TWAS hub - SLC26A9

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1340	0.0310	6.0e-12	0.164	0.108	0.157	0.156	0.162	1.6e-19	4.4e-13	1.0e-18	1.7e-18	3.1e-19
2	TCGA	Kidney Renal Clear Cell Carcinoma	0.0658	0.0272	7.7e-06	0.067	0.042	0.057	NA	0.059	5.5e-08	1.5e-05	5.0e-07	NA	3.3e-07
3	TCGA	Kidney Renal Papillary Cell Carcinoma	0.1350	0.0580	3.4e-04	0.002	0.069	0.067	NA	0.040	2.5e-01	9.1e-05	1.1e-04	NA	2.4e-03
4	TCGA	Brain Lower Grade Glioma	0.0310	0.0179	7.4e-03	0.023	0.009	0.006	NA	0.013	9.9e-04	3.3e-02	6.0e-02	NA	1.1e-02
5	TCGA	Pancreatic Adenocarcinoma	0.1540	0.0770	2.4e-03	0.058	0.044	0.043	NA	0.046	1.9e-03	6.0e-03	6.7e-03	NA	5.1e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5
Peak expiratory flow (PEF)	14.5	33.6	97.6	-7.8	-1.5	2.3	-1.6	9.9
Hand grip strength (right)	5.0	13.5	59.1	-7.7	-0.1	0.6	-0.3	2.8
Prostate Cancer	4.9	6.9	20.8	-4.6	1.0	2.2	0.5	2.8
Exposure to tobacco smoke at home	4.4	5.0	16.2	0.3	-1.4	-2.6	-4.0	-0.3
Mean time to correctly identify matches	4.3	8.1	36.1	6.0	-1.2	0.0	-0.9	-1.5
Hand grip strength (left)	4.0	10.4	46.9	-6.8	0.4	0.2	0.5	2.2
Mother’s age at death	3.8	4.8	9.9	-2.9	3.1	0.7	-0.5	2.2
Comparative body size at age 10	3.7	10.3	36.7	-6.1	1.5	1.0	1.3	3.1
Medication: Cholesterol lowering	3.5	5.5	10.8	1.1	-3.3	-2.0	1.2	-3.1
Long-standing illness, disability or infirmity	3.5	5.4	11.8	1.2	-3.4	-2.9	-0.2	-2.3
Pulse wave reflection index	3.4	4.2	11.4	3.4	-1.6	-2.0	-1.0	-1.3
Multivitamins +/- minerals	3.2	4.0	14.7	3.8	0.4	-0.2	-2.3	0.3
Hearing difficulty/problems with background noise	3.2	5.1	17.8	-4.2	0.6	0.1	2.6	-0.9
Reaction Time	3.1	5.9	25.7	5.1	-1.0	-0.2	-1.2	-1.3
Severe depression (siblings)	3.1	3.4	8.5	2.9	0.2	-0.3	-2.9	0.0
Supplements: Glucosamine	3.1	4.0	8.5	2.9	2.5	2.0	-0.8	-0.9
Sitting height	3.1	21.7	83.5	-9.1	2.5	0.1	2.0	3.8
Number of self-reported non-cancer illnesses	3.0	5.2	11.9	2.1	-3.5	-2.2	-1.7	-1.4
Body Mass Index (BMI) (2010)	2.9	4.0	11.5	-3.4	0.0	1.2	1.9	1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	2.9	3.7	16.4	4.0	-0.6	-0.0	-1.1	-0.9
Lung FEV1/FVC ratio	2.7	13.6	33.2	-5.4	-0.3	2.1	1.2	5.8
Birth weight	2.7	5.8	16.4	-4.0	1.6	0.6	3.0	0.7
Arm predicted mass (right)	2.7	13.6	57.3	-7.6	1.2	-1.2	-0.7	2.8
Medication for cholesterol	2.7	4.1	10.9	-1.3	1.7	2.1	3.3	0.4
Illnesses of father: None of the above (group 1)	2.7	3.4	16.3	-4.0	-0.1	-0.3	0.7	0.3
Type 2 Diabetes (T2D) (2012)	2.6	3.1	7.7	-2.5	-0.4	-0.3	-1.0	2.8
Arm fat-free mass (right)	2.6	13.6	57.6	-7.6	1.3	-1.0	-0.5	2.7
Comparative height size at age 10	2.6	14.0	49.7	-7.0	3.4	-0.3	1.4	2.6
Mood swings	2.6	4.7	17.9	4.2	-0.3	2.1	-0.9	0.4
Mineral and other dietary supplements	2.6	3.5	11.0	-3.3	-2.4	-0.5	0.0	0.5
Whole body water mass	2.6	14.9	59.6	-7.7	1.6	-1.0	-0.6	3.3
Average weekly beer plus cider intake	2.6	3.7	6.8	2.5	-2.6	-0.6	-1.0	-2.1
