Hub : Genes

SLC25A24

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.3570 0.0470 0.0e+00 0.361 0.331 0.395 0.389 0.394 6.6e-46 1.8e-41 3.2e-51 2.7e-50 4.0e-51
2 GTEx Artery Aorta 0.2510 0.0770 6.9e-04 -0.004 NA 0.010 NA 0.019 5.9e-01 NA 8.4e-02 NA 3.2e-02
3 GTEx Brain Cerebellar Hemisphere 0.6140 0.0750 1.1e-11 0.535 NA 0.400 NA 0.510 3.4e-16 NA 2.3e-11 NA 3.4e-15
4 GTEx Brain Cerebellum 0.3440 0.0840 1.7e-05 0.389 NA 0.296 NA 0.376 1.6e-12 NA 2.0e-09 NA 4.5e-12
5 GTEx Brain Nucleus accumbens basal ganglia 0.2540 0.0980 5.8e-03 0.213 NA 0.256 NA 0.243 2.2e-06 NA 1.6e-07 NA 3.6e-07
6 GTEx Brain Putamen basal ganglia 0.3840 0.1280 8.4e-04 0.272 NA 0.226 NA 0.244 3.6e-07 NA 4.4e-06 NA 1.7e-06
7 GTEx Cells Transformed fibroblasts 0.1350 0.0430 8.0e-05 0.094 NA 0.042 NA 0.072 1.5e-07 NA 4.0e-04 NA 4.2e-06
8 GTEx Esophagus Mucosa 0.3940 0.0540 0.0e+00 0.373 NA 0.409 NA 0.409 4.1e-26 NA 3.0e-29 NA 3.4e-29
9 GTEx Esophagus Muscularis 0.1810 0.0580 9.7e-05 0.152 NA 0.070 NA 0.116 1.7e-09 NA 4.6e-05 NA 1.5e-07
10 GTEx Lung 0.1620 0.0469 8.0e-06 0.065 NA 0.087 NA 0.074 9.7e-06 NA 3.6e-07 NA 2.4e-06
11 GTEx Muscle Skeletal 0.0837 0.0356 6.8e-03 0.030 NA 0.013 NA 0.022 5.3e-04 NA 1.7e-02 NA 2.7e-03
12 GTEx Pancreas 0.1460 0.0530 1.3e-03 0.119 NA 0.155 NA 0.147 1.1e-05 NA 4.5e-07 NA 9.2e-07
13 GTEx Skin Not Sun Exposed Suprapubic 0.2310 0.0580 4.4e-07 0.222 NA 0.197 NA 0.207 2.1e-12 NA 5.2e-11 NA 1.4e-11
14 GTEx Skin Sun Exposed Lower leg 0.2400 0.0460 6.9e-13 0.194 NA 0.193 NA 0.207 5.7e-16 NA 7.0e-16 NA 5.4e-17
15 GTEx Testis 0.2920 0.0640 1.5e-07 0.221 NA 0.334 NA 0.342 3.5e-10 NA 1.8e-15 NA 6.6e-16
16 NTR Blood 0.0288 0.0114 4.7e-04 0.024 0.007 0.016 0.001 0.007 1.9e-08 2.5e-03 4.1e-06 1.1e-01 2.5e-03
17 ROSMAP Brain Pre-frontal Cortex 0.2621 0.0475 0.0e+00 0.224 0.176 0.215 0.225 0.224 2.6e-28 4.9e-22 3.4e-27 1.7e-28 2.3e-28
18 TCGA Breast Invasive Carcinoma 0.0426 0.0230 5.6e-05 0.001 0.015 0.019 NA 0.010 1.7e-01 3.0e-04 7.0e-05 NA 2.7e-03
19 TCGA Head and Neck Squamous Cell Carcinoma 0.0912 0.0400 2.7e-07 0.041 0.055 0.051 NA 0.022 1.9e-05 8.8e-07 1.8e-06 NA 1.3e-03
20 TCGA Kidney Renal Clear Cell Carcinoma 0.0775 0.0338 2.8e-04 0.017 0.026 0.014 NA 0.015 4.1e-03 5.5e-04 8.8e-03 NA 7.7e-03
21 TCGA Brain Lower Grade Glioma 0.1116 0.0466 6.7e-04 0.008 0.030 0.017 NA 0.018 3.7e-02 2.1e-04 4.0e-03 NA 3.6e-03
22 TCGA Lung Squamous Cell Carcinoma 0.0360 0.0175 1.2e-03 0.017 0.019 0.017 NA 0.013 4.1e-03 2.9e-03 4.3e-03 NA 1.0e-02
23 TCGA Prostate Adenocarcinoma 0.1567 0.0498 4.3e-12 0.121 0.116 0.112 NA 0.114 1.2e-12 3.6e-12 8.9e-12 NA 6.4e-12
24 TCGA Testicular Germ Cell Tumors 0.2110 0.0990 5.0e-04 0.065 0.074 0.019 NA 0.056 2.6e-03 1.3e-03 6.7e-02 NA 4.8e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bipolar Disorder (2018) 0.6 0.9 2.6 0.7 -1.0 0.9 0.9 1.0 0.7 -1.4 -1.2 0.7 1.0 0.8 0.8 -1.0 -1.2 1.2 -1.0 0.7 -1.0 -1.6 0.6 0.4 -1.4 0.3 -0.8
Bipolar Disorder or Schizophrenia 1.8 4.3 10.3 2.9 -0.9 2.9 2.8 2.0 2.4 0.8 -2.8 2.6 -0.7 0.9 3.2 -2.8 -2.5 -0.7 -0.8 2.6 0.3 -0.7 2.5 1.9 -0.2 2.9 0.8
Depressed Affect (Nagel 2018) 0.8 1.7 11.4 -1.2 0.5 -1.6 -1.5 -3.4 -1.6 -0.3 1.4 -1.5 0.4 -1.0 -1.6 1.6 1.4 -0.1 0.9 -1.5 0.4 -0.2 -1.1 -0.6 -0.4 -1.0 -1.1
Depression (Nagel 2018) 0.2 0.3 0.9 0.6 -0.8 0.4 0.5 -0.3 0.6 0.6 -0.8 0.4 -0.2 0.6 0.3 -0.8 -0.5 -0.3 -0.5 0.3 0.6 -0.0 -0.1 1.0 0.0 0.9 -0.4
Intelligence (Savage-Jansen 2018) 0.2 0.6 3.2 -0.3 0.4 0.0 0.1 -0.6 0.5 -0.5 -0.3 -0.2 1.8 1.1 -0.2 -0.0 -0.3 0.9 -1.2 0.1 -1.1 -1.5 -0.1 0.1 -1.4 -0.7 -1.1
Neuroticism (Nagel 2018) 0.2 0.5 2.1 0.1 0.2 -0.5 -0.5 -1.2 -0.2 1.0 0.8 -0.5 -0.5 -1.2 -0.4 0.7 0.7 -1.2 1.2 -0.4 1.4 0.4 0.3 0.5 0.5 0.3 0.1
Schizophrenia (2018) 2.5 5.2 12.1 3.2 -0.3 3.0 2.8 1.9 2.5 2.2 -2.6 2.7 -1.7 0.5 3.5 -2.7 -2.2 -1.9 -0.2 2.8 1.2 0.4 2.8 2.1 0.8 3.5 1.7
Schizophrenia vs Biploar Disorder 1.4 1.8 4.6 1.2 0.0 1.3 1.0 0.5 0.9 2.0 -0.6 1.2 -1.6 -1.2 1.4 -1.0 -0.3 -2.1 1.4 1.2 2.1 1.3 1.4 0.6 1.4 1.9 1.7
Worry (Nagel 2018) 0.5 1.1 3.1 -0.3 -0.7 -1.0 -1.1 -0.4 -0.6 1.1 1.2 -1.2 -1.4 -1.8 -0.7 1.2 1.4 -1.3 1.7 -1.1 1.2 0.8 0.1 -0.2 1.1 -0.5 0.4
Alzheimer’s Disease (in mother) 2.0 2.4 5.3 2.1 -0.2 1.7 1.6 2.3 1.9 1.9 -1.2 1.7 -1.9 -0.7 1.4 -1.9 -1.1 -1.6 0.8 1.6 1.1 1.3 1.0 0.9 1.5 1.9 1.7
Alzheimer’s Disease (in father) 2.4 2.6 6.0 -0.9 1.6 -1.2 -1.4 -2.0 -2.0 2.4 2.0 -1.3 -0.4 -1.9 -1.1 1.5 1.9 -2.3 2.1 -1.0 1.5 2.4 0.3 -0.0 2.2 -0.4 1.4
Alzheimer’s Disease (including proxy) 0.5 0.7 3.7 0.6 0.3 0.3 0.2 0.6 0.1 1.9 0.3 0.3 -1.1 -0.7 -0.0 -0.4 0.0 -1.4 0.8 0.3 0.6 1.5 -0.1 0.1 1.6 0.8 1.0
Crohns Disease (2017) 1.1 2.4 6.1 -1.9 -0.4 -1.5 -1.2 -1.9 -1.0 -2.1 0.5 -1.2 1.4 0.6 -2.0 1.2 0.6 2.1 -0.9 -1.4 -2.4 -1.7 -1.7 -0.9 -1.7 -2.5 -1.8
Irritable Bowel Disease (IBD) 0.5 1.2 3.6 -1.0 -0.0 -1.1 -0.6 -1.4 -0.6 -1.4 0.3 -0.4 1.1 0.7 -1.6 0.6 0.3 1.7 -1.0 -0.8 -1.5 -1.4 -1.0 0.3 -1.2 -1.9 -1.2
Ulcerative Colitis (UC) 0.2 0.3 1.2 -0.3 0.8 -0.8 -0.4 -0.7 -0.6 -0.3 0.6 -0.0 0.3 0.3 -1.1 0.4 0.3 0.5 -0.3 -0.5 -0.1 -0.3 -0.3 1.0 -0.2 -1.1 -0.4
Major Depression (MDD) 1.0 1.2 3.2 -1.1 -0.9 -1.6 -1.5 -1.3 -1.8 0.2 0.9 -1.3 0.7 -1.2 -1.4 1.4 1.6 -0.2 1.0 -1.6 -0.2 -0.0 -0.1 0.5 0.4 -1.4 -0.1
Reaction Time 1.5 2.9 7.1 2.2 -0.5 2.5 2.4 1.3 2.3 1.3 -2.2 2.5 -1.1 -0.1 2.5 -2.5 -2.0 -1.2 0.1 2.2 0.3 -0.4 1.2 0.6 0.1 2.7 0.8
Verbal and Numeric Reasoning (VNR) 0.1 0.2 0.8 -0.1 0.9 0.3 0.2 0.0 0.9 -0.3 -0.2 0.0 0.8 0.5 0.5 -0.1 -0.2 0.8 -0.7 0.2 -0.5 -0.6 0.3 -0.5 -0.5 -0.1 0.0
Breast Cancer 0.2 0.6 1.9 -1.1 0.4 -0.9 -1.0 -0.7 -1.1 0.2 1.4 -1.0 -1.0 -0.2 -0.6 1.0 0.7 -0.8 0.5 -0.9 0.1 0.4 0.5 -0.1 0.2 -1.2 -0.3
Ovarian Cancer 0.1 0.1 0.7 -0.1 0.3 -0.3 -0.2 -0.2 -0.2 -0.5 0.1 -0.1 0.8 0.2 -0.6 0.1 0.3 0.6 -0.3 -0.1 -0.2 0.5 -0.0 0.2 0.5 -0.5 0.2
Prostate Cancer 0.6 0.9 1.9 1.1 -0.2 1.1 1.2 0.6 1.2 -0.2 -1.2 1.2 -0.1 1.1 1.1 -1.2 -1.3 0.5 -1.1 1.1 -0.5 -0.6 0.4 1.1 -0.6 1.4 0.3
Age at First Birth 0.5 0.7 2.0 0.7 -0.7 0.7 0.4 1.0 1.1 0.7 -0.3 0.8 -1.1 -0.4 1.3 -0.4 -0.2 -0.8 0.5 0.6 1.4 0.5 0.9 -0.2 0.3 1.2 1.1
Bipolar Disorder (2011) 3.0 2.9 7.2 0.1 -0.5 0.9 1.0 0.8 1.2 -2.6 -2.0 0.8 2.6 2.1 0.4 -1.0 -1.7 2.6 -2.3 0.6 -2.7 -2.6 -1.2 -0.8 -2.4 0.0 -1.9
Body Mass Index (BMI) (2010) 0.5 0.7 2.1 -1.2 -0.8 -1.2 -1.0 -0.4 -1.3 -0.3 0.6 -0.9 0.8 0.4 -1.5 0.8 0.7 0.3 -0.4 -1.2 0.1 0.2 -1.0 0.4 -0.1 -1.0 -1.0
Coronary Artery Disease (CAD) 0.6 0.7 3.5 0.6 1.5 0.3 0.4 -0.3 0.4 -0.4 -0.3 0.3 1.9 1.6 -0.1 -0.3 -0.7 1.0 -1.6 0.5 -0.6 -0.6 -0.5 0.4 -0.6 0.0 -0.8
Crohns Disease (2012) 1.9 3.1 6.2 -2.2 1.3 -1.7 -1.5 -2.2 -1.0 -2.0 0.7 -1.4 2.1 1.1 -2.0 1.6 0.7 2.4 -1.4 -1.5 -2.5 -1.2 -2.4 -1.8 -1.5 -2.3 -1.7
Mean Putamen Volume 0.7 0.7 3.2 0.4 -1.8 0.9 1.0 0.9 0.9 -0.7 -1.4 0.9 0.1 0.3 1.1 -1.0 -1.0 0.3 -0.3 0.8 -0.6 -1.0 0.5 0.5 -0.9 0.9 -0.4
