TWAS hub - SLC39A14

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Bladder Urothelial Carcinoma	0.0360	0.0210	0.00710	0.018	0.023	0.031	NA	0.030	0.0110	4.7e-03	1.1e-03	NA	0.00130
2	TCGA	Breast Invasive Carcinoma	0.0225	0.0133	0.00035	0.010	0.011	0.009	NA	0.010	0.0028	1.6e-03	4.2e-03	NA	0.00340
3	TCGA	Pheochromocytoma and Paraganglioma	0.3540	0.1170	0.00035	0.013	0.153	0.135	NA	0.072	0.0980	1.2e-06	5.0e-06	NA	0.00083

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Frequency of tiredness / lethargy in last 2 weeks	10.2	16.6	24.4	4.9	4.9	-1.1
Average weekly red wine intake	6.4	9.4	14.4	-3.7	-3.8	0.1
Eye problems/disorders: None of the above	6.1	7.0	13.2	3.6	2.8	-0.2
Systolic blood pressure, automated reading	5.4	15.8	20.0	4.5	4.4	-2.8
Overall health rating	4.6	9.9	16.2	3.5	4.0	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	4.1	5.5	8.2	2.9	2.9	-0.1
Ever used hormone-replacement therapy (HRT)	4.0	5.1	7.0	2.4	2.6	-1.5
Exposure to tobacco smoke outside home	4.0	5.3	7.3	2.7	2.7	-1.2
Mouth/teeth dental problems: Bleeding gums	3.9	5.1	7.6	2.8	2.6	-0.9
Depression (Nagel 2018)	3.7	5.6	8.4	2.9	2.9	0.5
Diastolic blood pressure, automated reading	3.7	11.3	16.1	4.0	3.2	-2.8
Supplements: Zinc	3.4	3.7	10.7	0.1	-0.7	-3.3
Breast cancer (self-reported)	3.4	4.1	6.0	-2.5	-2.4	0.4
Fed-up feelings	3.3	6.1	8.4	2.9	2.8	-1.4
Hayfever/allergic rhinitis (self-reported)	3.3	4.3	7.5	2.0	1.3	-2.7
Fluid intelligence score	3.2	6.7	12.8	-2.6	-3.6	-0.5
Depression (self-reported)	3.1	3.7	5.8	2.3	2.4	-0.3
Shortness of breath walking on level ground	3.1	3.7	5.1	2.0	2.2	1.4
Eye problems/disorders: Cataract	3.1	3.5	5.8	-2.4	-1.9	-1.0
Unable to work because of sickness or disability	3.1	4.0	5.1	1.8	2.3	1.9
High blood pressure	3.0	8.4	12.2	3.5	3.4	-1.2
Hair/balding pattern: Pattern 2	3.0	3.8	6.1	2.5	2.3	-0.5
Schizophrenia (2018)	2.9	6.0	8.8	3.0	2.3	-2.0
Age at first live birth	2.9	5.2	10.5	-2.0	-3.2	-1.0
Loneliness, isolation	2.9	4.1	6.0	2.4	2.4	-0.6
Maternal smoking around birth	2.8	4.1	7.0	2.3	2.6	-0.2
Pain all over the body in last month	2.8	3.0	4.7	1.8	2.2	1.0
Medication for cholesterol	2.8	4.2	4.5	-2.1	-2.1	1.9
Frequency of depressed mood in last 2 weeks	2.7	3.8	6.4	2.5	2.2	-0.3
Chest pain or discomfort	2.7	3.9	8.8	1.4	1.1	-3.0
Cholesterol lowering medication	2.7	3.9	6.5	2.0	2.6	-1.1
Supplements: Vitamin C	2.6	3.1	4.0	-1.3	-2.0	-1.9
Sensitivity / hurt feelings	2.5	4.3	6.4	2.5	2.5	-0.6