Number of incorrect matches in round	2.5	4.1	16.8	4.1	-0.2	0.6	-0.7	-1.6
Trunk fat-free mass	2.5	14.2	54.9	-7.4	1.9	-1.2	-0.6	3.3
Trunk predicted mass	2.5	14.4	56.0	-7.5	1.8	-1.2	-0.6	3.3
Whole body fat-free mass	2.5	14.5	58.8	-7.7	1.7	-1.0	-0.4	3.1
Leg fat-free mass (right)	2.5	13.1	55.1	-7.4	1.5	-0.8	-0.2	2.8
Leg predicted mass (left)	2.4	12.6	52.1	-7.2	1.4	-0.7	-0.4	2.9
Handedness (chirality/laterality): Left-handed	2.4	2.9	5.7	1.5	2.1	2.4	1.3	0.4
Diabetes diagnosed by doctor	2.4	4.0	9.2	-1.9	-3.0	-1.9	1.8	-0.0
Leg predicted mass (right)	2.4	12.9	54.2	-7.4	1.5	-0.7	-0.3	2.8
Basal metabolic rate	2.4	13.2	54.5	-7.4	1.4	-0.9	-0.6	2.9
Leg fat-free mass (left)	2.3	12.4	51.8	-7.2	1.4	-0.6	-0.4	2.8
Average weekly fortified wine intake	2.3	2.7	6.0	2.2	1.4	2.4	-1.1	0.2
Age when periods started (menarche)	2.3	5.6	16.3	4.0	-1.7	-1.6	0.2	-2.5
Tense / ‘highly strung’	2.3	3.8	16.2	4.0	-0.3	0.7	-0.8	-1.2
Medication for cholesterol, blood pressure or diabetes	2.3	3.8	12.2	-0.8	3.5	1.3	-0.7	1.9
Illnesses of father: High blood pressure	2.3	2.8	6.1	2.5	-0.4	-1.2	-1.7	-1.9
Arm fat-free mass (left)	2.3	11.6	47.5	-6.9	1.3	-1.0	-0.5	2.7
Arm predicted mass (left)	2.3	11.9	48.9	-7.0	1.2	-0.9	-0.8	2.8
Seen doctor (GP) for nerves, anxiety, tension or depression	2.2	3.4	12.4	3.5	-1.5	0.1	-1.1	-1.1
Number of treatments/medications taken	2.1	3.7	10.0	3.2	-1.7	-1.3	-1.8	-0.8
Medication: Allopurinol	2.1	2.7	8.8	-1.0	-1.8	-3.0	-0.2	-0.9
Medication: Gliclazide	2.1	2.3	7.5	-0.1	-2.7	-1.8	0.4	-0.9
Supplements: Fish oil (including cod liver oil)	2.1	2.7	6.1	2.5	2.5	0.6	-1.0	0.6
Commuting to job workplace: Cycle	2.1	2.5	6.3	0.6	1.5	2.5	0.1	1.9
Type 2 Diabetes (T2D) (2018)	2.0	3.8	6.7	-2.5	-2.6	-1.9	1.6	0.0
Medication: Metformin	1.9	2.7	5.5	-1.9	-2.1	-2.3	0.3	-0.1
Mouth/teeth dental problems	1.9	2.9	4.5	-2.1	2.0	1.5	2.0	0.4
Illnesses of mother	1.9	2.4	6.1	-1.4	-1.6	-2.5	-0.8	-0.9
Rheumatoid Arthritis	1.8	2.5	5.2	0.9	-2.1	0.2	-1.4	2.3
Diabetes (self-reported)	1.8	2.8	7.2	-1.6	-2.7	-1.8	0.9	0.6
Eye problems/disorders: None of the above	1.8	2.0	3.9	-1.9	-1.0	-0.8	-2.0	1.0
Pulse rate, automated reading	1.8	5.8	24.0	-4.9	-1.3	-0.7	0.6	1.6
Financial situation satisfaction	1.8	2.3	5.8	-1.8	-1.3	0.9	-0.3	2.4
HDL Cholesterol	1.7	2.9	6.8	2.6	1.1	-1.2	-2.3	0.2
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	6.0	2.5	-0.9	-1.5	-0.4	-1.4
Vitamin and mineral supplements	1.7	2.2	10.2	-3.2	-0.7	-0.2	0.5	-0.5
Mouth/teeth dental problems: Bleeding gums	1.7	2.2	5.1	0.6	-1.0	-2.2	-2.1	0.2
Medication for pain relief, constipation, heartburn	1.7	2.8	6.7	-2.6	2.1	1.2	0.8	1.0
Medication: Blood pressure	1.7	3.0	11.3	1.0	-3.4	-1.5	-0.2	-0.5
HbA1C	1.6	1.8	6.3	-2.5	-0.8	-0.7	0.2	1.2
Weight	1.6	7.8	32.5	-5.7	0.7	-0.7	-0.9	2.2
Time employed in main current job	1.6	1.9	5.7	0.4	2.4	-0.3	-1.1	1.4
Number of live births	1.6	2.3	3.3	1.8	-1.7	-0.5	-1.6	-1.6
