Hub : Genes

SLC22A23

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1280	0.0400	7.7e-04	-0.003	NA	0.027	NA	0.006	6.6e-01	NA	2.8e-03	NA	9.0e-02
2	GTEx	Artery Aorta	0.2380	0.0810	3.4e-03	-0.005	NA	-0.005	NA	-0.002	9.4e-01	NA	9.7e-01	NA	4.3e-01
3	GTEx	Esophagus Muscularis	0.2040	0.0660	2.4e-03	0.000	NA	-0.004	NA	-0.001	3.4e-01	NA	7.8e-01	NA	3.7e-01
4	METSIM	Adipose	0.0746	0.0246	7.5e-04	-0.002	0.025	0.009	0.022	-0.002	7.1e-01	9.9e-05	1.4e-02	2.4e-04	9.6e-01
5	NTR	Blood	0.0216	0.0086	5.9e-03	0.000	0.002	-0.001	0.002	-0.001	2.5e-01	4.3e-02	8.6e-01	6.3e-02	7.6e-01
6	ROSMAP	Brain Pre-frontal Cortex	0.2088	0.0359	4.2e-15	0.135	0.161	0.154	0.163	0.131	5.1e-17	3.9e-20	2.8e-19	1.8e-20	1.8e-16
7	TCGA	Brain Lower Grade Glioma	0.0465	0.0216	3.6e-03	0.043	0.017	0.014	NA	0.029	1.1e-05	4.4e-03	9.6e-03	NA	2.9e-04
8	TCGA	Prostate Adenocarcinoma	0.0696	0.0376	9.9e-03	0.038	0.015	0.016	NA	0.026	7.4e-05	8.9e-03	7.2e-03	NA	9.2e-04

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Bipolar Disorder (2018)	0.4	0.6	3.1	-0.4	0.6	0.4	-0.3	0.7	1.8	0.6	-0.5
Bipolar Disorder or Schizophrenia	0.5	1.2	8.0	0.2	0.6	-0.3	0.5	0.4	2.8	0.7	-0.8
Depressed Affect (Nagel 2018)	1.1	2.4	8.5	-0.6	-2.3	-2.9	0.7	-1.8	-0.7	0.2	-0.8
Depression (Nagel 2018)	0.9	1.3	5.5	1.3	-2.3	-1.2	-0.9	-0.4	-0.0	0.2	-1.1
Intelligence (Savage-Jansen 2018)	1.0	3.1	10.2	-0.2	3.1	3.2	1.0	1.1	1.2	-0.5	0.9
Neuroticism (Nagel 2018)	0.4	1.0	4.0	-0.1	-0.7	-2.0	1.5	-0.9	-0.1	-0.8	0.0
Schizophrenia (2018)	0.4	0.9	4.9	0.7	0.3	-0.7	1.0	-0.1	2.2	0.4	-0.6
Schizophrenia vs Biploar Disorder	0.1	0.1	0.4	0.3	0.0	0.2	0.6	0.1	0.4	-0.4	0.6
Worry (Nagel 2018)	0.2	0.4	1.5	-0.1	0.0	-1.2	1.0	-0.0	0.6	-0.6	0.3
Alzheimer’s Disease (in mother)	0.9	1.0	3.8	0.7	0.4	1.0	0.5	-0.3	-0.1	1.5	-1.9
Alzheimer’s Disease (in father)	2.2	2.4	5.7	0.0	1.6	2.4	0.8	2.4	1.8	-0.9	0.8
Alzheimer’s Disease (including proxy)	0.5	0.7	2.9	0.4	0.5	1.7	0.3	0.6	0.1	0.8	-1.1
Crohns Disease (2017)	2.1	4.6	9.2	2.7	3.0	0.9	-0.7	1.9	1.0	2.6	-2.8
Irritable Bowel Disease (IBD)	1.0	2.3	4.8	2.2	2.1	0.1	-1.3	0.7	0.2	1.8	-1.8
Ulcerative Colitis (UC)	0.3	0.5	1.5	0.8	0.6	-0.5	-1.2	-0.7	-0.5	0.6	-0.5
Major Depression (MDD)	0.1	0.1	0.3	0.3	-0.0	-0.2	-0.3	-0.5	-0.4	0.4	-0.6
Reaction Time	0.4	0.7	1.8	0.2	1.3	-1.1	0.0	-0.8	-0.9	-0.8	0.8
Verbal and Numeric Reasoning (VNR)	0.8	1.8	5.7	-0.6	2.3	2.4	-0.2	0.4	1.4	1.0	-0.6
Breast Cancer	0.6	1.4	3.7	-0.7	-0.9	-0.6	1.0	0.6	1.1	-1.9	1.9
Ovarian Cancer	0.1	0.1	0.3	-0.2	-0.0	-0.1	0.0	0.3	-0.6	0.4	-0.5
Prostate Cancer	0.3	0.4	1.8	-0.4	-0.7	-0.5	0.3	-1.3	-0.5	0.4	-0.3
Age at First Birth	0.7	1.0	3.1	-1.6	0.9	0.8	-0.8	0.0	-1.8	0.2	0.1
Bipolar Disorder (2011)	0.3	0.3	1.5	-0.0	0.0	-0.8	-0.6	-0.4	1.2	-0.3	0.1
Body Mass Index (BMI) (2010)	2.1	2.8	10.0	1.5	-1.4	-0.6	1.9	0.8	3.2	1.5	-1.2
Coronary Artery Disease (CAD)	1.7	2.0	4.8	1.3	-1.7	-1.5	1.2	-2.2	-1.0	-1.3	0.8
Crohns Disease (2012)	2.6	4.1	10.3	2.3	3.2	1.4	-0.6	1.7	2.2	1.9	-1.9
Mean Putamen Volume	1.1	1.2	3.1	0.9	1.8	0.2	-1.4	1.3	0.9	0.8	-0.9
Fasting Glucose	2.3	2.8	7.1	1.6	0.3	-1.8	-1.2	-0.8	-1.0	2.7	-2.5
HbA1C	1.2	1.3	4.5	2.1	-1.7	-0.3	-0.1	0.8	1.5	-0.5	0.2
HDL Cholesterol	1.0	1.7	5.0	0.1	1.1	2.2	2.2	0.4	-0.4	-1.3	0.9
LDL Cholesterol	0.3	0.5	2.7	0.3	0.3	-0.5	-1.6	0.1	0.7	0.6	-0.4
Lupus	1.2	1.9	4.6	0.6	1.0	1.8	0.6	-0.1	0.7	2.1	-2.1
Neuroticism (2016)	0.5	0.8	3.3	-0.0	-0.2	-1.2	-0.1	-1.8	-0.8	0.5	-0.8
Primary Biliary Cirrhosis	1.7	2.5	7.9	-1.0	0.6	1.3	1.0	0.6	0.3	-2.7	2.8
