Hub : Genes

SLC1A5

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.3050	0.0550	3.7e-11	0.327	NA	0.324	NA	0.332	3.5e-25	NA	6.9e-25	NA	1.2e-25
2	GTEx	Nerve Tibial	0.1551	0.0645	5.5e-03	0.046	NA	0.009	NA	0.009	3.3e-04	NA	7.5e-02	NA	7.3e-02
3	METSIM	Adipose	0.1155	0.0378	1.6e-05	0.018	0.042	0.065	0.048	0.024	9.7e-04	6.6e-07	4.9e-10	8.7e-08	1.2e-04
4	YFS	Blood	0.0728	0.0205	1.0e-07	0.033	0.034	0.051	0.046	0.044	4.0e-11	2.8e-11	2.2e-16	6.3e-15	3.2e-14
5	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0680	0.0350	6.6e-03	0.017	0.033	0.017	NA	0.009	3.4e-02	5.2e-03	3.5e-02	NA	9.2e-02
6	TCGA	Brain Lower Grade Glioma	0.0695	0.0335	5.9e-04	0.012	0.031	0.030	NA	0.020	1.3e-02	1.9e-04	2.2e-04	NA	2.2e-03
7	TCGA	Prostate Adenocarcinoma	0.0492	0.0236	2.6e-03	-0.001	0.025	0.014	NA	0.006	4.5e-01	9.9e-04	1.2e-02	NA	7.1e-02
8	TCGA	Thyroid Carcinoma	0.2230	0.0620	5.8e-06	0.119	0.051	0.105	NA	0.113	1.3e-11	9.0e-06	2.1e-10	NA	4.4e-11

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.1	0.2	0.3	-0.5	0.0	0.1	-0.6	0.6	-0.4	-0.6	0.0
Bipolar Disorder or Schizophrenia	0.4	0.9	3.1	1.8	0.0	-0.5	-0.2	-1.2	1.5	-0.4	0.0
Depressed Affect (Nagel 2018)	0.3	0.7	1.6	1.3	1.0	0.2	0.6	-1.0	0.5	0.1	-1.2
Depression (Nagel 2018)	0.4	0.5	2.1	-0.2	-0.5	0.1	-0.4	0.3	-0.1	1.4	-1.2
Intelligence (Savage-Jansen 2018)	0.1	0.4	1.1	0.6	0.9	0.5	0.3	-0.4	0.0	-0.3	1.0
Neuroticism (Nagel 2018)	0.1	0.2	0.8	0.2	0.2	-0.2	0.3	0.1	-0.1	0.7	-0.9
Schizophrenia (2018)	1.0	2.2	6.9	2.6	0.0	-0.8	0.2	-1.9	2.4	0.1	0.5
Schizophrenia vs Biploar Disorder	0.1	0.2	1.1	0.3	0.0	0.0	1.1	0.0	0.0	0.0	0.0
Worry (Nagel 2018)	0.3	0.6	1.1	-1.1	-1.0	-0.5	0.2	1.0	-0.6	1.0	-0.5
Alzheimer’s Disease (in mother)	2.9	3.4	9.3	2.9	1.9	-0.4	0.0	-3.0	-0.3	-1.9	1.4
Alzheimer’s Disease (in father)	1.8	2.0	5.8	1.7	2.4	-1.2	1.6	-0.4	0.1	0.1	-1.8
Alzheimer’s Disease (including proxy)	2.0	2.9	7.6	2.8	2.5	-1.0	1.8	-2.1	0.3	-0.8	0.6
Crohns Disease (2017)	0.2	0.5	1.3	-1.2	-1.2	0.3	0.3	0.7	-0.0	-0.7	-0.2
Irritable Bowel Disease (IBD)	0.4	1.0	3.0	-1.7	-1.3	-0.6	0.6	1.1	-0.8	-1.0	-0.2
Ulcerative Colitis (UC)	0.8	1.5	3.0	-1.7	-1.2	-1.6	0.0	0.6	-1.6	-1.3	0.2
Major Depression (MDD)	0.6	0.8	3.0	0.6	0.0	1.7	-0.0	1.1	-0.1	0.8	-1.0
Reaction Time	1.4	2.6	5.7	-1.8	-1.6	-0.1	-0.7	2.4	-2.2	-0.3	-1.9
Verbal and Numeric Reasoning (VNR)	0.3	0.8	1.5	0.7	0.9	1.1	-1.2	-1.2	0.3	-1.0	-0.0
Breast Cancer	1.1	2.6	7.6	2.1	2.7	1.0	0.2	-0.7	2.8	0.1	0.1
Ovarian Cancer	1.7	2.2	5.8	-2.4	-2.0	-1.8	-0.8	1.7	-0.9	-0.5	0.4
Prostate Cancer	1.7	2.4	4.0	1.9	1.7	1.0	2.0	-1.0	1.8	1.7	0.5
Age at First Birth	0.9	1.2	4.3	0.4	0.0	-0.7	-1.2	-1.4	-1.2	-2.1	0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.1	0.2	0.5	0.2	0.0	-0.4	-0.1	-0.3	0.7	-0.3	-0.7
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.2	0.3	0.9	-0.5	0.0	-0.8	-0.2	0.4	-0.9	-0.6	0.0
Mean Putamen Volume	1.2	1.3	5.8	-0.1	0.0	1.6	1.1	0.7	-0.3	0.6	-2.4
Fasting Glucose	0.3	0.3	1.5	-0.3	0.0	0.2	0.8	1.2	0.2	0.0	-0.7
HbA1C	0.9	1.0	3.1	0.7	0.0	0.6	-1.8	-1.1	-0.2	-1.7	0.3
HDL Cholesterol	0.1	0.1	0.4	-0.0	0.0	-0.6	0.1	0.3	-0.3	0.6	-0.0
LDL Cholesterol	0.8	1.3	4.0	1.2	0.0	0.2	-0.5	-2.0	-1.1	-1.5	-1.0
Lupus	0.5	0.7	2.8	0.5	0.5	0.2	1.3	0.7	-0.1	0.7	-1.7
Neuroticism (2016)	1.3	1.8	6.0	-0.3	-0.3	-1.0	1.5	0.4	2.4	0.9	2.1
Primary Biliary Cirrhosis	1.3	1.9	4.0	-2.0	0.0	-1.8	-2.0	0.6	-1.7	0.4	0.0
Rheumatoid Arthritis	0.2	0.3	0.5	0.6	0.0	-0.1	-0.6	-0.6	-0.7	-0.6	-0.5
Schizophrenia (2014)	0.4	0.8	2.5	1.6	0.0	-0.1	0.1	-1.4	1.2	-0.6	0.4