Gout (self-reported)	1.6	2.2	4.7	-1.6	-1.2	-2.2	0.8	-1.3
Exposure to tobacco smoke outside home	1.6	2.1	6.3	0.6	-2.5	-1.5	-0.2	-1.2
Pulse wave peak to peak time	1.6	1.9	3.9	-2.0	1.7	1.0	1.4	0.0
Medication: Blood pressure	1.6	3.1	7.1	2.0	-1.7	0.3	-2.7	1.1
High cholesterol (Self-reported)	1.6	2.9	5.2	1.5	-2.1	-2.3	-1.4	-0.6
Medication: Atorvastatin	1.6	1.9	8.4	-0.3	-2.9	-0.8	-0.8	-0.3
Impedance of leg (right)	1.5	7.0	25.6	5.1	-1.9	0.2	0.1	-2.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	5.6	-0.2	-0.0	2.4	-1.8	1.2
Impedance of leg (left)	1.5	7.4	24.2	4.9	-2.1	0.0	0.4	-2.8
Pain all over the body in last month	1.5	1.6	5.6	-0.6	2.4	0.9	1.1	-0.6
Medication: Ramipril	1.5	2.0	4.4	1.0	-2.1	-0.8	-2.0	0.1
Neuroticism score	1.5	3.1	9.9	3.1	-1.1	1.5	-1.3	-0.8
Pulse rate	1.5	2.5	4.5	-2.1	-0.8	-0.8	-1.9	1.8
Serious illness, injury or assault of a close relative in last 2 years	1.5	1.8	4.9	1.2	-0.8	-2.2	-0.4	-1.2
Pulse wave Arterial Stiffness index	1.5	1.7	3.2	1.5	-1.8	-1.2	-1.3	0.1
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	3.1	-1.0	1.7	1.2	1.8	0.6
Osteoarthritis (self-reported)	1.5	1.9	6.9	2.6	0.3	1.0	0.1	-1.3
Guilty feelings	1.5	2.2	7.0	1.5	-0.5	2.6	0.5	-1.1
Depressed Affect (Nagel 2018)	1.4	2.9	8.5	2.3	-0.4	2.9	-0.6	0.5
Ulcerative Colitis (UC)	1.4	2.7	9.1	3.0	-0.8	-1.1	-0.7	-1.4
Neuroticism	1.4	3.4	9.1	3.0	-1.3	2.5	-0.2	-0.4
Medication: Simvastatin	1.4	2.0	4.1	1.2	-1.0	-2.0	-0.4	-1.8
Falls in the last year	1.4	1.9	5.8	-2.4	1.3	0.2	-0.9	1.0
Hair/balding pattern: Pattern 3	1.4	2.0	6.7	2.6	0.5	0.4	-1.3	-1.2
Forced expiratory volume in 1-second (FEV1)	1.4	4.7	12.1	-3.5	-1.4	-0.0	-1.1	2.9
Standing height	1.4	13.4	52.4	-7.2	1.9	-0.5	0.5	3.2
Breastfed as a baby	1.4	1.8	7.3	2.7	0.4	-1.1	-0.3	-0.2
Family relationship satisfaction	1.4	1.7	3.4	0.9	0.2	1.8	0.9	1.9
Friendships satisfaction	1.4	1.7	4.3	0.6	-0.1	1.8	0.7	2.1
Eye problems/disorders: Cataract	1.4	1.6	3.2	1.5	0.6	1.5	1.8	0.2
Impedance of whole body	1.4	7.2	24.1	4.9	-1.4	0.9	1.4	-2.6
Depression (Nagel 2018)	1.3	2.0	9.2	-0.1	0.1	3.0	-0.3	0.9
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	2.7	0.0	-1.2	-1.2	1.6	-1.2
Medication: Co-codamol	1.3	1.6	2.6	1.4	1.0	-1.3	-1.6	-0.7
Townsend deprivation index at recruitment	1.3	1.8	3.3	1.7	-1.8	-0.9	-1.4	-0.3
Heart attack	1.3	1.6	5.1	0.8	-2.3	-0.7	-1.0	-1.0
Hayfever/allergic rhinitis (self-reported)	1.3	1.8	2.9	-0.9	-1.5	-1.6	-0.1	1.7
Impedance of arm (right)	1.3	6.3	24.5	5.0	-0.4	1.1	1.1	-2.0
Depression (self-reported)	1.3	1.5	4.0	2.0	0.6	0.4	0.3	-1.8
Lung cancer (father)	1.3	1.5	4.5	-0.2	1.7	2.1	0.4	0.3
Risk taking	1.3	1.9	5.1	2.3	-1.5	-0.3	0.1	-1.5
Vascular/heart problems diagnosed by doctor	1.3	3.5	8.8	-2.1	3.0	0.2	2.0	0.4
Hearing difficulty/problems: Yes	1.2	1.8	6.5	-2.5	-1.3	-0.8	-0.1	0.4
Qualifications: CSEs or equivalent	1.2	1.6	4.9	0.6	-1.3	0.2	-1.1	2.2
Medication: Atenolol	1.2	1.6	3.5	1.4	-0.5	1.9	-1.4	0.4