Rheumatoid Arthritis	0.8	1.1	2.4	-0.3	0.9	1.0	0.3	0.8	1.4	1.5	-1.5
Schizophrenia (2014)	0.9	2.0	9.1	0.9	1.8	-0.6	1.3	0.1	3.0	0.4	-0.6
Triglycerides	0.4	0.7	4.6	0.1	-2.1	-0.6	-0.6	-0.1	0.0	-0.5	0.4
Type 2 Diabetes (T2D) (2012)	1.9	2.2	5.9	2.4	-0.7	-0.9	0.5	0.2	1.0	2.0	-2.2
Ulcerative Colitis	0.3	0.4	1.6	0.7	0.4	1.3	-0.8	-0.1	-0.6	0.4	-0.2
Blood Eosinophil Count	0.2	1.4	4.1	1.3	0.1	-0.3	0.9	-1.3	0.5	2.0	-1.7
Blood Platelet Count	0.4	4.6	7.8	0.7	2.8	2.4	-1.6	1.8	-1.8	2.8	-2.5
Blood Red Count	0.5	4.8	11.8	-0.9	-1.7	-1.2	3.4	2.5	1.6	-2.5	2.5
Blood White Count	0.3	2.1	6.7	2.0	-2.6	-1.4	0.4	-1.2	1.2	0.9	-0.7
Heel T-Score	0.1	0.9	3.2	1.8	0.1	0.1	-0.7	-0.2	0.3	1.0	-1.4
BMI	0.4	2.2	7.3	1.8	-2.7	-2.0	-0.5	-1.0	0.5	0.6	-0.9
Height	0.0	0.9	3.0	1.6	0.6	0.2	-0.5	0.2	1.7	0.9	-0.3
Waist Hip Ratio (WHR)	0.5	2.3	4.5	0.6	-1.7	-2.1	-0.4	-2.1	-0.6	1.8	-1.7
Systolic Blood Pressure	0.2	0.9	3.1	0.2	1.1	1.0	-1.1	1.8	-0.0	-0.5	-0.0
Smoking Status	1.0	2.4	5.5	2.3	-0.9	-0.9	-0.1	-1.4	0.6	2.2	-2.3
Allergy or Eczema	0.4	1.0	2.4	0.6	1.6	1.0	-1.0	0.5	0.2	1.4	-0.9
Cardiovascular Disease	0.1	0.3	1.3	0.3	-1.1	-0.1	0.2	0.6	0.6	0.1	-0.3
Hypothyroidism (self reported)	0.2	0.5	1.3	0.6	-1.1	-0.3	1.1	-0.8	0.6	-0.4	0.1
Respiratory disease	0.3	0.6	1.8	0.6	1.3	0.8	-1.1	-0.0	0.2	0.3	-1.0
Type 2 Diabetes (T2D) (2018)	0.7	1.3	4.7	-0.5	-0.9	-0.7	2.0	-2.2	-0.6	-0.2	0.2
Lung FEV1/FVC ratio	0.4	2.1	4.8	2.2	-0.6	0.9	2.1	1.1	2.0	0.4	-0.7
Lung FVC	0.6	3.2	7.9	0.0	-2.1	-2.7	-1.6	-2.8	-0.8	1.5	-0.6
Neuroticism	0.5	1.2	5.8	-0.2	-0.2	-2.4	0.5	-1.4	-1.3	-0.3	-0.2
Chronotype (morning person)	1.4	3.1	10.3	-0.2	-2.1	-0.2	0.9	0.5	3.2	-2.0	2.3
Hair Pigment	0.4	11.0	34.3	1.1	-5.9	-5.8	-1.3	-4.0	0.5	0.9	-0.1
Tanning	0.1	1.6	3.0	0.9	1.0	1.7	-0.1	1.7	-1.0	0.9	-1.7
Hand grip strength (left)	1.8	4.7	20.1	0.1	4.5	1.2	-3.4	1.7	1.2	0.0	0.2
Number of treatments/medications taken	1.4	2.5	5.7	2.4	0.7	0.5	0.3	0.9	1.7	2.1	-2.3
Average weekly spirits intake	0.6	0.7	2.4	0.9	-1.5	-0.9	-0.6	0.0	-0.2	0.8	-0.8
Sensitivity / hurt feelings	0.8	1.3	4.3	-0.7	0.7	-0.9	0.1	-1.1	-2.1	1.1	-1.4
Frequency of depressed mood in last 2 weeks	1.2	1.7	4.3	0.2	-1.8	-1.6	-1.4	-1.1	-2.1	0.2	-0.7
Hearing difficulty/problems: Yes	1.1	1.7	5.1	0.1	-1.6	-2.3	-0.1	-2.2	-0.2	-0.8	0.7
Relative age of first facial hair	0.5	1.0	2.8	-0.4	-0.7	1.7	-0.4	-1.5	-1.5	0.3	-0.2
Other serious medical condition/disability diagnosed by doctor	1.3	1.6	5.8	1.5	0.3	1.0	0.7	-0.3	-0.6	1.7	-2.4
Ever used hormone-replacement therapy (HRT)	0.7	0.9	3.1	1.0	-0.2	1.0	0.1	-0.1	0.0	1.5	-1.8
Ever had hysterectomy (womb removed)	1.7	1.9	5.0	0.4	2.2	0.5	-0.7	0.2	0.2	2.2	-2.1
Systolic blood pressure, automated reading	0.3	0.8	1.5	1.2	-0.9	0.5	-0.7	0.6	-1.1	0.5	-1.1
Eye problems/disorders: Diabetes related eye disease	0.6	0.7	2.5	-0.4	-1.6	0.4	1.5	0.3	0.4	0.4	-0.4
Angina	1.4	1.8	6.5	0.9	0.2	0.4	-1.7	-0.5	-0.0	2.5	-2.0
Medication for hormone replacement therapy	1.3	1.5	4.0	1.7	1.1	-0.6	-0.9	0.3	2.0	1.3	-0.9
Vitamin and mineral supplements	1.4	1.9	8.3	-1.5	-2.9	-0.9	-1.0	-1.2	-0.8	0.4	-0.5
Supplements: Zinc	0.4	0.5	1.9	1.2	1.4	-0.1	-0.5	0.3	0.3	-0.4	0.3
Medication: Co-codamol	2.1	2.5	5.9	1.3	-1.7	0.6	1.2	-1.3	1.0	2.4	-2.2
Medication: Metformin	0.3	0.4	1.4	0.7	-0.4	-0.5	0.1	-1.0	-1.2	-0.2	0.1
Diabetes (father)	0.4	0.5	1.1	0.3	0.9	0.9	1.1	0.1	-0.1	-0.7	0.6
Diabetes (mother)	0.7	0.8	2.1	1.1	-0.2	-1.5	-0.0	-0.8	0.1	1.1	-1.2
Severe depression (siblings)	0.3	0.3	1.3	1.2	0.2	0.8	0.0	-0.2	0.3	0.3	-0.4