Financial difficulties in last 2 years	2.5	3.4	7.1	1.4	1.0	-2.7
Hypertension (Self-reported)	2.5	7.0	10.1	3.2	3.1	-1.1
Medication: Simvastatin	2.4	3.6	4.2	2.0	2.0	-1.6
Medication: Amlodipine	2.4	3.3	5.6	2.1	2.4	-0.2
Medication: Ventolin 100micrograms inhaler	2.4	3.1	5.0	2.2	1.9	-0.9
High blood pressure (siblings)	2.4	3.5	5.8	1.7	2.4	1.4
Leg fat percentage (right)	2.4	8.8	13.3	3.6	3.5	-0.9
Leg fat percentage (left)	2.4	8.8	13.1	3.6	3.5	-1.1
Suffer from ‘nerves’	2.3	3.7	5.8	2.4	2.1	-0.9
Medication: Lisinopril	2.3	2.9	4.8	-1.8	-2.2	-0.9
Intelligence (Savage-Jansen 2018)	2.2	6.7	10.0	-2.7	-3.2	1.6
Rheumatoid Arthritis	2.2	3.0	4.0	-1.9	-2.0	1.2
Schizophrenia (2014)	2.2	4.8	6.6	2.6	2.1	-1.8
Medication: Metformin	2.2	3.2	5.8	1.4	2.4	1.3
Number of live births	2.2	3.1	4.8	2.1	2.2	-0.1
Illnesses of mother	2.2	2.8	4.3	-2.0	-2.1	-0.2
Tinnitus: Yes, now most or all of the time	2.2	2.5	5.2	1.3	0.8	-2.3
Medication: Blood pressure	2.2	4.2	6.2	2.3	2.5	-1.1
Systolic Blood Pressure	2.1	10.6	15.3	3.9	3.4	-2.2
Standing height	2.1	21.2	35.2	-5.3	-5.9	0.4
Wheeze or whistling in the chest in last year	2.1	3.7	5.5	2.3	2.2	-1.0
Heart disease (mother)	2.1	2.5	6.8	-0.3	-0.9	-2.6
Illnesses of siblings: Diabetes	2.1	2.6	5.4	1.5	2.3	0.5
Average weekly champagne plus white wine intake	2.1	2.9	3.7	-1.9	-1.9	1.1
Alcohol drinker status: Never	2.1	2.5	6.4	-1.0	0.1	2.5
Frequency of tenseness / restlessness in last 2 weeks	2.0	3.1	5.3	2.3	1.9	-0.5
Qualifications: A levels/AS levels or equivalent	2.0	4.5	6.5	-2.6	-2.5	0.8
Comparative body size at age 10	2.0	5.5	9.5	-2.5	-3.1	-0.8
Medication: Allopurinol	2.0	2.6	4.5	-1.2	-1.4	2.1
Alcohol intake frequency.	2.0	4.5	6.7	2.2	2.6	1.4
Comparative height size at age 10	2.0	11.1	18.7	-3.8	-4.3	0.1
Nervous feelings	1.9	3.6	4.9	2.2	1.8	-1.6
Mouth/teeth dental problems	1.9	2.9	5.2	-1.7	-2.3	0.7
Birth weight	1.9	4.2	8.1	-1.2	-1.7	-2.9
Qualifications: College or University degree	1.9	6.1	10.9	-2.7	-3.3	0.2
Alcohol usually taken with meals	1.8	3.0	3.5	-1.9	-1.9	-1.4
Verbal and Numeric Reasoning (VNR)	1.7	4.2	7.4	-2.1	-2.7	0.9
Crohns Disease (2012)	1.7	2.7	5.0	1.4	1.0	-2.2
HDL Cholesterol	1.7	2.9	4.9	-2.2	-1.4	1.4
Father’s age at death	1.7	2.3	4.0	-2.0	-1.7	0.0
Arm fat percentage (left)	1.7	7.0	10.9	3.2	3.3	-0.2
Supplements: Calcium	1.7	1.9	2.7	1.0	1.4	-1.7
Cardiovascular Disease	1.6	5.3	8.2	2.9	2.5	-1.1
Illnesses of siblings	1.6	2.3	4.0	-1.5	-2.0	-0.8
