TWAS hub - SLC35B2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.255	0.0418	3.1e-09	0.197	0.107	0.183	0.188	0.187	8.0e-25	1.4e-13	6.7e-23	1.3e-23	1.7e-23
2	YFS	Blood	0.179	0.0248	0.0e+00	0.150	0.103	0.150	0.149	0.150	9.8e-47	7.9e-32	8.7e-47	2.7e-46	8.8e-47

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Commuting to job workplace: Walk	6.4	6.9	10.2	1.9	-3.2
Qualifications: CSEs or equivalent	6.0	7.9	8.9	3.0	-2.6
Medication: Simvastatin	5.7	8.3	16.3	-4.0	0.6
Medication: Aspirin	4.4	5.7	9.9	-3.1	1.3
Eye problems/disorders: Glaucoma	4.4	5.2	10.2	-3.2	0.5
Illnesses of mother	4.2	5.1	9.4	3.1	-0.9
Medication: Aspirin	3.9	5.1	9.5	-3.1	0.9
Neuroticism (Nagel 2018)	3.4	8.0	14.7	-3.8	1.2
Miserableness	3.4	5.9	10.8	-3.3	1.0
Ever had hysterectomy (womb removed)	3.1	3.5	5.6	1.2	-2.4
Glaucoma (self-reported)	3.1	3.6	6.8	-2.6	0.7
Medication: Ventolin 100micrograms inhaler	3.1	4.0	7.8	-0.3	2.8
Medication: Blood pressure	2.9	5.2	10.3	-3.2	0.1
Depression (Nagel 2018)	2.8	4.2	7.6	-2.8	0.8
Eye problems/disorders: None of the above	2.7	3.1	3.8	1.9	1.6
Heart disease (siblings)	2.7	3.3	4.0	-2.0	1.6
Depressed Affect (Nagel 2018)	2.6	5.4	9.9	-3.1	0.9
Fed-up feelings	2.6	4.7	9.3	-3.0	-0.5
Nervous feelings	2.6	4.9	6.6	-2.6	1.8
Medication: Ramipril	2.6	3.3	6.5	-2.6	-0.4
Illnesses of siblings	2.6	3.7	4.9	1.6	-2.2
Number of children fathered	2.6	2.9	3.9	-1.4	-2.0
Serious illness, injury or assault of a close relative in last 2 years	2.5	2.9	5.2	-0.7	-2.3
Alzheimer’s Disease (including proxy)	2.4	3.4	6.5	-2.5	0.6
Primary Biliary Cirrhosis	2.4	3.4	6.1	2.5	-0.9
Medication for cholesterol, blood pressure or diabetes	2.4	4.1	7.6	2.7	-0.7
Osteoporosis (self-reported)	2.4	2.9	5.7	-0.4	-2.4
Tinnitus: Yes, now most or all of the time	2.4	2.8	3.0	-1.7	1.6
Medication: Lisinopril	2.4	3.0	4.6	-1.2	2.2
Exposure to tobacco smoke at home	2.3	2.6	3.4	-1.4	1.8
Angina (self-reported)	2.3	3.0	3.4	-1.6	1.8
Chest pain or discomfort	2.3	3.3	6.5	-2.5	-0.4
Worry (Nagel 2018)	2.2	4.6	6.6	-2.6	1.6
Alzheimer’s Disease (in mother)	2.2	2.6	5.2	-2.3	0.2
Ovarian Cancer	2.2	2.9	4.6	1.1	-2.1
Crohns Disease (2012)	2.2	3.6	6.9	2.6	-0.5
Number of treatments/medications taken	2.2	4.0	7.7	-2.8	0.4
Length of working week for main job	2.2	2.4	2.9	1.4	-1.7
Shortness of breath walking on level ground	2.2	2.6	3.1	-1.5	1.8
Relative age of first facial hair	2.1	4.4	7.6	1.1	2.8
Medication: Co-codamol	2.1	2.5	4.7	-0.4	-2.2
Heart attack	2.1	2.6	5.0	-2.2	-0.5
Pain all over the body in last month	2.1	2.3	4.0	-2.0	0.7