Pack years adult smoking proportion	2.0	3.1	8.7	2.9	0.9	-2.0	-1.1	-0.2	0.7	2.1	-2.4
Impedance of leg (right)	0.1	0.3	1.1	0.9	0.1	-1.1	0.2	0.2	0.5	0.3	-0.2
Leg fat-free mass (left)	0.0	0.2	0.6	-0.0	-0.2	0.6	-0.1	-0.4	-0.1	-0.4	0.8
Trunk fat percentage	0.8	3.0	6.2	2.5	-2.4	-1.8	1.8	-1.8	0.5	0.9	-1.3
Hand grip strength (right)	1.4	3.9	11.9	-1.1	3.3	0.8	-3.4	1.8	0.4	-1.0	1.2
Townsend deprivation index at recruitment	1.4	2.0	6.1	1.1	-1.6	-1.4	0.4	-2.5	-0.5	1.4	-1.3
Current tobacco smoking	2.0	3.3	8.0	2.1	0.1	-1.4	-1.7	-1.2	-0.2	2.8	-2.8
Average weekly fortified wine intake	0.3	0.4	1.5	-1.2	0.1	0.4	0.9	-0.2	-0.0	0.4	-0.6
Maternal smoking around birth	0.8	1.1	2.6	1.2	-0.8	-1.5	-0.4	-0.0	1.6	1.0	-0.8
Fed-up feelings	1.4	2.5	5.4	0.4	-1.9	-2.3	0.1	-1.7	-0.3	1.8	-2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.3	5.7	0.6	-2.4	-1.2	-0.2	-1.5	-0.0	0.2	-0.7
Relative age voice broke	0.8	1.3	2.6	0.1	1.5	1.4	-0.5	-0.6	-0.2	1.6	-1.6
Taking other prescription medications	1.0	1.6	5.5	1.0	-1.4	-0.4	1.7	-2.3	-0.3	0.8	-0.8
Age when periods started (menarche)	0.5	1.2	2.6	0.5	1.6	0.6	0.3	1.3	1.2	1.1	-1.2
Bilateral oophorectomy (both ovaries removed)	0.7	0.9	3.0	0.1	0.1	-0.6	-0.5	-0.2	0.6	1.7	-1.7
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.8	0.1	-0.3	-0.9	1.4	-0.2	1.0	0.3	0.1
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	6.5	2.5	-0.0	-0.7	0.3	-0.3	0.8	0.3	-0.2
Qualifications: CSEs or equivalent	1.2	1.6	6.0	0.0	-2.1	-0.7	2.4	0.5	0.4	-1.0	0.8
Serious illness, injury or assault to yourself	0.9	1.1	3.0	0.9	0.4	1.6	0.6	-1.7	-0.2	0.7	-1.0
High blood pressure	0.6	1.6	5.3	0.8	-0.6	-1.2	-1.1	0.0	0.2	2.0	-2.3
Hayfever, allergic rhinitis or eczema	0.8	1.8	3.7	0.5	1.4	1.4	-1.9	-0.1	-1.0	1.8	-1.5
Multivitamins +/- minerals	0.9	1.2	7.1	1.4	2.7	0.1	0.1	-0.2	-0.2	0.3	-0.2
Stomach or abdominal pain in last month	1.1	1.3	3.2	0.7	-1.0	-1.7	-0.0	-0.8	0.0	1.6	-1.8
Supplements: Glucosamine	1.5	1.9	5.0	1.1	-0.5	2.2	1.1	2.0	1.9	-0.0	0.3
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	1.9	-0.8	-0.2	1.0	0.9	0.9	1.1	1.4	-0.9
Medication: Atenolol	0.4	0.5	1.6	-0.7	0.4	-0.1	-0.2	0.1	0.2	1.3	-1.3
Medication: Levothyroxine sodium	0.9	1.5	3.4	0.8	-1.8	-0.7	-0.2	-1.5	-0.2	1.6	-1.8
Sitting height	0.4	3.0	7.5	-1.1	2.4	2.7	0.6	0.5	0.7	-1.6	2.3
Chronic bronchitis/emphysema (father)	0.6	0.7	1.7	0.9	-0.9	-0.0	-0.1	0.5	1.3	1.1	-1.0
High blood pressure (mother)	0.8	1.1	2.4	-0.7	0.1	-0.0	-0.2	1.3	-1.6	-1.5	1.4
Body mass index (BMI)	0.4	1.8	4.5	2.0	-2.1	-1.6	0.7	-1.4	-0.1	0.6	-1.0
Impedance of leg (left)	0.1	0.7	1.9	1.4	0.1	-0.6	0.2	0.6	1.2	0.7	-0.9
Leg predicted mass (left)	0.0	0.2	0.7	-0.1	-0.2	0.5	-0.1	-0.4	-0.1	-0.5	0.8
Trunk fat mass	0.5	2.3	5.8	2.4	-2.1	-1.5	1.2	-1.5	0.7	0.8	-1.1
Waist circumference	0.8	3.0	8.7	1.9	-3.0	-1.4	1.0	-2.3	-0.3	1.1	-1.3
Number of incorrect matches in round	2.9	4.9	11.5	-0.4	-3.4	-3.0	1.9	0.0	0.6	-2.7	2.7
Past tobacco smoking	0.5	0.9	3.1	-1.8	0.4	0.4	-1.1	0.2	-1.4	-0.5	0.8
Alcohol usually taken with meals	1.0	1.6	5.0	-1.8	1.5	2.2	-0.7	1.1	0.2	-0.4	0.5
Nervous feelings	0.5	0.9	2.1	-0.8	-1.0	-1.2	1.4	-0.6	-1.0	-0.7	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.0	-0.1	-1.0	-0.5	-0.2	-0.0	0.5	-0.1	-0.0
Hearing difficulty/problems with background noise	0.7	1.0	2.8	0.9	-0.4	-1.7	0.3	-1.4	0.8	-0.9	1.0
Hair/balding pattern: Pattern 2	1.1	1.4	8.1	-2.8	0.4	0.2	0.1	0.1	-1.3	-0.8	0.9
Had menopause	1.8	2.2	5.1	1.6	0.3	1.6	1.6	1.2	2.3	1.4	-1.4
Had other major operations	2.3	2.8	5.9	-1.2	2.4	2.0	-2.3	1.4	0.3	1.3	-1.3