Arm fat percentage (right)	1.6	6.3	10.2	3.0	3.2	0.1
Breastfed as a baby	1.6	2.0	2.9	-1.7	-1.7	0.4
Financial situation satisfaction	1.6	1.9	5.5	0.5	-0.2	-2.3
Average weekly beer plus cider intake	1.6	2.3	3.8	1.8	2.0	0.0
Ever had prostate specific antigen (PSA) test	1.6	1.9	2.5	1.0	1.6	1.4
Vascular/heart problems diagnosed by doctor	1.6	4.5	6.5	-2.5	-2.3	1.3
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	2.8	1.7	1.1	-0.9
Body fat percentage	1.5	5.7	9.0	2.9	3.0	-0.1
Risk taking	1.5	2.1	4.4	-0.6	-1.3	-2.1
Bipolar Disorder or Schizophrenia	1.4	3.3	4.5	2.1	1.6	-1.7
Alzheimer’s Disease (in mother)	1.4	1.7	2.9	1.4	1.7	-0.5
Hearing difficulty/problems: Yes	1.4	2.1	3.6	1.4	0.8	-1.9
Hand grip strength (right)	1.4	3.8	7.0	-2.0	-2.6	-0.6
Hayfever, allergic rhinitis or eczema	1.4	2.9	5.6	1.4	1.1	-2.4
Birth weight of first child	1.4	2.5	3.9	-1.8	-2.0	0.8
Medication: Ibuprofen	1.4	1.7	4.7	-0.6	0.2	2.2
Commuting to job workplace: Walk	1.4	1.5	2.6	-1.6	-1.4	0.4
Mouth/teeth dental problems: Mouth ulcers	1.4	2.1	4.3	1.4	2.1	0.2
Neuroticism (Nagel 2018)	1.3	3.1	5.3	2.3	1.8	-0.9
Ulcerative Colitis	1.3	1.9	2.6	-1.6	-1.6	-0.6
Type 2 Diabetes (T2D) (2018)	1.3	2.4	6.9	-0.4	0.3	2.6
Average weekly spirits intake	1.3	1.6	2.2	-1.2	-1.5	1.1
Diabetes (mother)	1.3	1.7	4.0	-0.9	-0.7	2.0
Body mass index (BMI)	1.3	5.5	8.4	2.7	2.9	-0.8
Heart attack	1.3	1.6	2.2	1.1	1.2	-1.5
Time employed in main current job	1.3	1.5	2.4	-1.6	-1.3	0.6
Qualifications: O levels/GCSEs or equivalent	1.3	2.0	3.4	-1.5	-0.8	1.8
Age at last live birth	1.3	1.9	4.3	-0.8	-2.1	-0.8
Smoking status: Previous	1.3	1.9	2.6	1.6	1.0	-1.5
Handedness (chirality/laterality): Left-handed	1.3	1.5	2.2	1.5	1.4	-0.6
Qualifications: nursing, teaching	1.3	2.0	3.0	-1.3	-1.2	1.7
Medication: Bendroflumethiazide	1.3	1.9	2.5	1.4	1.1	-1.6
Schizophrenia vs Biploar Disorder	1.2	1.6	3.1	1.3	1.8	0.2
Coronary Artery Disease (CAD)	1.2	1.5	2.2	1.3	1.5	0.6
Neuroticism (2016)	1.2	1.7	2.7	1.4	0.6	-1.6
Medication for hormone replacement therapy	1.2	1.3	3.1	0.8	0.4	-1.8
Hearing difficulty/problems with background noise	1.2	1.8	3.5	1.4	1.9	0.0
Tense / ‘highly strung’	1.2	2.0	2.2	1.5	1.3	-1.5
Number of children fathered	1.2	1.3	3.0	0.8	0.4	-1.7
Migraine (self-reported)	1.2	1.5	2.4	-1.4	-1.6	-0.1
Number of self-reported non-cancer illnesses	1.2	2.2	2.5	1.6	1.3	-1.6
Reaction Time	1.1	2.1	5.1	-0.8	-0.7	2.3
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	2.4	-0.9	-0.7	1.6