Hayfever/allergic rhinitis (self-reported)	2.1	2.8	4.4	2.1	1.1
Medication: Cholesterol lowering	2.1	3.3	6.6	-2.6	0.2
Wheeze or whistling in the chest in last year	2.1	3.7	5.2	-1.5	2.3
Heart attack/myocardial infarction (self-reported)	2.1	2.7	5.2	-2.3	-0.4
Respiratory disease	2.0	4.4	4.6	-2.0	2.1
Angina	2.0	2.7	3.2	-1.5	1.8
Fractured/broken bones in last 5 years	2.0	2.6	4.7	-2.2	0.7
Blood Red Count	1.9	18.6	27.0	-5.2	-3.2
Coronary Artery Disease (CAD)	1.8	2.1	2.5	-1.3	1.6
Hand grip strength (right)	1.8	4.9	6.6	2.6	-1.8
Age when periods started (menarche)	1.8	4.4	8.7	3.0	-0.2
Fluid intelligence score	1.8	3.7	3.8	1.9	1.9
Falls in the last year	1.8	2.4	4.8	-0.1	-2.2
Asthma (self-reported)	1.8	3.6	3.9	-1.8	2.0
High blood pressure (mother)	1.7	2.3	4.6	-2.2	0.1
Neuroticism score	1.7	3.6	6.8	-2.6	0.6
Mouth/teeth dental problems: Dentures	1.7	2.8	3.8	-2.0	1.4
Medication: Lansoprazole	1.7	2.0	3.9	-2.0	0.1
Medication for pain relief, constipation, heartburn	1.7	2.9	5.5	2.3	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.7	2.0	3.7	1.9	-0.6
Smoking status: Current	1.7	2.7	3.9	2.0	1.3
Age started oral contraceptive pill	1.7	2.1	4.2	-2.0	-0.3
Neuroticism (2016)	1.6	2.3	4.1	-2.0	0.7
Sensitivity / hurt feelings	1.6	2.7	5.0	-2.2	0.7
Maternal smoking around birth	1.6	2.4	3.2	-1.2	1.8
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.5	6.5	-2.5	0.8
Medication: Atenolol	1.6	2.0	3.2	-1.8	-0.9
Medication: Omeprazole (e.g. Zanprol)	1.6	1.9	3.6	-0.5	1.9
Asthma	1.5	2.9	3.0	-1.7	1.7
Hypertension (Self-reported)	1.5	4.3	8.2	-2.9	-0.6
Intelligence (Savage-Jansen 2018)	1.4	4.4	8.3	2.9	-0.8
Mean Putamen Volume	1.4	1.6	3.2	-0.2	-1.8
Current tobacco smoking	1.4	2.3	3.7	1.9	1.0
Alcohol intake versus 10 years previously	1.4	2.1	2.4	-1.3	1.6
Tense / ‘highly strung’	1.4	2.3	2.7	-1.6	1.4
Commuting to job workplace: Car/motor vehicle	1.4	1.6	2.3	1.5	-0.9
Ever had bowel cancer screening	1.4	1.7	3.3	-1.8	0.0
Cholesterol lowering medication	1.4	2.1	3.1	-1.8	1.0
Supplements: Zinc	1.3	1.4	2.7	1.6	-0.1
Multivitamins +/- minerals	1.3	1.6	2.5	-0.9	1.6
Had menopause	1.3	1.7	3.3	-0.2	-1.8
Medication: Paracetamol	1.3	2.2	3.9	-2.0	-0.8
Gout (self-reported)	1.3	1.8	2.7	-1.7	0.9
Chronic bronchitis/emphysema (mother)	1.3	1.6	2.8	-0.5	1.7
Heart disease (mother)	1.3	1.5	3.0	-1.7	0.2
Family relationship satisfaction	1.3	1.6	3.1	1.8	0.1
Illnesses of siblings: Diabetes	1.3	1.6	2.5	-0.8	1.6
Medication: Paracetamol	1.3	2.0	3.1	-1.8	-0.9
Vascular/heart problems diagnosed by doctor	1.3	3.7	7.3	2.7	-0.2
