Hub : Genes

SLC16A4

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1170	0.0400	4.9e-04	0.074	NA	0.078	NA	0.084	1.1e-06	NA	6.5e-07	NA	2.4e-07
2	GTEx	Adrenal Gland	0.2002	0.0748	3.5e-03	0.073	NA	0.137	NA	0.140	1.3e-03	NA	1.2e-05	NA	1.0e-05
3	GTEx	Cells Transformed fibroblasts	0.0850	0.0330	2.6e-03	0.078	NA	0.047	NA	0.074	1.7e-06	NA	2.0e-04	NA	3.3e-06
4	GTEx	Heart Atrial Appendage	0.1590	0.0650	8.8e-03	0.015	NA	0.024	NA	0.021	6.5e-02	NA	3.0e-02	NA	3.8e-02
5	GTEx	Testis	0.3570	0.0680	2.3e-08	0.318	NA	0.265	NA	0.293	1.1e-14	NA	3.6e-12	NA	1.8e-13
6	TCGA	Bladder Urothelial Carcinoma	0.2030	0.0830	3.5e-06	0.056	0.080	0.079	NA	0.052	1.6e-05	2.6e-07	3.2e-07	NA	2.9e-05
7	TCGA	Lung Adenocarcinoma	0.0306	0.0217	4.7e-03	0.016	0.015	0.020	NA	0.015	5.0e-03	6.0e-03	1.7e-03	NA	5.9e-03
8	TCGA	Prostate Adenocarcinoma	0.0478	0.0225	3.2e-06	0.066	0.058	0.048	NA	0.052	1.9e-07	9.5e-07	8.9e-06	NA	3.5e-06
9	TCGA	Uterine Corpus Endometrial Carcinoma	0.2440	0.1360	6.5e-04	0.100	0.077	0.026	NA	0.059	9.9e-04	3.7e-03	6.3e-02	NA	9.7e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.2	0.4	1.6	-0.3	-1.3	-0.1	0.8	0.1	-1.0	-0.3	0.0	-0.3
Bipolar Disorder or Schizophrenia	0.8	2.1	7.7	-1.5	-2.0	-1.1	-0.4	-1.0	-2.8	-0.4	-1.4	0.4
Depressed Affect (Nagel 2018)	0.5	1.1	2.4	-0.6	0.6	-1.6	-0.0	-1.5	-0.3	-0.9	-1.3	-1.5
Depression (Nagel 2018)	0.6	1.0	2.6	-0.5	0.7	-1.4	-0.5	-1.6	-0.3	-0.2	-1.4	-1.0
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.6	-0.9	-0.5	-1.0	1.3	-1.0	-0.1	-0.5	-1.0	-0.9
Neuroticism (Nagel 2018)	0.5	1.3	3.4	-0.9	0.5	-1.9	-0.1	-1.6	-0.9	-0.5	-1.5	-0.9
Schizophrenia (2018)	1.2	2.5	7.7	-1.7	-1.5	-1.4	-1.3	-1.4	-2.8	-0.2	-1.7	0.8
Schizophrenia vs Biploar Disorder	0.8	1.1	1.9	-1.0	1.2	-1.3	-0.3	-1.4	-0.2	-1.0	-1.2	-1.2
Worry (Nagel 2018)	0.3	0.5	1.4	-0.6	-0.0	-1.1	-0.5	-1.2	-0.3	0.5	-1.0	0.4
Alzheimer’s Disease (in mother)	0.2	0.2	0.5	-0.5	0.2	-0.7	-0.6	-0.4	-0.3	0.1	-0.5	0.2
Alzheimer’s Disease (in father)	0.4	0.4	0.9	-0.9	0.3	-0.9	-0.4	-0.5	-0.6	-0.7	-0.6	-0.3
Alzheimer’s Disease (including proxy)	0.8	1.2	2.4	-1.3	-0.3	-1.5	-1.0	-1.3	-1.3	-0.2	-1.4	0.1
Crohns Disease (2017)	0.1	0.2	1.1	0.5	-0.1	0.4	0.0	0.5	1.0	0.5	0.4	0.1
Irritable Bowel Disease (IBD)	0.6	1.5	4.1	1.3	-0.2	1.0	-0.4	1.1	1.3	2.0	1.2	1.6
Ulcerative Colitis (UC)	1.7	3.1	8.5	1.9	-0.4	1.5	-1.1	1.3	1.1	2.9	1.7	2.6
Major Depression (MDD)	1.4	1.7	4.4	-0.5	-1.3	-1.2	2.1	-1.7	-0.8	-0.4	-1.6	-1.2
Reaction Time	0.2	0.4	1.3	-0.1	-0.1	0.4	1.0	1.1	1.0	-0.3	0.6	0.0
Verbal and Numeric Reasoning (VNR)	0.8	1.8	2.8	-1.7	-1.0	-1.4	1.3	-1.3	-0.7	-1.6	-1.7	-1.3
Breast Cancer	1.9	4.7	8.5	-2.1	-0.6	-2.6	0.2	-2.9	-0.9	-2.8	-2.5	-2.7
Ovarian Cancer	0.3	0.4	1.9	-0.7	-0.4	-0.0	-0.6	0.2	-1.4	-0.3	-0.4	0.7
Prostate Cancer	0.8	1.2	4.1	0.8	-0.3	0.9	0.4	1.4	2.0	0.9	1.2	0.7
Age at First Birth	1.1	1.6	5.1	1.2	-2.3	1.2	0.9	1.3	1.1	1.0	1.3	0.7
Bipolar Disorder (2011)	1.1	1.0	3.7	-0.9	-0.2	-0.8	1.9	-1.0	-0.3	-1.0	-0.8	-1.2
Body Mass Index (BMI) (2010)	1.2	1.6	2.6	-1.3	0.9	-1.5	0.7	-1.6	-0.6	-1.4	-1.6	-1.5
Coronary Artery Disease (CAD)	0.9	1.1	2.4	-0.5	1.0	-0.2	1.3	-1.0	-1.5	-1.6	-0.3	-1.0
Crohns Disease (2012)	0.8	1.3	3.7	0.8	-0.1	1.5	-0.5	1.9	1.3	0.9	1.3	1.0
Mean Putamen Volume	0.4	0.4	0.9	0.2	1.0	0.6	-0.9	0.6	0.8	0.3	0.7	0.3
Fasting Glucose	0.9	1.1	5.5	0.1	0.8	-0.3	2.3	-1.1	0.8	-0.5	-0.2	-1.2
HbA1C	0.6	0.6	4.6	0.5	0.1	0.4	2.2	0.3	0.8	0.1	0.0	-0.1
HDL Cholesterol	0.3	0.5	2.0	-0.2	-0.2	-0.8	-0.4	-1.4	-0.3	0.1	-1.0	-0.6
LDL Cholesterol	1.2	1.9	5.2	1.1	-0.9	1.4	-2.3	1.8	-0.5	0.9	1.2	1.6
Lupus	0.1	0.2	0.4	0.5	-0.1	0.1	-0.1	0.5	0.1	0.6	0.5	0.6
Neuroticism (2016)	1.5	2.1	5.6	-1.4	0.3	-2.0	-0.1	-2.4	-1.5	-0.2	-2.1	-0.8
