Hub : Genes

SLC18B1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adrenal Gland	0.1865	0.0719	8.6e-03	0.085	NA	0.003	NA	0.005	5.9e-04	NA	2.4e-01	NA	2.0e-01
2	GTEx	Cells EBV-transformed lymphocytes	0.4230	0.1170	5.9e-04	0.221	NA	0.262	NA	0.281	9.0e-08	NA	4.3e-09	NA	9.4e-10
3	GTEx	Cells Transformed fibroblasts	0.2110	0.0570	2.0e-04	0.180	NA	0.112	NA	0.177	1.8e-13	NA	1.0e-08	NA	3.1e-13
4	GTEx	Colon Transverse	0.1920	0.0760	6.6e-03	0.068	NA	0.023	NA	0.040	3.8e-04	NA	2.7e-02	NA	5.2e-03
5	GTEx	Prostate	0.3840	0.1200	5.1e-03	-0.009	NA	0.010	NA	0.002	6.1e-01	NA	1.7e-01	NA	2.9e-01
6	GTEx	Whole Blood	0.1110	0.0410	2.2e-03	0.047	NA	0.042	NA	0.041	3.6e-05	NA	9.3e-05	NA	1.0e-04
7	METSIM	Adipose	0.1571	0.0332	1.4e-11	0.121	0.088	0.114	0.110	0.111	1.0e-17	4.1e-13	1.1e-16	3.5e-16	2.8e-16
8	ROSMAP	Brain Pre-frontal Cortex	0.0773	0.0312	4.0e-03	0.017	0.001	0.005	0.009	0.013	2.3e-03	2.2e-01	6.8e-02	1.9e-02	6.7e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.4	0.6	1.8	0.9	-0.4	-0.5	-1.3	-0.1	-0.5	-0.5	-1.0
Bipolar Disorder or Schizophrenia	0.2	0.5	1.4	0.1	-0.8	-1.2	-0.5	0.9	-0.4	-0.9	0.3
Depressed Affect (Nagel 2018)	0.1	0.3	1.1	-0.0	0.2	1.0	0.3	0.1	0.5	0.9	-0.0
Depression (Nagel 2018)	0.3	0.4	0.9	0.7	-0.5	-0.5	-0.9	0.2	-0.5	-0.5	-1.0
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.1	0.4	1.0	1.4	-0.1	-0.5	0.1	1.1	-0.2
Neuroticism (Nagel 2018)	0.2	0.5	1.1	1.1	-0.6	0.1	-0.8	0.9	-0.2	0.4	-0.9
Schizophrenia (2018)	0.3	0.7	1.6	-0.6	-0.7	-1.1	0.5	1.2	-0.1	-0.8	1.0
Schizophrenia vs Biploar Disorder	0.2	0.3	0.9	0.5	-0.5	-0.7	-0.2	-0.9	-0.2	-0.4	-0.4
Worry (Nagel 2018)	0.1	0.3	0.8	0.9	-0.3	-0.0	-0.6	-0.4	-0.1	0.1	-0.9
Alzheimer’s Disease (in mother)	2.2	2.6	5.4	2.2	-1.1	-1.0	-2.2	-0.5	-1.3	-1.3	-2.3
Alzheimer’s Disease (in father)	0.1	0.1	0.5	0.1	0.7	0.2	0.1	-0.2	-0.1	0.7	0.1
Alzheimer’s Disease (including proxy)	0.4	0.6	1.9	1.4	-0.2	-0.3	-1.0	0.5	-0.7	-0.0	-1.1
Crohns Disease (2017)	1.0	2.3	4.1	1.9	-1.7	-0.8	-1.8	0.4	-1.6	-0.9	-2.0
Irritable Bowel Disease (IBD)	0.6	1.5	2.8	1.3	-1.7	-0.5	-1.4	1.1	-1.2	-1.0	-1.4
Ulcerative Colitis (UC)	0.1	0.2	0.7	0.0	-0.8	0.4	-0.3	0.9	-0.3	-0.4	-0.1
Major Depression (MDD)	0.3	0.4	1.7	0.5	-0.4	0.6	0.1	1.3	0.6	0.6	-0.1
Reaction Time	0.1	0.3	0.6	-0.7	0.4	0.6	0.6	-0.6	0.5	0.2	0.5
Verbal and Numeric Reasoning (VNR)	0.3	0.6	2.2	0.6	0.6	1.5	0.1	-0.0	0.6	1.3	-0.2
Breast Cancer	0.5	1.3	4.2	-0.8	0.5	1.3	0.9	2.1	1.2	0.8	0.8
Ovarian Cancer	0.7	1.0	2.2	1.0	-1.1	-1.5	-0.8	-0.3	-1.0	-0.9	-0.7
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.4	0.6	1.7	1.0	0.7	-0.1	-0.9	-0.7	-0.0	0.5	-1.3
Bipolar Disorder (2011)	0.6	0.6	3.2	-0.2	-0.1	-0.6	-0.3	1.8	-0.4	-1.0	0.3
Body Mass Index (BMI) (2010)	0.2	0.2	0.7	0.9	-0.3	-0.3	-0.4	0.0	-0.6	-0.3	-0.7
Coronary Artery Disease (CAD)	1.4	1.6	6.3	-0.9	1.2	1.1	1.0	2.5	1.2	0.9	0.5
Crohns Disease (2012)	1.7	2.7	3.7	1.5	-1.9	-1.6	-1.9	0.7	-1.8	-1.8	-1.7
Mean Putamen Volume	4.2	4.8	7.6	2.0	-2.8	-2.5	-2.1	-0.5	-2.6	-2.4	-1.8
Fasting Glucose	0.3	0.4	1.7	0.6	0.4	1.3	-0.3	0.6	-0.3	0.4	-0.2
HbA1C	0.1	0.1	0.9	-0.1	-0.3	-0.2	0.3	0.9	0.0	0.3	-0.1
HDL Cholesterol	0.0	0.0	0.2	-0.1	0.1	0.0	0.2	-0.1	-0.0	-0.3	0.4
LDL Cholesterol	0.8	1.3	5.3	1.3	-0.6	0.7	-0.9	2.3	-0.4	0.1	-1.3
Lupus	0.2	0.3	1.4	0.4	-0.6	-0.5	-0.1	1.2	-0.3	0.1	0.1
Neuroticism (2016)	0.2	0.3	1.9	-0.2	0.1	-0.1	0.2	1.4	0.5	0.1	0.1
Primary Biliary Cirrhosis	0.1	0.2	0.5	0.4	0.2	0.3	-0.5	-0.3	0.3	0.4	-0.7
Rheumatoid Arthritis	1.2	1.7	3.9	-1.9	0.9	0.7	1.8	0.0	1.1	0.6	2.0