Neuroticism	1.2	3.0	5.8	-2.4	0.4
High blood pressure	1.2	3.2	6.4	-2.5	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	4.0	-2.0	1.2
Mouth/teeth dental problems	1.2	1.9	3.1	1.8	-0.9
Number of full brothers	1.2	1.5	2.3	-1.5	0.8
Average weekly red wine intake	1.2	1.7	3.3	1.8	0.4
Medication: Atorvastatin	1.2	1.5	3.0	1.7	0.2
Pack years of smoking	1.2	1.8	3.0	-1.7	0.7
Alzheimer’s Disease (in father)	1.1	1.2	2.1	-1.4	0.5
Major Depression (MDD)	1.1	1.3	2.4	0.5	-1.5
Chronotype (morning person)	1.1	2.6	5.1	-2.3	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.5	2.1	-1.4	1.0
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	1.7	0.8	-1.3
Qualifications: None of the above	1.1	2.3	4.5	-2.1	0.2
Father’s age at death	1.1	1.5	1.7	1.3	-1.1
Worrier / anxious feelings	1.1	2.2	4.1	-2.0	0.5
Peak expiratory flow (PEF)	1.1	2.5	3.9	2.0	-1.1
High blood pressure (siblings)	1.1	1.5	2.6	-1.6	0.7
Supplements: Vitamin C	1.1	1.3	2.4	-0.3	1.6
Mood swings	1.1	2.0	2.6	-1.6	1.2
Long-standing illness, disability or infirmity	1.1	1.7	2.4	-1.0	1.5
Smoking Status	1.0	2.4	4.8	0.4	2.2
Pack years adult smoking proportion	1.0	1.5	2.4	-1.6	0.8
Townsend deprivation index at recruitment	1.0	1.4	2.3	0.7	-1.5
Medication: Levothyroxine sodium	1.0	1.7	1.8	1.4	1.2
Ever highly irritable/argumentative for 2 days	1.0	1.1	2.2	0.2	-1.5
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	2.9	1.0	1.7
Alcohol intake frequency.	1.0	2.3	4.2	-2.0	-0.7
Breast cancer (self-reported)	1.0	1.1	1.7	-1.3	0.8
Diastolic blood pressure, automated reading	1.0	3.0	5.5	-2.4	-0.7
Alcohol drinker status: Previous	1.0	1.1	1.8	-0.6	-1.3
Verbal and Numeric Reasoning (VNR)	0.9	2.1	4.1	2.0	0.2
Lupus	0.9	1.4	2.5	0.5	1.6
BMI	0.9	5.4	6.1	-2.2	-2.5
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	1.1	-0.9	-1.0
Chronic bronchitis/emphysema (father)	0.9	1.1	2.1	1.4	-0.3
Impedance of leg (left)	0.9	4.2	4.7	2.2	1.9
Impedance of arm (right)	0.9	4.0	6.2	2.5	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.4	2.0	-1.4	-0.9
Migraine (self-reported)	0.9	1.1	2.2	-0.3	-1.5
Overall health rating	0.9	2.0	4.0	-2.0	0.2
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.2	0.3	1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	3.2	1.8	0.6
Friendships satisfaction	0.9	1.2	1.8	1.3	-0.7
Eye problems/disorders: Cataract	0.9	1.1	1.4	-0.9	-1.2
Number of self-reported non-cancer illnesses	0.9	1.5	1.7	-1.1	1.3
Myopia	0.9	1.3	1.7	1.3	0.9
Impedance of whole body	0.9	4.8	5.6	2.4	2.0
HDL Cholesterol	0.8	1.3	2.6	0.3	1.6