Primary Biliary Cirrhosis	0.6	0.9	4.2	0.8	0.6	0.5	2.1	0.6	1.3	0.5	0.6	-0.3
Rheumatoid Arthritis	2.8	3.8	8.0	-2.8	2.0	-2.3	0.7	-1.3	-1.7	-2.2	-1.9	-1.9
Schizophrenia (2014)	0.9	1.9	3.8	-1.7	-1.8	-1.5	-0.4	-1.5	-1.9	-0.5	-1.5	0.2
Triglycerides	0.3	0.4	1.9	-0.1	0.2	0.9	-0.0	1.4	0.1	0.1	0.9	0.7
Type 2 Diabetes (T2D) (2012)	0.6	0.7	1.6	0.4	-0.3	0.6	-0.8	0.8	0.7	1.3	0.8	1.2
Ulcerative Colitis	1.5	2.1	4.0	1.6	-0.5	1.3	0.4	1.6	2.0	1.9	1.8	1.2
Blood Eosinophil Count	0.0	0.3	1.1	0.0	0.4	-0.2	-0.9	-1.1	-0.6	-0.1	-0.7	-0.1
Blood Platelet Count	0.3	3.9	12.7	-0.3	3.6	-0.2	-3.1	-0.8	-1.2	1.8	-0.7	2.6
Blood Red Count	0.8	7.9	17.6	-2.8	1.9	-2.9	3.7	-2.0	1.3	-3.0	-2.3	-4.2
Blood White Count	1.3	9.7	17.7	-3.1	4.2	-3.0	3.3	-2.9	-1.1	-3.2	-3.1	-3.5
Heel T-Score	0.1	0.7	5.6	-0.4	-2.4	0.1	0.3	0.0	0.2	-0.2	0.0	-0.5
BMI	0.2	1.0	3.5	0.5	1.1	-0.4	1.5	-0.4	0.7	-0.9	0.0	-1.9
Height	0.8	15.7	30.8	4.0	-5.5	4.3	-2.0	3.7	1.0	4.6	3.6	4.8
Waist Hip Ratio (WHR)	0.5	2.1	5.3	1.1	0.8	1.0	-1.1	1.1	1.5	2.3	0.6	2.3
Systolic Blood Pressure	0.2	1.2	3.2	-0.4	1.1	-0.7	-1.8	-1.1	-1.2	0.9	-1.1	1.1
Smoking Status	0.3	0.8	4.0	0.7	2.0	0.7	-0.6	0.3	0.1	0.4	0.9	0.6
Allergy or Eczema	2.0	5.2	11.6	2.0	-1.9	1.8	-3.0	1.9	0.5	2.9	1.7	3.4
Cardiovascular Disease	0.3	1.1	4.5	1.3	-0.6	0.7	0.0	0.5	2.1	1.3	0.8	0.5
Hypothyroidism (self reported)	0.2	0.4	1.9	-0.0	0.1	-0.6	-0.5	-1.4	0.9	0.1	-0.5	-0.6
Respiratory disease	0.3	0.7	4.3	0.1	-0.4	0.2	-2.1	0.1	-0.3	0.7	0.1	1.2
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.9	0.9	0.1	0.7	-0.4	-0.2	-0.1	0.5	0.3	0.3
Lung FEV1/FVC ratio	0.2	1.2	2.1	0.6	1.4	0.8	1.1	1.1	1.4	-1.1	1.2	-1.2
Lung FVC	0.2	1.2	4.5	-0.5	-2.1	-0.2	1.4	-0.5	-1.4	-1.2	-0.3	-0.8
Neuroticism	1.1	2.6	5.8	-1.3	0.9	-2.3	0.4	-2.4	-0.9	-0.9	-2.1	-1.8
Chronotype (morning person)	0.6	1.4	3.3	-1.8	-0.7	-1.5	1.2	-0.2	-0.7	-1.1	-1.3	-1.2
Hair Pigment	0.1	1.8	4.8	-1.1	2.2	-1.5	0.9	-1.6	-0.4	-1.0	-1.5	-0.9
Tanning	0.2	2.2	4.1	-0.8	1.7	-1.2	1.0	-1.8	-1.2	-2.0	-1.1	-2.0
Hand grip strength (left)	0.4	0.9	2.5	-1.0	1.2	-0.8	0.1	-0.5	-1.6	-1.0	-0.6	-1.1
Number of treatments/medications taken	0.3	0.5	1.1	0.4	0.2	-0.3	-1.0	-0.9	0.9	1.1	-0.4	0.5
Average weekly spirits intake	0.4	0.5	2.0	-0.1	1.0	-0.0	-0.6	0.2	0.5	-1.4	0.1	-1.1
Sensitivity / hurt feelings	0.8	1.3	1.9	-1.3	-0.7	-1.4	0.3	-1.3	-0.7	-1.2	-1.4	-1.4
Frequency of depressed mood in last 2 weeks	0.8	1.1	2.9	-0.9	0.3	-1.6	-0.4	-1.7	-0.4	-0.4	-1.5	-1.0
Hearing difficulty/problems: Yes	0.3	0.4	1.2	-0.6	-1.1	-0.3	0.0	0.1	-0.9	-1.1	0.1	-0.2
Relative age of first facial hair	3.4	7.0	14.0	-3.0	0.6	-2.8	1.9	-2.8	-1.5	-3.7	-2.5	-3.6
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.5	-0.5	-0.5	-0.7	0.1	-0.7	0.2	-0.4	-0.5	-0.6
Ever used hormone-replacement therapy (HRT)	0.9	1.1	3.7	-0.6	-0.5	-1.4	0.5	-1.9	-1.0	-0.3	-1.4	-0.9
Ever had hysterectomy (womb removed)	4.7	5.3	10.7	-2.8	1.9	-3.2	0.9	-2.9	-1.4	-1.1	-3.3	-1.7
Systolic blood pressure, automated reading	0.3	1.0	2.8	0.2	1.5	0.1	-1.7	-0.2	-0.7	1.2	-0.2	1.4
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.2	-0.9	0.6	-0.7	1.1	-0.7	-0.6	-1.1	-0.7	-0.9
Angina	0.4	0.5	1.7	0.7	0.5	0.7	-1.3	0.9	0.2	0.3	0.8	0.2
Medication for hormone replacement therapy	1.5	1.7	4.4	-1.2	0.0	-1.7	-1.0	-1.5	-2.1	-0.2	-1.7	0.2
Vitamin and mineral supplements	0.2	0.3	1.2	0.8	0.2	0.1	0.2	-0.1	1.1	0.8	0.4	-0.0
Supplements: Zinc	0.5	0.5	1.5	-0.2	-0.5	-0.3	-0.7	-0.5	-0.3	1.2	-0.7	1.2
Medication: Co-codamol	0.9	1.1	3.5	1.7	0.3	0.7	-0.4	0.7	1.9	1.0	1.1	0.1
Medication: Metformin	0.1	0.1	0.4	0.2	0.6	-0.1	0.5	-0.6	0.1	0.2	-0.2	-0.3
Diabetes (father)	0.6	0.7	1.9	1.4	-0.2	0.8	-0.1	0.0	1.1	1.4	0.4	0.7
Diabetes (mother)	0.3	0.3	0.8	0.8	0.8	0.3	-0.9	-0.1	0.7	0.5	0.4	0.2