Triglycerides	0.9	1.5	4.2	0.5	0.0	-0.1	-2.0	-2.1	-0.4	-1.8	0.5
Type 2 Diabetes (T2D) (2012)	0.7	0.9	3.3	-1.8	0.0	0.0	-0.6	1.2	-0.8	0.3	1.0
Ulcerative Colitis	0.2	0.3	1.9	-1.4	0.0	-0.5	0.6	0.0	0.0	0.0	0.0
Blood Eosinophil Count	0.3	2.0	5.1	-2.0	-2.0	-1.3	0.3	2.2	0.1	0.8	-0.8
Blood Platelet Count	0.6	7.0	14.6	1.6	1.4	-3.0	2.3	2.1	3.8	3.6	-2.1
Blood Red Count	0.3	2.6	13.6	-0.5	0.1	-3.7	-2.2	0.7	0.1	-1.1	0.4
Blood White Count	0.4	2.9	17.9	-1.2	-1.3	-4.2	-0.7	0.5	1.1	0.4	0.3
Heel T-Score	1.2	9.6	30.9	-3.9	-2.8	-0.1	1.6	5.6	1.6	3.9	-1.8
BMI	0.3	1.6	6.0	-0.2	-0.6	2.5	-1.0	-0.7	-1.1	-1.8	0.1
Height	0.8	16.3	41.7	-5.1	-6.5	-1.7	-3.8	-1.3	-5.2	-2.8	2.9
Waist Hip Ratio (WHR)	0.4	1.6	6.5	-1.2	-1.0	-0.3	0.9	2.5	-0.3	1.7	-0.5
Systolic Blood Pressure	0.2	0.8	2.9	0.6	-0.0	0.3	-1.1	-0.2	-0.9	-0.8	-1.7
Smoking Status	0.7	1.6	4.9	1.0	0.2	2.2	-0.2	-1.1	-1.3	-1.6	-1.2
Allergy or Eczema	0.8	2.1	5.5	0.5	0.3	2.4	1.8	1.4	1.4	1.3	1.4
Cardiovascular Disease	0.2	0.7	2.6	-0.2	-0.6	1.6	-0.1	0.1	-1.1	0.4	-0.9
Hypothyroidism (self reported)	2.0	4.6	14.2	-1.2	-0.5	1.0	2.8	2.2	0.9	3.8	-2.5
Respiratory disease	0.7	1.5	4.0	0.4	-0.1	-0.0	-1.7	-1.1	-1.9	-2.0	-0.2
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.1	-0.1	-0.1	1.3	-0.4	0.5	-0.6	0.1	-1.5
Lung FEV1/FVC ratio	0.5	2.7	8.6	-2.9	-2.3	0.8	0.6	2.4	-0.9	-0.4	-0.1
Lung FVC	0.5	2.7	9.7	-0.4	-0.3	-3.1	-2.8	0.1	-0.5	-1.0	-1.6
Neuroticism	0.3	0.6	1.9	0.7	0.6	-1.4	0.3	-1.0	0.2	0.3	0.9
Chronotype (morning person)	0.7	1.6	3.9	-1.5	-1.4	-2.0	-0.6	1.3	-1.0	1.2	-0.6
Hair Pigment	0.1	3.0	7.3	1.4	1.5	-0.9	-2.5	-1.8	-1.5	-2.7	0.1
Tanning	0.1	1.0	1.9	1.2	1.0	0.2	0.1	-1.4	1.4	-0.3	-1.2
Hand grip strength (left)	0.1	0.2	0.9	0.2	-0.0	-0.0	0.9	-0.1	-0.0	-0.5	-1.0
Number of treatments/medications taken	0.1	0.3	1.0	0.6	0.3	0.1	0.2	-0.7	0.4	1.0	-0.0
Average weekly spirits intake	0.2	0.2	0.8	0.3	0.1	0.3	-0.3	-0.4	-0.5	0.9	-0.6
Sensitivity / hurt feelings	0.7	1.1	4.4	-0.8	-0.7	-0.8	-0.8	0.7	-2.1	-1.0	0.8
Frequency of depressed mood in last 2 weeks	1.0	1.4	3.8	0.8	0.3	-0.5	-2.0	-1.1	-1.9	-1.1	-0.7
Hearing difficulty/problems: Yes	0.5	0.8	2.4	0.9	1.5	-0.6	0.8	0.5	1.1	0.5	-0.5
Relative age of first facial hair	0.2	0.4	1.3	0.6	0.4	-0.9	0.7	0.2	1.2	0.2	-0.6
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	2.9	1.6	1.3	-1.7	0.9	-1.4	0.7	0.4	-1.6
Ever used hormone-replacement therapy (HRT)	0.7	0.9	3.1	0.4	0.5	-1.0	-1.3	-1.8	0.6	0.6	0.5
Ever had hysterectomy (womb removed)	0.8	1.0	4.2	-0.6	-0.3	0.2	0.5	1.2	0.9	2.1	-0.6
Systolic blood pressure, automated reading	0.3	0.9	2.8	1.7	1.3	0.1	-0.5	-0.6	0.6	0.6	-1.3
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	1.8	-1.2	-1.0	-0.1	-0.9	0.4	-1.4	-0.5	-0.2
Angina	0.8	1.0	2.0	1.2	1.3	1.0	0.1	-1.0	0.7	-0.6	1.4
Medication for hormone replacement therapy	1.0	1.2	2.8	1.7	1.7	0.5	0.5	-1.6	-0.4	-0.6	-0.2
Vitamin and mineral supplements	0.3	0.5	2.0	0.1	0.6	0.2	1.4	1.1	0.3	0.3	-0.2
Supplements: Zinc	0.5	0.5	3.6	-0.2	-0.4	-0.7	0.2	-1.9	-0.0	-0.3	-0.1
Medication: Co-codamol	0.9	1.0	4.6	-0.9	-0.6	-0.3	0.5	1.2	0.1	2.1	-0.7
Medication: Metformin	0.5	0.7	1.4	-0.8	-0.9	0.8	-0.9	0.1	-0.9	-1.2	-0.8
Diabetes (father)	0.4	0.5	1.7	0.2	0.4	1.3	-0.1	0.0	-0.8	-1.1	-0.3
Diabetes (mother)	0.3	0.3	0.7	-0.8	-0.7	0.4	-0.2	0.6	-0.8	0.4	-0.1
Severe depression (siblings)	2.3	2.5	7.6	2.3	2.8	0.7	1.2	-1.4	1.0	-0.7	1.4
Pack years adult smoking proportion	0.3	0.5	1.5	1.2	0.9	0.3	0.9	-0.3	0.4	-0.3	-0.1
Impedance of leg (right)	1.3	6.5	17.4	3.9	4.2	-2.5	1.8	-2.4	2.0	0.4	-0.1