Schizophrenia (2014)	0.3	0.7	3.3	-0.4	-0.7	-0.7	0.0	1.8	-0.1	-0.7	0.6
Triglycerides	2.1	3.5	9.0	1.9	-1.9	-1.1	-1.8	3.0	-1.6	-1.2	-1.8
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.8	0.2	-0.9	-1.0	-0.6	0.5	-1.1	-1.7	0.1
Ulcerative Colitis	0.7	1.0	4.1	0.1	-1.2	-0.6	-0.5	2.0	-0.7	-1.2	-0.1
Blood Eosinophil Count	0.0	0.4	0.9	-0.9	0.0	-0.4	0.5	0.5	0.6	-0.4	1.0
Blood Platelet Count	0.1	1.4	3.0	0.6	-1.0	-1.7	-1.1	-1.2	-1.2	-1.5	-0.7
Blood Red Count	0.0	0.3	0.9	-0.6	-0.4	-0.6	-0.1	1.0	-0.2	-0.8	0.5
Blood White Count	0.3	2.2	7.4	0.4	-0.8	-2.2	-0.9	-2.7	-1.3	-1.5	-0.3
Heel T-Score	9.2	72.9	96.2	7.5	-9.8	-9.2	-8.2	8.2	-9.7	-8.8	-6.3
BMI	0.4	2.1	4.3	0.8	-1.9	-2.1	-1.1	-1.1	-1.4	-1.8	-0.6
Height	0.3	6.2	38.2	-1.2	1.5	0.9	1.3	-6.2	1.2	1.3	1.5
Waist Hip Ratio (WHR)	3.5	15.8	27.7	3.2	-5.3	-4.5	-3.5	1.7	-4.7	-4.8	-2.9
Systolic Blood Pressure	0.6	3.0	4.4	1.4	-2.1	-1.0	-2.1	1.7	-2.0	-1.7	-1.7
Smoking Status	0.2	0.6	1.5	-0.9	0.3	-0.0	0.9	-1.2	0.2	0.0	1.1
Allergy or Eczema	1.2	3.2	5.6	-1.4	2.4	2.2	1.6	0.3	2.1	2.3	1.0
Cardiovascular Disease	3.3	10.9	16.3	3.3	-4.0	-3.1	-3.6	1.1	-3.6	-3.4	-3.4
Hypothyroidism (self reported)	3.1	7.1	9.5	-3.1	2.8	3.0	3.0	-0.4	2.5	2.8	2.8
Respiratory disease	2.4	5.2	7.7	1.8	-2.4	-2.6	-2.3	-2.0	-2.1	-2.8	-2.1
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.9	-0.7	0.4	0.2	0.8	1.0	0.6	0.1	0.7
Lung FEV1/FVC ratio	0.3	1.3	5.2	0.0	0.7	1.2	0.5	2.3	0.9	1.5	0.2
Lung FVC	0.1	0.3	0.9	-0.9	0.3	-0.2	0.2	-0.8	0.6	-0.4	0.2
Neuroticism	0.1	0.1	0.4	0.5	-0.7	0.0	-0.3	0.0	-0.4	-0.0	-0.4
Chronotype (morning person)	0.1	0.1	0.4	0.1	0.0	0.3	-0.1	-0.6	0.5	0.3	-0.4
Hair Pigment	0.1	1.6	4.0	-0.5	2.0	1.9	0.4	-0.4	1.1	1.7	0.6
Tanning	0.2	2.1	3.9	-1.8	1.2	1.0	1.8	-1.7	1.0	0.7	2.0
Hand grip strength (left)	0.3	0.8	1.7	0.6	-0.9	-1.3	-0.7	0.1	-1.3	-1.0	-0.3
Number of treatments/medications taken	0.4	0.8	2.8	-0.1	-1.0	-1.0	-0.3	1.7	-0.2	-1.2	-0.2
Average weekly spirits intake	0.3	0.4	0.8	0.4	-0.9	-0.8	-0.6	0.3	-0.6	-0.9	-0.3
Sensitivity / hurt feelings	0.2	0.4	0.9	0.1	0.7	0.6	0.3	0.6	0.8	1.0	-0.1
Frequency of depressed mood in last 2 weeks	0.9	1.2	2.6	0.6	-1.2	-1.2	-1.0	1.6	-0.9	-1.3	-0.7
Hearing difficulty/problems: Yes	0.1	0.2	0.8	0.3	-0.1	-0.2	-0.4	-0.9	-0.5	-0.3	-0.5
Relative age of first facial hair	0.4	0.8	1.7	1.3	-0.6	0.5	-1.2	-0.7	-0.9	0.0	-0.9
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	4.2	0.1	0.6	0.8	0.2	2.0	1.0	0.9	-0.3
Ever used hormone-replacement therapy (HRT)	1.2	1.6	4.5	0.5	-1.2	-2.1	-0.7	0.8	-1.5	-1.8	-0.5
Ever had hysterectomy (womb removed)	0.6	0.7	1.0	0.5	-0.9	-0.8	-1.0	-0.8	-0.5	-0.9	-0.9
Systolic blood pressure, automated reading	0.4	1.1	4.8	-1.4	-0.3	-0.2	0.7	2.2	-0.1	-0.4	1.2
Eye problems/disorders: Diabetes related eye disease	2.4	2.7	5.8	-0.9	1.7	1.6	1.2	-2.4	1.9	1.7	1.1
Angina	3.4	4.5	7.6	1.9	-2.3	-2.8	-2.1	0.4	-1.9	-2.7	-2.0
Medication for hormone replacement therapy	0.3	0.3	2.7	-0.1	0.0	0.1	0.1	1.6	0.1	0.2	0.2
Vitamin and mineral supplements	0.1	0.1	0.2	-0.4	0.2	0.4	0.5	-0.3	0.2	0.4	0.2
Supplements: Zinc	0.6	0.7	3.6	0.6	-0.2	-0.6	-0.7	1.9	0.2	-0.1	-0.6
Medication: Co-codamol	0.5	0.6	1.7	-0.6	1.1	0.9	0.5	0.1	1.3	0.5	0.4
Medication: Metformin	0.5	0.7	1.5	-1.2	-0.2	-0.5	0.9	0.1	1.1	-0.5	1.1
Diabetes (father)	0.7	0.8	2.9	-0.6	-0.8	-0.6	0.8	1.7	0.1	-0.5	1.1
Diabetes (mother)	0.3	0.4	1.0	0.0	0.8	1.0	0.1	0.3	0.7	0.9	0.0
Severe depression (siblings)	0.7	0.7	2.4	-0.6	0.8	0.8	0.3	1.6	1.1	0.7	0.4
Pack years adult smoking proportion	0.4	0.6	1.2	1.0	0.1	0.1	-1.0	1.1	-0.7	-0.2	-1.1