Fasting Glucose 1.1 1.3 5.2 0.2 -0.3 0.0 -0.2 0.2 -0.2 1.7 0.6 -0.1 -2.3 -2.2 -0.1 0.0 0.8 -2.0 2.2 -0.5 1.7 1.3 0.9 0.0 1.4 0.5 0.8
HbA1C 2.3 2.5 6.0 2.2 -1.6 2.2 2.3 1.3 2.2 0.9 -2.3 2.3 -0.2 0.8 1.8 -2.4 -1.5 -0.3 -0.8 1.9 -0.1 -0.0 1.1 1.2 0.5 2.1 1.1
HDL Cholesterol 0.6 1.0 2.7 0.8 -0.1 1.2 1.2 0.7 1.2 -1.5 -1.6 1.0 0.5 0.4 0.8 -1.4 -1.1 1.4 -0.6 1.0 -1.1 -1.5 0.7 -0.1 -0.9 0.1 0.2
LDL Cholesterol 0.5 0.8 3.8 1.0 -1.3 0.8 0.9 1.0 0.1 0.5 -1.0 1.1 0.1 0.4 0.5 -1.2 -0.8 -0.8 -0.1 0.8 1.5 0.2 1.2 1.9 0.1 1.3 0.1
Lupus 1.8 2.7 5.8 2.0 -0.0 2.4 2.2 1.2 2.2 0.8 -1.6 2.0 -1.4 1.3 2.3 -2.1 -2.1 -0.9 -0.9 2.4 0.3 -0.5 1.8 1.4 -0.4 2.4 0.4
Neuroticism (2016) 0.7 1.0 3.0 1.4 -0.4 1.5 1.5 0.3 1.4 -0.1 -1.2 1.5 0.5 -0.0 1.7 -1.4 -1.1 0.1 -0.1 1.3 0.4 -0.5 0.8 0.5 -0.2 1.5 0.4
Primary Biliary Cirrhosis 2.7 3.9 8.3 2.2 -0.5 2.6 2.8 1.9 2.3 -0.1 -2.8 2.8 0.6 2.2 1.9 -2.8 -2.9 0.6 -2.1 2.4 -0.8 -1.7 1.0 1.9 -1.1 2.1 -0.2
Rheumatoid Arthritis 0.2 0.2 0.7 -0.6 0.8 -0.2 -0.2 -0.6 -0.0 0.9 0.3 -0.3 0.2 0.8 -0.1 0.3 0.1 0.1 -0.8 -0.3 0.1 0.8 -0.8 -0.2 0.3 0.3 -0.2
Schizophrenia (2014) 1.6 3.4 7.4 2.5 -0.5 2.5 2.3 1.3 2.0 1.6 -2.2 2.3 -1.8 -0.0 2.7 -2.4 -1.8 -1.6 0.2 2.2 1.1 0.1 2.4 1.5 0.5 2.6 1.4
Triglycerides 1.2 1.9 5.9 -0.9 -1.0 -1.4 -1.3 -0.6 -2.4 0.8 1.8 -1.1 -0.7 -1.7 -1.6 1.3 1.6 -1.6 1.9 -1.5 2.0 1.8 -0.1 0.6 1.4 -0.8 -0.2
Type 2 Diabetes (T2D) (2012) 2.2 2.5 8.3 -1.2 0.1 -1.0 -0.8 -1.1 -1.1 -2.4 -0.1 -0.6 1.7 1.3 -1.5 0.7 -0.3 2.2 -1.4 -1.0 -2.1 -2.1 -2.6 -1.3 -2.6 -1.3 -2.9
Ulcerative Colitis 0.4 0.6 2.3 -0.4 1.5 -1.1 -0.8 -0.7 -1.1 0.0 1.3 -0.7 0.2 -0.1 -1.4 0.9 0.9 0.1 0.1 -0.8 0.1 0.8 -0.4 0.6 0.5 -1.0 0.1
Blood Eosinophil Count 0.1 0.8 2.3 -0.6 -0.5 -1.5 -1.0 -1.1 -1.4 -0.8 0.5 -1.1 0.7 -0.1 -1.5 1.0 0.8 0.4 0.1 -1.2 0.8 0.1 -0.7 1.2 -0.1 -1.0 -0.3
Blood Platelet Count 0.1 0.7 3.7 0.2 -1.9 -0.5 -0.7 0.0 -0.8 0.4 0.2 -0.9 -0.8 -1.5 -0.2 0.5 0.8 -1.1 1.4 -0.8 1.1 0.4 0.6 0.4 0.1 0.8 -0.2
Blood Red Count 0.0 0.2 1.3 -0.2 -0.9 -0.5 -0.2 1.0 -0.0 0.3 -0.0 -0.2 -1.2 -0.6 -0.3 0.1 0.3 -0.3 0.5 -0.3 0.3 0.1 0.2 1.0 0.3 -0.2 0.2
Blood White Count 2.1 15.9 43.4 0.5 -0.3 -2.1 -2.1 -1.1 -3.5 5.0 3.4 -2.1 -4.1 -6.4 -1.5 2.0 3.9 -6.2 6.6 -1.5 6.4 6.0 3.0 2.7 6.1 0.0 4.8
Heel T-Score 0.4 3.1 8.1 2.2 1.3 2.7 2.4 1.0 2.7 0.5 -1.5 2.5 -0.1 1.3 2.8 -2.2 -2.2 -0.0 -1.1 2.7 -0.3 0.6 0.0 -0.8 0.3 2.9 0.6
BMI 0.2 1.2 5.8 -0.8 -1.4 -1.3 -0.8 -1.9 -1.0 -0.3 -0.2 -0.8 2.4 1.4 -1.6 0.4 0.3 0.8 -1.3 -0.8 0.1 -0.4 -1.4 1.4 -0.5 -0.7 -0.9
Height 0.2 2.9 9.9 0.1 -0.6 -0.9 -0.8 -0.6 -1.1 1.6 1.4 -0.7 -2.7 -3.1 -0.9 0.8 1.7 -2.1 3.0 -1.2 2.2 1.8 1.8 0.6 2.5 -1.0 2.5
Waist Hip Ratio (WHR) 0.3 1.4 4.5 0.4 -1.5 0.5 0.7 1.4 1.0 -1.6 -1.6 0.7 1.6 1.4 0.1 -0.9 -1.0 1.5 -1.5 0.2 -1.7 -2.1 0.1 0.5 -1.5 -0.6 -1.0
Systolic Blood Pressure 0.1 0.5 3.5 0.7 -0.6 0.8 0.6 1.9 0.9 -0.6 -0.3 1.0 0.1 -0.5 0.9 -0.7 -0.6 0.1 0.4 0.5 -0.4 -0.7 0.2 -0.6 -0.4 0.7 -0.3
Smoking Status 0.3 0.6 3.4 0.8 1.8 0.3 0.6 -0.1 0.5 -0.6 -0.3 0.4 1.3 1.0 0.1 -0.6 -0.9 0.8 -1.1 0.6 -0.3 -0.8 -0.8 0.9 -0.7 0.4 -0.9
Allergy or Eczema 0.3 0.7 5.4 -0.8 2.3 -0.6 -0.6 -1.7 -0.7 1.2 0.2 -0.7 0.3 0.7 -0.3 0.4 0.5 -0.3 -0.5 -0.5 0.8 0.9 -0.2 0.6 0.4 0.3 0.2
Cardiovascular Disease 0.2 0.5 2.5 -0.0 -0.2 -0.4 -0.5 -0.2 -0.9 -0.1 0.4 -0.5 -0.4 -1.4 -0.7 0.3 0.8 -0.5 1.3 -0.5 1.6 1.1 -0.1 -0.4 0.8 -0.1 0.8
Hypothyroidism (self reported) 0.5 1.2 8.8 -0.5 -0.3 -1.2 -1.2 -1.8 -0.5 0.8 1.0 -1.3 3.0 0.0 -1.2 1.2 1.1 -0.1 0.2 -0.8 -0.3 0.9 -1.8 -0.6 0.7 -0.2 -0.7
Respiratory disease 0.3 0.6 2.2 -0.5 0.1 -1.0 -0.8 -1.2 -1.0 0.8 1.0 -0.9 -0.2 -0.5 -1.5 0.9 0.9 -0.7 0.5 -0.5 0.3 0.8 -0.3 0.1 0.8 -1.2 0.6
Type 2 Diabetes (T2D) (2018) 0.4 0.8 2.7 -0.6 1.2 -0.2 -0.2 -0.9 -0.2 -1.6 -0.1 -0.2 1.5 1.4 -0.2 0.2 -0.5 1.3 -1.3 -0.2 -0.5 -0.5 -1.6 -0.9 -1.0 -0.2 -1.0
Lung FEV1/FVC ratio 0.1 0.5 2.1 1.1 -0.8 0.6 0.6 0.4 0.5 0.9 -0.5 0.7 0.5 0.5 0.9 -0.6 -0.6 -0.6 -0.4 0.9 0.4 0.2 0.6 1.3 0.4 1.4 0.1
Lung FVC 0.2 1.0 2.9 1.1 0.7 1.2 1.1 0.1 1.5 0.5 -1.3 1.1 1.3 0.7 1.7 -1.1 -1.0 0.2 -0.7 1.5 -0.7 -1.1 1.0 0.7 -0.5 1.3 0.3
Neuroticism 0.1 0.2 2.6 0.4 0.6 0.1 0.1 -1.6 0.1 0.5 0.1 0.1 0.1 -0.0 0.2 0.0 -0.0 -0.2 0.0 0.1 0.4 -0.3 -0.1 0.4 -0.1 0.6 -0.0
Chronotype (morning person) 1.6 3.7 8.8 2.0 -1.7 2.6 2.3 2.3 2.6 -0.3 -3.0 2.5 0.8 1.1 2.6 -2.4 -2.0 1.0 -1.3 2.2 -2.1 -1.9 1.7 0.1 -0.9 1.9 0.8
Hair Pigment 0.1 2.0 14.8 1.3 3.9 1.5 1.1 0.6 1.7 1.5 -1.1 1.2 0.7 1.1 2.0 -0.9 -1.1 0.0 -1.2 1.6 0.4 0.9 0.5 0.0 0.8 2.2 1.5
Tanning 0.0 0.4 2.0 -0.4 -0.9 -0.5 -0.5 -0.3 -0.2 0.2 0.4 -0.3 0.3 0.8 -0.5 0.5 -0.0 0.1 -0.7 -0.5 0.5 0.8 -1.4 -1.2 0.2 0.4 -0.5
Hand grip strength (left) 0.2 0.5 1.5 -0.0 1.0 -0.7 -0.5 0.8 -0.6 -0.3 0.9 -0.4 1.2 -0.7 -0.8 0.6 0.9 0.4 0.5 -0.4 0.5 0.2 0.7 0.3 0.7 -1.1 1.0
Number of treatments/medications taken 0.7 1.3 5.4 -1.4 0.5 -1.5 -1.4 -1.4 -1.6 -0.6 0.8 -1.0 1.1 0.2 -1.9 1.1 0.9 0.6 -0.2 -1.4 -0.4 -0.0 -2.3 -0.6 -0.5 -1.1 -1.5
Average weekly spirits intake 0.5 0.6 4.5 0.2 2.1 -0.0 -0.2 -0.7 0.0 1.2 0.8 0.1 -0.6 -0.5 0.7 0.3 0.2 -0.7 0.5 0.2 0.8 1.2 -0.3 -0.2 0.7 1.1 0.6
Sensitivity / hurt feelings 0.3 0.5 4.6 0.2 2.1 0.1 0.1 -0.4 0.2 -0.2 0.1 0.1 1.2 0.6 0.4 0.0 -0.3 0.5 -0.6 0.3 -0.6 -1.0 -0.1 0.7 -1.0 0.7 -0.6
Frequency of depressed mood in last 2 weeks 0.2 0.3 2.0 -0.0 -0.7 -0.0 -0.1 -0.5 0.3 1.4 -0.4 -0.2 -1.1 0.1 0.2 -0.1 -0.0 -0.9 0.0 -0.1 0.9 0.2 -0.4 0.5 0.2 1.0 -0.4
Hearing difficulty/problems: Yes 0.4 0.5 5.5 0.6 2.3 -0.0 0.1 -0.0 0.2 1.3 0.6 -0.1 -0.2 0.8 -0.0 -0.0 -0.3 -0.8 -0.5 0.6 0.7 0.0 0.5 1.4 -0.1 0.4 0.1
Relative age of first facial hair 0.3 0.6 1.4 -0.5 -1.0 -0.9 -0.9 -0.5 -0.3 -0.5 0.8 -0.6 0.3 -1.0 -1.2 0.9 1.1 0.0 0.9 -1.1 -0.6 0.3 -0.3 -0.9 0.5 -1.2 0.6
Other serious medical condition/disability diagnosed by doctor 0.5 0.6 2.5 -0.8 -0.6 -0.9 -1.0 -1.6 -1.1 0.1 0.9 -0.9 -0.1 -0.6 -0.8 0.9 0.8 -0.3 0.6 -1.0 -0.0 0.6 -1.2 -0.7 0.1 -0.2 -0.6
Ever used hormone-replacement therapy (HRT) 0.6 0.8 3.1 1.0 -1.8 0.9 0.9 0.7 0.1 0.5 -1.1 0.8 -0.9 -0.7 1.1 -0.9 -0.6 -1.2 0.8 0.9 0.4 -0.3 1.1 1.2 0.1 0.9 0.1
Ever had hysterectomy (womb removed) 0.1 0.1 0.8 0.1 -0.7 0.1 0.1 0.6 0.3 -0.9 -0.1 0.1 0.2 0.5 0.3 -0.2 -0.1 0.6 -0.5 -0.0 -0.3 0.0 -0.3 -0.5 -0.4 0.2 -0.1
Systolic blood pressure, automated reading 0.3 0.9 3.4 1.0 -0.9 1.2 1.0 1.1 1.3 0.1 -1.1 1.2 -0.5 0.2 1.5 -1.3 -1.1 -0.4 -0.1 1.1 0.6 -0.2 0.4 0.2 -0.3 1.9 -0.3
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.3 -0.6 -0.3 -0.4 -0.4 -0.1 -0.7 -1.1 0.1 -0.3 0.7 0.6 -0.2 0.3 -0.0 1.0 -0.6 -0.3 -0.2 0.2 -1.2 -1.1 -0.6 -0.2 -0.1
Angina 0.5 0.7 2.4 -0.9 1.5 -1.0 -0.9 -1.1 -1.2 -0.7 1.0 -0.9 0.4 -0.2 -1.5 0.8 0.7 0.3 0.1 -1.0 -0.2 0.2 -0.9 -0.3 -0.3 -1.1 -0.6
Medication for hormone replacement therapy 0.4 0.4 1.5 0.5 -0.6 0.6 0.5 0.6 0.2 -0.8 -0.5 0.7 1.2 0.5 0.3 -0.6 -0.8 0.4 -0.5 0.8 -0.4 -1.0 -0.3 0.0 -1.0 0.3 -1.2