Leg fat-free mass (left)	1.1	5.8	12.1	-2.7	-3.5	1.9	-2.2	-0.3	-3.2	-2.7	1.0
Trunk fat percentage	0.9	3.4	11.2	2.1	1.5	0.5	-1.6	-3.3	-0.6	-2.3	1.1
Hand grip strength (right)	0.2	0.6	3.0	-0.4	-0.9	-0.3	1.7	0.7	0.3	-0.0	-0.6
Townsend deprivation index at recruitment	0.2	0.2	0.8	0.3	0.1	-0.2	0.1	-0.7	-0.6	-0.9	0.2
Current tobacco smoking	0.8	1.3	2.6	-1.1	-1.6	1.0	0.1	1.4	-1.3	-0.5	-1.2
Average weekly fortified wine intake	0.5	0.5	1.2	-1.0	-0.8	-1.0	-0.4	-0.2	-1.1	0.5	0.1
Maternal smoking around birth	0.4	0.6	1.3	1.0	0.9	0.2	0.8	-1.2	0.6	-0.6	-0.4
Fed-up feelings	0.4	0.7	3.8	0.0	-0.6	-0.7	0.4	-0.5	-0.4	0.7	-2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	2.9	-0.8	-1.1	-0.6	0.4	0.9	-0.2	1.7	-0.7
Relative age voice broke	1.2	1.9	5.2	0.0	0.0	-1.6	-1.3	-1.4	-1.2	-2.3	1.6
Taking other prescription medications	0.6	0.9	2.9	0.4	0.3	0.6	1.2	-0.4	-0.9	1.7	-1.2
Age when periods started (menarche)	0.3	0.8	1.7	-0.8	-1.3	-1.1	0.2	-0.0	-0.9	-0.7	-1.2
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	3.7	0.1	0.3	-1.9	-1.0	-0.8	0.3	0.7	-0.9
Heel bone mineral density (BMD) T-score, automated (left)	2.4	5.4	10.8	-3.0	-2.5	-2.0	0.9	3.3	0.5	3.1	-1.7
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	1.8	-0.5	-0.6	1.1	0.5	1.3	-1.1	1.1	-0.1
Qualifications: CSEs or equivalent	1.9	2.6	6.1	2.5	2.4	-0.3	0.9	-1.5	1.2	0.3	-2.0
Serious illness, injury or assault to yourself	1.9	2.3	4.3	1.6	1.3	-0.8	-2.1	-2.0	-1.0	-1.9	-0.8
High blood pressure	0.1	0.4	0.9	-0.6	-0.6	0.5	-0.5	1.0	0.3	0.8	0.1
Hayfever, allergic rhinitis or eczema	0.9	1.9	4.8	0.4	0.2	2.2	1.4	1.4	1.5	1.3	1.4
Multivitamins +/- minerals	0.4	0.5	1.8	-1.1	-1.3	-0.3	-0.3	0.2	0.1	0.9	0.0
Stomach or abdominal pain in last month	1.1	1.3	4.2	1.6	1.5	0.8	0.2	-0.6	2.0	-0.1	-0.9
Supplements: Glucosamine	0.8	1.0	3.2	0.3	-0.2	-0.3	-1.7	-1.8	-0.8	-0.4	0.9
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	1.7	-1.1	-0.9	-0.6	-0.4	1.1	-1.3	0.3	-0.7
Medication: Atenolol	0.4	0.5	2.2	0.1	-0.1	-0.4	0.0	-0.8	0.7	0.3	1.5
Medication: Levothyroxine sodium	2.2	3.7	15.1	-0.2	0.4	0.7	3.9	1.1	1.1	3.0	-1.5
Sitting height	0.8	5.5	9.6	-1.9	-2.2	-0.3	-2.5	-2.1	-2.6	-3.1	2.8
Chronic bronchitis/emphysema (father)	1.4	1.6	7.1	1.8	1.0	0.0	-1.2	-2.7	-0.3	-0.4	-0.0
High blood pressure (mother)	1.0	1.4	3.0	1.3	1.4	-0.1	-1.2	-1.4	-0.8	-1.7	0.7
Body mass index (BMI)	0.1	0.3	2.0	0.5	0.1	1.4	-0.3	-0.5	-0.0	-0.3	0.2
Impedance of leg (left)	1.5	7.3	20.2	4.3	4.5	-2.4	1.2	-2.9	2.1	0.2	-0.0
Leg predicted mass (left)	1.1	5.9	12.2	-2.8	-3.5	1.9	-2.2	-0.4	-3.2	-2.7	1.0
Trunk fat mass	0.6	2.5	7.1	0.8	0.1	0.7	-1.8	-2.7	-1.4	-2.3	1.2
Waist circumference	0.2	0.6	1.8	-0.0	-0.7	1.3	-0.9	-0.4	-0.9	-0.6	0.2
Number of incorrect matches in round	1.6	2.7	7.5	2.0	1.6	-0.3	-0.6	-2.4	-1.0	-2.7	-0.1
Past tobacco smoking	1.3	2.4	10.4	-1.7	-0.8	-3.2	-0.5	1.4	1.0	0.9	1.2
Alcohol usually taken with meals	0.7	1.1	2.4	1.4	1.6	-0.4	0.7	-0.8	1.1	-0.0	1.3
Nervous feelings	1.7	3.1	8.4	-2.0	-1.5	-2.9	0.6	2.8	-1.0	1.1	-0.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.6	-0.1	-0.6	-1.3	-0.3	-0.3	-0.3	0.7	-0.8
Hearing difficulty/problems with background noise	0.8	1.4	2.6	1.3	1.5	1.6	0.6	0.2	1.1	0.5	-1.5
Hair/balding pattern: Pattern 2	0.6	0.8	3.1	-1.2	-0.9	-1.8	-0.4	0.6	-0.1	-0.5	-0.6
Had menopause	0.6	0.8	1.6	-1.2	-1.2	-0.5	-0.6	0.3	-0.4	1.0	1.2
Had other major operations	0.6	0.7	2.7	-0.0	-0.1	-1.3	0.2	0.4	0.6	1.7	0.5
Forced vital capacity (FVC)	1.6	6.0	13.5	-1.4	-1.8	-2.6	-3.7	-1.1	-3.0	-3.5	0.1