Severe depression (siblings)	6.1	6.8	11.3	-3.1	1.2	-3.4	0.2	-3.1	-3.3	-2.1	-3.1	-2.1
Pack years adult smoking proportion	0.6	1.0	2.9	-1.0	0.8	-1.3	-1.7	-1.0	-0.4	-0.1	-1.2	-0.1
Impedance of leg (right)	1.1	5.4	9.9	2.1	-1.5	2.1	-2.8	2.3	1.3	2.9	2.1	3.1
Leg fat-free mass (left)	0.2	0.9	3.1	-0.0	-0.4	-0.3	1.4	-0.8	-0.8	-1.4	-0.2	-1.8
Trunk fat percentage	0.7	2.7	7.2	2.7	-0.2	1.5	0.4	1.5	2.3	1.3	2.2	0.1
Hand grip strength (right)	0.2	0.6	3.5	0.2	0.5	0.4	-1.9	0.2	-0.6	0.7	0.3	0.8
Townsend deprivation index at recruitment	0.4	0.5	2.3	-0.2	1.5	-1.0	-0.2	-0.9	0.0	0.5	-0.6	-0.2
Current tobacco smoking	0.2	0.4	1.6	-0.3	0.6	-0.2	-0.9	-0.0	-1.2	-0.2	-0.3	0.4
Average weekly fortified wine intake	2.0	2.4	4.3	-2.0	1.0	-1.7	0.3	-1.2	-2.1	-1.8	-1.8	-1.1
Maternal smoking around birth	0.2	0.3	2.3	0.1	1.5	0.2	-0.5	-0.1	-0.5	-0.3	0.0	-0.2
Fed-up feelings	0.5	0.9	2.2	-0.7	0.8	-1.5	-0.4	-1.2	-0.8	-0.4	-1.2	-1.0
Frequency of unenthusiasm / disinterest in last 2 weeks	2.3	3.0	6.0	-1.5	0.8	-2.3	-0.2	-2.5	-1.6	-1.3	-2.2	-1.9
Relative age voice broke	2.9	4.4	8.7	-1.7	0.5	-2.3	2.0	-2.9	0.3	-2.0	-2.4	-2.9
Taking other prescription medications	1.3	2.0	6.0	1.6	-1.3	0.8	-0.6	0.3	1.8	2.5	0.8	1.6
Age when periods started (menarche)	0.4	1.1	3.1	-0.8	-1.5	-0.1	1.8	-0.3	-0.3	-1.3	0.0	-1.3
Bilateral oophorectomy (both ovaries removed)	3.0	3.4	6.3	-2.2	1.6	-2.5	1.0	-2.1	-0.7	-1.4	-2.3	-1.9
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.2	0.1	-1.5	0.7	-0.1	0.7	0.9	0.5	0.7	0.5
Tinnitus: Yes, but not now, but have in the past	0.2	0.3	0.9	-0.2	0.4	-0.4	-0.6	-0.1	-0.9	0.5	-0.1	0.6
Qualifications: CSEs or equivalent	0.8	1.0	5.1	1.1	2.3	1.1	0.2	0.7	-0.1	0.5	0.9	0.4
Serious illness, injury or assault to yourself	0.2	0.3	0.8	0.1	-0.5	0.5	-0.2	0.9	-0.1	0.3	0.6	0.7
High blood pressure	0.3	0.8	2.1	-0.5	-0.3	-1.1	-0.6	-0.7	1.2	1.4	-0.9	0.8
Hayfever, allergic rhinitis or eczema	1.2	2.6	6.6	1.3	-1.7	1.1	-2.6	1.0	-0.1	1.9	1.0	2.3
Multivitamins +/- minerals	0.4	0.6	2.5	-0.2	0.1	0.9	-0.1	1.6	-0.8	-0.4	0.7	0.6
Stomach or abdominal pain in last month	0.6	0.7	2.4	1.0	-0.5	0.5	-0.6	0.6	0.5	1.6	0.6	1.0
Supplements: Glucosamine	1.7	2.2	4.2	-1.0	0.0	-1.6	2.0	-2.1	0.4	-1.0	-1.8	-1.9
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.5	0.2	0.6	0.1	-0.2	-0.0	-0.7	0.5	0.1	0.4
Medication: Atenolol	0.4	0.5	1.2	0.9	0.4	0.6	0.5	0.7	1.1	0.7	0.9	0.5
Medication: Levothyroxine sodium	0.4	0.6	2.3	0.5	0.4	-0.6	-0.1	-0.9	1.5	1.3	-0.4	0.2
Sitting height	0.8	5.9	16.5	2.3	-4.1	3.1	-0.4	2.7	0.2	1.4	3.0	1.8
Chronic bronchitis/emphysema (father)	0.4	0.4	1.0	-0.6	0.0	-0.6	0.0	-0.8	-1.0	-0.8	-0.4	-0.9
High blood pressure (mother)	0.3	0.4	1.7	0.3	1.3	0.8	0.3	0.7	0.8	-0.3	0.5	-0.3
Body mass index (BMI)	0.2	0.9	2.8	0.8	1.7	-0.1	1.2	-0.2	1.1	-0.3	0.3	-1.4
Impedance of leg (left)	1.3	6.3	10.1	2.5	-1.2	2.5	-2.9	2.6	1.6	2.9	2.6	3.2
Leg predicted mass (left)	0.2	1.0	3.5	-0.1	-0.4	-0.3	1.5	-0.8	-0.7	-1.4	-0.3	-1.9
Trunk fat mass	0.5	2.3	6.6	2.6	-0.4	1.5	0.6	1.3	2.1	1.1	2.1	-0.2
Waist circumference	0.1	0.5	1.7	1.3	0.4	0.4	0.7	0.3	1.1	0.6	0.7	-0.4
Number of incorrect matches in round	1.3	2.1	5.9	1.0	-0.4	1.8	-0.1	1.6	0.2	2.0	1.4	2.4
Past tobacco smoking	0.6	1.1	8.2	0.1	-2.9	0.3	1.1	0.6	-0.3	-0.1	-0.0	-0.3
Alcohol usually taken with meals	1.1	1.8	7.5	0.7	-2.7	0.7	-1.7	0.6	-0.9	0.8	0.4	1.6
Nervous feelings	0.3	0.6	2.0	0.1	-0.8	0.1	-0.4	-0.6	-0.1	1.4	-0.5	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	3.9	-0.2	-0.8	-1.4	-0.8	-2.0	0.2	0.3	-1.2	-0.6
Hearing difficulty/problems with background noise	0.6	1.0	8.0	0.2	-2.8	-0.1	0.1	-0.4	-0.6	0.2	-0.1	-0.1
Hair/balding pattern: Pattern 2	0.3	0.4	1.1	-0.1	0.7	0.8	-0.2	0.8	0.3	0.5	0.2	1.0