Triglycerides	0.8	1.3	1.4	-1.2	-1.1
Hand grip strength (left)	0.8	2.0	2.9	1.7	-1.1
Average weekly spirits intake	0.8	1.1	1.2	-1.0	1.1
Vitamin and mineral supplements	0.8	1.0	1.7	0.6	-1.3
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	1.1	0.9	1.1
Body mass index (BMI)	0.8	3.2	4.0	-2.0	-1.5
Hearing difficulty/problems with background noise	0.8	1.3	2.6	-1.6	0.0
Allergy	0.8	1.8	3.6	0.2	-1.9
Impedance of arm (left)	0.8	3.6	4.3	2.1	1.7
Pulse wave reflection index	0.8	1.0	2.0	-0.2	-1.4
Mouth/teeth dental problems: Bleeding gums	0.8	1.1	1.1	-1.1	-1.0
Worry too long after embarrassment	0.8	1.4	1.7	-1.0	-1.3
Age at first live birth	0.8	1.5	2.8	-0.5	1.7
Qualifications: College or University degree	0.8	2.5	5.0	2.2	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	1.6	-0.4	-1.3
Mineral and other dietary supplements	0.8	1.1	1.3	1.0	-1.1
Osteoarthritis (self-reported)	0.8	1.0	2.0	-1.4	-0.2
Supplements: Fish oil (including cod liver oil)	0.8	1.1	1.1	-1.0	1.1
Fasting Glucose	0.7	0.8	0.9	-0.9	-0.9
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.4	0.6	-1.2
Impedance of leg (right)	0.7	3.5	4.0	1.7	2.0
Taking other prescription medications	0.7	1.1	1.8	-1.4	0.6
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	0.9	0.8	-1.0
Exposure to tobacco smoke outside home	0.7	0.9	1.4	-1.2	0.6
Knee pain experienced in last month	0.7	1.1	2.1	-1.4	-0.4
Back pain experienced in last month	0.7	1.1	2.0	-1.4	-0.3
Ever taken oral contraceptive pill	0.7	0.7	1.5	0.2	-1.2
Illnesses of father: High blood pressure	0.7	0.8	1.7	-1.3	-0.1
Basal cell carcinoma (self-reported)	0.7	0.8	1.3	-1.1	0.5
Ulcerative Colitis	0.6	0.9	1.7	1.3	0.3
Lung FEV1/FVC ratio	0.6	2.8	5.1	-0.7	-2.3
Medication for hormone replacement therapy	0.6	0.7	0.9	0.9	0.7
Waist circumference	0.6	2.2	4.3	-2.1	-0.2
Number of incorrect matches in round	0.6	1.0	1.8	-1.3	0.4
Number of live births	0.6	0.9	1.7	0.3	-1.3
Birth weight	0.6	1.2	1.4	1.0	-1.2
Health satisfaction	0.6	0.8	1.6	-0.2	1.3
Neck or shoulder pain in last month	0.6	0.9	1.1	0.8	1.1
Medication: Omeprazole	0.6	0.7	1.4	-0.0	1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	1.0	-1.0	0.6
Alcohol drinker status: Never	0.6	0.8	1.5	0.1	1.2
Risk taking	0.6	0.8	1.5	-0.3	-1.2
Unable to work because of sickness or disability	0.6	0.7	0.9	-0.7	0.9
Breast Cancer	0.5	1.2	2.1	-1.4	-0.6
HbA1C	0.5	0.6	0.6	0.8	0.7
Blood White Count	0.5	3.7	5.7	2.4	1.3
Cardiovascular Disease	0.5	1.6	3.2	-1.8	0.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.3	0.4	-1.1
Severe depression (siblings)	0.5	0.5	0.7	-0.6	0.8
