TWAS hub - SLC38A3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	ROSMAP	Brain Pre-frontal Cortex	0.033	0.0182	0.0012	0.027	0.020	0.019	0.018	0.022	0.00016	0.0011	0.0016	0.0019	0.00064
2	TCGA	Thyroid Carcinoma	0.028	0.0190	0.0034	0.020	0.017	0.015	NA	0.014	0.00450	0.0073	0.0110	NA	0.01600

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Qualifications: College or University degree	31.9	100.6	123.2	11.1	8.8
Age at last live birth	23.7	34.3	35.9	5.7	6.0
Age at First Birth	22.7	32.9	33.5	5.8	5.7
Qualifications: A levels/AS levels or equivalent	22.2	49.1	58.8	7.7	6.3
Average weekly beer plus cider intake	21.5	31.1	31.5	-5.5	-5.6
Age at first live birth	21.2	37.6	39.7	6.0	6.3
Taking other prescription medications	19.9	30.7	33.1	-5.8	-5.3
Body mass index (BMI)	19.4	82.5	85.6	-9.2	-8.9
Ever highly irritable/argumentative for 2 days	19.1	22.9	25.9	-5.1	-4.5
Overall health rating	18.8	40.4	49.9	-7.1	-5.6
Leg pain on walking	18.4	23.1	23.4	-4.8	-4.8
Leg fat mass (right)	18.3	71.0	78.9	-8.9	-8.0
Leg fat mass (left)	18.2	71.1	78.9	-8.9	-8.0
Intelligence (Savage-Jansen 2018)	17.7	54.2	59.8	7.7	7.0
Arm fat mass (left)	16.0	65.6	70.4	-8.4	-7.8
Arm fat mass (right)	15.7	64.7	71.2	-8.4	-7.6
BMI	15.6	90.2	94.5	-9.7	-9.3
Qualifications: None of the above	15.3	32.8	43.8	-6.6	-4.7
Alcohol intake versus 10 years previously	15.2	22.8	25.9	-5.1	-4.4
Leg fat percentage (right)	15.2	54.9	62.7	-7.9	-6.9
Miserableness	15.0	25.9	30.3	-5.5	-4.6
Ulcerative Colitis	14.7	21.4	26.6	5.2	4.0
Wheeze or whistling in the chest in last year	14.7	26.2	27.2	-5.0	-5.2
Whole body fat mass	14.7	61.5	69.6	-8.3	-7.3
Number of operations (self-reported)	14.7	21.9	23.5	-4.8	-4.5
Weight	14.3	70.4	73.8	-8.6	-8.2
Impedance of arm (right)	14.2	66.4	69.4	8.0	8.3
Knee pain experienced in last month	14.2	22.1	23.1	-4.6	-4.8
Ulcerative Colitis (UC)	14.1	26.5	33.7	5.8	4.4
Number of treatments/medications taken	14.1	25.3	31.3	-5.6	-4.4
Leg fat percentage (left)	14.1	51.1	59.4	-7.7	-6.5
Chronotype (morning person)	14.0	32.4	40.1	6.3	5.0
Age when periods started (menarche)	14.0	33.5	33.6	-5.8	-5.8
Impedance of arm (left)	13.7	63.4	64.2	7.9	8.0
Irritable Bowel Disease (IBD)	13.3	31.7	42.1	6.5	4.6
Chronic bronchitis/emphysema (mother)	12.8	14.9	16.0	-3.7	-4.0
Waist circumference	12.6	46.0	49.5	-7.0	-6.5
Arm predicted mass (left)	12.6	64.2	66.1	-8.1	-7.9
Verbal and Numeric Reasoning (VNR)	12.3	29.6	32.1	5.7	5.2
Schizophrenia vs Biploar Disorder	12.1	16.0	22.0	4.7	3.2
Fluid intelligence score	12.1	25.2	29.0	5.4	4.6
Ever had hysterectomy (womb removed)	12.0	13.5	16.4	-3.3	-4.1
