TWAS hub - SLC1A1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2470	0.0450	7.3e-09	0.091	0.108	0.185	0.204	0.170	3.5e-11	4.4e-13	5.8e-22	2.5e-24	3.7e-20
2	GTEx	Lung	0.1445	0.0474	2.7e-03	0.123	NA	0.109	NA	0.117	1.2e-09	NA	1.1e-08	NA	3.0e-09
3	ROSMAP	Brain Pre-frontal Cortex	0.1322	0.0427	2.0e-03	0.005	0.011	0.010	0.018	0.012	7.4e-02	1.3e-02	1.5e-02	1.9e-03	8.8e-03
4	TCGA	Bladder Urothelial Carcinoma	0.1180	0.0410	4.5e-04	0.033	0.041	0.046	NA	0.042	8.2e-04	2.1e-04	8.6e-05	NA	1.7e-04
5	TCGA	Breast Invasive Carcinoma	0.0494	0.0190	9.5e-05	0.019	0.019	0.025	NA	0.018	5.6e-05	7.4e-05	5.7e-06	NA	8.5e-05
6	TCGA	Colon Adenocarcinoma	0.3170	0.0940	1.2e-05	0.176	0.076	0.150	NA	0.174	2.1e-10	3.6e-05	5.3e-09	NA	2.5e-10
7	TCGA	Glioblastoma Multiforme	0.4560	0.1320	8.8e-03	0.019	-0.008	0.016	NA	0.047	8.7e-02	6.4e-01	1.0e-01	NA	1.5e-02
8	TCGA	Lung Adenocarcinoma	0.1004	0.0350	1.3e-04	0.100	0.030	0.062	NA	0.086	1.1e-11	1.8e-04	9.3e-08	NA	2.8e-10
9	TCGA	Lung Squamous Cell Carcinoma	0.1601	0.0430	1.8e-07	0.076	0.081	0.078	NA	0.077	6.0e-09	1.6e-09	3.1e-09	NA	4.5e-09
10	TCGA	Ovarian Serous Cystadenocarcinoma	0.2610	0.0820	8.9e-05	0.112	0.064	0.091	NA	0.106	5.2e-08	4.0e-05	9.3e-07	NA	1.2e-07
11	TCGA	Prostate Adenocarcinoma	0.1901	0.0528	5.0e-07	0.127	0.061	0.126	NA	0.147	3.2e-13	5.3e-07	4.3e-13	NA	3.8e-15
12	TCGA	Thyroid Carcinoma	0.0600	0.0290	3.6e-03	0.045	0.020	0.017	NA	0.015	3.2e-05	4.5e-03	7.2e-03	NA	1.3e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Illnesses of father: High blood pressure	4.5	5.5	13.5	-1.2	0.3	-2.1	3.0	2.8	2.2	2.0	2.0	2.8	2.4	2.0	3.7
Medication: Lansoprazole	3.6	4.2	8.8	-1.1	-0.5	0.7	3.0	2.7	2.4	1.8	2.4	1.5	2.4	2.6	1.6
Diabetes (father)	3.4	4.2	9.8	-1.2	0.2	0.1	2.4	1.1	2.7	3.1	2.8	1.3	2.8	2.4	1.3
Heel bone mineral density (BMD) T-score, automated (left)	3.3	7.4	16.8	-1.6	0.3	-1.1	2.5	2.1	3.7	4.1	3.8	2.4	3.8	2.9	1.0
Illnesses of father: None of the above (group 1)	3.3	4.0	14.0	0.6	0.9	0.6	-3.0	-1.3	-1.8	-1.4	-2.0	-1.3	-2.4	-2.3	-3.7
Had major operations	3.1	3.6	7.6	0.1	0.9	0.1	-2.2	-2.8	-2.4	-2.5	-2.2	-1.5	-2.2	-1.5	-2.0
Heel bone mineral density (BMD) T-score, automated (right)	2.5	5.6	11.7	-1.4	0.0	-1.4	2.4	1.4	3.1	3.1	3.2	2.0	3.4	2.5	1.9
Cholesterol lowering medication	2.5	3.7	9.2	0.8	0.6	0.6	3.0	0.1	2.1	2.3	2.4	2.0	2.6	2.1	1.6
Commuting to job workplace: Walk	2.4	2.5	6.0	2.3	0.2	1.3	-1.5	-0.5	-1.8	-1.2	-2.0	-1.2	-1.9	-2.5	-1.1
Supplements: Vitamin C	2.3	2.7	4.3	0.4	-0.4	1.7	2.0	-1.0	2.0	1.4	2.1	2.1	1.8	2.0	1.5
Average weekly fortified wine intake	2.1	2.5	8.0	-2.8	1.3	-1.4	0.9	0.5	1.6	1.7	1.8	1.5	1.5	1.9	-0.2
High blood pressure (mother)	2.1	2.9	4.5	-2.0	1.0	-1.5	1.0	2.0	2.1	1.8	2.1	1.7	2.0	1.9	0.5
Falls in the last year	2.1	2.9	11.0	1.2	2.1	1.7	0.5	0.7	1.7	1.8	1.8	3.3	1.6	1.0	1.1
Birth weight of first child	2.1	3.7	9.2	0.5	-1.3	2.0	-1.5	-1.1	-1.9	-2.6	-1.9	-2.4	-2.3	-1.3	-3.0
Chest pain or discomfort	1.9	2.8	7.3	1.0	0.1	0.3	1.8	0.7	2.0	2.1	1.9	1.5	2.3	1.3	2.7
Medication: Blood pressure	1.9	3.6	7.3	-0.1	-1.4	0.0	2.7	1.8	2.3	1.9	2.4	1.8	2.1	2.2	1.9
Alzheimer’s Disease (in father)	1.8	2.0	8.9	-0.8	0.5	-1.0	1.2	2.5	0.8	0.4	0.9	0.9	1.3	0.9	3.0
Medication: Simvastatin	1.8	2.6	8.1	0.2	-0.0	0.1	1.8	0.9	1.5	2.8	1.9	0.7	2.6	1.0	2.2
Taking other prescription medications	1.7	2.6	5.2	0.7	0.7	0.8	2.0	0.8	1.8	2.1	1.9	1.9	2.3	1.3	1.8
Number of children fathered	1.7	2.0	6.7	0.9	-0.8	1.9	0.0	-1.7	-1.1	-2.6	-1.7	-0.6	-2.0	-0.5	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	5.3	0.3	0.2	-0.1	-1.6	-0.9	-1.8	-1.9	-2.3	-0.9	-2.3	-2.0	-0.0
Time employed in main current job	1.6	1.8	3.8	0.5	0.7	-0.7	1.0	0.8	1.7	1.9	1.8	1.5	1.7	1.3	1.4
Illnesses of mother	1.6	2.0	5.5	1.3	-0.6	1.4	-0.9	-2.3	-1.3	-0.5	-1.2	-2.3	-0.8	-1.3	-1.5
Health satisfaction	1.6	2.1	5.5	0.2	1.6	1.1	1.2	1.5	1.3	0.7	1.3	2.1	1.4	1.1	2.3
Shortness of breath walking on level ground	1.6	1.9	5.6	1.2	0.7	0.7	1.2	1.3	1.5	1.4	1.4	1.7	1.4	1.0	2.4
Medication: Seretide 50 evohaler	1.6	1.8	3.5	0.4	-1.4	0.5	-1.1	-1.6	-1.9	-1.3	-1.7	-1.3	-1.7	-1.8	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	3.7	0.7	0.8	1.6	0.5	0.9	1.6	1.4	1.9	1.2	1.7	1.7	-0.5
Medication: Bendroflumethiazide	1.6	2.4	7.4	0.4	0.1	-0.8	1.8	1.3	1.3	0.9	1.6	2.7	1.6	1.7	2.2
Stomach or abdominal pain in last month	1.5	1.9	5.2	-1.2	2.0	-0.5	1.2	0.9	1.3	1.3	1.4	2.3	1.4	1.3	0.6