Serious illness, injury or assault to yourself	0.5	0.6	0.7	-0.9	0.6
Hayfever, allergic rhinitis or eczema	0.5	1.0	2.0	0.0	1.4
Hip circumference	0.5	2.2	4.0	-2.0	-0.5
Hair/balding pattern: Pattern 3	0.5	0.7	1.0	1.0	-0.7
Forced expiratory volume in 1-second (FEV1)	0.5	1.8	2.2	1.5	-1.1
Pulse rate	0.5	0.8	1.5	-0.5	1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	0.9	0.6	0.9
Medication: Allopurinol	0.5	0.7	1.4	-1.2	0.3
Leg fat mass (right)	0.5	1.9	3.7	-1.9	0.0
Pulse rate, automated reading	0.5	1.5	3.0	-0.3	1.7
Number of full sisters	0.5	0.6	1.0	1.0	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	2.1	-0.3	-1.5
Medication: Blood pressure	0.5	1.0	1.8	-1.4	-0.3
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.2	0.1	-1.1
Schizophrenia (2018)	0.4	0.8	0.9	0.9	0.9
Age at First Birth	0.4	0.6	0.6	-0.7	0.8
Schizophrenia (2014)	0.4	0.8	1.6	-0.2	1.3
Allergy or Eczema	0.4	0.9	1.1	-0.9	1.0
Type 2 Diabetes (T2D) (2018)	0.4	0.8	1.5	0.4	1.2
Supplements: Glucosamine	0.4	0.5	0.7	-0.8	0.6
Sitting height	0.4	2.7	5.3	0.1	2.3
Alcohol usually taken with meals	0.4	0.6	1.1	1.1	0.0
Forced vital capacity (FVC)	0.4	1.4	2.8	1.7	0.0
Financial difficulties in last 2 years	0.4	0.6	1.0	-1.0	-0.4
Weight	0.4	1.8	3.2	-1.8	-0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.9	1.2	1.1	0.8
Pulse wave Arterial Stiffness index	0.4	0.5	0.6	0.6	0.8
Arm fat mass (right)	0.4	1.7	2.9	-1.7	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	1.0	1.0	0.5
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.0	1.0	-0.5
Leg fat percentage (right)	0.4	1.4	2.7	-1.6	-0.2
Arm fat-free mass (right)	0.4	1.8	3.6	-1.9	-0.1
Emphysema/chronic bronchitis	0.4	0.5	0.6	0.6	0.8
Had major operations	0.4	0.4	0.8	0.9	0.3
Arm fat percentage (left)	0.4	1.6	2.8	-1.7	-0.6
Handedness (chirality/laterality): Left-handed	0.4	0.5	0.9	0.2	0.9
Loneliness, isolation	0.4	0.5	1.0	0.2	-1.0
Diabetes diagnosed by doctor	0.4	0.7	1.1	-0.6	1.0
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	0.9	0.7	-1.0
Arm fat mass (left)	0.4	1.8	3.2	-1.8	-0.7
Average weekly champagne plus white wine intake	0.4	0.5	0.6	0.7	0.8
Financial situation satisfaction	0.4	0.5	0.8	-0.4	0.9
High cholesterol (Self-reported)	0.4	0.7	1.2	-1.1	0.4
Ever had prostate specific antigen (PSA) test	0.4	0.5	0.6	-0.6	-0.8
Leg fat mass (left)	0.4	1.6	3.1	-1.8	-0.1
Bipolar Disorder or Schizophrenia	0.3	0.6	1.1	0.4	1.1
Schizophrenia vs Biploar Disorder	0.3	0.4	0.6	-0.8	0.3
Ulcerative Colitis (UC)	0.3	0.6	0.6	0.8	-0.8