Impedance of leg (right)	2.2	10.5	14.2	-2.8	3.3	3.6	3.5	1.6	3.6	3.8	3.0
Leg fat-free mass (left)	1.2	6.6	9.6	1.6	-2.8	-3.1	-2.2	-2.9	-2.8	-3.1	-1.5
Trunk fat percentage	0.2	0.6	1.3	-1.1	-0.7	-0.8	0.8	-0.5	0.3	-0.6	1.2
Hand grip strength (right)	1.2	3.1	5.9	1.3	-1.8	-2.4	-1.8	-0.5	-2.1	-2.1	-1.3
Townsend deprivation index at recruitment	0.5	0.7	1.2	0.8	-1.0	-0.8	-1.0	-0.2	-0.7	-1.1	-0.7
Current tobacco smoking	0.2	0.4	2.4	-0.3	0.6	-0.4	0.0	-1.6	0.1	-0.2	0.4
Average weekly fortified wine intake	0.8	1.0	3.7	-0.6	0.7	0.8	0.7	-1.9	1.1	0.9	0.2
Maternal smoking around birth	0.2	0.2	1.0	1.0	0.0	0.2	-0.3	-0.3	0.0	0.7	-0.6
Fed-up feelings	0.4	0.7	1.5	1.2	-1.0	-0.1	-0.9	0.8	-0.5	-0.2	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	1.9	3.3	1.6	-1.4	-1.1	-1.8	-0.7	-1.4	-1.0	-1.8
Relative age voice broke	0.1	0.2	0.4	0.6	-0.3	0.5	-0.6	-0.1	-0.3	0.1	-0.4
Taking other prescription medications	1.7	2.6	3.5	-1.9	1.7	1.2	1.8	1.5	1.8	1.3	1.6
Age when periods started (menarche)	1.1	2.7	12.1	-0.9	1.0	1.4	1.0	3.5	1.0	1.5	1.1
Bilateral oophorectomy (both ovaries removed)	1.5	1.7	3.4	0.5	-1.4	-1.9	-1.1	-0.9	-1.6	-1.7	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	5.4	12.3	18.3	2.8	-3.9	-3.8	-3.1	4.1	-4.3	-3.5	-2.1
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.6	0.4	0.2	0.8	-0.4	0.3	0.1	0.4	-0.8
Qualifications: CSEs or equivalent	0.7	0.9	1.6	0.3	-1.0	-1.2	-0.9	-1.1	-0.4	-1.3	-0.9
Serious illness, injury or assault to yourself	3.7	4.5	6.3	2.2	-2.1	-2.2	-2.5	1.4	-2.0	-2.2	-2.1
High blood pressure	3.4	9.4	15.6	3.1	-4.0	-3.2	-3.2	1.5	-2.8	-3.2	-3.0
Hayfever, allergic rhinitis or eczema	0.6	1.3	2.9	-0.8	1.7	1.4	0.6	0.6	1.4	1.4	0.2
Multivitamins +/- minerals	0.3	0.3	1.3	0.7	0.4	0.0	-0.6	-1.1	-0.0	-0.0	-0.6
Stomach or abdominal pain in last month	0.4	0.4	1.5	0.6	-0.3	-0.2	-0.9	-0.3	-1.2	-0.6	-0.5
Supplements: Glucosamine	0.5	0.6	3.0	-0.6	0.4	-0.1	0.6	-1.7	0.7	0.3	0.6
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.4	-0.3	0.3	0.7	0.2	0.2	0.2	0.2	0.0
Medication: Atenolol	0.0	0.1	0.3	-0.3	-0.2	0.0	-0.0	0.1	0.5	-0.2	-0.0
Medication: Levothyroxine sodium	2.2	3.7	7.8	-1.2	2.1	2.4	1.6	1.5	2.0	2.8	0.9
Sitting height	0.9	6.2	24.0	1.6	-1.8	-2.3	-2.0	-4.9	-2.2	-1.9	-1.6
Chronic bronchitis/emphysema (father)	2.2	2.5	4.7	1.4	-1.7	-1.8	-1.7	0.3	-2.2	-1.6	-1.4
High blood pressure (mother)	2.0	2.7	5.1	1.1	-2.1	-2.0	-1.6	-1.3	-1.2	-2.3	-1.2
Body mass index (BMI)	0.6	2.5	5.4	0.5	-2.1	-2.3	-1.1	-0.2	-1.5	-2.3	-0.6
Impedance of leg (left)	1.8	8.6	13.2	-2.4	3.2	3.3	3.0	1.2	3.4	3.6	2.5
Leg predicted mass (left)	1.2	6.3	9.4	1.5	-2.8	-3.0	-2.1	-2.9	-2.7	-3.1	-1.4
Trunk fat mass	0.2	1.0	1.8	-0.8	-1.1	-1.4	0.5	-1.3	-0.3	-1.2	0.9
Waist circumference	1.0	3.5	7.7	0.9	-2.8	-2.8	-1.3	-1.0	-1.7	-2.4	-0.9
Number of incorrect matches in round	0.3	0.4	1.6	0.6	-0.9	-0.6	-0.2	1.3	-0.2	-0.3	-0.3
Past tobacco smoking	0.1	0.3	0.7	-0.3	0.8	0.6	-0.2	-0.2	0.6	0.6	-0.0
Alcohol usually taken with meals	1.4	2.2	4.4	-0.8	1.8	2.1	1.2	1.0	1.6	1.9	0.8
Nervous feelings	0.5	0.9	2.2	-0.2	1.3	0.9	0.4	-0.5	1.5	1.4	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.0	1.0	-0.9	-0.4	-0.8	0.4	-0.5	-0.4	-0.6
Hearing difficulty/problems with background noise	1.3	2.1	3.1	1.6	-1.4	-1.2	-1.5	1.2	-1.8	-1.2	-1.6
Hair/balding pattern: Pattern 2	1.0	1.3	8.1	-0.7	-0.4	-0.6	-0.0	2.9	-0.6	-0.8	0.5
Had menopause	2.2	2.7	4.1	-1.8	2.0	1.5	2.0	-0.9	1.8	1.5	1.5
Had other major operations	1.1	1.3	2.2	-1.0	1.5	1.2	1.1	-1.1	1.1	1.0	1.0