Forced vital capacity (FVC)	0.3	1.2	4.6	-1.1	0.3	-1.1	-0.9	-0.4	0.5	-1.2	2.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.6	0.9	0.2	0.0	1.3	0.6	1.1	0.4	-0.4
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.9	0.1	0.0	-1.4	-1.0	0.1	0.5	0.8	-0.8
Qualifications: None of the above	1.8	3.8	11.2	3.3	-2.6	-2.1	-0.3	-1.2	1.9	1.1	-1.2
Financial difficulties in last 2 years	1.0	1.3	3.6	0.8	-1.6	-1.0	0.6	-1.9	-0.1	1.0	-1.2
Mouth/teeth dental problems	0.4	0.7	2.2	-0.8	1.5	0.6	-0.7	0.7	-0.7	-0.6	0.8
Heart attack	0.4	0.5	2.5	0.7	0.4	0.2	1.6	-0.4	0.4	0.4	-0.4
Allergy	0.8	1.9	3.4	-0.6	-1.2	-1.5	1.9	0.5	1.5	-1.6	1.5
Pain all over the body in last month	1.0	1.0	2.7	1.2	-0.5	0.2	-1.0	-0.1	0.3	1.6	-1.6
Diabetes (self-reported)	0.5	0.8	2.6	0.7	-0.9	-1.2	1.6	-0.9	0.1	0.0	-0.3
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.2	1.5	1.0	0.2	0.3	1.3	1.3	-0.5	0.8
Medication: Ramipril	0.4	0.5	2.4	-0.7	0.1	-0.0	0.0	-1.1	-1.5	0.3	-0.3
Medication: Simvastatin	0.3	0.5	1.9	-0.3	1.1	0.7	1.4	-0.0	-0.6	0.3	-0.3
Fluid intelligence score	0.9	1.8	8.6	-0.4	2.9	1.7	-0.4	0.9	0.8	-0.4	0.7
Illnesses of siblings	0.6	0.8	4.4	-2.1	-0.6	0.7	0.8	0.4	0.6	-0.0	0.2
Neuroticism score	0.6	1.3	5.8	-0.3	-0.6	-2.4	0.2	-1.3	-0.8	0.8	-1.2
Weight	0.2	1.0	2.8	1.7	-1.5	-0.5	0.8	-1.2	0.7	0.3	-0.3
Impedance of arm (right)	0.3	1.5	6.4	-1.1	-0.1	-0.9	2.5	-1.2	-0.1	-1.1	1.1
Arm fat percentage (right)	0.8	3.2	7.1	1.6	-2.3	-2.7	1.7	-2.3	-0.2	0.8	-1.2
Trunk fat-free mass	0.1	0.3	1.7	0.1	0.4	0.2	-1.3	0.0	0.1	-0.2	0.6
Hip circumference	0.2	0.7	2.6	0.8	-1.0	0.1	1.0	-1.6	-0.3	-0.1	0.1
Time employed in main current job	1.8	2.1	4.3	1.5	1.7	-0.6	-1.3	-1.7	-0.7	1.5	-2.1
Alcohol intake versus 10 years previously	2.5	3.7	14.0	3.7	-0.7	-2.6	0.6	-0.9	1.5	1.7	-1.5
Father’s age at death	0.8	1.1	3.2	-1.8	1.2	1.0	-0.6	0.4	-1.3	0.7	-0.8
Worrier / anxious feelings	0.4	0.7	2.6	-0.1	-1.0	-1.6	0.5	-0.1	0.9	0.5	-0.6
Frequency of tiredness / lethargy in last 2 weeks	1.3	2.2	11.8	1.0	-3.4	-1.0	0.3	-1.0	0.3	1.1	-1.1
Falls in the last year	1.8	2.4	8.1	2.9	-1.0	0.7	-0.5	-0.1	2.0	1.7	-1.6
Hair/balding pattern: Pattern 3	0.6	1.0	3.7	1.9	-0.3	-0.1	0.8	-0.3	0.5	1.0	-1.4
Number of live births	0.5	0.8	2.1	-0.2	-0.7	-0.2	1.0	1.5	-0.2	-1.2	1.0
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	3.4	-1.5	0.2	-0.4	-0.5	-0.1	0.4	-1.1	1.9
Pulse rate	0.1	0.2	0.5	0.6	-0.7	-0.6	-0.0	-0.6	0.4	-0.2	0.4
Happiness	0.9	1.1	4.3	-0.8	-0.1	-0.3	-0.9	1.5	-2.1	0.5	-0.6
Noisy workplace	0.4	0.5	2.0	0.1	-0.4	-1.4	-0.8	-0.5	-0.0	0.4	-0.6
Qualifications: A levels/AS levels or equivalent	2.4	5.2	13.3	-2.1	3.5	3.6	-1.2	1.8	0.1	-1.5	2.2
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	2.4	-1.0	0.2	0.8	-1.6	-1.1	-1.0	-0.6	0.4
Mouth/teeth dental problems: Dentures	0.5	0.8	2.5	1.6	-0.0	-0.8	-0.0	-0.4	0.1	1.1	-1.3
Asthma	0.4	0.7	2.5	0.1	1.4	1.6	-1.0	0.3	-0.4	-0.2	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	2.5	0.8	1.0	1.5	-0.2	1.6	-0.2	0.6	-0.4
Medication: Cholesterol lowering	0.9	1.4	3.9	1.0	1.4	-0.8	-0.2	-0.8	-0.6	2.0	-1.6
Depression (self-reported)	0.5	0.7	1.4	-0.8	-0.9	-1.2	1.1	-0.9	-0.5	-0.0	0.3
Medication: Lansoprazole	0.6	0.6	2.5	-0.7	-1.6	0.6	0.8	0.8	0.4	0.3	-0.5
Prospective memory result	2.0	2.4	8.2	-0.6	-2.9	-2.3	0.2	-1.8	-1.1	-0.8	0.4
Lung cancer (father)	1.5	1.7	5.3	1.0	-1.6	0.2	0.4	-0.8	0.8	1.9	-2.3
Illnesses of mother	0.4	0.4	1.4	-0.9	0.7	0.5	-0.3	-1.2	0.0	-0.5	0.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	1.7	-0.7	0.4	1.2	-0.5	0.8	0.5	-0.6	1.3