Vitamin and mineral supplements 0.6 0.9 1.9 1.3 -0.3 1.2 1.1 1.3 1.1 -0.9 -1.0 0.9 -0.2 -0.0 1.4 -1.2 -1.1 0.4 -0.1 1.0 -0.1 -1.1 0.6 0.4 -0.9 1.3 -0.5
Supplements: Zinc 0.5 0.5 3.2 -0.7 0.8 -0.3 -0.2 -0.3 -0.6 0.5 0.5 -0.2 -1.8 -0.6 -0.5 0.3 0.6 -1.0 0.8 -0.3 0.3 0.5 0.9 0.2 0.8 -1.0 0.8
Medication: Co-codamol 1.1 1.3 3.2 -1.7 0.8 -1.4 -1.4 -1.3 -1.5 -0.4 1.5 -1.8 -0.2 -0.1 -1.6 1.6 1.1 -0.0 0.2 -1.2 0.3 0.6 -1.2 -0.9 -0.1 -1.4 -0.9
Medication: Metformin 0.4 0.6 2.3 0.1 -0.9 0.3 0.5 -0.5 0.5 -1.0 -1.0 0.8 0.9 1.5 0.2 -0.6 -1.1 0.8 -1.3 0.5 -0.2 -0.6 -0.6 0.5 -0.7 0.1 -0.8
Diabetes (father) 0.5 0.6 3.4 0.4 -1.3 0.1 0.1 0.0 -0.7 0.4 -0.0 0.3 -1.2 -1.0 0.2 -0.3 0.2 -1.1 1.1 0.1 1.8 0.9 0.6 0.6 0.8 0.9 0.8
Diabetes (mother) 1.1 1.5 7.6 -1.0 -1.3 -0.7 -0.6 -0.6 -1.1 -1.8 -0.1 -0.6 0.5 0.6 -0.7 0.5 0.0 1.0 -0.5 -0.9 -1.4 -2.2 -1.0 -0.5 -2.4 -1.1 -2.8
Severe depression (siblings) 0.4 0.4 1.1 -0.9 -0.2 -1.0 -0.9 -0.9 -0.8 0.2 0.7 -0.7 -0.1 -0.6 -1.0 0.8 0.8 -0.3 0.6 -1.0 0.5 0.2 -0.2 0.1 0.1 -0.8 -0.2
Pack years adult smoking proportion 0.8 1.3 4.5 -1.2 -0.6 -0.6 -0.6 -1.7 -0.5 -2.1 -0.5 -0.4 1.6 0.4 -0.9 0.3 0.0 1.5 -0.5 -0.9 -0.8 -1.3 -1.5 -1.5 -1.5 -1.3 -1.6
Impedance of leg (right) 0.6 2.7 7.3 -1.3 2.6 -1.4 -1.5 -0.3 -1.9 0.8 2.7 -1.6 -1.8 -2.5 -1.1 2.0 1.8 -1.6 2.5 -1.2 1.2 1.5 0.3 -1.1 1.3 -1.7 0.1
Leg fat-free mass (left) 0.2 1.0 3.1 0.8 -1.2 0.6 0.9 -0.4 1.1 -0.7 -1.5 0.8 1.2 1.6 0.4 -1.1 -1.2 1.4 -1.8 0.6 0.0 -1.1 -0.5 1.1 -0.8 0.9 0.0
Trunk fat percentage 0.1 0.6 4.0 0.2 0.6 -0.2 0.2 -1.5 -0.3 1.2 -0.4 0.2 0.2 0.3 -0.4 -0.4 -0.1 -0.9 -0.0 0.0 1.8 0.2 -0.1 2.0 0.4 0.4 -0.1
Hand grip strength (right) 0.2 0.5 2.6 1.0 1.4 0.4 0.5 1.5 0.6 -0.5 -0.2 0.8 1.6 0.3 0.2 -0.4 -0.3 0.7 -0.3 0.7 0.4 -0.5 0.9 0.9 0.1 -0.1 0.7
Townsend deprivation index at recruitment 0.2 0.3 2.0 -0.2 1.4 -0.1 -0.0 0.3 -0.1 1.2 -0.3 0.1 0.4 0.1 -0.0 -0.1 -0.0 -0.7 -0.1 -0.0 0.6 -0.3 0.3 1.4 -0.2 0.6 -0.5
Current tobacco smoking 3.0 5.0 10.0 2.5 0.1 2.7 2.8 1.7 2.3 -0.8 -3.2 2.6 1.7 2.2 2.5 -2.9 -3.1 1.0 -2.2 2.7 -1.8 -2.9 0.9 2.0 -2.1 2.2 -1.3
Average weekly fortified wine intake 0.9 1.1 2.3 -1.5 1.1 -1.3 -1.2 -1.4 -1.3 0.9 1.1 -1.4 0.5 1.1 -1.4 1.2 0.7 -0.3 -0.8 -0.9 -0.3 1.1 -1.3 -0.1 0.4 -1.0 -0.6
Maternal smoking around birth 0.9 1.2 10.7 -0.3 3.3 -0.1 0.1 -0.1 0.1 -0.5 0.6 0.2 1.0 1.6 -0.4 0.0 -0.8 1.1 -1.5 0.4 -0.8 -1.1 -1.7 -0.2 -1.4 -0.4 -1.8
Fed-up feelings 0.4 0.8 3.3 0.0 0.4 -0.8 -0.8 -1.8 -0.8 1.0 1.1 -1.0 0.1 -1.5 -0.4 0.8 1.1 -1.1 1.5 -0.7 1.4 0.2 0.4 0.7 0.5 0.1 0.2
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 2.0 0.5 0.1 0.4 0.5 -0.7 0.2 0.2 -0.6 0.6 -0.1 1.0 0.4 -0.6 -0.8 -0.0 -0.9 0.3 0.7 0.0 -0.6 0.7 -0.5 1.4 -0.8
Relative age voice broke 0.2 0.4 1.4 -0.5 -0.7 -0.4 -0.4 -0.8 -0.2 0.5 0.3 -0.3 -0.5 -0.3 -0.5 0.5 0.7 -0.4 0.4 -0.4 -0.6 1.0 0.1 -0.7 1.2 -0.6 1.0
Taking other prescription medications 1.3 2.0 5.8 -1.6 -0.5 -1.4 -1.3 -1.9 -1.5 -1.6 0.4 -1.2 2.4 1.0 -1.6 1.1 0.6 1.4 -1.0 -1.4 -1.1 -1.2 -2.1 -0.3 -1.6 -1.0 -2.4
Age when periods started (menarche) 0.7 1.6 5.3 1.5 -1.2 0.9 1.1 2.1 1.0 1.4 -0.8 1.2 -1.0 -0.2 1.4 -0.9 -0.5 -0.9 0.1 1.0 1.1 0.3 2.2 2.3 1.1 1.1 1.7
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 1.8 0.3 0.3 0.7 0.7 0.3 0.4 -0.4 -0.7 0.8 0.8 1.3 0.7 -0.6 -1.0 0.5 -1.2 0.9 -0.1 -1.0 0.1 0.6 -1.1 0.6 -1.1
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.2 4.7 0.4 -0.4 0.9 0.9 0.6 1.2 -2.2 -0.9 1.0 1.5 0.5 0.6 -1.0 -1.0 2.0 -0.8 0.8 -1.7 -1.2 -1.0 -1.2 -1.1 -0.1 -0.5
Tinnitus: Yes, but not now, but have in the past 0.7 0.8 1.8 0.7 0.6 0.8 1.0 0.1 1.0 -0.9 -1.0 1.1 0.9 0.9 0.4 -1.1 -1.2 1.3 -1.1 0.6 -0.4 -1.3 -0.5 0.8 -1.1 0.3 -0.8
Qualifications: CSEs or equivalent 0.1 0.2 1.6 -0.5 -0.5 -0.2 -0.3 -1.3 -0.2 -0.8 0.2 -0.5 0.4 -0.0 0.1 0.3 0.2 0.5 -0.0 -0.4 0.1 -0.1 -0.2 -0.6 -0.4 0.2 -0.2
Serious illness, injury or assault to yourself 2.2 2.6 8.8 -0.1 -0.5 0.4 0.6 -1.4 0.7 -2.5 -1.2 0.6 2.5 1.9 -0.1 -0.6 -1.3 2.3 -2.0 0.4 -2.3 -3.0 -1.1 -0.3 -2.8 -0.6 -2.5
High blood pressure 0.1 0.2 1.8 0.3 -1.3 0.1 0.1 0.2 -0.1 0.2 -0.3 0.1 0.1 -0.6 -0.1 -0.4 0.0 -0.5 0.6 -0.0 0.8 0.8 -0.6 0.0 0.6 0.6 0.2
Hayfever, allergic rhinitis or eczema 0.2 0.3 2.7 -0.4 1.6 0.0 0.0 -1.3 -0.1 0.9 -0.3 -0.0 -0.1 0.6 0.2 -0.2 -0.1 -0.3 -0.5 0.0 0.8 0.6 0.2 0.6 0.2 0.6 0.4
Multivitamins +/- minerals 0.3 0.3 1.3 0.0 0.7 0.5 0.5 -0.1 0.6 0.6 -0.5 0.5 0.3 1.2 0.4 -0.4 -0.7 0.3 -1.1 0.7 -1.1 -0.3 -0.3 -0.3 -0.2 0.2 0.1
Stomach or abdominal pain in last month 0.4 0.5 2.1 -0.3 -1.2 -0.3 -0.3 -0.6 -0.7 0.9 -0.2 -0.2 -1.4 -0.8 -0.3 0.1 0.5 -1.0 0.7 -0.5 1.3 0.7 0.3 0.7 0.7 0.3 0.5
Supplements: Glucosamine 1.1 1.4 3.3 -1.7 1.1 -1.3 -1.4 -1.5 -1.1 -0.4 0.7 -1.4 0.3 0.7 -1.2 1.4 0.8 0.7 -0.7 -1.2 -1.4 -0.8 -1.5 -1.4 -1.3 -0.9 -1.8
Diverticular disease/diverticulitis (self-reported) 0.7 0.8 4.2 0.2 0.5 0.8 0.9 0.1 0.7 -0.3 -1.1 0.7 0.4 2.0 0.9 -0.8 -1.3 0.6 -1.8 0.9 -0.2 -0.7 -0.2 0.4 -1.2 1.0 -0.5
Medication: Atenolol 0.7 0.8 3.4 -0.9 0.7 -0.7 -0.6 -0.4 -0.4 -1.6 0.6 -0.5 -0.4 -0.1 -1.3 0.5 0.2 1.1 -0.1 -0.8 -1.1 -0.6 -1.9 -1.5 -1.0 -1.0 -1.1
Medication: Levothyroxine sodium 0.5 0.8 3.2 0.2 0.3 -0.7 -0.6 -1.5 -0.3 1.0 1.0 -0.6 1.5 -0.4 -0.7 0.7 0.9 -0.7 0.7 -0.3 0.8 1.8 -1.2 -0.0 1.5 0.5 0.4
Sitting height 0.5 3.2 8.2 2.9 1.1 2.1 1.9 1.5 1.9 1.9 -0.8 2.1 -2.1 -0.6 2.4 -1.8 -1.3 -1.7 0.7 2.0 1.6 0.9 1.9 1.5 1.5 2.7 2.1
Chronic bronchitis/emphysema (father) 0.2 0.3 1.5 -0.4 -0.2 -0.2 -0.3 0.3 -0.6 -0.3 0.0 -0.1 -1.2 -1.0 0.0 0.2 0.2 -0.3 0.9 -0.3 -0.3 -0.9 0.5 -0.1 -0.4 -0.5 -0.6
High blood pressure (mother) 0.8 1.1 3.2 1.8 -0.4 1.2 1.3 0.2 1.3 -0.2 -1.6 1.4 0.6 0.3 1.2 -1.4 -1.1 0.1 -0.4 1.3 1.2 -0.5 1.0 1.4 -0.2 1.5 0.6
Body mass index (BMI) 0.2 0.7 4.7 0.6 -1.1 0.1 0.4 -0.9 -0.0 1.1 -0.9 0.4 0.6 0.7 0.0 -0.7 -0.3 -0.5 -0.5 0.4 1.7 0.6 -0.1 2.2 0.6 1.2 0.4
Impedance of leg (left) 0.5 2.3 6.7 -1.1 2.3 -1.1 -1.3 -0.3 -1.5 0.9 2.5 -1.2 -1.7 -2.6 -0.9 1.7 1.7 -1.6 2.6 -1.1 1.2 1.3 0.4 -1.1 1.3 -1.6 0.2
Leg predicted mass (left) 0.2 1.0 2.9 0.8 -1.2 0.6 0.9 -0.4 1.1 -0.7 -1.5 0.8 1.2 1.6 0.4 -1.1 -1.1 1.3 -1.7 0.6 0.1 -1.1 -0.4 1.1 -0.8 0.9 0.1
Trunk fat mass 0.1 0.5 3.7 0.4 -0.0 0.0 0.4 -1.3 -0.1 0.9 -0.7 0.4 0.4 0.5 -0.1 -0.6 -0.4 -0.6 -0.4 0.2 1.7 0.0 -0.2 1.9 0.2 0.7 -0.0
Waist circumference 0.1 0.4 2.9 0.2 -1.2 -0.5 -0.0 -0.9 -0.4 0.5 -0.6 -0.1 0.8 0.5 -0.7 -0.3 -0.1 -0.2 -0.3 -0.2 1.2 0.1 -0.7 1.7 0.1 0.3 -0.1
Number of incorrect matches in round 1.0 1.7 6.5 0.9 1.3 0.8 0.7 0.1 0.3 2.6 -0.2 0.7 -1.8 -0.4 1.1 -0.6 -0.3 -2.3 0.7 1.1 1.7 1.3 1.9 1.5 1.5 1.4 1.6
Past tobacco smoking 0.3 0.5 2.1 0.9 -0.6 1.1 1.0 -0.2 0.8 0.4 -0.9 0.9 0.1 -0.3 0.8 -1.0 -0.7 -0.7 0.4 0.8 -0.3 -0.6 1.5 0.6 0.2 0.3 0.6
Alcohol usually taken with meals 0.3 0.5 2.5 0.1 1.6 0.5 0.3 1.4 0.6 0.2 0.1 -0.1 -1.5 1.0 0.7 -0.2 -0.5 0.1 -0.8 0.3 -0.5 -0.3 -0.2 -0.5 -0.4 0.2 -0.3