Forced vital capacity (FVC)	0.5	1.8	12.4	-0.0	-0.3	-1.0	-0.3	-3.5	-0.7	-0.8	0.0
Heel bone mineral density (BMD) T-score, automated (right)	9.2	21.2	30.7	3.5	-5.5	-5.2	-4.0	4.4	-5.5	-5.0	-2.9
Ever unenthusiastic/disinterested for a whole week	0.0	0.1	0.1	-0.2	-0.1	0.4	0.3	-0.2	-0.1	0.3	0.2
Qualifications: None of the above	0.8	1.8	6.8	-1.6	0.2	-0.1	1.2	2.6	1.2	-0.3	1.3
Financial difficulties in last 2 years	0.1	0.1	0.3	-0.0	0.1	-0.2	0.5	-0.2	0.2	0.4	0.5
Mouth/teeth dental problems	0.7	1.0	2.0	0.9	-1.2	-0.8	-1.0	0.8	-1.4	-1.0	-0.7
Heart attack	3.0	3.8	7.0	1.4	-2.6	-2.4	-1.7	1.4	-1.7	-2.4	-1.5
Allergy	0.1	0.2	0.6	-0.2	-0.0	0.3	0.6	0.3	-0.0	0.3	0.8
Pain all over the body in last month	0.3	0.3	1.3	0.9	0.1	0.3	-0.4	0.3	0.4	0.2	-1.1
Diabetes (self-reported)	0.1	0.1	0.5	-0.4	0.2	0.1	0.5	-0.2	0.7	0.1	0.4
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	2.1	-0.9	1.4	1.4	0.6	0.8	0.9	1.2	0.7
Medication: Ramipril	1.7	2.2	9.4	-0.0	-1.7	-1.8	-0.3	3.1	-0.5	-1.4	0.3
Medication: Simvastatin	0.6	0.9	2.1	-1.1	-0.9	-0.9	0.8	1.5	-0.0	-0.8	0.9
Fluid intelligence score	0.2	0.5	1.6	-0.2	0.5	1.3	0.5	0.3	0.8	0.9	0.4
Illnesses of siblings	2.7	3.8	5.4	-2.1	2.3	2.1	1.9	-1.6	1.4	1.9	2.1
Neuroticism score	0.2	0.3	1.0	1.0	-0.5	-0.1	-0.7	0.4	-0.3	0.1	-0.9
Weight	0.6	2.8	5.4	0.4	-2.0	-2.3	-1.0	-2.2	-1.5	-2.2	-0.4
Impedance of arm (right)	1.5	7.0	13.1	-1.4	3.1	3.6	2.5	-0.0	3.1	3.6	1.7
Arm fat percentage (right)	0.2	0.6	1.6	0.2	-1.3	-1.2	-0.4	-0.1	-0.6	-1.2	-0.1
Trunk fat-free mass	0.6	3.6	6.7	1.2	-1.8	-2.2	-1.7	-2.6	-2.0	-2.0	-1.1
Hip circumference	0.2	1.0	5.8	-0.5	-0.4	-0.9	0.2	-2.4	0.4	-0.5	0.5
Time employed in main current job	0.2	0.3	1.5	0.3	-0.2	-0.1	-0.1	-1.2	0.6	0.2	-0.2
Alcohol intake versus 10 years previously	1.0	1.6	3.0	-1.2	-1.2	-1.6	0.3	1.4	-0.9	-1.7	1.0
Father’s age at death	5.0	6.6	9.8	-2.3	3.0	3.1	2.6	-1.4	2.4	3.0	2.2
Worrier / anxious feelings	0.0	0.0	0.1	0.1	-0.0	-0.4	-0.1	0.1	0.2	-0.3	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	1.5	0.2	-0.8	-1.0	-0.8	1.2	-0.8	-0.9	-0.4
Falls in the last year	0.2	0.3	1.4	-0.6	0.4	0.2	0.4	-1.2	0.4	-0.2	0.3
Hair/balding pattern: Pattern 3	0.8	1.3	2.2	-1.5	1.0	0.4	1.5	-1.2	0.7	0.5	1.5
Number of live births	0.1	0.2	0.5	0.5	-0.7	-0.3	-0.3	0.3	0.0	-0.2	-0.6
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	5.2	0.3	0.0	-0.5	-0.3	-2.3	-0.4	-0.2	-0.2
Pulse rate	2.1	3.5	6.5	-2.5	1.4	0.9	2.3	-2.4	0.9	0.9	2.5
Happiness	0.1	0.1	0.4	-0.1	-0.6	-0.5	0.1	0.2	0.2	-0.2	0.2
Noisy workplace	0.7	0.9	3.3	0.3	0.6	1.3	-0.0	1.8	0.4	1.1	-0.3
Qualifications: A levels/AS levels or equivalent	0.3	0.6	4.3	0.3	0.6	-0.2	-0.2	-2.1	-0.2	0.3	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.7	0.6	-0.7	-0.0	-0.6	0.2	-0.8	-0.5	-0.3
Mouth/teeth dental problems: Dentures	0.1	0.2	0.6	0.1	0.3	0.3	0.3	-0.8	0.2	0.5	0.1
Asthma	2.1	4.2	6.1	1.7	-2.1	-2.2	-2.4	-1.3	-2.0	-2.5	-2.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.1	-0.1	0.3	0.3	0.8	1.0	0.6	1.0	0.3
Medication: Cholesterol lowering	0.4	0.7	2.9	0.2	-1.1	-0.4	-0.2	1.7	-0.4	-1.0	-0.2
Depression (self-reported)	2.0	2.4	4.3	1.5	-2.1	-2.0	-1.4	0.2	-1.7	-1.7	-1.2
Medication: Lansoprazole	0.1	0.1	0.5	0.2	-0.6	-0.2	0.3	0.7	-0.0	-0.2	0.1
Prospective memory result	1.8	2.2	3.9	1.2	-1.3	-2.0	-1.6	-0.0	-1.3	-2.0	-1.5
Lung cancer (father)	3.4	4.0	5.9	2.0	-2.1	-1.6	-2.4	1.2	-2.4	-1.9	-2.1
Illnesses of mother	0.6	0.7	1.8	0.1	0.8	1.2	0.6	1.0	0.4	1.4	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	1.0	0.4	0.2	-0.0	-0.4	-1.0	-0.1	0.1	-0.4