Arm fat-free mass (left)	11.9	60.2	61.9	-7.9	-7.6
Ever unenthusiastic/disinterested for a whole week	11.7	14.3	15.5	-3.9	-3.6
Medication: Omeprazole	11.5	13.7	15.5	-3.9	-3.5
Arm predicted mass (right)	11.5	58.8	60.1	-7.8	-7.6
Exposure to tobacco smoke outside home	11.4	15.2	15.6	-4.0	-3.8
Impedance of whole body	11.4	58.2	64.3	7.2	8.0
Mouth/teeth dental problems: Dentures	11.3	19.0	23.9	-4.9	-3.8
Trunk fat mass	10.9	46.7	52.4	-7.2	-6.4
Arm fat-free mass (right)	10.9	56.1	57.9	-7.4	-7.6
Medication: Co-codamol	10.8	12.5	14.8	-3.9	-3.2
Arm fat percentage (right)	10.7	42.2	47.8	-6.9	-6.0
Arm fat percentage (left)	10.7	42.7	46.7	-6.8	-6.2
Pain experienced in last month	10.6	17.7	19.7	4.4	4.0
Number of live births	10.5	14.8	17.1	-3.5	-4.1
Basal metabolic rate	10.4	57.5	58.1	-7.6	-7.5
Body fat percentage	10.2	40.2	46.6	-6.8	-5.8
Medication: Ventolin 100micrograms inhaler	9.8	12.5	14.4	-3.8	-3.3
Asthma (self-reported)	9.6	19.0	22.1	-4.0	-4.7
Respiratory disease	9.3	20.6	22.1	-4.4	-4.7
Depressed Affect (Nagel 2018)	9.2	19.4	22.4	-4.7	-4.1
Hip circumference	9.2	39.5	41.5	-6.4	-6.1
Leg predicted mass (left)	9.1	48.3	49.4	-6.9	-7.0
Leg fat-free mass (left)	9.0	47.9	48.9	-6.8	-7.0
Shortness of breath walking on level ground	8.9	10.6	12.1	-3.0	-3.5
Alcohol intake frequency.	8.9	20.7	25.1	-5.0	-4.0
Had other major operations	8.8	10.8	14.2	-2.7	-3.8
Asthma	8.8	17.4	20.0	-3.8	-4.5
Bilateral oophorectomy (both ovaries removed)	8.7	10.1	11.6	-2.9	-3.4
Osteoarthritis (self-reported)	8.7	11.3	12.6	-3.5	-3.1
Fed-up feelings	8.6	15.6	20.7	-4.5	-3.2
Whole body water mass	8.5	48.7	49.9	-6.9	-7.1
Exposure to tobacco smoke at home	8.3	9.3	12.2	-3.5	-2.5
Number of children fathered	8.3	9.4	11.0	-3.3	-2.8
Whole body fat-free mass	8.3	47.3	48.6	-6.8	-7.0
Crohns Disease (2012)	8.2	13.2	17.1	4.1	3.0
Ever had bowel cancer screening	8.2	9.6	10.4	3.2	3.0
Illnesses of siblings: Diabetes	7.9	9.7	11.9	-3.5	-2.7
Neck or shoulder pain in last month	7.8	11.1	12.7	-3.6	-3.1
Chest pain or discomfort	7.8	11.3	13.2	-3.6	-3.1
Qualifications: nursing, teaching	7.8	12.2	18.6	4.3	2.4
Commuting to job workplace: Walk	7.7	8.3	9.6	3.1	2.6
Relative age of first facial hair	7.6	15.6	17.1	-3.8	-4.1
Noisy workplace	7.6	9.4	11.5	-3.4	-2.7
Leg fat-free mass (right)	7.5	40.0	41.5	-6.2	-6.4
Medication: Omeprazole (e.g. Zanprol)	7.5	9.1	9.9	-3.1	-2.9
Trunk fat percentage	7.4	29.6	35.0	-5.9	-4.9
Qualifications: CSEs or equivalent	7.4	9.8	10.0	-3.1	-3.2
Pain type(s) experienced in last month: Hip pain	7.4	9.4	12.3	-2.5	-3.5
Mood swings	7.3	13.2	13.7	-3.7	-3.6