Hair/balding pattern: Pattern 2	1.2	1.6	3.8	-1.6	0.5	-1.9	0.6	-0.8
Worrier / anxious feelings	1.2	2.3	6.6	2.6	-0.4	1.1	-1.4	-1.3
Number of full brothers	1.2	1.5	4.9	-0.3	-0.7	1.4	-0.3	2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.4	4.7	1.2	-0.0	-1.0	-2.2	-0.1
Illnesses of father: Heart disease	1.2	1.7	6.6	2.6	-1.3	0.4	0.2	0.1
Ever had bowel cancer screening	1.2	1.4	4.1	0.7	-2.0	-0.5	-0.1	-1.4
Ever had prostate specific antigen (PSA) test	1.2	1.4	6.6	-2.6	0.4	-0.3	0.3	-0.2
Heart attack/myocardial infarction (self-reported)	1.2	1.5	5.4	0.6	-2.3	-0.6	-0.8	-1.0
Alzheimer’s Disease (in father)	1.1	1.2	4.1	2.0	-0.3	1.3	0.6	0.1
Crohns Disease (2012)	1.1	1.7	4.2	1.9	-0.4	-0.3	0.7	-2.0
Ulcerative Colitis	1.1	1.6	3.7	1.9	-1.1	-1.3	-0.7	-1.1
Cardiovascular Disease	1.1	3.6	8.1	2.8	-2.5	-1.0	-1.5	-0.7
Taking other prescription medications	1.1	1.7	3.7	1.6	-1.9	-0.8	-1.3	-0.2
Medication: Levothyroxine sodium	1.1	1.8	4.0	2.0	-1.0	-1.2	-0.4	-1.6
High blood pressure (mother)	1.1	1.5	3.2	1.7	1.1	1.8	-0.4	0.5
Medication: Lansoprazole	1.1	1.2	3.3	0.1	-1.2	-0.7	-0.9	-1.8
Impedance of arm (left)	1.1	5.1	18.0	4.2	-0.5	1.3	1.5	-1.8
Birth weight of first child	1.1	2.0	7.0	-2.6	0.3	-1.5	0.1	0.9
Loud music exposure frequency	1.1	1.2	2.1	-1.1	1.4	-0.6	1.5	-0.5
High blood pressure (siblings)	1.1	1.6	4.2	1.2	0.3	2.0	-1.2	1.0
Medication: Omeprazole	1.1	1.4	3.7	-0.1	-0.2	-1.9	-1.7	0.5
Medication: Aspirin	1.1	1.4	3.6	1.7	-1.9	0.1	-0.7	0.3
Pain type(s) experienced in last month: Hip pain	1.1	1.4	3.7	0.4	-0.8	1.9	-1.5	0.5
Cholesterol lowering medication	1.1	1.7	5.6	0.6	-0.5	-1.3	-2.4	0.8
Bipolar Disorder (2018)	1.0	1.5	5.5	2.3	-0.0	1.4	0.1	0.3
Neuroticism (Nagel 2018)	1.0	2.3	5.2	2.3	-0.7	2.0	-1.2	0.6
Irritable Bowel Disease (IBD)	1.0	2.3	8.1	2.9	-0.7	-0.3	0.0	-1.7
Angina	1.0	1.4	2.8	0.7	-1.5	-0.7	0.8	-1.7
Stomach or abdominal pain in last month	1.0	1.3	4.1	1.4	-2.0	0.3	-0.1	-0.4
Diverticular disease/diverticulitis (self-reported)	1.0	1.2	2.3	1.5	-0.7	-1.0	-1.5	0.4
Prospective memory result	1.0	1.3	2.5	1.4	0.5	0.6	1.1	-1.6
Length of working week for main job	1.0	1.1	2.5	-1.0	0.1	-1.4	-0.1	1.6
Medication: Amlodipine	1.0	1.5	3.9	0.8	-2.0	-1.5	-0.5	-0.7
Neck or shoulder pain in last month	1.0	1.5	3.5	-1.4	-0.7	0.9	1.9	-0.6
Back pain experienced in last month	1.0	1.5	3.9	-2.0	-1.0	0.2	-0.5	1.5
Medication: Paracetamol	1.0	1.5	4.5	2.1	-0.8	-0.4	-1.2	-0.8
Supplements: Calcium	1.0	1.1	2.8	1.7	1.2	0.3	0.8	-0.7
Worry (Nagel 2018)	0.9	2.0	7.3	2.7	-0.0	1.0	-1.1	-0.8
Coronary Artery Disease (CAD)	0.9	1.1	4.9	-2.2	-0.5	0.2	0.5	0.0
BMI	0.9	5.4	25.5	-5.0	0.3	-0.5	0.7	0.9
Supplements: Zinc	0.9	0.9	3.6	-0.1	1.9	0.0	1.0	-0.0
Diabetes (mother)	0.9	1.1	2.1	-0.4	1.4	1.3	0.9	1.0
Pack years adult smoking proportion	0.9	1.3	2.6	-0.4	-1.6	-0.7	-1.1	-1.5
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	1.7	-0.6	-0.0	1.3	-1.2	1.3
