TWAS hub - SLC25A10

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Lung Squamous Cell Carcinoma	0.0256	0.0149	7e-04	0.020	0.022	0.026	NA	0.023	0.00230	1.3e-03	5.1e-04	NA	1.1e-03
2	TCGA	Thyroid Carcinoma	0.0600	0.0350	1e-05	0.035	0.058	0.054	NA	0.050	0.00025	2.3e-06	5.7e-06	NA	1.1e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Hair Pigment	13.0	371.4	571.2	-23.9	-13.1
Exposure to tobacco smoke outside home	7.1	9.5	10.0	3.0	3.2
Myopia	7.1	10.3	11.4	-3.4	-3.0
Lung cancer (father)	6.9	8.1	8.4	2.9	2.8
Hearing aid user	6.0	6.8	9.6	-2.0	-3.1
Breast cancer (self-reported)	5.9	7.0	8.0	-2.5	-2.8
Bilateral oophorectomy (both ovaries removed)	5.2	6.0	6.2	2.5	2.4
Blood Red Count	5.1	49.1	49.6	7.0	7.0
Eye problems/disorders: Cataract	5.0	5.8	10.6	-3.3	-1.0
Depression (Nagel 2018)	4.7	7.0	7.3	2.7	2.6
Hearing difficulty/problems: Yes	4.7	7.1	7.6	-2.6	-2.8
Loneliness, isolation	4.6	6.3	6.9	2.6	2.4
Knee pain experienced in last month	4.5	7.1	7.1	2.7	2.7
Basal cell carcinoma (self-reported)	4.3	5.2	7.2	2.7	1.8
Ever had hysterectomy (womb removed)	4.1	4.6	4.8	2.2	2.1
Long-standing illness, disability or infirmity	3.4	5.2	5.7	-2.4	-2.2
Relative age voice broke	3.3	5.1	8.5	1.3	2.9
Mean Putamen Volume	3.2	3.7	4.4	-1.7	-2.1
Illnesses of father: High blood pressure	3.2	4.0	4.5	-2.1	-1.8
Frequency of unenthusiasm / disinterest in last 2 weeks	3.1	4.2	4.2	2.0	2.0
Ever highly irritable/argumentative for 2 days	3.1	3.7	4.5	-1.7	-2.1
Taking other prescription medications	2.9	4.5	4.6	-2.1	-2.1
Gout (self-reported)	2.9	3.9	5.5	-2.3	-1.5
Number of full sisters	2.8	3.4	4.3	-1.6	-2.1
Medication for cholesterol, blood pressure or diabetes	2.7	4.6	4.8	2.1	2.2
Breast Cancer	2.6	6.3	6.9	2.4	2.6
Illness, injury, bereavement, stress in last 2 years	2.6	3.1	3.8	-1.9	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.6	3.0	3.1	-1.8	-1.7
Medication: Levothyroxine sodium	2.5	4.2	4.5	-2.1	-2.0
Leg fat percentage (right)	2.5	9.1	11.0	3.3	2.7
Chest pain or discomfort	2.5	3.7	4.2	-1.8	-2.1
Leg fat percentage (left)	2.5	9.0	10.7	3.3	2.7
Risk taking	2.4	3.4	4.5	-2.1	-1.6
Relative age of first facial hair	2.3	4.7	7.5	1.4	2.7
Hypothyroidism/myxoedema (self-reported)	2.3	4.5	5.1	-2.0	-2.3
Ever taken oral contraceptive pill	2.3	2.6	3.8	2.0	1.2
Tanning	2.2	26.4	39.3	6.3	3.7
Ever unenthusiastic/disinterested for a whole week	2.1	2.5	4.0	-1.0	-2.0
Time employed in main current job	2.1	2.4	2.5	1.5	1.6
Alcohol drinker status: Never	2.1	2.5	2.6	-1.6	-1.5
Fluid intelligence score	2.0	4.2	6.0	2.5	1.5
Vascular/heart problems diagnosed by doctor	2.0	5.6	6.7	2.6	2.1
Number of treatments/medications taken	1.9	3.3	3.4	-1.8	-1.9
Length of working week for main job	1.9	2.1	2.2	-1.5	-1.4
Body fat percentage	1.9	7.3	7.5	2.7	2.7
Medication: Aspirin	1.8	2.4	2.4	-1.5	-1.6
Type 2 Diabetes (T2D) (2018)	1.7	3.2	4.3	1.4	2.1
Angina	1.7	2.2	4.2	-2.1	-0.5
Number of children fathered	1.7	1.9	2.6	1.6	1.1