Had menopause	1.1	1.4	3.0	1.0	1.7	-0.0
Trunk fat-free mass	1.1	6.2	10.4	-2.8	-3.2	-0.4
Prospective memory result	1.1	1.3	1.5	1.2	1.2	-1.0
Trunk predicted mass	1.1	6.2	10.7	-2.8	-3.3	-0.4
Loud music exposure frequency	1.1	1.2	2.8	1.0	0.3	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	2.0	1.3	1.4	0.8
Illness, injury, bereavement, stress in last 2 years	1.1	1.4	2.8	-0.9	-0.8	1.7
Long-standing illness, disability or infirmity	1.1	1.7	3.2	1.8	1.3	-0.4
Ever smoked	1.1	1.8	4.9	0.5	-0.6	-2.2
Alzheimer’s Disease (in father)	1.0	1.1	2.1	-0.9	-0.5	1.5
Body Mass Index (BMI) (2010)	1.0	1.3	2.4	1.1	0.4	-1.6
Hand grip strength (left)	1.0	2.8	4.8	-1.0	-2.2	-1.5
Ever had hysterectomy (womb removed)	1.0	1.2	2.1	1.1	1.4	0.6
Medication: Levothyroxine sodium	1.0	1.6	2.7	-0.7	-1.3	-1.6
Forced vital capacity (FVC), Best measure	1.0	3.6	5.0	-1.9	-2.2	-1.4
Health satisfaction	1.0	1.3	2.3	1.3	1.5	-0.1
Irritability	1.0	1.7	2.9	1.7	1.4	-0.5
Crohns Disease (2017)	0.9	2.0	2.5	1.6	1.5	-1.2
Allergy or Eczema	0.9	2.5	6.9	0.6	0.3	-2.6
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	2.2	-0.6	-1.0	-1.5
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	2.9	-1.6	-1.7	0.8
Medication: Atenolol	0.9	1.1	1.8	1.3	1.4	0.2
Forced vital capacity (FVC)	0.9	3.4	4.6	-1.8	-2.1	-1.5
Ever unenthusiastic/disinterested for a whole week	0.9	1.1	2.7	0.8	0.3	-1.6
Allergy	0.9	2.0	5.8	-0.5	-0.3	2.4
Neuroticism score	0.9	1.9	3.5	1.9	1.3	-0.8
Alcohol intake versus 10 years previously	0.9	1.3	2.2	1.5	1.3	0.3
Hair/balding pattern: Pattern 3	0.9	1.3	1.6	-1.0	-1.1	-1.3
Noisy workplace	0.9	1.1	2.2	1.5	0.9	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.8	4.7	-1.9	-2.2	-0.6
Chronic bronchitis/emphysema (mother)	0.9	1.1	2.0	0.7	0.9	1.4
Leg fat mass (right)	0.9	3.4	5.0	2.2	2.2	-0.6
Number of full sisters	0.9	1.1	1.9	0.4	1.1	1.4
Guilty feelings	0.9	1.3	2.4	1.5	1.3	-0.3
High cholesterol (Self-reported)	0.9	1.7	2.4	1.5	1.4	-0.7
Pack years of smoking	0.9	1.3	2.0	1.4	1.1	-0.8
Leg fat mass (left)	0.9	3.6	5.5	2.3	2.2	-0.6
Blood Platelet Count	0.8	9.3	14.2	-3.8	-3.6	0.7
Lung FEV1/FVC ratio	0.8	4.1	4.5	-2.1	-2.1	1.9
Medication: Co-codamol	0.8	0.9	2.6	0.1	-0.2	-1.6
Pack years adult smoking proportion	0.8	1.2	1.9	1.4	1.1	-0.8
Trunk fat percentage	0.8	3.3	5.7	2.1	2.4	0.2
Chronic bronchitis/emphysema (father)	0.8	0.9	1.7	1.0	0.2	-1.3
Had other major operations	0.8	1.0	2.1	0.9	1.5	0.1