High blood pressure	0.9	2.5	5.0	2.1	-2.2	0.2	-1.7	0.2
Chronic bronchitis/emphysema (father)	0.9	1.1	2.1	-0.8	-1.0	-0.3	-1.3	1.4
Nervous feelings	0.9	1.8	7.8	2.8	-0.2	0.8	-0.2	-0.7
Had menopause	0.9	1.1	4.7	0.5	0.3	2.2	0.0	0.7
Worry too long after embarrassment	0.9	1.4	3.0	0.2	-1.7	-0.6	-1.7	1.0
Overall health rating	0.9	1.9	5.9	0.9	-2.4	-1.1	-0.7	-1.0
Medication: Aspirin	0.9	1.2	2.7	1.6	-1.5	-0.4	-1.0	0.0
Supplements: Vitamin C	0.9	1.1	2.6	0.7	-0.2	1.6	1.3	0.9
Hypertension (Self-reported)	0.9	2.5	7.5	1.9	-2.7	-0.0	-1.2	0.2
Loneliness, isolation	0.9	1.2	2.4	1.3	-0.2	1.4	-1.6	0.2
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	4.0	1.2	-0.6	-2.0	-1.1	-0.6
Miserableness	0.9	1.6	5.6	1.0	1.0	2.4	-0.4	0.4
Pack years of smoking	0.9	1.3	2.8	-0.4	-1.7	-0.7	-1.0	-1.4
Schizophrenia vs Biploar Disorder	0.8	1.1	2.3	-1.4	0.4	0.3	-0.9	1.5
Alzheimer’s Disease (in mother)	0.8	0.9	1.4	1.2	1.1	-0.9	-0.4	-0.9
Ovarian Cancer	0.8	1.0	4.1	-0.3	0.5	0.4	-2.0	0.7
Fasting Glucose	0.8	1.0	3.9	-0.9	0.2	0.1	0.7	-2.0
Neuroticism (2016)	0.8	1.1	4.2	1.0	0.2	2.0	-0.5	0.4
Primary Biliary Cirrhosis	0.8	1.2	3.5	-1.9	-1.1	0.9	0.5	0.2
Height	0.8	15.5	68.7	-8.3	1.2	-0.2	1.1	2.5
Frequency of depressed mood in last 2 weeks	0.8	1.1	3.4	1.0	0.2	1.8	-1.1	-0.3
Ever unenthusiastic/disinterested for a whole week	0.8	1.0	2.9	0.6	-1.7	-0.3	-1.3	0.0
Hip circumference	0.8	3.6	13.0	-3.6	0.0	-1.0	-1.1	1.7
Father’s age at death	0.8	1.1	3.8	-0.1	1.9	1.0	-0.5	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.5	5.7	-2.4	-1.6	-1.4	-0.7	1.3
Blood clot in the leg (DVT)	0.8	1.0	2.0	-0.7	1.4	0.7	0.2	1.4
Angina (self-reported)	0.8	1.1	2.4	0.8	-1.3	-0.6	0.6	-1.5
Heart disease (mother)	0.8	0.9	2.4	0.5	-0.0	1.6	1.2	0.7
Number of full sisters	0.8	0.9	1.2	-0.4	-1.0	1.1	1.0	1.1
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.7	-0.8	-0.1	-0.9	0.7	-1.6
Qualifications: nursing, teaching	0.8	1.3	5.1	0.2	2.2	0.6	1.1	-0.0
Medication: Bendroflumethiazide	0.8	1.3	3.5	1.9	-1.4	0.1	-0.1	-0.9
Pain experienced in last month	0.8	1.3	3.0	0.1	1.5	-0.2	-1.7	1.0
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.2	-0.8	1.5	0.6	0.4	1.4
Crohns Disease (2017)	0.7	1.5	3.8	2.0	-0.2	0.1	0.5	-1.8
Lupus	0.7	1.1	2.5	1.4	0.3	-0.7	-1.6	-0.7
Waist circumference	0.7	2.5	8.9	-3.0	-0.1	-0.6	-1.5	1.0
Arm fat mass (right)	0.7	2.7	11.7	-3.4	-0.0	-0.2	-0.6	1.2
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	4.0	-2.0	0.8	-0.1	0.3	0.9
Medication: Paracetamol	0.7	1.2	2.2	1.4	-1.3	-0.4	-1.5	-0.3
Headache pain in last month	0.7	1.2	3.5	1.9	-0.3	-1.0	-0.7	-0.8
Shortness of breath walking on level ground	0.7	0.9	2.8	0.2	-0.9	-0.8	0.3	-1.7
Emphysema/chronic bronchitis	0.7	0.8	2.4	-0.4	-1.6	-0.7	1.1	-0.2
Migraine (self-reported)	0.7	0.9	1.9	-0.6	-1.4	-0.4	-0.9	1.1
Osteoporosis (self-reported)	0.7	0.9	3.8	0.2	0.3	-0.5	2.0	-0.4
Arm fat mass (left)	0.7	3.1	13.6	-3.7	-0.3	-0.2	-0.5	1.2