Medication for cholesterol	1.5	2.3	5.9	-0.2	0.8	-0.1	-2.4	0.3	-1.7	-1.5	-1.8	-1.5	-1.7	-1.8	-2.1
Peak expiratory flow (PEF)	1.4	3.2	12.8	-2.8	-2.1	-3.6	-0.9	0.7	-0.7	0.0	-0.7	-2.4	-0.7	-0.7	-2.0
Hearing aid user	1.4	1.6	13.2	1.0	-0.0	3.6	0.5	-1.8	0.0	-0.2	-0.2	-1.0	0.2	0.1	-0.2
Major Depression (MDD)	1.3	1.5	3.4	-0.1	1.1	-0.2	0.8	1.0	1.8	0.0	1.8	1.7	1.8	1.1	1.3
Cardiovascular Disease	1.3	4.2	9.4	-1.9	-0.4	-1.8	1.3	2.3	2.5	3.1	2.7	0.7	2.7	1.9	1.5
Type 2 Diabetes (T2D) (2018)	1.3	2.4	7.0	-0.2	0.7	0.1	1.6	1.4	1.8	2.6	2.2	1.2	2.3	1.5	0.7
Medication: Metformin	1.3	1.8	4.0	-0.1	1.1	0.3	1.4	1.4	0.9	2.0	1.6	1.8	1.9	0.7	1.2
Current tobacco smoking	1.3	2.1	4.9	-1.0	-1.6	-1.3	-1.5	-0.4	-1.8	-0.4	-1.5	-2.2	-1.3	-1.8	-1.4
Financial difficulties in last 2 years	1.3	1.7	3.9	-1.1	-2.0	-0.7	-1.0	-0.5	-1.5	-0.9	-1.4	-1.6	-1.4	-1.6	-1.4
Loud music exposure frequency	1.3	1.5	4.9	1.0	0.1	0.4	-0.7	-2.0	-1.2	-1.4	-1.3	-2.2	-0.7	-0.9	-0.7
Ever had bowel cancer screening	1.3	1.5	3.0	-0.8	-0.5	1.1	-0.9	-1.3	-1.7	-1.1	-1.6	0.2	-1.7	-1.7	-0.7
Miserableness	1.3	2.2	8.8	-2.7	2.1	-3.0	-0.5	1.5	0.1	1.1	0.0	1.4	-0.2	-0.6	-0.1
Pain type(s) experienced in last month: Hip pain	1.3	1.7	3.6	1.2	1.2	0.4	-1.1	-1.6	-1.7	-1.9	-1.5	-0.4	-1.4	-1.3	-1.1
Medication: Lisinopril	1.3	1.7	4.5	0.2	-1.5	0.6	-1.3	-1.5	-1.5	-1.4	-1.3	-2.1	-1.1	-1.2	-1.1
Basal cell carcinoma (self-reported)	1.3	1.5	4.3	1.1	-1.3	0.4	0.7	-0.2	1.6	0.6	1.6	-0.9	1.5	2.1	-1.4
Schizophrenia (2014)	1.2	2.7	5.7	-1.6	-0.8	-1.1	-1.9	-0.8	-2.0	-1.9	-2.1	-2.4	-1.6	-1.9	-0.2
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	3.3	-1.6	1.0	-1.8	0.0	-1.6	-1.1	-1.0	-1.1	1.0	-1.0	-1.1	1.1
High cholesterol (Self-reported)	1.2	2.2	5.4	0.1	-0.9	1.0	1.0	0.3	2.0	2.3	2.2	-0.6	2.2	1.9	-0.3
Medication: Paracetamol	1.2	1.9	5.6	-1.3	1.1	-1.6	0.7	1.0	1.5	0.1	1.7	1.8	1.4	2.4	-0.2
Irritability	1.2	2.1	5.6	-1.8	0.6	-1.5	1.8	0.7	1.0	1.0	1.3	2.1	0.9	1.1	2.4
Pain experienced in last month	1.2	2.0	4.7	1.0	-2.0	1.7	-0.5	-0.2	-1.0	-2.0	-1.6	-2.2	-1.7	-0.9	-0.6
Heart disease (siblings)	1.2	1.4	6.9	1.3	-0.6	2.6	0.7	-0.2	1.3	0.2	1.3	-0.0	1.0	1.7	0.0
Neuroticism (2016)	1.1	1.5	4.0	-1.1	0.1	-1.2	-1.1	0.2	-1.7	-0.8	-1.7	-0.8	-1.8	-2.0	-0.3
Ulcerative Colitis	1.1	1.5	4.7	0.6	-0.6	-1.1	-1.2	-1.2	-1.6	-2.2	-1.4	-1.0	-1.3	-1.2	0.2
Number of treatments/medications taken	1.1	2.0	4.5	0.6	-0.7	0.3	1.8	1.2	1.4	1.7	1.7	1.3	2.1	1.1	2.0
Medication for hormone replacement therapy	1.1	1.3	5.5	0.5	0.9	0.1	-1.0	-2.4	-1.1	-1.4	-1.3	-0.1	-1.4	-0.8	0.3
Hearing difficulty/problems with background noise	1.1	1.7	5.8	0.2	-0.3	1.2	-1.1	-0.9	-1.4	-2.4	-1.7	0.3	-1.9	-1.5	0.8
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	5.3	0.8	-0.5	0.7	-1.5	-0.8	-1.3	-0.3	-1.1	-0.4	-1.2	-1.4	-2.3
Pain all over the body in last month	1.1	1.2	4.8	-0.7	0.1	0.3	-1.0	-2.2	-1.4	-1.2	-1.2	-0.5	-1.4	-1.1	-0.0
Breastfed as a baby	1.1	1.4	2.9	1.6	-1.7	0.9	-0.7	-1.1	-1.3	-0.5	-1.2	-1.5	-0.9	-1.4	-0.1
Neck or shoulder pain in last month	1.1	1.6	5.1	-0.2	0.1	-2.3	0.0	1.1	1.3	1.7	1.3	2.0	1.4	0.3	0.5
Leg fat mass (right)	1.1	4.1	7.6	1.0	1.0	-0.2	2.8	2.7	2.0	2.3	2.2	1.9	2.7	1.6	2.3
Knee pain experienced in last month	1.1	1.7	7.5	-0.0	2.7	-1.8	-0.2	0.8	0.5	1.6	1.1	1.8	1.3	0.3	-0.2
Osteoarthritis (self-reported)	1.1	1.4	7.4	-1.2	1.1	-0.2	0.5	0.7	0.7	0.3	0.6	2.1	0.6	0.3	2.7
Schizophrenia vs Biploar Disorder	1.0	1.4	2.1	1.2	-1.2	0.4	-1.2	-1.5	-1.3	-1.0	-1.3	-1.4	-1.2	-1.2	-0.7
Reaction Time	1.0	2.0	8.0	-0.9	2.8	-0.3	0.6	1.7	1.0	1.6	1.2	2.1	1.5	0.3	-0.2
Diabetes (mother)	1.0	1.3	7.3	-1.3	0.9	-0.3	0.7	-0.1	0.9	0.5	1.0	2.7	0.6	0.8	1.5
Pack years adult smoking proportion	1.0	1.6	4.8	1.9	-1.2	0.2	-1.1	-0.8	-1.1	0.6	-0.6	-2.1	-0.4	-1.1	-2.2
Leg fat-free mass (left)	1.0	5.5	9.1	-2.8	-0.7	-2.8	2.2	2.8	2.1	3.0	2.2	1.1	2.8	1.6	2.7
Leg predicted mass (left)	1.0	5.3	8.9	-2.8	-0.6	-2.8	2.2	2.8	2.0	3.0	2.1	1.1	2.7	1.5	2.6
Hair/balding pattern: Pattern 2	1.0	1.2	5.5	2.3	0.1	0.1	1.3	-0.3	0.2	-0.1	0.3	1.7	0.5	0.4	2.0
Qualifications: None of the above	1.0	2.1	6.5	2.4	1.6	2.6	0.2	1.0	0.8	1.5	1.0	1.6	0.6	0.6	-1.4
Alcohol intake versus 10 years previously	1.0	1.5	3.0	0.9	0.1	1.5	1.3	0.8	1.2	1.4	1.5	1.0	1.7	1.1	1.4
Depression (self-reported)	1.0	1.2	6.0	2.1	-0.5	2.5	0.1	1.5	0.7	0.8	0.4	-0.0	0.5	-0.1	0.2