Pulse wave Arterial Stiffness index	1.7	1.9	2.9	1.3	-1.6	-1.5	-1.4	0.4	-1.7	-1.7	-1.2
Impedance of arm (left)	1.2	5.3	9.4	-1.4	2.5	2.9	2.3	0.1	2.9	3.1	1.6
Arm fat mass (right)	0.5	2.0	4.3	0.3	-1.9	-2.0	-0.9	-0.9	-1.2	-2.1	-0.4
Trunk predicted mass	0.6	3.3	6.4	1.1	-1.8	-2.1	-1.6	-2.5	-1.9	-1.9	-1.1
Standing height	0.3	2.7	20.3	-0.5	0.4	0.1	0.5	-4.5	0.2	0.4	0.8
Length of working week for main job	0.6	0.7	3.0	0.3	0.6	1.7	-0.1	-0.4	0.6	1.1	-0.5
Exposure to tobacco smoke at home	0.2	0.2	1.0	-0.1	-0.2	0.1	0.2	-1.0	-0.0	0.6	0.0
Breastfed as a baby	0.1	0.1	0.3	0.5	-0.2	-0.2	-0.3	0.4	-0.2	-0.0	-0.5
Tense / ‘highly strung’	0.2	0.3	0.5	-0.6	0.5	0.5	0.7	0.3	0.7	0.7	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	3.3	1.6	-0.9	-0.4	-1.5	0.9	-0.5	0.0	-1.8
Hair/balding pattern: Pattern 4	1.1	2.6	6.1	1.4	-2.5	-1.6	-1.3	1.2	-1.9	-1.6	-1.0
Birth weight of first child	0.9	1.6	4.9	-0.6	1.5	2.2	0.8	0.5	0.8	1.8	0.5
Peak expiratory flow (PEF)	0.7	1.6	2.7	0.7	-0.9	-1.6	-1.3	-1.3	-1.4	-1.5	-1.0
Pulse wave reflection index	2.3	2.9	4.7	2.2	-1.6	-1.5	-2.1	0.8	-1.5	-1.3	-2.1
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.3	-0.1	-0.1	-0.1	0.3	-0.6	-0.2	0.1	0.2
Loud music exposure frequency	1.3	1.5	2.0	-1.0	1.4	1.4	1.3	0.6	1.3	1.4	1.1
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	4.1	1.0	-0.5	-0.6	-0.9	-2.0	-0.6	-0.5	-0.7
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	2.3	-1.5	0.3	0.2	1.0	0.2	0.7	0.2	1.2
Blood clot in the leg (DVT)	2.7	3.5	5.7	2.2	-2.4	-2.1	-1.8	-0.5	-2.0	-1.8	-1.6
Medication: Paracetamol	0.3	0.5	1.3	-0.3	0.5	0.7	0.6	1.2	0.9	0.9	0.5
Headache pain in last month	0.1	0.2	0.8	-0.1	0.3	0.9	-0.1	0.2	0.3	0.5	0.2
Medication for cholesterol, blood pressure or diabetes	1.2	2.0	5.7	-1.1	1.7	0.9	1.1	-2.4	0.8	1.5	1.2
Glaucoma (self-reported)	0.2	0.2	0.8	-0.9	0.2	-0.1	0.4	-0.4	-0.1	-0.3	0.7
Gout (self-reported)	0.8	1.1	3.7	-1.5	-0.3	-0.7	1.4	-0.6	-0.1	-0.5	1.9
Hypothyroidism/myxoedema (self-reported)	1.8	3.5	5.0	-1.9	2.1	2.1	2.1	-0.2	1.9	2.2	1.7
Medication: Amlodipine	3.8	5.4	9.7	1.7	-3.1	-3.1	-2.1	-0.0	-2.2	-3.0	-1.6
Medication: Ventolin 100micrograms inhaler	0.6	0.7	2.4	-1.0	-0.5	-0.9	0.2	-1.6	-0.1	-0.9	0.6
Birth weight	0.4	0.8	1.7	1.2	-0.4	-0.2	-1.1	-1.3	-0.7	-0.0	-1.1
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.8	-1.3	-0.1	-0.2	0.8	-0.1	0.0	-0.8	1.1
High blood pressure (siblings)	1.9	2.8	4.0	1.9	-1.9	-1.6	-1.6	1.0	-1.5	-1.6	-2.0
Forced vital capacity (FVC), Best measure	0.1	0.5	3.6	-0.1	0.6	0.1	-0.0	-1.9	0.2	0.2	0.1
Body fat percentage	0.1	0.6	1.2	-1.0	-0.7	-0.8	0.7	-0.3	0.2	-0.7	1.1
Leg fat percentage (right)	0.2	0.8	2.2	-1.4	-0.1	-0.4	1.2	0.6	0.6	-0.2	1.5
Arm fat-free mass (right)	1.3	6.4	12.0	1.0	-2.9	-3.5	-1.9	-2.6	-2.8	-3.4	-1.0
Exposure to tobacco smoke outside home	0.8	1.0	2.6	0.2	-1.6	-1.6	-0.6	0.5	-0.6	-1.4	-0.2
Comparative body size at age 10	0.1	0.2	0.9	0.3	-0.4	-0.4	-0.2	-1.0	-0.4	-0.7	-0.1
Number of full brothers	0.1	0.1	0.5	0.3	-0.1	-0.1	-0.3	0.7	-0.1	-0.0	-0.1
Worry too long after embarrassment	0.3	0.6	0.9	0.9	-0.7	-0.5	-0.7	0.9	-0.9	-0.4	-0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.1	0.4	0.5	0.7	-0.3	-0.5	0.4	1.0	-0.6
Wheeze or whistling in the chest in last year	2.4	4.3	6.5	1.7	-1.8	-2.3	-2.4	-1.3	-2.4	-2.6	-1.8
Number of children fathered	1.3	1.5	2.2	1.4	-1.5	-0.9	-1.1	-1.0	-1.4	-1.1	-1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.6	1.3	-1.1	-0.3	-0.4	0.9	-0.9	-0.2	-0.7	1.1