Nervous feelings 0.2 0.4 1.0 -0.1 -0.6 -0.6 -0.7 -0.5 -0.1 1.0 0.6 -0.7 -1.0 -0.8 -0.5 0.8 0.8 -0.8 0.8 -0.5 0.4 0.7 -0.1 0.1 0.8 -0.1 0.4
Frequency of tenseness / restlessness in last 2 weeks 2.4 3.8 9.0 2.7 -0.6 2.7 2.7 1.3 2.5 1.4 -2.3 2.6 -1.4 1.3 2.6 -2.6 -2.5 -1.0 -1.0 2.6 0.4 -0.0 1.2 1.9 0.3 3.0 0.5
Hearing difficulty/problems with background noise 1.8 2.9 6.3 2.0 -0.8 2.1 2.2 1.5 2.1 0.3 -2.1 2.1 0.3 2.1 1.9 -2.2 -2.5 0.3 -2.0 2.4 0.2 -1.4 0.5 1.7 -1.1 2.2 -0.2
Hair/balding pattern: Pattern 2 0.8 1.0 2.8 -1.6 -1.7 -1.3 -1.1 -0.9 -1.4 -0.8 0.2 -1.1 0.5 -0.2 -1.6 0.8 0.8 0.5 0.2 -1.3 -0.7 0.2 -0.9 -0.6 -0.1 -1.5 -0.5
Had menopause 1.2 1.5 3.7 -1.8 -0.5 -1.8 -1.7 -0.8 -1.8 0.5 1.1 -1.8 -0.5 -1.0 -1.8 1.5 1.8 -0.6 1.1 -1.9 -0.1 0.7 -0.3 0.0 0.4 -1.5 -0.5
Had other major operations 2.4 3.0 9.5 1.4 -2.0 0.8 0.9 -0.3 0.3 2.5 -0.8 1.1 -0.9 -1.0 0.7 -1.1 0.1 -2.3 1.2 1.0 2.7 2.0 3.0 2.8 2.4 1.1 3.1
Forced vital capacity (FVC) 0.3 1.0 2.1 1.4 0.6 1.3 1.2 1.1 1.4 1.1 -0.8 1.2 -0.3 -0.2 1.4 -1.1 -0.9 -0.5 0.2 1.4 0.4 -0.2 1.2 0.6 0.4 1.4 1.2
Heel bone mineral density (BMD) T-score, automated (right) 1.0 2.4 8.8 0.4 -0.0 1.1 1.1 0.9 1.4 -3.0 -1.1 1.1 2.1 1.4 0.6 -1.1 -1.5 2.9 -1.7 0.9 -2.4 -1.8 -1.5 -1.4 -1.8 -0.1 -1.1
Ever unenthusiastic/disinterested for a whole week 0.3 0.4 1.0 -0.4 -0.1 -0.8 -0.7 -0.6 -1.0 1.0 0.7 -0.7 0.3 -0.4 -0.5 0.8 0.8 -0.9 0.6 -0.6 0.7 0.4 0.5 0.8 0.6 -0.4 -0.1
Qualifications: None of the above 0.2 0.4 1.9 -0.0 -0.7 -0.1 -0.0 -1.4 -0.8 0.8 -0.1 0.0 -0.0 -0.8 -0.3 -0.3 0.4 -0.8 0.8 -0.2 0.6 0.9 -0.2 0.9 0.9 0.4 0.3
Financial difficulties in last 2 years 3.1 4.2 14.7 2.9 0.5 2.3 2.6 2.2 1.9 1.9 -2.1 2.4 -0.4 1.4 1.8 -2.6 -2.3 -1.2 -1.1 2.8 1.1 -0.3 2.1 3.8 0.4 2.9 0.6
Mouth/teeth dental problems 0.3 0.5 2.2 0.6 0.2 0.7 0.8 1.0 0.7 0.8 -0.0 0.5 -1.0 -0.5 0.6 -0.5 -0.3 -0.9 0.6 0.8 0.1 -0.2 1.5 0.6 0.5 -0.1 1.1
Heart attack 0.5 0.7 7.6 -0.4 2.8 -0.4 -0.3 0.2 -1.1 -0.7 0.7 -0.4 0.1 0.9 -0.5 0.3 -0.2 0.5 -0.8 -0.4 -0.3 -0.5 -0.7 -0.0 -0.9 -0.4 -1.4
Allergy 0.2 0.5 2.3 0.2 -1.3 0.3 0.2 1.1 0.3 -1.5 -0.1 0.3 0.2 -0.5 0.1 -0.2 -0.3 0.5 0.4 -0.1 -1.1 -0.9 -0.7 -1.4 -0.8 -0.2 -1.1
Pain all over the body in last month 0.6 0.7 1.8 -1.2 1.2 -1.1 -1.0 -1.3 -1.1 0.5 0.9 -0.8 0.0 -0.1 -1.4 0.9 0.9 -0.3 0.2 -0.9 0.4 0.4 -0.7 0.3 0.4 -1.0 -0.1
Diabetes (self-reported) 0.5 0.8 3.8 -0.2 0.0 0.1 0.2 -0.4 0.2 -1.4 -0.4 0.2 1.4 1.9 -0.0 -0.3 -0.8 1.4 -1.8 0.2 -0.9 -0.5 -1.4 -0.6 -1.1 -0.0 -1.0
Hayfever/allergic rhinitis (self-reported) 0.5 0.6 2.1 -0.2 0.8 -0.4 -0.4 -0.8 -0.6 1.5 0.4 -0.2 -0.2 -0.8 -0.5 0.2 0.7 -1.4 0.9 -0.2 1.3 1.1 0.8 0.8 1.2 -0.0 1.1
Medication: Ramipril 0.1 0.2 0.3 -0.5 -0.4 -0.5 -0.5 -0.3 -0.5 -0.3 0.1 -0.3 0.1 -0.4 -0.5 0.4 0.3 0.1 0.3 -0.5 -0.5 -0.4 -0.4 -0.2 -0.4 -0.5 -0.6
Medication: Simvastatin 0.4 0.6 1.7 -1.3 0.1 -1.1 -1.0 -0.4 -1.0 -0.3 0.3 -1.1 0.7 0.3 -1.3 0.8 0.7 0.1 -0.1 -1.0 0.1 0.2 -1.1 0.1 -0.3 -0.8 -1.1
Fluid intelligence score 0.3 0.5 2.6 -1.1 1.6 -0.4 -0.6 -0.2 -0.1 -0.5 0.6 -0.6 0.2 -0.0 -0.2 0.6 0.2 0.3 -0.0 -0.8 -0.4 -0.7 -0.8 -1.6 -0.8 -0.7 -1.1
Illnesses of siblings 0.2 0.2 1.1 -0.5 0.5 -0.2 -0.2 0.9 0.1 -0.1 0.2 -0.2 0.4 0.8 -0.3 0.3 -0.0 0.7 -0.9 -0.1 -1.1 -0.2 -0.2 -0.6 0.1 -0.5 -0.3
Neuroticism score 0.2 0.5 4.0 -0.2 1.4 -0.5 -0.5 -2.0 -0.6 0.0 0.7 -0.6 0.5 -0.1 -0.2 0.7 0.3 -0.1 0.1 -0.4 0.2 -0.6 -0.5 0.1 -0.7 0.3 -1.0
Weight 0.1 0.6 4.1 0.5 -0.7 -0.2 0.1 -1.1 -0.2 1.2 -0.4 0.2 0.0 0.1 -0.3 -0.4 0.0 -0.8 0.1 -0.0 2.0 0.8 -0.1 1.9 0.9 0.8 0.7
Impedance of arm (right) 0.1 0.4 4.1 -0.1 2.0 0.0 0.1 -0.3 -0.4 0.9 0.6 0.0 -1.2 -0.6 -0.2 0.1 -0.1 -1.2 0.7 -0.1 0.8 0.0 0.4 0.3 0.2 -0.4 -0.4
Arm fat percentage (right) 0.2 0.9 6.6 0.6 -0.5 0.1 0.6 -1.3 -0.1 0.9 -1.1 0.5 0.9 1.1 0.0 -0.9 -0.8 -0.4 -0.9 0.5 1.7 -0.1 -0.3 2.6 -0.1 1.1 -0.3
Trunk fat-free mass 0.0 0.2 2.7 0.2 -1.6 -0.3 -0.2 -0.4 -0.0 -0.1 -0.2 -0.1 0.4 -0.1 -0.3 -0.1 0.2 0.3 -0.0 -0.3 0.9 0.3 -0.1 0.6 0.4 0.2 0.8
Hip circumference 0.4 1.6 7.6 -0.2 -0.0 -1.2 -0.8 -1.9 -1.4 1.8 0.8 -0.9 -0.3 -0.9 -1.2 0.6 1.1 -1.4 1.0 -0.8 2.8 2.0 -0.6 1.4 1.7 0.1 1.1
Time employed in main current job 0.3 0.4 1.7 0.2 -1.3 0.7 0.5 0.9 0.6 -0.6 -0.9 0.6 -0.5 -0.1 0.9 -0.6 -0.5 0.2 0.1 0.4 -0.3 0.4 -0.3 -0.9 0.1 0.6 0.2
Alcohol intake versus 10 years previously 0.3 0.4 1.8 -0.2 -1.4 -0.5 -0.3 0.1 -0.9 0.1 0.0 -0.3 -0.6 -0.2 -1.0 0.2 0.0 -0.3 0.2 -0.3 -0.9 -1.1 -0.5 0.8 -0.8 -0.4 -1.2
Father’s age at death 0.2 0.3 0.9 0.7 0.4 0.5 0.4 -0.1 0.7 0.8 -0.5 0.3 -0.6 -0.5 0.5 -0.3 -0.1 -0.9 0.6 0.4 0.7 0.2 1.0 0.7 0.6 0.7 0.6
Worrier / anxious feelings 0.4 0.7 1.7 -0.7 -0.5 -1.2 -1.2 -0.6 -1.1 0.4 1.2 -1.2 0.3 -0.3 -1.2 1.3 0.9 -0.3 0.4 -1.2 0.3 0.3 -0.8 -0.6 0.1 -0.7 -0.8
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.8 4.3 -0.2 0.1 -0.3 -0.3 -0.9 -0.1 -1.4 0.0 -0.4 2.1 1.0 -0.1 0.2 -0.2 1.4 -1.1 -0.3 -0.9 -1.1 -1.2 -0.6 -1.4 -0.0 -1.4
Falls in the last year 0.5 0.7 2.3 -1.4 -0.4 -1.3 -1.2 -1.1 -1.5 0.2 0.9 -1.1 0.1 0.1 -0.9 1.1 0.9 -0.1 -0.1 -1.1 1.0 0.3 -0.6 0.3 -0.4 -0.6 -0.7
Hair/balding pattern: Pattern 3 0.4 0.7 1.5 0.6 -0.3 0.7 0.8 -0.2 1.2 -0.9 -0.9 1.2 1.1 1.0 0.4 -0.8 -1.1 0.7 -0.9 0.7 -0.3 -1.1 -0.5 0.3 -1.0 0.6 -1.0
Number of live births 0.2 0.2 1.3 -0.4 -0.8 -0.1 0.0 0.2 -0.1 0.5 -0.2 -0.1 -0.3 -0.6 -0.3 -0.0 0.5 -0.4 0.6 0.1 0.2 0.4 0.7 0.5 0.6 -0.7 1.2
Forced expiratory volume in 1-second (FEV1) 0.5 1.7 4.0 1.9 0.2 1.8 1.7 1.2 1.8 1.1 -1.2 1.7 0.0 0.2 2.0 -1.5 -1.4 -0.6 -0.2 1.9 0.5 -0.3 1.4 1.0 0.4 2.0 1.0
Pulse rate 0.1 0.2 1.4 -0.2 -0.8 0.0 -0.2 1.1 -0.2 0.3 0.3 0.0 -0.7 -0.5 0.1 0.3 0.2 -0.2 0.4 -0.1 -0.6 -0.1 0.3 -1.2 0.1 -0.5 0.7
Happiness 0.4 0.5 4.3 -0.0 0.6 -0.2 -0.3 0.4 -0.7 0.8 0.6 -0.3 -0.8 -0.1 0.4 0.2 0.2 -1.3 0.4 -0.3 2.1 0.9 1.0 1.1 0.4 0.9 0.0
Noisy workplace 0.6 0.8 4.1 0.7 -1.5 0.6 0.7 0.3 0.4 -1.1 -1.5 0.4 0.0 0.5 0.3 -0.7 -0.9 0.8 -0.6 0.4 -0.9 -2.0 0.3 0.5 -1.5 0.2 -0.9
Qualifications: A levels/AS levels or equivalent 0.5 1.1 2.9 1.2 -0.4 1.2 1.1 1.7 1.6 0.0 -1.0 0.9 -0.3 1.3 1.3 -1.0 -1.5 0.3 -1.2 1.2 -0.3 -1.1 0.2 0.4 -0.9 1.4 -0.3
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.4 1.4 -0.6 -0.6 -0.9 -0.8 -0.7 -0.6 0.3 0.3 -1.2 0.1 -0.2 -1.1 0.8 0.7 -0.1 0.2 -0.9 0.2 -0.4 0.1 0.4 -0.4 -0.8 -0.4
Mouth/teeth dental problems: Dentures 0.2 0.3 1.5 0.7 -0.7 0.7 0.7 0.4 0.3 -0.7 -1.2 0.8 -0.4 0.0 0.7 -1.0 -0.6 0.1 -0.0 0.3 0.2 0.2 0.2 0.1 -0.1 1.1 -0.1
Asthma 0.5 1.0 4.4 0.1 -1.0 -0.5 -0.5 -0.4 -0.6 2.1 0.8 -0.6 -1.0 -0.9 -0.5 0.6 0.9 -1.8 1.0 -0.3 1.2 1.4 0.9 1.1 1.4 0.1 1.1
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.7 2.4 -0.8 1.2 -1.3 -1.0 -0.1 -1.5 -0.2 1.1 -0.9 0.0 -0.4 -1.5 1.0 0.8 -0.1 0.4 -0.9 0.3 -0.1 -0.6 0.6 -0.1 -1.3 -0.6
Medication: Cholesterol lowering 1.4 2.1 7.5 -0.8 0.1 -0.4 -0.3 0.2 -0.1 -2.5 -0.8 -0.2 2.3 1.6 -0.4 0.1 -0.7 2.2 -1.6 -0.5 -1.5 -2.2 -2.0 -0.7 -2.6 -0.3 -2.7