Lung cancer (father)	1.0	1.2	4.8	-0.6	1.5	-0.0	-0.5	-0.5	-1.4	-2.2	-1.1	-1.3	-1.0	-0.4	-0.3
Comparative body size at age 10	1.0	2.8	7.6	0.9	-0.0	0.4	2.2	1.3	1.9	2.6	2.3	1.1	2.8	1.4	0.1
Mean time to correctly identify matches	1.0	2.0	6.6	-0.5	2.6	0.4	0.9	1.7	1.3	1.1	1.3	2.1	1.5	0.6	0.8
Leg pain on walking	1.0	1.2	4.0	1.7	-0.5	1.3	1.0	0.1	-1.2	-2.0	-1.0	0.5	-0.5	-0.6	1.3
Guilty feelings	1.0	1.6	4.9	-0.5	1.7	-2.2	0.6	1.0	0.3	1.7	0.9	2.0	0.8	0.1	-1.0
Ever taken oral contraceptive pill	1.0	1.2	2.5	-1.0	0.8	-0.1	-1.2	-0.1	-1.4	-0.6	-1.4	-1.2	-1.3	-1.6	-0.8
Alcohol drinker status: Previous	1.0	1.1	3.7	-0.2	-0.4	1.0	-0.5	-0.3	-1.4	-1.9	-1.6	-0.5	-1.5	-0.9	0.2
Pack years of smoking	1.0	1.5	5.7	2.4	-0.9	0.7	-0.8	-0.9	-1.0	0.3	-0.6	-2.1	-0.3	-0.9	-1.8
Schizophrenia (2018)	0.9	1.9	4.5	0.0	-0.7	0.3	-1.7	-0.8	-1.7	-2.1	-1.9	-1.2	-1.9	-1.6	-0.1
Blood Platelet Count	0.9	10.0	38.3	-5.6	-1.1	2.2	-6.2	-1.0	-1.9	0.5	-2.3	-3.2	-2.6	-3.9	-1.6
Vitamin and mineral supplements	0.9	1.3	4.0	-1.7	1.3	-2.0	-1.2	1.7	-0.6	-0.3	-0.7	-0.9	-0.7	-0.6	-0.1
Multivitamins +/- minerals	0.9	1.1	3.2	1.2	-1.1	0.9	1.8	-1.2	0.6	0.6	1.0	0.9	1.1	1.0	0.1
Supplements: Glucosamine	0.9	1.2	5.9	-0.7	-0.7	-2.4	-0.6	-0.0	-1.1	-1.6	-0.9	0.2	-1.2	-0.7	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	4.0	-1.2	-1.0	-1.2	-1.1	-0.1	-1.4	-0.5	-1.5	-0.6	-1.5	-2.0	-0.7
Neuroticism score	0.9	1.8	8.6	-2.9	1.0	-2.6	0.1	1.4	0.1	1.5	0.4	0.9	0.0	-0.4	-0.2
Noisy workplace	0.9	1.1	4.0	0.6	-1.4	2.0	0.6	0.6	1.1	0.4	0.8	-1.3	0.8	1.3	0.1
Blood clot in the leg (DVT)	0.9	1.2	3.1	-0.6	-0.4	0.4	-0.4	0.0	-1.8	-1.6	-1.7	0.4	-1.7	-1.3	-0.3
Gout (self-reported)	0.9	1.2	2.3	-0.7	-0.7	1.3	0.6	1.0	1.4	1.5	1.3	0.8	1.4	0.5	1.4
Leg fat percentage (right)	0.9	3.4	6.2	2.5	1.5	0.7	2.4	1.8	1.7	1.6	2.0	1.7	2.4	1.5	1.4
Pulse wave peak to peak time	0.9	1.0	4.0	-0.3	1.6	-1.2	0.7	1.0	0.7	1.0	0.8	2.0	0.6	0.4	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.9	4.2	-1.8	-1.6	-1.7	1.4	1.0	1.5	2.0	1.4	0.9	1.3	0.7	0.7
Loneliness, isolation	0.9	1.2	6.5	0.7	-2.5	0.2	0.0	-0.2	-1.1	-1.2	-1.2	-0.9	-1.3	-1.0	-0.2
Smoking status: Current	0.9	1.4	3.3	-0.9	-1.5	-0.9	-1.1	-0.4	-1.4	-0.3	-1.2	-1.8	-1.1	-1.4	-1.2
Wears glasses or contact lenses	0.9	1.1	2.4	0.5	-1.6	0.4	-0.1	-1.3	-1.4	-1.5	-1.0	-1.3	-0.8	-0.4	-0.3
Age started oral contraceptive pill	0.9	1.1	5.2	0.6	-0.2	1.2	2.3	-0.3	0.7	-0.2	0.8	1.5	0.5	1.3	0.9
Commuting to job workplace: Cycle	0.9	1.0	8.1	-2.8	-1.1	-1.3	-0.3	0.8	0.1	0.7	0.2	0.2	-0.0	-0.3	0.4
Leg fat mass (left)	0.9	3.5	7.2	1.1	0.8	-0.2	2.7	2.5	1.7	2.0	1.9	1.6	2.5	1.4	2.3
Blood White Count	0.8	5.9	15.1	-0.4	-1.0	-0.7	-3.2	-1.0	-3.3	-1.7	-3.2	-3.1	-2.8	-3.9	-0.8
Heel T-Score	0.8	6.4	12.7	-2.0	-1.2	-0.8	2.8	1.2	3.2	3.2	3.4	0.9	3.6	3.1	2.3
Allergy or Eczema	0.8	2.1	3.5	-0.9	-1.3	-1.0	-1.5	-0.8	-1.9	-1.3	-1.5	-1.8	-1.6	-1.7	-1.6
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	6.7	-0.1	1.0	-0.5	0.5	0.9	0.1	-0.4	-0.0	0.9	0.5	-0.2	2.6
Medication: Atenolol	0.8	1.0	2.4	-0.3	-0.5	-1.1	0.7	0.3	1.2	1.3	1.2	0.3	1.4	0.9	1.6
Alcohol usually taken with meals	0.8	1.3	3.1	-0.0	0.1	-0.4	1.0	0.2	1.4	1.5	1.6	1.8	1.3	1.5	0.2
Nervous feelings	0.8	1.5	3.6	-1.0	-0.6	-1.9	-1.6	-0.8	-1.0	0.1	-1.0	-0.9	-1.2	-1.4	-1.8
Heart attack	0.8	1.0	4.7	0.7	-2.2	0.4	0.7	-1.0	-0.3	0.5	-0.0	-0.6	0.3	-0.0	2.1
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	3.3	-0.4	-0.6	-1.1	1.6	1.3	0.2	0.1	0.7	1.8	0.6	0.4	1.7
Pulse rate	0.8	1.3	2.8	1.3	-0.1	1.5	-0.1	-0.1	-1.7	-1.3	-1.4	-0.4	-0.8	-1.5	1.5
Qualifications: A levels/AS levels or equivalent	0.8	1.7	4.9	-0.1	-0.6	-1.4	-1.4	-1.7	-1.3	-0.6	-1.6	-0.7	-1.8	-2.2	-0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.6	21.2	-2.6	-1.1	-4.6	0.1	1.2	0.4	0.4	0.1	-0.1	0.0	0.5	-0.1
Exposure to tobacco smoke at home	0.8	0.9	3.6	-0.8	1.0	0.2	0.4	0.3	0.4	1.7	0.6	1.0	0.9	-0.1	1.9
Medication: Paracetamol	0.8	1.3	3.4	-1.8	1.8	-1.8	-0.4	0.9	0.4	-0.7	0.6	1.3	0.3	1.2	-1.0
High blood pressure (siblings)	0.8	1.2	6.6	-0.3	1.2	-1.2	0.6	0.0	0.8	-0.1	0.9	2.6	0.5	0.9	1.3
Arm fat-free mass (right)	0.8	4.1	11.1	-2.6	-0.4	-3.3	1.8	1.9	1.7	2.5	1.9	0.8	2.5	1.5	1.8
Angina (self-reported)	0.8	1.0	4.7	0.4	-0.7	-0.2	1.7	-0.2	0.6	1.1	0.7	0.6	1.2	0.7	2.2
Medication: Omeprazole	0.8	0.9	4.2	2.0	-0.9	1.8	-0.0	-0.5	-0.4	-0.2	-0.3	-1.4	-0.1	-0.3	0.3