Age at first live birth	0.5	0.8	2.0	-1.1	0.6	1.4	0.9	0.1	0.1	0.6	1.3
Pulse wave peak to peak time	2.0	2.4	3.6	-1.4	1.8	1.7	1.5	-0.5	1.9	1.9	1.3
Health satisfaction	0.2	0.2	0.7	-0.5	-0.3	-0.0	0.7	-0.4	-0.0	0.2	0.8
Shortness of breath walking on level ground	0.1	0.1	0.3	0.2	-0.0	0.2	-0.2	0.5	0.3	0.1	-0.4
Qualifications: College or University degree	0.1	0.4	1.5	0.6	0.5	0.7	-0.3	0.4	0.1	1.2	-0.4
Eye problems/disorders: None of the above	0.1	0.1	0.1	-0.3	-0.1	0.1	0.3	-0.1	-0.3	0.1	0.4
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.4	-0.1	1.1	1.1	0.5	1.0	0.9	1.2	0.1
Emphysema/chronic bronchitis	0.4	0.4	0.9	0.4	-0.6	-0.7	-0.9	-0.2	-0.5	-0.9	-0.7
Medication for pain relief, constipation, heartburn	0.5	0.8	5.1	-0.3	0.7	0.5	0.4	-2.3	-0.2	0.2	0.5
Neck or shoulder pain in last month	1.1	1.6	2.3	1.4	-1.4	-1.1	-1.5	0.3	-0.9	-1.4	-1.5
Medication: Blood pressure	1.8	3.3	5.8	1.5	-2.4	-1.7	-1.8	1.8	-1.3	-2.0	-1.7
Angina (self-reported)	4.0	5.3	9.6	2.0	-2.6	-3.1	-2.2	0.2	-2.1	-3.0	-2.0
Migraine (self-reported)	2.2	2.7	5.0	-1.3	1.9	1.9	1.7	0.4	1.6	2.2	1.6
Medication: Ibuprofen	1.0	1.2	2.7	-0.9	0.9	0.5	1.6	0.8	1.2	1.3	1.3
Medication: Allopurinol	0.6	0.8	2.7	-1.3	0.2	-0.1	1.2	-0.4	0.3	0.2	1.6
Medication: Omeprazole	0.5	0.5	2.5	0.5	-0.2	-0.0	-0.8	1.6	-0.2	-0.3	-0.9
Medication: Seretide 50 evohaler	0.4	0.4	2.1	0.6	-0.1	0.0	-0.5	-1.4	-0.5	-0.2	-0.7
Mean time to correctly identify matches	1.5	2.9	4.0	-1.8	1.8	1.9	2.0	0.0	2.0	1.7	1.6
Heart disease (mother)	0.7	0.8	4.0	0.2	0.7	0.1	0.3	2.0	1.2	0.8	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.3	0.5	-0.4	0.1	-0.1	0.6	-0.1	0.5	-0.3
Whole body fat mass	0.2	1.0	2.1	-0.8	-1.2	-1.4	0.3	-1.1	-0.4	-1.3	0.8
Leg fat mass (right)	0.2	1.0	2.3	-0.7	-1.2	-1.5	0.2	-0.7	-0.6	-1.5	0.7
Arm predicted mass (right)	1.3	6.9	13.0	1.3	-3.0	-3.6	-2.1	-2.4	-2.9	-3.3	-1.3
Pulse rate, automated reading	1.2	3.8	8.2	-2.6	1.7	1.0	1.9	-2.9	0.9	0.5	2.7
Alcohol intake frequency.	0.4	1.0	2.5	0.4	-1.3	-0.9	-0.9	1.6	-0.8	-1.1	-0.6
Comparative height size at age 10	0.2	1.2	9.4	0.1	-0.3	-0.2	0.3	-3.1	-0.2	0.1	0.1
Number of full sisters	3.4	4.2	7.3	1.8	-2.1	-2.0	-2.4	-0.6	-2.1	-2.7	-2.1
Suffer from ‘nerves’	0.1	0.2	0.5	0.6	-0.0	0.3	-0.7	-0.4	-0.3	0.3	-0.7
Overall health rating	0.5	1.1	2.7	0.3	-1.3	-1.6	-0.7	0.7	-0.8	-1.6	-0.6
Chest pain or discomfort	0.6	0.8	1.9	0.3	-1.2	-1.4	-0.8	-0.4	-0.4	-1.4	-0.4
Had major operations	0.3	0.4	0.8	-0.4	0.4	0.9	0.4	0.8	0.9	0.7	0.3
Age at last live birth	0.2	0.3	1.3	0.1	0.3	1.1	-0.3	0.5	-0.3	0.3	-0.3
Family relationship satisfaction	0.3	0.3	2.0	-0.3	-0.5	-0.3	-0.0	1.4	0.0	-0.2	0.1
Leg pain on walking	0.9	1.1	3.1	-1.8	0.4	0.0	1.3	0.4	0.8	-0.5	1.8
Qualifications: NVQ or HND or HNC or equivalent	3.6	4.3	7.5	2.7	-1.8	-1.9	-2.5	-0.6	-2.2	-1.4	-2.7
Commuting to job workplace: Car/motor vehicle	0.6	0.6	1.8	0.3	-1.2	-0.9	-0.4	0.5	-1.3	-0.7	-0.5
Illness, injury, bereavement, stress in last 2 years	1.6	2.0	2.9	-1.4	1.4	1.6	1.5	-0.5	1.5	1.7	1.3
Medication: Aspirin	2.5	3.3	5.4	1.7	-2.3	-1.9	-2.1	0.9	-1.5	-2.0	-1.8
Supplements: Vitamin C	0.9	1.0	1.8	-1.1	0.9	0.2	1.4	-0.3	1.3	0.9	1.3
Knee pain experienced in last month	0.7	1.1	2.3	0.6	-1.5	-1.2	-0.8	0.1	-1.2	-1.5	-0.9
Hypertension (Self-reported)	3.4	9.4	15.9	3.1	-4.0	-3.2	-3.2	1.2	-2.9	-3.3	-3.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	2.3	1.5	-1.2	-1.1	-1.1	1.4	-1.0	-1.0	-1.4
Illnesses of father: Heart disease	0.1	0.1	0.4	-0.2	0.1	-0.1	-0.2	-0.6	0.2	-0.6	0.0
Illnesses of siblings: Diabetes	1.6	1.9	6.0	1.2	-1.2	-1.4	-1.2	2.4	-1.1	-1.0	-0.9