Exposure to tobacco smoke at home	0.8	0.9	1.6	1.0	1.3	-0.2
Pulse wave peak to peak time	0.8	1.0	1.3	-1.2	-1.1	0.6
Smoking status: Current	0.8	1.3	2.0	-1.2	-1.4	0.7
Heart attack/myocardial infarction (self-reported)	0.8	1.0	1.8	0.6	0.9	-1.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	1.9	1.0	1.4	0.4
Height	0.7	12.8	21.2	-4.1	-4.6	0.4
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	1.4	-0.9	0.3	1.2
Diabetes (father)	0.7	0.9	1.7	0.9	1.3	-0.1
Average weekly fortified wine intake	0.7	0.8	1.3	-0.8	-0.7	1.1
Taking other prescription medications	0.7	1.0	1.6	1.3	1.2	-0.1
Medication: Ramipril	0.7	0.9	1.6	0.9	0.6	-1.3
Medication: Lansoprazole	0.7	0.8	1.3	-1.1	-1.2	-0.3
Lung cancer (father)	0.7	0.9	1.6	1.0	1.3	0.3
Length of working week for main job	0.7	0.8	1.4	-1.2	-0.1	0.9
Ever highly irritable/argumentative for 2 days	0.7	0.9	1.5	0.8	0.6	-1.2
Arm fat-free mass (right)	0.7	3.7	6.0	-2.1	-2.4	-1.0
Emphysema/chronic bronchitis	0.7	0.8	2.1	0.2	0.4	-1.5
Arm predicted mass (right)	0.7	3.6	5.6	-2.0	-2.4	-1.1
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.4	1.0	1.2	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	2.0	-1.4	-1.2	0.8
Whole body water mass	0.7	3.9	6.3	-2.3	-2.5	-0.2
Medication: Paracetamol	0.7	1.1	3.2	0.1	-0.0	1.8
Illnesses of father: High blood pressure	0.7	0.9	1.1	-0.9	-0.8	-1.1
Alcohol drinker status: Previous	0.7	0.8	1.6	1.3	0.8	-0.3
Ulcerative Colitis (UC)	0.6	1.2	1.6	-1.2	-1.3	-0.7
Chronotype (morning person)	0.6	1.3	3.2	-0.3	-0.8	-1.8
Townsend deprivation index at recruitment	0.6	0.9	2.3	0.4	0.4	-1.5
Current tobacco smoking	0.6	0.9	1.0	-0.9	-1.0	1.0
Qualifications: CSEs or equivalent	0.6	0.8	1.7	1.3	0.9	0.2
Multivitamins +/- minerals	0.6	0.8	1.4	-1.2	-0.8	0.6
Forced expiratory volume in 1-second (FEV1)	0.6	2.2	3.7	-1.6	-1.9	-0.4
Arm fat mass (right)	0.6	2.5	4.1	1.9	2.0	-0.1
Medication: Paracetamol	0.6	1.0	2.8	-0.4	-0.3	1.7
Gout (self-reported)	0.6	0.8	2.3	-0.0	0.1	1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.6	0.3	-0.7	-1.3
Whole body fat-free mass	0.6	3.6	6.0	-2.2	-2.4	-0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.7	-0.6	-0.2	1.3
Illnesses of father: None of the above (group 1)	0.6	0.8	1.4	-0.3	-0.9	-1.2
Arm fat mass (left)	0.6	2.3	3.5	1.8	1.9	-0.3
Commuting to job workplace: Public transport	0.6	0.7	1.1	-0.9	-1.0	-0.4
Arm fat-free mass (left)	0.6	2.9	4.6	-1.9	-2.1	-0.6
Myopia	0.6	0.8	1.2	1.1	1.1	0.1
Heart disease (siblings)	0.6	0.7	1.9	-0.4	-0.2	1.4