Arm predicted mass (right)	0.8	4.1	8.6	-2.6	-0.5	-2.9	1.9	1.9	1.8	2.5	2.0	0.7	2.6	1.5	1.7
Pulse rate, automated reading	0.8	2.6	6.5	1.1	0.9	2.5	-1.3	-1.3	-2.3	-1.7	-2.0	-0.3	-1.6	-2.1	-0.3
Whole body fat-free mass	0.8	4.5	11.8	-3.1	-0.8	-3.4	1.8	2.2	1.4	2.6	1.7	0.5	2.4	1.1	2.3
Leg fat-free mass (right)	0.8	4.4	8.5	-2.9	-0.8	-2.7	2.1	2.5	1.6	2.5	1.7	0.7	2.3	1.3	2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	13.3	-1.6	-0.7	-3.6	-0.5	0.6	-0.9	-0.8	-0.8	-0.1	-0.8	-0.5	0.0
Whole body water mass	0.8	4.7	11.2	-3.0	-0.7	-3.3	2.0	2.2	1.5	2.7	1.8	0.7	2.5	1.2	2.3
Leg predicted mass (right)	0.8	4.3	8.9	-3.0	-0.7	-2.7	2.0	2.5	1.6	2.5	1.7	0.7	2.2	1.2	2.4
Arm fat-free mass (left)	0.8	4.1	8.5	-2.4	-0.3	-2.9	2.0	1.9	1.5	2.7	1.9	0.9	2.6	1.3	2.2
Fractured/broken bones in last 5 years	0.8	1.0	4.9	-1.2	2.0	-2.2	-0.3	1.0	-0.6	0.5	-0.0	-0.0	0.1	-0.3	-0.4
Arm predicted mass (left)	0.8	4.0	9.7	-2.4	0.2	-3.1	1.9	1.9	1.4	2.5	1.8	0.9	2.6	1.2	2.2
Bipolar Disorder (2018)	0.7	1.0	4.4	-1.4	1.8	-2.1	0.1	1.4	-0.3	0.0	-0.0	-0.1	0.5	-0.7	0.1
Sensitivity / hurt feelings	0.7	1.2	4.0	-2.0	-0.0	-1.8	0.9	0.3	0.9	1.2	1.2	0.6	1.0	0.9	0.1
Townsend deprivation index at recruitment	0.7	0.9	8.5	1.2	0.3	2.9	0.1	-0.1	-0.7	-0.4	-0.2	-0.3	-0.1	-0.2	-0.3
Hayfever, allergic rhinitis or eczema	0.7	1.6	3.0	-1.7	-1.2	-1.7	-1.1	-0.9	-1.4	-0.4	-1.2	-1.1	-1.2	-1.7	-0.8
Waist circumference	0.7	2.5	4.7	0.9	0.9	0.5	2.1	2.2	1.3	1.9	1.5	1.1	2.1	0.9	2.1
Trunk fat-free mass	0.7	4.0	14.0	-3.0	-0.9	-3.7	1.7	1.9	1.0	2.4	1.4	0.2	2.2	0.8	1.9
Happiness	0.7	0.8	2.0	0.9	1.2	0.4	-1.0	0.1	-1.1	-0.8	-1.0	0.8	-1.1	-1.4	-0.0
Pulse wave Arterial Stiffness index	0.7	0.8	3.4	0.2	-1.6	1.1	-0.5	-0.9	-0.5	-0.8	-0.5	-1.8	-0.3	-0.2	-0.6
Trunk predicted mass	0.7	4.2	14.3	-3.2	-0.8	-3.8	1.7	1.9	1.1	2.5	1.5	0.3	2.3	0.9	1.9
Exposure to tobacco smoke outside home	0.7	0.9	3.0	0.1	-1.0	0.2	1.7	0.2	1.0	1.1	0.9	-0.1	1.4	0.9	1.1
Number of full brothers	0.7	0.9	1.8	1.1	-1.2	-0.5	0.9	0.3	1.0	1.3	1.3	0.3	1.1	1.2	-0.3
Eye problems/disorders: None of the above	0.7	0.9	2.0	-0.2	-0.4	-0.4	-0.9	-1.2	-0.9	-1.2	-1.0	-0.6	-1.3	-0.6	-1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	1.8	1.0	0.9	0.4	-0.9	-1.3	-1.1	-1.1	-1.1	-0.7	-1.1	-0.7	-0.5
Comparative height size at age 10	0.7	4.0	9.8	-1.0	-1.8	-0.4	1.6	1.4	2.8	3.1	2.7	-0.1	2.8	2.4	0.4
Medication: Aspirin	0.7	1.0	3.3	-0.4	-1.7	-1.2	-0.1	-1.2	-1.1	-0.2	-0.7	-1.8	-0.2	-0.6	0.0
Mood swings	0.7	1.2	5.8	-1.7	1.1	-2.4	0.1	-0.7	-0.4	0.7	-0.1	1.2	0.2	-0.7	1.1
Long-standing illness, disability or infirmity	0.7	1.1	6.4	2.5	-1.0	0.8	0.9	-1.4	0.3	0.7	0.3	0.2	0.9	-0.3	0.7
Qualifications: nursing, teaching	0.7	1.0	4.2	-0.3	-1.1	-0.5	1.4	0.8	0.8	0.5	0.9	0.9	1.0	0.7	2.0
Basal metabolic rate	0.7	4.1	8.2	-2.5	-0.5	-2.9	2.0	2.3	1.5	2.7	1.8	0.7	2.5	1.1	2.3
Leg fat percentage (left)	0.7	2.5	6.4	2.5	1.3	0.8	2.3	1.6	1.2	1.1	1.5	1.2	2.0	1.2	1.4
Risk taking	0.7	1.1	3.3	0.5	1.8	-1.1	0.7	1.1	1.0	0.9	1.0	1.3	1.0	0.8	0.8
Ever depressed for a whole week	0.7	0.8	2.6	0.8	0.4	-0.3	-1.6	-0.3	-0.9	0.1	-0.6	-1.4	-0.4	-1.1	-1.3
Vascular/heart problems diagnosed by doctor	0.7	1.8	3.8	0.0	0.6	0.2	-1.2	-1.6	-1.4	-1.8	-1.5	-1.3	-1.8	-1.0	-2.0
Heart attack/myocardial infarction (self-reported)	0.7	0.9	5.2	0.2	-2.3	0.1	0.7	-0.9	-0.3	0.2	-0.1	-0.8	0.2	0.1	1.9
Bipolar Disorder or Schizophrenia	0.6	1.4	3.4	-0.9	0.6	-1.0	-1.4	0.2	-1.6	-1.1	-1.7	-0.9	-1.3	-1.8	-0.0
Alzheimer’s Disease (including proxy)	0.6	0.9	2.8	-0.1	-0.4	-0.3	1.1	1.1	0.6	1.0	0.9	0.1	1.5	0.7	1.7
Crohns Disease (2017)	0.6	1.2	9.1	0.3	3.0	0.2	-0.2	-0.7	-0.6	-1.7	-0.7	0.9	-0.5	-0.2	0.4
Ovarian Cancer	0.6	0.8	3.0	-1.2	0.1	-0.1	1.1	1.7	1.0	0.4	0.9	0.9	0.7	1.0	0.4
Age at First Birth	0.6	0.9	2.3	-1.4	-0.4	-0.9	-1.2	-0.6	-0.7	-0.7	-1.0	-1.5	-1.0	-0.6	-0.5
Coronary Artery Disease (CAD)	0.6	0.7	3.3	-1.8	0.0	-1.8	-0.7	0.6	0.0	-0.3	-0.2	0.3	-0.4	-0.1	1.1
Fasting Glucose	0.6	0.8	2.0	1.0	-0.6	-0.4	0.6	1.3	1.0	0.2	1.1	0.6	1.4	1.0	0.5
Lupus	0.6	0.9	2.3	-0.5	0.2	-1.2	0.7	1.4	0.8	1.4	1.1	1.5	1.0	0.3	0.3
Rheumatoid Arthritis	0.6	0.8	3.5	-0.5	-0.7	-1.2	0.9	-0.2	-0.6	-0.7	-0.4	1.5	-0.4	-0.3	1.9
Triglycerides	0.6	1.0	2.6	0.7	0.5	1.6	1.4	0.1	1.1	0.4	1.1	0.8	1.0	1.4	-0.1
Hearing difficulty/problems: Yes	0.6	0.9	2.1	0.0	0.2	-0.4	-0.9	-0.3	-1.4	-1.2	-1.5	-0.1	-1.4	-1.4	0.1
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	3.0	0.2	-1.3	0.1	-0.2	-1.7	-0.8	0.6	-0.4	-1.3	0.4	-1.0	-0.9