Heel bone mineral density (BMD) T-score, automated (right)	2.8	6.4	14.4	-3.3	-3.0	-0.8	0.4	3.8	0.4	3.2	-2.3
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	4.4	1.6	1.4	0.1	2.1	-1.5	1.5	0.6	0.9
Qualifications: None of the above	0.9	2.0	4.7	-1.6	-1.9	0.2	0.4	2.1	0.5	2.2	-0.5
Financial difficulties in last 2 years	1.7	2.3	6.9	2.6	2.0	0.5	1.5	-1.9	1.0	-0.5	-0.1
Mouth/teeth dental problems	0.5	0.8	1.9	-1.4	-0.8	0.8	-0.8	1.2	-0.9	-0.4	-0.0
Heart attack	0.2	0.2	0.7	0.1	0.4	0.5	-0.4	-0.9	0.0	-0.2	0.5
Allergy	0.5	1.1	2.5	0.1	0.4	-1.3	-0.9	-1.5	-1.2	-1.6	-0.5
Pain all over the body in last month	3.0	3.2	8.9	1.1	1.3	0.3	3.0	0.8	2.2	2.9	-0.2
Diabetes (self-reported)	0.5	0.8	1.4	-0.9	-0.5	1.2	-0.4	1.0	-1.1	-0.7	-1.0
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	3.6	-0.3	-0.6	0.6	1.4	1.6	1.9	1.7	0.3
Medication: Ramipril	1.1	1.4	4.4	1.0	0.9	0.0	0.3	-0.7	1.8	1.0	2.1
Medication: Simvastatin	0.7	1.0	2.5	-0.3	-0.2	0.4	1.0	1.3	-0.5	1.6	-1.4
Fluid intelligence score	0.6	1.3	3.0	1.5	1.7	1.6	-0.2	-1.3	0.6	-0.6	-0.7
Illnesses of siblings	0.5	0.7	2.5	-0.6	-0.7	-1.6	0.2	0.4	-0.7	-0.1	-1.3
Neuroticism score	0.3	0.7	4.5	0.0	-0.1	-2.1	0.2	-0.1	-0.7	0.7	-0.4
Weight	0.5	2.7	4.8	-1.3	-2.0	1.1	-1.9	-1.0	-2.2	-2.0	1.1
Impedance of arm (right)	0.6	2.9	6.2	1.9	1.7	-1.8	-1.1	-2.4	-0.3	-2.5	0.4
Arm fat percentage (right)	0.4	1.5	3.7	1.4	0.8	1.1	-1.1	-1.9	-0.4	-1.6	0.5
Trunk fat-free mass	0.9	5.1	16.2	-3.5	-4.0	1.2	-1.3	0.9	-2.7	-1.1	0.5
Hip circumference	0.4	1.8	4.1	0.4	-0.3	2.0	-1.3	-1.7	-1.4	-1.7	0.5
Time employed in main current job	0.3	0.4	1.1	-0.3	-0.5	-0.5	-0.6	-0.9	0.2	-0.3	-1.1
Alcohol intake versus 10 years previously	0.6	0.9	4.4	0.9	0.8	0.6	2.1	0.2	0.6	0.3	-0.7
Father’s age at death	0.3	0.4	1.3	0.3	0.3	-0.5	-1.2	-0.2	-1.1	-0.5	-0.2
Worrier / anxious feelings	0.9	1.6	7.6	-0.7	-0.5	-2.8	-0.3	1.1	-0.9	0.9	-1.2
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	2.5	-0.3	-0.9	-1.3	-0.3	-0.4	0.1	0.2	-1.6
Falls in the last year	0.7	1.0	2.7	0.5	0.4	-0.1	-0.4	-1.2	-1.6	-1.0	1.4
Hair/balding pattern: Pattern 3	0.6	0.9	3.0	-0.5	-0.7	-0.8	0.6	0.2	1.7	1.0	1.2
Number of live births	2.7	3.8	7.8	2.4	2.7	1.3	2.8	0.4	1.6	1.6	-1.7
Forced expiratory volume in 1-second (FEV1)	1.5	4.9	10.2	-1.9	-2.0	-2.5	-3.2	-0.3	-2.2	-3.2	-0.3
Pulse rate	0.2	0.3	1.1	-0.3	0.1	-0.8	0.0	1.0	0.1	0.4	0.5
Happiness	1.1	1.3	7.5	0.4	0.6	0.5	2.7	0.8	0.3	0.5	-1.2
Noisy workplace	0.9	1.1	2.5	1.4	1.1	-0.1	-1.0	-1.6	0.3	-0.4	1.4
Qualifications: A levels/AS levels or equivalent	0.7	1.5	2.9	-1.5	-1.4	-0.9	0.5	1.6	-0.7	-0.7	-1.7
Serious illness, injury or assault of a close relative in last 2 years	2.1	2.4	6.0	-2.2	-1.8	-0.8	0.1	2.4	-1.6	0.9	-1.1
Mouth/teeth dental problems: Dentures	0.3	0.5	1.1	-0.7	-0.5	1.0	0.7	0.9	0.6	0.8	0.2
Asthma	0.3	0.5	1.3	0.7	0.2	-0.2	-1.1	-1.1	-0.5	-1.0	-0.2
Medication: Ibuprofen (e.g. Nurofen)	2.2	2.8	14.1	0.7	1.2	-1.1	0.4	-1.6	0.7	-1.5	3.8
Medication: Cholesterol lowering	1.0	1.6	3.0	1.7	1.7	1.2	1.6	-0.6	0.9	1.3	0.3
Depression (self-reported)	0.6	0.7	3.9	0.7	0.1	1.1	0.3	-0.1	0.1	0.3	-2.0
Medication: Lansoprazole	0.9	1.1	2.8	1.5	1.2	-0.6	-0.6	-1.7	-0.1	-0.9	0.4
Prospective memory result	1.7	2.1	6.1	-2.0	-1.8	0.4	0.4	2.5	-0.1	1.6	0.5
Lung cancer (father)	0.7	0.8	2.1	-1.0	-1.5	1.3	-0.5	1.0	-0.2	0.6	0.6
Illnesses of mother	1.2	1.5	3.2	-1.3	-1.0	-0.3	1.3	1.4	0.2	1.5	-1.8
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.4	10.0	-1.1	-1.3	-2.5	-2.0	-0.4	-1.7	-3.2	-1.0