Had menopause	0.2	0.3	1.0	0.5	-0.5	0.1	-0.3	0.1	-0.3	1.0	0.3	0.8
Had other major operations	1.4	1.7	6.1	-0.8	0.3	-0.6	0.9	-0.6	-1.2	-2.3	0.1	-2.5
Forced vital capacity (FVC)	0.2	0.8	5.5	0.7	-2.3	0.5	0.1	0.0	-1.0	0.3	0.4	0.3
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.6	-0.5	-1.2	-0.4	0.6	-0.7	0.5	-0.6	-0.2	-1.0
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	0.8	0.4	-0.8	-0.2	-0.9	-0.8	-0.2	0.9	-0.6	0.7
Qualifications: None of the above	0.4	0.9	2.0	1.2	0.9	0.5	-0.6	0.7	1.3	1.4	0.8	0.9
Financial difficulties in last 2 years	0.6	0.8	3.2	-0.9	-0.6	-1.3	-1.8	-0.5	-0.2	-0.5	-0.9	-0.0
Mouth/teeth dental problems	0.8	1.3	3.5	0.9	-0.6	1.7	0.9	1.9	0.1	0.6	1.5	0.9
Heart attack	2.6	3.3	8.0	-1.7	1.0	-2.1	1.4	-1.9	-0.2	-2.2	-1.7	-2.8
Allergy	0.6	1.5	5.9	-0.9	0.7	-0.5	2.4	-0.3	0.5	-1.4	-0.4	-1.7
Pain all over the body in last month	1.0	1.1	3.6	1.1	0.0	0.6	-0.6	0.3	1.1	1.9	0.4	1.5
Diabetes (self-reported)	0.1	0.1	0.3	0.6	0.0	0.5	-0.2	0.0	0.3	0.0	0.4	0.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	2.7	-1.3	-0.1	-1.2	-0.9	-1.3	-1.6	0.3	-1.3	0.6
Medication: Ramipril	0.4	0.6	0.9	-0.9	-0.3	-1.0	0.7	-0.7	1.0	-0.5	-0.5	-0.9
Medication: Simvastatin	0.1	0.2	1.1	0.6	0.1	0.1	0.2	-0.2	1.0	-0.0	0.2	-0.5
Fluid intelligence score	1.0	2.2	3.5	-1.6	-0.8	-1.6	1.2	-1.4	-0.7	-1.9	-1.7	-1.8
Illnesses of siblings	1.3	1.8	4.2	-1.3	-0.9	-1.1	1.5	-1.0	-2.1	-1.2	-1.3	-1.3
Neuroticism score	2.0	4.2	9.6	-1.8	0.8	-3.0	0.5	-3.1	-0.9	-1.2	-2.8	-2.3
Weight	0.2	0.8	2.7	1.6	-0.4	0.9	0.9	0.5	0.8	0.3	1.2	-0.6
Impedance of arm (right)	0.3	1.6	3.0	1.0	-1.6	1.3	-0.7	1.6	0.3	1.3	1.2	1.7
Arm fat percentage (right)	0.2	0.9	2.0	1.2	1.4	0.2	1.4	0.2	1.2	0.1	0.7	-1.1
Trunk fat-free mass	0.1	0.6	1.6	-0.1	-0.7	-0.3	1.0	-0.8	-0.8	-1.0	-0.3	-1.3
Hip circumference	0.3	1.1	4.1	0.4	0.3	-0.2	2.0	-0.3	0.2	-1.2	0.3	-2.0
Time employed in main current job	0.3	0.3	1.3	-0.4	0.1	0.2	0.6	0.3	-0.2	-1.2	0.3	-0.9
Alcohol intake versus 10 years previously	0.4	0.5	3.1	0.5	1.8	0.5	0.4	-0.0	0.8	0.5	0.2	-0.0
Father’s age at death	0.6	0.8	2.1	1.0	-1.2	1.2	-0.1	0.7	0.3	0.2	1.4	0.4
Worrier / anxious feelings	0.1	0.3	0.8	-0.2	-0.5	-0.8	-0.3	-0.9	0.0	0.4	-0.6	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	2.5	0.9	-1.6	0.8	-1.5	0.5	0.6	1.2	0.7	1.3
Falls in the last year	0.5	0.6	1.7	-0.7	0.1	-1.2	-0.4	-1.1	-0.5	0.5	-1.3	-0.0
Hair/balding pattern: Pattern 3	0.7	1.1	2.5	-1.6	-0.4	-1.2	-0.1	-1.3	-1.1	-0.7	-1.4	-0.2
Number of live births	0.1	0.2	0.6	-0.2	0.3	-0.6	0.3	-0.0	0.4	-0.6	-0.2	-0.8
Forced expiratory volume in 1-second (FEV1)	0.2	0.8	2.8	0.9	-1.7	0.8	1.0	0.3	-0.6	-0.4	0.8	-0.5
Pulse rate	0.5	0.8	1.6	0.6	-0.1	1.3	-0.2	1.2	-0.0	0.9	1.1	1.3
Happiness	0.7	0.9	4.4	0.4	-2.1	0.2	-1.2	-0.0	-0.9	0.5	0.1	0.7
Noisy workplace	1.1	1.3	2.5	0.7	0.5	1.4	-1.0	1.5	-0.0	1.1	1.5	1.6
Qualifications: A levels/AS levels or equivalent	0.4	0.9	3.6	-0.4	-1.9	-0.6	0.5	-1.0	-0.1	-1.2	-0.5	-1.1
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.3	3.8	-1.9	0.2	-1.0	-0.7	-0.3	-1.9	-1.2	-0.9	-0.5
Mouth/teeth dental problems: Dentures	0.0	0.1	0.1	0.0	-0.3	-0.3	-0.1	-0.1	-0.3	0.3	-0.3	0.4
Asthma	0.2	0.5	0.9	-1.0	0.4	-0.8	-0.8	-0.7	-0.8	-0.4	-0.8	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	1.5	1.1	-0.1	1.0	-1.2	0.7	0.6	0.7	0.8	0.9
Medication: Cholesterol lowering	0.7	1.0	2.0	-0.5	1.2	-1.0	0.7	-1.4	1.1	-0.7	-0.8	-1.4
Depression (self-reported)	0.6	0.8	1.9	0.0	-0.1	-0.9	-1.0	-1.3	-0.1	1.4	-1.1	0.4
Medication: Lansoprazole	0.8	0.9	3.5	0.0	1.8	-0.8	-1.9	-0.5	0.4	0.8	-0.2	0.2
Prospective memory result	1.0	1.3	2.4	1.5	0.3	1.0	-0.6	1.0	1.5	1.4	1.4	0.6
Lung cancer (father)	1.5	1.7	6.4	-0.9	2.5	-1.4	-0.2	-1.4	-1.0	-0.8	-1.4	-0.9