Angina (self-reported)	1.7	2.2	4.2	-2.0	-0.5
Number of self-reported non-cancer illnesses	1.7	2.9	4.4	-2.1	-1.2
Intelligence (Savage-Jansen 2018)	1.6	4.8	6.8	2.6	1.7
Trunk fat percentage	1.6	6.5	6.9	2.5	2.6
Average weekly fortified wine intake	1.6	1.9	3.1	1.7	0.8
Hayfever, allergic rhinitis or eczema	1.6	3.4	4.6	2.1	1.5
Diverticular disease/diverticulitis (self-reported)	1.6	1.9	2.0	1.3	1.4
Waist circumference	1.6	5.7	6.0	2.5	2.3
Medication: Blood pressure	1.6	2.9	3.4	-1.5	-1.9
Medication: Aspirin	1.6	2.2	2.4	-1.5	-1.4
Heel T-Score	1.5	12.1	15.2	3.9	3.0
Trunk fat mass	1.5	6.3	6.5	2.5	2.6
Hip circumference	1.5	6.7	6.8	2.5	2.6
Leg fat mass (right)	1.5	5.7	6.2	2.5	2.3
Leg fat mass (left)	1.5	5.8	5.9	2.4	2.4
High blood pressure	1.4	3.9	5.0	-2.2	-1.7
High blood pressure (mother)	1.4	1.9	3.2	-0.8	-1.8
Health satisfaction	1.4	1.8	2.2	-1.5	-1.2
Wheeze or whistling in the chest in last year	1.3	2.3	2.7	-1.6	-1.4
Eye problems/disorders: None of the above	1.3	1.5	2.9	1.7	-0.1
Whole body fat mass	1.3	5.3	5.4	2.3	2.3
Hypertension (Self-reported)	1.3	3.5	4.3	-2.1	-1.7
Bipolar Disorder or Schizophrenia	1.2	2.8	3.8	-1.3	-2.0
Neuroticism (2016)	1.2	1.7	2.6	-0.9	-1.6
Cardiovascular Disease	1.2	3.9	4.2	-2.0	-1.9
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	3.0	-1.7	-0.0
Shortness of breath walking on level ground	1.2	1.5	1.9	-1.4	-1.0
Arm fat percentage (left)	1.2	4.7	4.8	2.1	2.2
Medication: Atorvastatin	1.2	1.5	2.0	1.4	1.0
Frequency of depressed mood in last 2 weeks	1.1	1.5	2.2	1.5	0.9
Ever used hormone-replacement therapy (HRT)	1.1	1.4	1.6	1.3	1.1
Financial difficulties in last 2 years	1.1	1.5	2.3	1.5	0.9
Arm fat percentage (right)	1.1	4.2	4.3	2.0	2.1
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	2.4	1.0	1.6
Qualifications: A levels/AS levels or equivalent	1.1	2.4	4.4	-0.7	-2.1
Birth weight	1.1	2.3	2.9	-1.3	-1.7
Osteoarthritis (self-reported)	1.1	1.4	2.5	0.5	1.6
Medication: Bendroflumethiazide	1.1	1.7	2.0	-1.2	-1.4
Schizophrenia (2018)	1.0	2.1	3.0	-1.0	-1.7
Verbal and Numeric Reasoning (VNR)	1.0	2.3	4.1	2.0	0.7
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	2.1	-0.7	-1.5
Number of live births	1.0	1.4	2.6	1.6	0.5
Headache pain in last month	1.0	1.6	2.4	-0.9	-1.5
Medication: Amlodipine	1.0	1.4	1.4	-1.2	-1.2
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	1.8	1.3	0.8
Commuting to job workplace: Cycle	1.0	1.2	1.2	1.1	1.1
Worry too long after embarrassment	0.9	1.5	1.6	-1.3	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	1.4	-1.2	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	1.2	0.9	1.1
Neck or shoulder pain in last month	0.9	1.2	1.9	0.7	1.4
Medication for cholesterol	0.9	1.3	2.5	1.6	0.5
Osteoporosis (self-reported)	0.9	1.1	2.0	-0.4	-1.4
Arm fat mass (left)	0.9	3.5	3.7	1.8	1.9
Pain experienced in last month	0.9	1.5	2.0	-1.4	-1.0
Hypothyroidism (self reported)	0.8	1.7	2.7	-0.9	-1.6
Impedance of leg (left)	0.8	3.8	5.9	2.4	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.3	2.2	0.5	1.5