Tinnitus: Yes, now most or all of the time	0.7	0.8	3.1	-1.8	-0.6	0.2	-0.5	0.5
Medication: Lisinopril	0.7	0.9	2.8	-0.5	-0.1	-1.7	-0.8	1.0
Unable to work because of sickness or disability	0.7	0.9	2.2	0.1	-0.4	1.4	1.5	0.5
Intelligence (Savage-Jansen 2018)	0.6	2.0	5.3	-2.3	-1.0	-1.0	0.3	1.6
Alzheimer’s Disease (including proxy)	0.6	0.9	2.9	1.7	1.0	-0.3	-0.6	-0.3
Blood Eosinophil Count	0.6	4.6	8.4	-2.1	0.9	2.9	1.4	2.7
Allergy or Eczema	0.6	1.6	5.3	-1.4	0.7	0.4	0.5	2.3
Medication for hormone replacement therapy	0.6	0.7	1.4	0.6	0.2	-1.2	-1.0	-0.9
Maternal smoking around birth	0.6	0.8	2.0	1.4	0.1	0.5	-0.2	-1.3
Hayfever, allergic rhinitis or eczema	0.6	1.3	5.1	-1.0	0.4	-0.5	0.2	2.3
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	2.0	1.4	0.1	1.4	0.2	-0.9
Happiness	0.6	0.8	2.9	0.9	0.2	1.7	-0.3	0.1
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.1	0.9	0.3	0.7	-0.9	1.1
Wheeze or whistling in the chest in last year	0.6	1.1	3.1	-0.6	-1.8	0.2	-1.0	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.8	0.4	-0.7	1.0	0.2	-1.4
Health satisfaction	0.6	0.8	2.5	0.2	-1.6	0.8	-0.5	0.6
Qualifications: College or University degree	0.6	1.7	3.3	-1.8	1.6	0.3	1.6	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.7	0.4	-0.3	-0.8	0.8	-1.3
Whole body fat mass	0.6	2.5	11.7	-3.4	-0.4	-0.3	-0.4	0.7
Age at last live birth	0.6	0.9	1.8	-1.1	0.1	-1.4	-1.1	0.4
Knee pain experienced in last month	0.6	0.9	2.6	1.2	-0.7	1.6	0.4	-0.1
Smoking status: Previous	0.6	0.9	1.7	1.1	0.3	-1.3	-0.1	1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	2.2	0.6	1.5	0.6	-0.6	0.4
Commuting to job workplace: Walk	0.6	0.7	1.6	-0.1	-0.1	1.0	-1.3	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	3.0	0.4	0.6	-1.7	-0.3	-0.4
Breast cancer (self-reported)	0.6	0.7	1.3	-0.9	-0.8	-0.7	-1.1	0.4
Ever smoked	0.6	1.0	1.9	1.2	0.8	-1.4	-1.1	0.3
Age started oral contraceptive pill	0.6	0.8	1.8	1.4	-0.1	0.9	0.6	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.4	-1.1	0.3	-1.2	-0.8	0.6
Heart disease (siblings)	0.6	0.7	1.2	0.4	-0.7	1.1	-1.1	0.7
Leg fat mass (left)	0.6	2.3	10.0	-3.2	-0.6	-0.3	-0.8	0.7
Bipolar Disorder or Schizophrenia	0.5	1.3	6.2	2.5	0.0	-0.1	-0.4	-0.5
Major Depression (MDD)	0.5	0.6	1.3	1.2	-0.4	-1.1	0.6	0.0
Verbal and Numeric Reasoning (VNR)	0.5	1.1	4.7	-2.2	0.3	-0.2	0.5	0.7
Breast Cancer	0.5	1.1	2.4	1.1	1.6	-0.7	-1.0	-0.7
Respiratory disease	0.5	1.2	2.1	-1.0	-1.5	-1.1	-0.3	1.3
Lung FVC	0.5	2.6	6.7	2.6	-1.9	-1.1	-1.1	-0.8
Sensitivity / hurt feelings	0.5	0.9	1.6	1.1	-1.3	0.6	-1.2	0.4
Relative age of first facial hair	0.5	1.1	2.8	1.1	-0.1	-0.9	-1.7	0.8
Current tobacco smoking	0.5	0.8	3.1	0.6	0.6	1.8	-0.2	0.1
Fed-up feelings	0.5	0.9	3.5	1.0	-0.2	1.9	0.2	0.0
Serious illness, injury or assault to yourself	0.5	0.6	1.2	1.0	-0.9	-0.1	0.0	-1.1
Body mass index (BMI)	0.5	1.9	7.3	-2.7	-0.2	-0.5	-1.1	0.9