Depression (self-reported) 1.1 1.4 3.7 0.5 -1.1 0.7 0.7 -1.1 0.7 -1.1 -1.4 0.8 1.6 1.5 0.9 -0.9 -1.3 1.0 -1.4 0.8 -0.1 -1.6 -0.5 1.0 -1.8 1.5 -1.9
Medication: Lansoprazole 2.0 2.3 6.0 -1.7 0.3 -2.0 -2.0 -0.5 -2.1 0.9 2.4 -2.2 -0.7 -0.9 -1.9 2.1 2.0 -0.5 0.9 -1.8 -0.0 1.4 -1.2 -1.0 1.0 -1.9 -0.1
Prospective memory result 0.4 0.5 4.8 0.2 -2.2 0.2 0.4 0.8 0.2 -0.1 -0.7 0.4 0.5 1.1 -0.5 -0.5 -0.5 0.4 -1.0 0.5 -0.6 0.2 -0.9 0.3 0.4 0.0 -0.1
Lung cancer (father) 0.3 0.4 1.1 -0.5 0.8 -0.5 -0.7 -0.8 -0.6 0.5 0.2 -0.4 0.0 -0.7 0.1 0.6 1.0 -0.5 0.7 -0.7 1.1 0.7 0.6 -0.5 0.5 -0.3 0.8
Illnesses of mother 0.5 0.6 2.6 -1.0 1.5 -0.6 -0.8 0.8 -0.6 0.2 1.6 -0.9 -0.4 -0.4 -0.2 1.1 0.9 0.0 0.3 -0.6 0.0 0.7 -0.0 -1.2 0.3 -0.7 0.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.1 3.3 1.8 0.5 1.6 1.4 0.4 1.5 1.0 -0.6 1.4 0.4 -0.0 1.6 -1.1 -1.1 -0.5 -0.0 1.7 -0.0 -0.2 1.1 0.4 0.5 1.5 1.0
Pulse wave Arterial Stiffness index 1.0 1.2 3.0 1.0 -0.6 1.3 1.2 0.7 0.6 -0.5 -1.0 1.4 0.0 1.7 1.4 -1.2 -1.7 0.8 -1.7 1.4 -0.8 -0.6 -0.6 0.1 -1.0 1.4 -0.7
Impedance of arm (left) 0.1 0.4 6.3 -0.1 2.5 0.1 0.1 -0.1 0.1 0.8 0.5 0.1 -0.8 -0.4 -0.1 0.1 -0.1 -0.9 0.5 0.1 0.2 0.2 0.2 -0.2 0.3 -0.4 -0.1
Arm fat mass (right) 0.2 0.6 5.9 0.5 -0.6 -0.1 0.3 -1.2 -0.2 0.9 -0.7 0.3 0.5 0.7 -0.2 -0.6 -0.3 -0.5 -0.5 0.3 1.8 0.4 -0.1 2.4 0.4 0.8 0.2
Trunk predicted mass 0.0 0.2 3.1 0.2 -1.8 -0.3 -0.1 -0.3 0.0 -0.1 -0.2 -0.1 0.3 -0.1 -0.2 -0.1 0.2 0.4 -0.1 -0.2 0.8 0.2 -0.1 0.6 0.4 0.2 0.8
Standing height 0.0 0.4 1.6 -0.0 0.5 -0.4 -0.4 -0.1 -0.1 0.2 0.8 -0.2 -1.3 -1.1 -0.3 0.4 0.5 -0.4 1.0 -0.7 0.8 0.4 0.2 -0.4 0.7 -0.6 0.8
Length of working week for main job 1.4 1.6 3.8 1.3 -1.1 1.6 1.5 1.3 1.6 -0.2 -1.9 1.6 0.5 1.1 1.8 -1.7 -1.6 0.4 -1.0 1.2 0.4 -1.2 0.9 0.9 -1.1 1.6 -0.3
Exposure to tobacco smoke at home 1.2 1.3 3.2 -0.7 -0.5 -1.4 -1.3 -1.2 -1.8 0.8 1.3 -1.3 0.1 -1.1 -1.3 1.3 1.4 -1.2 1.3 -1.1 1.8 1.4 -0.4 1.0 1.0 -0.4 -0.3
Breastfed as a baby 0.1 0.1 0.8 0.0 0.3 0.4 0.1 -0.4 0.3 0.8 -0.2 0.1 -0.2 0.1 0.9 -0.2 -0.2 -0.6 0.0 0.2 0.4 0.2 0.2 -0.3 -0.0 0.7 -0.1
Tense / ‘highly strung’ 0.3 0.4 1.9 0.4 0.1 0.5 0.4 -0.8 0.6 -0.1 -0.5 0.2 0.7 0.6 0.8 -0.3 -0.7 0.3 -0.5 0.4 -0.9 -1.4 -0.2 0.0 -0.9 0.5 -1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.2 4.1 0.0 -1.1 -0.5 -0.5 -1.4 -1.0 1.6 0.3 -0.6 -0.9 -1.4 0.2 0.5 0.8 -2.0 1.5 -0.5 1.9 0.7 1.3 2.0 0.8 0.9 0.2
Hair/balding pattern: Pattern 4 2.6 6.3 13.2 3.2 -0.1 3.5 3.3 3.4 3.0 0.8 -2.9 3.2 -1.6 1.8 3.6 -3.4 -3.1 -0.3 -1.7 3.1 0.2 -1.6 2.8 1.7 -1.0 3.1 0.6
Birth weight of first child 1.3 2.4 8.5 -1.4 -0.3 -1.2 -1.1 -2.3 -1.0 -2.2 0.5 -1.2 2.9 1.3 -1.1 1.2 0.5 2.4 -1.6 -1.1 -1.7 -1.3 -1.6 -1.2 -1.7 -1.5 -1.9
Peak expiratory flow (PEF) 1.1 2.6 5.5 2.1 -0.4 1.9 1.9 2.4 1.7 1.6 -1.6 1.9 -0.8 0.2 2.0 -1.8 -1.5 -1.1 -0.1 2.1 1.4 0.2 2.0 2.1 0.7 2.3 1.3
Pulse wave reflection index 1.1 1.4 3.7 1.5 0.1 1.7 1.6 0.4 1.1 0.2 -1.2 1.9 0.6 1.2 1.8 -1.6 -1.6 0.1 -1.1 1.9 0.2 -0.1 0.6 1.0 -0.2 1.8 -0.1
Ever highly irritable/argumentative for 2 days 0.5 0.7 2.4 1.2 -0.0 0.7 0.8 -0.2 0.4 0.8 -0.6 0.8 0.2 -0.3 0.6 -0.7 -0.3 -0.5 0.2 0.8 1.5 0.6 1.1 1.4 0.8 1.3 0.9
Loud music exposure frequency 0.7 0.8 2.6 0.4 1.1 -0.1 -0.0 -0.3 -0.2 1.0 1.0 0.2 -1.4 -0.9 0.1 0.1 0.5 -0.9 0.8 0.1 1.6 1.5 0.7 0.7 1.4 0.3 1.4
Qualifications: O levels/GCSEs or equivalent 1.5 2.3 6.8 0.3 -1.9 0.9 0.9 1.6 1.3 -1.5 -1.6 0.7 0.9 2.2 1.1 -0.7 -1.7 2.0 -2.3 1.0 -2.1 -2.6 -0.3 -0.4 -2.5 0.4 -1.4
Mouth/teeth dental problems: Bleeding gums 0.1 0.1 0.6 -0.1 0.8 -0.3 -0.2 -0.3 -0.2 0.1 0.5 -0.4 -0.7 -0.1 -0.3 0.2 0.1 0.0 0.0 -0.2 0.7 0.6 -0.5 0.2 0.2 0.4 -0.2
Blood clot in the leg (DVT) 0.2 0.2 0.7 -0.2 -0.4 -0.6 -0.6 -0.2 -0.3 0.8 0.3 -0.4 0.3 0.7 -0.1 0.6 0.5 0.3 -0.8 -0.5 -0.0 0.1 0.4 0.6 0.2 -0.2 0.3
Medication: Paracetamol 0.7 1.2 2.6 -1.1 -1.3 -1.4 -1.3 -0.6 -1.4 -0.2 1.1 -1.2 -1.1 -1.1 -1.6 1.2 1.4 -0.7 1.2 -1.4 1.1 1.0 -0.2 -0.2 0.6 -1.3 0.1
Headache pain in last month 0.2 0.4 2.6 -0.3 -1.6 -0.2 -0.3 -0.2 -0.1 -1.2 -0.1 -0.4 0.7 -0.0 -0.2 0.3 0.1 0.7 -0.0 -0.6 -0.0 -0.5 -0.7 -0.9 -0.7 -0.2 -0.8
Medication for cholesterol, blood pressure or diabetes 1.2 2.1 8.1 0.6 -0.1 0.3 0.2 0.3 0.2 2.6 0.7 -0.0 -2.9 -1.7 0.4 0.1 0.7 -2.3 1.7 0.4 1.5 2.1 1.9 0.6 2.3 0.6 2.3
Glaucoma (self-reported) 3.0 3.5 9.7 2.9 -0.2 2.7 2.7 0.6 2.2 0.3 -2.2 2.9 -0.3 0.5 2.5 -2.7 -2.4 -0.6 -0.3 2.6 0.5 -0.6 1.2 1.9 -0.5 3.1 -0.2
Gout (self-reported) 0.6 0.8 5.7 -0.7 2.4 -0.9 -0.8 -0.3 -1.6 -0.2 1.5 -0.9 0.4 -0.2 -0.9 0.9 0.6 -0.0 0.3 -0.9 0.2 -0.2 -0.6 -0.1 -0.4 -0.8 -0.8
Hypothyroidism/myxoedema (self-reported) 0.5 0.9 2.7 -0.1 0.5 -0.9 -0.9 -1.6 -0.5 1.2 1.2 -1.1 1.6 -0.4 -0.8 1.0 1.1 -0.7 0.7 -0.4 0.4 1.6 -1.2 -0.3 1.2 0.2 0.2
Medication: Amlodipine 0.7 0.9 3.2 -1.3 -1.1 -1.0 -1.1 -0.8 -1.1 -0.9 0.5 -1.0 1.5 0.1 -0.8 0.9 0.6 0.6 -0.0 -1.1 -0.9 -0.1 -1.8 -1.2 -0.5 -0.7 -1.3
Medication: Ventolin 100micrograms inhaler 0.9 1.2 6.5 0.3 0.5 -0.4 -0.2 -0.6 -0.2 2.5 0.6 -0.1 -1.2 -0.8 -0.8 0.3 0.8 -1.7 0.9 -0.1 0.7 1.0 1.7 1.7 1.6 -0.2 1.8
Birth weight 3.3 7.2 15.6 3.5 1.3 3.8 3.8 1.1 3.4 1.2 -3.4 4.0 0.3 2.1 3.8 -3.7 -3.6 -0.6 -1.9 3.7 0.1 -0.9 1.9 2.6 -0.3 3.9 0.4
Chronic bronchitis/emphysema (mother) 0.2 0.2 2.4 0.2 0.9 0.2 0.2 -1.6 -0.0 0.1 0.3 0.1 -0.1 -0.1 -0.0 0.1 -0.2 -0.1 0.1 0.4 -0.6 -0.3 -0.3 -0.5 -0.2 -0.0 -0.3
High blood pressure (siblings) 0.1 0.1 0.7 0.1 -0.7 -0.1 -0.0 -0.4 -0.1 -0.4 0.0 0.0 -0.3 -0.5 0.0 -0.0 0.1 -0.0 0.4 -0.1 0.8 -0.3 0.1 0.2 -0.4 -0.1 -0.0
Forced vital capacity (FVC), Best measure 0.4 1.3 3.5 1.9 0.6 1.6 1.5 0.9 1.7 1.1 -0.6 1.5 -0.2 -0.3 1.8 -1.2 -1.1 -0.6 0.2 1.7 0.3 -0.2 1.3 0.5 0.6 1.6 1.4
Body fat percentage 0.1 0.5 3.5 0.1 0.1 -0.3 0.1 -1.5 -0.4 1.1 -0.5 0.1 0.3 0.4 -0.4 -0.3 -0.1 -0.8 -0.1 0.0 1.7 0.2 -0.3 1.9 0.3 0.5 -0.2
Leg fat percentage (right) 0.3 0.9 5.6 0.1 0.1 -0.4 -0.2 -1.4 -0.9 1.7 0.2 -0.3 -0.4 -0.4 -0.2 0.1 0.4 -1.5 0.7 -0.0 2.4 1.4 0.0 1.7 1.2 0.7 0.5
Arm fat-free mass (right) 0.0 0.2 1.1 0.3 -1.0 -0.1 0.1 -0.1 0.3 -0.1 -0.3 0.1 0.4 -0.0 -0.1 -0.2 0.1 0.4 -0.1 -0.0 0.7 0.2 0.1 0.5 0.5 0.1 1.0
Exposure to tobacco smoke outside home 0.3 0.4 1.3 -0.1 -1.0 0.1 0.1 -0.4 -0.1 -0.8 -0.5 -0.1 0.7 1.1 -0.2 -0.2 -0.5 0.9 -1.1 0.2 -0.5 -0.3 -1.1 -0.5 -0.7 0.3 -0.6
Comparative body size at age 10 0.8 2.2 5.9 2.0 -0.3 1.8 1.7 -0.4 1.8 1.9 -1.9 1.7 -1.1 0.2 1.9 -1.8 -1.0 -1.3 -0.0 1.7 0.8 0.8 1.3 1.4 1.2 2.4 1.8
Number of full brothers 1.8 2.2 5.1 1.9 1.1 2.0 1.9 1.5 1.4 1.1 -1.4 1.9 0.1 1.0 2.3 -1.8 -1.6 -0.4 -0.9 2.2 0.9 0.7 1.3 1.3 0.7 2.2 1.5
Worry too long after embarrassment 0.2 0.4 1.9 1.0 1.4 0.4 0.3 -0.6 0.4 0.4 0.4 0.6 0.5 -0.2 0.6 -0.1 -0.1 -0.6 0.3 0.5 1.2 0.3 0.8 0.6 0.1 1.1 0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 2.5 3.2 8.1 -2.0 -0.6 -2.4 -2.3 -2.9 -2.4 -1.2 2.0 -2.4 1.9 -0.6 -2.1 2.2 1.7 1.1 0.3 -2.3 -1.0 -0.6 -2.2 -0.8 -0.7 -1.9 -1.9