Medication: Ramipril	0.8	1.1	1.6	-1.3	-0.7
Weight	0.8	4.1	5.1	1.8	2.2
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	1.1	1.1	0.9
Arm fat mass (right)	0.8	3.3	3.6	1.7	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	1.5	1.2	0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.7	3.1	0.5	1.8
Ever had bowel cancer screening	0.8	0.9	1.4	0.6	1.2
Ever depressed for a whole week	0.8	0.9	1.5	-0.6	-1.2
Lung FVC	0.7	3.5	4.8	-2.2	-1.5
Chronotype (morning person)	0.7	1.7	2.7	-1.7	-0.8
Supplements: Zinc	0.7	0.8	1.3	1.1	0.5
Impedance of leg (right)	0.7	3.2	5.3	2.3	1.0
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	2.2	1.5	0.9
Allergy	0.7	1.7	2.2	-1.5	-1.1
Alcohol intake versus 10 years previously	0.7	1.1	1.7	-1.3	-0.6
Wears glasses or contact lenses	0.7	0.8	0.9	-0.9	-0.9
Primary Biliary Cirrhosis	0.6	0.9	1.0	-1.0	-0.9
BMI	0.6	3.2	3.6	1.7	1.9
Medication for hormone replacement therapy	0.6	0.6	1.3	-1.1	0.0
Illnesses of siblings	0.6	0.9	1.2	1.1	0.7
Father’s age at death	0.6	0.8	1.1	0.7	1.0
Hair/balding pattern: Pattern 3	0.6	0.9	1.5	1.2	0.5
Medication: Lansoprazole	0.6	0.7	0.9	-0.9	-0.8
High blood pressure (siblings)	0.6	0.9	1.2	-1.1	-0.8
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.0	-0.6	-1.0
Medication: Ibuprofen	0.6	0.8	0.9	0.9	0.8
Illnesses of father: Heart disease	0.6	0.9	1.6	-1.3	-0.4
Qualifications: nursing, teaching	0.6	1.0	2.0	0.0	-1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.4	1.8	-1.3	-1.0
Medication: Lisinopril	0.6	0.8	0.8	0.9	0.9
Number of operations (self-reported)	0.6	1.0	1.9	-0.2	1.4
Cholesterol lowering medication	0.6	0.9	1.2	-1.1	-0.8
Bipolar Disorder (2018)	0.5	0.8	0.9	-0.8	-1.0
Allergy or Eczema	0.5	1.4	2.0	1.4	0.9
Body mass index (BMI)	0.5	2.2	2.7	1.3	1.6
Pain all over the body in last month	0.5	0.6	0.7	0.8	0.7
Asthma	0.5	0.9	1.3	-1.2	-0.7
Tense / ‘highly strung’	0.5	0.8	1.3	-1.1	-0.5
Peak expiratory flow (PEF)	0.5	1.1	1.3	0.9	1.2
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.2	-0.2	1.1
Pulse rate, automated reading	0.5	1.6	1.6	1.3	1.3
Alcohol intake frequency.	0.5	1.1	1.2	-1.0	-1.1
Family relationship satisfaction	0.5	0.6	1.1	-0.2	-1.0
Leg pain on walking	0.5	0.6	0.8	-0.6	-0.9
Supplements: Vitamin C	0.5	0.6	1.0	-0.5	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.5	0.9	1.6	-0.4	-1.3
Commuting to job workplace: Public transport	0.5	0.6	1.3	-0.2	-1.1
Eye problems/disorders: Glaucoma	0.5	0.5	0.9	0.5	0.9
Average weekly beer plus cider intake	0.5	0.7	1.3	-1.2	-0.2
Alzheimer’s Disease (in father)	0.4	0.4	0.9	-0.9	-0.1
Prostate Cancer	0.4	0.5	0.8	0.5	-0.9
Schizophrenia (2014)	0.4	0.8	1.2	-0.7	-1.1
Hand grip strength (right)	0.4	1.0	1.8	-0.5	-1.4
Multivitamins +/- minerals	0.4	0.5	0.9	0.9	-0.1
Sitting height	0.4	2.8	3.1	1.6	1.8
Number of incorrect matches in round	0.4	0.6	1.3	-1.1	-0.1
Had other major operations	0.4	0.5	0.9	0.4	0.9
Qualifications: None of the above	0.4	0.8	1.5	0.3	1.2