Trunk fat mass	0.5	2.2	10.4	-3.2	-0.4	-0.3	-0.2	0.6
Past tobacco smoking	0.5	1.0	1.9	-1.0	0.1	1.4	0.8	-1.1
Alcohol usually taken with meals	0.5	0.9	3.1	1.8	-0.2	-0.6	-0.9	-0.0
Qualifications: None of the above	0.5	1.1	2.7	1.6	-0.7	-0.7	0.0	-1.3
Fluid intelligence score	0.5	1.1	3.9	-2.0	0.5	-0.3	-0.1	1.1
Illnesses of siblings	0.5	0.7	1.5	-0.3	0.5	-1.2	1.0	-0.8
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.6	-0.7	0.8	1.6	-0.4	-0.1
Qualifications: A levels/AS levels or equivalent	0.5	1.2	2.5	-1.6	1.0	-0.3	0.7	1.4
Ever highly irritable/argumentative for 2 days	0.5	0.6	2.3	0.0	-0.7	0.4	-0.0	-1.5
Medication: Ventolin 100micrograms inhaler	0.5	0.6	1.1	-0.5	0.8	1.1	0.2	1.0
Mouth/teeth dental problems: Loose teeth	0.5	0.7	2.1	0.4	0.5	1.5	-0.4	0.8
Leg fat mass (right)	0.5	2.0	8.9	-3.0	-0.5	-0.3	-0.8	0.5
Suffer from ‘nerves’	0.5	0.8	2.7	0.7	-0.3	1.6	-0.2	0.8
Illnesses of siblings: Diabetes	0.5	0.6	2.4	-1.5	-0.1	0.5	0.8	0.0
Average weekly red wine intake	0.5	0.8	1.9	1.4	-1.2	-0.0	-0.7	-0.2
Ever taken oral contraceptive pill	0.5	0.6	0.8	0.8	-0.7	-0.5	-0.8	0.9
Hearing aid user	0.5	0.5	1.5	-0.5	0.3	1.2	0.9	0.0
Eye problems/disorders: Glaucoma	0.5	0.6	1.8	0.8	1.4	0.3	-0.4	0.7
Ever depressed for a whole week	0.5	0.6	1.7	0.5	-0.7	0.1	-0.9	1.3
Myopia	0.5	0.7	2.1	-0.7	-0.7	-1.5	-0.5	0.3
Schizophrenia (2018)	0.4	0.9	1.8	1.3	0.1	-1.2	-0.6	-0.9
Mean Putamen Volume	0.4	0.5	1.7	0.5	0.2	-1.3	-0.3	0.5
Triglycerides	0.4	0.7	1.2	-0.6	-1.1	-0.8	0.5	-1.1
Ever used hormone-replacement therapy (HRT)	0.4	0.6	2.4	0.2	-0.1	1.6	0.3	0.5
Systolic blood pressure, automated reading	0.4	1.1	2.8	1.7	-1.2	-0.3	-0.3	-1.0
Forced vital capacity (FVC)	0.4	1.7	4.3	-2.1	-1.5	-0.3	-0.8	1.2
Allergy	0.4	1.0	3.0	1.2	0.0	0.5	-0.4	-1.7
Mouth/teeth dental problems: Dentures	0.4	0.6	1.4	0.9	-0.3	0.8	0.1	-1.2
Asthma	0.4	0.8	1.6	0.4	-1.0	-1.2	-0.9	0.3
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.2	0.6	-0.8	-0.1	1.1	0.4
Hair/balding pattern: Pattern 4	0.4	0.9	2.8	-1.2	-1.7	-0.3	0.3	0.3
Glaucoma (self-reported)	0.4	0.4	1.5	1.2	-0.1	0.2	-0.7	0.2
Forced vital capacity (FVC), Best measure	0.4	1.5	3.9	-1.2	-1.2	-2.0	-0.8	0.1
Medication: Ibuprofen	0.4	0.5	0.9	0.9	-0.3	0.6	0.9	0.8
Chest pain or discomfort	0.4	0.6	2.5	-0.2	-1.6	-0.3	-0.4	0.4
Leg pain on walking	0.4	0.5	1.3	0.4	-0.1	1.1	1.0	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.5	-0.3	-1.2	0.6	-0.6	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	2.3	-1.5	0.6	-0.5	-0.8	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	3.5	-0.8	-1.9	0.3	-0.2	0.4
Wears glasses or contact lenses	0.4	0.4	1.0	0.1	0.8	0.5	0.1	-1.0
Commuting to job workplace: Public transport	0.4	0.5	1.1	0.9	1.1	-0.2	0.7	-0.3
Irritability	0.4	0.7	2.1	0.5	-1.5	-0.2	-0.5	0.8
Basal cell carcinoma (self-reported)	0.4	0.5	2.0	1.4	0.1	0.2	-0.4	0.2
Schizophrenia (2014)	0.3	0.7	2.8	1.7	-0.1	-0.3	-0.2	-0.7