Leg predicted mass (right)	7.3	39.2	40.7	-6.1	-6.4
Trunk fat-free mass	7.2	41.1	42.4	-6.3	-6.5
Qualifications: NVQ or HND or HNC or equivalent	7.2	8.7	10.0	-2.7	-3.2
Commuting to job workplace: Car/motor vehicle	7.2	8.2	10.8	-3.3	-2.4
Crohns Disease (2017)	7.1	15.5	22.9	4.8	2.9
Ever depressed for a whole week	7.1	8.7	9.6	-3.1	-2.8
Frequency of tenseness / restlessness in last 2 weeks	7.0	10.9	13.1	-3.6	-2.9
Maternal smoking around birth	6.9	10.0	13.0	-2.6	-3.6
Trunk predicted mass	6.8	38.6	39.5	-6.1	-6.3
Impedance of leg (left)	6.6	32.1	39.3	5.0	6.3
Medication: Seretide 50 evohaler	6.6	7.5	10.2	-3.2	-2.2
Number of full brothers	6.5	8.2	10.2	-3.2	-2.5
Number of self-reported non-cancer illnesses	6.4	11.1	13.1	-3.6	-3.0
Type 2 Diabetes (T2D) (2018)	6.3	11.8	12.9	-3.6	-3.3
Pain all over the body in last month	6.3	6.7	7.7	-2.8	-2.4
Number of full sisters	6.3	7.7	8.9	-2.5	-3.0
Long-standing illness, disability or infirmity	6.1	9.3	10.0	-2.9	-3.2
Medication: Paracetamol	6.0	9.2	13.1	-3.6	-2.3
Smoking Status	5.8	13.8	14.5	-3.6	-3.8
Average weekly red wine intake	5.8	8.6	11.8	3.4	2.3
Prostate Cancer	5.7	8.0	13.0	-3.6	-1.7
Body Mass Index (BMI) (2010)	5.7	7.8	9.2	-2.5	-3.0
HDL Cholesterol	5.5	9.1	11.4	3.4	2.6
Seen doctor (GP) for nerves, anxiety, tension or depression	5.5	8.4	8.9	-3.0	-2.8
Loneliness, isolation	5.5	7.6	9.2	-3.0	-2.4
Impedance of leg (right)	5.4	26.0	31.7	4.5	5.6
Diabetes (self-reported)	5.4	8.3	10.3	-3.2	-2.5
Medication: Paracetamol	5.3	8.8	13.0	-3.6	-2.1
Financial situation satisfaction	5.3	6.6	7.6	-2.4	-2.8
Bipolar Disorder (2018)	5.2	8.3	8.6	-2.8	-2.9
Frequency of unenthusiasm / disinterest in last 2 weeks	5.2	7.0	8.0	-2.8	-2.4
Mouth/teeth dental problems	5.2	7.9	9.0	2.6	3.0
Hair/balding pattern: Pattern 2	5.1	6.5	7.2	-2.4	-2.7
Health satisfaction	5.1	6.7	7.3	-2.5	-2.7
Chronic bronchitis/emphysema (father)	5.0	5.9	7.8	-2.8	-2.0
Medication for hormone replacement therapy	4.9	5.4	6.9	-2.0	-2.6
Basal cell carcinoma (self-reported)	4.9	5.8	6.8	2.6	2.2
Lupus	4.8	7.3	8.8	-2.4	-3.0
Ever used hormone-replacement therapy (HRT)	4.8	6.1	6.7	-2.3	-2.6
Neuroticism	4.6	11.1	14.6	-3.8	-2.8
Medication: Atenolol	4.5	5.6	7.2	-2.7	-2.0
Neuroticism score	4.5	9.4	13.4	-3.7	-2.3
Age started oral contraceptive pill	4.5	5.6	5.8	2.4	2.4
Blood Eosinophil Count	4.3	33.0	38.3	-6.2	-5.3
Medication: Lansoprazole	4.3	4.8	5.6	-2.0	-2.4
Had major operations	4.3	5.1	8.7	-3.0	-1.2
Diabetes (father)	4.1	5.1	6.8	-2.6	-1.9
Commuting to job workplace: Public transport	4.1	4.9	5.5	2.1	2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	4.0	4.7	5.4	-2.3	-2.0