Worrier / anxious feelings	0.4	0.7	0.8	0.8	0.9
Noisy workplace	0.4	0.4	0.9	-0.9	-0.1
Hair/balding pattern: Pattern 4	0.4	1.1	1.2	-1.1	-1.0
Birth weight of first child	0.4	0.7	1.0	-0.7	-1.0
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.0	0.4	-1.0
Glaucoma (self-reported)	0.4	0.5	0.8	0.4	0.9
Medication: Allopurinol	0.4	0.5	1.0	-1.0	-0.3
Had major operations	0.4	0.5	1.0	-1.0	0.1
Smoking status: Current	0.4	0.7	1.0	0.6	1.0
Financial situation satisfaction	0.4	0.5	1.0	1.0	0.2
Age started oral contraceptive pill	0.4	0.5	1.0	0.2	1.0
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	0.9	-0.9	-0.2
Alcohol drinker status: Previous	0.4	0.5	0.8	0.9	-0.3
Rheumatoid Arthritis	0.3	0.4	0.8	-0.0	-0.9
Height	0.3	6.5	7.2	2.4	2.7
Waist Hip Ratio (WHR)	0.3	1.4	1.6	1.2	1.1
Respiratory disease	0.3	0.6	0.6	-0.8	-0.8
Diabetes (father)	0.3	0.4	0.6	0.8	0.3
Townsend deprivation index at recruitment	0.3	0.4	0.6	0.5	0.8
Stomach or abdominal pain in last month	0.3	0.4	0.7	-0.8	-0.2
Chronic bronchitis/emphysema (father)	0.3	0.4	0.8	-0.9	-0.1
Nervous feelings	0.3	0.6	1.3	-1.1	0.0
Hearing difficulty/problems with background noise	0.3	0.5	1.0	0.1	-1.0
Medication: Simvastatin	0.3	0.4	0.5	-0.6	-0.7
Medication: Cholesterol lowering	0.3	0.5	0.5	-0.6	-0.7
Illnesses of mother	0.3	0.4	0.7	-0.9	0.0
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.5	0.6	0.7
Blood clot in the leg (DVT)	0.3	0.4	0.6	0.8	0.4
Medication: Paracetamol	0.3	0.5	0.7	-0.5	-0.9
Pulse wave peak to peak time	0.3	0.3	0.6	0.2	0.8
Emphysema/chronic bronchitis	0.3	0.3	0.4	0.5	0.6
Average weekly red wine intake	0.3	0.4	0.7	0.8	0.3
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.7	0.0	0.9
Back pain experienced in last month	0.3	0.4	0.7	0.8	0.1
Mineral and other dietary supplements	0.3	0.5	0.7	0.4	0.9
Medication: Gliclazide	0.3	0.4	0.7	0.2	0.8
Illnesses of father: None of the above (group 1)	0.3	0.3	0.4	0.6	0.6
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.6	-0.0	-0.8
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.5	-0.5	-0.7
Diastolic blood pressure, automated reading	0.3	0.9	1.6	-1.3	-0.5
Unable to work because of sickness or disability	0.3	0.4	0.7	-0.1	0.8
Supplements: Calcium	0.3	0.3	0.4	-0.6	-0.5
Pack years of smoking	0.3	0.5	0.5	0.6	0.7
Schizophrenia vs Biploar Disorder	0.2	0.3	0.5	0.2	0.7
Alzheimer’s Disease (including proxy)	0.2	0.2	0.3	-0.6	-0.4
Ulcerative Colitis (UC)	0.2	0.3	0.6	0.7	-0.1
Reaction Time	0.2	0.4	0.4	-0.5	-0.7
Ovarian Cancer	0.2	0.3	0.5	-0.7	-0.0
Blood Platelet Count	0.2	2.5	3.4	-1.9	-1.2
Lung FEV1/FVC ratio	0.2	0.8	1.7	-0.0	1.3
Neuroticism	0.2	0.4	0.6	-0.3	-0.8
Average weekly spirits intake	0.2	0.2	0.3	0.5	0.4
Severe depression (siblings)	0.2	0.2	0.4	-0.0	-0.6
Current tobacco smoking	0.2	0.3	0.4	0.4	0.6
Age when periods started (menarche)	0.2	0.5	0.7	-0.8	0.5
Medication: Atenolol	0.2	0.2	0.2	-0.5	0.5
Had menopause	0.2	0.2	0.4	-0.6	-0.1
Heart attack	0.2	0.2	0.3	-0.5	-0.3