Arm predicted mass (left)	0.6	3.1	5.1	-2.0	-2.2	-0.6
Alzheimer’s Disease (including proxy)	0.5	0.7	1.3	0.9	1.1	0.3
Major Depression (MDD)	0.5	0.6	0.9	0.7	0.9	0.7
LDL Cholesterol	0.5	0.8	0.9	0.9	1.0	-0.8
Lupus	0.5	0.7	1.3	0.3	1.2	0.8
Triglycerides	0.5	0.8	2.2	0.4	-0.3	-1.5
Lung FVC	0.5	2.5	7.5	0.3	0.0	-2.7
Sitting height	0.5	3.5	5.2	-1.4	-2.3	-1.8
Past tobacco smoking	0.5	1.0	2.3	-0.8	-0.1	1.5
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	1.4	-1.2	-1.1	0.9
Happiness	0.5	0.6	1.1	1.0	0.3	0.9
Medication: Cholesterol lowering	0.5	0.7	1.1	1.1	0.8	-0.5
Pulse wave Arterial Stiffness index	0.5	0.6	0.9	1.0	0.8	-0.6
Pulse wave reflection index	0.5	0.6	1.0	0.8	1.0	0.3
Glaucoma (self-reported)	0.5	0.6	1.6	-0.2	-0.4	-1.3
Number of full brothers	0.5	0.6	1.5	-0.5	0.3	1.2
Whole body fat mass	0.5	2.0	3.1	1.7	1.8	-0.1
Mood swings	0.5	0.9	1.5	1.2	0.9	-0.5
Ever had bowel cancer screening	0.5	0.5	1.6	0.2	-0.2	-1.3
Diabetes diagnosed by doctor	0.5	0.8	1.2	0.6	1.1	0.9
Osteoarthritis (self-reported)	0.5	0.6	1.0	-0.8	-1.0	-0.2
Hearing aid user	0.5	0.6	0.7	-0.7	-0.6	-0.9
Eye problems/disorders: Glaucoma	0.5	0.6	0.9	-0.7	-0.8	-0.9
Pain type(s) experienced in last month: Hip pain	0.5	0.6	0.8	0.9	0.7	-0.8
Age started oral contraceptive pill	0.5	0.7	2.0	0.0	0.2	-1.4
Depressed Affect (Nagel 2018)	0.4	0.9	1.4	1.2	1.0	-0.6
Worry (Nagel 2018)	0.4	0.7	1.2	1.1	0.4	-0.9
Age at First Birth	0.4	0.5	1.4	0.0	-0.4	-1.2
Primary Biliary Cirrhosis	0.4	0.5	1.3	0.1	0.4	1.2
BMI	0.4	2.6	3.7	1.9	1.9	-0.8
Waist Hip Ratio (WHR)	0.4	1.8	2.3	-1.5	-1.2	1.4
Respiratory disease	0.4	1.0	2.6	-0.3	-0.5	-1.6
Neuroticism	0.4	1.0	1.9	1.4	1.0	0.2
Number of treatments/medications taken	0.4	0.8	1.1	1.0	1.1	-0.4
Vitamin and mineral supplements	0.4	0.5	0.6	0.8	0.8	0.5
Severe depression (siblings)	0.4	0.4	1.1	-0.5	-1.0	0.0
Supplements: Glucosamine	0.4	0.5	1.5	0.1	-0.0	-1.2
Pulse rate	0.4	0.6	1.0	-0.8	-0.6	-1.0
Blood clot in the leg (DVT)	0.4	0.5	1.0	0.6	1.0	0.4
Mean time to correctly identify matches	0.4	0.8	2.3	-0.0	0.1	1.5
Had major operations	0.4	0.5	0.8	0.9	0.6	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	0.9	0.6	0.9	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.1	-0.3	-0.5	-1.0
Friendships satisfaction	0.4	0.5	1.0	0.8	1.0	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.4	0.3	-0.0	-1.2
Back pain experienced in last month	0.4	0.6	0.8	0.7	0.7	-0.9
Mineral and other dietary supplements	0.4	0.5	0.8	-0.5	-0.7	0.9