Pulse wave Arterial Stiffness index	0.3	0.4	0.9	0.9	0.6	0.0	-0.3	-0.4	-0.7	-0.2	-1.0
Impedance of arm (left)	0.9	4.0	9.1	1.8	1.7	-2.4	-1.4	-2.8	-0.9	-3.0	0.6
Arm fat mass (right)	0.3	1.3	2.8	0.4	-0.3	1.3	-1.4	-1.5	-0.9	-1.7	0.7
Trunk predicted mass	0.9	4.9	15.7	-3.4	-4.0	1.2	-1.2	0.9	-2.6	-1.0	0.5
Standing height	1.1	11.2	22.9	-3.9	-4.6	-0.4	-3.1	-1.1	-4.8	-3.9	2.2
Length of working week for main job	0.7	0.8	1.5	1.2	1.0	-0.7	0.2	-1.2	0.1	-1.1	0.9
Exposure to tobacco smoke at home	1.8	2.0	4.2	-1.0	-1.3	0.9	1.3	2.0	0.4	1.7	-1.9
Breastfed as a baby	1.6	1.9	5.9	-2.1	-2.4	-0.0	-1.0	1.1	-0.2	0.7	1.5
Tense / ‘highly strung’	0.4	0.7	2.7	0.5	0.2	-1.4	-0.4	-0.6	-0.2	-0.1	-1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.6	3.5	1.9	1.5	0.8	0.4	-1.7	-0.8	-0.9	-1.2
Hair/balding pattern: Pattern 4	0.8	1.9	5.2	-0.2	-0.3	2.3	-0.7	1.7	-1.6	-0.4	-1.8
Birth weight of first child	0.7	1.3	4.4	-0.7	-0.6	0.7	1.7	0.9	0.9	2.1	0.3
Peak expiratory flow (PEF)	0.9	2.1	6.4	-1.9	-1.9	-2.5	-1.3	0.6	-0.1	-0.6	-0.9
Pulse wave reflection index	0.4	0.4	1.7	0.4	0.1	0.3	-0.3	-1.0	-0.5	-1.3	-0.4
Ever highly irritable/argumentative for 2 days	0.6	0.7	1.5	0.2	-0.4	-0.2	-1.2	-1.2	-0.5	-1.1	1.1
Loud music exposure frequency	0.2	0.2	0.6	-0.2	0.2	-0.2	-0.8	-0.0	0.5	-0.4	0.6
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.5	-0.4	-0.3	-1.6	-0.2	-0.4	-0.6	-1.2	0.6
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	4.6	0.8	0.3	-2.1	-0.5	-1.2	-1.5	-1.2	-0.5
Blood clot in the leg (DVT)	0.6	0.8	2.7	-0.3	-0.1	-0.0	1.0	1.7	0.7	1.2	-0.9
Medication: Paracetamol	0.4	0.6	2.4	0.4	0.1	1.1	-0.2	-0.1	0.7	0.9	-1.5
Headache pain in last month	0.5	0.8	1.6	-0.9	-0.9	1.2	0.1	1.3	-0.8	0.6	-0.7
Medication for cholesterol, blood pressure or diabetes	0.2	0.2	0.8	-0.6	-0.5	-0.5	-0.2	0.5	0.0	-0.9	-0.3
Glaucoma (self-reported)	0.6	0.7	2.9	-0.7	-0.9	1.7	-0.4	-0.1	-0.8	0.3	-0.6
Gout (self-reported)	1.2	1.6	3.4	-0.5	-0.8	0.3	-1.8	-0.8	-1.5	-1.7	1.6
Hypothyroidism/myxoedema (self-reported)	3.0	5.9	16.1	-1.2	-0.5	0.7	4.0	2.5	0.5	4.0	-2.6
Medication: Amlodipine	0.2	0.2	1.2	-0.2	-0.2	-0.3	-0.6	-0.1	0.0	0.1	1.1
Medication: Ventolin 100micrograms inhaler	1.1	1.4	3.9	1.1	0.9	0.2	1.5	-1.1	1.2	-0.4	2.0
Birth weight	1.2	2.7	8.9	-2.5	-3.0	1.4	-0.4	1.4	-1.4	0.3	-0.1
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.4	-0.4	-0.7	0.4	0.1	0.4	1.2	0.9	0.6
High blood pressure (siblings)	0.5	0.8	3.9	0.0	0.0	2.0	0.1	0.6	0.3	-0.2	1.3
Forced vital capacity (FVC), Best measure	1.2	4.4	12.3	-0.9	-1.2	-2.9	-2.5	-1.1	-2.2	-3.5	-0.2
Body fat percentage	0.6	2.5	7.7	2.3	1.7	0.7	-0.9	-2.8	0.0	-1.5	0.6
Leg fat percentage (right)	0.5	1.7	5.6	2.4	1.9	0.6	0.6	-1.6	1.0	0.2	0.1
Arm fat-free mass (right)	0.6	3.2	8.5	-2.4	-2.9	1.5	-1.3	0.0	-2.4	-1.2	0.4
Exposure to tobacco smoke outside home	0.7	0.9	3.2	-0.5	-0.7	-0.6	1.1	1.1	0.5	1.8	-0.2
Comparative body size at age 10	0.3	0.8	1.6	-0.9	-0.6	1.0	0.8	1.3	-0.2	0.9	-1.2
Number of full brothers	1.6	2.0	5.8	-1.7	-1.6	0.2	-0.1	2.4	-0.1	1.8	-1.1
Worry too long after embarrassment	0.5	0.8	4.4	0.2	0.6	-2.1	-0.2	-0.4	0.9	-0.2	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.0	0.7	0.4	-0.0	0.3	-1.0	-0.7	-0.7	-0.8
Wheeze or whistling in the chest in last year	0.2	0.3	1.2	0.9	0.2	0.2	0.0	-1.1	0.2	-0.4	0.6
Number of children fathered	0.4	0.5	2.3	0.4	0.6	-0.5	0.5	0.2	-0.6	0.4	-1.5
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.5	2.5	1.6	1.5	-0.7	0.7	-1.1	1.6	1.2	0.8