Illnesses of mother	1.1	1.4	4.4	-0.8	-2.1	-0.8	-1.9	-0.3	-1.6	0.2	-0.4	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	1.4	1.0	-1.1	1.2	1.0	1.0	-0.2	0.0	1.1	-0.0
Pulse wave Arterial Stiffness index	1.1	1.3	3.2	0.9	-1.5	1.4	-1.8	1.0	-0.0	0.2	1.3	0.9
Impedance of arm (left)	0.4	1.8	3.6	1.0	-1.9	1.4	-1.1	1.6	0.1	1.1	1.3	1.7
Arm fat mass (right)	0.1	0.6	1.6	1.3	1.0	0.3	1.0	-0.0	0.7	0.2	0.6	-0.9
Trunk predicted mass	0.1	0.6	1.6	-0.1	-0.7	-0.3	0.9	-0.8	-0.9	-0.9	-0.3	-1.2
Standing height	0.5	5.2	18.0	2.3	-4.2	2.6	-1.0	2.0	-0.1	1.6	2.4	1.9
Length of working week for main job	0.4	0.4	1.3	-0.7	0.6	-0.5	-0.7	0.0	-0.7	-1.1	-0.2	-0.3
Exposure to tobacco smoke at home	2.5	2.8	6.5	2.3	-0.9	1.7	0.3	1.7	2.5	1.5	1.9	0.8
Breastfed as a baby	0.6	0.8	2.6	-0.1	0.5	-0.7	1.3	-1.1	0.5	-0.7	-0.3	-1.6
Tense / ‘highly strung’	1.2	2.0	4.4	-1.4	-0.0	-1.7	-1.1	-1.9	-1.6	0.7	-2.1	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	2.6	3.9	8.5	-2.9	0.6	-2.9	-0.9	-2.4	-1.5	-0.8	-2.8	-0.8
Hair/balding pattern: Pattern 4	0.2	0.5	1.1	0.4	-1.0	0.0	0.7	0.4	-0.4	-1.0	0.7	-1.1
Birth weight of first child	0.3	0.6	1.8	1.2	-0.0	0.2	1.2	-0.3	0.6	-0.7	0.2	-1.4
Peak expiratory flow (PEF)	0.5	1.2	2.2	1.1	-1.2	1.4	1.1	1.0	0.6	-0.7	1.5	-0.8
Pulse wave reflection index	0.2	0.3	1.5	0.1	-0.8	0.0	-1.2	-0.3	-0.4	-0.2	-0.1	0.2
Ever highly irritable/argumentative for 2 days	0.9	1.1	2.2	1.4	-0.7	1.0	-0.9	0.6	1.5	1.1	1.0	0.8
Loud music exposure frequency	0.6	0.6	2.1	-0.4	0.2	0.5	-0.9	0.6	-1.1	0.7	0.0	1.5
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	2.2	-1.2	-0.7	-1.2	-0.8	-1.5	-0.9	-0.7	-1.1	-0.6
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.1	0.4	0.8	-0.2	-1.5	-0.4	1.2	0.8	0.0	0.4
Blood clot in the leg (DVT)	0.4	0.5	2.1	0.4	0.6	0.4	0.8	0.5	1.5	0.5	0.5	0.4
Medication: Paracetamol	0.7	1.1	2.6	0.9	1.0	1.1	-1.0	0.8	0.5	1.3	0.9	1.6
Headache pain in last month	3.1	5.3	8.1	2.6	-0.4	2.8	-1.6	2.7	1.8	2.2	2.8	2.6
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	5.2	0.1	-0.6	0.8	-1.4	1.0	-2.3	-0.4	0.5	0.8
Glaucoma (self-reported)	0.2	0.2	0.5	0.4	-0.6	0.1	0.7	0.2	0.6	-0.2	0.4	-0.2
Gout (self-reported)	0.6	0.9	3.3	0.6	1.8	-0.2	1.2	-0.2	1.1	0.0	0.1	-1.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.7	-0.1	0.4	-0.7	-0.7	-1.3	1.3	0.8	-0.7	0.2
Medication: Amlodipine	1.1	1.5	3.2	0.8	-0.3	1.1	-1.8	1.1	0.9	1.4	1.1	1.8
Medication: Ventolin 100micrograms inhaler	1.5	1.9	4.7	1.5	0.1	0.9	-1.4	0.9	2.2	2.0	1.0	1.5
Birth weight	0.7	1.6	6.2	0.7	-2.5	-0.2	2.5	-0.2	0.3	-0.2	0.2	-1.0
Chronic bronchitis/emphysema (mother)	1.2	1.4	5.7	-1.0	2.4	-0.7	0.8	-0.8	-0.1	-1.3	-0.8	-1.3
High blood pressure (siblings)	0.9	1.3	5.9	1.0	0.2	0.9	-2.4	0.9	0.7	0.8	1.1	1.0
Forced vital capacity (FVC), Best measure	0.2	0.9	3.8	0.8	-1.9	0.9	0.3	0.6	-0.9	0.4	0.7	0.5
Body fat percentage	0.5	2.0	5.9	2.4	0.3	1.2	0.3	1.2	2.1	1.1	1.9	-0.2
Leg fat percentage (right)	0.4	1.5	4.4	2.1	0.6	1.0	-0.5	0.9	1.7	1.2	1.6	0.1
Arm fat-free mass (right)	0.0	0.2	0.9	0.6	-0.3	0.0	0.6	-0.5	0.2	-0.2	0.2	-0.9
Exposure to tobacco smoke outside home	0.7	0.9	1.9	-0.0	1.4	-0.9	1.4	-0.9	0.9	-0.4	-0.7	-1.3
Comparative body size at age 10	2.0	5.4	12.7	-1.5	0.4	-2.6	1.9	-2.9	-1.7	-2.7	-2.1	-3.6
Number of full brothers	0.3	0.4	2.1	-0.3	0.0	0.1	-1.4	0.7	-0.2	-0.1	0.6	0.2
Worry too long after embarrassment	1.7	2.9	6.8	-1.8	0.4	-2.6	0.4	-2.5	-0.2	-0.6	-2.6	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	2.0	2.6	5.0	-2.2	-0.1	-2.2	-1.4	-1.8	-2.1	-0.8	-2.0	-0.3
Wheeze or whistling in the chest in last year	0.5	0.9	5.3	0.3	-0.3	-0.3	-2.3	-0.4	-1.1	0.9	-0.2	0.9
Number of children fathered	1.6	1.8	3.0	-1.3	-1.4	-1.4	0.9	-1.1	-0.8	-1.7	-1.4	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	1.8	-0.7	1.3	-1.0	0.6	-1.2	-1.2	-0.9	-1.1	-0.9