Wheeze or whistling in the chest in last year 0.2 0.3 2.0 0.6 -1.4 0.4 0.5 -0.0 0.1 0.2 -0.7 0.4 -0.6 0.2 0.6 -0.6 -0.5 -0.2 -0.2 0.4 0.0 -0.4 0.5 1.2 -0.2 0.7 0.2
Number of children fathered 0.1 0.1 0.4 0.6 0.6 -0.0 -0.0 -0.3 -0.6 -0.2 0.4 -0.2 0.6 -0.5 -0.1 0.2 0.1 -0.3 0.6 0.0 0.2 -0.1 0.1 0.4 0.2 -0.1 -0.1
Reason for reducing amount of alcohol drunk: Health precaution 1.3 1.6 3.9 -2.0 -0.1 -1.4 -1.4 -1.5 -1.4 -1.8 0.6 -1.5 0.7 -0.4 -1.4 1.4 1.0 1.0 0.3 -1.5 -0.1 -0.8 -1.0 -1.5 -1.3 -1.6 -1.3
Age at first live birth 0.6 1.1 3.8 0.6 -0.9 0.1 -0.0 0.6 0.0 1.8 0.6 -0.1 -1.8 -1.1 0.5 0.4 0.5 -1.4 1.1 0.3 1.1 1.6 1.1 0.4 1.8 0.6 1.9
Pulse wave peak to peak time 0.9 1.1 3.0 -0.8 0.7 -1.3 -1.2 -0.6 -0.5 0.5 1.1 -1.4 -0.1 -1.7 -1.3 1.1 1.6 -0.8 1.6 -1.3 0.7 0.5 0.6 -0.0 1.0 -1.4 0.7
Health satisfaction 0.4 0.5 2.4 0.1 -1.5 -0.2 -0.1 -0.1 -0.7 0.7 -0.1 0.1 -0.9 -0.7 -0.3 -0.1 0.4 -1.0 0.8 -0.2 1.3 0.8 0.8 1.1 0.9 0.1 0.8
Shortness of breath walking on level ground 1.5 1.7 5.7 -1.2 -0.7 -0.7 -0.6 -0.3 -0.4 -2.1 -0.3 -0.7 1.9 1.2 -1.1 0.5 -0.1 2.0 -1.4 -0.8 -1.7 -1.8 -1.6 -0.7 -2.1 -1.2 -2.4
Qualifications: College or University degree 0.2 0.5 1.5 0.5 -0.9 0.6 0.4 1.0 1.1 0.9 -0.1 0.2 -0.8 -0.5 0.9 -0.2 0.0 -0.8 0.6 0.4 0.2 0.3 1.1 -0.3 0.9 -0.2 1.2
Eye problems/disorders: None of the above 0.9 1.0 4.2 1.1 -1.1 1.2 1.3 1.7 1.0 0.7 -1.1 1.2 -0.7 -0.1 1.1 -1.1 -0.6 -0.7 0.2 1.1 0.4 -0.4 2.1 1.1 0.5 0.5 1.1
Mouth/teeth dental problems: Loose teeth 0.3 0.4 1.3 -0.6 0.3 -0.7 -0.7 -1.0 -1.1 0.4 0.9 -0.8 0.4 -0.0 -0.8 0.7 0.6 -0.3 0.1 -0.6 0.1 0.4 -0.2 0.5 0.2 -0.8 -0.3
Emphysema/chronic bronchitis 0.6 0.7 2.8 -0.2 -0.0 -0.3 -0.0 -0.4 0.3 -1.1 -0.8 0.2 1.0 1.2 -0.5 -0.3 -0.4 1.7 -1.4 0.0 -0.9 -1.3 -0.9 -0.1 -1.3 -0.6 -0.5
Medication for pain relief, constipation, heartburn 0.9 1.6 4.3 1.7 -0.4 1.7 1.4 0.2 1.8 1.4 -0.9 1.3 -1.1 -0.1 2.1 -1.3 -0.9 -0.7 -0.0 1.6 0.1 0.8 1.6 -0.0 1.1 1.7 2.1
Neck or shoulder pain in last month 0.3 0.5 1.5 0.1 0.9 -0.5 -0.5 -1.0 -1.2 0.9 1.2 -0.6 0.4 -0.8 -0.7 0.7 0.4 -1.1 0.9 -0.1 0.2 0.4 -0.3 0.4 0.4 -0.1 -0.4
Medication: Blood pressure 1.1 2.0 7.3 -0.8 0.6 -0.4 -0.3 -0.6 -0.5 -2.7 -0.1 -0.2 2.5 1.4 -0.6 0.2 -0.5 2.2 -1.5 -0.6 -1.9 -1.8 -2.1 -1.0 -2.1 -0.9 -2.3
Angina (self-reported) 0.4 0.5 2.1 -0.7 1.5 -0.9 -0.7 -0.9 -1.2 -0.4 0.9 -0.7 0.2 -0.2 -1.2 0.7 0.6 0.0 0.2 -0.8 -0.0 0.2 -0.6 -0.0 -0.2 -0.8 -0.5
Migraine (self-reported) 0.6 0.8 1.7 0.8 -0.5 1.1 1.1 1.0 0.8 0.7 -0.9 1.0 0.3 1.1 1.3 -0.8 -1.1 -0.3 -0.9 1.3 0.8 0.1 0.4 1.1 0.0 1.3 0.1
Medication: Ibuprofen 1.5 1.8 5.0 -1.4 1.2 -2.0 -1.7 -0.9 -2.1 -0.4 1.8 -1.5 0.0 -1.1 -2.2 1.7 1.6 0.1 1.0 -1.5 0.3 0.6 -1.1 -0.3 0.4 -2.1 -0.1
Medication: Allopurinol 1.5 2.0 5.1 -1.5 1.6 -1.9 -1.8 -1.8 -2.2 -0.7 1.7 -2.0 0.8 -1.0 -1.8 1.7 1.7 0.4 0.8 -1.8 0.8 0.5 -1.1 -0.9 0.2 -1.6 -0.3
Medication: Omeprazole 1.7 2.1 4.8 -1.5 0.6 -1.8 -1.7 -1.6 -1.7 -1.6 1.2 -1.7 0.8 -0.7 -2.2 1.6 1.4 1.1 0.5 -1.9 -0.9 0.0 -2.1 -1.6 -0.1 -2.0 -0.9
Medication: Seretide 50 evohaler 0.4 0.4 2.3 0.6 1.3 0.2 0.4 -0.7 -0.2 1.3 -0.2 0.2 -0.3 0.2 -0.2 -0.4 -0.1 -0.9 -0.0 0.4 0.6 0.5 0.8 1.5 0.7 0.3 0.6
Mean time to correctly identify matches 1.5 2.8 7.6 1.9 -1.6 2.5 2.3 0.8 2.4 0.6 -2.7 2.4 -0.7 0.8 2.4 -2.4 -2.1 -0.4 -0.7 2.1 -0.3 -0.7 0.5 0.3 -0.4 2.8 0.2
Heart disease (mother) 0.3 0.4 2.4 -0.6 1.3 -0.5 -0.6 -1.5 -0.4 -0.1 0.4 -0.6 1.0 0.4 -0.4 0.7 0.3 0.1 -0.3 -0.5 -0.3 -0.4 -0.7 -0.4 -0.5 -0.5 -0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.3 2.7 5.9 -1.6 0.3 -2.2 -2.1 -1.3 -2.4 -0.5 2.1 -2.3 -0.6 -2.2 -2.0 2.2 2.3 -0.3 2.1 -2.2 1.8 1.1 -0.5 -0.8 0.7 -1.3 0.4
Whole body fat mass 0.1 0.5 4.1 0.5 -0.5 0.0 0.4 -1.2 -0.1 0.8 -0.8 0.4 0.4 0.7 -0.1 -0.7 -0.4 -0.4 -0.5 0.3 1.6 0.1 -0.2 2.0 0.2 0.7 0.1
Leg fat mass (right) 0.1 0.5 3.7 0.3 -0.4 -0.2 0.1 -1.1 -0.4 0.9 -0.4 0.0 0.4 0.6 -0.1 -0.3 -0.1 -0.5 -0.4 0.1 1.8 0.5 -0.2 1.9 0.4 0.8 0.1
Arm predicted mass (right) 0.0 0.2 1.2 0.1 -0.8 -0.4 -0.2 -0.6 0.0 -0.0 0.1 -0.2 0.4 -0.1 -0.3 0.1 0.5 0.4 -0.1 -0.3 0.7 0.5 -0.1 0.5 0.6 -0.0 1.1
Pulse rate, automated reading 0.9 3.0 6.2 2.1 -2.0 2.1 1.9 1.5 1.6 1.5 -1.6 2.1 -1.9 -0.9 2.2 -1.9 -1.1 -1.6 0.9 1.8 1.4 0.8 2.4 0.9 1.4 1.8 2.5
Alcohol intake frequency. 0.5 1.2 5.3 1.3 -1.2 0.9 1.1 0.2 -0.1 0.7 -0.5 0.9 -1.4 -1.3 0.4 -1.1 -0.5 -1.7 1.4 0.8 0.6 -0.5 1.8 2.3 0.1 0.8 0.3
Comparative height size at age 10 0.1 0.6 1.7 -0.7 -0.9 -0.7 -0.7 -0.1 -0.5 0.7 0.6 -0.6 -1.3 -1.2 -0.5 0.5 0.6 -0.7 1.1 -0.9 1.0 0.8 -0.7 -0.6 0.7 -0.3 0.1
Number of full sisters 2.0 2.4 4.6 -2.1 -0.2 -2.1 -1.9 -1.9 -1.8 -1.5 1.0 -2.0 0.6 -0.7 -2.1 1.7 1.5 1.0 0.5 -2.1 -0.5 -0.6 -2.1 -1.4 -0.8 -2.0 -1.8
Suffer from ‘nerves’ 1.3 2.0 6.8 -0.2 -0.6 -0.8 -0.8 -0.6 -1.0 1.9 1.0 -0.8 -2.6 -2.2 -0.3 0.8 1.4 -2.1 2.2 -0.8 2.2 1.8 0.9 0.6 2.0 -0.1 1.6
Overall health rating 0.2 0.3 2.5 0.2 -1.0 -0.2 -0.0 -1.6 -0.6 -0.3 -0.6 -0.1 0.8 -0.5 -0.2 -0.2 0.0 -0.3 0.5 -0.1 0.6 -0.1 -0.2 1.4 -0.2 0.5 -0.4
Chest pain or discomfort 1.1 1.6 5.3 -0.8 0.3 -1.5 -1.5 -2.3 -1.4 0.9 1.8 -1.8 0.1 -1.0 -1.4 1.6 1.7 -0.7 0.9 -1.4 1.3 1.7 -0.8 -0.4 1.2 -0.5 0.4
Had major operations 0.9 1.1 2.6 -0.8 -0.9 -1.4 -1.4 -1.4 -1.2 0.1 0.9 -1.3 0.3 -0.8 -1.3 1.2 1.6 0.2 0.6 -1.4 0.5 1.3 -0.4 -0.5 1.0 -0.8 0.9
Age at last live birth 3.1 4.5 14.2 1.8 -0.6 0.8 0.8 1.7 0.0 3.4 0.3 0.6 -3.4 -2.3 1.1 -0.4 0.5 -3.3 2.4 1.1 2.1 2.6 3.0 1.9 3.5 1.0 3.8
Family relationship satisfaction 1.7 2.1 6.7 1.5 -0.2 1.2 1.0 1.3 0.3 1.9 -0.3 1.0 -1.9 -1.3 1.4 -1.1 -0.1 -2.4 1.6 0.8 1.7 1.6 2.6 1.4 1.9 1.5 1.9
Leg pain on walking 0.9 1.1 3.9 -0.2 -2.0 -1.1 -0.9 -1.0 -1.0 0.8 0.6 -0.8 -0.4 -1.3 -1.1 0.7 1.4 -1.0 1.4 -0.9 1.0 1.6 0.2 0.8 1.6 -0.7 0.9
Qualifications: NVQ or HND or HNC or equivalent 0.6 0.7 2.9 -0.3 1.7 -0.4 -0.3 -0.1 -0.1 -1.2 0.6 -0.3 1.6 0.7 -0.6 0.5 -0.1 1.2 -0.8 -0.3 -1.1 -0.8 -0.9 -0.6 -1.1 -0.4 -0.9
Commuting to job workplace: Car/motor vehicle 1.0 1.1 2.4 1.2 -1.3 1.4 1.4 -0.5 1.1 -0.7 -1.3 1.4 1.1 0.7 1.5 -1.4 -1.5 0.5 -0.7 1.3 -0.4 -1.2 0.2 0.2 -1.0 1.0 -0.4
Illness, injury, bereavement, stress in last 2 years 0.7 0.9 4.4 0.7 -0.6 1.0 0.7 1.8 1.2 0.1 -0.3 1.0 -2.1 -0.5 1.4 -0.7 -0.3 -0.1 0.4 0.6 -0.4 0.6 0.6 -1.3 0.7 0.7 1.3
Medication: Aspirin 1.3 1.8 7.5 -0.9 1.0 -0.7 -0.5 -0.1 -0.7 -2.3 -0.3 -0.5 2.7 1.3 -0.8 0.3 -0.1 1.8 -1.3 -0.8 -1.2 -2.1 -1.2 0.4 -2.2 -0.9 -2.3
Supplements: Vitamin C 2.6 3.1 6.3 -2.1 -0.5 -2.2 -2.3 -2.2 -2.4 1.2 1.9 -2.3 -0.5 -1.6 -1.7 2.2 2.5 -1.6 1.8 -2.2 1.6 1.9 -0.3 -0.6 1.4 -1.7 0.4
Knee pain experienced in last month 0.5 0.8 2.0 -0.7 0.3 -1.0 -0.8 -1.1 -1.0 -1.0 0.2 -0.6 0.7 0.4 -1.2 0.6 0.3 1.1 -0.6 -0.9 -0.7 -1.1 -1.3 -0.4 -1.2 -1.0 -1.4
Hypertension (Self-reported) 0.1 0.3 0.9 -0.4 -0.9 -0.6 -0.5 -0.3 -0.7 -0.1 0.3 -0.6 0.2 -0.8 -0.7 0.3 0.6 -0.3 0.8 -0.6 0.9 1.0 -1.0 -0.3 0.7 -0.1 0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.5 2.9 9.4 -1.5 1.4 -2.3 -2.2 -0.0 -2.3 1.0 3.1 -2.3 -1.4 -1.4 -2.2 2.5 2.3 -1.0 1.4 -2.0 0.5 1.4 -0.9 -0.5 1.2 -1.8 0.0