Pulse wave Arterial Stiffness index	0.6	0.7	2.9	0.4	0.9	-0.4	0.2	0.1	0.6	1.7	-1.2
Impedance of arm (left)	0.4	1.7	4.2	-1.9	-0.2	-0.3	2.1	-1.2	-0.7	-1.4	1.4
Arm fat mass (right)	0.5	2.0	4.9	1.5	-2.2	-1.9	1.0	-1.8	-0.2	0.5	-0.9
Trunk predicted mass	0.1	0.3	1.6	0.1	0.4	0.2	-1.3	-0.0	0.1	-0.2	0.7
Standing height	0.2	1.5	4.3	-0.6	1.5	2.1	-0.1	0.4	1.5	-0.8	1.5
Length of working week for main job	0.4	0.4	2.1	1.5	-0.0	-0.4	0.3	-0.0	0.4	-0.3	0.8
Exposure to tobacco smoke at home	3.3	3.7	8.5	1.4	0.1	-2.6	-1.6	-2.9	-1.2	1.8	-2.2
Breastfed as a baby	1.6	2.0	7.5	0.8	1.0	1.1	-1.6	2.7	0.2	1.2	-1.3
Tense / ‘highly strung’	0.6	1.0	4.8	-0.1	-0.6	-2.2	0.9	-1.0	0.9	-0.2	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	4.1	-0.2	-1.9	-0.2	1.6	-0.0	2.0	-0.5	0.3
Hair/balding pattern: Pattern 4	0.5	1.1	2.4	-0.3	-1.5	-1.0	-0.4	-0.1	1.2	-1.2	1.6
Birth weight of first child	0.3	0.5	1.6	1.3	-0.9	-0.6	-0.2	-0.3	1.0	0.1	0.3
Peak expiratory flow (PEF)	0.6	1.5	3.0	-0.8	1.7	1.7	-0.8	1.1	0.1	-1.1	1.4
Pulse wave reflection index	0.5	0.6	2.6	-0.5	1.6	0.7	0.4	-0.1	0.8	0.9	-0.3
Ever highly irritable/argumentative for 2 days	2.7	3.2	9.5	3.1	0.7	0.6	1.2	1.6	2.9	0.9	-1.5
Loud music exposure frequency	0.2	0.2	0.4	-0.3	-0.4	-0.7	-0.2	0.1	0.6	-0.5	0.6
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	3.6	-1.5	1.5	0.8	-0.2	0.2	-0.7	-1.3	1.9
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.8	-0.5	-1.3	0.7	0.6	0.3	0.7	-0.2	0.4
Blood clot in the leg (DVT)	1.2	1.6	3.6	1.6	-0.1	1.5	-0.3	-0.6	0.7	1.8	-1.9
Medication: Paracetamol	0.6	1.0	1.7	1.1	-1.1	1.0	0.1	-1.0	0.7	1.3	-1.0
Headache pain in last month	1.0	1.7	5.6	1.5	1.4	1.1	-0.3	1.3	2.4	0.7	-0.7
Medication for cholesterol, blood pressure or diabetes	1.1	1.9	5.1	-1.2	-1.2	1.4	0.3	0.4	-0.1	-2.2	2.3
Glaucoma (self-reported)	0.3	0.3	0.5	0.6	0.3	0.7	0.3	0.3	0.7	0.7	-0.6
Gout (self-reported)	0.8	1.1	2.3	-0.3	-1.5	0.6	0.3	-0.7	-1.2	-1.1	1.5
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.4	1.6	-0.5	-0.5	0.6	-1.4	-0.2	0.8	-1.1
Medication: Amlodipine	1.0	1.4	4.9	-2.2	-1.2	-1.0	-0.7	-0.6	-1.2	-0.8	1.0
Medication: Ventolin 100micrograms inhaler	0.3	0.4	0.8	0.6	-0.3	0.9	-0.6	-0.6	-0.9	0.3	-0.6
Birth weight	0.5	1.1	3.3	-1.6	-0.6	-0.5	-1.8	-0.9	-0.4	-0.4	1.0
Chronic bronchitis/emphysema (mother)	1.5	1.7	4.1	2.0	-0.6	-0.9	-1.5	-0.4	1.4	1.6	-1.3
High blood pressure (siblings)	0.6	0.9	1.6	1.0	0.1	-1.3	-1.2	-1.3	-1.1	-0.3	0.3
Forced vital capacity (FVC), Best measure	0.1	0.5	1.5	-0.4	0.6	0.5	-1.2	0.2	0.1	-0.4	1.2
Body fat percentage	0.9	3.6	7.3	2.6	-2.7	-2.2	1.5	-1.9	0.4	1.1	-1.7
Leg fat percentage (right)	1.1	3.9	8.5	2.8	-2.9	-2.6	0.8	-1.6	0.5	1.2	-1.6
Arm fat-free mass (right)	0.1	0.6	1.8	0.8	0.4	1.3	-1.3	0.7	0.4	0.0	0.2
Exposure to tobacco smoke outside home	1.3	1.7	9.8	0.1	-0.8	-3.1	0.2	-0.3	1.8	0.2	-0.1
Comparative body size at age 10	0.3	0.9	2.7	0.5	1.6	1.3	0.6	0.9	0.7	0.7	-0.6
Number of full brothers	1.3	1.6	4.8	1.4	0.7	0.5	-2.2	1.1	1.7	1.0	-0.5
Worry too long after embarrassment	0.6	1.0	2.8	0.5	1.7	0.2	1.4	1.0	-0.4	0.8	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	6.1	0.4	0.5	-1.6	0.5	0.1	2.5	0.1	0.3
Wheeze or whistling in the chest in last year	1.9	3.3	9.3	1.0	-0.6	-0.9	-2.0	-2.0	-0.6	2.6	-3.1
Number of children fathered	1.5	1.7	3.7	-0.1	0.5	1.4	1.4	1.9	0.9	-1.6	1.4
Reason for reducing amount of alcohol drunk: Health precaution	1.6	1.8	12.7	0.1	3.6	0.5	0.8	0.3	0.7	-0.4	0.5