LDL Cholesterol	0.3	0.4	0.8	-0.3	0.9
Type 2 Diabetes (T2D) (2012)	0.3	0.4	0.6	-0.4	-0.8
Blood Platelet Count	0.3	3.1	5.6	2.4	0.8
Heel T-Score	0.3	2.4	2.6	-1.5	1.6
Height	0.3	5.3	10.3	0.5	3.2
Systolic Blood Pressure	0.3	1.6	3.0	-1.7	-0.4
Hearing difficulty/problems: Yes	0.3	0.4	0.8	-0.9	-0.1
Average weekly fortified wine intake	0.3	0.4	0.6	0.2	-0.8
Relative age voice broke	0.3	0.5	0.6	0.8	0.7
Trunk fat mass	0.3	1.3	2.6	-1.6	-0.0
Past tobacco smoking	0.3	0.5	0.9	-0.0	-1.0
Hair/balding pattern: Pattern 2	0.3	0.4	0.8	0.9	0.1
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	0.4	0.6	0.6
Arm fat percentage (right)	0.3	1.3	2.3	-1.5	-0.6
Happiness	0.3	0.4	0.7	0.8	-0.3
Breastfed as a baby	0.3	0.4	0.7	0.3	-0.8
Hair/balding pattern: Pattern 4	0.3	0.8	1.4	-1.2	0.4
Loud music exposure frequency	0.3	0.3	0.6	0.0	0.8
Medication: Amlodipine	0.3	0.4	0.8	-0.3	-0.9
Mouth/teeth dental problems: Loose teeth	0.3	0.4	0.5	-0.5	0.7
Medication: Seretide 50 evohaler	0.3	0.3	0.5	-0.7	0.2
Mean time to correctly identify matches	0.3	0.6	0.9	-0.9	-0.5
Whole body fat mass	0.3	1.3	2.6	-1.6	-0.3
Arm predicted mass (right)	0.3	1.6	2.8	-1.7	-0.5
Wears glasses or contact lenses	0.3	0.4	0.6	0.3	-0.8
Mother’s age at death	0.3	0.4	0.7	-0.8	-0.0
Commuting to job workplace: Public transport	0.3	0.4	0.7	-0.8	-0.3
Medication: Bendroflumethiazide	0.3	0.5	1.1	-0.0	-1.0
Ever smoked	0.3	0.6	1.0	-0.4	1.0
Leg fat percentage (left)	0.3	0.9	1.8	-1.3	-0.3
Average weekly beer plus cider intake	0.3	0.5	0.9	-0.2	-1.0
Supplements: Calcium	0.3	0.3	0.4	0.4	0.7
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	0.8	-0.9	-0.0
Bipolar Disorder (2018)	0.2	0.3	0.3	-0.5	0.5
Irritable Bowel Disease (IBD)	0.2	0.5	0.6	0.6	-0.8
Rheumatoid Arthritis	0.2	0.3	0.4	-0.6	0.5
Waist Hip Ratio (WHR)	0.2	0.9	1.7	1.3	0.3
Hypothyroidism (self reported)	0.2	0.5	0.8	0.9	0.4
Leg fat-free mass (left)	0.2	0.9	1.8	-1.4	-0.3
Trunk fat percentage	0.2	0.7	1.4	-1.2	-0.1
Leg predicted mass (left)	0.2	0.9	1.8	-1.3	-0.3
Diabetes (self-reported)	0.2	0.4	0.7	0.2	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.4	0.1	-0.6
Prospective memory result	0.2	0.3	0.4	0.6	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.8	0.9	0.9	-0.8
Standing height	0.2	1.5	2.6	0.7	1.6
Blood clot in the leg (DVT)	0.2	0.3	0.6	-0.8	0.0
Forced vital capacity (FVC), Best measure	0.2	0.9	1.7	1.3	0.3
Body fat percentage	0.2	0.9	1.8	-1.3	-0.2
Comparative body size at age 10	0.2	0.6	1.1	-1.0	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	0.3	0.3	0.6