Smoking status: Previous	0.1	0.2	0.7	-0.2	-0.5	0.0	0.6	0.8	-0.2	-0.1	0.3
Forced expiratory volume in 1-second (FEV1), predicted	1.1	2.4	7.3	1.4	-1.2	-1.0	-1.4	-2.7	-1.8	-1.1	-1.0
Whole body fat-free mass	1.0	5.5	8.5	1.4	-2.4	-2.8	-2.0	-2.9	-2.5	-2.7	-1.4
Leg fat-free mass (right)	1.4	7.5	10.3	1.9	-2.9	-3.2	-2.5	-3.0	-3.0	-3.1	-1.9
Arm fat percentage (left)	0.2	0.8	2.1	0.1	-1.4	-1.4	-0.3	-0.0	-0.5	-1.4	-0.0
Average weekly red wine intake	0.2	0.3	1.1	1.0	-0.7	-0.1	-0.5	0.2	-0.1	-0.2	-0.8
Handedness (chirality/laterality): Left-handed	0.7	0.8	1.7	-1.1	0.8	0.5	1.2	-0.8	0.7	0.5	1.3
Mood swings	0.3	0.6	1.4	1.2	-0.2	0.3	-0.7	1.0	-0.1	0.8	-1.0
Loneliness, isolation	1.0	1.4	3.8	-0.1	-2.0	-1.7	-0.3	0.0	-0.8	-1.8	0.2
Long-standing illness, disability or infirmity	0.3	0.5	2.3	0.6	-0.4	-0.5	-0.3	1.5	0.5	-0.3	-0.5
Ever had bowel cancer screening	1.2	1.3	2.5	-1.3	0.7	0.8	1.6	0.2	1.5	1.2	1.4
Diabetes diagnosed by doctor	0.2	0.3	0.8	-0.7	0.0	0.2	0.6	0.3	0.9	-0.1	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.9	0.4	-0.4	-0.4	-0.2	1.4	-0.3	-0.2	-0.3
Friendships satisfaction	0.6	0.7	4.4	-0.6	-0.3	0.3	0.4	2.1	-0.3	0.3	0.7
Qualifications: nursing, teaching	0.1	0.1	0.2	0.4	0.1	0.5	-0.2	-0.5	-0.3	0.3	-0.2
Commuting to job workplace: Walk	0.7	0.8	3.3	0.1	-0.2	-0.8	-0.4	-1.8	-0.8	-1.1	-0.0
Eye problems/disorders: Cataract	0.7	0.8	2.0	0.6	-0.9	-1.2	-0.8	0.7	-0.7	-1.4	-0.6
Mouth/teeth dental problems: Mouth ulcers	2.0	3.2	6.1	-1.3	2.3	2.2	1.5	0.4	2.5	2.1	1.2
Medication for cholesterol	1.3	2.0	5.9	-0.4	2.0	2.4	0.7	-1.1	0.9	1.8	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	3.3	-1.3	0.5	0.5	0.8	1.8	0.5	0.4	0.9
Back pain experienced in last month	0.9	1.4	2.5	1.1	-1.6	-1.3	-1.2	0.3	-1.0	-1.4	-1.0
Mineral and other dietary supplements	0.1	0.1	0.4	0.1	-0.2	0.3	-0.1	0.4	-0.6	-0.0	0.1
Breast cancer (self-reported)	0.2	0.2	0.6	-0.5	0.1	-0.4	0.4	-0.6	-0.7	-0.4	0.4
Asthma (self-reported)	1.8	3.7	5.2	1.5	-2.0	-2.2	-2.1	-1.4	-1.9	-2.3	-1.8
Osteoporosis (self-reported)	0.5	0.6	1.6	-0.4	-0.7	-0.9	-0.3	-1.3	-0.5	-1.3	0.1
Osteoarthritis (self-reported)	0.3	0.4	1.1	-1.0	-0.4	-0.5	0.5	-0.5	0.4	-0.6	0.7
Medication: Aspirin	2.7	3.5	5.4	1.9	-2.3	-1.7	-2.3	0.7	-1.7	-1.9	-2.0
Medication: Gliclazide	2.3	2.6	4.4	-1.9	1.6	1.1	2.1	0.4	2.1	1.2	1.9
Illnesses of father: None of the above (group 1)	0.8	1.0	2.2	1.1	-0.8	-0.4	-1.5	-0.4	-1.1	-0.4	-1.5
Smoking status: Current	0.2	0.4	2.7	0.1	0.4	-0.4	-0.2	-1.6	-0.1	-0.1	-0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.1	-0.7	0.9	0.6	0.8	1.0	0.9	0.4	0.6
Whole body water mass	1.1	6.0	8.6	1.5	-2.6	-2.9	-2.2	-2.9	-2.7	-2.9	-1.5
Leg predicted mass (right)	1.4	7.7	10.3	1.9	-2.9	-3.2	-2.6	-3.2	-3.0	-3.1	-1.9
Arm fat mass (left)	0.6	2.3	5.3	0.3	-2.2	-2.3	-0.9	-0.7	-1.4	-2.3	-0.4
Number of self-reported non-cancer illnesses	0.5	0.8	2.0	-0.2	-1.4	-1.0	-0.2	1.4	-0.4	-1.2	-0.1
Average weekly champagne plus white wine intake	2.4	3.2	5.3	-1.3	2.2	2.2	1.9	0.3	1.8	2.3	1.5
Miserableness	0.0	0.1	0.1	0.2	-0.2	0.1	0.1	0.4	0.2	0.3	0.1
Guilty feelings	0.3	0.5	3.3	-0.3	0.2	-0.1	0.1	1.8	0.4	0.2	0.1
Wears glasses or contact lenses	0.3	0.3	0.8	0.2	0.8	0.6	0.2	0.6	0.4	0.9	-0.3
Ever taken oral contraceptive pill	2.3	2.6	6.6	1.5	-2.6	-1.7	-1.1	0.8	-1.9	-1.8	-0.8
Hearing aid user	0.8	1.0	2.7	-0.7	1.6	0.8	0.6	-1.3	0.6	1.2	0.4
Mother’s age at death	0.4	0.5	1.0	-0.3	1.0	0.6	0.7	-0.7	0.8	1.0	0.7
Financial situation satisfaction	0.6	0.7	1.7	-0.9	0.6	1.3	0.9	0.7	0.5	1.1	0.8