Age at first live birth	0.7	1.2	3.6	-1.9	-0.1	0.2	-1.0	-1.0	-1.7	-0.5	0.8
Pulse wave peak to peak time	0.5	0.6	2.6	-0.4	-0.7	0.4	-0.2	-0.2	-0.5	-1.6	1.1
Health satisfaction	0.2	0.3	1.1	0.5	0.1	0.6	-0.1	1.1	-0.5	0.2	-0.4
Shortness of breath walking on level ground	0.5	0.6	3.0	1.7	-0.2	-0.8	-0.3	-0.7	0.1	0.4	-0.2
Qualifications: College or University degree	1.9	5.9	17.6	-3.3	4.2	3.2	-0.6	1.3	-0.9	-1.6	1.5
Eye problems/disorders: None of the above	0.3	0.4	1.0	-0.9	1.0	0.2	-0.5	0.3	0.4	-0.7	0.5
Mouth/teeth dental problems: Loose teeth	0.9	1.1	3.8	0.3	-1.2	1.9	0.5	0.6	0.2	1.0	-1.5
Emphysema/chronic bronchitis	0.3	0.3	1.1	-0.2	-0.8	1.1	-0.2	0.2	-0.7	0.1	-0.5
Medication for pain relief, constipation, heartburn	1.5	2.5	7.0	-1.9	0.9	-1.1	-0.5	0.7	-0.7	-2.6	2.5
Neck or shoulder pain in last month	0.7	1.0	3.7	0.6	-0.8	0.5	-0.8	1.4	1.9	0.8	-0.0
Medication: Blood pressure	0.9	1.5	5.1	0.3	1.6	-0.7	-0.2	-0.5	-0.0	1.9	-2.3
Angina (self-reported)	1.0	1.3	4.4	0.5	-0.2	0.2	-1.3	-0.9	-0.3	2.1	-1.6
Migraine (self-reported)	0.5	0.6	1.6	-0.1	-0.0	0.8	0.9	1.3	0.7	-0.9	0.6
Medication: Ibuprofen	1.2	1.4	4.5	1.0	1.2	2.1	-0.5	1.5	-0.4	0.9	-0.8
Medication: Allopurinol	2.0	2.7	8.9	-0.5	-0.9	-0.0	-0.2	-3.0	-2.9	-1.2	1.4
Medication: Omeprazole	1.9	2.2	5.1	2.3	-0.2	0.1	0.7	-0.9	1.5	2.1	-2.2
Medication: Seretide 50 evohaler	0.4	0.5	2.4	-0.4	-0.0	0.7	-1.6	0.1	0.2	0.5	-0.7
Mean time to correctly identify matches	0.3	0.6	2.3	0.0	0.0	-1.5	0.7	-1.4	-0.6	-0.1	-0.0
Heart disease (mother)	1.0	1.2	4.1	-0.6	-1.6	-2.0	-0.1	-0.4	-1.4	-0.2	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	2.6	-1.6	0.5	0.6	-1.0	0.2	-1.1	-0.8	0.7
Whole body fat mass	0.6	2.5	5.6	2.4	-2.3	-1.7	1.0	-1.5	0.4	0.9	-1.3
Leg fat mass (right)	0.7	2.6	6.2	2.4	-2.5	-1.8	0.4	-1.3	0.5	1.2	-1.4
Arm predicted mass (right)	0.1	0.7	1.7	1.2	0.3	1.2	-1.3	0.7	0.6	0.1	0.2
Pulse rate, automated reading	0.3	0.9	3.3	1.0	-1.8	-1.1	0.2	-1.1	-0.4	-0.2	0.1
Alcohol intake frequency.	0.7	1.7	3.3	1.8	-1.5	-1.7	1.2	-1.5	0.4	0.7	-0.9
Comparative height size at age 10	0.2	1.0	5.7	1.0	-0.3	0.3	0.6	-0.6	2.4	0.5	0.3
Number of full sisters	0.7	0.8	2.5	0.9	1.1	0.3	-0.5	0.0	0.2	1.3	-1.6
Suffer from ‘nerves’	0.1	0.1	0.5	0.2	-0.1	-0.7	0.5	-0.4	0.0	-0.0	0.1
Overall health rating	1.5	3.2	10.2	2.0	-1.6	-0.4	0.3	-0.9	-0.5	2.7	-3.2
Chest pain or discomfort	1.7	2.5	5.8	0.8	0.8	0.6	-2.3	-1.4	-0.3	2.2	-2.4
Had major operations	0.6	0.7	1.4	-0.6	-0.7	-0.7	0.7	1.1	1.2	-0.9	0.7
Age at last live birth	1.4	2.1	7.0	-2.6	-1.4	-0.2	-1.0	-1.1	-2.1	-0.4	1.0
Family relationship satisfaction	2.6	3.3	10.6	-0.1	1.5	-0.3	-3.2	0.7	-3.2	1.2	-1.0
Leg pain on walking	1.8	2.2	5.0	1.9	-1.2	-2.2	0.5	-0.6	1.4	1.6	-1.6
Qualifications: NVQ or HND or HNC or equivalent	1.5	1.8	11.6	0.1	-0.8	-3.4	0.1	-1.2	-0.6	-0.6	0.5
Commuting to job workplace: Car/motor vehicle	2.3	2.6	6.0	0.1	-1.8	-1.3	2.4	-1.4	0.2	-1.9	2.0
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.7	0.2	0.3	-0.8	0.3	0.5	0.2	-0.0	0.5
Medication: Aspirin	1.3	1.8	5.6	1.3	0.0	1.2	0.3	0.3	0.5	2.2	-2.4
Supplements: Vitamin C	1.3	1.6	4.0	0.2	0.4	2.0	1.2	1.6	1.0	-1.3	1.4
Knee pain experienced in last month	1.0	1.5	4.4	1.3	-2.1	0.9	1.7	-0.3	1.5	0.2	-0.3
Hypertension (Self-reported)	0.3	0.9	3.1	0.7	-0.5	-0.8	-0.7	0.3	0.4	1.4	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.0	-0.0	-1.0	0.6	0.2	-0.2	0.9	-0.5	0.7
Illnesses of father: Heart disease	0.4	0.6	2.8	0.1	-1.0	0.3	1.7	0.2	-0.3	-0.6	0.4
Illnesses of siblings: Diabetes	0.4	0.4	1.5	0.3	-0.6	-0.4	1.1	-1.2	-0.0	-0.4	-0.0
