.9	-1.4	-0.8
Eye problems/disorders: Glaucoma	0.9	1.1	2.2	1.5	-0.2
Pain type(s) experienced in last month: Hip pain	0.9	1.1	1.5	0.8	1.2
Alcohol drinker status: Never	0.9	1.1	2.0	-0.3	1.4
Ever depressed for a whole week	0.9	1.1	1.5	1.2	-0.9
Worry (Nagel 2018)	0.8	1.7	2.4	1.5	1.1
Fasting Glucose	0.8	1.0	1.5	-0.7	-1.2
Trunk fat percentage	0.8	3.4	3.8	-1.9	-1.7
Current tobacco smoking	0.8	1.4	2.7	-1.6	0.1
Depression (self-reported)	0.8	1.0	1.8	-0.2	1.4
Medication: Ventolin 100micrograms inhaler	0.8	1.0	1.4	0.8	-1.2
Body fat percentage	0.8	3.0	4.4	-2.1	-1.3
Number of children fathered	0.8	0.9	0.9	0.9	0.9
Suffer from ‘nerves’	0.8	1.3	2.5	-1.6	0.4
Ever smoked	0.8	1.4	2.5	-1.6	-0.4
Leg fat percentage (left)	0.8	3.1	6.0	-2.4	-0.4
Schizophrenia vs Biploar Disorder	0.7	0.9	1.6	-0.4	-1.2
Reaction Time	0.7	1.3	2.6	1.6	-0.1
Body Mass Index (BMI) (2010)	0.7	1.0	2.0	-0.1	-1.4
Systolic Blood Pressure	0.7	3.7	7.1	0.6	2.7
Age when periods started (menarche)	0.7	1.8	2.2	1.5	1.2
Trunk fat mass	0.7	2.9	4.2	-2.0	-1.3
Pain all over the body in last month	0.7	0.7	0.8	0.9	0.8
Mouth/teeth dental problems: Dentures	0.7	1.2	2.3	1.5	0.3
Lung cancer (father)	0.7	0.8	1.2	-1.1	-0.6
Mouth/teeth dental problems: Bleeding gums	0.7	1.0	1.2	-0.8	1.1
Wheeze or whistling in the chest in last year	0.7	1.3	2.5	1.6	0.4
Hearing aid user	0.7	0.8	1.5	1.2	0.4
Medication: Lisinopril	0.7	0.9	1.7	-0.4	1.3
Unable to work because of sickness or disability	0.7	0.8	1.6	0.3	1.3
Supplements: Calcium	0.7	0.8	1.4	1.2	0.5
Depression (Nagel 2018)	0.6	0.9	1.6	-0.3	1.3
Alzheimer’s Disease (in father)	0.6	0.6	1.3	0.1	-1.1
Heel T-Score	0.6	4.4	8.8	-3.0	-0.3
Relative age of first facial hair	0.6	1.2	1.5	-1.2	-0.9
Ever had hysterectomy (womb removed)	0.6	0.7	1.3	-1.1	0.3
Taking other prescription medications	0.6	0.9	1.0	1.0	0.9
Arm fat percentage (right)	0.6	2.2	2.6	-1.3	-1.6
Falls in the last year	0.6	0.8	1.1	-1.1	0.7
Breastfed as a baby	0.6	0.7	1.4	-1.2	-0.2
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	1.3	1.1	1.0
Mean time to correctly identify matches	0.6	1.2	2.5	1.6	0.0
Whole body fat mass	0.6	2.5	3.7	-1.9	-1.1
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	1.1	0.5	1.0
Smoking status: Previous	0.6	0.9	1.7	-1.3	0.2
Mother’s age at death	0.6	0.7	0.8	-0.8	-0.9
Supplements: Fish oil (including cod liver oil)	0.6	0.8	0.8	0.9	-0.8
Commuting to job workplace: Cycle	0.6	0.7	1.0	-1.0	0.7
Alzheimer’s Disease (including proxy)	0.5	0.7	1.2	-0.5	-1.1
Major Depression (MDD)	0.5	0.6	0.8	-0.9	-0.7
HbA1C	0.5	0.6	1.2	0.1	1.1
Ulcerative Colitis	0.5	0.8	1.2	0.6	-1.1
Vitamin and mineral supplements	0.5	0.6	0.7	-0.7	0.8
Medication: Co-codamol	0.5	0.6	1.1	-0.5	-1.0
Stomach or abdominal pain in last month	0.5	0.7	1.0	-1.0	0.6
Neuroticism score	0.5	1.0	1.7	1.3	0.6
Prospective memory result	0.5	0.6	0.9	-0.5	-1.0
Age at first live birth	0.5	0.9	1.7	1.3	-0.2
Leg fat mass (right)	0.5	1.8	3.4	-1.8	-0.4
Alcohol intake frequency.	0.5	1.2	2.3	-1.5	-0.3
Number of full sisters	0.5	0.6	1.2	0.0	1.1
Overall health rating	0.5	1.1	1.6	1.3	0.8
Chest pain or discomfort	0.5	0.7	0.8	0.9	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	1.2	1.1	1.0
Arm fat percentage (left)	0.5	1.8	2.2	-1.2	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	0.7	-0.8	0.6
Mineral and other dietary supplements	0.5	0.7	1.2	-1.1	0.5