Diastolic blood pressure, automated reading	4.0	12.5	13.5	-3.7	-3.4
Medication: Ibuprofen (e.g. Nurofen)	3.9	5.0	5.2	-2.2	-2.3
Diabetes diagnosed by doctor	3.8	6.2	7.5	-2.7	-2.2
Guilty feelings	3.8	5.7	8.0	-2.8	-1.9
Frequency of depressed mood in last 2 weeks	3.7	5.2	6.2	-2.5	-2.0
Frequency of tiredness / lethargy in last 2 weeks	3.7	6.0	6.9	-2.6	-2.3
Prospective memory result	3.7	4.5	4.9	-2.2	-2.0
Average weekly champagne plus white wine intake	3.7	5.0	7.2	2.7	1.7
Current tobacco smoking	3.6	5.9	7.1	-2.7	-2.1
Tinnitus: Yes, but not now, but have in the past	3.6	3.8	4.7	-2.2	-1.7
Allergy	3.6	8.2	11.4	2.2	3.4
Hair/balding pattern: Pattern 3	3.6	5.3	7.5	1.8	2.7
Neuroticism (Nagel 2018)	3.5	8.1	11.4	-3.4	-2.2
Coronary Artery Disease (CAD)	3.4	4.1	5.2	-2.3	-1.7
Medication for cholesterol, blood pressure or diabetes	3.4	5.6	5.9	2.3	2.4
Glaucoma (self-reported)	3.4	4.0	4.7	2.2	1.8
Medication: Blood pressure	3.4	6.0	6.7	-2.3	-2.6
Medication for pain relief, constipation, heartburn	3.3	5.7	7.7	2.8	1.9
Commuting to job workplace: Cycle	3.3	4.0	4.4	2.1	1.9
Medication: Ibuprofen	3.2	3.9	4.6	-1.8	-2.1
Blood White Count	3.1	23.1	33.6	-5.8	-3.5
Lung cancer (father)	3.1	3.7	3.9	-2.0	-1.9
Blood clot in the leg (DVT)	3.1	4.0	4.9	-2.2	-1.7
Friendships satisfaction	3.1	3.9	4.3	2.1	1.8
Qualifications: O levels/GCSEs or equivalent	3.0	4.8	5.1	2.2	2.1
High blood pressure (siblings)	3.0	4.4	5.1	-2.3	-1.9
Smoking status: Current	3.0	4.7	5.7	-2.4	-1.9
Pulse wave reflection index	2.9	3.6	3.6	-1.9	-1.9
Seen a psychiatrist for nerves, anxiety, tension or depression	2.9	3.7	4.3	-1.8	-2.1
Worry too long after embarrassment	2.8	4.6	5.3	2.0	2.3
Handedness (chirality/laterality): Left-handed	2.8	3.4	3.6	1.8	1.9
Breast cancer (self-reported)	2.8	3.3	4.3	-1.5	-2.1
Deep venous thrombosis (DVT) (self-reported)	2.8	3.6	4.7	-2.2	-1.6
Mother’s age at death	2.7	3.4	3.5	1.9	1.8
Heart attack	2.6	3.3	3.5	-1.8	-1.9
Depression (self-reported)	2.6	3.1	3.2	-1.7	-1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.6	5.5	8.2	2.9	1.7
Depression (Nagel 2018)	2.4	3.7	4.7	-2.2	-1.6
HbA1C	2.4	2.6	4.3	1.0	2.1
Past tobacco smoking	2.3	4.3	7.0	1.2	2.6
Father’s age at death	2.3	3.0	3.5	1.9	1.6
Alzheimer’s Disease (including proxy)	2.2	3.1	5.1	-1.1	-2.3
Hand grip strength (right)	2.2	6.0	7.7	-2.8	-2.1
Illnesses of siblings	2.2	3.2	3.3	1.7	1.8
Smoking status: Previous	2.2	3.2	5.5	-1.0	-2.3
Alcohol usually taken with meals	2.1	3.3	4.6	2.1	1.4
Falls in the last year	2.1	2.8	3.6	-1.4	-1.9
Comparative body size at age 10	2.1	5.9	7.6	-2.0	-2.8
Risk taking	2.1	3.1	3.9	-1.5	-2.0