Wears glasses or contact lenses	0.4	0.5	1.3	-0.4	-0.1	1.1
Ever taken oral contraceptive pill	0.4	0.4	0.9	-0.3	-0.4	-1.0
Blood Eosinophil Count	0.3	2.7	4.0	-1.7	-2.0	1.1
Heel T-Score	0.3	2.5	4.2	-1.6	-2.0	-0.9
Smoking Status	0.3	0.7	1.2	-0.9	-1.1	0.4
Relative age of first facial hair	0.3	0.6	1.4	0.4	0.4	-1.2
Relative age voice broke	0.3	0.5	0.7	0.8	0.5	-0.8
Serious illness, injury or assault to yourself	0.3	0.4	0.5	0.6	0.7	0.7
High blood pressure (mother)	0.3	0.4	0.6	0.5	0.8	0.6
Trunk fat mass	0.3	1.4	2.3	1.4	1.5	-0.0
Waist circumference	0.3	1.2	1.8	1.3	1.3	0.1
Qualifications: None of the above	0.3	0.6	0.8	0.9	0.8	-0.5
Impedance of arm (right)	0.3	1.3	3.8	-0.1	0.1	1.9
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	0.8	-0.4	0.0	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	0.9	1.0	0.3	-0.7
Headache pain in last month	0.3	0.5	0.7	-0.8	-0.8	-0.3
Neck or shoulder pain in last month	0.3	0.5	1.3	0.1	0.2	-1.2
Medication: Blood pressure	0.3	0.4	0.8	0.9	0.7	0.3
Pulse rate, automated reading	0.3	0.8	1.9	-0.3	-0.7	-1.4
Knee pain experienced in last month	0.3	0.4	1.1	0.3	1.1	0.3
Illnesses of father: Heart disease	0.3	0.5	0.8	0.9	0.7	-0.3
Leg fat-free mass (right)	0.3	1.4	2.1	-1.5	-1.4	0.0
Asthma (self-reported)	0.3	0.6	1.5	0.6	0.2	-1.2
Mother’s age at death	0.3	0.3	0.5	-0.5	-0.7	0.5
Supplements: Fish oil (including cod liver oil)	0.3	0.3	0.8	-0.4	-0.2	-0.9
Basal metabolic rate	0.3	1.8	3.0	-1.5	-1.7	-0.3
Number of operations (self-reported)	0.3	0.4	0.5	0.5	0.7	0.6
Commuting to job workplace: Cycle	0.3	0.3	0.6	-0.8	-0.5	0.4
Irritable Bowel Disease (IBD)	0.2	0.4	1.3	0.0	0.0	-1.1
Ovarian Cancer	0.2	0.3	0.6	-0.6	-0.8	-0.0
Prostate Cancer	0.2	0.3	0.5	-0.5	-0.7	0.5
Blood Red Count	0.2	2.0	3.6	1.9	1.5	0.2
Angina	0.2	0.3	0.7	-0.3	-0.8	-0.0
Leg fat-free mass (left)	0.2	1.0	1.5	-1.2	-1.2	0.2
Leg predicted mass (left)	0.2	1.0	1.5	-1.2	-1.2	0.1
Number of incorrect matches in round	0.2	0.3	0.5	0.7	0.7	-0.0
Diabetes (self-reported)	0.2	0.2	0.4	-0.5	-0.1	0.7
Hip circumference	0.2	0.7	0.9	0.9	1.0	0.5
Asthma	0.2	0.5	1.2	0.4	0.1	-1.1
Impedance of arm (left)	0.2	1.1	3.1	-0.1	-0.0	1.8
Hair/balding pattern: Pattern 4	0.2	0.5	0.9	-0.6	-0.6	1.0
Peak expiratory flow (PEF)	0.2	0.4	1.0	0.0	-0.4	-1.0
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.7	-0.8	-0.3	0.2
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	0.7	-0.5	-0.8	-0.7