Medication: Paracetamol	0.5	0.8	1.6	1.3	0.1
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	0.9	-1.0	-0.4
Leg fat mass (left)	0.5	1.9	3.6	-1.9	-0.4
Alzheimer’s Disease (in mother)	0.4	0.4	0.8	-0.9	-0.2
Schizophrenia (2014)	0.4	0.8	1.4	-0.4	-1.2
Type 2 Diabetes (T2D) (2012)	0.4	0.4	0.7	-0.5	-0.8
Blood Eosinophil Count	0.4	3.0	5.8	-2.4	0.6
Waist Hip Ratio (WHR)	0.4	1.8	3.5	0.2	-1.9
Frequency of depressed mood in last 2 weeks	0.4	0.6	0.8	0.6	0.9
Diabetes (father)	0.4	0.6	0.9	0.5	0.9
Impedance of leg (right)	0.4	1.8	3.6	-1.9	0.1
Hayfever, allergic rhinitis or eczema	0.4	0.8	1.6	1.2	-0.2
Multivitamins +/- minerals	0.4	0.6	1.1	0.2	-1.1
Impedance of leg (left)	0.4	1.8	3.5	-1.9	0.2
Alcohol usually taken with meals	0.4	0.6	0.8	0.6	0.9
Worrier / anxious feelings	0.4	0.8	1.4	1.2	0.3
Noisy workplace	0.4	0.5	0.9	0.3	1.0
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	0.6	-0.5	0.8
Arm fat mass (right)	0.4	1.7	1.9	-1.4	-1.2
Hair/balding pattern: Pattern 4	0.4	0.9	1.0	-1.0	-0.9
Supplements: Vitamin C	0.4	0.4	0.9	0.9	-0.0
Knee pain experienced in last month	0.4	0.7	1.1	-0.4	-1.1
Illnesses of father: Heart disease	0.4	0.6	1.1	1.0	-0.3
Medication for cholesterol	0.4	0.6	0.9	-1.0	-0.5
Arm fat mass (left)	0.4	1.6	1.6	-1.3	-1.3
Guilty feelings	0.4	0.6	1.0	1.0	0.5
Medication: Blood pressure	0.4	0.7	1.3	1.1	-0.3
Fractured/broken bones in last 5 years	0.4	0.5	0.6	-0.7	0.8
Myopia	0.4	0.6	0.6	-0.7	-0.8
Bipolar Disorder or Schizophrenia	0.3	0.7	1.1	1.0	-0.5
Neuroticism (Nagel 2018)	0.3	0.8	0.8	0.9	0.9
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	0.7	-0.8	0.3
Systolic blood pressure, automated reading	0.3	0.8	1.6	-0.1	1.3
Supplements: Zinc	0.3	0.4	0.6	-0.8	-0.3
Average weekly fortified wine intake	0.3	0.3	0.7	0.8	0.2
Had other major operations	0.3	0.4	0.4	-0.7	-0.6
Illnesses of siblings	0.3	0.4	0.7	-0.9	0.1
Impedance of arm (right)	0.3	1.2	1.7	-0.8	-1.3
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	0.7	0.1	0.8
Medication: Paracetamol	0.3	0.5	0.5	0.7	0.7
Medication: Allopurinol	0.3	0.4	0.5	-0.5	-0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	0.6	-0.3	0.8
Average weekly red wine intake	0.3	0.5	0.8	-0.4	-0.9
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.7	0.3	-0.8
Osteoporosis (self-reported)	0.3	0.3	0.6	0.8	-0.2
Average weekly beer plus cider intake	0.3	0.5	0.9	-0.9	-0.4
Basal cell carcinoma (self-reported)	0.3	0.3	0.4	0.5	0.6
Heart disease (siblings)	0.3	0.4	0.4	0.6	0.7
Schizophrenia (2018)	0.2	0.4	0.7	-0.1	-0.9
Mean Putamen Volume	0.2	0.2	0.3	-0.3	-0.6
Allergy or Eczema	0.2	0.5	0.6	0.6	0.8
Neuroticism	0.2	0.6	0.9	1.0	0.5
Sensitivity / hurt feelings	0.2	0.3	0.3	0.5	0.5
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.5	0.7	0.0
Waist circumference	0.2	0.8	1.0	-1.0	-0.8
Hair/balding pattern: Pattern 2	0.2	0.2	0.4	-0.6	-0.1
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.3	-0.6	-0.4
Mouth/teeth dental problems	0.2	0.3	0.4	0.5	-0.6
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.4	0.6	-0.2
Weight	0.2	0.9	1.7	-1.3	-0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.4	0.9	0.1	0.9
Impedance of arm (left)	0.2	0.9	1.6	-0.4	-1.3
Exposure to tobacco smoke at home	0.2	0.2	0.4	-0.2	-0.7
Pulse wave reflection index	0.2	0.3	0.3	-0.6	0.5