Ever had hysterectomy (womb removed)	0.6	0.7	1.1	-1.0	0.1	-0.9	0.8	0.6	0.7	0.6	0.9	0.9	1.0	1.1	0.7
Angina	0.6	0.7	4.0	0.4	-0.7	-0.2	1.4	-0.4	0.3	0.8	0.4	0.6	0.9	0.4	2.0
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.4	-1.6	-0.7	1.2	-1.4	-0.6	-0.1	-0.4	-0.4	-1.0	-0.7	-0.4	-0.0
Medication: Levothyroxine sodium	0.6	1.0	2.8	-0.2	-0.0	0.1	1.3	1.3	1.3	1.1	0.9	0.3	1.5	0.8	1.7
Weight	0.6	2.8	6.0	-0.5	-0.1	-0.9	2.4	2.0	1.4	2.2	1.7	1.1	2.3	1.1	2.2
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	11.5	-2.7	-1.2	-3.4	-0.3	0.6	-0.1	-0.3	-0.4	-0.9	-0.7	0.1	-1.2
Prospective memory result	0.6	0.7	1.7	1.2	-1.3	0.9	0.7	1.3	0.5	-0.0	0.5	-0.2	0.7	0.5	1.0
Pulse wave reflection index	0.6	0.7	5.3	0.3	0.3	-1.0	-0.9	-0.3	-0.1	-0.3	-0.3	-0.8	-0.4	-0.1	-2.3
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	4.6	-1.2	0.6	0.2	1.5	1.0	1.1	0.7	0.7	0.4	1.4	0.7	2.1
Medication: Amlodipine	0.6	0.8	1.8	-0.0	-0.8	0.6	0.5	0.9	1.3	1.3	1.2	0.4	1.2	0.9	0.3
Forced vital capacity (FVC), Best measure	0.6	2.2	15.5	-2.9	-0.5	-3.9	0.2	0.8	0.7	0.6	0.3	0.4	0.1	0.8	0.2
Age at first live birth	0.6	1.1	2.3	-1.4	-1.5	-1.5	0.2	-0.1	1.4	0.4	1.3	-0.0	0.8	1.5	0.0
Emphysema/chronic bronchitis	0.6	0.7	2.8	0.9	-0.6	1.7	0.2	0.7	0.7	0.8	0.5	0.1	0.3	0.5	-1.3
Whole body fat mass	0.6	2.4	6.6	1.1	0.4	0.3	2.6	1.9	1.4	1.5	1.5	1.2	2.0	1.2	1.9
Number of full sisters	0.6	0.7	1.7	-1.3	1.1	-0.9	-0.7	-0.9	-0.8	-0.2	-0.7	-1.3	-0.2	-0.7	-0.4
Suffer from ‘nerves’	0.6	1.0	5.3	-2.3	0.4	-1.0	-1.3	-0.4	-0.6	0.3	-0.7	-0.4	-0.8	-1.2	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	3.2	1.1	0.1	1.8	1.3	0.5	0.5	0.1	0.5	0.6	0.6	0.7	0.8
Illnesses of father: Heart disease	0.6	0.8	3.6	1.9	-1.0	1.4	0.6	-1.0	-0.3	-0.9	-0.1	-0.1	-0.1	0.7	-0.0
Smoking status: Previous	0.6	0.9	4.4	0.1	-0.6	1.5	0.6	1.1	0.5	-1.4	-0.3	0.3	-0.3	0.5	2.1
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	5.6	-0.8	2.4	-1.6	-0.8	-0.2	0.6	0.1	0.6	0.7	0.5	0.4	-0.8
Medication: Aspirin	0.6	0.8	2.3	-0.8	-1.3	-1.5	0.3	-0.9	-1.1	-0.3	-0.6	-1.5	-0.2	-0.5	0.3
Number of self-reported non-cancer illnesses	0.6	1.0	2.5	0.9	-0.7	0.8	1.4	0.8	1.2	0.9	1.1	-0.1	1.6	1.1	0.6
Average weekly champagne plus white wine intake	0.6	0.8	2.5	-0.4	1.4	-0.2	-1.3	-1.2	-0.6	-0.0	-0.5	-0.4	-0.6	-0.6	-1.6
Mother’s age at death	0.6	0.7	1.7	-1.2	1.0	-1.2	0.5	1.0	-0.1	-0.4	-0.2	1.3	-0.3	0.1	1.1
Medication: Atorvastatin	0.6	0.8	2.0	1.0	-1.2	0.6	0.3	-0.4	1.1	0.8	0.9	-0.4	0.3	1.1	-1.4
Alcohol drinker status: Never	0.6	0.7	2.3	-0.7	-1.4	-1.1	-1.1	-1.5	-0.3	-0.2	-0.4	-0.8	-0.6	-0.8	0.1
Myopia	0.6	0.8	3.0	-1.7	-1.3	-1.7	0.5	0.6	0.3	1.0	0.5	-0.0	0.4	0.6	-0.5
LDL Cholesterol	0.5	0.8	4.5	-0.7	0.7	2.1	0.5	1.2	0.2	-0.3	0.4	-0.5	0.8	0.6	0.8
BMI	0.5	2.6	5.9	-1.9	1.4	-1.1	1.4	2.4	1.4	1.8	1.5	1.4	1.8	0.9	1.9
Smoking Status	0.5	1.3	2.9	-0.5	-1.4	-0.2	-1.1	-0.5	-1.2	-1.1	-1.5	-1.6	-1.7	-1.1	-0.5
Neuroticism	0.5	1.2	6.2	-2.5	1.2	-1.9	0.4	1.1	0.2	0.9	0.2	1.0	-0.1	-0.1	-0.2
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	4.3	-0.1	2.1	0.7	-0.1	0.6	0.4	0.6	0.4	0.5	0.5	0.3	-0.3
Severe depression (siblings)	0.5	0.5	3.0	-0.3	0.5	0.3	-1.0	-0.9	-0.4	0.6	-0.2	-0.2	-0.1	-0.7	-1.7
Trunk fat percentage	0.5	1.9	4.8	2.2	0.9	1.8	2.1	1.1	1.1	0.7	1.1	0.9	1.4	1.0	1.4
Maternal smoking around birth	0.5	0.7	2.9	0.4	1.7	-0.8	-0.0	1.1	0.1	0.7	0.4	1.2	-0.1	0.2	-1.4
Fed-up feelings	0.5	0.8	3.6	-1.9	0.6	-1.6	-0.5	0.2	-0.8	0.1	-0.7	-0.3	-0.7	-1.0	0.4
Trunk fat mass	0.5	2.4	6.2	1.2	0.7	0.7	2.5	1.7	1.5	1.5	1.5	1.0	2.0	1.2	1.9
Forced vital capacity (FVC)	0.5	1.9	9.7	-3.0	-0.5	-3.1	-0.1	0.8	0.7	0.5	0.3	-0.2	-0.1	0.8	-1.3
Allergy	0.5	1.2	3.3	0.6	1.8	-0.1	0.6	0.8	1.3	1.0	1.3	1.5	1.3	1.2	0.6
Diabetes (self-reported)	0.5	0.8	3.0	0.7	0.6	0.4	1.2	0.8	0.3	1.7	0.9	0.8	1.4	0.3	0.6
Medication: Ramipril	0.5	0.6	3.2	1.0	-1.8	0.0	0.4	-0.2	-0.5	0.9	-0.2	-1.0	0.5	-0.5	0.6
Illnesses of siblings	0.5	0.7	1.5	-1.2	0.2	0.0	-0.6	0.4	-1.0	0.0	-1.0	-1.1	-0.8	-1.0	-0.9
Hip circumference	0.5	2.1	5.6	-0.2	0.1	-0.8	2.4	1.9	1.2	1.5	1.3	1.0	1.9	1.1	2.0
Father’s age at death	0.5	0.6	3.0	-0.7	-0.0	-1.7	0.1	-1.0	-0.9	-0.2	-0.7	-1.1	-0.2	-0.5	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.2	-0.6	-1.3	0.7	-0.8	-0.9	-1.0	-0.2	-1.0	-0.6	-1.0	-1.5	-0.1
Number of live births	0.5	0.6	2.8	-1.0	-0.3	-1.1	-0.0	0.5	0.3	0.6	0.7	0.5	0.5	0.9	-1.7