Age at first live birth	0.6	1.1	3.9	1.0	-1.3	0.7	-0.0	0.9	2.0	0.8	0.9	0.3
Pulse wave peak to peak time	0.8	0.9	2.5	-0.7	1.1	-1.2	1.6	-0.9	-0.1	-0.0	-1.1	-0.7
Health satisfaction	0.4	0.6	1.5	0.8	-0.0	0.6	-1.1	0.1	-0.3	1.1	0.4	1.2
Shortness of breath walking on level ground	0.2	0.3	1.0	0.2	-0.4	0.5	-1.0	0.2	-0.8	-0.4	0.5	0.1
Qualifications: College or University degree	0.2	0.5	1.2	-0.8	-1.1	0.2	-1.0	0.2	-1.0	-0.9	-0.1	0.1
Eye problems/disorders: None of the above	0.4	0.4	1.3	-0.6	0.7	-0.6	0.4	-0.5	-0.2	-0.8	-0.7	-1.1
Mouth/teeth dental problems: Loose teeth	1.2	1.5	3.7	1.6	-0.3	0.6	-1.2	1.0	1.9	1.0	1.5	0.8
Emphysema/chronic bronchitis	0.5	0.5	1.6	0.0	-1.2	-0.3	-1.2	-0.0	0.3	1.0	-0.1	0.8
Medication for pain relief, constipation, heartburn	1.2	2.0	3.4	-1.6	-1.0	-1.2	1.5	-0.7	-1.8	-1.8	-1.0	-1.6
Neck or shoulder pain in last month	0.8	1.1	1.7	1.3	1.3	1.2	0.5	1.0	0.8	1.3	1.0	1.0
Medication: Blood pressure	0.4	0.7	2.0	-0.4	0.5	-1.1	1.0	-0.8	1.4	0.7	-0.6	-0.2
Angina (self-reported)	0.6	0.8	1.9	1.0	0.4	1.0	-1.4	1.1	0.6	0.3	1.1	0.3
Migraine (self-reported)	0.2	0.2	1.2	0.4	0.6	0.1	0.5	0.1	1.1	0.5	0.3	0.0
Medication: Ibuprofen	0.5	0.6	2.0	1.0	0.1	1.0	-1.4	0.6	0.2	0.2	0.9	0.7
Medication: Allopurinol	0.7	1.0	3.1	0.6	1.8	-0.2	1.2	-0.3	1.6	0.5	-0.1	-0.7
Medication: Omeprazole	1.3	1.5	3.3	1.5	1.1	1.5	-0.6	0.9	0.3	1.8	0.8	1.7
Medication: Seretide 50 evohaler	0.5	0.6	1.8	0.9	-0.7	0.6	-0.0	0.0	1.0	1.3	0.4	0.9
Mean time to correctly identify matches	0.3	0.6	1.5	0.1	-0.6	0.4	0.8	1.2	1.2	0.4	0.7	0.6
Heart disease (mother)	1.0	1.2	5.4	1.1	2.3	1.0	-1.3	0.3	0.4	0.6	0.8	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.5	3.0	6.1	-1.6	2.5	-2.0	1.6	-1.7	0.3	-1.2	-2.0	-1.8
Whole body fat mass	0.3	1.2	4.1	2.0	0.2	0.9	0.5	0.8	1.5	0.8	1.5	-0.5
Leg fat mass (right)	0.4	1.6	5.4	2.3	0.6	1.2	-0.0	0.9	1.6	1.1	1.6	-0.1
Arm predicted mass (right)	0.0	0.2	0.8	0.5	-0.5	0.1	0.5	-0.4	0.1	-0.3	0.3	-0.9
Pulse rate, automated reading	0.7	2.4	3.9	1.6	-0.9	1.9	-0.8	1.8	0.9	1.7	1.7	2.0
Alcohol intake frequency.	0.1	0.3	0.9	-0.1	0.8	-0.3	0.9	-0.4	0.5	0.5	-0.4	0.0
Comparative height size at age 10	1.3	7.2	13.9	2.8	-3.7	2.7	-2.2	2.2	0.4	3.1	2.5	3.2
Number of full sisters	0.4	0.4	1.3	-0.2	1.2	-0.2	0.6	0.3	0.0	-1.1	0.4	-0.9
Suffer from ‘nerves’	2.4	3.7	8.2	-2.1	0.4	-2.4	0.1	-2.9	-2.3	-0.9	-2.8	-0.8
Overall health rating	0.3	0.6	1.8	0.3	1.4	-0.2	-1.2	-0.1	-0.1	1.0	-0.3	0.9
Chest pain or discomfort	0.8	1.1	2.7	-1.2	-0.7	-1.0	-1.4	-1.0	-1.6	-0.7	-0.9	0.0
Had major operations	1.1	1.3	3.2	0.8	-0.0	1.1	-1.6	1.4	-0.1	1.1	0.9	1.8
Age at last live birth	1.3	1.9	3.1	1.5	-1.7	1.5	0.6	1.6	1.7	0.8	1.7	0.7
Family relationship satisfaction	0.2	0.3	0.9	0.1	-0.4	-0.4	0.2	-0.9	-0.5	0.4	-0.8	0.1
Leg pain on walking	1.0	1.3	6.3	-0.0	2.5	-0.3	1.0	-0.5	-0.3	-1.1	-0.1	-1.5
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	3.8	-0.5	0.2	-0.6	0.9	-1.3	-0.4	-1.6	-0.6	-2.0
Commuting to job workplace: Car/motor vehicle	0.3	0.4	1.2	-0.0	0.5	0.6	-0.5	1.1	0.4	-0.1	0.8	0.8
Illness, injury, bereavement, stress in last 2 years	1.8	2.2	4.9	2.2	-0.1	1.6	1.5	1.1	1.5	1.9	1.5	1.0
Medication: Aspirin	0.2	0.2	0.9	0.4	0.4	0.4	-0.5	-0.1	0.9	0.4	0.1	0.2
Supplements: Vitamin C	1.1	1.4	3.6	-1.2	-0.7	-1.3	-0.7	-1.9	-1.3	-0.6	-1.5	-0.4
Knee pain experienced in last month	0.3	0.5	1.1	-0.7	1.1	-0.4	0.8	-0.1	-1.1	-0.6	-0.4	-0.1
Hypertension (Self-reported)	0.3	0.9	3.6	0.2	-0.4	-0.4	-0.6	-0.1	1.6	1.9	-0.3	1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	2.2	1.5	0.8	1.0	0.0	0.3	1.4	1.3	0.8	0.8
Illnesses of father: Heart disease	0.8	1.1	2.5	0.9	0.2	0.7	-1.5	0.9	0.6	1.5	0.5	1.6
Illnesses of siblings: Diabetes	0.6	0.7	3.0	0.2	1.7	-0.2	0.7	0.3	0.6	-0.9	0.3	-1.1