Worry too long after embarrassment	0.2	0.4	0.8	0.2	-0.4	0.9
Medication: Aspirin	0.2	0.3	0.4	-0.6	-0.5	-0.3
Medication: Aspirin	0.2	0.3	0.8	0.0	-0.1	-0.9
Medication: Gliclazide	0.2	0.2	0.5	0.1	-0.1	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.4	0.5	-0.5	-0.7	-0.7
Leg predicted mass (right)	0.2	1.3	2.0	-1.4	-1.4	0.0
Ever depressed for a whole week	0.2	0.3	0.4	0.5	0.4	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	0.3	-0.6	-0.3	0.6
Pain experienced in last month	0.2	0.4	0.7	0.5	-0.3	-0.8
Bipolar Disorder (2018)	0.1	0.1	0.2	-0.2	-0.3	-0.4
Mean Putamen Volume	0.1	0.1	0.2	0.4	0.3	0.3
Fasting Glucose	0.1	0.2	0.5	-0.0	-0.1	-0.7
Blood White Count	0.1	0.9	1.4	-0.9	-1.2	-0.8
Hypothyroidism (self reported)	0.1	0.3	0.4	-0.3	-0.6	-0.6
Tanning	0.1	1.3	2.2	-1.5	-1.2	0.4
Age when periods started (menarche)	0.1	0.3	0.6	-0.3	0.2	0.8
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.2	0.1	-0.4	-0.5
Worrier / anxious feelings	0.1	0.1	0.1	0.2	-0.3	-0.4
Mouth/teeth dental problems: Dentures	0.1	0.2	0.6	0.2	0.4	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.3	-0.5	-0.3	-0.2
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.4	-0.1	-0.2	0.6
Medication for pain relief, constipation, heartburn	0.1	0.2	0.6	0.2	0.2	-0.8
Angina (self-reported)	0.1	0.2	0.4	0.0	-0.6	-0.3
Medication: Omeprazole	0.1	0.1	0.3	-0.2	0.1	0.6
Medication: Seretide 50 evohaler	0.1	0.2	0.2	0.5	-0.4	-0.3
Family relationship satisfaction	0.1	0.2	0.4	0.7	0.2	-0.1
Osteoporosis (self-reported)	0.1	0.2	0.3	-0.5	-0.1	0.5
Medication: Atorvastatin	0.1	0.1	0.3	0.1	0.0	-0.5
Fractured/broken bones in last 5 years	0.1	0.1	0.2	-0.1	-0.3	-0.5
Impedance of whole body	0.1	0.4	1.1	-0.3	-0.3	1.1
Breast Cancer	0.0	0.0	0.0	-0.1	0.1	0.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0
HbA1C	0.0	0.0	0.0	-0.1	-0.1	-0.2
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.1	0.1	-0.0	-0.4
Hair Pigment	0.0	0.1	0.3	-0.2	0.2	-0.5
Impedance of leg (right)	0.0	0.1	0.1	-0.1	-0.4	0.2
Stomach or abdominal pain in last month	0.0	0.0	0.1	-0.2	-0.3	-0.1
Impedance of leg (left)	0.0	0.1	0.2	-0.2	-0.5	0.2
Weight	0.0	0.1	0.2	0.3	0.2	-0.5
Falls in the last year	0.0	0.1	0.1	0.3	0.2	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.1	0.1	0.1	-0.2
Leg pain on walking	0.0	0.0	0.0	0.0	-0.1	-0.1
Miserableness	0.0	0.0	0.0	0.1	-0.0	-0.0
Basal cell carcinoma (self-reported)	0.0	0.0	0.0	-0.0	0.2	-0.2

Hub : Genes

SLC39A14

Models

Trait associations