Pulse wave peak to peak time	0.2	0.2	0.3	-0.3	-0.6
Suffer from ‘nerves’	0.2	0.3	0.4	-0.4	0.6
Illnesses of father: Heart disease	0.2	0.3	0.6	-0.2	-0.8
Smoking status: Previous	0.2	0.3	0.3	-0.5	0.5
Whole body fat-free mass	0.2	1.1	2.0	-1.4	-0.4
Leg fat-free mass (right)	0.2	0.8	1.4	-1.2	-0.4
Medication for cholesterol	0.2	0.2	0.3	0.5	-0.5
Illnesses of father: None of the above (group 1)	0.2	0.3	0.4	0.5	-0.6
Whole body water mass	0.2	1.1	1.9	-1.4	-0.5
Leg predicted mass (right)	0.2	0.9	1.5	-1.2	-0.5
Hearing aid user	0.2	0.2	0.4	0.1	-0.7
Basal metabolic rate	0.2	1.2	2.2	-1.5	-0.3
Arm fat-free mass (left)	0.2	0.9	1.8	-1.3	-0.3
Ever depressed for a whole week	0.2	0.2	0.4	0.2	0.6
Arm predicted mass (left)	0.2	0.8	1.5	-1.2	-0.2
Crohns Disease (2017)	0.1	0.3	0.5	0.2	-0.7
Reaction Time	0.1	0.1	0.2	0.2	-0.4
Body Mass Index (BMI) (2010)	0.1	0.2	0.2	-0.5	-0.3
Blood Eosinophil Count	0.1	0.7	0.7	0.8	0.8
Lung FVC	0.1	0.3	0.4	0.5	-0.7
Systolic blood pressure, automated reading	0.1	0.4	0.8	-0.9	-0.1
Stomach or abdominal pain in last month	0.1	0.1	0.2	0.4	0.3
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.3	-0.2	-0.5
Had other major operations	0.1	0.1	0.3	-0.5	-0.1
Trunk fat-free mass	0.1	0.8	1.4	-1.2	-0.3
Time employed in main current job	0.1	0.1	0.2	0.0	0.4
Noisy workplace	0.1	0.2	0.2	-0.5	-0.4
Depression (self-reported)	0.1	0.1	0.1	-0.4	-0.3
Trunk predicted mass	0.1	0.8	1.5	-1.2	-0.3
Headache pain in last month	0.1	0.1	0.2	0.4	-0.2
Comparative height size at age 10	0.1	0.8	1.6	-0.0	-1.3
Qualifications: nursing, teaching	0.1	0.2	0.4	0.6	-0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.1	-0.1	0.3
Medication: Gliclazide	0.1	0.1	0.2	0.4	0.2
Guilty feelings	0.1	0.1	0.2	-0.5	0.2
Irritability	0.1	0.2	0.3	-0.5	-0.3
Commuting to job workplace: Cycle	0.1	0.2	0.3	0.5	0.3
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.9	1.8	1.3	0.3
Tanning	0.0	0.1	0.1	0.3	-0.2
Frequency of depressed mood in last 2 weeks	0.0	0.1	0.1	-0.2	-0.3
Medication: Metformin	0.0	0.0	0.1	-0.1	0.3
Diabetes (father)	0.0	0.0	0.1	-0.0	0.2
Diabetes (mother)	0.0	0.0	0.1	-0.2	0.1
Lung cancer (father)	0.0	0.0	0.1	-0.3	0.1
Birth weight of first child	0.0	0.0	0.0	0.2	0.1
Medication: Ibuprofen	0.0	0.0	0.0	-0.1	-0.1
Age at last live birth	0.0	0.1	0.1	-0.0	0.3
Leg pain on walking	0.0	0.0	0.0	-0.2	0.0
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.1	0.1	-0.2	-0.2
Number of operations (self-reported)	0.0	0.0	0.1	0.1	-0.3
Pain experienced in last month	0.0	0.1	0.1	0.3	0.1

Hub : Genes

SLC35B2

Models

Trait associations