Illnesses of father: Heart disease 0.8 1.1 2.4 1.5 -1.2 1.5 1.5 0.7 1.2 0.4 -1.1 1.4 -1.0 0.6 1.2 -1.5 -1.3 -0.5 -0.4 1.4 0.2 0.2 0.3 0.6 0.2 1.4 0.4
Illnesses of siblings: Diabetes 0.3 0.4 1.6 -0.5 -0.5 -0.5 -0.6 -1.2 -0.4 0.1 0.4 -0.6 0.9 -0.6 -0.6 0.5 0.7 -0.2 0.6 -0.7 0.2 0.7 -1.2 -1.1 0.2 0.0 -0.1
Smoking status: Previous 1.2 1.8 4.0 -1.8 0.7 -2.0 -1.9 -0.5 -1.6 -0.0 1.9 -1.8 -0.7 -0.4 -1.9 1.9 1.7 0.3 0.3 -1.8 0.8 1.2 -1.7 -1.1 0.4 -1.3 -0.5
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.3 1.0 0.5 0.1 0.4 0.3 -0.1 0.4 0.8 0.3 0.0 -1.0 -0.5 0.5 -0.1 0.0 -0.5 0.4 0.2 0.4 0.6 0.7 -0.4 0.7 0.2 1.0
Whole body fat-free mass 0.1 0.3 2.5 0.4 -1.6 -0.0 0.2 -0.4 0.4 -0.4 -0.6 0.2 0.8 0.5 -0.1 -0.4 -0.2 0.9 -0.7 -0.0 0.4 -0.3 -0.3 0.7 -0.1 0.3 0.5
Leg fat-free mass (right) 0.2 1.1 2.8 1.0 -1.4 0.7 1.0 -0.3 1.3 -0.7 -1.6 1.0 1.2 1.5 0.5 -1.3 -1.2 1.3 -1.7 0.7 -0.0 -1.1 -0.3 1.1 -0.7 1.0 0.2
Arm fat percentage (left) 0.2 0.8 5.5 0.7 -0.2 0.3 0.7 -1.0 0.3 1.0 -1.2 0.6 0.8 1.1 0.2 -1.0 -0.8 -0.4 -0.9 0.7 1.6 0.1 -0.2 2.4 0.1 1.2 -0.0
Average weekly red wine intake 1.7 2.5 6.7 1.3 0.0 2.0 1.8 2.1 1.7 0.1 -1.9 1.7 -0.6 2.6 2.4 -1.9 -2.2 0.4 -2.3 1.6 -0.1 -0.3 0.1 0.1 -0.9 2.3 -0.5
Handedness (chirality/laterality): Left-handed 0.5 0.6 2.8 -0.9 0.2 -0.8 -1.0 -1.7 -0.9 -0.4 0.8 -1.2 0.8 -0.2 -0.6 1.0 0.9 0.2 0.2 -0.8 -0.0 0.6 -0.6 -1.1 0.2 -0.8 -0.3
Mood swings 0.5 1.0 5.5 -0.9 0.4 -1.3 -1.3 -2.4 -1.3 -0.1 1.1 -1.4 0.4 -0.6 -0.9 1.4 1.0 -0.2 0.6 -1.0 0.8 -0.1 -0.6 0.3 -0.3 -0.4 -1.2
Loneliness, isolation 0.1 0.2 1.3 -0.2 0.2 -0.4 -0.3 -0.4 -0.7 0.4 0.1 -0.3 -0.4 -0.3 -0.6 0.1 0.4 -0.7 0.4 -0.6 1.2 0.2 0.3 0.7 0.1 -0.0 -0.4
Long-standing illness, disability or infirmity 0.9 1.3 7.3 -0.7 0.2 -0.3 -0.3 -1.8 -0.2 -1.4 -0.5 -0.0 2.7 1.1 -0.4 0.1 -0.2 1.5 -1.1 -0.5 -1.6 -1.0 -2.0 -1.0 -1.4 -0.3 -1.6
Ever had bowel cancer screening 0.8 0.9 2.5 0.6 -1.2 1.3 1.2 0.4 1.2 1.0 -1.5 0.9 -0.8 0.9 1.4 -1.2 -1.2 -0.6 -0.6 1.2 0.2 0.1 0.1 0.2 -0.1 1.6 0.2
Diabetes diagnosed by doctor 0.5 0.8 3.6 -0.3 -0.0 0.1 0.2 -0.7 0.1 -1.4 -0.6 0.4 1.4 1.9 0.0 -0.4 -0.9 1.2 -1.7 0.3 -0.8 -0.4 -1.4 -0.5 -1.0 0.2 -0.9
Ever had stillbirth, spontaneous miscarriage or termination 0.3 0.3 1.0 0.3 -0.9 0.8 0.8 -0.4 0.5 0.2 -1.0 0.8 -0.7 0.4 0.6 -0.9 -0.8 -0.2 -0.3 0.7 0.1 -0.1 -0.1 0.1 -0.1 1.0 0.3
Friendships satisfaction 0.9 1.1 3.9 0.3 -1.7 0.1 -0.0 0.4 -0.2 0.8 -0.2 -0.0 -1.0 -1.5 0.4 -0.3 0.7 -1.5 1.6 -0.3 2.0 1.8 1.3 0.4 1.8 0.5 1.4
Qualifications: nursing, teaching 0.4 0.6 3.0 -0.8 -0.7 -0.8 -0.9 0.1 -0.6 -0.0 0.8 -0.9 -1.7 -1.2 -0.5 0.9 0.8 -0.6 1.2 -0.8 1.0 0.5 -0.1 -0.3 0.3 -0.4 -0.1
Commuting to job workplace: Walk 1.4 1.5 5.5 -1.1 -0.6 -0.8 -1.0 -0.6 -1.0 1.7 0.2 -0.9 -1.9 -1.3 -0.9 0.8 1.4 -1.8 1.5 -0.9 1.5 2.3 0.7 0.0 1.9 -0.1 1.2
Eye problems/disorders: Cataract 2.1 2.4 5.3 -2.2 -0.1 -2.0 -2.1 -1.5 -1.7 -1.4 1.1 -2.2 0.8 0.1 -1.4 1.9 1.4 1.5 -0.4 -2.3 -1.1 -0.2 -2.2 -2.1 -1.0 -1.3 -1.6
Mouth/teeth dental problems: Mouth ulcers 0.8 1.3 3.5 -1.1 0.3 -1.6 -1.6 -1.0 -1.8 -0.1 1.9 -1.4 1.0 -0.7 -1.7 1.7 1.4 -0.0 0.6 -1.5 0.2 0.1 -1.0 -0.4 -0.2 -1.1 -1.1
Medication for cholesterol 0.1 0.2 0.9 -0.1 0.7 0.2 0.1 0.6 0.2 -0.5 0.2 -0.0 -0.3 0.2 0.5 0.1 -0.3 0.5 -0.3 -0.1 -0.8 -0.9 0.3 -0.4 -0.7 -0.3 -0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.2 1.2 -0.4 -0.7 0.0 -0.1 0.7 0.1 -0.2 -0.3 0.1 -1.1 0.4 0.3 0.1 0.0 0.5 -0.4 0.1 0.0 0.2 -0.3 -0.8 -0.2 -0.1 0.3
Back pain experienced in last month 0.7 1.0 3.5 1.4 -0.3 1.5 1.3 0.4 0.7 0.9 -1.3 1.5 -0.3 0.3 1.7 -1.4 -1.2 -0.5 -0.3 1.3 0.3 -0.4 0.5 0.5 -0.3 1.9 0.1
Mineral and other dietary supplements 0.6 0.8 2.7 0.9 -0.8 0.5 0.4 1.0 0.3 0.1 0.3 0.2 -0.6 -1.4 1.0 -0.3 0.1 -0.7 1.3 0.4 1.6 0.9 1.4 0.5 1.0 0.7 1.4
Breast cancer (self-reported) 1.0 1.1 3.0 1.6 -0.0 1.3 1.4 0.6 1.1 0.4 -1.2 1.6 -0.2 0.5 1.1 -1.5 -1.2 -0.4 -0.4 1.5 0.3 -0.6 1.5 1.7 0.1 0.9 1.0
Asthma (self-reported) 0.5 1.1 4.9 0.2 -0.8 -0.4 -0.4 -0.3 -0.6 2.2 0.8 -0.5 -1.1 -1.0 -0.3 0.5 0.8 -1.9 1.1 -0.2 1.4 1.4 1.1 1.2 1.5 0.2 1.3
Osteoporosis (self-reported) 0.5 0.7 2.4 0.1 -0.9 0.5 0.7 0.2 0.5 -1.6 -1.2 1.0 0.5 1.0 0.1 -0.9 -1.1 0.9 -0.9 0.3 -1.1 -0.6 -0.7 -0.1 -1.0 0.0 -0.9
Osteoarthritis (self-reported) 1.0 1.2 2.7 -1.5 -0.5 -1.4 -1.6 -1.6 -1.4 0.4 1.2 -1.2 -0.7 -1.1 -1.0 1.5 1.6 -0.4 1.0 -1.4 0.2 0.9 -0.6 -1.2 0.6 -0.9 -0.2
Medication: Aspirin 1.1 1.4 6.5 -0.9 1.4 -0.8 -0.6 -0.1 -0.7 -2.0 0.0 -0.6 2.6 1.1 -0.7 0.4 0.1 1.7 -1.1 -0.9 -1.1 -1.6 -1.2 0.1 -1.8 -0.8 -1.9
Medication: Gliclazide 0.2 0.3 1.2 0.6 -0.3 -0.1 0.1 -0.3 -0.2 0.4 0.1 0.1 -0.4 -0.8 -0.4 -0.1 0.1 -0.8 0.9 0.0 0.4 -0.0 1.1 1.0 0.4 -0.5 0.5
Illnesses of father: None of the above (group 1) 0.5 0.6 1.8 -1.3 0.1 -1.1 -1.1 -0.5 -0.7 -0.2 0.8 -1.0 0.4 -0.4 -0.9 1.0 1.1 0.3 0.3 -1.3 -0.1 0.3 -0.1 -0.8 -0.0 -1.2 0.0
Smoking status: Current 3.5 5.6 11.2 2.7 0.0 2.9 3.0 2.0 2.6 -1.0 -3.2 2.8 1.7 2.5 2.7 -3.1 -3.4 1.3 -2.5 2.9 -1.8 -2.9 0.7 1.8 -2.2 2.4 -1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 2.0 0.3 1.1 -0.1 -0.1 -0.5 -0.3 1.0 1.0 -0.1 1.4 -0.2 0.1 0.3 0.3 -0.7 0.3 0.5 0.8 0.7 0.4 0.7 1.0 0.2 0.6
Whole body water mass 0.1 0.4 2.7 0.5 -1.6 0.0 0.3 -0.3 0.5 -0.4 -0.7 0.3 0.8 0.6 -0.0 -0.5 -0.3 0.9 -0.7 0.1 0.5 -0.3 -0.2 0.8 -0.1 0.4 0.6
Leg predicted mass (right) 0.2 1.0 2.7 0.9 -1.3 0.6 0.9 -0.3 1.2 -0.7 -1.5 0.9 1.2 1.5 0.4 -1.2 -1.2 1.4 -1.6 0.6 -0.0 -1.1 -0.4 1.0 -0.7 0.9 0.1
Arm fat mass (left) 0.2 0.8 5.8 0.7 -0.6 0.2 0.6 -1.1 0.1 1.1 -0.9 0.5 0.6 0.8 0.1 -0.8 -0.5 -0.5 -0.6 0.5 1.9 0.4 -0.0 2.4 0.4 1.2 0.3
Number of self-reported non-cancer illnesses 1.0 1.7 5.4 -1.5 0.9 -1.6 -1.7 -2.3 -2.3 0.2 1.6 -1.4 -0.0 -0.6 -1.6 1.7 1.4 -0.6 0.8 -1.3 0.6 1.2 -1.8 -0.8 0.4 -0.6 -1.0
Average weekly champagne plus white wine intake 0.3 0.4 1.7 -0.1 1.3 -0.0 -0.1 -0.1 -0.0 1.2 0.4 -0.1 -0.9 -0.4 0.2 0.2 0.3 -0.7 0.4 0.1 0.9 1.2 -0.1 -0.4 1.3 0.1 1.0
Miserableness 0.2 0.4 2.0 0.7 1.4 0.5 0.4 -1.3 0.3 0.5 -0.3 0.4 -0.5 -0.1 0.7 -0.2 -0.3 -0.2 0.0 0.5 0.7 -0.3 0.3 0.4 -0.1 1.1 0.2
Guilty feelings 0.4 0.7 1.9 0.9 -0.0 1.0 0.9 0.6 0.8 0.3 -1.0 0.9 -0.4 0.7 1.0 -0.9 -0.9 -0.2 -0.6 0.9 0.3 -1.0 1.0 1.1 -0.9 1.4 -0.3
Wears glasses or contact lenses 0.5 0.6 1.8 0.6 -0.9 0.8 0.7 0.1 1.3 0.4 -1.2 1.0 1.4 1.0 0.7 -0.9 -0.7 0.3 -0.9 0.7 -0.8 -0.4 0.0 0.1 -0.2 0.8 0.2
Ever taken oral contraceptive pill 2.0 2.2 7.5 -0.6 0.8 0.0 -0.1 -0.9 0.2 -2.7 -0.4 0.3 1.6 2.2 -0.3 -0.1 -0.8 2.6 -2.3 -0.1 -2.1 -1.7 -1.9 -1.9 -2.2 -0.5 -2.0
Hearing aid user 0.4 0.5 1.7 -0.3 1.2 -0.3 -0.3 0.4 -0.1 -1.1 0.5 -0.1 0.7 1.0 -0.4 0.2 -0.3 1.3 -1.1 -0.0 -0.9 -0.4 -1.1 -0.8 -0.7 -0.6 -0.8
Mother’s age at death 0.4 0.5 2.3 -0.4 -0.4 -0.8 -0.8 -1.5 -0.4 0.3 0.4 -0.6 -0.0 -0.9 -0.9 0.8 0.9 -0.7 1.0 -0.8 0.0 0.6 0.0 -0.3 0.6 -0.7 0.1