Age at first live birth	0.4	0.7	2.6	-0.2	-0.2	-0.6	-1.6	-0.2	-0.7	-1.2	-0.7
Pulse wave peak to peak time	0.5	0.5	1.8	-1.3	-1.1	-0.3	-0.0	0.5	0.3	0.1	1.0
Health satisfaction	0.9	1.1	3.5	-1.6	-1.9	-0.2	0.9	1.1	-0.5	0.3	0.6
Shortness of breath walking on level ground	0.9	1.1	3.5	-0.7	-0.4	1.2	1.4	0.7	0.6	0.6	1.9
Qualifications: College or University degree	0.7	2.3	4.6	-1.9	-1.2	1.8	-1.1	0.2	-0.7	-2.1	1.9
Eye problems/disorders: None of the above	0.2	0.3	0.7	0.3	0.2	0.1	0.8	0.5	0.5	-0.0	0.9
Mouth/teeth dental problems: Loose teeth	0.6	0.8	1.8	1.2	1.1	0.6	1.3	0.3	0.9	0.6	-0.3
Emphysema/chronic bronchitis	1.4	1.6	4.0	-1.8	-1.7	-0.5	0.1	2.0	-0.7	1.2	-0.5
Medication for pain relief, constipation, heartburn	0.3	0.6	1.6	0.4	0.3	-0.3	-0.0	-0.4	-1.2	-1.2	-1.0
Neck or shoulder pain in last month	0.6	0.8	1.6	1.1	0.7	0.4	-0.9	-1.3	-0.6	-0.4	-1.2
Medication: Blood pressure	0.1	0.2	0.8	-0.3	-0.4	0.9	-0.1	0.3	-0.0	0.6	0.7
Angina (self-reported)	0.8	1.1	2.1	1.2	1.3	1.1	0.4	-0.8	1.0	-0.3	1.5
Migraine (self-reported)	0.7	0.8	1.4	-1.0	-0.8	-1.0	0.6	1.2	-1.2	-0.7	0.6
Medication: Ibuprofen	2.1	2.6	10.3	0.5	0.7	-2.1	0.3	-1.6	1.3	-0.9	3.2
Medication: Allopurinol	0.4	0.5	2.2	0.3	0.2	-0.9	-0.1	-0.9	0.0	-0.7	1.5
Medication: Omeprazole	1.8	2.2	4.4	1.7	1.6	0.5	1.3	-0.9	2.1	2.0	-0.9
Medication: Seretide 50 evohaler	0.4	0.5	1.3	0.7	0.2	0.6	-0.5	-1.1	0.3	-0.9	0.9
Mean time to correctly identify matches	1.1	2.1	6.9	-1.5	-1.5	-0.6	-0.7	1.6	-2.6	-0.2	-1.5
Heart disease (mother)	1.1	1.4	3.6	1.4	1.4	0.3	-0.9	-1.9	0.4	-0.8	1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.5	0.9	0.6	-0.6	-0.6	-1.2	1.1	-0.7	0.2
Whole body fat mass	0.4	1.7	4.4	0.8	0.1	1.1	-1.3	-2.1	-1.0	-1.9	0.8
Leg fat mass (right)	0.3	1.0	3.1	0.9	0.3	1.1	-0.7	-1.8	-0.6	-1.3	0.6
Arm predicted mass (right)	0.7	3.3	8.3	-2.5	-2.9	1.5	-1.4	0.1	-2.5	-1.2	0.6
Pulse rate, automated reading	0.4	1.3	3.0	-1.7	-1.7	-1.2	-0.6	0.8	-1.4	-0.6	-0.6
Alcohol intake frequency.	0.2	0.4	1.0	-1.0	-1.0	-0.2	-0.3	-0.3	-0.2	-0.3	0.9
Comparative height size at age 10	1.0	5.7	15.5	-3.5	-3.9	0.8	-1.3	1.1	-3.6	-1.1	-0.1
Number of full sisters	0.5	0.6	2.9	0.5	0.7	-0.6	-0.5	-0.1	0.1	-0.6	-1.7
Suffer from ‘nerves’	0.9	1.5	6.7	-1.4	-1.2	-2.6	-0.6	0.3	-1.1	0.0	0.2
Overall health rating	0.5	1.0	5.7	-0.2	-0.6	0.2	0.6	0.7	-0.9	0.2	-2.4
Chest pain or discomfort	0.1	0.2	0.4	-0.2	0.0	-0.5	0.4	0.6	-0.1	-0.3	-0.5
Had major operations	1.7	2.0	6.6	0.9	0.9	-0.7	-0.4	-2.6	-1.2	-2.1	1.1
Age at last live birth	0.3	0.4	1.1	-0.6	-0.3	0.4	-0.9	0.4	-1.1	-0.6	-0.5
Family relationship satisfaction	1.6	1.9	6.9	1.4	1.5	2.6	1.4	-1.1	0.3	-1.0	-0.1
Leg pain on walking	0.6	0.7	2.1	0.1	0.1	-1.5	-1.4	-1.0	-0.3	-0.7	0.1
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.6	4.6	1.9	2.1	-1.3	0.3	-1.6	0.7	0.1	0.4
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.1	1.4	1.5	1.3	-0.3	-0.4	-0.4	1.0	-0.1
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.9	-0.1	0.1	0.9	-0.1	-0.6	0.8	-0.2	0.7
Medication: Aspirin	0.4	0.5	2.1	-0.8	-0.6	0.6	-0.4	0.7	-0.0	1.5	0.0
Supplements: Vitamin C	0.3	0.3	1.2	0.4	0.4	0.1	-0.8	-1.1	-0.1	0.1	-0.5
Knee pain experienced in last month	0.8	1.3	4.0	-0.2	-0.8	-1.0	-2.0	-0.9	-1.1	-0.9	-1.4
Hypertension (Self-reported)	0.2	0.6	1.6	-1.1	-1.0	0.4	-0.6	1.3	0.0	0.9	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	3.7	1.5	1.7	-0.3	-1.1	-1.9	-0.1	-0.8	0.9
Illnesses of father: Heart disease	2.1	2.9	6.4	1.3	1.4	-0.5	-2.3	-2.1	-1.5	-2.5	1.2
Illnesses of siblings: Diabetes	1.0	1.2	3.1	-1.8	-1.4	0.9	0.3	1.5	-0.0	1.2	-0.1