Smoking status: Previous	0.6	0.9	6.7	0.1	2.6	-0.1	-0.4	-0.5	0.7	0.3	0.4	0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	2.1	1.0	-1.5	0.8	-0.2	0.4	0.5	1.2	0.5	0.6
Whole body fat-free mass	0.2	0.9	2.8	-0.1	-0.6	-0.4	1.3	-0.9	-0.7	-1.2	-0.3	-1.7
Leg fat-free mass (right)	0.2	1.1	3.5	-0.1	-0.3	-0.2	1.5	-0.8	-0.7	-1.5	-0.2	-1.9
Arm fat percentage (left)	0.2	0.9	1.6	1.2	1.3	0.2	1.3	0.1	1.2	-0.1	0.7	-1.3
Average weekly red wine intake	0.5	0.7	2.3	-0.6	-1.0	-0.4	-1.0	-0.6	-1.5	0.0	-0.6	0.7
Handedness (chirality/laterality): Left-handed	0.5	0.7	2.1	0.8	-1.1	0.7	0.3	0.5	0.2	1.4	0.4	0.9
Mood swings	0.2	0.3	1.6	0.7	-0.5	0.0	-1.3	-0.2	0.3	0.5	0.2	0.1
Loneliness, isolation	1.4	1.9	3.4	-1.1	-1.3	-1.5	-0.1	-1.9	-1.1	-1.6	-1.6	-1.6
Long-standing illness, disability or infirmity	1.1	1.7	3.3	1.1	-0.8	1.0	-1.8	0.7	1.2	1.7	1.0	1.8
Ever had bowel cancer screening	0.9	1.0	3.1	0.4	-1.8	0.1	-1.5	0.4	0.2	1.3	0.1	1.3
Diabetes diagnosed by doctor	0.0	0.1	0.4	0.3	0.3	-0.1	0.0	-0.6	-0.2	0.1	-0.2	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	2.2	0.8	-1.3	1.1	-0.1	1.5	0.3	0.2	1.2	0.5
Friendships satisfaction	0.1	0.2	1.0	0.1	-1.0	0.0	0.2	-0.5	-0.3	-0.1	-0.1	-0.1
Qualifications: nursing, teaching	0.1	0.2	1.6	0.3	-1.3	0.4	0.1	0.1	-0.1	0.3	0.1	0.2
Commuting to job workplace: Walk	0.7	0.8	2.1	-1.1	-0.4	-0.6	-0.0	-1.0	-1.4	-0.9	-1.0	-0.7
Eye problems/disorders: Cataract	0.1	0.2	0.6	0.0	-0.5	0.1	0.8	0.5	0.1	0.2	0.4	0.3
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	2.9	-0.5	0.9	-0.4	-0.7	-1.4	-1.3	-1.7	-0.5	-1.3
Medication for cholesterol	0.3	0.4	1.8	-0.4	0.7	-0.2	0.6	0.1	1.3	-0.6	0.1	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.6	1.2	-0.6	0.7	0.8	-0.1	0.7	-0.0	0.7	-0.4
Back pain experienced in last month	0.7	1.1	2.0	1.3	0.4	1.1	-0.3	0.6	1.2	1.4	0.8	1.4
Mineral and other dietary supplements	1.8	2.5	4.2	1.9	-0.3	1.7	-1.3	1.8	1.0	1.6	2.0	1.6
Breast cancer (self-reported)	0.3	0.3	0.7	0.8	0.1	0.8	-0.4	0.4	0.1	0.5	0.6	0.8
Asthma (self-reported)	0.2	0.4	0.6	-0.7	0.8	-0.6	-0.7	-0.5	-0.7	-0.2	-0.7	0.1
Osteoporosis (self-reported)	1.0	1.2	2.2	1.2	-1.5	1.2	-1.2	1.0	0.7	0.3	1.5	0.5
Osteoarthritis (self-reported)	0.3	0.3	1.4	0.6	1.2	0.6	-0.3	0.2	-0.5	0.3	0.4	0.6
Medication: Aspirin	0.1	0.1	0.2	-0.1	0.2	0.1	0.0	-0.4	0.5	-0.3	-0.2	-0.3
Medication: Gliclazide	1.7	1.9	3.8	1.7	-0.9	1.6	-0.7	1.7	1.5	0.9	1.9	0.9
Illnesses of father: None of the above (group 1)	0.3	0.4	0.9	0.6	-0.0	0.7	0.9	0.9	0.3	-0.0	0.8	0.1
Smoking status: Current	0.1	0.2	0.7	-0.1	0.6	-0.1	-0.8	0.0	-0.8	-0.0	-0.2	0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	5.3	1.1	-0.6	1.4	2.3	2.0	2.2	-0.0	1.8	-0.4
Whole body water mass	0.1	0.9	2.7	-0.1	-0.6	-0.4	1.3	-0.9	-0.7	-1.2	-0.3	-1.6
Leg predicted mass (right)	0.2	1.1	3.6	-0.1	-0.3	-0.3	1.5	-0.7	-0.7	-1.6	-0.2	-1.9
Arm fat mass (left)	0.2	0.7	1.7	1.3	1.0	0.4	0.9	0.1	0.9	0.1	0.8	-1.0
Number of self-reported non-cancer illnesses	1.2	2.1	5.4	1.8	-0.4	1.0	-1.1	0.3	2.3	2.3	1.1	1.2
Average weekly champagne plus white wine intake	1.1	1.5	4.1	1.2	-2.0	1.2	1.0	0.5	1.1	-0.9	1.4	-1.4
Miserableness	2.0	3.5	8.5	-1.5	0.6	-2.4	0.5	-2.2	-1.1	-2.3	-1.7	-2.9
Guilty feelings	1.7	2.6	6.2	-1.4	0.3	-2.0	1.2	-2.0	0.0	-1.6	-1.8	-2.5
Wears glasses or contact lenses	0.3	0.3	0.9	0.1	-0.7	-0.9	-0.9	-0.4	-0.3	0.5	-0.5	0.0
Ever taken oral contraceptive pill	5.1	5.7	14.2	-2.0	-0.7	-1.6	3.1	-2.1	-0.3	-3.7	-1.6	-3.8
Hearing aid user	0.3	0.3	1.1	0.3	1.0	0.4	0.4	0.6	0.6	-0.4	0.8	-0.3
Mother’s age at death	0.3	0.3	1.4	-0.0	-0.9	-0.2	1.2	-0.6	-0.0	-0.0	-0.6	-0.1
Financial situation satisfaction	0.3	0.4	2.9	0.1	-0.1	-0.3	-1.7	-0.4	-0.2	0.3	-0.3	0.6