Financial situation satisfaction 0.4 0.5 2.7 1.0 -0.2 0.6 0.6 0.9 0.2 0.4 -0.3 0.7 -0.5 -0.5 0.6 -0.6 -0.3 -0.6 0.4 0.6 1.6 0.2 1.2 1.2 0.5 1.0 0.5
Tinnitus: Yes, now most or all of the time 1.4 1.6 3.6 -1.1 0.4 -1.9 -1.7 -1.4 -1.9 0.7 1.9 -1.9 -0.9 -0.8 -1.9 1.6 1.5 -0.5 0.7 -1.6 0.6 1.0 -1.0 -0.1 0.7 -1.2 0.1
Commuting to job workplace: Public transport 0.7 0.9 2.6 -1.2 0.6 -1.0 -1.0 1.5 -0.7 0.3 0.9 -1.4 -1.6 -0.3 -1.4 1.0 0.8 -0.2 0.4 -1.1 -0.4 0.5 -1.2 -1.0 0.4 -1.1 -0.3
Eye problems/disorders: Glaucoma 1.8 2.2 7.5 2.0 -0.4 1.9 1.9 0.5 1.3 0.7 -1.3 2.1 -0.9 0.1 2.0 -1.9 -1.7 -1.0 0.1 2.1 1.7 0.1 1.2 1.9 -0.0 2.7 0.0
Medication: Blood pressure 0.4 0.8 3.4 -0.2 -0.5 -0.3 -0.4 -0.4 -0.2 1.7 0.1 -0.4 -0.8 -1.0 -0.2 0.2 0.8 -1.4 1.0 -0.2 1.3 1.8 0.3 0.2 1.7 0.3 1.3
Pain type(s) experienced in last month: Hip pain 1.1 1.4 4.1 -0.4 -0.2 0.4 0.3 -0.5 0.5 -0.8 -1.3 0.4 1.4 1.8 0.5 -0.4 -1.0 1.5 -1.9 0.3 -2.0 -1.7 -1.5 -0.9 -2.0 0.4 -1.9
Supplements: Fish oil (including cod liver oil) 0.6 0.7 3.0 -0.9 -0.4 -0.7 -0.6 -0.7 -0.2 -0.1 -0.2 -0.4 1.0 1.4 -0.9 0.5 0.1 0.7 -1.3 -0.5 -1.7 -0.7 -1.5 -0.6 -0.9 -0.6 -1.3
High cholesterol (Self-reported) 0.1 0.2 1.9 -0.1 -0.3 -0.2 0.0 0.5 -0.4 -0.2 -0.7 0.3 0.1 -0.3 -0.4 -0.3 0.0 -0.3 0.4 -0.2 1.2 -0.2 0.4 1.4 -0.3 0.3 -0.5
Medication: Bendroflumethiazide 1.7 2.6 7.0 1.8 0.4 2.3 2.1 0.8 2.6 0.7 -1.9 2.1 0.8 2.1 2.5 -2.1 -2.0 0.2 -1.9 2.0 0.0 -0.1 0.0 0.1 -0.2 2.4 0.5
Medication: Paracetamol 1.7 2.6 5.6 -1.9 -0.3 -2.3 -2.2 -1.6 -2.1 -1.1 2.0 -2.1 -0.4 -1.1 -2.4 2.2 2.1 0.1 1.1 -2.2 0.7 1.1 -1.4 -1.2 0.4 -2.2 -0.6
Medication: Lisinopril 1.6 2.1 4.8 -2.2 0.2 -2.1 -2.1 -1.0 -1.9 -0.7 1.4 -2.0 1.3 -0.1 -1.8 1.9 1.7 1.0 -0.1 -2.1 -0.3 0.4 -1.9 -1.3 -0.4 -1.4 -0.8
Medication: Atorvastatin 0.6 0.8 3.6 0.4 0.7 -0.0 -0.1 0.5 -0.4 0.6 0.3 0.2 -1.1 -1.8 0.4 0.1 0.6 -1.4 1.8 -0.1 1.9 0.6 1.1 0.5 0.7 0.7 1.0
Illnesses of father: High blood pressure 0.4 0.5 3.9 1.0 -2.0 0.6 0.8 0.3 0.7 -1.2 -0.8 0.5 0.4 -0.3 0.4 -0.8 -0.7 0.5 0.2 0.6 -0.3 -0.8 0.4 0.8 -0.3 0.3 0.3
Alcohol drinker status: Never 0.1 0.1 0.6 -0.5 0.1 -0.2 -0.3 0.3 -0.3 -0.0 0.2 -0.2 -0.4 -0.4 -0.1 0.2 0.3 -0.1 0.4 -0.4 -0.7 -0.4 0.1 -0.1 -0.2 -0.8 -0.1
Ever smoked 0.2 0.4 1.2 -0.8 0.5 -0.9 -0.9 0.0 -0.9 -0.0 0.9 -1.0 -0.1 -0.0 -0.5 0.9 0.7 0.2 -0.1 -0.7 0.3 0.7 -1.1 -0.6 0.1 -0.2 -0.4
Basal metabolic rate 0.1 0.3 1.9 0.6 -1.4 0.0 0.3 -0.6 0.4 -0.0 -0.7 0.3 0.6 0.5 -0.0 -0.6 -0.3 0.5 -0.6 0.1 0.9 -0.1 -0.2 1.2 0.1 0.6 0.7
Leg fat percentage (left) 0.2 0.7 4.4 0.2 -0.0 -0.3 -0.1 -1.4 -0.7 1.6 0.0 -0.1 -0.3 -0.4 -0.0 -0.0 0.3 -1.4 0.6 0.0 2.1 1.1 -0.0 1.6 1.0 0.8 0.3
Arm fat-free mass (left) 0.0 0.2 1.3 0.1 -1.1 -0.4 -0.2 -0.8 -0.2 0.2 -0.1 -0.1 0.2 -0.1 -0.3 -0.0 0.3 0.2 -0.0 -0.4 1.1 0.3 -0.1 0.8 0.4 0.2 0.8
Number of operations (self-reported) 1.0 1.5 5.6 0.8 -0.5 0.6 0.6 0.4 0.1 2.2 -0.6 0.4 -1.6 -0.3 0.9 -0.7 -0.0 -1.8 0.5 0.8 2.4 1.7 1.9 1.6 1.4 1.4 1.9
Average weekly beer plus cider intake 1.1 1.7 10.6 -0.4 -0.9 -0.1 -0.0 -0.0 -0.1 -2.2 -0.6 0.1 3.3 1.1 -0.2 -0.2 -0.6 1.8 -1.1 -0.2 -1.0 -2.0 -1.1 -0.1 -2.2 -0.0 -2.4
Irritability 1.2 2.0 4.8 1.4 -1.0 1.6 1.6 1.1 1.8 -0.5 -2.2 1.4 1.1 1.6 1.3 -1.6 -1.9 0.9 -1.7 1.5 -1.3 -2.2 -0.2 0.4 -1.5 1.6 -1.0
Risk taking 0.8 1.1 6.3 -0.3 0.8 -0.2 -0.1 0.0 0.0 -1.6 0.1 -0.2 1.6 0.8 -0.4 0.2 -0.3 1.7 -1.0 -0.3 -2.5 -1.8 -0.6 -0.7 -1.6 -1.1 -1.2
Ever had prostate specific antigen (PSA) test 0.7 0.8 3.3 -0.7 -1.8 -0.5 -0.5 -0.5 -0.4 -1.4 0.1 -0.7 1.0 0.5 -0.5 0.5 -0.1 1.2 -0.6 -0.7 -0.4 -0.8 -1.6 -1.0 -1.2 -0.3 -1.6
Fractured/broken bones in last 5 years 1.4 1.9 5.9 -2.0 -0.5 -2.0 -1.8 -1.4 -2.4 -0.3 1.5 -2.0 0.5 -0.7 -2.0 1.8 1.7 0.1 0.6 -1.9 0.3 0.4 -1.0 -0.3 0.0 -1.6 -0.8
Age started oral contraceptive pill 2.2 2.7 9.4 1.0 0.6 -0.0 -0.0 -0.7 -0.4 3.1 1.0 0.0 -2.2 -2.0 -0.0 0.3 1.1 -3.0 2.2 0.5 1.3 2.2 2.1 1.6 2.8 0.0 2.8
Diastolic blood pressure, automated reading 0.3 1.1 3.0 1.0 -0.6 0.9 0.5 0.6 1.1 1.4 -0.5 0.7 -1.2 -1.3 1.3 -0.6 -0.1 -1.4 1.3 0.6 1.5 1.0 0.8 -0.2 1.1 1.7 1.1
Ever depressed for a whole week 0.4 0.5 2.2 -0.7 -0.3 -0.7 -0.8 -0.7 -1.5 0.5 0.7 -0.6 -0.8 -0.2 -0.6 0.7 0.5 -0.8 0.4 -0.9 1.0 0.8 -0.6 -0.3 0.4 0.3 -0.6
Unable to work because of sickness or disability 0.5 0.7 1.5 0.7 0.3 0.9 0.8 -0.4 1.0 0.1 -1.2 0.8 0.1 1.1 1.2 -0.9 -1.2 0.3 -1.1 0.8 -0.7 -1.0 -0.3 0.4 -0.9 1.2 -0.9
Commuting to job workplace: Cycle 0.3 0.3 2.0 -0.1 1.4 -0.4 -0.4 0.2 -0.2 0.2 0.8 -0.5 0.5 -0.0 -0.1 0.6 0.6 0.4 -0.2 -0.2 0.4 0.5 0.6 0.0 0.6 -0.1 1.3
Myopia 1.1 1.7 6.7 1.5 2.6 1.6 1.3 1.2 2.0 -0.3 -1.0 1.3 0.1 0.2 1.8 -1.3 -1.5 0.2 -0.3 1.5 -1.3 -1.5 0.0 -0.6 -1.2 1.6 -0.8
Vascular/heart problems diagnosed by doctor 0.1 0.2 1.4 -0.1 0.7 0.1 0.1 0.1 0.3 0.4 0.2 0.1 -0.7 0.0 0.3 0.2 0.1 -0.1 0.0 0.3 -0.3 -0.3 1.2 0.3 0.1 -0.4 0.7
Cholesterol lowering medication 0.3 0.5 2.2 -0.0 -0.9 0.3 0.2 0.7 -0.1 0.5 -0.7 0.3 -1.4 -0.4 0.1 -0.5 0.1 -1.0 0.6 -0.1 1.5 1.0 0.6 0.5 0.7 0.7 0.4
Medication: Omeprazole (e.g. Zanprol) 2.4 2.9 6.1 -1.9 0.9 -2.2 -2.1 -2.5 -2.4 -0.1 2.0 -2.1 -0.3 -1.4 -2.5 2.2 2.1 -0.3 1.4 -2.2 0.3 1.3 -1.5 -1.4 1.1 -2.2 -0.1
Pain experienced in last month 0.4 0.6 3.1 -0.3 -0.3 0.2 0.1 0.3 0.7 -1.8 -0.2 -0.1 0.6 0.8 0.5 -0.1 -0.4 1.6 -1.0 0.0 -1.1 -0.8 -0.5 -1.2 -1.1 -0.1 -0.6
Supplements: Calcium 0.3 0.3 1.5 0.0 1.2 0.0 0.1 -0.6 -0.0 0.7 0.3 -0.1 -0.7 -0.6 0.0 0.0 0.4 -0.7 0.7 0.2 0.1 0.6 0.8 0.5 0.8 -0.2 1.1
Basal cell carcinoma (self-reported) 0.6 0.7 2.3 -0.5 1.1 -0.0 -0.2 -1.2 -0.0 -0.3 0.0 -0.3 1.4 1.3 0.3 0.1 -0.3 1.0 -1.3 -0.2 -1.1 -0.3 -1.5 -1.3 -0.6 0.3 -0.8
Heart attack/myocardial infarction (self-reported) 0.6 0.7 6.7 -0.2 2.6 -0.2 -0.1 0.2 -0.9 -1.1 0.4 -0.3 0.3 1.2 -0.5 0.1 -0.4 0.8 -1.1 -0.2 -0.5 -0.9 -0.6 0.3 -1.2 -0.5 -1.3
Deep venous thrombosis (DVT) (self-reported) 0.1 0.2 1.1 -0.0 -0.1 -0.3 -0.3 -0.1 -0.1 0.9 -0.0 -0.2 0.2 1.0 0.2 0.3 0.2 0.3 -1.1 -0.1 -0.0 -0.1 0.4 0.6 0.0 0.2 0.2
Heart disease (siblings) 0.5 0.6 1.5 0.8 -1.2 0.9 0.9 0.4 0.5 0.0 -1.1 0.8 -0.4 0.2 1.0 -1.1 -0.8 -0.3 -0.1 1.1 1.0 0.3 0.6 0.8 -0.1 1.2 0.7
Alcohol drinker status: Previous 0.8 0.9 2.0 1.3 -1.2 1.3 1.3 1.2 1.0 0.1 -1.4 1.0 -0.7 -0.7 1.1 -1.4 -0.7 -0.6 0.6 1.1 0.0 -0.4 1.3 0.7 0.2 1.0 0.8
Pack years of smoking 1.2 1.8 6.1 -1.5 -0.4 -0.8 -0.7 -1.9 -0.7 -2.5 -0.4 -0.6 1.8 0.6 -1.0 0.4 0.1 1.8 -0.7 -1.1 -0.9 -1.4 -1.9 -1.7 -1.8 -1.4 -2.0
Impedance of whole body 0.2 1.2 8.5 -0.6 2.9 -0.5 -0.6 -0.1 -0.7 0.7 1.7 -0.6 -1.4 -1.6 -0.5 0.9 0.8 -1.3 1.6 -0.6 0.4 0.5 0.2 -1.0 0.6 -1.2 -0.2
Leg fat mass (left) 0.1 0.5 3.6 0.4 -0.5 -0.1 0.2 -1.0 -0.3 1.0 -0.5 0.2 0.3 0.4 0.0 -0.4 -0.1 -0.6 -0.2 0.2 1.8 0.4 -0.1 1.9 0.4 0.9 0.2
Arm predicted mass (left) 0.1 0.3 1.6 0.2 -1.0 -0.5 -0.3 -0.7 -0.2 0.2 0.1 -0.2 0.1 -0.4 -0.3 0.1 0.5 0.1 0.2 -0.4 1.2 0.4 0.1 0.9 0.6 0.1 1.0