Blood White Count	0.3	2.3	9.1	0.7	0.4	3.0	0.8	1.0
Heel T-Score	0.3	2.1	7.6	-1.3	2.8	-1.0	-0.4	-0.6
Systolic Blood Pressure	0.3	1.6	3.5	1.8	-1.9	-0.1	-0.3	-1.1
Smoking Status	0.3	0.7	2.9	1.7	-0.7	0.5	0.1	0.0
Hair Pigment	0.3	7.1	25.7	5.1	1.1	0.7	-2.8	0.6
Average weekly spirits intake	0.3	0.4	0.9	-1.0	-0.9	-0.2	0.2	-0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	1.8	-0.6	-0.2	-0.7	-0.6	-1.4
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	0.6	-0.6	0.7	0.5	-0.5	0.8
Had other major operations	0.3	0.3	1.0	0.0	-1.0	0.5	-0.4	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	3.1	-1.8	-0.5	-0.4	0.0	0.2
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.4	1.1	-0.7	-0.2	-0.1	-1.2
Number of children fathered	0.3	0.4	1.2	1.1	-0.4	0.1	-0.3	-0.6
Had major operations	0.3	0.4	1.1	0.5	-1.0	-0.6	-0.0	0.5
Asthma (self-reported)	0.3	0.6	1.2	0.4	-0.7	-1.1	-0.9	0.3
Smoking status: Current	0.3	0.4	1.9	0.3	-0.1	1.4	-0.3	0.2
Average weekly champagne plus white wine intake	0.3	0.4	1.1	0.1	1.1	-0.7	-0.5	0.1
Alcohol drinker status: Never	0.3	0.4	0.8	0.5	-0.9	0.7	0.2	0.6
Number of operations (self-reported)	0.3	0.4	0.8	0.8	-0.9	0.6	0.3	-0.3
Diastolic blood pressure, automated reading	0.3	1.0	3.6	0.6	-0.9	0.1	-1.9	0.4
Blood Platelet Count	0.2	2.0	4.0	-1.8	0.7	1.3	-0.9	2.0
Chronotype (morning person)	0.2	0.5	1.5	-0.8	-0.5	1.2	0.4	-0.3
Noisy workplace	0.2	0.2	0.4	0.6	-0.3	-0.1	-0.6	-0.3
Leg fat percentage (right)	0.2	0.8	2.1	-0.1	-1.3	-0.0	-1.4	-0.2
Age at first live birth	0.2	0.4	1.2	-1.1	0.5	-0.8	0.2	0.3
Medication: Seretide 50 evohaler	0.2	0.3	0.8	0.1	-0.2	-0.1	0.7	-0.9
Leg fat percentage (left)	0.2	0.8	2.0	-0.3	-1.4	-0.1	-1.3	-0.4
Fractured/broken bones in last 5 years	0.2	0.3	0.9	0.1	-0.3	0.9	-0.3	0.4
Age at First Birth	0.1	0.1	0.4	0.2	0.7	-0.2	0.1	0.4
Waist Hip Ratio (WHR)	0.1	0.6	2.2	0.0	0.6	1.5	-0.3	0.6
Hypothyroidism (self reported)	0.1	0.3	0.6	0.7	0.1	0.6	0.2	-0.8
Tanning	0.1	1.2	2.8	0.5	1.2	1.7	0.6	1.0
Trunk fat percentage	0.1	0.4	1.2	-1.1	-0.9	0.0	0.1	-0.4
Relative age voice broke	0.1	0.2	0.4	0.5	0.4	0.3	-0.6	-0.1
Financial difficulties in last 2 years	0.1	0.2	0.4	-0.1	0.5	-0.4	-0.2	-0.6
Arm fat percentage (right)	0.1	0.3	1.1	-1.1	-0.5	-0.0	-0.5	0.2
Alcohol intake versus 10 years previously	0.1	0.2	0.5	-0.2	-0.4	-0.7	-0.3	0.5
Body fat percentage	0.1	0.5	1.0	-1.0	-1.0	-0.1	-0.5	-0.3
Alcohol intake frequency.	0.1	0.3	0.6	-0.6	-0.7	0.1	-0.2	0.8
Arm fat percentage (left)	0.1	0.5	2.0	-1.4	-0.6	-0.0	-0.4	0.3
Alcohol drinker status: Previous	0.1	0.1	0.3	0.3	-0.6	0.2	0.0	-0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
LDL Cholesterol	0.0	0.1	0.3	-0.3	0.5	-0.1	0.0	0.1
Blood Red Count	0.0	0.5	0.9	-0.4	-0.7	-1.0	-0.8	0.3
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	0.0	0.1	-0.2	0.1	-0.1
Diabetes (father)	0.0	0.1	0.1	0.3	-0.4	0.1	-0.1	-0.1

Hub : Genes

SLC26A9

Models

Trait associations