Pulse wave Arterial Stiffness index	0.2	0.2	0.4	-0.1	-0.6
Standing height	0.2	2.0	2.7	1.1	1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.2	0.5	0.5
Loud music exposure frequency	0.2	0.2	0.2	0.3	-0.5
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.4	0.6	-0.0
Suffer from ‘nerves’	0.2	0.3	0.4	-0.5	-0.6
Age at last live birth	0.2	0.3	0.6	-0.8	-0.1
Illnesses of siblings: Diabetes	0.2	0.3	0.4	-0.4	-0.6
Mood swings	0.2	0.4	0.5	-0.7	-0.5
Friendships satisfaction	0.2	0.2	0.3	-0.4	-0.5
Asthma (self-reported)	0.2	0.4	0.6	-0.8	-0.5
Medication: Blood pressure	0.2	0.4	0.8	-0.9	0.0
High cholesterol (Self-reported)	0.2	0.3	0.4	-0.5	-0.7
Basal metabolic rate	0.2	0.9	1.2	0.8	1.1
Arm fat-free mass (left)	0.2	0.8	0.9	0.9	0.9
Heart attack/myocardial infarction (self-reported)	0.2	0.3	0.3	-0.6	-0.4
Impedance of whole body	0.2	1.0	1.3	1.2	0.8
Worry (Nagel 2018)	0.1	0.2	0.3	-0.3	-0.5
Irritable Bowel Disease (IBD)	0.1	0.3	0.3	0.5	-0.5
Ulcerative Colitis	0.1	0.1	0.2	0.5	-0.0
Blood Eosinophil Count	0.1	1.1	1.4	1.0	1.2
Systolic Blood Pressure	0.1	0.3	0.6	-0.8	0.1
Smoking Status	0.1	0.2	0.3	0.5	0.1
Systolic blood pressure, automated reading	0.1	0.3	0.7	-0.8	-0.1
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.2	-0.4	-0.0
Vitamin and mineral supplements	0.1	0.2	0.2	-0.5	0.4
Medication: Co-codamol	0.1	0.2	0.2	-0.3	0.5
Diabetes (mother)	0.1	0.2	0.3	0.6	0.0
Pack years adult smoking proportion	0.1	0.1	0.2	0.4	0.4
Leg fat-free mass (left)	0.1	0.4	0.8	0.0	0.9
Maternal smoking around birth	0.1	0.2	0.4	0.1	0.6
Fed-up feelings	0.1	0.2	0.3	0.5	0.3
Qualifications: CSEs or equivalent	0.1	0.1	0.2	-0.2	-0.5
Leg predicted mass (left)	0.1	0.3	0.5	-0.0	0.7
Alcohol usually taken with meals	0.1	0.2	0.2	0.4	-0.5
Hair/balding pattern: Pattern 2	0.1	0.1	0.1	0.4	-0.0
Mouth/teeth dental problems	0.1	0.2	0.3	-0.3	0.5
Diabetes (self-reported)	0.1	0.1	0.2	-0.1	0.4
Pulse rate	0.1	0.2	0.4	-0.6	0.0
Happiness	0.1	0.2	0.3	0.6	-0.1
Mouth/teeth dental problems: Dentures	0.1	0.2	0.3	0.0	-0.6
Depression (self-reported)	0.1	0.1	0.2	0.4	0.3
Exposure to tobacco smoke at home	0.1	0.2	0.2	0.3	0.5
Pulse wave reflection index	0.1	0.1	0.1	-0.3	-0.2
Arm fat-free mass (right)	0.1	0.6	0.8	0.9	0.7
Number of full brothers	0.1	0.2	0.3	-0.2	0.6
Age at first live birth	0.1	0.2	0.3	0.0	0.6
Qualifications: College or University degree	0.1	0.3	0.5	0.7	0.3
Medication for pain relief, constipation, heartburn	0.1	0.2	0.3	0.2	0.5
Migraine (self-reported)	0.1	0.1	0.1	-0.2	-0.4
Medication: Omeprazole	0.1	0.2	0.2	-0.5	0.3
Medication: Seretide 50 evohaler	0.1	0.1	0.1	0.3	0.3
Mean time to correctly identify matches	0.1	0.1	0.2	-0.0	-0.5
Arm predicted mass (right)	0.1	0.6	0.7	0.8	0.6
Commuting to job workplace: Car/motor vehicle	0.1	0.2	0.2	0.3	0.4
Diabetes diagnosed by doctor	0.1	0.2	0.4	-0.1	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.2	-0.4	0.2
Average weekly champagne plus white wine intake	0.1	0.2	0.3	0.5	0.3