Asthma	0.5	0.9	4.0	0.0	-1.3	0.8	1.4	0.2	0.7	-0.5	0.4	-0.2	0.6	1.1	2.0
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.6	2.7	-0.4	0.8	-1.5	-0.5	0.3	-0.1	-0.3	-0.3	1.6	-0.4	-0.6	0.7
Arm fat mass (right)	0.5	2.3	5.4	0.6	0.8	0.2	2.3	2.2	1.2	1.7	1.4	1.5	1.9	0.9	1.8
Length of working week for main job	0.5	0.5	1.1	-0.1	1.0	-0.9	-0.7	-0.8	-0.9	-0.4	-0.4	1.0	-0.5	-0.6	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.7	1.5	0.3	0.6	-0.1	1.6	0.8	1.2	0.6	-0.6	0.6	0.3	-0.7
Medication: Ventolin 100micrograms inhaler	0.5	0.6	3.3	-0.2	-0.3	0.6	-0.1	0.2	-0.5	0.1	-0.7	0.8	-0.3	-1.3	1.8
Body fat percentage	0.5	2.0	6.0	2.5	1.1	1.6	2.1	1.2	1.0	0.7	1.0	1.1	1.4	0.8	1.4
Worry too long after embarrassment	0.5	0.9	3.6	-1.2	0.3	-1.9	-0.1	-0.7	-0.8	0.3	-0.5	0.2	-0.6	-1.0	-1.5
Wheeze or whistling in the chest in last year	0.5	0.8	3.8	-0.1	0.7	1.0	0.1	0.9	-0.3	-0.3	-0.9	1.0	-0.7	-1.2	2.0
Migraine (self-reported)	0.5	0.6	1.6	-0.3	-1.0	-1.3	0.3	-0.9	-0.7	-1.0	-0.6	-1.0	-0.6	0.2	-0.2
Medication: Ibuprofen	0.5	0.6	3.7	0.2	0.0	-1.3	0.4	0.1	0.5	0.0	0.4	1.9	0.5	0.1	1.3
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	2.0	-0.5	-0.7	-1.2	0.8	-0.3	-0.3	-1.4	-0.3	-0.9	-0.1	0.5	1.0
Hypertension (Self-reported)	0.5	1.4	3.5	-0.8	-0.5	-0.6	0.5	1.9	1.1	1.4	1.2	1.4	1.2	0.6	1.6
Arm fat mass (left)	0.5	2.0	4.9	0.5	0.9	0.3	2.2	1.9	1.2	1.6	1.3	1.4	1.8	0.9	1.6
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.1	0.5	1.4	0.5	0.5	-0.3	-0.2	0.8	0.0	1.0	0.4	-0.4	1.4
Commuting to job workplace: Public transport	0.5	0.6	2.6	-0.7	0.3	-0.1	0.1	-0.1	0.7	1.6	1.0	-0.4	1.3	0.4	0.9
Number of operations (self-reported)	0.5	0.8	3.4	0.4	1.0	0.9	-0.7	-0.7	-0.7	-1.1	-0.5	-0.4	-0.7	-0.0	-1.8
Unable to work because of sickness or disability	0.5	0.6	2.8	1.3	0.4	1.7	0.5	-0.1	-0.4	0.8	0.2	0.7	0.4	-0.6	0.6
Deep venous thrombosis (DVT) (self-reported)	0.5	0.7	1.6	-0.6	-0.1	0.6	-0.1	0.2	-1.3	-1.2	-1.2	0.7	-1.2	-0.8	-0.2
Depressed Affect (Nagel 2018)	0.4	0.8	3.1	-1.7	0.4	-1.8	-0.3	0.5	0.0	1.0	-0.1	1.1	-0.4	-0.6	0.4
Depression (Nagel 2018)	0.4	0.7	2.2	-0.5	-0.7	0.1	-1.5	-0.3	-0.4	-0.4	-1.0	-0.5	-1.3	-1.2	-0.6
Neuroticism (Nagel 2018)	0.4	1.0	3.8	-1.9	-0.1	-2.0	0.1	0.4	0.3	1.7	0.3	1.1	0.0	-0.5	-0.6
Worry (Nagel 2018)	0.4	0.9	4.8	-2.2	-0.2	-1.6	-0.3	0.3	0.3	1.2	0.1	-0.2	-0.1	-0.4	-1.3
Alzheimer’s Disease (in mother)	0.4	0.4	1.1	1.0	-0.5	0.5	-0.6	-1.0	-0.7	0.5	-0.4	-0.7	0.2	-0.8	0.5
Irritable Bowel Disease (IBD)	0.4	0.9	3.1	0.9	1.1	-0.2	-0.7	-1.3	-0.8	-1.8	-0.8	0.1	-0.7	-0.5	1.1
Ulcerative Colitis (UC)	0.4	0.7	2.4	0.7	-0.4	-1.1	-0.9	-0.9	-0.5	-1.0	-0.5	-0.5	-0.5	-0.5	1.5
Crohns Disease (2012)	0.4	0.6	4.0	0.7	2.0	-0.4	-0.5	-0.4	-0.7	-0.8	-0.7	0.2	-0.4	-0.7	-0.4
Mean Putamen Volume	0.4	0.4	1.6	-0.4	-0.6	1.3	-0.3	-0.4	0.2	1.0	0.4	-0.7	0.4	0.2	-0.7
Systolic Blood Pressure	0.4	1.9	4.3	-0.1	-2.0	-1.9	-0.3	0.2	1.0	2.0	1.1	-2.1	1.1	0.9	-1.8
Respiratory disease	0.4	0.9	3.7	-1.3	0.2	0.1	0.4	1.7	1.0	0.4	0.6	-0.0	0.7	0.9	1.9
Average weekly spirits intake	0.4	0.5	1.4	0.9	1.1	0.6	0.5	-0.4	0.5	-0.1	0.7	0.8	0.4	1.2	-0.1
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.2	-0.0	-0.5	-1.1	-0.6	0.0	-0.8	-0.4	-1.0	-0.2	-1.1	-1.5	0.3
Ever used hormone-replacement therapy (HRT)	0.4	0.4	2.0	0.1	0.7	-0.6	-0.6	-0.5	-0.3	-0.7	-0.5	1.4	-0.9	-0.3	0.5
Serious illness, injury or assault to yourself	0.4	0.5	2.7	-0.7	-1.0	-0.5	0.1	-0.1	0.7	1.6	0.5	-0.1	0.5	0.1	-0.4
High blood pressure	0.4	1.2	3.3	-0.4	-0.3	-0.1	0.6	1.8	1.1	1.3	1.1	1.3	1.1	0.6	1.6
Impedance of leg (left)	0.4	2.0	7.8	2.8	0.8	1.9	-1.0	-1.7	-0.6	-1.3	-0.8	-0.9	-1.1	-0.4	-1.9
Number of incorrect matches in round	0.4	0.6	2.1	0.3	1.4	0.5	0.7	1.1	0.7	0.3	0.8	0.3	0.7	0.9	-0.7
Past tobacco smoking	0.4	0.7	3.4	-0.1	0.6	-1.9	-0.3	-0.5	0.0	1.2	0.6	0.1	0.5	-0.1	-1.5
Had other major operations	0.4	0.4	1.4	0.0	-0.2	-0.1	-0.6	0.6	-1.2	-1.1	-0.8	-0.1	-0.9	-0.8	-0.2
Arm fat percentage (right)	0.4	1.5	3.2	1.4	1.2	1.2	1.8	1.7	0.6	0.9	0.8	1.2	1.1	0.4	1.4
Medication: Cholesterol lowering	0.4	0.6	1.8	0.3	-1.3	0.4	0.5	0.3	0.3	1.0	0.4	-1.3	0.9	0.3	1.0
Hair/balding pattern: Pattern 4	0.4	0.9	1.8	-1.3	0.0	0.1	0.2	1.1	1.2	1.0	1.1	-1.1	1.2	0.9	0.8
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.4	0.5	-0.0	0.7	-0.8	0.1	-0.8	0.0	-0.9	-0.3	-0.7	-0.9	-1.2