Medication: Ramipril	2.0	2.6	3.3	-1.4	-1.8
Tense / ‘highly strung’	2.0	3.3	4.1	-2.0	-1.6
Mouth/teeth dental problems: Loose teeth	2.0	2.4	3.3	-1.2	-1.8
Back pain experienced in last month	2.0	2.9	3.6	-1.5	-1.9
Heart attack/myocardial infarction (self-reported)	2.0	2.5	2.8	-1.5	-1.7
Neuroticism (2016)	1.9	2.7	4.8	-2.2	-0.8
Alzheimer’s Disease (in mother)	1.8	2.1	3.0	-1.1	-1.7
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	3.4	1.9	0.9
Mean time to correctly identify matches	1.8	3.5	3.7	1.8	1.9
Ever taken oral contraceptive pill	1.8	2.0	3.6	-0.7	-1.9
Supplements: Fish oil (including cod liver oil)	1.8	2.3	2.9	1.7	1.3
Ever smoked	1.8	3.2	5.2	-1.1	-2.3
Average weekly spirits intake	1.7	2.1	3.7	-1.9	-0.7
Relative age voice broke	1.7	2.7	2.7	-1.6	-1.6
Breastfed as a baby	1.7	2.1	3.3	1.8	1.0
Mouth/teeth dental problems: Mouth ulcers	1.7	2.8	4.0	-1.2	-2.0
Heel bone mineral density (BMD) T-score, automated (left)	1.6	3.6	4.1	-2.0	-1.8
Stomach or abdominal pain in last month	1.6	2.0	2.5	-1.6	-1.2
Medication: Gliclazide	1.6	1.8	2.0	-1.4	-1.2
Pulse wave peak to peak time	1.5	1.8	2.3	1.5	1.1
Medication for cholesterol	1.5	2.3	2.5	1.6	1.5
Alcohol drinker status: Previous	1.5	1.7	2.8	-0.8	-1.7
Breast Cancer	1.4	3.5	4.0	2.0	1.7
Medication: Metformin	1.4	2.0	2.3	-1.3	-1.5
Bipolar Disorder or Schizophrenia	1.3	3.1	5.3	-1.0	-2.3
Worry (Nagel 2018)	1.2	2.5	4.4	-2.1	-0.8
Number of incorrect matches in round	1.2	2.1	3.9	2.0	0.5
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	3.8	-1.9	-1.3
Financial difficulties in last 2 years	1.2	1.6	3.1	-1.8	-0.4
Pulse wave Arterial Stiffness index	1.2	1.4	1.9	-1.4	-1.0
Migraine (self-reported)	1.2	1.5	1.5	-1.2	-1.2
Unable to work because of sickness or disability	1.2	1.5	1.7	-1.1	-1.3
Supplements: Calcium	1.2	1.3	1.7	1.3	1.0
Reaction Time	1.1	2.1	2.2	1.4	1.5
Primary Biliary Cirrhosis	1.1	1.5	2.0	1.0	1.4
Lung FVC	1.1	5.6	10.5	3.2	0.8
Medication: Cholesterol lowering	1.1	1.7	2.3	-1.1	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.4	2.0	1.4	0.9
Comparative height size at age 10	1.1	6.2	7.3	2.2	2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.5	-1.6	-0.4
Headache pain in last month	1.0	1.7	2.0	-1.4	-1.2
Forced vital capacity (FVC), Best measure	1.0	3.7	6.5	2.5	1.0
Wears glasses or contact lenses	0.9	1.0	1.5	-1.2	-0.7
Eye problems/disorders: Glaucoma	0.9	1.0	1.1	1.0	1.1
Major Depression (MDD)	0.8	1.0	2.0	-1.4	0.0
Sensitivity / hurt feelings	0.8	1.5	2.2	-1.5	-0.8
Severe depression (siblings)	0.7	0.7	1.0	-0.7	-1.0
Medication: Levothyroxine sodium	0.7	1.3	1.3	-1.1	-1.1
Forced vital capacity (FVC)	0.7	2.6	4.6	2.1	0.8