Smoking status: Previous	1.9	2.8	11.2	2.0	1.3	3.3	0.4	-1.9	-0.8	-1.1	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	3.4	-0.4	-0.8	0.2	-0.3	-1.1	-1.8	-1.4	0.6
Whole body fat-free mass	1.0	5.7	15.1	-3.2	-3.9	1.7	-1.8	0.3	-3.1	-1.8	0.8
Leg fat-free mass (right)	1.2	6.6	13.2	-2.9	-3.6	2.0	-2.6	-0.3	-3.4	-2.8	1.0
Arm fat percentage (left)	0.5	1.9	5.0	1.5	0.9	0.7	-1.4	-2.2	-0.6	-2.0	0.2
Average weekly red wine intake	0.5	0.7	1.8	1.0	1.3	0.5	0.7	-0.9	-0.8	-0.5	0.4
Handedness (chirality/laterality): Left-handed	0.6	0.8	1.9	-1.4	-0.7	-1.0	-1.0	1.2	-0.5	-0.1	0.1
Mood swings	1.2	2.1	4.5	1.4	1.1	-1.4	-0.4	-2.1	-1.6	-1.7	-1.2
Loneliness, isolation	0.6	0.8	2.1	1.3	1.0	1.1	0.5	-1.5	-0.3	-0.4	0.5
Long-standing illness, disability or infirmity	0.9	1.4	3.7	-0.5	-0.8	-1.1	-1.5	-0.8	-1.9	-1.5	-0.8
Ever had bowel cancer screening	0.5	0.6	2.5	-0.3	-0.1	-0.1	-1.6	0.4	-1.1	-0.2	-0.6
Diabetes diagnosed by doctor	0.5	0.8	3.2	-0.3	-0.1	1.8	0.1	0.6	-0.8	-0.5	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	2.5	1.6	1.3	1.0	0.7	0.0	1.4	1.1	-1.1
Friendships satisfaction	2.0	2.5	7.1	2.1	2.7	1.1	2.2	0.1	1.3	0.4	-0.8
Qualifications: nursing, teaching	0.5	0.9	2.2	-1.5	-1.5	0.3	-0.2	0.6	-0.9	-0.0	-1.1
Commuting to job workplace: Walk	0.3	0.3	1.4	0.2	-0.0	-0.2	-0.2	-0.7	-0.3	-1.2	0.6
Eye problems/disorders: Cataract	0.2	0.2	0.8	0.3	0.5	-0.7	-0.4	-0.3	0.3	0.4	-0.9
Mouth/teeth dental problems: Mouth ulcers	1.2	2.0	5.4	2.2	1.4	-1.0	0.7	-2.3	1.3	0.8	0.1
Medication for cholesterol	0.1	0.2	0.5	0.4	0.2	0.5	0.3	0.3	-0.7	0.2	-0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	0.8	-0.3	0.0	0.9	0.4	0.4	-0.2	-0.1	0.7
Back pain experienced in last month	0.6	0.9	2.6	-0.6	-1.0	-1.1	-0.9	-0.4	0.8	1.6	-1.0
Mineral and other dietary supplements	1.1	1.5	7.1	1.0	1.3	0.3	2.7	1.0	1.0	0.0	0.0
Breast cancer (self-reported)	1.5	1.8	6.8	0.0	0.1	0.1	2.6	2.0	1.4	1.0	0.4
Asthma (self-reported)	0.3	0.6	1.7	0.8	0.4	-0.3	-1.0	-1.3	-0.5	-1.1	-0.1
Osteoporosis (self-reported)	0.9	1.1	2.3	1.2	1.5	-1.4	0.6	-0.2	1.1	1.0	0.7
Osteoarthritis (self-reported)	0.4	0.6	0.8	-0.7	-0.9	0.9	-0.3	0.8	-0.6	0.9	-0.8
Medication: Aspirin	0.6	0.8	3.3	-1.0	-0.7	0.3	-0.1	1.1	0.4	1.8	0.1
Medication: Gliclazide	0.2	0.2	0.6	-0.6	-0.3	0.4	0.4	0.6	-0.5	0.2	-0.8
Illnesses of father: None of the above (group 1)	1.6	2.0	4.4	-1.8	-1.9	0.5	1.5	2.1	-0.3	1.3	-0.5
Smoking status: Current	0.6	1.0	2.0	-0.9	-1.3	0.7	0.3	1.1	-1.2	-0.6	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	9.0	-1.1	-0.9	-3.0	-1.3	0.5	-0.1	-0.4	-1.0
Whole body water mass	1.0	6.0	15.9	-3.3	-4.0	1.8	-1.8	0.4	-3.2	-1.8	0.8
Leg predicted mass (right)	1.2	6.6	13.4	-2.9	-3.7	2.1	-2.6	-0.2	-3.4	-2.8	1.0
Arm fat mass (left)	0.4	1.5	3.8	0.5	-0.2	1.0	-1.4	-1.8	-1.1	-1.9	0.7
Number of self-reported non-cancer illnesses	0.2	0.4	1.7	0.7	0.5	-0.2	0.1	-0.6	-0.5	1.3	-0.2
Average weekly champagne plus white wine intake	0.8	1.1	2.6	1.1	1.1	1.6	0.6	-0.3	1.1	-1.4	0.3
Miserableness	0.6	1.1	2.3	1.5	1.4	0.3	0.1	-1.3	-0.5	-1.4	-0.9
Guilty feelings	0.3	0.4	1.0	0.1	-0.0	-1.0	-0.7	-0.3	-0.8	1.0	-0.2
Wears glasses or contact lenses	1.6	1.8	8.0	-1.1	-0.9	1.1	0.7	0.7	0.0	1.5	2.8
Ever taken oral contraceptive pill	0.6	0.7	3.8	0.3	-0.0	2.0	0.2	-0.6	-1.0	-0.3	0.1
Hearing aid user	1.4	1.6	3.3	-1.8	-1.5	-0.7	0.7	1.4	1.0	1.8	0.5
Mother’s age at death	0.8	1.0	2.7	-0.7	-1.4	0.3	-1.6	0.2	-0.9	-1.1	1.0
Financial situation satisfaction	2.8	3.5	13.8	2.2	2.2	1.1	3.7	-0.3	1.6	0.4	-0.6