Tinnitus: Yes, now most or all of the time	0.7	0.8	3.6	-0.7	1.9	-0.2	0.9	-0.2	-0.2	-1.0	-0.1	-1.0
Commuting to job workplace: Public transport	0.5	0.6	1.1	-0.7	-0.3	-0.8	0.3	-1.0	-0.7	-1.0	-0.8	-1.0
Eye problems/disorders: Glaucoma	0.4	0.5	2.6	0.9	-1.6	0.2	0.5	-0.1	0.5	0.1	0.4	-0.0
Medication: Blood pressure	0.3	0.5	2.0	0.5	-0.4	0.2	-0.9	-0.1	-0.3	1.1	-0.2	1.4
Pain type(s) experienced in last month: Hip pain	0.8	1.0	4.1	-0.9	0.2	-0.7	-0.6	-0.7	-2.0	-1.1	-1.0	-0.2
Supplements: Fish oil (including cod liver oil)	1.0	1.3	2.7	-1.4	0.1	-1.0	0.8	-1.3	-1.6	-0.9	-1.6	-0.7
High cholesterol (Self-reported)	0.2	0.4	1.4	1.0	-0.3	0.5	0.3	-0.2	1.2	0.2	0.6	-0.4
Medication: Bendroflumethiazide	0.3	0.5	1.5	-0.3	-0.1	-0.3	-0.9	-0.6	-0.2	0.9	-0.7	1.2
Medication: Paracetamol	0.6	0.9	1.9	0.6	1.2	0.9	-1.4	0.7	-0.0	0.8	0.7	1.4
Medication: Lisinopril	0.5	0.6	1.5	1.2	-1.0	0.7	0.6	0.2	1.1	0.4	0.8	0.1
Medication: Atorvastatin	0.3	0.4	1.1	0.6	0.4	0.5	-1.0	0.0	0.2	0.8	0.4	0.7
Illnesses of father: High blood pressure	0.3	0.3	2.0	-0.3	-0.5	-0.1	-1.4	-0.4	-0.1	-0.0	-0.3	0.2
Alcohol drinker status: Never	0.5	0.6	1.0	1.0	0.8	0.6	-0.2	0.6	0.6	1.0	0.8	0.9
Ever smoked	0.5	0.9	3.5	0.2	1.9	-0.3	-1.6	-0.8	0.4	0.7	-0.3	1.0
Basal metabolic rate	0.1	0.6	2.1	0.3	-0.4	-0.1	1.2	-0.6	-0.5	-0.9	-0.0	-1.4
Leg fat percentage (left)	0.5	1.8	4.7	2.2	1.0	1.0	-0.3	1.0	2.0	1.0	1.7	-0.1
Arm fat-free mass (left)	0.0	0.2	0.8	0.9	-0.4	0.2	0.4	-0.4	0.0	0.1	0.4	-0.6
Number of operations (self-reported)	0.1	0.2	0.5	0.6	0.4	0.4	-0.0	0.1	-0.0	-0.0	0.7	-0.6
Average weekly beer plus cider intake	0.7	1.1	5.7	-0.4	2.4	-0.5	-0.5	-1.1	0.2	-0.8	-0.5	-1.0
Irritability	0.6	1.1	2.6	-0.3	0.5	-1.0	0.7	-1.5	-1.6	-0.8	-1.1	-1.1
Risk taking	0.4	0.6	3.1	-0.1	0.9	0.4	-1.8	0.4	-0.6	-0.7	0.3	-0.2
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.0	-0.3	0.8	-0.9	-1.3	-1.4	-0.5	0.4	-0.8	-0.1
Fractured/broken bones in last 5 years	0.4	0.5	1.7	-0.9	0.3	-0.8	-0.5	-0.5	-1.3	-0.3	-0.5	-0.3
Age started oral contraceptive pill	0.4	0.5	1.6	0.1	-0.8	-0.6	0.6	-0.9	1.3	0.0	-0.5	-0.9
Diastolic blood pressure, automated reading	0.3	1.0	2.9	1.2	0.7	1.0	-0.7	0.3	0.6	1.7	0.5	1.4
Ever depressed for a whole week	0.2	0.3	1.1	0.3	-0.5	-0.5	-0.6	-1.1	0.4	0.3	-0.6	0.2
Unable to work because of sickness or disability	0.5	0.6	1.9	-0.2	1.4	-0.3	-1.3	-0.0	-0.5	0.8	-0.4	0.9
Commuting to job workplace: Cycle	1.2	1.5	7.9	-0.9	-2.8	-0.4	-0.8	-0.8	-1.3	-0.8	-0.7	-0.3
Myopia	0.4	0.6	1.5	-0.3	-1.1	0.9	0.6	1.0	-0.3	-1.2	0.7	-0.4
Vascular/heart problems diagnosed by doctor	0.3	0.8	2.1	0.3	0.1	1.1	0.6	0.8	-1.4	-1.3	0.8	-0.5
Cholesterol lowering medication	1.3	1.9	3.9	2.0	-0.6	1.7	-0.6	1.3	1.2	1.3	1.7	1.3
Medication: Omeprazole (e.g. Zanprol)	2.4	2.9	8.4	1.8	1.4	1.3	-1.7	0.8	0.7	2.9	0.6	2.6
Pain experienced in last month	1.1	1.8	3.1	-1.8	0.7	-1.5	0.1	-1.3	-1.0	-1.6	-1.4	-1.7
Supplements: Calcium	0.2	0.2	0.6	-0.6	0.4	-0.3	-0.0	-0.2	-0.3	-0.8	-0.4	-0.2
Basal cell carcinoma (self-reported)	0.1	0.1	0.5	0.1	-0.2	0.4	-0.6	0.7	0.1	-0.0	0.4	0.4
Heart attack/myocardial infarction (self-reported)	2.2	2.9	7.1	-1.5	1.1	-1.9	1.2	-1.8	-0.3	-2.1	-1.5	-2.7
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.9	0.3	0.5	0.4	1.0	0.5	1.4	0.5	0.4	0.3
Heart disease (siblings)	0.4	0.5	3.2	-0.1	0.4	-0.2	-1.8	-0.3	0.5	0.7	-0.1	0.7
Alcohol drinker status: Previous	2.5	2.8	4.4	-1.9	1.6	-2.1	1.9	-1.8	-0.3	-1.2	-1.9	-1.5
Pack years of smoking	0.5	0.7	2.1	-0.8	0.5	-1.2	-1.5	-0.8	0.1	-0.0	-1.0	-0.1
Impedance of whole body	0.9	4.7	7.8	2.1	-1.7	2.3	-2.1	2.5	0.9	2.4	2.3	2.8
Leg fat mass (left)	0.4	1.7	5.6	2.4	0.6	1.2	0.0	0.9	1.8	1.1	1.7	-0.2
Arm predicted mass (left)	0.0	0.2	0.5	0.6	-0.5	0.1	0.4	-0.4	-0.3	-0.1	0.2	-0.7