Smoking status: Previous	0.2	0.4	1.1	0.8	-0.3	0.1	0.9	0.4	1.0	-0.3	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	3.9	-0.2	0.9	0.6	-0.7	0.3	0.2	-1.7	2.0
Whole body fat-free mass	0.0	0.2	0.9	0.2	0.1	0.5	-0.9	0.0	0.1	-0.2	0.6
Leg fat-free mass (right)	0.0	0.2	0.9	-0.0	0.1	0.9	-0.2	-0.1	0.2	-0.4	0.7
Arm fat percentage (left)	0.6	2.6	5.3	1.4	-2.3	-2.3	1.6	-2.1	-0.3	0.4	-0.9
Average weekly red wine intake	1.4	2.0	6.3	-0.8	2.5	1.7	-1.0	1.7	0.8	1.1	-0.7
Handedness (chirality/laterality): Left-handed	1.3	1.6	4.8	2.2	0.2	-0.4	-0.1	-0.7	2.0	1.5	-1.2
Mood swings	2.3	4.1	14.3	-0.7	-3.8	-3.5	0.6	-2.1	-0.5	0.1	-0.4
Loneliness, isolation	0.6	0.8	2.9	0.7	-0.3	-0.8	-0.4	-0.5	-0.3	1.4	-1.7
Long-standing illness, disability or infirmity	1.4	2.1	5.3	2.2	0.3	-0.2	1.0	-1.2	0.3	2.1	-2.3
Ever had bowel cancer screening	1.1	1.3	4.7	2.2	-1.0	-0.7	0.5	-0.4	0.8	0.9	-1.6
Diabetes diagnosed by doctor	0.6	1.0	2.8	0.0	-0.7	-1.4	1.6	-1.7	-0.5	-0.3	-0.0
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.8	0.4	-0.9	-0.4	-0.9	0.4	0.6	0.7	-0.5
Friendships satisfaction	0.4	0.5	2.8	-0.8	0.1	-0.1	-0.3	0.2	-1.7	0.3	-0.4
Qualifications: nursing, teaching	2.3	3.6	13.2	-1.7	2.8	3.6	-1.8	1.3	-0.3	-0.1	0.5
Commuting to job workplace: Walk	0.9	1.0	2.7	0.9	0.2	1.2	-0.2	1.6	1.6	-0.3	-0.1
Eye problems/disorders: Cataract	0.6	0.7	2.3	1.4	-1.5	-1.1	0.2	0.2	-0.1	0.2	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.6	0.1	-0.1	-0.5	-0.3	-0.7	0.5	0.2	0.1
Medication for cholesterol	0.3	0.5	1.6	-1.3	-0.0	0.5	0.7	0.3	-0.9	-0.7	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.4	1.6	7.1	1.0	-0.6	1.2	0.0	2.7	1.0	1.0	-1.1
Back pain experienced in last month	1.5	2.2	6.7	1.7	-1.5	0.1	0.1	2.0	2.6	0.8	-1.0
Mineral and other dietary supplements	1.8	2.4	7.0	-1.8	-0.6	-2.6	-0.4	-1.9	-2.1	-0.1	-0.0
Breast cancer (self-reported)	1.3	1.5	3.3	0.3	1.4	0.6	-0.9	1.2	1.6	1.8	-1.3
Asthma (self-reported)	0.3	0.6	2.1	0.1	1.3	1.4	-0.9	0.2	-0.5	-0.2	0.0
Osteoporosis (self-reported)	0.6	0.7	3.1	1.8	-0.0	0.6	0.5	0.5	1.4	0.1	-0.1
Osteoarthritis (self-reported)	0.9	1.1	4.7	-0.0	-2.2	1.1	1.3	0.7	0.3	0.4	-0.6
Medication: Aspirin	1.4	1.8	6.1	1.4	0.1	0.8	0.2	-0.1	0.7	2.3	-2.5
Medication: Gliclazide	1.3	1.4	3.3	0.8	-1.5	-1.5	1.1	-1.8	-1.0	0.5	-0.7
Illnesses of father: None of the above (group 1)	0.8	1.0	3.9	-1.1	-0.7	-2.0	-0.6	-1.1	-0.5	-0.4	0.6
Smoking status: Current	1.9	3.1	6.8	2.6	-0.1	-1.4	-0.9	-1.4	0.1	2.5	-2.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	2.5	0.6	-0.1	0.1	-0.6	-0.6	-0.0	1.6	-0.9
Whole body water mass	0.0	0.2	0.9	0.2	0.2	0.5	-0.9	0.1	0.2	-0.2	0.7
Leg predicted mass (right)	0.1	0.3	1.1	-0.1	0.2	1.1	-0.1	0.0	0.2	-0.5	0.8
Arm fat mass (left)	0.5	1.9	4.2	1.9	-2.1	-1.9	0.8	-1.6	-0.1	0.5	-0.8
Number of self-reported non-cancer illnesses	0.4	0.7	2.4	0.6	-0.4	0.2	0.8	0.1	1.0	1.0	-1.5
Average weekly champagne plus white wine intake	1.4	2.0	6.2	-1.4	-0.6	0.1	-0.7	0.5	-0.7	-2.4	2.5
Miserableness	1.3	2.3	5.4	-0.4	-2.1	-2.3	1.6	-2.1	0.2	0.6	-0.8
Guilty feelings	0.2	0.3	1.3	-0.4	0.1	-1.1	-0.1	-0.4	-0.6	-0.2	-0.2
Wears glasses or contact lenses	1.6	1.9	3.5	-1.3	-1.8	1.3	1.9	-0.7	-0.7	-1.4	1.4
Ever taken oral contraceptive pill	0.8	0.9	2.2	-0.2	1.5	-0.9	0.4	-0.4	-0.4	1.0	-1.5
Hearing aid user	2.5	2.8	6.4	0.1	-1.9	-0.8	1.3	-0.5	2.2	-2.2	2.5
Mother’s age at death	1.0	1.3	2.3	-1.5	1.1	1.3	-0.2	1.3	1.2	-0.6	1.2
Financial situation satisfaction	0.2	0.2	0.9	0.3	0.1	-0.4	0.7	0.3	-1.0	-0.5	0.1