Time employed in main current job	0.7	0.8	1.1	1.0	0.8
Worrier / anxious feelings	0.7	1.4	2.7	-1.6	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.4	4.3	2.1	0.7
Birth weight of first child	0.7	1.3	2.6	1.6	-0.3
Heart disease (mother)	0.7	0.9	1.0	1.0	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	2.5	-0.6	-1.6
Medication: Atorvastatin	0.7	0.8	1.2	-1.1	-0.6
Supplements: Zinc	0.6	0.6	1.2	1.1	0.3
Nervous feelings	0.6	1.1	2.1	-1.5	0.2
High cholesterol (Self-reported)	0.6	1.0	1.2	0.9	1.1
Heel T-Score	0.5	4.1	4.9	-1.8	-2.2
Cardiovascular Disease	0.5	1.5	2.1	-1.5	-0.9
Pack years adult smoking proportion	0.5	0.8	1.0	-0.7	-1.0
Happiness	0.5	0.6	0.6	0.8	0.7
Peak expiratory flow (PEF)	0.5	1.2	2.3	1.5	0.3
Gout (self-reported)	0.5	0.7	1.1	-1.0	-0.5
Family relationship satisfaction	0.5	0.6	0.7	-0.6	-0.9
Supplements: Vitamin C	0.5	0.6	0.6	0.8	0.7
Medication: Aspirin	0.5	0.6	0.9	0.6	0.9
Cholesterol lowering medication	0.5	0.7	1.0	-1.0	-0.7
Mean Putamen Volume	0.4	0.4	0.9	-0.9	-0.1
Hypothyroidism (self reported)	0.4	0.8	1.1	-0.8	-1.1
Serious illness, injury or assault to yourself	0.4	0.5	0.9	1.0	-0.1
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	2.3	1.5	0.5
Pulse rate	0.4	0.6	0.9	0.6	1.0
Loud music exposure frequency	0.4	0.4	0.8	-0.2	0.9
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	1.0	-0.7	-1.0
Emphysema/chronic bronchitis	0.4	0.4	0.4	-0.7	-0.6
Medication: Aspirin	0.4	0.5	0.6	0.6	0.8
Mineral and other dietary supplements	0.4	0.5	0.9	-0.9	-0.3
Osteoporosis (self-reported)	0.4	0.5	1.0	-0.3	-1.0
Medication: Lisinopril	0.4	0.6	1.0	-1.0	-0.3
Irritability	0.4	0.7	1.2	-1.1	-0.5
Vascular/heart problems diagnosed by doctor	0.4	1.0	1.3	1.1	0.9
Heart disease (siblings)	0.4	0.5	0.9	0.2	0.9
Schizophrenia (2018)	0.3	0.7	1.0	1.0	-0.6
Alzheimer’s Disease (in father)	0.3	0.3	0.4	-0.5	-0.6
Ovarian Cancer	0.3	0.4	0.7	0.3	0.8
LDL Cholesterol	0.3	0.5	0.9	1.0	-0.2
Schizophrenia (2014)	0.3	0.7	0.8	0.9	-0.8
Systolic Blood Pressure	0.3	1.5	2.0	-1.4	-1.0
Hand grip strength (left)	0.3	0.8	1.1	-1.1	-0.7
Systolic blood pressure, automated reading	0.3	0.8	1.0	-1.0	-0.7
Average weekly fortified wine intake	0.3	0.4	0.5	-0.7	-0.4
Supplements: Glucosamine	0.3	0.4	0.5	0.7	0.5
Hearing difficulty/problems with background noise	0.3	0.4	0.6	0.8	0.5
Illnesses of mother	0.3	0.4	0.4	0.6	0.7
Bipolar Disorder (2011)	0.2	0.2	0.3	-0.6	0.0
Type 2 Diabetes (T2D) (2012)	0.2	0.2	0.3	-0.6	-0.4
Blood Red Count	0.2	2.0	3.9	-2.0	0.4
Lung FEV1/FVC ratio	0.2	0.9	1.7	-1.3	-0.1
Hair Pigment	0.2	4.5	6.2	-1.7	-2.5
Tanning	0.2	2.1	2.6	-1.6	-1.2