Gout (self-reported)	0.2	0.2	0.4	-0.7	0.1
Birth weight	0.2	0.4	0.8	-0.2	-0.9
High blood pressure (siblings)	0.2	0.3	0.6	0.8	0.1
Qualifications: College or University degree	0.2	0.5	0.8	0.4	0.9
Emphysema/chronic bronchitis	0.2	0.2	0.5	-0.7	0.1
Comparative height size at age 10	0.2	0.8	1.7	0.1	-1.3
Mood swings	0.2	0.4	0.6	0.4	-0.7
Loneliness, isolation	0.2	0.3	0.4	-0.6	0.6
Long-standing illness, disability or infirmity	0.2	0.3	0.5	-0.7	-0.1
Diabetes diagnosed by doctor	0.2	0.4	0.8	-0.9	0.1
Ever taken oral contraceptive pill	0.2	0.2	0.3	-0.6	-0.2
Irritability	0.2	0.4	0.8	0.9	0.1
Depressed Affect (Nagel 2018)	0.1	0.2	0.4	-0.7	0.0
HDL Cholesterol	0.1	0.1	0.2	0.4	-0.3
Blood Platelet Count	0.1	0.9	1.3	-1.1	0.8
BMI	0.1	0.8	1.5	-1.2	-0.4
Height	0.1	2.2	4.2	-2.1	0.5
Pack years adult smoking proportion	0.1	0.2	0.3	0.4	0.6
Relative age voice broke	0.1	0.2	0.3	0.3	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.1	0.2	0.3	0.4
Sitting height	0.1	0.5	0.8	-0.4	0.9
Body mass index (BMI)	0.1	0.6	0.6	-0.8	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.5	0.2	0.7
Qualifications: None of the above	0.1	0.2	0.2	-0.5	-0.4
Diabetes (self-reported)	0.1	0.2	0.4	-0.6	-0.2
Fluid intelligence score	0.1	0.2	0.5	-0.0	-0.7
Trunk fat-free mass	0.1	0.6	0.8	-0.6	0.9
Hip circumference	0.1	0.4	0.8	-0.9	0.3
Time employed in main current job	0.1	0.1	0.1	-0.4	0.0
Alcohol intake versus 10 years previously	0.1	0.1	0.2	0.4	0.2
Pulse wave Arterial Stiffness index	0.1	0.2	0.2	-0.3	0.5
Trunk predicted mass	0.1	0.6	0.9	-0.6	1.0
Standing height	0.1	1.4	1.5	-1.2	1.2
Length of working week for main job	0.1	0.1	0.2	-0.4	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.1	0.1	-0.3	-0.3
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	0.4	0.6	0.2
Headache pain in last month	0.1	0.1	0.3	0.5	-0.0
Arm fat-free mass (right)	0.1	0.6	1.1	-0.4	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.2	0.3	-0.5	0.2
Pulse wave peak to peak time	0.1	0.1	0.2	0.2	-0.4
Medication: Ibuprofen	0.1	0.1	0.2	0.5	0.1
Arm predicted mass (right)	0.1	0.4	0.7	-0.3	0.8
Osteoarthritis (self-reported)	0.1	0.1	0.3	-0.0	-0.5
Medication: Gliclazide	0.1	0.1	0.1	0.2	-0.3
Whole body water mass	0.1	0.5	1.1	-0.1	1.0
Miserableness	0.1	0.1	0.1	-0.3	0.4
Arm fat-free mass (left)	0.1	0.6	0.7	-0.6	0.8
Age started oral contraceptive pill	0.1	0.2	0.4	0.0	-0.6
Impedance of whole body	0.1	0.7	0.8	-0.9	-0.8
Arm predicted mass (left)	0.1	0.5	0.6	-0.8	0.7
Intelligence (Savage-Jansen 2018)	0.0	0.0	0.1	0.2	-0.2
Verbal and Numeric Reasoning (VNR)	0.0	0.0	0.1	-0.2	-0.1
Age at First Birth	0.0	0.0	0.1	-0.3	-0.1
Neuroticism (2016)	0.0	0.1	0.1	-0.2	0.3
Rheumatoid Arthritis	0.0	0.1	0.1	-0.3	-0.1
Triglycerides	0.0	0.1	0.1	-0.3	0.0
Tanning	0.0	0.6	1.1	1.0	0.3
Leg fat-free mass (left)	0.0	0.1	0.2	0.1	0.4
Fed-up feelings	0.0	0.1	0.2	0.1	-0.4
Tinnitus: Yes, but not now, but have in the past	0.0	0.0	0.0	0.1	0.2
Leg predicted mass (left)	0.0	0.1	0.2	0.2	0.5
Number of incorrect matches in round	0.0	0.0	0.0	0.1	-0.1
Whole body fat-free mass	0.0	0.3	0.5	-0.2	0.7
Leg fat-free mass (right)	0.0	0.3	0.3	0.5	0.5
Leg predicted mass (right)	0.0	0.2	0.3	0.5	0.4
Basal metabolic rate	0.0	0.3	0.3	-0.5	0.5
Pack years of smoking	0.0	0.0	0.0	0.1	0.1

Hub : Genes

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Trait associations