Tinnitus: Yes, now most or all of the time	0.4	0.4	1.4	0.8	-0.8	0.0	0.6	-0.6	-1.2	0.0	-0.4
Commuting to job workplace: Public transport	1.3	1.5	4.9	0.9	1.7	0.0	-2.2	-0.4	-0.1	1.4	-1.2
Eye problems/disorders: Glaucoma	0.1	0.1	0.3	0.4	0.5	0.6	0.2	-0.1	0.2	0.4	-0.3
Medication: Blood pressure	0.1	0.2	0.6	0.5	-0.6	-0.4	-0.4	0.0	0.8	-0.1	-0.2
Pain type(s) experienced in last month: Hip pain	1.3	1.6	3.7	0.8	0.2	-1.5	1.9	0.2	1.9	0.8	-1.4
Supplements: Fish oil (including cod liver oil)	1.2	1.6	4.1	1.7	0.7	2.0	0.7	1.2	1.6	0.7	-0.6
High cholesterol (Self-reported)	0.4	0.7	2.1	-0.0	-1.4	-0.6	1.4	-0.1	0.7	-0.6	0.6
Medication: Bendroflumethiazide	0.3	0.4	1.4	1.0	-0.3	0.1	-0.2	-0.5	0.7	0.7	-1.2
Medication: Paracetamol	0.5	0.7	2.3	1.4	-0.2	1.5	0.5	-0.5	0.8	0.5	-0.5
Medication: Lisinopril	0.9	1.1	3.2	1.8	1.2	-1.3	0.8	-0.6	0.9	0.4	-1.0
Medication: Atorvastatin	0.8	0.9	1.9	0.9	0.7	-1.4	-0.7	-0.4	1.4	1.0	-0.8
Illnesses of father: High blood pressure	1.1	1.4	4.5	-0.0	0.9	2.1	-0.4	1.9	-1.1	-0.5	0.6
Alcohol drinker status: Never	1.5	1.8	6.9	0.5	-2.1	-0.8	0.7	-2.6	1.1	-0.2	0.4
Ever smoked	0.5	0.8	2.9	1.3	0.2	-1.0	0.0	0.0	1.7	0.7	-0.8
Basal metabolic rate	0.0	0.1	0.5	0.5	-0.3	0.2	-0.7	-0.3	0.1	0.0	0.3
Leg fat percentage (left)	1.2	4.2	9.4	3.1	-2.9	-2.4	1.1	-1.4	1.0	1.4	-2.0
Arm fat-free mass (left)	0.1	0.4	1.5	1.2	-0.3	0.3	-0.9	0.2	0.6	0.2	0.1
Number of operations (self-reported)	0.5	0.7	1.6	-0.8	1.0	1.1	-0.0	1.3	0.7	0.6	-0.4
Average weekly beer plus cider intake	1.1	1.6	5.0	0.9	-2.2	-2.1	0.1	-0.1	-0.9	0.8	-1.1
Irritability	0.9	1.5	4.2	1.3	0.1	-1.5	-0.6	-2.0	-0.9	1.0	-1.3
Risk taking	1.2	1.8	2.9	1.0	0.6	-0.9	-1.6	1.5	1.7	1.7	-1.3
Ever had prostate specific antigen (PSA) test	0.9	1.1	5.5	-0.1	0.8	-2.3	-0.0	-1.0	0.3	-0.9	0.5
Fractured/broken bones in last 5 years	1.3	1.6	3.6	1.6	1.0	0.4	-1.3	-0.7	0.7	1.7	-1.9
Age started oral contraceptive pill	0.6	0.7	1.5	-0.8	1.1	1.2	0.7	0.9	0.3	0.7	-0.8
Diastolic blood pressure, automated reading	0.5	1.6	3.8	1.9	-1.4	-0.8	-1.1	0.2	-0.0	1.5	-1.8
Ever depressed for a whole week	0.4	0.5	2.5	0.6	-0.6	-1.6	0.4	-0.3	0.1	-0.5	0.4
Unable to work because of sickness or disability	2.0	2.6	5.3	2.3	-1.9	-1.5	0.5	-0.4	0.4	2.1	-2.3
Commuting to job workplace: Cycle	1.0	1.3	5.3	0.1	1.3	0.5	-2.3	-0.5	-1.0	1.0	-0.8
Myopia	0.8	1.2	2.9	-1.0	1.4	0.7	0.4	-0.4	-0.2	-1.7	1.6
Vascular/heart problems diagnosed by doctor	0.5	1.5	4.2	-1.4	0.1	0.6	0.2	-0.1	-1.3	-1.9	2.1
Cholesterol lowering medication	0.6	0.9	2.9	0.3	-0.7	1.1	1.7	0.7	1.2	-0.7	0.7
Medication: Omeprazole (e.g. Zanprol)	1.8	2.2	6.1	1.8	-0.8	-0.1	0.0	-1.5	0.6	2.3	-2.5
Pain experienced in last month	0.9	1.6	6.4	-1.6	0.9	0.0	-0.2	-1.3	-2.5	-0.9	0.6
Supplements: Calcium	0.6	0.7	1.3	0.9	1.0	1.1	0.2	0.8	0.9	0.7	-0.4
Basal cell carcinoma (self-reported)	0.6	0.7	1.2	-0.3	-0.0	-1.0	0.9	-0.9	-0.5	-1.0	1.1
Heart attack/myocardial infarction (self-reported)	0.3	0.4	2.4	0.6	0.4	0.2	1.6	-0.1	0.5	0.1	-0.1
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	3.6	1.3	-0.0	1.9	-0.3	-0.5	0.4	1.6	-1.6
Heart disease (siblings)	1.2	1.5	5.4	2.3	1.4	0.3	-0.3	1.0	1.6	0.7	-0.7
Alcohol drinker status: Previous	0.2	0.2	0.6	-0.4	-0.2	-0.8	-0.1	-0.4	0.5	-0.6	0.2
Pack years of smoking	1.9	2.7	8.8	3.0	0.8	-1.6	-0.8	-0.1	0.7	1.9	-2.3
Impedance of whole body	0.1	0.3	2.0	-0.3	0.1	-0.1	1.4	-0.1	0.4	-0.6	0.5
Leg fat mass (left)	0.7	2.6	6.4	2.5	-2.4	-1.6	0.6	-1.1	0.8	1.2	-1.5
Arm predicted mass (left)	0.1	0.4	1.4	1.2	-0.0	0.6	-1.1	0.3	0.6	0.3	0.0