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	3.5	-1.9	0.6	-0.7	-0.6	0.1	0.1	-1.0	-0.4	-0.4	-0.6	-0.1	-0.5
Headache pain in last month	0.4	0.7	1.5	0.1	1.2	-1.0	0.8	-0.1	0.4	1.1	0.8	1.2	1.0	0.7	-0.3
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.6	-0.5	1.4	-0.9	-0.5	-0.5	0.0	-0.8	-0.3	0.5	-0.9	-0.0	-1.6
Qualifications: College or University degree	0.4	1.3	1.8	-1.0	-1.0	-1.2	-0.8	-1.3	-1.1	-1.1	-1.3	-1.2	-1.3	-1.2	-0.4
Medication: Blood pressure	0.4	0.6	2.5	0.6	-0.5	0.5	0.6	1.0	0.4	0.9	0.7	0.4	1.1	0.5	1.6
Medication: Allopurinol	0.4	0.5	1.3	-0.2	-0.1	0.7	-0.1	0.6	1.0	1.1	1.0	0.6	0.9	0.3	0.1
Age at last live birth	0.4	0.5	1.9	-0.6	-1.4	-1.2	-1.1	-0.4	0.3	-0.1	0.2	-1.0	-0.1	0.1	-0.2
Commuting to job workplace: Car/motor vehicle	0.4	0.4	1.4	-0.2	0.5	-0.2	0.7	-1.0	-0.6	-1.2	-0.5	0.8	-0.5	0.1	0.7
Illnesses of siblings: Diabetes	0.4	0.5	2.0	1.4	-0.2	-0.7	0.4	-0.4	-0.9	-1.2	-0.7	-0.2	-0.5	-0.5	0.6
Arm fat percentage (left)	0.4	1.5	3.6	1.7	1.0	1.4	1.9	1.5	0.8	0.8	0.8	1.1	1.2	0.6	1.2
Handedness (chirality/laterality): Left-handed	0.4	0.4	3.8	-0.0	-1.9	-0.2	0.6	-0.3	-0.0	0.5	0.2	-0.6	0.4	0.1	0.4
Eye problems/disorders: Cataract	0.4	0.5	1.6	1.0	0.4	0.4	0.6	0.7	0.5	0.8	0.2	1.3	0.2	-0.4	1.1
Back pain experienced in last month	0.4	0.5	1.6	-1.3	0.4	-0.7	-0.9	-0.0	-0.4	-0.7	-0.7	0.9	-0.8	-0.9	0.3
Breast cancer (self-reported)	0.4	0.5	2.9	0.1	-0.8	1.7	-0.1	-0.0	0.7	0.5	0.5	-1.1	0.5	0.5	-0.0
Asthma (self-reported)	0.4	0.7	3.3	-0.0	-1.3	0.8	1.0	-0.3	0.4	-0.9	0.1	-0.3	0.3	0.8	1.8
Eye problems/disorders: Glaucoma	0.4	0.4	1.6	-0.3	0.3	0.2	0.2	0.2	0.9	0.3	0.7	-0.4	1.1	0.9	1.3
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.3	1.1	-0.1	0.1	1.0	-0.9	0.4	-0.1	0.6	1.2	0.6	0.9	-0.3
Average weekly beer plus cider intake	0.4	0.6	0.9	-0.9	-0.1	0.9	0.9	0.5	0.9	0.9	0.8	0.1	0.9	0.7	0.6
Diastolic blood pressure, automated reading	0.4	1.3	2.8	1.5	-0.6	-0.2	1.5	1.4	1.0	1.3	1.3	0.2	1.7	1.4	0.2
Prostate Cancer	0.3	0.4	1.4	0.4	1.0	0.6	0.7	0.5	0.2	-0.0	0.2	0.7	0.4	0.1	1.2
Bipolar Disorder (2011)	0.3	0.3	1.2	-0.6	0.2	-0.8	0.0	0.4	-0.4	0.0	-0.8	-1.1	-0.3	0.0	0.7
Body Mass Index (BMI) (2010)	0.3	0.4	2.2	0.3	0.0	0.1	-0.3	-0.5	-0.5	-1.5	-0.6	0.2	-0.9	-0.5	0.1
HbA1C	0.3	0.4	1.0	-0.4	-1.0	0.8	-0.1	-0.6	-0.6	0.2	-0.4	0.0	0.0	-0.9	1.0
Primary Biliary Cirrhosis	0.3	0.5	2.3	0.9	0.2	-0.6	-0.2	0.4	-0.8	-0.6	-0.6	-0.3	-0.5	-0.5	-1.5
Type 2 Diabetes (T2D) (2012)	0.3	0.3	1.8	-1.3	-0.2	-1.3	-0.2	0.0	0.2	0.2	0.1	-0.1	0.2	-0.1	-0.1
Blood Red Count	0.3	3.0	12.0	-3.5	-1.7	-1.5	-0.7	1.6	0.7	3.1	1.2	-1.4	1.5	-0.4	0.2
Waist Hip Ratio (WHR)	0.3	1.6	2.8	0.6	1.3	1.5	1.1	1.7	1.4	1.0	1.4	0.9	1.4	1.1	1.2
Lung FEV1/FVC ratio	0.3	1.7	10.4	0.8	-3.2	-1.2	0.2	0.0	-1.3	-0.9	-1.1	-1.6	-0.8	-1.0	-0.0
Lung FVC	0.3	1.4	4.6	-0.9	-1.4	-2.1	-1.1	-0.2	-0.5	-0.8	-0.7	-1.3	-1.2	-0.2	-1.8
Chronotype (morning person)	0.3	0.7	2.0	-1.4	-0.9	0.8	0.7	1.0	0.6	0.7	0.7	-0.1	0.7	0.9	0.3
Hand grip strength (left)	0.3	0.9	3.3	0.4	-0.9	-1.1	1.0	0.4	1.2	0.5	1.1	-0.6	1.0	1.8	0.1
Systolic blood pressure, automated reading	0.3	0.8	2.3	0.8	-1.4	-0.6	-0.0	0.0	0.8	0.7	0.8	-1.0	0.8	1.0	-1.5
Medication: Co-codamol	0.3	0.4	0.9	-0.4	-0.6	-0.1	-0.7	-1.0	-0.6	-0.4	-0.5	-0.9	-0.2	-0.7	0.2
Hand grip strength (right)	0.3	0.9	3.4	-0.4	-0.3	-1.6	0.3	0.4	1.2	0.3	1.0	-0.6	0.7	1.9	-0.9
Age when periods started (menarche)	0.3	0.7	4.0	-0.9	0.3	-2.0	-0.0	1.2	0.8	0.5	0.6	-0.2	0.4	0.7	0.3
Chronic bronchitis/emphysema (father)	0.3	0.4	1.5	-1.2	-0.8	-0.1	-0.6	-0.7	-0.2	-1.0	-0.5	-0.4	-0.5	-0.2	0.6
Body mass index (BMI)	0.3	1.2	3.1	0.3	0.6	-0.1	1.8	1.7	0.7	1.3	0.9	1.1	1.4	0.4	1.5
Fluid intelligence score	0.3	0.6	3.0	-1.5	-0.2	-1.7	-0.3	0.1	-0.3	-0.4	-0.3	-0.4	-0.5	-0.1	-0.8
Worrier / anxious feelings	0.3	0.5	3.6	-1.9	-0.0	-1.2	0.8	0.1	-0.3	0.4	-0.0	0.1	-0.0	-0.3	-0.3
Hair/balding pattern: Pattern 3	0.3	0.5	2.6	-0.3	1.6	-0.3	0.7	-0.1	0.3	-0.6	0.3	0.9	0.1	0.7	-0.7
Mouth/teeth dental problems: Dentures	0.3	0.5	1.3	1.0	0.1	1.0	-0.6	-0.9	-0.3	-0.4	-0.3	-0.8	-0.4	-0.3	-1.1
Impedance of arm (left)	0.3	1.3	7.6	1.9	0.4	2.8	-0.5	-1.0	0.2	-0.9	-0.3	-0.4	-0.9	0.2	-1.1
Standing height	0.3	3.2	5.9	-1.7	-1.3	-2.0	1.9	1.2	1.9	2.4	2.0	0.1	2.3	1.8	1.5
Qualifications: O levels/GCSEs or equivalent	0.3	0.5	2.3	-0.8	0.3	-1.5	0.1	-1.0	-0.1	0.5	-0.0	0.1	-0.0	-0.4	1.2
Glaucoma (self-reported)	0.3	0.4	1.7	-1.3	-0.2	-0.7	-0.5	0.1	-0.3	-0.5	-0.6	-0.9	-0.3	-0.3	0.7