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.2	-0.5	0.5
Vitamin and mineral supplements	0.2	0.3	0.5	-0.7	-0.2
Diabetes (mother)	0.2	0.3	0.5	-0.7	0.0
Townsend deprivation index at recruitment	0.2	0.3	0.4	-0.4	-0.7
High blood pressure	0.2	0.6	0.7	-0.7	-0.8
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	0.5	-0.2	0.7
High blood pressure (mother)	0.2	0.3	0.4	0.5	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	-0.1	-0.7
Length of working week for main job	0.2	0.2	0.4	0.6	0.2
Hair/balding pattern: Pattern 4	0.2	0.4	0.6	0.4	-0.8
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.6	0.8	0.0
Eye problems/disorders: None of the above	0.2	0.2	0.3	0.6	0.2
Pulse rate, automated reading	0.2	0.8	1.3	-1.1	-0.5
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.5	0.7	-0.2
Hearing aid user	0.2	0.2	0.3	-0.5	-0.4
Medication: Bendroflumethiazide	0.2	0.3	0.4	-0.6	-0.4
Illnesses of father: High blood pressure	0.2	0.2	0.3	0.3	-0.6
Pack years of smoking	0.2	0.3	0.4	-0.5	-0.6
Fasting Glucose	0.1	0.2	0.3	0.2	0.6
Rheumatoid Arthritis	0.1	0.1	0.2	0.3	0.4
Waist Hip Ratio (WHR)	0.1	0.3	0.6	-0.8	0.2
Allergy or Eczema	0.1	0.2	0.3	0.6	-0.2
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.3	0.6	0.0
Hayfever, allergic rhinitis or eczema	0.1	0.2	0.2	0.4	-0.4
Had menopause	0.1	0.1	0.2	0.0	-0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.1	-0.0	0.4
Medication: Simvastatin	0.1	0.1	0.2	-0.1	-0.5
Birth weight	0.1	0.2	0.3	0.5	0.2
Medication: Allopurinol	0.1	0.1	0.2	-0.4	-0.3
Suffer from ‘nerves’	0.1	0.1	0.2	-0.5	0.1
Hypertension (Self-reported)	0.1	0.4	0.4	-0.5	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.1	0.3	-0.3
Eye problems/disorders: Cataract	0.1	0.1	0.1	-0.3	0.2
Medication: Blood pressure	0.1	0.1	0.1	-0.3	-0.3
Myopia	0.1	0.2	0.4	0.1	-0.6
Triglycerides	0.0	0.0	0.1	0.2	0.1
Blood Platelet Count	0.0	0.5	1.1	0.1	-1.0
Height	0.0	0.3	0.6	0.2	0.8
Hearing difficulty/problems: Yes	0.0	0.0	0.0	0.1	-0.0
Angina	0.0	0.1	0.1	-0.3	-0.1
Multivitamins +/- minerals	0.0	0.0	0.0	0.0	0.1
Sitting height	0.0	0.1	0.2	0.1	-0.4
Standing height	0.0	0.1	0.1	0.1	0.3
Medication: Amlodipine	0.0	0.0	0.0	0.1	-0.1
Angina (self-reported)	0.0	0.0	0.0	0.0	0.2
Illnesses of father: Heart disease	0.0	0.1	0.1	0.3	-0.2
Illnesses of father: None of the above (group 1)	0.0	0.0	0.0	-0.1	-0.0
Tinnitus: Yes, now most or all of the time	0.0	0.0	0.0	0.2	0.2
Alcohol drinker status: Never	0.0	0.1	0.1	0.2	0.2
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.1	-0.2	0.1
Fractured/broken bones in last 5 years	0.0	0.0	0.1	0.1	0.3

Hub : Genes

SLC38A3

Models

Trait associations