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.5	-0.3	-0.7	1.2	0.3	0.6	0.2	0.1	0.1
Commuting to job workplace: Public transport	3.1	3.7	12.2	-3.5	-3.5	-0.3	-1.0	1.9	-0.5	-0.2	0.5
Eye problems/disorders: Glaucoma	1.3	1.5	4.3	-1.3	-1.5	2.1	0.2	1.1	0.0	1.4	-1.0
Medication: Blood pressure	0.3	0.6	1.9	-1.0	-0.9	-1.4	-0.6	0.2	0.9	0.4	0.4
Pain type(s) experienced in last month: Hip pain	0.9	1.2	6.1	0.7	0.4	-2.5	-0.8	-1.3	0.3	-0.3	-0.0
Supplements: Fish oil (including cod liver oil)	0.9	1.1	3.1	-1.2	-1.5	0.1	-1.8	0.3	-1.2	0.2	-0.8
High cholesterol (Self-reported)	0.4	0.8	1.8	1.2	0.5	1.1	0.7	-0.8	-0.1	0.3	-1.3
Medication: Bendroflumethiazide	0.8	1.2	3.2	-1.8	-1.8	-0.7	-0.4	1.5	-0.0	0.5	0.2
Medication: Paracetamol	0.5	0.7	2.3	-0.1	-0.3	-0.0	0.1	0.6	0.9	1.4	-1.5
Medication: Lisinopril	1.4	1.8	8.9	-0.5	-1.0	3.0	-0.2	-0.0	-1.2	-1.2	1.2
Medication: Atorvastatin	0.5	0.6	2.0	-0.1	-0.5	1.3	0.5	0.1	0.9	-0.4	1.4
Illnesses of father: High blood pressure	0.6	0.7	2.6	-1.2	-0.9	-0.6	-0.1	1.6	-0.6	0.3	0.2
Alcohol drinker status: Never	0.9	1.0	3.0	-0.2	0.7	0.5	1.7	1.0	1.5	1.1	-0.2
Ever smoked	0.9	1.6	4.7	1.4	0.5	1.9	-0.0	-0.9	-0.7	-0.8	-2.2
Basal metabolic rate	0.8	4.7	11.0	-2.6	-3.3	1.7	-1.9	-0.1	-2.8	-2.0	0.9
Leg fat percentage (left)	0.6	2.1	6.8	2.6	2.1	0.7	0.3	-1.9	1.1	-0.0	0.3
Arm fat-free mass (left)	0.5	2.6	7.3	-2.1	-2.7	2.0	-0.9	0.2	-1.8	-0.7	0.6
Number of operations (self-reported)	1.1	1.6	5.0	1.6	1.5	0.0	2.2	-0.7	-0.4	1.7	-0.2
Average weekly beer plus cider intake	0.8	1.2	3.9	-0.2	-0.4	0.2	-1.4	-0.4	-2.0	-1.8	-0.1
Irritability	0.3	0.6	2.7	0.8	0.2	-0.5	0.1	-0.8	-0.4	0.5	-1.6
Risk taking	1.0	1.5	3.5	1.3	1.4	1.2	-0.1	-1.8	-0.1	-1.9	0.2
Ever had prostate specific antigen (PSA) test	1.2	1.4	3.3	-1.0	-1.1	-1.5	-0.4	1.5	-1.1	0.4	-1.8
Fractured/broken bones in last 5 years	0.8	1.1	5.7	-0.8	-0.7	0.7	-0.5	0.6	-2.4	-0.5	-0.5
Age started oral contraceptive pill	0.4	0.5	2.2	-0.4	-0.4	0.2	-0.3	-0.3	-0.4	-0.9	1.5
Diastolic blood pressure, automated reading	0.2	0.6	2.0	0.7	0.6	0.5	0.7	0.4	0.9	1.4	-0.8
Ever depressed for a whole week	1.3	1.6	5.7	0.6	0.7	0.9	2.4	0.9	1.7	1.5	-0.2
Unable to work because of sickness or disability	0.2	0.3	0.9	0.4	0.2	0.6	0.9	-0.2	-0.2	0.3	-0.6
Commuting to job workplace: Cycle	0.2	0.2	1.3	-0.4	-0.1	-0.0	0.3	0.1	-0.2	-1.1	-0.1
Myopia	0.1	0.1	0.4	0.1	-0.3	0.4	0.2	-0.1	-0.6	-0.1	0.3
Vascular/heart problems diagnosed by doctor	0.1	0.3	1.2	0.5	0.4	-0.4	0.1	-0.7	-0.4	-1.1	-0.0
Cholesterol lowering medication	0.7	1.0	2.3	-0.9	-1.2	1.5	0.4	1.2	0.3	0.8	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.7	0.9	0.9	-0.4	0.4	-0.7	1.6	0.7	0.2
Pain experienced in last month	0.5	0.9	3.1	-0.1	0.3	0.0	1.6	0.4	0.8	-0.5	1.8
Supplements: Calcium	0.3	0.3	0.9	-0.4	0.1	0.3	0.8	0.3	0.7	1.0	-0.0
Basal cell carcinoma (self-reported)	0.9	1.0	1.9	-1.1	-1.4	-0.0	0.8	1.2	-1.4	-0.0	-1.1
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.9	0.1	0.4	0.4	-0.4	-1.0	0.1	-0.1	0.5
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	3.2	-0.3	-0.1	-0.0	1.4	1.8	1.0	1.8	-0.9
Heart disease (siblings)	1.5	1.9	5.4	2.3	2.3	1.1	0.6	-1.6	0.6	-0.2	0.2
Alcohol drinker status: Previous	0.3	0.3	1.4	-0.0	0.1	0.1	0.2	-0.0	0.7	0.5	1.2
Pack years of smoking	0.2	0.3	0.9	0.9	0.6	0.2	0.9	-0.0	0.5	0.1	-0.1
Impedance of whole body	1.1	5.6	12.6	3.5	3.5	-2.3	-0.0	-3.2	1.0	-1.7	0.7
Leg fat mass (left)	0.3	1.2	3.7	1.1	0.5	1.2	-0.7	-1.9	-0.4	-1.4	0.6
Arm predicted mass (left)	0.6	3.1	8.8	-2.5	-3.0	2.2	-0.9	0.5	-1.6	-0.8	1.0