Chronic bronchitis/emphysema (mother)	0.3	0.4	2.3	-0.4	-0.2	0.0	-0.4	1.0	0.1	-0.3	-0.1	0.3	-0.6	0.1	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	1.4	1.2	0.4	1.1	0.2	1.0	0.4	-0.1	0.1	-0.2	-0.0	-0.0	-0.4
Heart disease (mother)	0.3	0.3	1.9	-0.3	-0.2	0.2	0.3	0.7	0.6	0.1	0.5	0.6	0.4	0.5	1.4
Alcohol intake frequency.	0.3	0.6	3.9	0.5	-0.1	2.0	-0.8	-0.2	-0.5	-0.3	-0.7	-0.5	-0.7	-0.9	-0.4
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	2.0	0.8	-0.4	1.4	0.3	0.5	-0.1	-0.7	-0.1	-0.2	-0.2	0.2	-0.4
Average weekly red wine intake	0.3	0.4	1.5	0.4	-0.1	-0.1	0.8	0.5	0.6	1.2	0.6	-0.1	0.9	0.7	0.8
Diabetes diagnosed by doctor	0.3	0.5	1.8	0.4	0.3	1.0	0.8	0.1	0.1	1.3	0.6	0.3	1.1	0.1	0.4
Friendships satisfaction	0.3	0.3	0.8	0.8	0.9	-0.7	-0.5	0.2	-0.7	-0.7	-0.5	-0.2	-0.3	-0.2	-0.6
Mineral and other dietary supplements	0.3	0.4	1.4	-0.1	0.6	1.2	-1.0	0.4	0.2	0.8	-0.2	-1.0	-0.2	-0.6	-0.1
Medication: Gliclazide	0.3	0.4	1.4	0.4	0.9	0.5	0.5	0.2	0.0	0.7	0.3	1.2	0.4	-0.0	-0.9
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.2	-1.0	-0.9	0.4	0.7	-0.2	0.1	0.1	0.1	0.2	0.4	0.1	1.1
Medication: Omeprazole (e.g. Zanprol)	0.3	0.4	1.4	1.1	-0.3	1.2	1.0	-0.3	0.0	0.3	0.3	-0.1	0.6	0.4	0.7
Impedance of whole body	0.3	1.7	6.5	2.5	0.4	2.6	-0.8	-1.3	0.1	-0.8	-0.3	-0.5	-0.9	0.2	-1.9
Breast Cancer	0.2	0.6	1.6	0.1	0.5	0.8	0.3	-1.3	0.3	0.8	0.5	1.2	0.7	0.0	1.2
HDL Cholesterol	0.2	0.4	3.1	-0.3	-0.5	-0.3	0.2	0.5	0.3	0.1	0.3	-0.4	0.7	0.3	1.8
Relative age of first facial hair	0.2	0.3	0.9	-0.8	0.1	-0.1	-0.5	-0.3	-0.8	-0.7	-0.8	-0.0	-0.9	-0.4	0.1
Impedance of leg (right)	0.2	1.2	5.9	2.4	0.8	1.4	-0.9	-1.2	0.2	-0.3	-0.1	-0.3	-0.4	0.1	-1.7
Relative age voice broke	0.2	0.3	0.8	-0.3	0.9	0.9	0.1	0.1	-0.8	-0.6	-0.6	-0.4	-0.6	-0.3	-0.2
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	1.0	0.7	-0.9	-0.5	-1.0	-0.5	-0.2	-0.1	-0.1	-0.1	-0.1	-0.3	0.1
Qualifications: CSEs or equivalent	0.2	0.2	0.6	0.7	0.6	-0.3	-0.5	0.3	-0.7	0.1	-0.4	-0.7	-0.2	-0.4	-0.4
Sitting height	0.2	1.2	4.7	-2.0	-0.7	-2.2	0.6	-0.3	0.8	1.0	0.5	0.3	0.6	0.6	1.4
Had menopause	0.2	0.2	0.6	0.4	-0.7	0.5	-0.2	0.7	0.3	-0.7	0.3	0.2	-0.2	0.8	-0.2
Birth weight	0.2	0.4	1.4	0.9	-0.6	0.5	-1.2	-0.2	-0.1	0.2	-0.2	-0.5	-0.6	-0.7	-0.7
Medication for pain relief, constipation, heartburn	0.2	0.4	2.7	0.9	-0.6	1.6	0.3	0.2	0.2	0.1	-0.2	-0.1	-0.4	-0.4	0.7
Overall health rating	0.2	0.5	1.0	0.9	0.0	1.0	-0.1	-0.3	-0.8	-0.9	-0.8	0.8	-0.7	-1.0	0.3
Financial situation satisfaction	0.2	0.3	1.1	-1.0	-0.3	-0.6	0.2	0.7	-0.1	-0.7	-0.2	0.4	-0.3	0.1	0.5
Supplements: Calcium	0.2	0.3	1.0	1.0	-0.2	0.6	0.0	-1.0	-0.3	-0.7	-0.2	-0.2	-0.2	0.6	-0.0
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.9	0.6	-1.1	-1.4	0.7	0.2	0.1	0.3	0.2	0.2	0.4	0.3	-0.2
Verbal and Numeric Reasoning (VNR)	0.1	0.2	1.0	-0.6	-0.5	-1.0	0.8	0.4	0.0	0.0	0.1	0.6	0.0	0.2	-0.0
Blood Eosinophil Count	0.1	0.5	2.1	-1.4	-0.0	-1.2	-1.0	0.6	0.3	0.2	-0.0	-1.0	-0.2	-0.1	-0.0
Height	0.1	2.1	6.0	-1.1	-2.2	-2.5	0.7	-0.9	1.2	1.9	1.6	-0.1	1.6	1.0	0.6
Hypothyroidism (self reported)	0.1	0.3	1.4	-1.0	0.2	0.5	0.5	0.4	0.3	0.5	0.0	-0.1	0.6	-0.2	1.2
Tanning	0.1	0.6	1.6	0.0	0.2	0.1	-0.6	0.2	-1.2	-0.4	-1.2	-0.7	-0.7	-1.3	1.2
Supplements: Zinc	0.1	0.2	0.6	0.7	-0.1	0.0	-0.5	-0.8	0.2	-0.3	0.0	0.0	-0.3	0.1	0.5
Mouth/teeth dental problems	0.1	0.2	0.6	0.4	-0.8	0.1	0.3	0.1	-0.6	0.2	-0.4	-0.0	-0.4	-0.5	0.6
Impedance of arm (right)	0.1	0.7	3.6	1.3	0.6	1.9	-0.3	-0.4	-0.2	-0.8	-0.5	-0.3	-1.0	-0.1	-0.4
Tense / ‘highly strung’	0.1	0.2	1.5	-0.8	-1.2	-0.3	0.1	0.0	-0.1	-0.3	-0.2	-0.2	-0.4	-0.2	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.3	-0.0	0.3	-0.1	-0.2	-0.5	-0.1	-0.4	-0.2	-0.3	-0.1	0.3	0.1
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.8	0.1	-0.3	-0.1	0.0	-0.6	-0.2	0.9	0.0	-0.6	0.5	-0.5	0.0
Family relationship satisfaction	0.1	0.1	0.3	0.1	0.4	0.0	-0.4	0.6	-0.2	-0.5	0.1	-0.1	0.1	0.2	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.6	-0.4	-0.1	0.7	0.3	0.1	0.1	0.1	-0.1	0.3	-0.2	0.0	-0.0
Osteoporosis (self-reported)	0.1	0.2	0.7	-0.7	-0.2	-0.8	0.1	-0.4	0.1	0.3	0.4	0.2	0.3	0.3	0.1
Ever smoked	0.1	0.1	0.3	-0.6	-0.6	0.3	-0.0	0.6	0.1	-0.3	-0.2	-0.6	-0.1	0.1	0.3
Hair Pigment	0.0	0.8	2.2	0.6	-0.4	1.0	-1.5	-1.1	-0.6	-0.0	-1.1	-0.7	-1.1	-1.4	-0.4

Hub : Genes

SLC1A1

Models

Trait associations