Tinnitus: Yes, now most or all of the time	1.1	1.3	2.7	-1.0	1.6	1.2	1.0	-0.2	1.2	1.2	1.0
Commuting to job workplace: Public transport	0.1	0.2	0.6	-0.1	0.7	-0.0	-0.0	-0.8	0.6	0.1	0.0
Eye problems/disorders: Glaucoma	0.1	0.1	0.3	-0.5	0.4	0.1	0.1	-0.6	0.1	-0.1	0.2
Medication: Blood pressure	2.4	4.6	9.9	1.7	-2.9	-3.1	-2.0	0.7	-1.6	-2.6	-1.5
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.4	-0.5	0.6	0.4	0.5	-0.6	0.7	0.1	0.5
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.3	-0.1	-0.2	-0.3	0.2	-0.1	0.5	-0.2	0.2
High cholesterol (Self-reported)	0.4	0.6	4.4	-0.5	-0.0	0.1	0.4	2.1	0.4	-0.1	0.4
Medication: Bendroflumethiazide	2.1	3.2	7.3	0.9	-2.2	-2.6	-1.3	0.5	-1.9	-2.7	-0.6
Medication: Paracetamol	0.3	0.5	0.8	-0.6	0.4	0.6	0.9	0.6	0.8	0.7	0.9
Medication: Lisinopril	0.7	1.0	1.5	0.9	-1.2	-0.2	-1.1	-0.8	-1.2	-0.9	-1.1
Medication: Atorvastatin	0.4	0.5	1.3	1.2	-0.5	0.1	-0.6	1.1	0.1	0.1	-0.9
Illnesses of father: High blood pressure	1.0	1.3	2.9	-1.5	0.7	-0.0	1.5	-0.1	1.7	0.2	1.5
Alcohol drinker status: Never	0.1	0.1	0.6	0.2	0.1	-0.1	-0.0	0.8	-0.4	0.1	0.0
Ever smoked	0.1	0.2	0.6	0.0	0.4	0.2	0.4	-0.7	0.4	0.3	0.2
Basal metabolic rate	1.0	5.6	8.5	1.4	-2.6	-2.9	-2.0	-2.8	-2.5	-2.8	-1.3
Leg fat percentage (left)	0.1	0.5	1.2	-1.0	-0.4	-0.7	0.7	0.2	0.4	-0.4	1.1
Arm fat-free mass (left)	1.2	5.9	9.9	1.1	-2.7	-3.1	-2.1	-2.5	-2.7	-3.1	-1.2
Number of operations (self-reported)	3.1	4.5	8.5	-2.9	1.6	1.6	2.7	0.2	2.5	1.2	2.8
Average weekly beer plus cider intake	0.1	0.1	0.4	-0.5	0.2	-0.1	0.1	0.6	0.1	-0.2	0.2
Irritability	0.3	0.4	1.1	0.9	-0.6	-0.5	-0.8	-0.2	-0.6	-0.2	-1.0
Risk taking	0.0	0.1	0.2	-0.1	0.4	0.2	0.0	-0.1	0.2	0.4	0.2
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.6	-0.1	0.4	0.5	0.3	0.8	0.6	0.4	-0.2
Fractured/broken bones in last 5 years	0.4	0.5	3.0	0.3	0.0	-0.2	-0.5	-1.7	0.0	-0.0	-0.6
Age started oral contraceptive pill	0.1	0.1	0.2	-0.3	0.3	0.0	0.4	-0.2	0.1	0.4	0.4
Diastolic blood pressure, automated reading	0.2	0.6	1.5	-1.2	-0.7	-0.2	0.5	0.6	-0.7	-0.9	1.1
Ever depressed for a whole week	0.4	0.5	0.8	-0.8	0.7	0.6	0.9	-0.9	0.3	0.3	0.9
Unable to work because of sickness or disability	1.0	1.4	3.3	0.6	-1.5	-1.5	-1.1	-0.7	-0.6	-1.8	-0.9
Commuting to job workplace: Cycle	2.3	2.8	4.3	2.1	-1.5	-1.6	-2.0	0.6	-1.5	-1.6	-1.9
Myopia	0.8	1.1	2.4	-0.9	1.2	0.4	1.3	-0.1	1.6	1.1	1.0
Vascular/heart problems diagnosed by doctor	3.6	9.9	17.1	-3.0	4.1	3.4	3.1	-2.2	2.8	3.2	3.0
Cholesterol lowering medication	0.5	0.8	2.3	0.1	-1.0	-1.5	-0.2	1.3	-0.6	-1.0	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	3.0	0.9	-0.4	0.0	-1.0	1.7	-0.8	-0.4	-1.1
Pain experienced in last month	1.4	2.4	4.5	-1.8	1.5	1.2	2.0	0.2	1.1	1.6	2.1
Supplements: Calcium	0.6	0.7	2.3	0.1	-0.4	-1.5	-0.7	-0.8	-0.7	-1.0	-0.6
Basal cell carcinoma (self-reported)	1.0	1.2	2.4	1.3	-1.0	-0.8	-1.4	0.3	-1.1	-0.7	-1.6
Heart attack/myocardial infarction (self-reported)	3.0	3.8	6.7	1.4	-2.6	-2.2	-1.8	1.6	-1.7	-2.4	-1.6
Deep venous thrombosis (DVT) (self-reported)	3.7	4.8	8.3	2.4	-2.9	-2.6	-2.0	-0.6	-2.4	-2.2	-1.7
Heart disease (siblings)	0.2	0.2	0.8	0.2	-0.6	-0.5	-0.2	0.9	0.3	-0.6	-0.4
Alcohol drinker status: Previous	1.8	2.0	3.3	1.3	-1.8	-0.8	-1.8	1.6	-0.8	-1.2	-1.7
Pack years of smoking	0.5	0.7	3.0	0.7	0.7	0.7	-0.7	1.7	-0.2	0.3	-0.9
Impedance of whole body	1.4	7.4	11.0	-2.2	3.0	3.1	2.9	0.5	3.2	3.3	2.4
Leg fat mass (left)	0.3	1.2	3.2	-0.4	-1.4	-1.8	-0.1	-1.0	-0.8	-1.7	0.5
Arm predicted mass (left)	0.9	4.7	8.2	0.9	-2.4	-2.9	-1.8	-2.4	-2.4	-2.8	-0.9