Miserableness	0.1	0.2	0.4	-0.3	-0.6
Mother’s age at death	0.1	0.1	0.1	0.3	0.2
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.2	0.4	0.3
Fractured/broken bones in last 5 years	0.1	0.1	0.1	0.2	0.4
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.2	0.4	0.2
Arm predicted mass (left)	0.1	0.8	0.8	0.9	0.8
Depressed Affect (Nagel 2018)	0.0	0.1	0.1	0.3	0.2
Neuroticism (Nagel 2018)	0.0	0.0	0.1	-0.2	-0.2
Alzheimer’s Disease (in mother)	0.0	0.0	0.1	0.3	0.1
Crohns Disease (2017)	0.0	0.1	0.1	0.1	-0.4
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0
Age at First Birth	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.0	0.0	0.0	0.0
Crohns Disease (2012)	0.0	0.1	0.1	0.1	-0.3
Fasting Glucose	0.0	0.0	0.0	0.2	-0.2
HbA1C	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.0	0.0	0.0	0.0
Lupus	0.0	0.0	0.0	-0.0	-0.2
Triglycerides	0.0	0.0	0.0	0.0	0.0
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.0	0.0
Blood White Count	0.0	0.1	0.2	-0.2	-0.4
Hand grip strength (left)	0.0	0.1	0.2	0.1	-0.5
Sensitivity / hurt feelings	0.0	0.0	0.0	-0.1	-0.1
Medication: Metformin	0.0	0.0	0.0	0.1	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.0	0.0	0.0	0.2	-0.1
Tinnitus: Yes, but not now, but have in the past	0.0	0.0	0.0	-0.2	-0.2
Serious illness, injury or assault to yourself	0.0	0.0	0.0	0.2	0.1
Supplements: Glucosamine	0.0	0.1	0.1	0.3	0.2
Past tobacco smoking	0.0	0.0	0.0	0.2	0.1
Forced vital capacity (FVC)	0.0	0.2	0.3	-0.6	0.1
Neuroticism score	0.0	0.0	0.0	-0.1	-0.1
Impedance of arm (right)	0.0	0.1	0.2	-0.2	0.4
Trunk fat-free mass	0.0	0.2	0.3	0.4	0.5
Falls in the last year	0.0	0.1	0.1	-0.3	-0.1
Forced expiratory volume in 1-second (FEV1)	0.0	0.1	0.1	-0.3	0.1
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.0	0.1	-0.0
Prospective memory result	0.0	0.0	0.1	-0.3	0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.1	0.3	-0.5	-0.1
Impedance of arm (left)	0.0	0.1	0.2	0.1	0.5
Trunk predicted mass	0.0	0.2	0.2	0.4	0.5
Breastfed as a baby	0.0	0.0	0.1	-0.3	0.0
Forced vital capacity (FVC), Best measure	0.0	0.1	0.2	-0.4	-0.0
Comparative body size at age 10	0.0	0.1	0.2	0.4	-0.1
Heart disease (mother)	0.0	0.0	0.1	-0.2	-0.1
Comparative height size at age 10	0.0	0.2	0.3	0.2	-0.6
Overall health rating	0.0	0.1	0.1	-0.4	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.0	0.0	0.0	-0.2	-0.0
Smoking status: Previous	0.0	0.1	0.1	0.1	-0.4
Whole body fat-free mass	0.0	0.3	0.5	0.3	0.7
Leg fat-free mass (right)	0.0	0.3	0.3	-0.4	0.6
Commuting to job workplace: Walk	0.0	0.0	0.0	-0.2	-0.1
Whole body water mass	0.0	0.2	0.4	0.2	0.6
Leg predicted mass (right)	0.0	0.3	0.4	-0.3	0.7
Guilty feelings	0.0	0.0	0.0	-0.1	0.1
Medication: Paracetamol	0.0	0.0	0.0	0.2	-0.2
Ever smoked	0.0	0.1	0.1	-0.0	0.4
Irritability	0.0	0.0	0.1	0.3	-0.0
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.0	0.1	-0.2
Heart disease (siblings)	0.0	0.0	0.0	0.2	0.2

Hub : Genes

SLC25A10

Models

Trait associations